Ashikari Yosuke 芦刈洋祐

… Alternative Names

Yosuke Ashikari 芦刈洋祐

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Researcher Number	70865584
Other IDs	https://orcid.org/0000-0001-7145-6142
Affiliation (Current)	2025: 北海道大学, 理学研究院, 特任助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 北海道大学, 理学研究院, 特任助教 2020 – 2021: 京都大学, 工学研究科, 研究員
Review Section/Research Field	Principal Investigator Basic Section 33020:Synthetic organic chemistry-related Except Principal Investigator Medium-sized Section 33:Organic chemistry and related fields
Keywords	Principal Investigator カルボカチオン / 電解反応 / フロー反応 / グリコシル化 / フローマイクロ合成 / 有機カチオン / カチオンフロー法 / 不安定活性種 / 電極反応 / 電解合成 / 不安定中間体 … More Except Principal Investigator … More フローマイクロ合成 / 電解酸化 / 超強酸 / カルボカチオン / フロー / マイクロリアクター / グリコシルカチオン / フロー合成 / フローマイクロリアクター Less

高速フロー法を活用したカルボカチオンの性質解明に立脚したグリコシル化反応の開発Principal Investigator
- Principal Investigator
  
  芦刈洋祐
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 33020:Synthetic organic chemistry-related
- Research Institution
  Hokkaido University
Advanced utilization of multiple short-lived reactive species by application of flash flow electrolysisPrincipal Investigator
- Principal Investigator
  
  Yosuke Ashikari
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 33020:Synthetic organic chemistry-related
- Research Institution
  Hokkaido University
  Kyoto University
糖化学の新展開のための非平衡カルボカチオン化学のネットワーク構築
- Principal Investigator
  
  永木愛一郎
- Project Period (FY)
  2020 – 2025
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 33:Organic chemistry and related fields
- Research Institution
  Hokkaido University
  Kyoto University

All 2024 2023 2022 2021 2020

All Journal Article Presentation Book

[Book] Enabling Tools and Techniques for Organic Synthesis: A Practical Guide to Experimentation, Automation, and Computation2023
- Author(s)
  Ashikari, Y.; Nagaki, A.
- Total Pages
  496
- Publisher
  Wiley
- ISBN
  9781119855637
- Data Source
  KAKENHI-PROJECT-20KK0121
[Book] 実験の自動化・自律化によるR&Dの効率化と運用方法　－AI、ロボット技術、ChatGPT、MI、ベイズ最適化、秘密計算など－2023
- Author(s)
  芦刈洋祐、玉木孝、永木愛一郎
- Total Pages
  545
- Publisher
  技術情報協会
- ISBN
  9784861049941
- Data Source
  KAKENHI-PROJECT-20KK0121
[Book] マイクロ・ナノ熱工学の進展2021
- Author(s)
  芦刈洋祐、永木愛一郎
- Total Pages
  808
- Publisher
  株式会社エヌ・ティーエス
- ISBN
  9784860437220
- Data Source
  KAKENHI-PROJECT-20KK0121
[Book] フロー合成、連続生産のプロセス設計、条件設定と応用事例2020
- Author(s)
  芦刈洋祐ほか
- Total Pages
  599
- Publisher
  技術情報協会
- ISBN
  9784861048203
- Data Source
  KAKENHI-PROJECT-20K15276
[Book] マイクロリアクター/フロー合成による反応条件を最適化した導入と目的に応じた実生産への適用2020
- Author(s)
  芦刈洋祐ほか
- Total Pages
  270
- Publisher
  サイエンス＆テクノロジー社
- ISBN
  9784864282116
- Data Source
  KAKENHI-PROJECT-20K15276
[Journal Article] Flowmicro In-Line Analysis-Driven Design of Reactions mediated by Unstable Intermediates: Flash Monitoring Approach2024
- Author(s)
  Ashikari, Y.; Yoshioka, R.; Yonekura, Y.; Yoo, D. E.; Okamoto, K.; Nagaki, A.
- Journal Title
  
  ChemEurJ
  
  Volume: 30 Issue: 18
- DOI
  10.1002/chem.202303774
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20KK0121, KAKENHI-PLANNED-21H05080
[Journal Article] Highly productive flow synthesis for lithiation, borylation, and/or Suzuki coupling reaction2024
- Author(s)
  Soutome, H.; Maekawa, K.; Ashikari, Y.; Nagaki, A.
- Journal Title
  
  Org. Process Res. Dev.
  
  Volume: - Issue: 5 Pages: 2006-2012
- DOI
  10.1021/acs.oprd.4c00021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20KK0121, KAKENHI-PLANNED-21H05080
[Journal Article] Elucidation of the kinetic stabilities of carbenoid species by integration of theoretical and experimental studies2024
- Author(s)
  Okamoto, K.; Muta, K.; Yamada, H.; Higuma, R.; Ashikari, Y.; Nagaki, A.
- Journal Title
  
  React. Chem. Eng.
  
  Volume: - Issue: 5 Pages: 1173-1178
- DOI
  10.1039/d3re00648d
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20KK0121, KAKENHI-PROJECT-20K12252, KAKENHI-PROJECT-23K04744, KAKENHI-PROJECT-20K05595, KAKENHI-PLANNED-21H05080
[Journal Article] One-flow operation via 4-bromopyridine enables flash synthesis of AChE inhibitor2024
- Author(s)
  Soutome, H.; Kimuro, Y.; Kawaguchi, T.; Yoo, D. E.; Yao, Y.; Oshida, S.; Nakayama, H.; Iwata, M.; Ebisawa, R.; Kikuchi, R.; Tomite, K.; Wada, S.; Ashikari, Y.; Nagaki, A.
- Journal Title
  
  Synthesis
  
  Volume: 56 Issue: 05 Pages: 821-827
- DOI
  10.1055/a-2218-9048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20KK0121, KAKENHI-PLANNED-21H05080
[Journal Article] External Flash Generation of Carbenoids Enables Monodeuteration of Dihalomethanes2023
- Author(s)
  Okamoto, K.; Higuma, R.; Muta, K.; Fukumoto, K.; Tsuchihashi, Y.; Ashikari, Y.; Nagaki, A.
- Journal Title
  
  Chem. Eur. J.
  
  Volume: 29 Issue: 47
- DOI
  10.1002/chem.202301738
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20KK0121, KAKENHI-PROJECT-23K04744, KAKENHI-PLANNED-21H05080
[Journal Article] Continuous enantiomeric separation using water-oil-water segmented flow system2023
- Author(s)
  Muranaka, Y.; Maki, T.; Nakayoshi, D.; Asano, S.; Ikebata, K.; Nagaki, A.; Ashikari, Y.; Mandai, K.; Mae, K.
- Journal Title
  
  Chem. Eng. J.
  
  Volume: 469 Pages: 143891-143891
- DOI
  10.1016/j.cej.2023.143891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20KK0121, KAKENHI-PLANNED-21H05080
[Journal Article] Electrocatalytic Reduction of (Hetero)Aryl Halides in a Proton-Exchange Membrane Reactor and its Application for Deuteration2023
- Author(s)
  Ashikari, Y.; Mandai, K.; Yao, Y.; Tsuchihashi, Y.; Nagaki, A.
- Journal Title
  
  ChemElectroChem
  
  Volume: 10 Issue: 23
- DOI
  10.1002/celc.202300315
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20KK0121, KAKENHI-PLANNED-21H05080
[Journal Article] フローマイクロケミストリーに基づく反応集積化2022
- Author(s)
  永木愛一郎、芦刈洋祐
- Journal Title
  
  ケミカルタイムス
  
  Volume: 263 Pages: 3-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15276
[Journal Article] Flash functional group-tolerant biaryl-synthesis based on integration of lithiation, zincation and negishi coupling in flow2022
- Author(s)
  Ashikari Yosuke、Guan Kaiteng、Nagaki Aiichiro
- Journal Title
  
  Frontiers in Chemical Engineering
  
  Volume: 4 Pages: 964767-964767
- DOI
  10.3389/fceng.2022.964767
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20KK0121, KAKENHI-PLANNED-21H05080, KAKENHI-PROJECT-20K15276, KAKENHI-PROJECT-23K21114
[Journal Article] Flow grams-per-hour production enabled by hierarchical bimodal porous silica gel supported palladium column reactor having low pressure drop2022
- Author(s)
  Ashikari Yosuke、Maekawa Kei、Takumi Masahiro、Tomiyasu Noriyuki、Fujita Chiemi、Matsuyama Kiyoshi、Miyamoto Riichi、Bai Hongzhi、Nagaki Aiichiro
- Journal Title
  
  Catalysis Today
  
  Volume: 388-389 Pages: 231-236
- DOI
  10.1016/j.cattod.2020.07.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22186, KAKENHI-PROJECT-20K05214, KAKENHI-PROJECT-20K15276, KAKENHI-PROJECT-20KK0121
[Journal Article] Investigation of Parameter Control for Electrocatalytic Semihydrogenation in a Proton-Exchange Membrane Reactor Utilizing Bayesian Optimization2022
- Author(s)
  Ashikari Yosuke、Tamaki Takashi、Takahashi Yusuke、Yao Yiyue、Atobe Mahito、Nagaki Aiichiro
- Journal Title
  
  Frontiers in Chemical Engineering
  
  Volume: 3 Pages: 819752-819752
- DOI
  10.3389/fceng.2021.819752
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22186, KAKENHI-PROJECT-20K21106, KAKENHI-PLANNED-21H05215, KAKENHI-PROJECT-20H02513, KAKENHI-PROJECT-20K15276, KAKENHI-PROJECT-20KK0121, KAKENHI-PLANNED-21H05080
[Journal Article] フロー高速合成とAI活用の将来展望について2021
- Author(s)
  永木愛一郎、芦刈洋祐、宅見正浩
- Journal Title
  
  化学工学
  
  Volume: 85 Pages: 611-614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15276
[Journal Article] Multiple Organolithium Reactions for Drug Discovery Using Flash Chemistry2021
- Author(s)
  Ashikari Yosuke、Tamaki Takashi、Takumi Masahiro、Nagaki Aiichiro
- Journal Title
  
  Topics in Medicinal Chemistry
  
  Volume: 0 Pages: 223-239
- DOI
  10.1007/7355_2021_113
- ISBN
  9783030855918, 9783030855925
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15276, KAKENHI-PLANNED-21H05080
[Journal Article] Flash Chemistry Makes Impossible Organolithium Chemistry Possible2021
- Author(s)
  Aiichiro Nagaki, Yosuke Ashikari, Masahiro Takumi, Takashi Tamaki
- Journal Title
  
  Chemistry Letters
  
  Volume: 50 Issue: 3 Pages: 485-492
- DOI
  10.1246/cl.200837
- NAID
  130007995528
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22186, KAKENHI-PROJECT-20K15276, KAKENHI-PROJECT-20KK0121
[Journal Article] Homogeneous Catalyzed Aryl?Aryl Cross-Couplings in Flow2021
- Author(s)
  Nagaki Aiichiro、Ashikari Yosuke
- Journal Title
  
  Synthesis
  
  Volume: 53 Issue: 11 Pages: 1879-1888
- DOI
  10.1055/a-1360-7798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15276, KAKENHI-PROJECT-20KK0121
[Journal Article] Stille, Heck, and Sonogashira coupling and hydrogenation catalyzed by porous-silica-gel-supported palladium in batch and flow2021
- Author(s)
  Ashikari Yosuke、Maekawa Kei、Ishibashi Mai、Fujita Chiemi、Shiosaki Kiyonari、Bai Hongzhi、Matsuyama Kiyoshi、Nagaki Aiichiro
- Journal Title
  
  Green Processing and Synthesis
  
  Volume: 10 Issue: 1 Pages: 722-728
- DOI
  10.1515/gps-2021-0069
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22186, KAKENHI-PROJECT-20K05214, KAKENHI-PROJECT-20K15276, KAKENHI-PROJECT-20KK0121, KAKENHI-PLANNED-21H05080
[Journal Article] Switchable Chemoselectivity of Reactive Intermediates Formation and Their Direct Use in A Flow Microreactor2021
- Author(s)
  Ashikari Yosuke、Tamaki Takashi、Kawaguchi Tomoko、Furusawa Mai、Yonekura Yuya、Ishikawa Susumu、Takahashi Yusuke、Aizawa Yoko、Nagaki Aiichiro
- Journal Title
  
  Chemistry A European Journal
  
  Volume: 27 Issue: 65 Pages: 16107-16111
- DOI
  10.1002/chem.202103183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22186, KAKENHI-PROJECT-20K15276, KAKENHI-PROJECT-20KK0121, KAKENHI-PLANNED-21H05080
[Journal Article] Accelerating Heat-Initiated Radical Reactions of Organic Halides with Tin Hydride Using Flow Microreactor Technologies2020
- Author(s)
  Yiyuan Jiang, Yosuke Ashikari, Kaiteng Guan, Aiichiro Nagaki
- Journal Title
  
  Synlett
  
  Volume: 31 Issue: 19 Pages: 1937-1941
- DOI
  10.1055/s-0040-1707307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22186, KAKENHI-PROJECT-20K15276, KAKENHI-PROJECT-20KK0121
[Journal Article] Pd catalysts supported on dual-pore monolithic silica beads for chemoselective hydrogenation under batch and flow reaction conditions2020
- Author(s)
  Yamada Tsuyoshi、Ogawa Aya、Masuda Hayato、Teranishi Wataru、Fujii Akiko、Park Kwihwan、Ashikari Yosuke、Tomiyasu Noriyuki、Ichikawa Tomohiro、Miyamoto Riichi、Bai Hongzhi、Matsuyama Kiyoshi、Nagaki Aiichiro、Sajiki Hironao
- Journal Title
  
  Catalysis Science & Technology
  
  Volume: 10 Issue: 18 Pages: 6359-6367
- DOI
  10.1039/d0cy01442g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K05214, KAKENHI-PROJECT-19K22186, KAKENHI-PROJECT-20K15276, KAKENHI-PROJECT-20KK0121, KAKENHI-PROJECT-19J22469
[Journal Article] A Synthetic Approach to Dimetalated Arenes Using Flow Microreactors and the Switchable Application to Chemoselective Cross-Coupling Reactions2020
- Author(s)
  Yosuke Ashikari, Tomoko Kawaguchi, Kyoko Mandai, Yoko Aizawa, Aiichiro Nagaki
- Journal Title
  
  Journal of American Chemical Society
  
  Volume: 142 Issue: 40 Pages: 17039-17047
- DOI
  10.1021/jacs.0c06370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22186, KAKENHI-PROJECT-20K15276, KAKENHI-PROJECT-20KK0121
[Journal Article] Fluoro‐Substituted Methyllithium Chemistry: External Quenching Method Using Flow Microreactors2020
- Author(s)
  Marco Colella, Arianna Tota, Yusuke Takahashi, Ryosuke Higuma, Susumu Ishikawa, Leonardo Degennaro, Renzo Luisi, Aiichiro Nagaki
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 59 Issue: 27 Pages: 10924-10928
- DOI
  10.1002/anie.202003831
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22186, KAKENHI-PROJECT-20KK0121
[Presentation] 高速電解フローリアクターによるグリコシルカチオン種の発生とO-C転位の制御2023
- Author(s)
  姚弋越、宅見正浩、芦刈洋祐、永木愛一郎
- Organizer
  日本化学会第103年会
- Data Source
  KAKENHI-PROJECT-20K15276
[Presentation] Flow micro synthesis based on generation and reactions of aryllithiums bearing highly-coordinated anionic functionalities2021
- Author(s)
  Yosuke Ashikari, Daisuke Ichinari, Kyoko Mandai, Tomoko Kawaguchi, Yoko Aizawa, Aiichiro Nagaki
- Organizer
  The 2021 International Chemical Congress of Pacific Basin Societies (Pacifichem 2021）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15276
[Presentation] 高配位アニオン性置換基を活用するバイメタリックアレーン類のフローマイクロ合成2021
- Author(s)
  川口倫子、芦刈洋祐、萬代恭子、相澤瑤子、永木愛一郎
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-20K15276
[Presentation] フローマイクロリアクターにより合成したバイメタリックアレーン類の化学選択的カップリング反応2021
- Author(s)
  芦刈洋祐、川口倫子、萬代恭子、相澤瑤子、永木愛一郎
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-20K15276

1. 永木愛一郎 (80452275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
2. 宮村浩之 (00548943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 信田尚毅 (20839972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 殿村修 (70402956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 松山清

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ashikari Yosuke 芦刈 洋祐

Yosuke Ashikari 芦刈 洋祐

Research Projects

Research Products

Co-Researchers

高速フロー法を活用したカルボカチオンの性質解明に立脚したグリコシル化反応の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Advanced utilization of multiple short-lived reactive species by application of flash flow electrolysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

糖化学の新展開のための非平衡カルボカチオン化学のネットワーク構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] Enabling Tools and Techniques for Organic Synthesis: A Practical Guide to Experimentation, Automation, and Computation2023

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 実験の自動化・自律化によるR&Dの効率化と運用方法 －AI、ロボット技術、ChatGPT、MI、ベイズ最適化、秘密計算など－2023

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] マイクロ・ナノ熱工学の進展2021

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] フロー合成、連続生産のプロセス設計、条件設定と応用事例2020

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] マイクロリアクター/フロー合成による反応条件を最適化した導入と目的に応じた実生産への適用2020

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Flowmicro In-Line Analysis-Driven Design of Reactions mediated by Unstable Intermediates: Flash Monitoring Approach2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Highly productive flow synthesis for lithiation, borylation, and/or Suzuki coupling reaction2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Elucidation of the kinetic stabilities of carbenoid species by integration of theoretical and experimental studies2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] One-flow operation via 4-bromopyridine enables flash synthesis of AChE inhibitor2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] External Flash Generation of Carbenoids Enables Monodeuteration of Dihalomethanes2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Continuous enantiomeric separation using water-oil-water segmented flow system2023

Author(s)

Ashikari Yosuke 芦刈洋祐

Yosuke Ashikari 芦刈洋祐

[Book] 実験の自動化・自律化によるR&Dの効率化と運用方法　－AI、ロボット技術、ChatGPT、MI、ベイズ最適化、秘密計算など－2023