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Okano Tokuju  岡野 徳壽

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岡野 徳壽  オカノ トクジュ

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Researcher Number 70886663
Other IDs
Affiliation (Current) 2025: 東京科学大学, 大学院医歯学総合研究科, 助教
Affiliation (based on the past Project Information) *help 2022 – 2024: 東京医科歯科大学, 大学院医歯学総合研究科, 助教
2020: 東京医科歯科大学, 大学院医歯学総合研究科, プロジェクト研究員
Review Section/Research Field
Principal Investigator
Basic Section 57020:Oral pathobiological science-related / 0907:Oral science and related fields
Except Principal Investigator
Medium-sized Section 49:Pathology, infection/immunology, and related fields
Keywords
Principal Investigator
STAT / インフラマソーム / 歯周炎 / Janus kinase / Peiodontitis / Inflammasome / 歯周炎関連細菌 / Porphyromonas gingivalis / inflammasome / JAK … More / ROS / HIF-1a / 多発性硬化症 / 口腔内細菌 / サイトカイン / 大腸癌 / フゾバクテリウム / 大腸炎 … More
Except Principal Investigator
シングルセルゲノム解析 / 西アフリカ / 感染伝播 / 比較ゲノム解析 / ブルーリ潰瘍 Less
  • Research Projects

    (4 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (3 People)
  •  P. gingivalis感染におけるJAK経路依存的炎症抑制メカニズムの解明Principal Investigator

    • Principal Investigator
      岡野 徳壽
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Isolation and analysis of Mycobacterium ulcerans associating with environment-human transmission using single-cell technology

    • Principal Investigator
      鈴木 敏彦
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Fund for the Promotion of Joint International Research (International Collaborative Research)
    • Review Section
      Medium-sized Section 49:Pathology, infection/immunology, and related fields
    • Research Institution
      Tokyo Medical and Dental University
  •  The mechanism of progression of Multiple sclerosis by periodontitis associated bacteriaPrincipal Investigator

    • Principal Investigator
      Okano Tokuju
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Tokyo Medical and Dental University
  •  口腔内細菌による自然免疫活性化が誘導する大腸癌増悪化機構の解明Principal Investigator

    • Principal Investigator
      岡野 徳壽
    • Project Period (FY)
      2020
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0907:Oral science and related fields
    • Research Institution
      Tokyo Medical and Dental University

All 2024 2023 2022

All Journal Article Presentation

  • [Journal Article] Inflammasome-triggered IL-18 controls skin inflammation in the progression of Buruli ulcer2023

    • Author(s)
      Suzuki Toshihiko、Boonyaleka Kotchakorn、Okano Tokuju、Iida Tamako、Yoshida Mitsunori、Fukano Hanako、Hoshino Yoshihiko、Iwakura Yoichiro、Ablordey Anthony S.、Ashida Hiroshi
    • Journal Title

      PLOS Pathogens

      Volume: 19 Issue: 11 Pages: e1011747-e1011747

    • DOI

      10.1371/journal.ppat.1011747

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23KK0138, KAKENHI-PROJECT-22K17011, KAKENHI-PROJECT-21H02728, KAKENHI-PROJECT-23K24127
  • [Journal Article] <i>Fusobacterium nucleatum</i> infection activates the noncanonical inflammasome and exacerbates inflammatory response in DSS‐induced colitis2023

    • Author(s)
      Boonyaleka Kotchakorn、Okano Tokuju、Iida Tamako、Leewananthawet Anongwee、Sasai Miwa、Yamamoto Masahiro、Ashida Hiroshi、Suzuki Toshihiko
    • Journal Title

      European Journal of Immunology

      Volume: 53 Issue: 11 Pages: 1-13

    • DOI

      10.1002/eji.202350455

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23KK0138, KAKENHI-PROJECT-22K17011, KAKENHI-PROJECT-21H02728, KAKENHI-PROJECT-23K24127
  • [Presentation] Tannerella forsythia induces inflammasome activation by triggering both NLRP3 and Caspase-4.2024

    • Author(s)
      Chenwei Hsu, Tokuju Okano, Toshihiko Suzuki.
    • Organizer
      第52回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K17011
  • [Presentation] Tannerella forsythia_induces inflammasome activation by triggering both NLRP3 and Caspase-42023

    • Author(s)
      Chenwei Hsu, Tokuju Okano, Toshihiko Suzuki
    • Organizer
      第52回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-23KK0138
  • [Presentation] Oral infection of P. gingivalis induces exacerbation of neurological manifestation in mice2023

    • Author(s)
      Tokuju Okano, Toshihiko Suzuki
    • Organizer
      第96回日本細菌学会総会
    • Data Source
      KAKENHI-PROJECT-22K17011
  • [Presentation] Tannerella forsythia induces inflammasome activation by triggering both NLRP3 and caspase-4_2023

    • Author(s)
      Chenwei Hsu, 岡野徳壽, 鈴木敏彦_
    • Organizer
      第88回口腔病学会学術集会_
    • Data Source
      KAKENHI-PROJECT-23KK0138
  • [Presentation] Porphyromnas gingivalis infection triggers enhancement of severity for EAE following inflammasome activation in macrophages.2022

    • Author(s)
      Tokuju Okano, Toshihiko Suzuki
    • Organizer
      第51回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K17011
  • 1.  鈴木 敏彦 (10292848)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 2.  星野 仁彦 (20569694)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  吉田 光範 (70772630)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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