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MIHARA TAIKI  三原 大輝

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Mihara Taiki  三原 大輝

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Researcher Number 70908326
Other IDs
Affiliation (Current) 2026: 国立医薬品食品衛生研究所, 毒性部, 主任研究官
Affiliation (based on the past Project Information) *help 2026: 東京大学, 大学院農学生命科学研究科(農学部), 助教
2021 – 2024: 東京大学, 大学院農学生命科学研究科(農学部), 助教
Review Section/Research Field
Principal Investigator
Basic Section 42020:Veterinary medical science-related / 0605:Veterinary medical science, animal science, and related fields
Except Principal Investigator
Basic Section 42020:Veterinary medical science-related
Keywords
Principal Investigator
肝臓線維化 / 線維芽細胞増殖因子23 / 肝臓 / 線維化 / 臓器連環 / 骨 / 骨異栄養症 / 臓器連関 / 骨粗鬆症 / マトリソーム / 肝硬変 … More
Except Principal Investigator
… More gastrointestine / smooth muscle / stromal cells / PDGFR alpha / ICC / 常在型マクロファージ / 平滑金細胞 / PDGFRα陽性間質前駆細胞 / カハール介在細胞 / 消化管 Less
  • Research Projects

    (5 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (1 People)
  •  代謝機能障害関連脂肪性肝疾患 (MASLD) における全身臓器連関の破綻メカニズムの解明Principal Investigator

    • Principal Investigator
      三原 大輝
    • Project Period (FY)
      2026 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      The University of Tokyo
  •  線維芽細胞増殖因子23に着目した肝硬変および続発する合併症の増悪メカニズムの解明Principal Investigator

    • Principal Investigator
      三原 大輝
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      The University of Tokyo
  •  Role of gastrointestinal stromal constituent cells in peristalsis and in the pathogenesis and repair of gastrointestinal diseases.

    • Principal Investigator
      堀 正敏
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      The University of Tokyo
  •  A Novel Pathogenic Mechanism of Osteoporosis; Liver-Bone Organ Crosstalk Mediated by Fibroblast Growth Factor 23Principal Investigator

    • Principal Investigator
      Mihara Taiki
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 42020:Veterinary medical science-related
    • Research Institution
      The University of Tokyo
  •  A novel therapeutic strategy for fibrosis targeting Fibroblast Growth Factor 23Principal Investigator

    • Principal Investigator
      Mihara Taiki
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0605:Veterinary medical science, animal science, and related fields
    • Research Institution
      The University of Tokyo

All 2025 2024 2023 2022

All Journal Article Presentation

  • [Journal Article] Pemigatinib suppresses liver fibrosis and subsequent osteodystrophy in mice2025

    • Author(s)
      Mihara Taiki、Tsuru Yoshiharu、Kurosawa Tamaki、Nonoshita Yuma、Yamakawa Yuki、Hori Masatoshi
    • Journal Title

      Hepatology Communications

      Volume: 9 Issue: 1

    • DOI

      10.1097/hc9.0000000000000610

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K15008
  • [Presentation] Liver-bone crosstalk mediated by fibroblast growth factor 23: Pemigatinib suppresses liver fibrosis and subsequent osteodystrophy2024

    • Author(s)
      Taiki Mihara, Yoshiharu Tsuru, Tamaki Kurosawa, Yuma Nonoshita, Yuki Yamakawa, Masatoshi Hori
    • Organizer
      The 1st Annual Meeting of the Japanese Cytokine Society
    • Data Source
      KAKENHI-PROJECT-22K15008
  • [Presentation] Pemigatinib suppresses liver fibrosis and subsequent osteoporosis2023

    • Author(s)
      Taiki Mihara, Yoshiharu Tsuru, Tamaki Kurosawa, Yuma Nonishita, Yuki Yamakawa, Masatoshi Hori
    • Organizer
      第97回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-22K15008
  • [Presentation] Novel osteoporosis mechanism: liver-bone crosstalk mediated by fibroblast growth factor 232022

    • Author(s)
      Taiki Mihara, Yoshiharu Tsuru, Masatoshi Hori
    • Organizer
      The Cytokines & ILC4
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15008
  • [Presentation] Novel osteoporosis mechanism: liver-bone crosstalk mediated by fibroblast growth factor 232022

    • Author(s)
      Taiki Mihara, Yoshiharu Tsuru, Masatoshi Hori
    • Organizer
      JSICR MMCB Joint Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15008
  • [Presentation] Novel osteoporosis mechanism: liver-bone crosstalk mediated by fibroblast growth factor 232022

    • Author(s)
      Taiki Mihara, Yoshiharu Tsuru, Masatoshi Hori
    • Organizer
      The Cytokines & ILC4
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K20613
  • [Presentation] Novel osteoporosis mechanism: liver-bone crosstalk mediated by fibroblast growth factor 232022

    • Author(s)
      Taiki Mihara, Yoshiharu Tsuru, Masatoshi Hori
    • Organizer
      JSICR MMCB Joint Symposium
    • Data Source
      KAKENHI-PROJECT-21K20613
  • 1.  堀 正敏 (70211547)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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