SAITO YURIKA 斉藤優梨花

… Alternative Names

斉藤優梨花サイトウユリカ

Less

Researcher Number	70970242
Affiliation (Current)	2026: 山形大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2026: 山形大学, 医学部, 助教 2023 – 2024: 山形大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related
Keywords	Principal Investigator MDM2 / p53 / がん

膠芽腫「幹」細胞のアキレス腱分子MDM2に着目した革新的p53活性化療法の構築Principal Investigator
- Principal Investigator
  
  斉藤優梨花
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Yamagata University
新規ライブセルタンパク間相互作用検出法を活用したグリオーマ細胞p53活性化薬の探索Principal Investigator
- Principal Investigator
  
  斉藤優梨花
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Yamagata University

All 2024 2023

All Journal Article Presentation

[Journal Article] CEP-1347 Boosts Chk2-Mediated p53 Activation by Ionizing Radiation to Inhibit the Growth of Malignant Brain Tumor Cells2024
- Author(s)
  Mitobe Yuta、Suzuki Shuhei、Nakamura Kazuki、Nakagawa-Saito Yurika、Takenouchi Senri、Togashi Keita、Sugai Asuka、Sonoda Yukihiko、Kitanaka Chifumi、Okada Masashi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 17 Pages: 9473-9473
- DOI
  10.3390/ijms25179473
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09202, KAKENHI-PROJECT-22K09250, KAKENHI-PROJECT-23K06689, KAKENHI-PROJECT-23K08492, KAKENHI-PROJECT-23K09020, KAKENHI-PROJECT-24K12234
[Journal Article] The MDM2?p53 Axis Represents a Therapeutic Vulnerability Unique to Glioma Stem Cells2024
- Author(s)
  Nakagawa-Saito Yurika、Mitobe Yuta、Togashi Keita、Suzuki Shuhei、Sugai Asuka、Takenouchi Senri、Nakamura Kazuki、Sonoda Yukihiko、Kitanaka Chifumi、Okada Masashi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 7 Pages: 3948-3948
- DOI
  10.3390/ijms25073948
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03040, KAKENHI-PROJECT-22K09202, KAKENHI-PROJECT-23K06689, KAKENHI-PROJECT-23K08492, KAKENHI-PROJECT-23K09020, KAKENHI-PROJECT-24K12234
[Journal Article] CEP-1347 Dually Targets MDM4 and PKC to Activate p53 and Inhibit the Growth of Uveal Melanoma Cells2023
- Author(s)
  Togashi Keita、Suzuki Shuhei、Mitobe Yuta、Nakagawa-Saito Yurika、Sugai Asuka、Takenouchi Senri、Sugimoto Masahiko、Kitanaka Chifumi、Okada Masashi
- Journal Title
  
  Cancers
  
  Volume: 16 Issue: 1 Pages: 118-118
- DOI
  10.3390/cancers16010118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09202, KAKENHI-PROJECT-23K06689, KAKENHI-PROJECT-23K08492, KAKENHI-PROJECT-23K09020, KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-21K16867
[Journal Article] Antagonizing MDM2 Overexpression Induced by MDM4 Inhibitor CEP-1347 Effectively Reactivates Wild-Type p53 in Malignant Brain Tumor Cells2023
- Author(s)
  Mitobe Yuta、Suzuki Shuhei、Nakagawa-Saito Yurika、Togashi Keita、Sugai Asuka、Sonoda Yukihiko、Kitanaka Chifumi、Okada Masashi
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 17 Pages: 4326-4326
- DOI
  10.3390/cancers15174326
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09202, KAKENHI-PROJECT-22K09250, KAKENHI-PROJECT-23K06689, KAKENHI-PROJECT-23K08492, KAKENHI-PROJECT-23K09020, KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-21K16867, KAKENHI-PROJECT-21H03040
[Journal Article] Domatinostat Targets the FOXM1?Survivin Axis to Reduce the Viability of Ovarian Cancer Cells Alone and in Combination with Chemotherapeutic Agents2023
- Author(s)
  Nakagawa-Saito Yurika、Mitobe Yuta、Suzuki Shuhei、Togashi Keita、Sugai Asuka、Kitanaka Chifumi、Okada Masashi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 13 Pages: 10817-10817
- DOI
  10.3390/ijms241310817
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09202, KAKENHI-PROJECT-23K06689, KAKENHI-PROJECT-23K08492, KAKENHI-PROJECT-23K09020, KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-21K16867
[Journal Article] The Novel MDM4 Inhibitor CEP-1347 Activates the p53 Pathway and Blocks Malignant Meningioma Growth In Vitro and In Vivo2023
- Author(s)
  Mitobe Yuta、Suzuki Shuhei、Nakagawa-Saito Yurika、Togashi Keita、Sugai Asuka、Sonoda Yukihiko、Kitanaka Chifumi、Okada Masashi
- Journal Title
  
  Biomedicines
  
  Volume: 11 Issue: 7 Pages: 1967-1967
- DOI
  10.3390/biomedicines11071967
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09202, KAKENHI-PROJECT-22K09250, KAKENHI-PROJECT-23K06689, KAKENHI-PROJECT-23K08492, KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-21K16867
[Presentation] CEP-1347 を用いた高悪性度髄膜腫に対する MDM4-p53 標的治療の有効性の検討2024
- Author(s)
  水戸部祐太,鈴木修平,斉藤優梨花,冨樫敬太 ,須貝明日香 ,園田順彦,北中千史,岡田雅司
- Organizer
  第24回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-23K08492
[Presentation] The Novel MDM4 Inhibitor CEP-1347 Activates the p53 Pathway and Blocks Malignant Meningioma Growth In Vitro and In Vivo2024
- Author(s)
  Mitobe Y, Suzuki S, Nakamura K, Nakagawa-Saito Y, Togashi K, Sugai A, Sonoda Y, Kitanaka C, Okada M
- Organizer
  The 19th Asian Society for Neuro-Oncology (ASNO)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08492
[Presentation] Novel MDM4 Inhibitor CEP-1347-based therapy for p53 wild-type malignant meningioma2024
- Author(s)
  Mitobe Y, Suzuki S, Nakamura K, Nakagawa-Saito Y, Togashi K, Sugai A, Sonoda Y, Kitanaka C, Okada M, Kinoshita M,Shibahara J,Ichimura K, Arakawa Y,Narita Y
- Organizer
  2024 SNO Annual Meeting and Education Day
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08492
[Presentation] p53野生型悪性脳腫瘍に対するCEP-1347を用いたMDM4/MDM2共標的治療戦略の有効性の検討2024
- Author(s)
  水戸部祐太,鈴木修平,斉藤優梨花,冨樫敬太 ,須貝明日香 ,園田順彦,北中千史,岡田雅司
- Organizer
  日本脳神経外科学会第83回学術総会
- Data Source
  KAKENHI-PROJECT-23K08492

1. 鈴木修平

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
2. 北中千史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAITO YURIKA 斉藤 優梨花

斉藤 優梨花 サイトウ ユリカ

Research Projects

Research Products

Co-Researchers

膠芽腫「幹」細胞のアキレス腱分子MDM2に着目した革新的p53活性化療法の構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

新規ライブセルタンパク間相互作用検出法を活用したグリオーマ細胞p53活性化薬の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] CEP-1347 Boosts Chk2-Mediated p53 Activation by Ionizing Radiation to Inhibit the Growth of Malignant Brain Tumor Cells2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The MDM2?p53 Axis Represents a Therapeutic Vulnerability Unique to Glioma Stem Cells2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CEP-1347 Dually Targets MDM4 and PKC to Activate p53 and Inhibit the Growth of Uveal Melanoma Cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antagonizing MDM2 Overexpression Induced by MDM4 Inhibitor CEP-1347 Effectively Reactivates Wild-Type p53 in Malignant Brain Tumor Cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Domatinostat Targets the FOXM1?Survivin Axis to Reduce the Viability of Ovarian Cancer Cells Alone and in Combination with Chemotherapeutic Agents2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Novel MDM4 Inhibitor CEP-1347 Activates the p53 Pathway and Blocks Malignant Meningioma Growth In Vitro and In Vivo2023

Author(s)

Journal Title

DOI

Data Source

[Presentation] CEP-1347 を用いた高悪性度髄膜腫に対する MDM4-p53 標的治療の有効性の検討2024

Author(s)

Organizer

Data Source

[Presentation] The Novel MDM4 Inhibitor CEP-1347 Activates the p53 Pathway and Blocks Malignant Meningioma Growth In Vitro and In Vivo2024

Author(s)

Organizer

Data Source

[Presentation] Novel MDM4 Inhibitor CEP-1347-based therapy for p53 wild-type malignant meningioma2024

Author(s)

Organizer

Data Source

[Presentation] p53野生型悪性脳腫瘍に対するCEP-1347を用いたMDM4/MDM2共標的治療戦略の有効性の検討2024

Author(s)

Organizer

Data Source

SAITO YURIKA 斉藤優梨花

斉藤優梨花サイトウユリカ