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YAMAGUCHI Yutaka  山口 豊

ORCIDConnect your ORCID iD *help
Researcher Number 80009448
External Links
Affiliation (based on the past Project Information) *help 1996: 千葉大学, 医学部
1986 – 1996: 千葉大学, 医学部, 教授
1990: 千葉大学, 医学部・肝癌研究施設・第一臨床研究部門, 教授
1990: Institute of Pulmonary Cancer Research, School of Medicine, Chiba University Su, 医学部肺癌研究施設第一臨床研究部門, 教授
1986: Department of Surgery, Institute of Pulmonary Cancer Research, 医学部, 教授
1985: 千葉大学, 医, 教授
Review Section/Research Field
Principal Investigator
Thoracic surgery
Except Principal Investigator
Thoracic surgery
Keywords
Principal Investigator
IL2 / モノクローナル抗体 / 肺癌 / unclear DNA / Biological nature / lymphokine-activated-killer cell / Immunotherapy of lung cancer / Surgery of lung cancer / monoclonal antibody / 細胞工学 … More / 外科療法 / LymphokineーActivatedーKiller細胞 / 肺癌細胞核DNA / 肺癌の生物学的性状 / 肺癌の免疫療法 / 肺癌の外科 / モノクロ-ナル抗体 / Airway dilatation / Nd-YAG laser / Concomitant immunity / LAK cells / Interleukin 2 / Anti-cancer drug in vitro sensitivity / Primary lung cancers / 所属リンパ節 / 腫瘍隨伴免疫 / 免疫療法 / 化学療法 / 肺非小細胞癌 / 集学的治療 / 気道開大 / Nd-YAGレーザー / 隨伴免疫 / LAK細胞 / Interlenkin2 / 制癌剤感受性試験 / 原発性肺癌 / Gene Therapy / Type IV Collagenase / Matrix Metalloproteinase / Genes associated with Metastasis / Metastasis / Lung Cancer / アンチセンスオリゴヌクレオチド / IV型コラゲナーゼ / アンチセンスDNA / 遺伝子治療 / 4型コラゲナーゼ / マトリックスメタロプロティナーゼ / 癌転移関連遺伝子 / 転移 … More
Except Principal Investigator
PCR-SSCP / 肺癌 / 免疫療法 / 転移 / cyclic GMP / 外科療法 / in vivo / 原発性肺癌 / in vitro / Ki-67 antigen / Immunohistochemistry / Ki-67抗原 / 免疫組織化学 / ヒト気管支上皮細胞 / 細胞外基質 / 人工気管 / LUNG CANCER / Cytotoxic activity / 血管内皮細胞 / 肺保存 / 細胞障害活性 / 同種肺移植 / 抗イディオタイプ抗体 / 肺癌培養細胞 / deepithelialized rat trachea / in vivo invasion assay / nude mouse / xenotransplantation / primary lung carcinoma / in vivo differentiation assay / Immunotherapy / Lung Cancer / LAK cell / 集学的治療 / LAK細胞 / LIMITED OPERATION / THYMIDINE KINASE / LAMININ / METASTASIS / 縮小手術 / ラミニン / チミジンキナ-ゼ / Experimental model / Cacinogenesis / Tracheobronchi / Human / invitro / invivo / 組織発生 / In vitro / In vivo / 発癌 / ヒト気管支上化細胞 / recurrence / Biological response modifiers / tumor concommitant immunity / Chemothrapy / Surgery / Primary lung cancer / 原発生肺癌 / 再発 / Biological Response Modifiers / 腫瘍随伴免疫 / 化学療法 / malignant pleurisy of lung cancer / gene therapy / NF2 gene / malignant methothelioma / NF2 / 胸膜中皮腫 / 肺癌癌性胸膜炎 / 免疫組織科学 / Ki-67抗体 / 肺癌・癌性胸膜炎 / 遺伝子治療モデル / NF2遺伝子 / 悪性胸膜中皮腫 / human / bronchial epithelial cell / coating / extracellular matrix / trachea / artifieial organ / 気道上皮細胞増生 / ヒト(人間) / 気管支上皮細胞 / コーティング / 気管 / 人工臓器 / CTL activity / acute rejection / superoxide anion / nitric oxide / endothelium / reperfusion after ischemia / lung transplantation / 活性酸素 / CTL活性 / CTL 活性 / 急性拒絶反応 / Superoxide anion / 一酸化窒素 / 虚血再灌流 / 肺移植 / Prognosis / Non-small cell lung cancer / myc gene / Apoptosis / p53 gene / p-53 / L-myc / Apotosis / Oncogene / Ki‐67抗原 / PCR‐SSCP / p53癌抑制 遺伝子 / 予後 / 非小細胞肺癌 / myc遺伝子 / アポトーシス / p53癌抑制遺伝子 / POROUS TYPE ARTIFICIAL TRACHEA / SERUM FREE MEDIUM / HUMAN BRONCHIAL EPITHELIAL CELL / COATING / EXTRACELLULAR MATERIALS / EXPLANT CULTURE / コラーゲン / 正常ヒト気管支上皮細胞 / マ-レックスメッシュ(Marlexmesh) / コーテイング剤 / explant culture / Porous type artificial trachea / マ-レックスメッシュ(Marlex mesh) / 無血清培地 / コーティング剤 / ANTIGEN SPECIFICITY / HUMORAL IMMUNITY / CELLULAR IMMUNITY / ADJIVANT THERAPY / IMMUNOTHERAPY / ANTI-IDIOTYPE ANTIBODY / SURGERY / モノクローナル抗体 / 腫瘍 / 免疫能 / リンパ管浸潤 / 血管浸潤 / 予後因子 / 肺転移 / 外科 / Cyclic GMP / Endothelial derived relaxing factor / Lung preservation / Rejection / Prostaglandin I2 / Lung transplantation / プリスタグランジンI_2 / cGMP / EDRF / Endothelial Derived Relaxing Factor / プロスタグランジンI_2 / 拒絶反応 / delayed type cutaneous hypersoustivity veactions / cellmediated immunit / hybridoma / anti-idiotype antibody / 合併療法 / 免疫賦汚 / モノクロ-ナル抗体 / 免疫賦活剤 / 遅延型皮膚反応 / 細胞融合法 / 特異的能動免疫療法 / 肺非小細胞癌 / 肺癌関連モノクローナル抗体 / 分化能 / 浸潤能 / deepithelialized / Adjuvant treatment / IL-2 / 細胞障害テスト / IL2 / OKT3 / 免疫療法(AIT) / Adjuvant療法 / LAK Cell / Adjurant療法 / ILー2 / Targeting therapy / Interleukin2(IL-2) / BRM療法 Less
  • Research Projects

    (17 results)
  • Co-Researchers

    (25 People)
  •  A study on the effectiveness of types of extracellular matrix to promote the growth of normal human bronchial epithelial cells in vitro or in vivo on artificial trachea made of Marlex mesh

    • Principal Investigator
      BABA Masayuki
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Chiba University
  •  Analysis of mutation in the neurofiblomatosis type 2 (NF2) gene in preneoplastic and neoplastic lesion of human pleura.

    • Principal Investigator
      SHIBA Mitsutoshi, 光永 伸一郎
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Chiba University
  •  Evaluation of endothelial function in cadaveric donor lung for lung allotransplantation

    • Principal Investigator
      SAITOH Yukio
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Chiba University
  •  DEVELOPMENT OF COATING MATERIAL FOR ARTIFICIAL TRACHER

    • Principal Investigator
      BABA Masayuki
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      CHIBA UNIVERSITY
  •  induction of Apoptosis by L-myc Gene and p53 Gene.

    • Principal Investigator
      SHIBA Mitsutoshi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Chiba University
  •  Study for Diagnosis and Treatment of Metastasis of Lung Cancer with Genetic Engineering.Principal Investigator

    • Principal Investigator
      YAMAGUCHI Yutaka
    • Project Period (FY)
      1993 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Thoracic surgery
    • Research Institution
      Chiba University School of Medicine
  •  Specific active immunotherapy with anti-idiotype monoclonal antibody in lung cancer patients

    • Principal Investigator
      FUJISAWA Takehiko
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Thoracic surgery
    • Research Institution
      CHIBA UNIVERSITY
  •  バイオテクノロジーの進歩に基づく肺癌のTargeting therapy

    • Principal Investigator
      小川 利隆
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Thoracic surgery
    • Research Institution
      Chiba University
  •  Anti-idiotype monoclonal antibody in the diagnosis and trectment of non-small cell carcinoma of the long

    • Principal Investigator
      FUJISAWA Takehiko
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Thoracic surgery
    • Research Institution
      Chiba University
  •  The study of disturbance on pulmonary endothelial cell during lung allograft rejection

    • Principal Investigator
      BABA Masayuki
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Chiba University
  •  Immunotherapy of lung cancer using biotechnological methods.

    • Principal Investigator
      KIMURA Hideki
    • Project Period (FY)
      1989 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Thoracic surgery
    • Research Institution
      Chiba University
  •  In vivo Invasion Assay and Enhancement of Differentiation of Low Passage Cultured Cells Derived from Human Non-Small Cell lung Carcinoma Using De-epithelialized Rat Tracheas Transplanted into Nude Mice.

    • Principal Investigator
      SHIBA Mitsutoshi, 山川 久美
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Chiba University
  •  Study on the metastatic capability of lung cancer in terms of cell biological properties.

    • Principal Investigator
      SHIBA Mitsutoshi, 由佐 俊和
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      Chiba University
  •  Diagnosis and Treatment of Lung Cancer with Cell Engineering TechniquePrincipal Investigator

    • Principal Investigator
      YAMAGUCHI Yutaka
    • Project Period (FY)
      1987 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Thoracic surgery
    • Research Institution
      Chiba University
  •  Development of an experimental model for human tracheobronchial carcinogenesis and a new method for early detection of tumor progression of malignant cell lines derived from human lung cancer using de-epithelialized rat tracheas xenotransplanted into nude mice.

    • Principal Investigator
      YAMAKAWA Hisami, 馬場 雅行
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Thoracic surgery
    • Research Institution
      School of Medicine, Chiba University
  •  Correlation between concommitant immunity and postoperative recurrence in primary resected lung cancers

    • Principal Investigator
      FUJISAWA Takehiko
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Thoracic surgery
    • Research Institution
      Chiba University School of Medicine
  •  Multi-modality treatment for primary non-small cell lungPrincipal Investigator

    • Principal Investigator
      YAMAGUCHI Yutaka
    • Project Period (FY)
      1984 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Thoracic surgery
    • Research Institution
      Chiba University School of Medicine
  • 1.  FUJISAWA Takehiko (80110328)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 0 results
  • 2.  SHIBA Mitsutoshi (20162620)
    # of Collaborated Projects: 14 results
    # of Collaborated Products: 0 results
  • 3.  BABA Masayuki (00143305)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 0 results
  • 4.  SUITO Yukio (60261905)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 5.  YAMAKAWA Hisami (80191211)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 6.  SAITOU Hiroaki (40186953)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 7.  KIMURA Hideki (10161572)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 8.  IIZASA Toshihiko (10272303)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 9.  MITSUNUGA Shinichiro (50272331)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 10.  YUSA Toshikazu (10182669)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  川野 裕 (40251160)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  田宮 敬久 (10251167)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  KADOYAMA Chikabumi (30152763)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 14.  FUKASAWA Toshio
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  藤野 道夫
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  YUSA Toshikazu (70230620)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  KOHNO Hiromasa (40272314)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  NOMOTO Yasushi (20218374)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  小川 利隆 (40241955)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  URABE Norikazu
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  SHIBUYA Kiyoshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  山本 直敬
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  柿沢 公孝
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  MITSUNAGA Shin-ichri
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  SAITO Hiroaki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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