• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

KOBAYASHI Toshio  小林 俊夫

ORCIDConnect your ORCID iD *help
Researcher Number 80020775
External Links
Affiliation (based on the past Project Information) *help 1997: SHINSHU UNIVERSITY HOSPITAL,ASSISTANT PROFESSOR, 医学部附属病院, 講師
1990 – 1997: Shinshu University School of Medicine First Department of Internal Medicine Assistant Professor, 医学部・附属病院, 講師
1995: Shinshu Univ., Assisstant professor, 医学部附属病院, 講師
1994: 信州大学, 講師
1994: SHINSHU UNIV.SCH.OF MED.ASSISTANT PROFESSOR, 医学部・付属病院, 講師 … More
1992 – 1993: 信州大学, 医学部, 講師
1986 – 1992: 信州大学, 医学部附属病院, 講師
1989: First Department of Internal Medicine, 医学部・附属病院第1内科, 講師
1989: 信州大学, 医学部附属病院第一内科, 講師
1988 – 1989: Dept.of Internal Med.Shinshu Univ., Assistant Professor, 医学部・第一内科学, 講師
1988: Shinshu University School of Medicine, Assistant Professor, 医学部付属病院, 講師
1988: 信州大学, 医学部第一内科, 講師
1987 – 1988: 信州大学, 医学部・附属病院, 講師
1986: 信大, 医学部, 講師
1986: Shinshu University School of Medicine Assistant Professor, 医学部, 講師 Less
Review Section/Research Field
Principal Investigator
Respiratory organ internal medicine
Except Principal Investigator
Respiratory organ internal medicine / 環境生理学(含体力医学・栄養生理学) / Circulatory organs internal medicine
Keywords
Principal Investigator
低酸素 / 肺水腫 / 高地 / HLA / 肺高血圧 / Hypoxia / Pulmonary edema / High altitude / 低酸素換気応答能 / 呼吸調節 … More / 低酸素性肺血管収縮反応 / 高地肺水腫 / Ventiration control / Brain edema / Hypobaria / 脳浮腫 / 低圧 / Exercise / Pulmonary hypertension / Pulmonary artery remodeling / Bronchoalveolar lavage / HLA analysis / Individual difference / High-altitude pulmonary edema / 右室肥大 / 肥満細胞 / 2,3-DPG / ANP / HLA-typing / 高山病 / 肺動脈圧 / 肺MAC症 / 運動負荷 / 肺動脈リモデリング / 気管支肺胞洗浄 / HLA解析 / 個体差 / endothelin / acute mountain sicknes / pulmonary edema / high altitude / oxygen transport / anaerobic threhold / maximal oxygen uptake / 高地適応 / 酸素摂取量 / 低酸素換気抑制 / 肺血管収縮反応 / 肺血流シンチグラム / 最大換気量 / エンドセリン / 急性高山病 / 酸素輸送 / 嫌気性代謝閾値 / 最大酸素摂取量 / Interleukin 8 / Interleukin 6 / Hypoxic ventilation response / Ventilatory control / 低酸素換気応答性 / インターロイキン8 / インターロイキン6 / Hypoxic ventilatory response / High altitude pulmonary edema / 低酸素肺血管収縮反応 / 超音波パルスドップラ-法 / 右心カテ-テル法 / 炭酸ガス換気応答 / 低酸素換気応答 … More
Except Principal Investigator
エンドトキシン / 緬羊 / エンドトキシン肺損傷 / 肺空気塞栓 / Sheep / 好中球 / Tumor necrosis factor / 覚醒時緬羊 / 高地肺水腫 / 好中球エラスターゼ / 摘出潅流肺 / 水分濾過係数 / 肺水腫 / 肺リンパ動態 / 肺高血圧 / High altitude / Endotoxin-induced lung injury / Perfluorocarbon / Ascaris-sensitized sheep / Airway hyperreactivity / Eosinophil / Bronchial asthma / Leukotriene B_4 / 気道反応性亢進 / 遅発型喘息反応 / 好酸球 / 気管支喘息 / Acute lung injury / エンドトキシン血症 / 肺リンパ瘻 / isolated perfused lungs / filtration coefficient / 摘出灌流肺 / Endotoxin / 肺循環動態 / 慢性肺リンパ瘻 / ARDS / Sleep apnea / Hypoxic ventilatory depression / Hypoxic ventilatory response / Acute mountain sickness / Respiratory control / High-altitude pulmonary edema / 低酸素性換気抑制 / 低酸素換気抑制 / 急性高山病 / Right ventricular hypertrophy / 肺循環 / 右心室肥大 / 高地順応 / SaO_2 / 一酸化窒素 / 肺微小血管透過性 / laser-Doppler method / lung lymph / Pulmonary circulation / db c-AMP / Eudotoxin / レーザードッペラー法 / db CAMP / レ-ザ-ドップラ-法 / 肺リンパ / dbcAMP / Lung Resistance / Dynamic Compliance / Pulmonary Function / Lung Injury / Awake Sheep / 換気力学 / 肺血管傷害 / TNF(tumor necrosis factor) / 肺機能(換気力学) / 肺粘性抵抗 / 動肺コンプライアンス / 肺機能 / 肺傷害 / Hypoxic Pulmonary vasoconstriction / Alveolar hypoxia / ピカ(ナキウサギ) / 右室肥大 / 肺血管収縮 / 低酸素 / blood viscosity / right ventricular hypertrophy / pulmonary artery pressure / pika / 赤血球の小型化 / ヘマトクリット / 高地適応動物 / ナキウサギ / Pika / Constantan / Thermocouples / Heat clearance curve / Tissue blood flow / 血流計 / 電解式組織血統計 / 電解式組織血流計 / コンスタンタン / 熱電対 / 熱拡散 / 組織血流 / Paraquat toxiciyt / Pulmonary microair embolism / Endotoxemia / Lung injury(increased permeability pulmonary edema) / Awake sheep / Chronic lung lymph fistula / 肺血管障害 / エンドトキシン肺傷害 / ロイコトリエン【B_4】 / 透過性亢進型肺水腫 / 白血球 / 血管透過性肺水腫 / パラコート / ARDS(adult respiratory distress syndrome) / パラコート中毒 / 肺微小空気塞栓 / 肺傷害(血管透過性肺水腫) / Denitrogenation / Decompression / Thromboxane <A_2> / Artificil climatic chanber / Pulmonary edema / 脱窒素 / 減圧 / トロンボキサン【A_2】 / 人工気象室 / 高地 / Proteinase / Interleukin / グルタチオン / 気道上皮液 / 蛋白分解酵素阻害剤 / VEGF,VPF / 蛋白分解酵素 / TNF / インターロイキン / Eosinophil cationic protein / Induced sputum / Lipid peroxidation / Antigen-induced asthmatic response / TAK-225 / U74006F / 遅発型の喘息反応 / ECP / 即時型喘息反応 / Eosinophic caticnic protein / 誘発喀痰 / アスカリス感作緬羊 / 脂質酸化 / 抗原誘発喘息反応 / Lung lymph flow / Liquid ventilation / Anesthetized sheep / 肺リンパ癌 / Perfluobrocarbon / 肺リンパ療 / 液体人工換気 / Cyelooxygluase / nitric oxide / prostaglandin / rabbit / interleukin-1beta / プロスタグランデイン / インターロイキン-1β / サイトカイン / 水分濾過保数 / インターロイキン1β / シクロオキシゲナーゼ / プロスタグランディン / 家兎 / インターロイキン 1β / Neutrophil elastase / Late asthmatic response / neutrophil / 炎症細胞 / 気道過敏性 / PAF / Thromboxane B_2 / アスカリス / アスカリス自然感作緬羊 / leukotrien B_4 / Sleep desaturation / 高炭酸ガス換気応答 / 運動 / 低酸素換気応答 / 睡眠時低酸素症 / 睡眠時周期性呼吸 / Elastase inhibitor / Elastase / Neutrophil / Air embolism / 特異的好中球エラスターゼ阻害剤 / 綿羊 / 好中球エラスターゼ阻害剤 / エラスターゼ阻害剤 / 急性肺損傷 / pulmonary edema / wet to dry lung weight ratio / pulmonary vascular permeability / polymorphonuclear leukocyte / leukotriene B4 / chemotactic factor / 肺温乾重量比 / ロイコトリエンB_4 / 肺湿乾重量比 / 肺微小血管壁透過性 / 多核白血球 / ロイコトリエンB4 / 白血球遊走因子 / Oxygen radicals / Lung injury / 動脈血ガス分析 / トロンボキサンA_2 / TNF肺損傷 / superoxide dismutase / Superoxide dismutase / 活性酸素 / 肺損傷 / High-altitude cerebral edema / 肺ガス多換 / 核磁気共鳴 / 高地脳浮腫 / 急性高山急 / 高地脳浮姿 / 睡眠時無呼吸 / 低酸素換気応答能 / 呼吸調節 / Pulmonary hypertension / Adaptation to high-altitude / Pulmonary Circulation / 酸素消費量 / 動脈血酸素飽和度 / 低酸素性肺血管収縮 / 脱順応 / チベット高地人 / 運動トレ-ニング / 低酸素性肺血管収縮(HPVC) / 多機白血球 / プロスタグランティン / 気管支上皮細胞 / 神経ペプチド / 気管支平滑筋 / 仔羊 / 肺毛細血管圧 / 反発係数 / 濾過係数 / 摘出還流肺 / 肺毛細血管透過性 Less
  • Research Projects

    (26 results)
  • Co-Researchers

    (24 People)
  •  Analysis of Genetic and Constitutional Factors for the Development of High-altitude Pulmonary EdemaPrincipal Investigator

    • Principal Investigator
      KUBO Keishi, 小林 俊夫
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Shinshu University
  •  重症敗血症に伴う臓器障害発生機序の解明とその治療法開発に関する実験的研究

    • Principal Investigator
      吉村 一彦
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Shinshu University
  •  THE ROLE OF INTERLEUKIN,TUMOR NECROSIS FACTOR-ALPHA AND PROTEINASES IN THE DEVELOPMENT OF ACUTE LUNG INJURY IN SHEEP

    • Principal Investigator
      KUBO Keishi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      SHINSHU UNIVERSITY
  •  EFFECTS OF EXERCISE AT HIGH ALTITUDE ON CARDIOPULMONARY FUNCTIONPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Toshio
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      SHINSHU UNIVERSITY SCHOOL OF MEDICINE
  •  THE ROLE OF INFLAMMATORY CELLS IN ANTIGENINDUCED ASTHMATIC RESPONSES AND AIRWAY HYPERRESPONSIVENESS.

    • Principal Investigator
      HONDA Takayuki, 藤本 圭作
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      SHINSHU UNIVERSITY SCHOOL OF MEDICINE
  •  Role of cytokine in increased permeability lung edema

    • Principal Investigator
      YOSHIMURA Kazuhiko
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Shinshu University
  •  USEFULNESS OF LIQUID VENTILATION BY PERFLUOROCARBON IN EXEPIMENTAL MODEL OF ACUTELUNG INJURY

    • Principal Investigator
      KUBO Keishi
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      SHINSHU UNIVERSITY
  •  気管支平滑筋収縮弛緩反応における気道上皮細胞の調節機構に関する実験的研究

    • Principal Investigator
      吉村 一彦
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Shinshu University
  •  THE PATHOGENESIS OF HIGH ALTITUDE PULMONARY EDEMA (HAPE)Principal Investigator

    • Principal Investigator
      TOSHIO Kobayashi
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      SHINSHU UNIVERSITY SCHOOL OF MEDICINE
  •  THE ROLE OF NEUTROPHIL AND EOSINOPHIL IN BRONCHIAL ASTHMA.

    • Principal Investigator
      FUJIMOTO Keisaku
    • Project Period (FY)
      1993 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      SHINSHU UNIVERSITY SCHOOL OF MEDICINE
  •  THE ROLE OF NEUTROPHIL, MACROPHAGE AND NEUTROPHIL ELASTASE IN THE DEVELOPMENT OF ACUTE LUNG INJURY

    • Principal Investigator
      KUBO Keishi
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      SHINSHU UNIVERSITY SCHOOL OF MEDICINE
  •  Abnormal control of breathing in high-altitude pulmonary edema (HAPE) ; effects of exercise, sleep, and hypoxic ventilatory response.

    • Principal Investigator
      SEKIGUCHI Morie
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      SHINSHU UNIVERSITY SCHOOL OF MEDICINE
  •  Effect of chemotactic factor on pulmonary vascular permeability

    • Principal Investigator
      YOSHIMURA Kazuhiko
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      SHINSHU UNIVERSITY SCHOOL OF MEDICINE
  •  肺毛細血管透過性評価についての総合的実験モデルの開発

    • Principal Investigator
      大久保 信一
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Shinshu University
  •  The role of abnormal control of breathing in the pathogenesis of high-altitude pulmonary edema

    • Principal Investigator
      MATSUZAWA Yukinori
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Shinshu University School of Medicine
  •  The Study to Clarify The Pathophysiology of Endotoxin-induced Lung Injury -Especially The Role of Tumor Necrosis Factor-

    • Principal Investigator
      KUBO Keishi
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Shinshu University School of Medicine
  •  Mechanisms of Adaptation to High-altitude on Pulmonary Circulation.

    • Principal Investigator
      SAKAI Akio
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      環境生理学(含体力医学・栄養生理学)
    • Research Institution
      Shinshu University
  •  Susceptibility of High Altitude PulmonaryPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Toshio
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Shinshu University School of Medicine
  •  THE PULMONARY FUNCTION IN LUNG INJURY INDUCED BY SEVERAL CUSES IN AWAKE SHEEP

    • Principal Investigator
      KUBO Keishi
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Shinshu University
  •  The Role of c-AMP and Ca ion on Awake Sheep Lung Injury

    • Principal Investigator
      UEDA Gou
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Department of Environmental Physiology, Shinshu University School of Medicine
  •  Pathophysiology of High Altitude pulmonary Edema in Japan and Qinghai, ChinaPrincipal Investigator

    • Principal Investigator
      KOBAYASHI Toshio
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Shinshu University School of Medicine
  •  Adaptation to high-altitude

    • Principal Investigator
      SAKAI Akio
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      環境生理学(含体力医学・栄養生理学)
    • Research Institution
      Shinshu University
  •  Effects of chronic alveolar hypoxia on pulmonary circulation

    • Principal Investigator
      HANDA Kenjiro, 草間 昌三
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Shinshu University School of Medicine
  •  THE ROLE OF VASOACTIVE SUBSTANCES IN INCREASED PERMEABILITY PULMONARY EDEMA

    • Principal Investigator
      HIRAYAMA Jiro, 吉村 一彦
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Shinshu University
  •  Development of tissue blood flowmeter employing heat clearance curve, and its clinical application.

    • Principal Investigator
      HANDA Kenjiro, 草間 昌三
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Shinshu University School of MEdicine
  •  Mechanism of pulmonary vascular injury in high altitude pulmonary edema.

    • Principal Investigator
      KUSAMA Shozo
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Shinshu University School of Medicine
  • 1.  KUBO Keishi (80143965)
    # of Collaborated Projects: 22 results
    # of Collaborated Products: 0 results
  • 2.  SAKAI Akio (70020758)
    # of Collaborated Projects: 17 results
    # of Collaborated Products: 0 results
  • 3.  YOSHIMURA Kazuhiko (70174985)
    # of Collaborated Projects: 12 results
    # of Collaborated Products: 0 results
  • 4.  UEDA Gou (10020702)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 5.  FUJIMOTO Keisaku (70242691)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 0 results
  • 6.  HONDA Takayuki (80238815)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 7.  HANDA Kenjiro (70020724)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 8.  KUSAMA Shozo (70020708)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 9.  FUKUSHIMA Masao (30173339)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 10.  MATSUZAWA Yukinori (40219423)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 11.  HIRAYAMA Jiro (90156696)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 12.  SEKIGUCHI Morie (70075232)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 13.  HOWMA Tatsuji (90020875)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 14.  KOIZUMI Tomonobu (20273097)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 15.  TAKEOKA Michiko (30197280)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 16.  SANO Kenji (50205994)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 17.  CHANG Sung Koh (80143981)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 18.  YANAGIDAIRA Yasunori (10020760)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  SHIBAMOTO Toshishige (90178921)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  HUJII Tadashige (50020780)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  大久保 信一 (80092865)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  臼田 信光 (30135123)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  斉藤 覚 (20175350)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  蜂谷 勤 (20303464)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi