SASSA Takeshi 佐々武史

… Alternative Names

佐々武史サツサタケシ

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Researcher Number	80023456
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Affiliation (Current)	2025: 山形大学, その他部局等(鶴岡), 名誉教授
Affiliation (based on the past Project Information) *help	2005 – 2006: Yamagata University, Faculty of Agriculture, Professor Emeritus, 農学部, 名誉教授 2005: 山形大学, 名誉教授 1999 – 2004: 山形大学, 農学部, 教授 1994 – 1995: 山形大学, 農学部, 教授 1989 – 1991: 山形大学, 農学部, 教授 1986 – 1987: 山形大学, 農学部, 教授 1986: 山形大, 農学部, 教授
Review Section/Research Field	Principal Investigator Bioproduction chemistry/Bioorganic chemistry / 製造化学・食品 / Bioproduction chemistry/Bioorganic chemistry Except Principal Investigator 製造化学・食品 / Living organism molecular science / Bioproduction chemistry/Bioorganic chemistry
Keywords	Principal Investigator 生合成 / フシコクシン / biosynthesis / Phomopsis amygdali / fusicoccin / 環化酵素遺伝子 / アフィジコリン / 発酵生産 / Phaeosphaeria sp.L487 / 白血病細胞 … More / 分化誘導 / コチレニン / Chloromonilinic acids / Moniliphenone / 4-chloropinselin / Bromomonilicin / Chloromonilicin / Rowth self-inhibitor / Phytopathogenic fungi / モニリフェノン / クロロモニリシンの生合成 / オウトウ灰星病菌 / オウトウ炭疽病菌 / ウスニン酸イソメトキシド / クロロモニリン酸 / モニリフエノン / 4-クロロピンセリン / ブロモモニリシン / クロロモニリシン / 自己生育阻害物質 / 植物病原糸状菌 / P450 oxygenase / cyclase / gene cluster / terpenoid / P450酸化酵素 / 環化酵素 / 遺伝子クラスター / テルペノイド / squarene / tetraterpene / biosynthetic intermediate / cyclization mechanism / terpene cyclase / diterpene / 非天然型トリテルペン / スクアレン-ホペン環化酵素 / アフィジコリンの環化機構 / テルペンテトリエン / ヤマブシタケ / テルペンテシン / サイアタジエン / エリナシン / フォマクチン / スクアレン / テトラテルペン / 生合成中間体 / 環化機構 / テルペン環化酵素 / ジテルペン / antitumor / cell differentiation / seed-germination promotion / cotylenin / semi-synthesis / fluorofusicoccin / 半合成テルペノイド / 発芽促進活性 / モモ枝折病菌 / 代謝変換 / フッ素化テルペノイド / 3-エピフシコクシンQ / コチレニンA / フシコクシン・Q / コチレノール / フロロフシコクシン / ABA / ガン細胞 / 3-エピフシコクシン / アブシジン酸 / 植物成長調節 / 抗腫瘍性 / 細胞分化誘導 / 発芽促進 / モモ枝折れ病菌 / 半合成 / フッ素化フシコクシン / terpene biosynthesis / aphidicolin / gibberellin / aphidicolan-8β-ol synthase / ent-kaurene synthase / Phoma betae / Gibberella fujikuroi / ジテルペン炭化水素の代謝変換 / 重水素標識フシコッカン / フシコッカン生合成中間体 / フシコクシン生合成経路 / ent-カウレン合成酵素遺伝子 / イネ馬鹿苗病菌 / コパリル二リン酸 / ジテルペン炭化水素 / クローニング / ジテルペン環化酵素 / テルペン生合成 / ジベレリン / アフィジコラ-16β-オール合成酵素 / エントーカウレン合成酵素 / テンサイ蛇眼病菌 / イネ馬鹿菌病菌 / 9> production / gibberellin A_<4 / gibberellin A_<82> / fungal gibberellin / gibberellin A_1 production / ジベレリンA_<20> / ジベレリンA_9 / ジベレリンA_1 / 小房子嚢菌 / カウレン合成酵素 / 9>生産 / ジベレリンA_<4 / ジベレリンA_<82> / カビジベレリン / ジベレリンA_1生産 / synthetic auxins / plant growth-inhibiting activity / propagation of Sugi calli / 2-(3-indolyl) propionic acid / syntheses of acremoauxins / acremoauxins / カルスの増殖 / 新オ-キシン物質 / インド-ルプロピオン酸 / スギカルス / 合成オ-キシン / 植物成長阻害 / 2ー(インド-ル)プロピオン酸 / スギカルスの増殖 / アクレモオ-キシンの合成 / アクレモオ-キシン / ヒト骨髄性白血病細胞 / 植物成長物質 / 新植物毒素 / 新ウスニン酸誘導体 / (+)-オキシマイコウスニン / (+)-イソマイコウスニン / (-)-マイコウスニン / カキ円星落葉病菌 … More Except Principal Investigator Alpha-(5, 7-Dichloroindole-)isobutyric acid / Floral bud formation / Indole--acetic acid / 5, 6-dichloroindole--acetic acid / Antiauxin / Auxin / 5,7ージフルオロインドールイソ酪酸 / 5,6ージフルオロインドールー3ー酢酸 / アンチオーキシン / オーキシン / 植物培養細胞 / ハロゲノインド-ル酢酸 / インド-ル酢酸 / 花芽形成物質 / 発根促進 / アンチオ-キシン / オ-キシン / 5,7ージクロルインド-ルイソ酪酸 / 5,6ージクロロインド-ル酢酸 / Phcnidium formation-inhibitory substances / Fruiting body-inducing substances / Sex pheromone of bacteria / Sporogenic substance in fungi / Reproduction-regulating substance in fungi / 分生子殻形成制御物質 / 形態形成 / メラニン合成 / 分生子殻形成阻害物質 / 発茸誘導物質 / 接合フェロモン / 細菌の性フェロモン / 胞子形成物質 / 生殖制御物質 / Chemogenomics / 14-3-3 Protein / Fusicoccin / Cotylenin / Diterpene Glycoside / Intracellular Signal Transduction / Differentiation-inducing Activity / Anti-cancer Activity / ケミカルジェノミクス / 分化誘導活性 / 有機低分子モデュレータ / ケモゲノミクス / 14-3-3タンパク質 / フシコクシン / コチレニン / ジテルペン配糖体 / 細胞内信号伝達 / 細胞分化誘導活性 / 抗癌活性 / 老化促進物質 / アコウ樹 / カスタステロン / トウモロコシ / 安息香酸 / 花成誘導物質 / アオウキクサ / アサガオ / 菌類 / ナフトール / メラニン / いもち病菌 / ジヒドロキシナフタレン / アロメラニン Less

Studies on production and improvement of terpenoids using biosynthetic gene cluster in fungi and plants.Principal Investigator
- Principal Investigator
  
  SASSA Takeshi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Yamagata University
植物生長物質コチレニン類による新たなヒト骨髄性白血病治療薬の創製基礎研究Principal Investigator
- Principal Investigator
  
  佐々武史
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Yamagata University
Chemogenomic approach for elucidation and control of intracellular signal transductions
- Principal Investigator
  
  KATO Nobuo
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  Osaka University
Scientific research on elucidation of terpene-cyclic reactions in the biosynthesis of bioactive microbial terpenoids.Principal Investigator
- Principal Investigator
  
  SASSA Takeshi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Yamagata University
Preparation/production and Utilization Researches of Terpenoidal Plant-growth Stimulants and Other Bioactive Substances with High Bioactivity.Principal Investigator
- Principal Investigator
  
  SASSA Takeshi
- Project Period (FY)
  2000 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Yamagata University
アロメラニンの構造研究
- Principal Investigator
  
  NUKINA Manabu
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Yamagata University
cDNA cloning and its development of diterpene cyclases forming its cyclic carbon skeleton from bioactive diterpene producing microorganismsPrincipal Investigator
- Principal Investigator
  
  SASSA Takeshi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Yamagata University
Construction of new gibberellin fermentation by a novel fungus phaeosphaeria sp. L487 and elucidation of its plant-like biosynthesis of gibberellin A_1Principal Investigator
- Principal Investigator
  
  SASSA Takeshi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Bioproduction chemistry/Bioorganic chemistry
- Research Institution
  Yamagata University
Synthesis of Fungal potent auxins, accremoauxins, and their applied study on initiation and propagation of frail calli of conifers.Principal Investigator
- Principal Investigator
  
  SASSA Takeshi
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  製造化学・食品
- Research Institution
  Yamagata University
植物病原糸状菌が生産する生物活性ウスニン酸誘導体に関する研究Principal Investigator
- Principal Investigator
  
  佐々武史
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  製造化学・食品
- Research Institution
  Yamagata University
Synthesis of New Indolic Plant Hormones and Their Application to Plant Tissue Cultures
- Principal Investigator
  
  MARUMO Shingo
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B).
- Research Field
  
  製造化学・食品
- Research Institution
  Nagoya University
新機能物質の探索
- Principal Investigator
  
  小清水弘一
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kyoto University
Sexual and Asexual Reproduction-regulating Substances of Microorganisms
- Principal Investigator
  
  MARUMO Shingo
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  製造化学・食品
- Research Institution
  Faculty of Agriculture, Nagoya University
Chemical Studies on Growth Self-inhibitors Produced by Phytopathogenic Fungi.Principal Investigator
- Principal Investigator
  
  SASSA Takeshi
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  製造化学・食品
- Research Institution
  Yamagata,University

All 2006 2005 2004

All Journal Article Patent

[Journal Article] Antitumor effect of cotylenin A plus interferon-alpha : possible therapeutic agents against ovary carcinoma2005
- Author(s)
  Y.Honma, T.Kasukabe, T.Yamori, N.Kato, T.Sassa
- Journal Title
  
  Gynecol.Oncol. 99(3)
  
  Pages: 680-688
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310150
[Journal Article] Effects of combined treatment with rapamycin and cotylenin A, a novel differentiation-inducing agent, on human breast carcinoma MCF-7 cells and xenogafts.2005
- Author(s)
  Kasukabe T., Okabe-Kado J., Kato N., Sassa T., Honma Y.
- Journal Title
  
  Breast Cancer Res. 7(6)
- Data Source
  KAKENHI-PROJECT-15310150
[Journal Article] Effects of combined treatment with rapamycin and cotylenin A, a novel differentiation-inducing agent, on human breast carcinoma MCF-7 cells and xenografts2005
- Author(s)
  T.Kasukabe, J.Okabe-Kado, N.Kato, T.Sassa, Y.Honma
- Journal Title
  
  Breast Cancer Res. 7(6)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15310150
[Journal Article] Effects of combined treatment with rapamycin and cotyienin A, a novel differentiation-inducing agent, on human breast carcinoma MCF-7 cells and xenografts2005
- Author(s)
  T.Kasukabe, J.Okabe-Kado, N.Kato, T.Sassa, Y.Honma
- Journal Title
  
  Breast Cancer Res. 7(6)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310150
[Journal Article] Antitumor effect of cotylenin A plus interferon-alpha : possible therapeutic agents against ovary carcinoma.2005
- Author(s)
  Honma Y., Kasukabe T., Yamori T., Kato N., Sassa T.
- Journal Title
  
  Gynecol Oncol. 99(3)
  
  Pages: 680-688
- Data Source
  KAKENHI-PROJECT-15310150
[Journal Article] Identification of (+)-Phyllocladene,(-)-Sandracopimaradiene, and (+)-Kaurene as New Fungal Metabolites from Fusicoccin-producing Phomopsis amygdali F6.2004
- Author(s)
  Kenmoku, H., Tanaka, K., Ogiyama, K., Kato, N., Sassa, T.
- Journal Title
  
  Biosci.Biotechnol.Biochem. 68(7)
  
  Pages: 1574-1577
- Data Source
  KAKENHI-PROJECT-15310150
[Journal Article] Erinacol (Cyatha-3,12-dien-14β-ol) and 11-O-Acetylcyathin A3, New Cyathane Metabolites from an Erinacine Q-Producing Hericium erinaceum.2004
- Author(s)
  Kenmoku, H., Tanaka, K., Okada, K., Kato, N., Sassa, T.
- Journal Title
  
  Biosci.Biotechnol.Biochem. 68(8)
  
  Pages: 1786-1789
- Data Source
  KAKENHI-PROJECT-15310150
[Journal Article] Novel Fusicoccins R and S, and Fusicoccin S Aglycone (Phomopsiol) from Phomopsis amygdali Niigata 2-A, and Their Seed Germination-stimulating Activity in the Presence of Abscisic Acid.2004
- Author(s)
  Tajima, N., Nukina, M., Kato, N., Sassa, T.
- Journal Title
  
  Biosci.Biotechnol.Biochem. 68(5)
  
  Pages: 1125-1130
- NAID
  10013144923
- Data Source
  KAKENHI-PROJECT-15310150
[Journal Article] Fusicocca-3(16),10(14)-diene, and β- and δ-Araneosenes, New Fusicoccin Biosynthesis-related Diterpene Hydrocarbons from Phomopsis amygdali.2004
- Author(s)
  Sassa, T., Kenmoku, H., Nakayama, K., Kato, N.
- Journal Title
  
  Biosci.Biotechnol.Biochem. 68(7)
  
  Pages: 1608-1610
- NAID
  10013520366
- Data Source
  KAKENHI-PROJECT-15310150
[Journal Article] Novel Fusicoccins R and S, and Fusicoccin S Aglycone (Phomopsiol) from Phomopsis amygdali Niigata 2-A, and Their Seed Germination-stimulating Activity in the Presence of Abscisic Acid2004
- Author(s)
  N.Tajima, M.Nukina, N.Kato, T.Sassa
- Journal Title
  
  Biosci.Biotechnol.Biochem. 68(5)
  
  Pages: 1125-1130
- NAID
  10013144923
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310150
[Journal Article] Erinacol (Cyatha-3,12-dien-14β-ol) and 11-O-Acetylcyathin A3, New Cyathane Metabolites from an Erinacine Q-Producing Hericium erinaceum2004
- Author(s)
  H.Kenmoku, K.Tanaka, K.Okada, N.Kato, T.Sassa
- Journal Title
  
  Biosci.Biotechnol.Biochem. 68(8)
  
  Pages: 1786-1789
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310150
[Journal Article] Identification of (+)-Phyllocladene, (-)-Sandracopimaradiene, and (+)-Kaurene as New Fungal Metabolites from Fusicoccin-producing Phomopsis amygdali F62004
- Author(s)
  H.Kenmoku, M.Tanaka, K.Ogiyama, N.Kato, T.Sassa
- Journal Title
  
  Biosci.Biotechnol.Biochem. 68(7)
  
  Pages: 1574-1577
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310150
[Journal Article] Fusicocca-3(16),10(14)-diene, and β- and δ-Araneosenes, New Fusicoccin Biosynthesis-related Diterpene Hydrocarbons from Phomopsis amygdali2004
- Author(s)
  T.Sassa, H.Kenmoku, K.Nakayama, N.Kato
- Journal Title
  
  Biosci.Biotechnol.Biochem. 68(7)
  
  Pages: 1608-1610
- NAID
  10013520366
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15310150
[Patent] 12-デオキシフシコクシン2006
- Inventor(s)
  加藤修雄, 本間良夫, 佐々武史, 他3名
- Industrial Property Rights Holder
  大阪大学, 島根大学
- Filing Date
  2006
- Data Source
  KAKENHI-PROJECT-15310150

1. KATO Nobuo (50150537)

# of Collaborated Projects: 5 results

# of Collaborated Products: 13 results
2. DAIRI Tohru (70264679)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. NUKINA Manabu (20113970)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. TOYOMASU Tomonobu (60272085)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. OIKAWA Hideaki (00185175)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. HOSHINO Tsutomu (30165542)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. MARUMO Shingo (30023394)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. OGIYAMA Koichi (60038239)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MITSUHASHI Wataru (50192761)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. IKEDA Michimasa (20007074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. YONEYAMA Koichi (00114174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. NITTA Hajime (20107098)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KAWANO Tomikazu (30283807)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TANAKA Junji (60155140)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
15. YAMANE Hisakazu (80090520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KAWAI Genshiro (30072309)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. SAKURAI Akira (10087562)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SUZUKI Akinori (90011907)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. TSUDA Mitsuya (10026578)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. NATSUME Masahiro (10201683)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. SAKAGAMI Youji (80107408)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 村山哲也 (20230013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 小清水弘一 (90026518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 山口五十麿 (00012013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 室伏旭 (00011916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 和田清俊 (80182971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 瀧本敦 (90026443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 片山正人 (90177410)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. FUTATSUYA Fumio

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SASSA Takeshi 佐々 武史

佐々 武史 サツサ タケシ

Research Projects

Research Products

Co-Researchers

Studies on production and improvement of terpenoids using biosynthetic gene cluster in fungi and plants.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

植物生長物質コチレニン類による新たなヒト骨髄性白血病治療薬の創製基礎研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Chemogenomic approach for elucidation and control of intracellular signal transductions

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Scientific research on elucidation of terpene-cyclic reactions in the biosynthesis of bioactive microbial terpenoids.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Preparation/production and Utilization Researches of Terpenoidal Plant-growth Stimulants and Other Bioactive Substances with High Bioactivity.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

アロメラニンの構造研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

cDNA cloning and its development of diterpene cyclases forming its cyclic carbon skeleton from bioactive diterpene producing microorganismsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Construction of new gibberellin fermentation by a novel fungus phaeosphaeria sp. L487 and elucidation of its plant-like biosynthesis of gibberellin A_1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Synthesis of Fungal potent auxins, accremoauxins, and their applied study on initiation and propagation of frail calli of conifers.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

植物病原糸状菌が生産する生物活性ウスニン酸誘導体に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Synthesis of New Indolic Plant Hormones and Their Application to Plant Tissue Cultures

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新機能物質の探索

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Sexual and Asexual Reproduction-regulating Substances of Microorganisms

Principal Investigator

Project Period (FY)

Research Category

SASSA Takeshi 佐々武史

佐々武史サツサタケシ