KANAIDE Hideo 金出英夫

… Alternative Names

金出英夫カナイデヒデオ

金井英夫カナイデヒデオ

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Researcher Number	80038851
Other IDs
Affiliation (Current)	2025: 国際医療福祉大学, 医療福祉学研究科, 教授
Affiliation (based on the past Project Information) *help	2000 – 2003: KYUSHU UNIVERSITY, Graduate School of Medical Sciences, Professor, 大学院・医学研究院, 教授 1999: 九州大学, 大学院・医学系研究科, 教授 1988 – 1998: Kyushu University, Faculty of Medicine, Professor, 医学部, 教授 1986 – 1987: Kyushu University, Faculty of Medicine, Lecture, 医学部, 講師 1986: 九大, 医学部, 講師
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine Except Principal Investigator Circulatory organs internal medicine
Keywords	Principal Investigator 血管平滑筋細胞 / 血管内皮細胞 / BCECF / fura-2 / 内皮細胞 / vascular smooth muscle cells / 血管平滑筋 / カルシウム / 心筋細胞 / 細胞質Ca濃度 … More / endothelial cells / カルシウムパラドックス / カルシウム過剰負荷 / ヒスタミン / 細胞シグナル伝達 / エンドセリン / Ca^<2+> signaling / トロンビン / Ca^<2+>シグナリング / ミオシン脱燐酸化酵素 / vascular smooth muscle / フラ-2 / 心筋障害 / フラ2 / イソプロテレノール / カフェイン / クイン2 / 細胞周期 / 細胞カルシウム濃度 / アシド-シス / NaーCa交換 / NADH蛍光 / Oxygen Radicals / Calcium Paradox / Alloprinol / Reperfusion Injury / Ischemic Myocardium / フリーラジカル / 虚血心筋 / NADH / 再潅流心筋障害 / Ca過剰負荷 / 活性酸素 / Caパラドックス / アロプリノール / 再灌流心筋障害 / 心筋虚血 / (pH)I / intracellular signalings / Na^+ / 〔pH〕i / HMG-CoA還元酵素 / [pH]i / myosin phosphatase / myosin phosphorylation / subarachnoid hemorrhage / thrombin / vasospasm / Ca^<2+> sensitization / Y27632 / Rho-Kinase / MYPT1 / TAT-Protein / 細胞質Ca^<2+>濃度 / ミオシン軽鎖燐酸化 / 細胞質[Ca^<++>]i / トロンビン受容体 / Protease-actvated receptors / ミオシン燐酸化 / クモ膜下出血 / 血管攣縮 / Ca^<2+>感受性 / regulation of vascular tonus / optical fibers / vascular sooth muscle cells / intracellular signaling network / 容量依存性性カルシウム流入 / タプシガルギン / 血管緊張調節 / 光学線維束 / intracellular signal transduction networks / cell cycle / calcium signaling / intimal thickening / coronary spasm / 細胞増殖 / 細胞情報伝達 / 冠血管形成術 / 細胞増殖接触抑制 / 血管管腔形成 / 細胞情報伝達網 / カルシウムシグナリング / 内膜肥厚 / 冠動脈攣縮 / cytosolic calcium concentration / measurements in vivo / Vascular endothelial cells / フラ-ス / 細胞質カルシウム / 生体計測 / 血管内皮 / calcium sensitivity / vasorelaxation / vasoconstriction / cell calcium / 血管〓縮 / cyclic AMP / エンドセリン受容体 / 細胞質カルシウム濃度 / 血管拡張 / カルシウム感受性 / 血管拡張薬 / 血管緊張 / 細胞カルシウム / Endothelium-derived relaxing factor(EDRF) / Endothelin / GTP-binding protein / Ethanol / Myocardial cells / Endothelial cells in situ / Vascular smooth muscle cells / Fura-2 / 細胞膜Ca^<++>濃度 / カプトリル / フラー2 / EDRF / G蛋白質 / 内皮由来弛緩因子(EDRF) / GTP結合蛋白質 / エタノール / cytosolic calcium / diltiazem / nitroglycerin / サイクリックGMP / 狭心症 / Ca特抗薬 / ATP感性Kチャネル / 細胞質Ca^<++>濃度 / 抗狭心症薬 / ジルチアゼム / ニトログリセリン / C-キナーゼ / ノルエピネフリン / 血管拘縮 / Protein kinase A / 血管リモデリング / GF10920X / CPI-17 / Protein inase C / Rho-kinase / NIH3T3細胞 / 血管モデル / 線維芽細胞 / 脱燐酸化反応 / ミオシンフォスファターゼ / 血管内膜 / カルシウムチャネル / 平滑筋細胞 / 百日咳毒素 / G蛋白 / 虚血・再潅流 / カプトプリル / アシドーシス / 心筋 / NaーH交換 / N_2ーH交換 / 細胞後Ca濃度 / オカダ酸 … More Except Principal Investigator 冠動脈攣縮 / セロトニン / 動脈硬化 / ARTERIOSCLEROSIS / INTRAMURAL HEMORRHAGE / MYOCARDIAL INFARCTION / 血管壁内出血 / 急性心筋梗塞 / WHHL / 突然死 / 血管内皮細胞 / 内皮細胞 / endothelium / serotonin / substance P / EDRF / WHHL RABBIT / STUNNED MYOCARDIUM / ANIMAL MODEL / rt-PA / THROMBOLYSIS / 冠動脈硬化 / 血栓性閉塞 / 組織プラスミノーゲンアクチベータ / 遺伝性高脂血症家兎 / 血栓溶解療法 / stunned myocardium / 再潅流障害 / 急性心筋梗塞発症 / 血栓溶解剤 / 心筋梗塞サイズ / 再灌流 / 組織プラスミノ-ゲンアクチベ-タ- / ENDOTHELIAL CELL / PTCA / SEROTONIN / CORONARY ARTERY SPASM / 中膜平滑筋 / X線照射 / 粥種内出血 / 冠動脈硬化とその進展 / 内皮細胞依存性血管弛緩 / 経皮経管形成術 / 心筋梗塞 / 流動脈攣縮 / forearm blood flow / aortic depressor nerve / sympathetic nerve activity / baroreceptors / ANP / 側枢室内投与 / 大動脈径 / 動脈圧受容器 / 反射性交感神経活動調節 / 心房性ナトリウム利尿ペプチド(ANP) / 心不全 / 前腕血流量 / 大動脈減圧神経 / 腎交感神経 / 圧受容器反射 / 心房性Na利尿ペプチド / Hyperlipifemia / WHHL rabbvit / Miniature Pig / Serotonin / Intramural hemorrhage / Myocardial infarction / Coronary artery spasm / 動物モデル / 狭心症 / 冠動脈〓縮 / 高脂血症 / ミニ豚 / 高コレステロール血症 / 急性心筋梗塞症 / vascular smooth muscle / caffeine / histamine / atherosclerosis / coronaryarteryspasm / カフェイン / 細胞内Ca^<++> / quin-2 / 内皮細胞依存性弛緩 / ヒスタミン / Atrial natriuretic peptide / Spontaneously hypertensive rat / High salt intake / Cardiopulmonary baroreflex / 心房筋伸展 / 心房性ナトリウム利尿ペブチド / 高血圧自然発生ラット / 高食塩食摂取 / 心肺圧受容体 / dysfunction / endothelium-derived relaxing factor / coronary artery spasm / 血管内皮細胞依存性弛緩 / Ca^<2+>チャネル / Ca^<2+>ーカイネティックス / 心筋虚血 / サブスタンスP / 内皮細胞依存性血管弛緩因子 / 冠攣縮 / substaucep / coronary spasm / endo the lium / couonay spasm Less

Research Projects
(29 results)
Co-Researchers
(19 People)

内皮・平滑筋・繊維芽細胞の三次元共培養による血管構築を摸した血管モデルの作製Principal Investigator
- Principal Investigator
  
  金出英夫
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
Molecular mechanisms of vasospasm : Intracellular signaling network underlying the Ca^<2+> of smooth muscle cells.Principal Investigator
- Principal Investigator
  
  KANAIDE Hideo
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
Development of a system for the continuous and simultaneous measurement of vascular intracellular signalings and metabolismPrincipal Investigator
- Principal Investigator
  
  KANAIDE Hideo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
血管内膜構築の制御における細胞シグナル伝達網の役割Principal Investigator
- Principal Investigator
  
  金出英夫
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
Development of the optical system for continuous and multi-factorial monitoring of the intracellular signaling network in endothelial and smooth muscle cells in vascular strips.Principal Investigator
- Principal Investigator
  
  KANAIDE Hideo
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
Studies on molecular cell biology of the inhibition of coronary vasoconstriction and intimal thickening.Principal Investigator
- Principal Investigator
  
  KANAIDE Hideo
- Project Period (FY)
  1995 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
心・血管系細胞における各種イオン動態制御の経時的変化とその異常Principal Investigator
- Principal Investigator
  
  金出英夫
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
TO DEVELOP A NEW SYSTEM TO CONTIMUOUSLY MONITOR THE FUNCTIONS AT THE CELLULAR AND MOLECULAR LEVELS OF THE VASCULAR ENDOTHELIAL AND SMOOTH MUSCLE CELLS IN VIVO.Principal Investigator
- Principal Investigator
  
  KANAIDE Hideo
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
心筋細胞の異常興奮と細胞内各種イオン濃度の相関Principal Investigator
- Principal Investigator
  
  金出英夫
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
血管機能の調節における内皮および平滑筋細胞情報伝達系の相互作用Principal Investigator
- Principal Investigator
  
  金井英夫
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
THE PATHOGENESIS OF AN INCREASE IN VASCULAR TONUS : THE DEVELOPMENT OF NEW VASODILATORS.Principal Investigator
- Principal Investigator
  
  KANAIDE Hideo
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
心筋細胞の異常興奮と細胞内各種イオン濃度の相関Principal Investigator
- Principal Investigator
  
  金出英夫
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
THE DEVELOPMENT AND THE CLINICAL APPLICATION OF AN OPTICAL SYSTEM FOR THE SIMULTANEOUS DETERMINATION OF METABOLIC AND FUNCTIONAL CHANGES IN THE HEART AND BLOOD VESSELS.Principal Investigator
- Principal Investigator
  
  KANAIDE Hideo
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
心筋細胞の異常興奮と細胞内各種イオン濃度の相関Principal Investigator
- Principal Investigator
  
  金出英夫
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Cellular and Molecular Mechanism Coronary Spasm
- Principal Investigator
  
  KOYANAGI Samon, 丸岡雄二
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
血管平滑筋細胞の細胞質カルシウム濃度調節機序Principal Investigator
- Principal Investigator
  
  金出英夫
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
CELLULAR BIOLOGY OF ANTIANGINAL AGENTS ; DEVELOPMENT AND EVALUATION OF NEW DRUGS.Principal Investigator
- Principal Investigator
  
  KANAIDE Hideo
- Project Period (FY)
  1989 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
心筋のカルシウム過剰負荷と細胞障害との相関に関する研究Principal Investigator
- Principal Investigator
  
  金出英夫
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
血管平滑筋細胞の細胞室カルシウム濃度調節機序Principal Investigator
- Principal Investigator
  
  金出英夫
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Pathophysiological Events Related to Coronary Spasm and Provocation of Intramural Hemorrhage at the Spastic Site.
- Principal Investigator
  
  NAKAMURA Motoomi
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
Development and assessment of animal models appropriate for evaluating thrombolytic agents for an early treatment of acute myocardial infarction
- Principal Investigator
  
  NAKAMURA Motoomi
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Research Institute of Angiocardiology and Cardiovascular Clinic Faculty of Medicine, Kyushu University
血管平滑筋細胞カルシウム動態連続観察法の確立とカルシウム制御異常発症機序の解明Principal Investigator
- Principal Investigator
  
  金出英夫
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kyushu University
心筋のカルシウム過剰負荷と細胞障害との相関に関する研究Principal Investigator
- Principal Investigator
  
  金出英夫
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
The role of atrial natriuretic peptide in control of circulation and body fluid in heart failure
- Principal Investigator
  
  TAKESHITA Akira
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
血管平滑筋細胞カルシウム動態連続観察法の確立とカルシウム制御異常発症機序の解明Principal Investigator
- Principal Investigator
  
  金出英夫
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kyushu University
Relationship between the evolution of coronary artery spasm and atherosclerosis and related basic studies on the mechanisms of coronary spasm
- Principal Investigator
  
  NAKAMURA Motoomi
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
Ischemic Reperfusion Myocardial Injury ; Its Mechanism and Prevention.Principal Investigator
- Principal Investigator
  
  KANAIDE Hideo
- Project Period (FY)
  1986 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University
Establishment of animal models with acuto myocardial infaroction and/or suuden death
- Principal Investigator
  
  NAKAMURA Motoomi
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  KYUSHU UNIVERSITY
Factors contributing to increases in circulating hypertensive peptides in genetic hypertension
- Principal Investigator
  
  TAKESHITA Akira
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kyushu University

1. NISHIMURA Junji (90237727)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
2. TAKESHITA Akira (30038814)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
3. KOBAYASHI Sei (80225515)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. HIRANO Katsuya (80291516)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
5. SUEISHI Katsuo (70108710)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
6. TOMOIKE Hitonobu (90112333)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
7. NAKAMURA Motoomi (60037322)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
8. SUNAGAWA Kenji (50163043)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
9. IMAIZUMI Tsutomu (60148947)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. KOYANAGI Samon (90128017)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 浦部由利 (10240904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. ABE Shimako (60192994)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YAMAMOTO Hiromichi (20166820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 丸岡雄二 (10190563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 稲生哲治 (10159965)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. AKAIKE Norio (30040182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 平祐二 (70179399)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 多治見司 (40136461)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 山元寅男 (80037324)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KANAIDE Hideo 金出 英夫

金出 英夫 カナイデ ヒデオ

金井 英夫 カナイデ ヒデオ

Research Projects

Co-Researchers

内皮・平滑筋・繊維芽細胞の三次元共培養による血管構築を摸した血管モデルの作製Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanisms of vasospasm : Intracellular signaling network underlying the Ca^<2+> of smooth muscle cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a system for the continuous and simultaneous measurement of vascular intracellular signalings and metabolismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

血管内膜構築の制御における細胞シグナル伝達網の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

Development of the optical system for continuous and multi-factorial monitoring of the intracellular signaling network in endothelial and smooth muscle cells in vascular strips.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on molecular cell biology of the inhibition of coronary vasoconstriction and intimal thickening.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

心・血管系細胞における各種イオン動態制御の経時的変化とその異常Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

TO DEVELOP A NEW SYSTEM TO CONTIMUOUSLY MONITOR THE FUNCTIONS AT THE CELLULAR AND MOLECULAR LEVELS OF THE VASCULAR ENDOTHELIAL AND SMOOTH MUSCLE CELLS IN VIVO.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

心筋細胞の異常興奮と細胞内各種イオン濃度の相関Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

血管機能の調節における内皮および平滑筋細胞情報伝達系の相互作用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

THE PATHOGENESIS OF AN INCREASE IN VASCULAR TONUS : THE DEVELOPMENT OF NEW VASODILATORS.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

心筋細胞の異常興奮と細胞内各種イオン濃度の相関Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

THE DEVELOPMENT AND THE CLINICAL APPLICATION OF AN OPTICAL SYSTEM FOR THE SIMULTANEOUS DETERMINATION OF METABOLIC AND FUNCTIONAL CHANGES IN THE HEART AND BLOOD VESSELS.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

心筋細胞の異常興奮と細胞内各種イオン濃度の相関Principal Investigator

Principal Investigator

KANAIDE Hideo 金出英夫

金出英夫カナイデヒデオ

金井英夫カナイデヒデオ