OBAYASHI Makio 小林槇雄

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KOBAYASH Makio 小林槇雄

小林槙雄コバヤシマキオ

KOBAYASHI Makio 小林槇雄

小林植雄コバヤシマキオ

KOBAYASHI Makio Associat 小林槇雄

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Researcher Number	80060086
Other IDs
Affiliation (based on the past Project Information) *help	2010: 東京女子医科大学, 医学部, 教授 1999 – 2005: 東京女子医科大学, 医学部, 教授 1991 – 1992: 東京女子医科大学, 医学部, 教授 1990: 東京女子医科大学, 医学部・第一病理, 教授 1989: 山梨医科大学, 医学部・第二病理学教室, 助教授 … More 1988 – 1989: 山梨医科大学, 医学部病理, 助教授 1987 – 1988: 山梨医科大学, 医学部, 助教授 1987: 山梨医科大学, 医学部・病理学, 助教授 Less
Review Section/Research Field	Principal Investigator Experimental pathology Except Principal Investigator Human pathology / Experimental pathology / Gastroenterology / General surgery
Keywords	Principal Investigator retinoblastoma / in situ hybridization / 網膜芽細胞腫 / cell differentiation / glutamate decarboxylase / extracellular matrix / 糖鎖構造 / 培養細胞 / 細胞芽細胞腫 / フィブロネクチン … More / SDS-PAGE / 分化誘導 / 神経伝達物質代謝酵素 / 細胞外マトリックス / southern blot analysis / ElA oncoprotein / RB gene / DNA analysis / adenovirus type 12 / Rhodopsin / in situハイブリダイゼ-ション / Rb遺伝子 / サザンブロット法 / EIA蛋白 / RB遺伝子 / DNA解析 / アデノウイルス12型 / 網膜ミューラー細胞 / 血液網膜関門 / ATPase / ポリアミン / 虚血性網膜浮腫 … More Except Principal Investigator スーパーオキシドジスムターゼ / 脂質過酸化 / 筋萎縮性側索硬化症 / 酸化的ストレス / superoxide dismutase / BrdU / 甲状腺 / Thyroid Gland / Receptor Dysfunction / Hormone Receptor / レセプター / ホルモン / Basedow病 / レセプター異常症 / ホルモン・レセプター / neuron / glia / inflammation / carbonyl stress / oxidative stress / transgenic mice / amyotrophic lateral sclerosis / グルタミン酸トランスポーター / 蛋白糖酸化 / PPARγ / 15d-PGJ_2 / プロスタグランジン / グリア反応 / 炎症反応 / ニューロン / グリア / 炎症 / カルボニルストレス / 酸化ストレス / トランスジェニックマウス / スーパーオキシドジムスターゼ / mutation / fulminant hepatitis / hepatitis B virus / 遺伝子変異 / B型肝炎ウィルス / 変異 / ウイルス変異 / 突然変異 / B型肝炎ウイルス / Progressive supranucelar palsy / Parkinson's disease / Multiple system atrophy / Amvotrophic lateral scerosis / Oxidative modification / Oxidative stress / Non-hereditary / Neurodegeneration / 核酸水酸化 / 蛋白糖化 / 過酸化物質 / 剖検材料 / イムノブロット法 / 免疫沈降法 / トランスジェーックマウス / 活性酸素傷害 / 進行性核上性麻痺 / パーキンソン病 / 多系統萎縮症 / 酸化的修飾 / 非遺伝性 / 神経変性疾患 / oxidative modification endoproducts / astrocyte / Fukuyama type / muscular dystrophy / Mn superoxide dismutase / CuZnsuperoxide disumtase / 8-hydroxy deoxyguanosine / 4-hydroxynonenala / advanced glycation endproducts / 福山型先天性筋ジストロフィー / superoxide disumutase / 酸化終末産物 / アストロサイト / 福山型 / 筋ジストロフィー / Nude mice / Cell culture / Oncogenes / Androgen receptor / Sex hormones / Carcinogenesis / Thyroid gland / ヌ-ドマウス移植 / 細胞培養 / 癌遺伝子 / アンドロゲン受容体 / 性ホルモン / 発癌 / HER 2遺伝子 / 組織Q-FISH / PR / ER / HER2遺伝子 / 正常乳腺 / 組織FISH / 予後診断 / テロメア / FISH / 遺伝子・染色体 / 乳癌 Less

Clinical application and prognostication in human breast cancer using tissue quantitative fluorescence in situ hybridization.
- Principal Investigator
  
  KAMMORI Makoto
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Nihon University
Identification of carbonyl stress in mice expressing a transgene for mutant superoxide dismutase-1
- Principal Investigator
  
  SHIBATA Noriyuki
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Women's Medical University
Characteristics of astrocytes in Fukuyama congenital muscular dystrophy.
- Principal Investigator
  
  YAMAMOTO Tomoko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tokyo Women's Medical University
Analyses of oxidative modification products in non-hereditary neurodegenerative diseases
- Principal Investigator
  
  SHIBATA Noriyuki
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Tokyo Woman's Medical University
Clinical significance of HBV mutation
- Principal Investigator
  
  HASEGAWA Kiyoshi
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Women's Medical University
Expression of RB gene and EIA oncoprotein in virus-induced retinal tumorPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Makio
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Women's Medical College
Molecular pathology of thyroid tumorigenesis
- Principal Investigator
  
  KAWAOI Akira
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Yamanashi Medical College
Morphology and differentiation of human retinoblastomaPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Makio
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Yamanashi Medical College
虚血性網膜浮腫におけるポリアミン代謝に関する研究Principal Investigator
- Principal Investigator
  
  小林槙雄
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  山梨医科大学
Study on the mechanisms of receptor dysfunction with special reference to Basedow's disease
- Principal Investigator
  
  KAWAOI Akira Professor
- Project Period (FY)
  1987 – 1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Yamanashi Medical College

All 2006 2005 2004

All Journal Article Book

[Book] Oxidative Stress Markers2005
- Author(s)
  N.Shibata, S.Toi, M.Kawaguchi, T.Yamamoto, M.Kobayashi
- Total Pages
  22296
- Publisher
  Gakkai-Shuppan Center
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570202
[Book] 酸化ストレスマーカー2005
- Author(s)
  柴田亮行, 小林槇雄, 他
- Total Pages
  8
- Publisher
  学会出版センター
- Data Source
  KAKENHI-PROJECT-14570202
[Book] 酸化ストレスマーカー2005
- Author(s)
  柴田亮行, 小林槇雄ほか
- Publisher
  学会出版センター
- Data Source
  KAKENHI-PROJECT-14570202
[Book] 酸化ストレスマーカー2005
- Author(s)
  柴田亮行, 遠井素乃, 川口素子, 山本智子, 小林槇雄
- Total Pages
  296
- Publisher
  学会出版センター
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570202
[Journal Article] Crotonaldehyde accumulates in glial cells of Alzheimer's disease brain2006
- Author(s)
  M.Kawaguchi, N.Shibata, S.Morikawa, M.Kobayashi, et al.
- Journal Title
  
  Acta Neuropathologica (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570202
[Journal Article] Protein-bound crotonaldehyde accumulates in the spinal cord of SOD1 mutation-associated familial ALS and its transgenic mouse model2006
- Author(s)
  N.Shibata, M.Kawaguchi, Y.Kato, M.Kobayashi, et al.
- Journal Title
  
  Neuropathology (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570202
[Journal Article] Crotonaldehyde accumulates in glial cells of Alzheimer's disease brain2006
- Author(s)
  M.Kawaguchi, N.Shibata, S.Morikawa, M.Kobayashi, et al.
- Journal Title
  
  Acta Neuropathologica (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570202
[Journal Article] Identification of a lipid peroxidation product as a potential trigger of the p53 pathway2006
- Author(s)
  T.Shibata, N Shibara, Y.Kawai, M.Kobayashi, K.Uchida, et al.
- Journal Title
  
  Journal of Biological Chemistry 281
  
  Pages: 1196-1204
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570202
[Journal Article] Identification of a lipid peroxidation product as a potential trigger of the p53 pathway2006
- Author(s)
  T.Shibata, N.Shibata, M.Kobayashi, K.Uchida, et al.
- Journal Title
  
  Journal of Biological Chemistry 281
  
  Pages: 1196-1204
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570202
[Journal Article] Protein-bound crotonaldehyde accumulates in the spinal cord of SOD1 mutation-associated familial ALS and its transgenic mouse model2006
- Author(s)
  N.Shibata, M.Kawaguchi, Y.Kato, M.Kobayashi, et al.
- Journal Title
  
  Neuropathology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570202
[Journal Article] Ultrastructural study of aggregates in the spinal cord of transgenic mice with a G93A mutant SOD1 gene2005
- Author(s)
  S.Sasaki, N.Shibata, M.Kobayashi, M.Iawata, et al.
- Journal Title
  
  Acta Neuropathologica 109
  
  Pages: 247-255
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570202
[Journal Article] PPARγ2005
- Author(s)
  柴田亮行, 小林槇雄ほか
- Journal Title
  
  Journal of Vascular Medicine 1(2)
  
  Pages: 196-203
- Data Source
  KAKENHI-PROJECT-14570202
[Journal Article] Ultranstructural study of aggregates in the spinal cord of transgenic mice with a G93A mutant SOD1 gene2005
- Author(s)
  S.Sasaki, N.Shibata, M.Kobayashi, M.Iwata, et al.
- Journal Title
  
  Acta Neuropathologica 109
  
  Pages: 247-255
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570202
[Journal Article] Glyoxal inactivates glutamate transporter-1 in cultured rat astrocytes2005
- Author(s)
  M.Kawaguchi, N.Shibata, S.Horiuchi, M.Kobayashi
- Journal Title
  
  Neuropathology 25
  
  Pages: 27-36
- NAID
  10017018660
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570202
[Journal Article] Accumulation of protein-bound 4-hydroxy-2-hexenal in spinal cords from patients with sporadic amyotrophic lateral sclerosis2004
- Author(s)
  N.Shibata, K.Uchida, M.Kawaguchi, M.Kobayashi, et al.
- Journal Title
  
  Brain Research 1019
  
  Pages: 170-177
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570202
[Journal Article] Accumulation of protein-bound 4-hydroxy-2-hexenal in spinal cords from patients with sporadic amyotrophic lateral sclerosis2004
- Author(s)
  N.Shibata, M.Kobayashi, et al.
- Journal Title
  
  Brain Research 1019
  
  Pages: 170-177
- Data Source
  KAKENHI-PROJECT-14570202
[Journal Article] Accumulation of protein-bound 4-hydroxy-2-hexenal in spinal cords fron patients with sporadic amyotrophic lateral sclerosis2004
- Author(s)
  N.Shibata, K.Uchida, M.Kawaguchi, M.Kobayashi, et al.
- Journal Title
  
  Brain Research 1019
  
  Pages: 170-177
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570202

1. TASAKA Kachio (40093265)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. SAWADA Tatsuo (90162544)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. KAWAOI Akira (30059224)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SHIBATA Noriyuki (90226176)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
5. KAMMORI Makoto (50292868)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KAMOTO Takahiro (70194397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SUZUKI Kouichi (20206478)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YAMAMOTO Tomoko (10239634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HASEGAWA Kiyoshi (30172886)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KATO Yoichiro (40233829)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. SATOH Takao Assistant Te (70162443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. USHIYAMA Hisashi Assista (60168680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 川真田明子 (80360155)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 鈴木留美 (90439852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 天野定雄 (80159459)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 坂本明子 (50386025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 内田直興 (30203540)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OBAYASHI Makio 小林 槇雄

KOBAYASH Makio 小林 槇雄

小林 槙雄 コバヤシ マキオ

KOBAYASHI Makio 小林 槇雄

小林 植雄 コバヤシ マキオ

KOBAYASHI Makio Associat 小林 槇雄

Research Projects

Research Products

Co-Researchers

Clinical application and prognostication in human breast cancer using tissue quantitative fluorescence in situ hybridization.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of carbonyl stress in mice expressing a transgene for mutant superoxide dismutase-1

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Characteristics of astrocytes in Fukuyama congenital muscular dystrophy.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analyses of oxidative modification products in non-hereditary neurodegenerative diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clinical significance of HBV mutation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Expression of RB gene and EIA oncoprotein in virus-induced retinal tumorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular pathology of thyroid tumorigenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Morphology and differentiation of human retinoblastomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

虚血性網膜浮腫におけるポリアミン代謝に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on the mechanisms of receptor dysfunction with special reference to Basedow's disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Oxidative Stress Markers2005

Author(s)

Total Pages

Publisher

Description

Data Source

[Book] 酸化ストレスマーカー2005

Author(s)

Total Pages

Publisher

Data Source

OBAYASHI Makio 小林槇雄

KOBAYASH Makio 小林槇雄

小林槙雄コバヤシマキオ

KOBAYASHI Makio 小林槇雄

小林植雄コバヤシマキオ

KOBAYASHI Makio Associat 小林槇雄