ITO Fumiaki 伊藤文昭

Researcher Number	80111764
Other IDs	https://orcid.org/0000-0002-4129-4899
Affiliation (based on the past Project Information) *help	2015 – 2018: サンスター株式会社ヘルスサイエンス研究所, オーラルケア/医薬品グループ, 特任研究員 2013: サンスター株式会社ヘルスサイエンス研究所, その他部局等, その他 1986 – 2012: 摂南大学, 薬学部, 教授 1992: 摂南大, 薬学部, 教授 1991: 慶應義塾大学, 薬学部, 教授 1986: 摂南大, 薬学部, 教授
Review Section/Research Field	Principal Investigator Biological pharmacy / Biological pharmacy Except Principal Investigator Biological pharmacy / Rehabilitation science/Welfare engineering / Circulatory organs internal medicine / General surgery
Keywords	Principal Investigator MNB / 上皮増殖因子 / DYRK1A / Down syndrome / リン酸化酵素 / ダウン症 / ErbB3 / 非小細胞肺がん / 抗がん剤 / チロシンキナーゼ阻害剤 … More / インテグリン / コラーゲン / カドヘリン / Na^+ / ErbB2 / Centrosome / Cell cycle / 中心体 / ヒト21番染色体 / Chromosome 21 / 多核細胞 / 抗癌剤 / EGF受容体 / 抗体医薬 / 上皮増殖因子受容体 / 細胞基質間接着 / グルココルチコイド / 細胞運動性 / 細胞間接着 / 肝細胞増殖因子 / Dibucaine / Lidocaine / Anesthetics / Transport of ions / Amiloride / Reconstitution / Liposome / H^+ antiporter / リポソーム / H^+アンチポーター / ジブカイン / リドカイン / 麻酔薬 / イオン輸送 / アミロライド / 再構成 / リポソ-ム / Na^+@H^+アンチポ-タ- / Non-small lung cancer / Molecular targeting drugs / Tyrosine kinase inhibitors / Anti-cancer drugs / Monoclonal antibody therapy / EGF receptor / EGF受容体の二量体化 / イレッサ / 非小細胞肺癌 / 分子標的薬 / Checkpoint at M phase / Kinase / M期チェックポイント / 細胞周期 / DYRX1A / Multinucleate cells / Dual-specificity protein kinase / Tubulin / Human chromosome 21 / Mnb / Dyrk1A / チュブリン / Multinucleation / Protein kinase / DYRK1A protein / Mnb遺伝子 / トリソミー / 核移行シグナル / 多角細胞 / タンパク質リン酸化酵素 / DYRK1Aタンパク質 / タンパク質リン酸酵素 / DTRK1Aタンパク質 / 21番染色体 / Cell adhesion / Collagen / Extracellular matrix / Cell migration / Integrin / Glucocorticoid / Epidermal growth factor / 接着斑 / 細胞接着 / 細胞外マトリックス / 細胞運動 / CELL-EXTRACELLULARMATRIX INTERACTION / CELL-CELL INTERACTION / CATENIN / CADHERIN / INTEGRIN / COLLAGEN / FOCAL ADHESION KINASE / EPIDERMAL GROWTH FACTOR / カテニン / フォーカルアドヒ-ジョンキナーゼ / Protein Kinase C / Carcinogenesis / Prostaglandin / Arachidonic acid / Cell motility / Cell growth / ゴ-ルデンハムスタ-細胞 / Cキナーゼ / がん化 / プロスタグランジン / アラキドン酸 / 細胞増殖 / リチウムイオンとリン酸化反応 / A-431細胞 / 細胞形態 / 細胞増殖因子 / 耐性細胞 / Bim / MKP-1 / アポトーシス / 抗がん剤耐性 / ゲフィチニブ / マイクロインジェクション / ジギトニン処理細胞 / 遺伝子導入 / MNB蛋白質 / DNA / 核移行 / 細胞集塊 / ラミニン / 胃癌細胞 / beta-カテニン … More Except Principal Investigator TNF / EGF / FGF / Cキナーゼ / トランスフォーメーション / TGF / Wnt / TGFβ / リポソーム / 増殖因子 / チロシン燐酸化 / iSTrap法 / BAP / dROMs / d-ROMs法 / 運動 / 活性酸素種 / 暑熱環境 / 酸化ストレス / 運動負荷 / 暑熱負荷 / Fe-ROMs法 / 酸化HDL / Mutation database / Gene mutation / Tumor / β-catenin / 遺伝子発現 / 細胞接着 / ガン / カドヘリン / GSK-3 / がん / Axin / バルプロ酸 / データベース / 遺伝子変異 / 癌 / β-カテニン / Signal Transduction / G-protein / Prostaglandin / Cellular Growth / Cytotoxicity / Tumor Necrosis Factor / 情報伝達機構 / Gタンパク質 / プロスタグランジン / 細胞増殖 / 細胞傷害 / 腫瘍壊死因子 / 増殖促進シグナル / V型コラーゲン / インスリン受容体キナーゼ / bFGF / DNA合成促進因子 / PI代謝回転 / チロシンリン酸化 / src / ras / myc / 受容体 / IGFーI / インスリン / ヘパリン / 細胞接着因子 / ビトロネクチン / フィブロネクチン / レセプター / IGF / ischemic preconditioning / ATP / 心筋細胞 / dvstrophin / 心筋梗塞 / 再潅流障害 / ミトコンドリア / ジストロフィン / 再潅流 / 虚血 / 心臓 / FGFレセプター / K-sam / インスリンレセプター / カルホスチンC / MAPキナーゼ / c-met / 肝細胞増殖因子 / 細網内皮系 / リポソ-ム / ドラッグデリバリ- / モノクロ-ナル抗体(B4G7) / 低アフィニティ-タイプ / イムノトキシン療法 / 上皮増殖因子受容体(EGFR) / リガンド結合型接合体 / 抗体結合型接合体 / 癌細胞 / 殺細胞効果 / 固相法 / 扁平上皮癌 / イムノジーン / イムノトキシン / 接合体 / 遺伝子導入 / ドラッグデリバリー・システム(DDS) / モノクローナル抗体(B4G7) / 上皮増殖因子レセプター(EGFR) / チロシンキナ-ゼ / インスリン受容体 / PDーECGF / cripto / cーmet / 転写因子 / GCF / オートクリン制御 Less

The relationship between reactive oxygen species and interleukin6 during exercise in heat stress
- Principal Investigator
  
  Ito Tomoyuki
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Wakayama Medical University
Anti-cancer antibody targeting epidermal growth factor receptor with constitutively active mutationsPrincipal Investigator
- Principal Investigator
  
  ITO Fumiaki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Sunstar Inc. Health Science Institute
  Setsunan University
Study on resistance of lung cancer cells to inhibitor of EGF receptor tyrosine kinasePrincipal Investigator
- Principal Investigator
  
  ITO Fumiaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Setsunan University
The role of dystrophin in the pathogenesis of myocardial reperfusion injury
- Principal Investigator
  
  OTANI Hajime
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kansai Medical University
Antitumor effects of monoclonal antibodies affecting dimerization between ErbB family membersPrincipal Investigator
- Principal Investigator
  
  ITO Fumiaki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Setsunan University
Cellular functions of MNB/DYRK1A gene cloned from "Down syndrome critical region"Principal Investigator
- Principal Investigator
  
  ITO Fumiaki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  SETSUNAN UNIVERSITY
FUNCTION OF THE HUMAN MNB/DYRK1A GENE ON THE "DOWN SYNDROME CRITICAL REGION" OF CHROMOSOME 21Principal Investigator
- Principal Investigator
  
  ITO Fumiaki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  SETSUNAN UNIVERSITY
Function, of MNB/DYRK1A gene cloned from "Down syndrome critical region" on chromosome 21.Principal Investigator
- Principal Investigator
  
  ITO Fumiaki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  SETSUNAN UNIVERSITY
DNAの核移行を制御する諸因子の解析Principal Investigator
- Principal Investigator
  
  伊藤文昭
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biological pharmacy
- Research Institution
  Setsunan University
FUNCTIONAL EVALUATION OF 0 -CATENIN GENE MUTATIONS IN TUMOR DEVELOPMENT : EFFECTS OF β-CATENIN MUTANTS ON CELL MOTILITY AND GENE EXPRESSION
- Principal Investigator
  
  TAKEUCHI Kenji, 芝本さゆみ
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  SETSUNAN UNIVERSITY
Antagonistic regulation of cell migration by epidermal growth factor and glucocorticoid.Principal Investigator
- Principal Investigator
  
  ITO Fumiaki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  SETSUNAN UNIVERSITY
グルココルチコイドと細胞増殖因子による細胞集塊の形成と分散の制御Principal Investigator
- Principal Investigator
  
  伊藤文昭
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Setsunan University
EFFECT OF EGF ON CELL-MATRIX INTERACTION AND TYROSINE PHOSPHORYLATION OF THE p125 FOCAL ADHESION KINASE IN HUMAN GASTRIC CARCINOMA CELLSPrincipal Investigator
- Principal Investigator
  
  ITO Fumiaki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  SETSUNAN UNIVERSITY
増殖因子による上皮細胞の細胞間接着と運動性の制御Principal Investigator
- Principal Investigator
  
  伊藤文昭
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Setsunan University
癌の増殖における増殖因子の相互作用とその分子機構
- Principal Investigator
  
  田原榮一
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hiroshima University
癌の増殖における増殖因子の相互作用とその分子機構
- Principal Investigator
  
  田原榮一
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Hiroshima University
増殖因子受容体を標的とする新しいDDSの開発と実用化の試み
- Principal Investigator
  
  清水信義
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Keio University
GROWTH RESPONSE OF GOLDEN HAMSTER EMBRYO CELLS WITH TRANSFORMED PHENOTYPES TO EXOGENOUS ARACHIDONIC ACIDPrincipal Investigator
- Principal Investigator
  
  ITO Fumiaki
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  SETSUNAN UNIVERSITY
Study of the Signal Transduction of and Cellular Response (Growth Stimulation and Cytotoxicity) to Tumor Necrosis Factor
- Principal Investigator
  
  OKU Naoto
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  UNIVERSITY OF SHIZUOKA
  Setsunan University
細胞増殖因子作用の分子機構とトランスフォーメーション
- Principal Investigator
  
  清水信義
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Keio University
細胞増殖因子作用の分子機構とトランスフォーメーション
- Principal Investigator
  
  清水信義
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Keio University
RECONSTITUTION OF THE Na^+/H^+ ANTIPORTER IN LIPOSOMESPrincipal Investigator
- Principal Investigator
  
  ITO Fumiaki
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  SETSUNAN UNIVERSITY
細胞増殖因子作用の分子機構とトランスフォーメーション
- Principal Investigator
  
  清水信義
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Keio University
細胞増殖因子の作用機構とトランスフォーメーションの研究
- Principal Investigator
  
  清水信義
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Keio University
細胞形態変化を指標とした細胞増殖因子のシグナル伝達機構の解明Principal Investigator
- Principal Investigator
  
  伊藤文昭
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Setsunan University

All 2017 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book

[Book] スタンダード薬学シリーズ４生物系薬学 IV. 演習編2011
- Author(s)
  青木隆、伊藤文昭
- Total Pages
  283
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PROJECT-23590098
[Journal Article] The application of a modified d-ROMs test for measurement of oxidative stress and oxidized high-density lipoprotein.2017
- Author(s)
  １）Ito F, Ito T, Suzuki C, Yahata T, Ikeda K, Hamaoka K.
- Journal Title
  
  Int J Mol Sci
  
  Volume: 18 Pages: 0-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K01383
[Journal Article] Ent-Kaurane Diterpenoids from Croton Tonkinensis Induce Apoptosis in Colorectal Cancer Cells through the Phosphorylation of JNK Mediated by Reactive Oxygen Species and Dual-Specificity JNK Kinase MKK42014
- Author(s)
  Phuong Thien Thuong, Nguyen Minh Khoi, Saho Ohta, Shinichiro Shiota, Hironori Kanta, Kenji Takeuchi and Fumiaki Ito
- Journal Title
  
  Anti-Cancer Agents in Medicinal Chemistry
  
  Volume: 14 Pages: 711-721
- Data Source
  KAKENHI-PROJECT-23590098
[Journal Article] EGFR T790M mutation as a possible target for immunotherapy; identification of HLA-A*0201-restricted T cell epitopes derived from the EGFR T790M mutation2013
- Author(s)
  Yamada T, Azuma K, Muta E, Kim J, Sugawara S, Zhang GL, Matsueda S, Kasama-Kawaguchi Y, Yamashita Y, Yamashita T, Nishio K, Itoh K, Hoshino T, Sasada T
- Journal Title
  
  PLoS ONE
  
  Volume: 8
- Data Source
  KAKENHI-PROJECT-23590098
[Journal Article] JNK-mediated FOXO expression plays a critical role in EGFR tyrosine kinase inhibitor-induced BIM expression and apoptosis2012
- Author(s)
  K.Takeuchi, A.H.Viet, K.Kawasaki, K.Nishio and F.Ito
- Journal Title
  
  J Cancer Therapy
  
  Volume: 3 Pages: 424-434
- Data Source
  KAKENHI-PROJECT-23590098
[Journal Article] Anaphase DNA bridges induced by lack of RecQ5 in Drosophila syncytial embryos2011
- Author(s)
  H. Sakurai, F.Ito
- Journal Title
  
  FEBS Letters
  
  Volume: 585 Pages: 1923-1928
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590098
[Journal Article] Receptor Tyrosine kinases and Targeted Cancer Therapeutics2011
- Author(s)
  K.Takeuchi and F.Ito
- Journal Title
  
  Biol.Pharm.Bull
  
  Volume: 34 Pages: 1774-1780
- NAID
  130001872594
- Data Source
  KAKENHI-PROJECT-23590098
[Journal Article] Target therapy for cancer: Anti-cancer drugs targeting growth-factor signaling molecules2011
- Author(s)
  K.Takeuchi, F.Ito
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 34 Pages: 1774-1820
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590098
[Journal Article] Dual regulation of hepatocyte apoptosis by reactive oxygen species : increases in transcriptional expression and decreases in proteosomal degradation of BimEL.2011
- Author(s)
  Y.Ishihara, K.Takeuchi, F.Ito, N.Shimamoto
- Journal Title
  
  J Cell Physiol. 226
  
  Pages: 1007-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590077
[Journal Article] Increased expression of c-Fos by extracellular signal-regulated kinase activation under sustained oxidative stress elicits BimEL upregulation and hepatocyte apoptosis2011
- Author(s)
  Y.Ishihara, F.Ito
- Journal Title
  
  FEBS J
  
  Volume: 278 Pages: 1873-1881
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590098
[Journal Article] Target therapy for cancer: Anti-cancer drugs targeting growth-factor signaling molecules2011
- Author(s)
  F.Ito
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 34 Pages: 1773-1773
- Data Source
  KAKENHI-PROJECT-23590098
[Journal Article] EGF receptor in relation to tumor development : molecular basis of responsiveness of cancer cells to EGFR-targeting tyrosine kinase inhibitors.2010
- Author(s)
  K.Takeuchi, F.Ito
- Journal Title
  
  FEBS J. 277
  
  Pages: 316-326
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590077
[Journal Article] High-level expression of Golsyn/Syntabulin in glandular epithelium and its role in the secretory process.2010
- Author(s)
  R.Oda, E.Funakoshi, K.Ozaki, K.Ogita, N.Shimizu, F.Ito
- Journal Title
  
  Journal of Epithelial Biology & Pharmacology 3
  
  Pages: 49-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590077
[Journal Article] Novel aspects of epidermal growth factor receptor in relation to tumor development.2010
- Author(s)
  F.Ito, K.Takeuchi
- Journal Title
  
  FEBS J. 277
  
  Pages: 300-300
- Data Source
  KAKENHI-PROJECT-20590077
[Journal Article] Novel aspects of epidermal growth factor receptor in relation to tumor development2010
- Author(s)
  F.Ito
- Journal Title
  
  FEBS J. 277
  
  Pages: 300-300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590077
[Journal Article] Loss of RecQ5 leads to spontaneous mitotic defects and chromosomal aberrations in Drosophila melanogaster.2009
- Author(s)
  M.Nakayam, S.Yamaguchi, Y.Sagisu, H.Sakurai, F.Ito, K.Kawasaki
- Journal Title
  
  DNA Repair 8
  
  Pages: 232-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590077
[Journal Article] Mitogen-activated protein kinase phosphatase-1-modulated JNK activation is critical for apoptosis induced by inhibitor of epidermal growth factor receptor-tyrosine kinase.2009
- Author(s)
  K.Takeuchi, T.Shin-Ya, K.Nishio, F.Ito
- Journal Title
  
  FEBS J. 276
  
  Pages: 1255-1265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590077
[Journal Article] EGFR mutation up-regulates EGR1 expression through the ERK pathway.2009
- Author(s)
  M.Maegawa, T.Arao, H.Yokote, K.Matsumoto, K.Kudo, K.Tanaka, H.Kaneda, Y.Fujita, F.Ito, K.Nishio
- Journal Title
  
  Anticancer Res. 29
  
  Pages: 1111-1117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590077
[Journal Article] Epidermal growth factor receptor lacking C-terminal autophosphorylation sites retains signal transduction and high sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor.2009
- Author(s)
  M.Maegawa, T.Arao, H.Yokote, K.Matsumoto, K.Kudo, K.Tanaka, H.Kaneda, Y.Fujita, F.Ito, K.Nishio
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 552-557
- NAID
  10025143753
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590077
[Journal Article] Growth stimulation of non-small cell lung cancer cell lines by antibody against epidermal growth factor receptor promoting formation of ErbB2/ErbB3 heterodimers2007
- Author(s)
  Mari Maegawa, Fumiaki Ito, 他5名
- Journal Title
  
  Mol Cancer Res 5(4)
  
  Pages: 393-401
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590088
[Journal Article] Growth stimulation of Non-small Cell Lung Cancer Cell Lines by Antibody against EGF Receptor Promoting Formation of ErbB2/ErbB3 Heterodimers2007
- Author(s)
  M.Maegawa, K.Takeuchi, E.Funakoshi, K.Kawasaki, K.Nishio, N.Shimizu, F.Ito
- Journal Title
  
  Molecular Cancer Research 5(4)
  
  Pages: 393-401
- Data Source
  KAKENHI-PROJECT-18590088
[Journal Article] 「研究成果報告書概要(欧文)」より2007
- Author(s)
  Mari Maegawa, Kenji Takeuchi, Eishi Funakoshi, Katsumi Kawasaki, Kazuto Nishio, Nobuyoshi Shimizu, Fumiaki Ito
- Journal Title
  
  Mol Cancer Res 5-4
  
  Pages: 393-401
- Data Source
  KAKENHI-PROJECT-18590088
[Journal Article] 「研究成果報告書概要(欧文)」より2006
- Author(s)
  Kenji Takeuchi, Yu-ichiro Motoda, Fumiaki Ito
- Journal Title
  
  FEBS Journal 273
  
  Pages: 3743-3755
- Data Source
  KAKENHI-PROJECT-18590088
[Presentation] Antitumor activity and target molecule of ent-kaurane diterpenoids in colorectal cancer cells2012
- Author(s)
  伊藤文昭
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-23590098
[Presentation] ゲフィチニブ感受性非小細胞肺がん細胞における上皮増殖因子受容体の細胞内経路2012
- Author(s)
  伊藤文昭
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-23590098
[Presentation] EGFRチロシンキナーゼ阻害剤によるアポトーシス促進型Bcl-2ファミリータンパク質Bimの転写レベルでの制御2011
- Author(s)
  竹内健治、Viet Anh Ho、西尾和人、伊藤文昭
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-20590077
[Presentation] EGFRチロシンキナーゼ阻害剤によるアポトーシス促進型Bcl-2ファミリータンパク質Bimの発現誘導機構2010
- Author(s)
  竹内健治、Viet Anh Ho、西尾和人、伊藤文昭
- Organizer
  第60回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-20590077
[Presentation] EGFRチロシンキナーゼ阻害剤によるアポトーシス促進型Bcl-2ファミリータンパク質Bimの発現誘導を介したアポトーシス誘導機構2010
- Author(s)
  竹内健治、Viet Anh Ho、西尾和人、伊藤文昭
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-30
- Data Source
  KAKENHI-PROJECT-20590077
[Presentation] 抗癌剤アドリアマイシンが誘導するアポトーシスに対する上皮増殖因子による抑制機構2010
- Author(s)
  車谷大樹、竹内健治、伊藤文昭
- Organizer
  第60回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-20590077
[Presentation] EGFRチロシンキナーゼ阻害剤によるアポトーシス促進型Bcl-2ファミリータンパク質Bimの発現誘導機構2010
- Author(s)
  竹内健治、Viet Anh Ho、西尾和人、伊藤文昭
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20590077
[Presentation] EGFRチロシンキナーゼ阻害剤AG1478によるアポトーシス誘導機構2010
- Author(s)
  永井絢子、竹内健治、Viet Anh Ho、西尾和人、伊藤文昭
- Organizer
  第60回日本薬学会近畿支部総会・大会
- Place of Presentation
  大阪
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-20590077
[Presentation] EGF受容体チロシンキナーゼ阻害剤に対する耐性獲得機構2009
- Author(s)
  新屋智寛、井本智大、濱宮由理、竹内健治、西尾和人、伊藤文昭
- Organizer
  日本薬学会第129年会
- Data Source
  KAKENHI-PROJECT-20590077
[Presentation] High-level expression of mitogen-activated protein kinase phosphatase-1 leads to resistance to inhibitor of EGF receptor tyrosine kinase2009
- Author(s)
  竹内健治、Viet Anh Ho、新屋智寛、井本智大、西尾和人、清水信義、伊藤文昭
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590077
[Presentation] EGFRチロシンキナーゼ阻害剤によるFasリガンド発現を介したアポトーシス誘導機構2009
- Author(s)
  竹内健治、永井絢子、西尾和人、伊藤文昭
- Organizer
  第82回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20590077
[Presentation] EGFR-ERK活性化を介する細胞死のシグナル伝達機構-酸化ストレスによるBimの発現、局在化制御-2009
- Author(s)
  石原康宏、関根雅也、竹内健治、伊藤文昭、嶋本典夫
- Organizer
  第62回日本酸化ストレス学会学術集会
- Data Source
  KAKENHI-PROJECT-20590077
[Presentation] Insulin prevents apoptosis induced by a specific inhibitor of EGFR kinase but not by adriamycin2008
- Author(s)
  Yu-suke Nakao, Kenji Takeuchi, Fumiaki Ito
- Organizer
  128th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  tyrosine Yokohama
- Year and Date
  2008-03-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590088
[Presentation] EGF受容体チロシンキナーゼ阻害剤に対する耐性獲得機構2008
- Author(s)
  新屋智寛、井本智大、濱宮由理、竹内健治、西尾和人、伊藤文昭
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学学会大会合同大会BMB2008
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-20590077
[Presentation] Acquired drug-resistance to inhibitors of EGF receptor (EGFR) tyrosine kinase in non-small cell lung cancer2008
- Author(s)
  新屋智寛、西尾和人、伊藤文昭, 他
- Organizer
  67th Annual Meeting of the Japanese Cancer Association
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20590077
[Presentation] Microarray analysis for wild type and delE746_750 type of EGFR introduced cells2008
- Author(s)
  前川麻里、伊藤文昭、西尾和人, 他
- Organizer
  67th Annual Meeting of the Japanese Cancer Association
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20590077
[Presentation] JNK activation is critical for epidermal growth factor receptor-tyrosine kinase inhibitor-induced apoptosis2008
- Author(s)
  竹内健治、新屋智寛、西尾和人、伊藤文昭
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学学会大会合同大会BMB2008
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-20590077
[Presentation] Mechanisms of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitor2008
- Author(s)
  Tomohiro Shinya, Mari Maegawa, Kazuto Nishio, Fumiaki Ito
- Organizer
  128th Annual Meeting of the Pharmaceutical Society of Japan
- Place of Presentation
  Yokohama
- Year and Date
  2008-03-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590088
[Presentation] 内因性酸化ストレスによる肝細胞アポトーシスはEGFR-ERK活性を介して起こる2008
- Author(s)
  石原康宏、竹内健治、伊藤文昭、嶋本典夫
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学学会大会合同大会BMB2008
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20590077
[Presentation] Protective action of insulin against EGFR tyrosine kinase inhibitor AG1478-induced apoptosis2007
- Author(s)
  Fumiaki Ito, Yoshimasa Matsuda, Kazuto Nishio, Kenji Takeuchi
- Organizer
  66th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Year and Date
  2007-10-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590088
[Presentation] A novel signaling pathway of deletional mutant EGFR2007
- Author(s)
  Mari Maegawa, HideyukiYokote, Kazuko Matsumoto, Kaoru Tanaka, Hiroyasu Kaneda, Yoshihiko Fujita, Marco De Verasco, Tokuzo Arao, Fumiaki Koizumi, Fumiaki Ito, Kazuto Nishio
- Organizer
  66th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Year and Date
  2007-10-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590088
[Presentation] インスリンによるEGF受容体チロシンキナーゼ阻害剤耐性獲得機構の解析2007
- Author(s)
  伊藤文昭
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590088
[Presentation] Bc1-2 family members as a target for the protective action of epidermal growth factor against adriamycin-induced apoptosis2007
- Author(s)
  Kenji Takeuchi, Yuuki Sato, Fumiaki Ito
- Organizer
  BMB2007
- Place of Presentation
  Yokohama
- Year and Date
  2007-12-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590088
[Presentation] Growth-stimulatory effect of anti-EGF receptor antibody upon two non-small lung cancer cell lines2006
- Author(s)
  伊藤文昭
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  京都
- Year and Date
  2006-06-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590088
[Presentation] Role of transcription factor AP1 in epidermal growth factor(EGF)-mediated protection against apoptosis induced by a DNA-damaging agent2006
- Author(s)
  Kenji Takeuchi, Yu-ichiro Motoda, Fumiaki Ito
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto
- Year and Date
  2006-06-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590088
[Presentation] Effects of ant-EGFR antibody on growth and downstream signaling of human non-small-cell lung cancer cell lines2006
- Author(s)
  Fumiaki Ito, Mari Maegawa, Kazuto Nishio, Nobuyoshi Shimizu
- Organizer
  65th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Year and Date
  2006-09-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590088
[Presentation] Protective action of insulin against apoptosis induced by EGFR tyrosine kinase inhibitor2006
- Author(s)
  Yoshimasa Matsuda, Kazufurni Uchida, Yukari Inoue, Kenji Takeuchi, Kazuto Nishio, Fumiaki Ito
- Organizer
  MBSJ Forum 2006
- Place of Presentation
  Kyoto
- Year and Date
  2006-09-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590088
[Presentation] Growth-stimulatory effect of anti-EGF receptor antibody upon two non-small lung cancer cell lines2006
- Author(s)
  Fumiaki Ito, Mari Maegawa, Kazuto Nishio, Nobuyoshi Shimizu
- Organizer
  20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto
- Year and Date
  2006-06-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590088
[Presentation] 抗EGF受容体抗体のヒト非小細胞肺がん株の増殖とシグナル伝達に与える影響2006
- Author(s)
  伊藤文昭
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2006-09-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590088
[Presentation] ダウン症原因遺伝子MNB/DYRK1Aの神経突起伸長促進作用とその機構の解析
- Author(s)
  寺嶋雅人、伊藤文昭
- Organizer
  第６１回日本薬学会近畿支部総会・大会
- Place of Presentation
  神戸学院大学
- Data Source
  KAKENHI-PROJECT-23590098
[Presentation] EGFRチロシンキナーゼ阻害剤耐性機構におけるBcl-2ファミリー分子発現誘導の役割
- Author(s)
  新崎さや乃、伊藤文昭
- Organizer
  第６１回日本薬学会近畿支部総会・大会
- Place of Presentation
  神戸学院大学
- Data Source
  KAKENHI-PROJECT-23590098
[Presentation] ショウジョウバエ初期胚を用いたDNAヘリカーゼRecQ5の機能解析－RecQ5の欠損が細胞周期の進行に与える影響－
- Author(s)
  東崇皓、伊藤文昭
- Organizer
  第６１回日本薬学会近畿支部総会・大会
- Place of Presentation
  神戸学院大学
- Data Source
  KAKENHI-PROJECT-23590098
[Presentation] EGFRチロシンキナーゼ阻害剤耐性機構におけるBcl-2ファミリー分子発現誘導の役割
- Author(s)
  新崎さや乃、伊藤文昭
- Organizer
  日本薬学会第１３２年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590098
[Presentation] RecQ5が持つ核移行シグナル領域の同定
- Author(s)
  桜井晴奈、伊藤文昭
- Organizer
  日本薬学会第１３２年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590098
[Presentation] EGFRチロシンキナーゼ阻害剤AG1478によるアポトーシス誘導機構
- Author(s)
  永井絢子、伊藤文昭
- Organizer
  日本薬学会第１３２年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590098
[Presentation] 変異型RecQ5が誘導する分化異常
- Author(s)
  川崎勝己、伊藤文昭
- Organizer
  日本薬学会第１３２年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590098
[Presentation] 二重鎖切断応答におけるRecQ5の役割
- Author(s)
  川崎勝己、伊藤文昭
- Organizer
  第８４回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590098
[Presentation] Antitumor activity and target molecules of ent-kaurane diterpenoids in colorectal cancer cells
- Author(s)
  伊藤文昭
- Organizer
  第７１回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590098
[Presentation] ショウジョウバエRecQ5に存在する核移行シグナルの解析
- Author(s)
  筒井彩夏、伊藤文昭
- Organizer
  第６１回日本薬学会近畿支部総会・大会
- Place of Presentation
  神戸学院大学
- Data Source
  KAKENHI-PROJECT-23590098
[Presentation] c-Metチロシンキナーゼ阻害剤PHA-665752によるアポトーシス誘導機構
- Author(s)
  小寺由香、伊藤文昭
- Organizer
  日本薬学会第１３２年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590098
[Presentation] ゲフィチニブ感受性非小細胞肺がん細胞における上皮増殖因子受容体の細胞内輸送経路
- Author(s)
  伊藤文昭
- Organizer
  日本薬学会第１３２年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590098
[Presentation] rDNA領域におけるRecQ5の働き
- Author(s)
  川崎勝己、伊藤文昭
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590098
[Presentation] EGFRチロシンキナーゼ阻害剤によるアポトーシス誘導へのBcl-2ファミリータンパク質Bimの関与
- Author(s)
  竹内健治、伊藤文昭
- Organizer
  第８４回日本生化学会大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590098
[Presentation] EGFRチロシンキナーゼ阻害剤高感受性ヒト非小細胞肺がん細胞から単離した耐性細胞の耐性獲得機構の解析
- Author(s)
  上原章兵、伊藤文昭
- Organizer
  第６１回日本薬学会近畿支部総会・大会
- Place of Presentation
  神戸学院大学
- Data Source
  KAKENHI-PROJECT-23590098
[Presentation] ショウジョウバエRecQ5の働き
- Author(s)
  桜井晴奈、伊藤文昭
- Organizer
  第６１回日本薬学会近畿支部総会・大会(招待講演)
- Place of Presentation
  神戸学院大学
- Data Source
  KAKENHI-PROJECT-23590098
[Presentation] ショウジョウバエの生体内におけるRecQ5の発現分布
- Author(s)
  桜井晴奈、伊藤文昭
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590098
[Presentation] ヒト非小細胞肺がんにお発現している変異型EGFZ受容体の細胞内輸送経路の解析
- Author(s)
  塩田真一朗、伊藤文昭
- Organizer
  第６１回日本薬学会近畿支部総会・大会
- Place of Presentation
  神戸学院大学
- Data Source
  KAKENHI-PROJECT-23590098

1. SHIBAMOTO Sayumi (80178920)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
2. 清水信義 (50162706)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
3. 河野通明 (00027335)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
4. OKU Naoto (10167322)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. FUNAKOSHI Eishi (70299030)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. 桑野信彦 (80037431)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. 西川克三 (10029960)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
8. 梅田誠 (70045996)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
9. HAYAKAWA Makio (30198824)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. HORI Takamitsu (00199522)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. NISHIO Kazuto (10208134)

# of Collaborated Projects: 3 results

# of Collaborated Products: 25 results
12. ITO Michiyasu (30201932)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. TAKEUCHI Kenji (30248067)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 田原榮一 (00033986)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. 春日雅人 (50161047)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. 馬渕博行 (50365508)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. OTANI Hajime (60168979)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SUZUKI Fumio (10019672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KUDOH Jun (80178003)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. Ito Tomoyuki (90305566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. 豊島秀男 (20197966)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 蒲生忍 (90122308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 加藤勝 (50233820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 川邊哲也 (60508034)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 木村正己

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

ITO Fumiaki 伊藤 文昭

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Anti-cancer antibody targeting epidermal growth factor receptor with constitutively active mutationsPrincipal Investigator

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Study on resistance of lung cancer cells to inhibitor of EGF receptor tyrosine kinasePrincipal Investigator

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Antitumor effects of monoclonal antibodies affecting dimerization between ErbB family membersPrincipal Investigator

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Cellular functions of MNB/DYRK1A gene cloned from "Down syndrome critical region"Principal Investigator

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FUNCTION OF THE HUMAN MNB/DYRK1A GENE ON THE "DOWN SYNDROME CRITICAL REGION" OF CHROMOSOME 21Principal Investigator

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Function, of MNB/DYRK1A gene cloned from "Down syndrome critical region" on chromosome 21.Principal Investigator

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DNAの核移行を制御する諸因子の解析Principal Investigator

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Antagonistic regulation of cell migration by epidermal growth factor and glucocorticoid.Principal Investigator

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グルココルチコイドと細胞増殖因子による細胞集塊の形成と分散の制御Principal Investigator

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EFFECT OF EGF ON CELL-MATRIX INTERACTION AND TYROSINE PHOSPHORYLATION OF THE p125 FOCAL ADHESION KINASE IN HUMAN GASTRIC CARCINOMA CELLSPrincipal Investigator

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増殖因子による上皮細胞の細胞間接着と運動性の制御Principal Investigator

ITO Fumiaki 伊藤文昭