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Fujiyoshi Yoshinori  藤吉 好則

… Alternative Names

FUJIYOSHI Yoshinori  藤吉 好則

藤吉 芳則  フジヨシ ヨシノリ

FUJIYOSHI Y.  藤吉 好則

Less
Researcher Number 80142298
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-8070-1493
External Links
Affiliation (Current) 2025: 東京科学大学, 総合研究院, 特別栄誉教授
Affiliation (based on the past Project Information) *help 2019 – 2024: 東京医科歯科大学, 高等研究院, 特別栄誉教授
2017 – 2018: 名古屋大学, 細胞生理学研究センター, 寄附研究部門教授
2012 – 2016: 名古屋大学, 細胞生理学研究センター, 特任教授
2007 – 2011: Kyoto University, 大学院・理学研究科, 教授
2008: Kyoto University, 大学院・理学研究科教授, 教授 … More
2006: 京都大学, 大学院理学研究科, 教授
2001 – 2005: 京都大学, 大学院・理学研究科, 教授
1996 – 1999: 京都大学, 大学院・理学研究科, 教授
1986: Res.Ass. Inst.Chem.Res.,Kyoto Univ., 化学研究所, 助手 Less
Review Section/Research Field
Principal Investigator
Biophysics / Biological Sciences / Basic Section 43020:Structural biochemistry-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
Except Principal Investigator
Biophysics / Structural biochemistry / 物理化学一般 / 広領域 / Biophysics / Neurochemistry/Neuropharmacology / Biological Sciences
Keywords
Principal Investigator
電子線結晶学 / 水チャネル / 膜タンパク質 / 単粒子解析法 / 構造生理学 / 単粒子解析 / アセチルコリン受容体 / 2次元結晶 / イオンチャネル / 構造生物学 … More / AQP-2 / CryoEM / FSEC / E3 ligase / Ubiquitin / Aquaporin-2 / クライオ電子顕微鏡法 / 膜タンパク質の生理機能 / 結晶学 / チャネル / クライオ電子顕微鏡 / Gating mechanism / Acetylcholine receptor / Water channel / Membrane proteins / Two-dimensional crystal / Single particle analysis / Cryo-electron microscope / Electron crystallography / PSDZip45(Homer1) / 代謝型グルタミン酸受容体 / 電圧感受性Na^+チャネル / アクアポリンー4 / Caveolin / エンドセリン受容体 / コネキシン / IP_3受容体 / ニコチン性アセチルコリン受容体 / アクアポリン-4 / ゲーティング / 膜蛋白質 / 極低温電子顕微鏡 / プロトンポンプ / 構造解析 / ナトリウムチャネル / H+,K+-ATPase / クローディン / ギャップ結合チャネル / プロテオミクス / シナプス / 細胞接着 / Gタンパク質共役型受容体 / 脳・神経 / 生理学 / 神経科学 / シグナル伝達 … More
Except Principal Investigator
タンパク質 / 電子線結晶学 / 二次元結晶 / 電子顕微鏡 / Bacteriorhodopsin / バクテリオロドプシン / アクアポリン-4 / 膜タンパク質 / アクアポリン / 水チャネル / 電子線結晶構造解析 / 水透過機構 / 極低温電子顕微鏡 / 構造生理学 / EELS / Graphite intercalation compound / Electron microscopy / Epitaxial growth / Structure / LB-film / Organic thin film / プラズモンロス / LB膜 / 電子線エネルギー損失スペクトル / グラファイト層間化合物 / トポタキシー / エピタキシー / 金属-有機物間相互作用 / 有機薄膜 / Protein / Refinement / Atomic Scattering Factor / Software / Electron Microscope / Electron Diffraction / Electron Crystallography / ソフトウエアー / 精密化 / 原子散乱因子 / ソフトウェアー / 電子線回折 / Module Structure / Structure-Function Relationship / Protein Structure / Phylogeny and Evolution / Symmetry of protein assembly / 形 / モジュール / グロビンファミリー / 対称性 / モデュール構造 / 構造-機能相関 / 蛋白質立体構造 / 系統・進化 / 蛋白質集合体の対称性 / Function / structure / signal / Photon / Rhodopsin / G-protein / Receptor / 先 / 機能 / 構造 / 情報 / 光 / ロドプシン / G蛋白質 / 受容体 / H+K+-ATPase / H+, K+-ATPase / 三次元構造 / 構造生物学 / H+,K+-ATPase / aquaporin-4 / 高分解能電子顕微鏡解析 / タンパク / 脳神経疾患 / シグナル伝達 / 神経科学 / PSD-95 / MAGUKファミリー / シナプス後肥厚 / シナプス可塑性 / PDZドメイン / 膜蛋白質 / シミュレーション / 電子線結晶解析 / クライオ技術 / 画像解析 / 分子動力学 / 大量発現 / 電子回折 / 立体構造解析 / AQP3 / AQP4 / クライオ電子顕微鏡 / バキュロウイルス / Sf9細胞 / 分子動力学シミュレーション / アクアポーリン Less
  • Research Projects

    (14 results)
  • Research Products

    (227 results)
  • Co-Researchers

    (42 People)
  •  ユビキチン化によるアクアポリン2の輸送制御機構の研究Principal Investigator

    • Principal Investigator
      藤吉 好則
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      Tokyo Medical and Dental University
  •  Structural physiology of channels based on development of cryo-electron microscopyPrincipal Investigator

    • Principal Investigator
      藤吉 好則
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
    • Research Institution
      Tokyo Medical and Dental University
  •  Studies in structural physiology of channelsPrincipal Investigator

    • Principal Investigator
      FUJIYOSHI Yoshinori
    • Project Period (FY)
      2015 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Biophysics
    • Research Institution
      Tokyo Medical and Dental University
      Nagoya University
  •  Structural and functional relationship of aqauporin-4 in brain

    • Principal Investigator
      Tani Kazutoshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      Nagoya University
  •  Structural and functional study of membrane proteins based on electron crystallographyPrincipal Investigator

    • Principal Investigator
      FUJIYOSHI Yoshinori
    • Project Period (FY)
      2010 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Biophysics
    • Research Institution
      Nagoya University
      Kyoto University
  •  Electron crystallographic analysis of two dimensional crystals of membrane proteins maintaining proton gradient

    • Principal Investigator
      TANI Kazutoshi
    • Project Period (FY)
      2010 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biophysics
    • Research Institution
      Nagoya University
      Kyoto University
  •  Regulation of synaptic transmission by the scaffolding protein PSD-95

    • Principal Investigator
      DOI Tomoko
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kyoto University
  •  Structural study of signal transduction through membrane proteins, channels and receptorsPrincipal Investigator

    • Principal Investigator
      FUJIYOSHI Yoshinori
    • Project Period (FY)
      2004 – 2008
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Biological Sciences
    • Research Institution
      Kyoto University
  •  水チャネルの選択性とその制御機構の解明

    • Principal Investigator
      MITSUOKA Kaoru
    • Project Period (FY)
      2001 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
      Kyoto University
  •  Structural study of membrane proteins (GPCR and channels) regulating signal transduction.Principal Investigator

    • Principal Investigator
      FUJIYOSHI Yoshinori
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Specially Promoted Research
    • Review Section
      Biological Sciences
    • Research Institution
      KYOTO UNIVERSITY
  •  Program System for Protein Electron Crystallography

    • Principal Investigator
      KIDERA Akinori
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biophysics
    • Research Institution
      KYOTO UNIVERSITY
  •  Analysis of Receptor G-protein coupling in the signal Transduction System of Atomic Resolution.

    • Principal Investigator
      SHICHIDA Yoshinori
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biophysics
    • Research Institution
      KYOTO UNIVERSITY
  •  Origin and phylogeny of symmetry structure of protein assemblies-requirement from function or phyloggenic consequence?

    • Principal Investigator
      MIMURO Mamoru
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      広領域
    • Research Institution
      YAMAGUCHI UNIVERSITY
      Okazaki National Research Institutes
  •  Structure and electronic state of thin organic films grown on metals

    • Principal Investigator
      UYEDA Natsu
    • Project Period (FY)
      1985 – 1986
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      物理化学一般
    • Research Institution
      Kyoto University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent Other

  • [Book] 現代生物科学入門3 構造機能生物学(第4章「膜タンパク質構造機能生物学」)2011

    • Author(s)
      藤吉好則
    • Publisher
      岩波書店
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Book] 現代生物科学入門 構造機能生物学2011

    • Author(s)
      藤吉好則, 中川敦史, 前田雄一郎, 小田俊郎, 嶋田一夫, 西田紀貴, 谷一寿, 加藤博章
    • Publisher
      岩波書店
    • Data Source
      KAKENHI-PROJECT-22770147
  • [Book] 構造生物学(現代生物科学入門第3巻)2011

    • Author(s)
      藤吉好則
    • Total Pages
      220
    • Publisher
      岩波書店
    • Data Source
      KAKENHI-PROJECT-22770147
  • [Book] STRUCTURE AND INHIBITOR OF WATER CHANNEL IN BRAIN., "Water : The Forgotten Biological Molecule", D. L. Bihan and H. Fukuyama ed2011

    • Author(s)
      Y. Tanimura, K. Tani, H. Suzuki, K. Nishikawa, A. Kamegawa, Y. Hiroaki, Y. Fujiyoshi
    • Publisher
      Pan Stanford Publishing
    • Data Source
      KAKENHI-PROJECT-22770147
  • [Book] The AQP structure and functional implications. Handb. Exp. Pharmacol., 1902009

    • Author(s)
      T. Walz, Y. Fujiyoshi and A. Engel
    • Publisher
      Springer-Verlag.
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Book] 膜タンパク質のナノバイオロジー チャネルの分子構造を機能 ナノバイオロジー ナノテクノロジーによる生命科学 第4章2004

    • Author(s)
      光岡薫, 藤吉好則
    • Publisher
      共立出版
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Journal Article] The structural basis of divalent cation block in a tetrameric prokaryotic sodium channel2023

    • Author(s)
      Irie Katsumasa、Oda Yoshinori、Sumikama Takashi、Oshima Atsunori、Fujiyoshi Yoshinori
    • Journal Title

      Nature Communications

      Volume: 14 Issue: 1 Pages: 4236-4236

    • DOI

      10.1038/s41467-023-39987-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H00451
  • [Journal Article] Recognition Mechanism of a Novel Gabapentinoid Drug, Mirogabalin, for Recombinant Human α2δ1, a Voltage-Gated Calcium Channel Subunit2023

    • Author(s)
      Kozai Daisuke、Numoto Nobutaka、Nishikawa Kouki、Kamegawa Akiko、Kawasaki Shohei、Hiroaki Yoko、Irie Katsumasa、Oshima Atsunori、Hanzawa Hiroyuki、Shimada Kousei、Kitano Yutaka、Fujiyoshi Yoshinori
    • Journal Title

      Journal of Molecular Biology

      Volume: 435 Issue: 10 Pages: 168049-168049

    • DOI

      10.1016/j.jmb.2023.168049

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H00451, KAKENHI-PROJECT-20K09193, KAKENHI-PROJECT-19H03165
  • [Journal Article] Dynamically regulated two-site interaction of viral RNA to capture host translation initiation factor2023

    • Author(s)
      Imai Shunsuke、Suzuki Hiroshi、Fujiyoshi Yoshinori、Shimada Ichio
    • Journal Title

      Nature Communications

      Volume: 14 Issue: 1 Pages: 4977-4977

    • DOI

      10.1038/s41467-023-40582-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H00451
  • [Journal Article] Structural basis of hydroxycarboxylic acid receptor signaling mechanisms through ligand binding2023

    • Author(s)
      S. Suzuki, K. Tanaka, K. Nishikawa, H. Suzuki, A. Oshima, Y. Fujiyoshi
    • Journal Title

      Nat. Commun.

      Volume: 14 Issue: 1 Pages: 5899-5899

    • DOI

      10.1038/s41467-023-41650-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K19215, KAKENHI-PROJECT-20H00451
  • [Journal Article] Structural analysis of the water channel AQP2 by single-particle cryo-EM2023

    • Author(s)
      Kamegawa Akiko、Suzuki Shota、Suzuki Hiroshi、Nishikawa Kouki、Numoto Nobutaka、Fujiyoshi Yoshinori
    • Journal Title

      Journal of Structural Biology

      Volume: 215 Issue: 3 Pages: 107984-107984

    • DOI

      10.1016/j.jsb.2023.107984

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08304, KAKENHI-PROJECT-20H00451
  • [Journal Article] On the reduction in the effects of radiation damage to two-dimensional crystals of organic and biological molecules at liquid-helium temperature2022

    • Author(s)
      Naydenova Katerina、Kamegawa Akiko、Peet Mathew J.、Henderson Richard、Fujiyoshi Yoshinori、Russo Christopher J.
    • Journal Title

      Ultramicroscopy

      Volume: 237 Pages: 113512-113512

    • DOI

      10.1016/j.ultramic.2022.113512

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00451
  • [Journal Article] Structures of human pannexin-1 in nanodiscs reveal gating mediated by dynamic movement of the N terminus and phospholipids2022

    • Author(s)
      Kuzuya Maki、Hirano Hidemi、Hayashida Kenichi、Watanabe Masakatsu、Kobayashi Kazumi、Terada Tohru、Mahmood Md. Iqbal、Tama Florence、Tani Kazutoshi、Fujiyoshi Yoshinori、Oshima Atsunori
    • Journal Title

      Science Signaling

      Volume: 15 Issue: 720

    • DOI

      10.1126/scisignal.abg6941

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03683, KAKENHI-PROJECT-19H03165, KAKENHI-PROJECT-20H00451, KAKENHI-PROJECT-21K19215
  • [Journal Article] Cell-based flow cytometry assay for simultaneous detection of multiple autoantibodies in a single serum sample2022

    • Author(s)
      Tanimura Yukihiro、Hiroaki Yoko、Mori Masahiro、Fujiyoshi Yoshinori
    • Journal Title

      Analytical Biochemistry

      Volume: 650 Pages: 114721-114721

    • DOI

      10.1016/j.ab.2022.114721

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H00451
  • [Journal Article] Discovery of anti-inflammatory physiological peptides that promote tissue repair by reinforcing epithelial barrier formation2021

    • Author(s)
      Oda Y., Takahashi C., Harada S., Nakamura S., Sun D., Kiso K., Urata Y., Miyachi H., Fujiyoshi Y., Honigmann A., Uchida S., Ishihama, Y. and Toyoshima, F.
    • Journal Title

      Science Advances

      Volume: 7 Issue: 47 Pages: 1-14

    • DOI

      10.1126/sciadv.abj6895

    • NAID

      120007169950

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-21H05283, KAKENHI-PROJECT-20H00451, KAKENHI-PROJECT-21J13083, KAKENHI-PROJECT-16H06280, KAKENHI-PLANNED-21H05286
  • [Journal Article] Crystal structure of a human plasma membrane phospholipid flippase2020

    • Author(s)
      Nakanishi Hanayo、Irie Katsumasa、Segawa Katsumori、Hasegawa Kazuya、Fujiyoshi Yoshinori、Nagata Shigekazu、Abe Kazuhiro
    • Journal Title

      Journal of Biological Chemistry

      Volume: 295 Issue: 30 Pages: 10180-10194

    • DOI

      10.1074/jbc.ra120.014144

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05785, KAKENHI-PROJECT-20H00451, KAKENHI-PROJECT-17H03653, KAKENHI-PROJECT-18H02615, KAKENHI-PROJECT-19K22394
  • [Journal Article] Cryo-EM structures of undocked innexin-6 hemichannels in phospholipids2020

    • Author(s)
      Burendei Batuujin、Shinozaki Ruriko、Watanabe Masakatsu、Terada Tohru、Tani Kazutoshi、Fujiyoshi Yoshinori、Oshima Atsunori
    • Journal Title

      Science Advances

      Volume: 6 Issue: 7

    • DOI

      10.1126/sciadv.aax3157

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-19H03165, KAKENHI-PROJECT-17K19347, KAKENHI-PROJECT-17H03683
  • [Journal Article] Transport Cycle of Plasma Membrane Flippase ATP11C by Cryo-EM2020

    • Author(s)
      Nakanishi Hanayo、Nishizawa Tomohiro、Segawa Katsumori、Nureki Osamu、Fujiyoshi Yoshinori、Nagata Shigekazu、Abe Kazuhiro
    • Journal Title

      Cell Reports

      Volume: 32 Issue: 13 Pages: 108208-108208

    • DOI

      10.1016/j.celrep.2020.108208

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05785, KAKENHI-PROJECT-20H00451, KAKENHI-PROJECT-17H03653, KAKENHI-PROJECT-18H02615, KAKENHI-PROJECT-19K22394, KAKENHI-PROJECT-20H03216
  • [Journal Article] A native prokaryotic voltage-dependent calcium channel with a novel selectivity filter sequence2020

    • Author(s)
      Shimomura Takushi、Yonekawa Yoshiki、Nagura Hitoshi、Tateyama Michihiro、Fujiyoshi Yoshinori、Irie Katsumasa
    • Journal Title

      eLife

      Volume: 9 Pages: 1-21

    • DOI

      10.7554/elife.52828

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-17K08557, KAKENHI-PROJECT-17K17795
  • [Journal Article] Structural insights into thermostabilization of leucine dehydrogenase from its atomic structure by cryo-electron microscopy2019

    • Author(s)
      Yamaguchi Hiroki、Kamegawa Akiko、Nakata Kunio、Kashiwagi Tatsuki、Mizukoshi Toshimi、Fujiyoshi Yoshinori、Tani Kazutoshi
    • Journal Title

      Journal of Structural Biology

      Volume: 205 Issue: 1 Pages: 11-21

    • DOI

      10.1016/j.jsb.2018.12.001

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-17K19347
  • [Journal Article] A single K+-binding site in the crystal structure of the gastric proton pump2019

    • Author(s)
      Yamamoto Kenta、Dubey Vikas、Irie Katsumasa、Nakanishi Hanayo、Khandelia Himanshu、Fujiyoshi Yoshinori、Abe Kazuhiro
    • Journal Title

      eLife

      Volume: 8

    • DOI

      10.7554/elife.47701

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-17H03653, KAKENHI-PROJECT-17K17795
  • [Journal Article] Crystal structures of the gastric proton pump2018

    • Author(s)
      Abe Kazuhiro、Irie Katsumasa、Nakanishi Hanayo、Suzuki Hiroshi、Fujiyoshi Yoshinori
    • Journal Title

      Nature

      Volume: 556 Issue: 7700 Pages: 214-218

    • DOI

      10.1038/s41586-018-0003-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-17K17795, KAKENHI-PROJECT-17H03653
  • [Journal Article] The cryo-EM structure of gastric H+,K+-ATPase with bound BYK99, a high-affinity member of K+-competitive, imidazo[1,2-a]pyridine inhibitors2017

    • Author(s)
      Abe Kazuhiro、Shimokawa Jun、Naito Mao、Munson Keith、Vagin Olga、Sachs George、Suzuki Hiroshi、Tani Kazutoshi、Fujiyoshi Yoshinori
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 6632-6632

    • DOI

      10.1038/s41598-017-06698-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19347, KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-17H03653, KAKENHI-PROJECT-15H05641
  • [Journal Article] X-ray structures of endothelin ETB receptor bound to clinical antagonist bosentan and its analog2017

    • Author(s)
      Shihoya Wataru、Nishizawa Tomohiro、Yamashita Keitaro、Inoue Asuka、Hirata Kunio、Kadji Francois Marie Ngako、Okuta Akiko、Tani Kazutoshi、Aoki Junken、Fujiyoshi Yoshinori、Doi Tomoko、Nureki Osamu
    • Journal Title

      Nature Structural & Molecular Biology

      Volume: 24 Issue: 9 Pages: 758-764

    • DOI

      10.1038/nsmb.3450

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K07172, KAKENHI-PROJECT-17K19347, KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-17J30010, KAKENHI-PROJECT-16H06294, KAKENHI-PROJECT-17H05000
  • [Journal Article] Crystal structures of claudins: insights into their intermolecular interactions.2017

    • Author(s)
      H. Suzuki, K. Tani, Y. Fujiyoshi
    • Journal Title

      Ann. N. Y. Acad. Sci.

      Volume: N/A Issue: 1 Pages: 25-34

    • DOI

      10.1111/nyas.13371

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26440024, KAKENHI-PROJECT-17K19347, KAKENHI-PROJECT-15H05775
  • [Journal Article] Activation mechanism of endothelin ETB receptor by endothelin-1.2016

    • Author(s)
      W. Shihoya, T. Nishizawa, A. Okuta, K. Tani, N. Dohmae, Y. Fujiyoshi, O. Nureki and T. Doi
    • Journal Title

      Nature

      Volume: 537 Issue: 7620 Pages: 363-368

    • DOI

      10.1038/nature19319

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-15J09780, KAKENHI-PROJECT-26440024, KAKENHI-PROJECT-16K07172, KAKENHI-PROJECT-16H06294
  • [Journal Article] Two-dimensional crystal structure of aquaporin-4 bound to the inhibitor acetazolamide.2016

    • Author(s)
      A. Kamegawa, Y. Hiroaki, K. Tani, and Y. Fujiyoshi
    • Journal Title

      Microscopy

      Volume: 65 Issue: 2 Pages: 177-184

    • DOI

      10.1093/jmicro/dfv368

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-26440024
  • [Journal Article] Atomic structure of the innexin-6 gap junction channel determined by cryo-EM.2016

    • Author(s)
      A. Oshima, K. Tani and Y. Fujiyoshi
    • Journal Title

      Nature Communications

      Volume: 7 Issue: 1 Pages: 13681-13681

    • DOI

      10.1038/ncomms13681

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-26440024, KAKENHI-PROJECT-16K07266
  • [Journal Article] Characterization of physiologic phenotypes of dentate gyrus synapses of PDZ1/2 domain-deficient PSD-95 knockin mice.2016

    • Author(s)
      H. Nagura, T. Doi and Y. Fujiyoshi
    • Journal Title

      European Journal of Neuroscience

      Volume: 43 Issue: 5 Pages: 618-625

    • DOI

      10.1111/ejn.13155

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Journal Article] Thermostabilization of the human endothelin type-B receptor2016

    • Author(s)
      Akiko Okuta, Kazutoshi Tani, Shoko Nishimura, Yoshinori Fujiyoshi, and Tomoko Doi*
    • Journal Title

      Journal of Molecular Biology

      Volume: in press Issue: 11 Pages: 1-10

    • DOI

      10.1016/j.jmb.2016.03.024

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26640102, KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-26440024, KAKENHI-PROJECT-16K07172
  • [Journal Article] Molecular determinants of prokaryotic voltage-gated sodium channels for recognition of local anesthetics.2016

    • Author(s)
      T. Shimomura, K. Irie and Y. Fujiyoshi
    • Journal Title

      FEBS Journal

      Volume: 283 Issue: 15 Pages: 2881-2895

    • DOI

      10.1111/febs.13776

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Journal Article] GraDeR: membrane protein complex preparation for single particle cryo-EM.2015

    • Author(s)
      Hauer F., Gerle C., Fischer N., Oshima A., Shinzawa-Itoh K., Shimada S., Yokoyama K., Fujiyoshi Y. & Stark H.
    • Journal Title

      Structure

      Volume: 23 Issue: 9 Pages: 1769-1775

    • DOI

      10.1016/j.str.2015.06.029

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K14464, KAKENHI-PROJECT-15H05775, KAKENHI-PROJECT-26650039, KAKENHI-PROJECT-26840019
  • [Journal Article] An intracellular domain with a novel sequence regulates cell surface expression and synaptic clustering of leucine-rich repeat transmembrane proteins in hippocampal neurons.2015

    • Author(s)
      K. Minatohara, Y. Murata, Y. Fujiyoshi and T. Doi
    • Journal Title

      Journal of Neurochemistry

      Volume: 134 Issue: 4 Pages: 618-628

    • DOI

      10.1111/jnc.13159

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Journal Article] Bovine F1FoATP synthase monomers bend the lipid bilayer in 2D membrane crystals.2015

    • Author(s)
      C. Jiko, K.M. Davies, K.S. Itoh, K. Tani, S. Maeda, D.J. Mills, T. Tsukihara, Y. Fujiyoshi W. Kuehlbrandt and C. Gerle
    • Journal Title

      eLIFE

      Volume: 06119 Pages: 1-36

    • DOI

      10.7554/elife.06119

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-22227004, KAKENHI-PROJECT-26440024, KAKENHI-PROJECT-15K14464, KAKENHI-PROJECT-13J05370
  • [Journal Article] Systematic comparison of molecular conformations of H+,K+-ATPase reveals an important contribution of the A-M2 linker for the luminal gating.2014

    • Author(s)
      K. Abe, K. Tani and Y. Fujiyoshi
    • Journal Title

      Journal of Biological Chemistry

      Volume: 289 Issue: 44 Pages: 30590-30601

    • DOI

      10.1074/jbc.m114.584623

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-22227004, KAKENHI-PROJECT-26440024, KAKENHI-PROJECT-26711005
  • [Journal Article] Control of spontaneous Ca2+ transients is critical for neuronal maturation in the developing neocortex.2014

    • Author(s)
      Y. Bando, K. Irie, T. Shimomura, H. Umeshima, Y. Kushida, M. Kengaku, Y. Fujiyoshi, T. Hirano and Y. Tagawa
    • Journal Title

      Cerebral Cortex

      Volume: 1 Issue: 1 Pages: 1-12

    • DOI

      10.1093/cercor/bhu180

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22227004, KAKENHI-PUBLICLY-25110717, KAKENHI-PUBLICLY-25115716, KAKENHI-PROJECT-26290005
  • [Journal Article] Crystal structure of a claudin provides insight into the architecture of tight junctions2014

    • Author(s)
      H. Suzuki, T. Nishizawa, K. Tani, Y. Yamazaki, A. Tamura, R. Ishitani, N. Dohmae, S. Tsukita, O. Nureki and Y. Fujiyoshi
    • Journal Title

      Science

      Volume: 344 Pages: 304-307

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770147
  • [Journal Article] Water channel structures analysed by electron crystallography2014

    • Author(s)
      K. Tani and Y. Fujiyoshi
    • Journal Title

      Biochim. Biophys. Acta

      Volume: 1840 Pages: 1605-1613

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770147
  • [Journal Article] Carbon sandwich preparation preserves quality of two-dimensional crystals for cryo-electron microscopy2013

    • Author(s)
      F. Yang, K. Abe, K. Tani and Y. Fujiyoshi
    • Journal Title

      Microscopy

      Volume: 62 Pages: 597-606

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770147
  • [Journal Article] Oligomeric structure and functional characterization of C. elegans innexin-6 gap junction channels.2013

    • Author(s)
      A. Oshima, T Matsuzawa, K. Nishikawa and Y. Fujiyoshi
    • Journal Title

      J. Biol. Chem.

      Volume: 288 Issue: 15 Pages: 10513-10521

    • DOI

      10.1074/jbc.m112.428383

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Journal Article] The four-transmembrane protein IP39 of Euglena forms strand by a trimeric unit repeat.2013

    • Author(s)
      H. Suzuki, Y Ito, Y Yamazaki, K Mineta, M Uji, K. Abe, K. Tani, Y. Fujiyoshi and S. Tsukita.
    • Journal Title

      Nature Commun.

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Journal Article] Novel dichromatic chromatophores in the integument of mandarin fish Synchiropus splendidus.2013

    • Author(s)
      M. Goda, Y. Fujiyoshi, M. Sugimoto and R. Fujii.
    • Journal Title

      Biol. Bull.

      Volume: 224 Pages: 14-17

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Journal Article] Oligomeric structure and functional characterization of C. elegans innexin-6 gap junction channels.2013

    • Author(s)
      A. Oshima, T Matsuzawa, K. Nishikawa and Y. Fujiyoshi.
    • Journal Title

      J. Biol. Chem.

      Volume: in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Journal Article] Two alternative conformations of a voltage-gated sodium channel2013

    • Author(s)
      C. J. Tsai, K. Tani, K. Irie, Y. Hiroaki, T. Shimomura, D. G. McMillan, G. M. Cook, G. F.X. Schertler, Y. Fujiyoshi and X. D. Li
    • Journal Title

      J. Mol. Biol

      Volume: 425 Pages: 4074-4088

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770147
  • [Journal Article] Carbon sandwich preparation preserves quality of two-dimensional crystals for cryo-electron microscopy.2013

    • Author(s)
      F. Yang, K. Abe, K. Tani and Y. Fujiyoshi
    • Journal Title

      Microscopy

      Volume: 62 Issue: 6 Pages: 597-606

    • DOI

      10.1093/jmicro/dft038

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22227004, KAKENHI-PROJECT-24870014
  • [Journal Article] Strand formation by a trimeric unit repeat of four-transmembrane proteins in Euglena2013

    • Author(s)
      H. Suzuki, Y. Ito, Y. Yamazaki, K. Mineta, M. Uji, K. Abe, K. Tani, Y. Fujiyoshi and S. Tsukita
    • Journal Title

      Nat. Commun

      Volume: 4 Pages: 1-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770147
  • [Journal Article] Visualization of two distinct states of disassembly in the bacterial V-ATPase from Thermus thermophilus.2013

    • Author(s)
      K. Tani, C. P. Arthur, M. Tamakoshi, K. Yokoyama, K. Mitsuoka, Y. Fujiyoshi and C. Gerle
    • Journal Title

      Microscopy

      Volume: 62 Issue: 4 Pages: 467-474

    • DOI

      10.1093/jmicro/dft020

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22227004, KAKENHI-PROJECT-22770147, KAKENHI-PROJECT-24370059
  • [Journal Article] Visualization of two distinct states of disassembly in the bacterial V-ATPase from Thermus Thermophilus2013

    • Author(s)
      K. Tani, C.P. Arthur, M. Tamakoshi, K. Yokoyama, K. Mitsuoka, Y. Fujiyoshi and C. Gerle
    • Journal Title

      Microscopy

      Volume: 62 Pages: 467-474

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770147
  • [Journal Article] Two alternative conformations of a voltage-gated sodium channel.2013

    • Author(s)
      CJ. Tsai, K. Tani, K. Irie, Y. Hiroaki, T. Shimomura, DG. McMillan, GM. Cook, GFX. Schertler, Y. Fujiyoshi and XD. Li
    • Journal Title

      J. Mol. Biol.

      Volume: 425 Issue: 22 Pages: 4074-4088

    • DOI

      10.1016/j.jmb.2013.06.036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22227004, KAKENHI-PROJECT-22770147, KAKENHI-PROJECT-23570191
  • [Journal Article] The C-terminal helical bundle of the tetrameric prokayotic sodium channel accelerates the inactivation rate2012

    • Author(s)
      K.Irie, T.Shimomura, Y.Fujiyoshi
    • Journal Title

      Nature Commun.

      Volume: (in press) Issue: 1 Pages: 1-8

    • DOI

      10.1038/ncomms1797

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Journal Article] Cryo-EM structure of gastric H+, K+-ATPase with a single occupied cation-binding site2012

    • Author(s)
      K. Abe, K. Tani, T. Friedrich and Y. Fujiyoshi
    • Journal Title

      Proc. Natl. Acad. Sci. U.S.A.

      Volume: 109 Pages: 18401-18406

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770147
  • [Journal Article] Cryo-EM structure of gastric H+,K+-ATPase with a single occupied cation-binding site.2012

    • Author(s)
      K. Abe, K. Tani, T. Friedrich and Y. Fujiyoshi
    • Journal Title

      Proc. Natl. Acad. Sci. U S A.

      Volume: 109 Issue: 45 Pages: 18401-18406

    • DOI

      10.1073/pnas.1212294109

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22227004, KAKENHI-PROJECT-22770147
  • [Journal Article] Gating movement of acetylcholine receptor caught by plunge-freezing.2012

    • Author(s)
      N. Unwin and Y. Fujiyoshi
    • Journal Title

      J. Mol. Biol.

      Volume: 422 Issue: 5 Pages: 617-634

    • DOI

      10.1016/j.jmb.2012.07.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Journal Article] Arrangement and mobility of the voltage sensor domain in prokaryotic voltage-gated sodium channels2011

    • Author(s)
      T.Shimomura, K.Irie, H.Nagura, T.Imai, Y.Fujiyoshi
    • Journal Title

      J.Biol.Chem.

      Volume: 286 Pages: 7409-7417

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Journal Article] Water permeability and characterization of aquaporin-112011

    • Author(s)
      K.Yakata, K.Tani, Y.Fujiyoshi
    • Journal Title

      J.Struct.Biol.

      Volume: 174 Pages: 315-320

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Journal Article] Conformational rearrangement of gastric H^+,K^+-ATPase induced by an acid suppressant2011

    • Author(s)
      K.Abe, K.Tani, Y.Fujiyoshi
    • Journal Title

      Nature Commun.

      Volume: 2 Issue: 1

    • DOI

      10.1038/ncomms1154

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Journal Article] Water permeability and characterization of aquaporin-112011

    • Author(s)
      K. Yakata, K. Tani$ and Y. Fujiyoshi ($Corresponding author. )
    • Journal Title

      J. Struct. Biol

      Volume: 174 Pages: 315-320

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770147
  • [Journal Article] Electron tomographic analysis of gap junctions in the lateral giant fibers of crayfish2011

    • Author(s)
      Y.Ohta, K.Nishikawa, Y.Hiroaki, Y.Fujiyoshi
    • Journal Title

      J.Struct.Biol.

      Volume: 175 Pages: 49-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Journal Article] Asymmetric Configurations and N-terminal Rearrangements in Connexin26 Gap Junction Channels2011

    • Author(s)
      A. Oshima, K. Tani, M. M. Toloue, Y. Hiroaki, A. Smock, S. Inukai, A. Cone, B. J. Nicholson, G. E. Sosinsky and Y. Fujiyoshi
    • Journal Title

      J. Mol. Biol

      Volume: 405 Pages: 724-735

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770147
  • [Journal Article] Conformational rearrangement of gastric H^+, K^+-ATPase induced by an acid suppressant2011

    • Author(s)
      K. Abe, K. Tani and Y. Fujiyoshi
    • Journal Title

      Nat. Commun

      Volume: 2 Pages: 155-155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770147
  • [Journal Article] Asymmetric configurations and N-terminal rearrangements in connexin26 gap junction channels2011

    • Author(s)
      A.Oshima, K.Tani, M.M.Toloue, Y.Hiroaki, A.Smock, S.Inukai, A.Cone, B.J.Nicholson, G.E.Snsinski, Y.Fujiyoshi
    • Journal Title

      J.Mol.Biol.

      Volume: 405 Pages: 724-735

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Journal Article] Water permeability and characterization of aquaporin-112011

    • Author(s)
      K.Yakata, K.Tani, Y.Fujiyoshi
    • Journal Title

      JOURNAL OF STRUCTURAL BIOLOGY

      Volume: 174 Issue: 2 Pages: 315-320

    • DOI

      10.1016/j.jsb.2011.01.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770147
  • [Journal Article] Structural and functional characterization of H^+, K^+-ATPase with bound fluorinated phosphate analogs2010

    • Author(s)
      K. Abe, K. Tani and Y. Fujiyoshi
    • Journal Title

      J. Struct. Biol

      Volume: 170 Pages: 60-68

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770147
  • [Journal Article] Influence of the cytoplasmic domains of aquaporin-4 on water conduction and array formation2010

    • Author(s)
      T. Mitsuma, K. Tani, Y. Hiroaki, A. Kamegawa, H. Suzuki, H. Hibino, Y. Kurachi and Y. Fujiyoshi
    • Journal Title

      J. Mol. Biol

      Volume: 402 Pages: 669-681

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22770147
  • [Journal Article] Structure of the connexin-26 gap junction channel at 3.5 Å resolution.2009

    • Author(s)
      S. Maeda, S. Nakagawa, M. Suga, E. Yamashita, A. Oshima, Y. Fujiyoshi and T. Tsukihara
    • Journal Title

      Nature 458

      Pages: 597-602

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Journal Article] Inter-subunit interaction of gastric H^+, K^+-ATPase prevents reverse reaction of the transport cycle.2009

    • Author(s)
      K. Abe, K. Tani, T. Nishizawa and Y. Fujiyoshi
    • Journal Title

      EMBO J. (in the press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Journal Article] Acetazolamide reversibly inhibits water conduction by aquaporin-4.2009

    • Author(s)
      Y. Tanimura, Y. Hiroaki and Y. Fujiyoshi
    • Journal Title

      J. Struct. Biol. 166

      Pages: 16-21

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Journal Article] Mechanism of Aquaporin-4's Fast and Highly Selective Water Conduction and Proton Exclusion.2009

    • Author(s)
      K. Tani, T. Mitsuma, Y. Hiroaki, A. Kamegawa, K. Nishikawa, Y. Tanimura and Y. Fujiyoshi
    • Journal Title

      J. Mol. Biol. 389

      Pages: 694-706

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Journal Article] 膜タンパク質の構造から見たチャネルの分子機構2008

    • Author(s)
      藤吉好則
    • Journal Title

      固体物理 43

      Pages: 35-44

    • Data Source
      KAKENHI-PROJECT-16001005
  • [Journal Article] Formation of aquaporin-4 arrays is inhibited by palmitoylation of N-terminal cysteine residues.2008

    • Author(s)
      H. Suzuki, K. Nishikawa, Y. Hiroaki and Y. Fujiyoshi
    • Journal Title

      Biochem. Biophys. Acta. 1778

      Pages: 1181-1189

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Journal Article] Three-dimensional structure of a human connexin26 gap junction channel reveals a plug in the vestibule.2007

    • Author(s)
      A. Oshima, K. Tani, Y. Hiroaki, Y. Fujiyoshi and G. E. Sosinsky
    • Journal Title

      PNAS 104

      Pages: 10034-10039

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Journal Article] Aquaporin-11 containing a divergent NPA motif has normal water channel activity.2007

    • Author(s)
      K. Yakata, Y. Hiroaki, K. Ishibashi, E. Sohara, S. Sasaki, K. Mitsuoka and Y. Fujiyoshi
    • Journal Title

      Biochim. Biophys. Acta. 1768

      Pages: 688-693

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Journal Article] Implications of the Aquaporin-4 Structure on Array Formation and Cell Adhesion.2006

    • Author(s)
      Y. Hiroaki, K. Tani, A. Kamegawa, N. Gyobu, K. Nishikawa, H. Suzuki, T. Walz, S. Sasaki, K. Mitsuoka, K. Kimura, A. Mizoguchi and Y. Fujiyoshi
    • Journal Title

      J. Mol. Biol. 355

      Pages: 628-639

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Journal Article] Neurosteroid pregnenolone sulfate enhances glutamatergic synaptic transmission by facilitating presynaptic calcium currents at the calyx of Held of immature rats.2006

    • Author(s)
      T. Hige, Y. Fujiyoshi and T. Takahashi
    • Journal Title

      Eur. J. Neurosci. 24

      Pages: 1955-1966

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Journal Article] Lipid-protein interactions in double-layered two-dimensional AQP0 crystals.2005

    • Author(s)
      T. Gonen, Y. Cheng, P. Sliz, Y. Hiroaki, Y. Fujiyoshi, S. C. Harrison and T. Walz
    • Journal Title

      Nature 438

      Pages: 633-638

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Journal Article] 水チャネルの構造と機能2005

    • Author(s)
      藤吉 好則
    • Journal Title

      蛋白質 核酸 酵素 50・10

      Pages: 1278-1283

    • Data Source
      KAKENHI-PROJECT-16001005
  • [Patent] 試料作製方法および支持膜2020

    • Inventor(s)
      藤吉好則、石川勇
    • Industrial Property Rights Holder
      株式会社CeSPIA、日本電子株式会社
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2020-114833
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-20H00451
  • [Patent] 3次元像構築方法、画像処理装置、および電子顕微鏡(再公表特許)2015

    • Inventor(s)
      藤吉 好則、石川 勇、細木 直樹
    • Industrial Property Rights Holder
      国立大学法人名古屋大学、日本電子株式会社
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015
    • Acquisition Date
      2017
    • Overseas
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Patent] 3次元像構築方法、画像処理装置、および電子顕微鏡2014

    • Inventor(s)
      藤吉 好則
    • Industrial Property Rights Holder
      藤吉 好則
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-169003
    • Filing Date
      2014-08-22
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Patent] Specimen stage-moving device for charged-particle beam system2008

    • Inventor(s)
      Yoshinori Fujiyoshi, Tomohisa Fukuda
    • Industrial Property Rights Holder
      JEOL Ltd.
    • Filing Date
      2008-03-28
    • Overseas
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Patent] Specimen stage-moving device for charged-particle beam system2008

    • Inventor(s)
      Yoshinori Fujiyoshi, Tomohisa Fukuda
    • Industrial Property Rights Holder
      JEOL Ltd.
    • Filing Date
      2008-03-31
    • Overseas
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Patent] 荷電粒子線装置の試料ステージ移動装置2007

    • Inventor(s)
      藤吉好則, 福田知久
    • Industrial Property Rights Holder
      京都大学, 日本電子(株)
    • Industrial Property Number
      2007-094862
    • Filing Date
      2007-03-30
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Patent] 荷電粒子線装置の試料ステージ移動装置2007

    • Inventor(s)
      藤吉 好則, 福田 知久
    • Industrial Property Rights Holder
      京都大学日本電子(株)
    • Industrial Property Number
      2007-094862
    • Filing Date
      2007-03-30
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Patent] トップエントリ式試料ステージ傾斜装置2005

    • Inventor(s)
      藤吉 好則, 出口 俊二
    • Industrial Property Rights Holder
      京都大学, 日本電子(株)
    • Industrial Property Number
      2005-205558
    • Filing Date
      2005-07-14
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Patent] トップエントリ式試料ステージ傾斜装置2005

    • Inventor(s)
      藤吉好則, 出口俊二
    • Industrial Property Rights Holder
      京都大学, 日本電子(株)
    • Industrial Property Number
      2005-205558
    • Filing Date
      2005-07-14
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] クライオ電顕法の紹介2023

    • Author(s)
      藤吉 好則
    • Organizer
      第46回日本神経科学大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H00451
  • [Presentation] Structural physiology and Structure-Guided Drug Development2022

    • Author(s)
      藤吉好則
    • Organizer
      20th Surugadai International Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H00451
  • [Presentation] クライオ電子顕微鏡法の発展と展望2022

    • Author(s)
      藤吉 好則
    • Organizer
      第127回日本解剖学会総会・全国学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H00451
  • [Presentation] クライオ電子顕微鏡を活用した構造創薬2021

    • Author(s)
      藤吉 好則
    • Organizer
      CBI研究機構量子構造生命科学研究所、中性子構造生物学研究会、生物生体材料研究会、合同シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H00451
  • [Presentation] クライオ電子顕微鏡の現状と展望2021

    • Author(s)
      藤吉好則
    • Organizer
      よこはまNMR研究会 第66回ワークショップ「クライオ電子顕微鏡」
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H00451
  • [Presentation] クライオ電顕が神経化学分野に役立つ時代に2021

    • Author(s)
      藤吉 好則
    • Organizer
      第64回日本神経化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H00451
  • [Presentation] クライオ電子顕微鏡が激変させたタンパク質の立体構造解析技術2020

    • Author(s)
      藤吉好則
    • Organizer
      第48回日本臨床免疫学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H00451
  • [Presentation] クライオ電顕が医学・薬学分野に役立つ時代に2020

    • Author(s)
      藤吉好則
    • Organizer
      nano tech 2020 特別シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] 生体分子を観ると創薬に役立つ2019

    • Author(s)
      藤吉好則
    • Organizer
      日本顕微鏡学会市民公開講座
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] クライオ電子顕微鏡を用いた構造創薬の現状2019

    • Author(s)
      藤吉好則
    • Organizer
      第13回 In vivo実験医学シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] クライオ電子顕微鏡による構造解析と構造創薬2019

    • Author(s)
      藤吉好則
    • Organizer
      クリニカルサミット研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] Structure-guided drug development by cryo-EM [Plenary Lecture]2019

    • Author(s)
      藤吉好則
    • Organizer
      International Symposium on Diffraction Structural Biology 2019
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] 構造生物学を激変させたクライオ電顕2019

    • Author(s)
      藤吉好則
    • Organizer
      第二回 形態解析ワークショップ ― 多様な顕微鏡を用いて
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] Drug rescuing based on structure analyses by cryo-EM2019

    • Author(s)
      藤吉好則
    • Organizer
      インベスターR&D Day
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] Cryo-EM changes structural biology [Tutorial Lecture]2019

    • Author(s)
      藤吉好則
    • Organizer
      ALC '19
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] Structural physiology of channels [Special Lecture]2019

    • Author(s)
      藤吉好則
    • Organizer
      倉智嘉久教授退職記念国際シンポジウム
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] セッション4 クライオ電顕の現状と展望[ディスカッションリーダー]2018

    • Author(s)
      藤吉好則
    • Organizer
      原子・分子・光科学(AMO)討論会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] Structural physiology of membrane proteins2018

    • Author(s)
      藤吉好則
    • Organizer
      Special Seminar at MRC-LMB
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] 構造生物学を激変させたクライオ電顕2018

    • Author(s)
      藤吉好則
    • Organizer
      岡山大学 特別講演会・学院講義
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] Microscopyシンポジウム「顕微鏡分野における世界の学術出版動向」2018

    • Author(s)
      藤吉好則
    • Organizer
      日本顕微鏡学会 第74回学術講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] 構造生理学と創薬2018

    • Author(s)
      藤吉好則
    • Organizer
      第58回生物物理若手の会 夏の学校
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] Drug Rescuing by Cryo-EM2018

    • Author(s)
      藤吉好則
    • Organizer
      第18回国際薬理学・臨床薬理学会議
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] Drug Rescuing Based on Structure Analyses by Cryo-EM2018

    • Author(s)
      藤吉好則
    • Organizer
      CryoEM Symposium "The Cryo-EM Revolution and Future Breakthroughs"
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] High resolution structure analyses by cryo-EM2018

    • Author(s)
      藤吉好則
    • Organizer
      Scottish Centre for Macromolecular Imaging Opening Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] Structure-guided drug development by Cryo-EM [Keynote]2018

    • Author(s)
      藤吉好則
    • Organizer
      The official Opening of the electron Bio-Imaging Centre (eBIC) at Diamond Light Source
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] クライオ電顕法を用いた構造解析と医薬応用2018

    • Author(s)
      藤吉好則
    • Organizer
      東京医科歯科大学 難治疾患研究所 講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] Drug Rescuing based on structure analyses by Cryo-EM2018

    • Author(s)
      藤吉好則
    • Organizer
      2018 International Meeting on 22nd MDO/33rd JSSX
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] 構造生物学を激変させたクライオ電顕2018

    • Author(s)
      藤吉好則
    • Organizer
      第34回 分析電子顕微鏡討論会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] クライオ電顕法の発展と創薬応用への可能性2018

    • Author(s)
      藤吉好則
    • Organizer
      平成30年度 後期(秋季)有機合成化学講習会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] 構造生物学を激変させたCryoEM2017

    • Author(s)
      藤吉好則
    • Organizer
      微細構造解析プラットフォームシンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] Structures of Physiology of membrane proteins2017

    • Author(s)
      藤吉好則
    • Organizer
      International Cryo-EM symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] 構造生物学を激変させたクライオ電子顕微鏡法2017

    • Author(s)
      藤吉好則
    • Organizer
      CSJ化学フェスタ2017
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] 膜タンパク質の構造生理学2017

    • Author(s)
      藤吉好則
    • Organizer
      日本膜学会第39年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] Structural studies of membrane proteins by cryo-EM2017

    • Author(s)
      藤吉好則
    • Organizer
      第17回日本タンパク質科学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] 創薬に役立つCryoEM2017

    • Author(s)
      藤吉好則
    • Organizer
      第30回バイオメディカル分析化学シンポジウム
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] Structure-Guided Drug Development by CryoEM2017

    • Author(s)
      藤吉好則
    • Organizer
      International Symposium on Cryo-EM - past and future challenges
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] Structures of membrane proteins analyzed by cryo-EM2017

    • Author(s)
      藤吉好則
    • Organizer
      新学術領域研究「脂質クオリティが解き明かす生命現象」公開国際シンポジウム
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] 構造生物学の激変2017

    • Author(s)
      藤吉 好則
    • Organizer
      生理学研究所 平成28年度末シンポジウム
    • Place of Presentation
      生理学研究所
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] For effective structure analyses of membrane proteins2017

    • Author(s)
      藤吉好則
    • Organizer
      Symposium to celebrate Gunnar
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] 薬理学につながる構造生理学研究2016

    • Author(s)
      藤吉好則
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-03-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] 構造に指南された創薬基盤技術開発2016

    • Author(s)
      藤吉好則
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-03-26
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] Development of the structural biology field2016

    • Author(s)
      Yoshinori Fujiyoshi
    • Organizer
      THE 13TH NIKKO INTERNATIONAL SYMPOSIUM 2016
    • Place of Presentation
      自治医科大学
    • Year and Date
      2016-10-09
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] Issues to Be Considered for Image Based Structure Analysis2016

    • Author(s)
      Yoshinori Fujiyoshi
    • Organizer
      Gordon Research Conferences -Three Dimensional Electron Microscopy-
    • Place of Presentation
      The Chinese University of Hong Kong Hong Kong, China
    • Year and Date
      2016-06-19
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] Dramatic Changes on Cryo-Electron Microscopy2016

    • Author(s)
      Yoshinori Fujiyoshi
    • Organizer
      The XXVIIth International Conference on Magnetic Resonance in Biological Systems (ICMRBS2016)
    • Place of Presentation
      国立京都国際会館
    • Year and Date
      2016-08-21
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] Structural physiology of channels2016

    • Author(s)
      Yoshinori Fujiyoshi
    • Organizer
      内藤コンファレンス -In the Vanguard of Structural Biology: Revolutionizing Life Sciences-
    • Place of Presentation
      シャトレーゼ ガトーキングダム 札幌
    • Year and Date
      2016-10-04
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] 構造に指南された創薬戦略の現状と展望2016

    • Author(s)
      藤吉 好則
    • Organizer
      第34回メディシナルケミストリーシンポジウム
    • Place of Presentation
      つくば国際会議場
    • Year and Date
      2016-11-30
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] Model for the architecture of claudin-based paracellular ion channels.2015

    • Author(s)
      谷一寿、鈴木博視、田村淳、月田早智子、藤吉好則
    • Organizer
      第71回 日本顕微鏡学会年会
    • Place of Presentation
      京都
    • Year and Date
      2015-05-14
    • Data Source
      KAKENHI-PROJECT-26440024
  • [Presentation] タンパク質と脂質分子の協調2015

    • Author(s)
      藤吉好則
    • Organizer
      第53回日本生物物理学会年会
    • Place of Presentation
      金沢大学
    • Year and Date
      2015-09-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] アクアポリン-4の水銀による水透過阻害機構の構造学的解明2015

    • Author(s)
      亀川亜希子、小林一美、関口俊之、廣明洋子、藤吉好則、谷 一寿
    • Organizer
      第71回 日本顕微鏡学会年会
    • Place of Presentation
      京都
    • Year and Date
      2015-05-14
    • Data Source
      KAKENHI-PROJECT-26440024
  • [Presentation] Application of direct electron detector to electron crystallgoraphy.2015

    • Author(s)
      谷一寿、小林一美、亀川亜希子、藤吉好則
    • Organizer
      第71回 日本顕微鏡学会年会
    • Place of Presentation
      京都
    • Year and Date
      2015-05-14
    • Data Source
      KAKENHI-PROJECT-26440024
  • [Presentation] Structure-Guided Drug Development Based on Cryo-Electron Microscopy2015

    • Author(s)
      藤吉好則
    • Organizer
      The 2nd East-Asia Microscopy Conference
    • Place of Presentation
      姫路商工会議所
    • Year and Date
      2015-11-24
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] Structural physiology of cell adhesive channels2015

    • Author(s)
      藤吉好則
    • Organizer
      第31回国際生物学賞記念シンポジウム
    • Place of Presentation
      京都国際会議場
    • Year and Date
      2015-12-05
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] 素朴な疑問と続ける努力2015

    • Author(s)
      藤吉好則
    • Organizer
      Biochemistry and Molecular Biology 2015
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2015-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H05775
  • [Presentation] ヒトの分子レベルからの理解と創薬を目指す結晶学2014

    • Author(s)
      藤吉 好則
    • Organizer
      世界結晶年(IYCr2014)オープニングシンポジウム
    • Place of Presentation
      日本学術会議講堂
    • Invited
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] ヒトを分子構造から知るための電子顕微鏡2013

    • Author(s)
      藤吉 好則
    • Organizer
      「高性能電子顕微鏡により反応科学・ナノ材料科学研究支援拠点」研究報告会
    • Place of Presentation
      名古屋大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] Key technology for structure-guided drug development2013

    • Author(s)
      藤吉 好則
    • Organizer
      Nagoya Symposium
    • Place of Presentation
      名古屋大学
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] 創薬とヒトの分子レベルからの理解を目指して2013

    • Author(s)
      藤吉 好則
    • Organizer
      日本学術会議中部地区会議学術講演会
    • Place of Presentation
      名古屋大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] Structural physiology of channels2013

    • Author(s)
      藤吉 好則
    • Organizer
      International Symposium on Diffraction Structural Biology, Plenary lecture 2013
    • Place of Presentation
      名古屋市中小企業振興会館(吹上ホール)
    • Invited
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] 電子線結晶学による構造生理学研究2013

    • Author(s)
      藤吉 好則
    • Organizer
      日本顕微鏡学会第57回シンポジウム
    • Place of Presentation
      ウインク愛知
    • Invited
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] ELECTRON CRYSTALLOGRAPHY OF EUGLENOID FOUR-TRANSMEMBRANE PROTEIN REVEALED THE LINEAR POLYMERIZATION BY A COMBINATION OF THREE-WAYS OF INTERMOLECULAR INTERACTION2013

    • Author(s)
      鈴木博視, 伊藤泰行, 谷一寿, 山崎裕自, 氏昌未, 峯田克彦, 月田早智子, 藤吉好則
    • Organizer
      Biophysical Society 57th Annual Meeting
    • Place of Presentation
      Philadelphia, PA, USA
    • Data Source
      KAKENHI-PROJECT-22770147
  • [Presentation] Strand-forming polymerization of four-transmembrane proteins in Euglena through intermolecular interactions of tandem trimers2013

    • Author(s)
      伊藤泰行, 鈴木博視, 山崎裕自, 峯田克彦, 氏昌未, 阿部一啓, 谷一寿, 藤吉好則, 月田早智子
    • Organizer
      第62回日本細胞生物学会大会
    • Place of Presentation
      ウィンクあいち
    • Data Source
      KAKENHI-PROJECT-22770147
  • [Presentation] Two alternative conformations of a voltage-gated sodium channel2013

    • Author(s)
      谷一寿, Ching-Ju Tsai, 入江克雅, 廣明洋子, 下村拓史, Duncan G. McMillan, Gregory M. Cook, Gebhard X. Schertler, 藤吉好則, Xiao-Dan Li
    • Organizer
      第51回日本生物物理学会年会
    • Place of Presentation
      京都国際会館
    • Data Source
      KAKENHI-PROJECT-22770147
  • [Presentation] 水チャネルの構造と機能2012

    • Author(s)
      藤吉 好則
    • Organizer
      理事長ファンド指定型 「水科学」 ワークショップ 『水の多様性を極める』 -水科学の現在と未来-
    • Place of Presentation
      和光・鈴木梅太郎ホール
    • Invited
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] Structural Physiology of channels2012

    • Author(s)
      藤吉 好則
    • Organizer
      プレナリーレクチャー・動物細胞工学会
    • Place of Presentation
      名古屋大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] 創薬加速に向けたタンパク質構造解析基盤技術開発「創薬加速基盤技術開発における電子顕微鏡による成果」2012

    • Author(s)
      藤吉好則
    • Organizer
      JBIC2011プロジェクト研究成果報告会
    • Place of Presentation
      東京,日本科学未来館みらいCANホール(招待講演)
    • Year and Date
      2012-02-10
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] 分子構造からヒトを理解するために2012

    • Author(s)
      藤吉 好則
    • Organizer
      第11回先端医療センターMonthly Lecture /公益財団法人先端医療振興財団
    • Place of Presentation
      神戸
    • Invited
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] 分子構造からヒトを理解するために2012

    • Author(s)
      藤吉 好則
    • Organizer
      生物物理若手の会
    • Place of Presentation
      名古屋大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] 水とイオンチャネルの構造生理学2012

    • Author(s)
      藤吉 好則
    • Organizer
      第60回レオロジー討論会
    • Place of Presentation
      名古屋大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] 膜タンパク質の形と働きを観る2012

    • Author(s)
      藤吉 好則
    • Organizer
      日本生物物理学会
    • Place of Presentation
      名古屋大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] ヒトの分子構造を観る2012

    • Author(s)
      藤吉好則
    • Organizer
      東京大学&京都大学グローバルCOEジョイント一般公開シンポジウム『生き物の個性を紐とく:かたち、かかわり、こころ』
    • Place of Presentation
      東京,東京大学小柴ホール(招待講演)
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] イオンと水チャネルの構造と機能2012

    • Author(s)
      藤吉 好則
    • Organizer
      大学院講義医学共通講義VII神経科学入門
    • Place of Presentation
      東京大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] 極低温電子顕微鏡による膜蛋白質や細胞接着膜蛋白質の構造2011

    • Author(s)
      藤吉好則
    • Organizer
      第11回日本蛋白科学会年会
    • Place of Presentation
      大阪,ホテル阪急エキスポパーク(招待講演)
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] 多機能性チャネルの構造と機能2011

    • Author(s)
      藤吉好則
    • Organizer
      自然科学研究機構岡崎統合バイオサイエンスセンター「10周年記念シンポジウム」
    • Place of Presentation
      岡崎,岡崎コンファレンスセンター(招待講演)
    • Year and Date
      2011-02-10
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] Seeing is joy of discovering something new2011

    • Author(s)
      Y.Fujiyoshi
    • Organizer
      JSPS Sweden-Japan Joint Colloquium "Direct Imaging in Bio/Medical Science"
    • Place of Presentation
      Lund (Sweden)(招待講演)
    • Year and Date
      2011-01-18
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] 多機能性チャネルの構造生理学2011

    • Author(s)
      藤吉好則
    • Organizer
      京都大学再生医科学研究所田畑研究所セミナー
    • Place of Presentation
      京都,京都大学再生医科学研究所(招待講演)
    • Year and Date
      2011-05-07
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] 遠くを見ると研究は楽しい2011

    • Author(s)
      藤吉好則
    • Organizer
      第64回社会と科学
    • Place of Presentation
      名古屋,名古屋大学野依記念物質科学研究館(招待講演)
    • Year and Date
      2011-05-31
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] 構造に導かれた創薬を目指す構造生理学の現状2011

    • Author(s)
      藤吉好則
    • Organizer
      創薬を目指した融合領域サマーセミナー2011~最先端メディシナルサイエンスの未来~
    • Place of Presentation
      名古屋,名古屋大学(招待講演)
    • Year and Date
      2011-09-03
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] 膜タンパク質の生理機能を観る2011

    • Author(s)
      藤吉好則
    • Organizer
      理研ASI細胞システム研究コロキウム「細胞を観る・読む・計る」
    • Place of Presentation
      和光,理化学研究所和光研究所梅太郎ホール(招待講演)
    • Year and Date
      2011-12-02
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] 電子線結晶学による膜タンパク質の構造解析に基づく機能研究(蛋白質の高分解能構造と細胞機能発現のメカニズム:オーガナイザーwith前田雄一郎教授)2011

    • Author(s)
      藤吉好則
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都,国立京都国際会館(招待講演)
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] 構造に指南された創薬を目指す構造生理学の現状と展望-遠くを見ると研究は楽しい-2011

    • Author(s)
      藤吉好則
    • Organizer
      京都薬科大学第1回KPUシンポジウム
    • Place of Presentation
      京都,京都薬科大学愛学館(招待講演)
    • Year and Date
      2011-09-16
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] Take a long-term view (Early Bird Seminar)2011

    • Author(s)
      藤吉好則
    • Organizer
      第34回日本分子生物学会
    • Place of Presentation
      横浜,パシフィコ横浜(招待講演)
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] 電子線結晶学による構造生理学研究2011

    • Author(s)
      藤吉好則
    • Organizer
      構造生物シンポジウム
    • Place of Presentation
      大阪,大阪大学バイオ関連多目的研究施設(招待講演)
    • Year and Date
      2011-03-18
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] Strong Points of Electron Crystallography Shown in Water and Ion Channels2011

    • Author(s)
      Y.Fujiyoshi
    • Organizer
      Gordon Research Conferences (Three Dimensional Electron Microscopy)
    • Place of Presentation
      New London, USA, Colby-Sawyer College(招待講演)
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] Structure and function of water and ion channels2011

    • Author(s)
      Y.Fujiyoshi
    • Organizer
      International Symposium on Bioimaging and Surface Sciences
    • Place of Presentation
      Hyogo (Japan),先端科学技術支援センター(招待講演)
    • Year and Date
      2011-02-27
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] 第33回日本神経科学大会2010

    • Author(s)
      湊原圭一郎、藤吉好則、土井知子
    • Organizer
      Preferable binding of a novel synaptic adhesion molecule, LRRTM2 with SAP102.
    • Place of Presentation
      神戸コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-19300128
  • [Presentation] Structural physiology based on electron crystallography2010

    • Author(s)
      Y.Fujiyoshi
    • Organizer
      The 24th Annual Symposium of The Protein Society
    • Place of Presentation
      La Jolla (USA)(招待講演)
    • Year and Date
      2010-08-01
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] (脳の分子レベルからの理解を目指した)構造生理学の現状と展望2010

    • Author(s)
      藤吉好則
    • Organizer
      生体機能関連若手サマースクール
    • Place of Presentation
      亀山,国民宿舎関ロッジ(招待講演)
    • Year and Date
      2010-07-16
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] Involvement of cytoplasmic construction with aquaporin-4 functions2010

    • Author(s)
      谷一寿, 三潴忠典, 廣明洋子, 亀川亜希子, 鈴木博視, 藤吉好則
    • Organizer
      第48回日本生物物理学会年会
    • Place of Presentation
      東北大学
    • Data Source
      KAKENHI-PROJECT-22770147
  • [Presentation] Structural physiology of ion and water channels based on electron crystallography2010

    • Author(s)
      Y.Fujiyoshi
    • Organizer
      The Third K.H.Kuo Summer School of Electron microscopy and Crystallography "International Workshop of 3D Molecular Imaging Cryo-Electron Microscopy"
    • Place of Presentation
      Beijing (China)(招待講演)
    • Year and Date
      2010-08-10
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] これからの生命科学、数学に求めること2009

    • Author(s)
      藤吉好則
    • Organizer
      RIMS共同研究「離散力学系の分子細胞生物学への応用数理」
    • Place of Presentation
      京都
    • Year and Date
      2009-01-05
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] 膜タンパク質の構造を機能研究の現状2009

    • Author(s)
      藤吉好則
    • Organizer
      三井化学株式会社講演会
    • Place of Presentation
      茂原
    • Year and Date
      2009-01-19
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] 第82回日本生化学会大会2009

    • Author(s)
      奥田明子、西村章子、藤吉好則、土井知子
    • Organizer
      Characterization of hETBR expressed in E.coli for isolation of thermo-stable mutants.
    • Place of Presentation
      神戸コンベンションセンター
    • Data Source
      KAKENHI-PROJECT-19300128
  • [Presentation] 構造生理学研究のための見る技術2009

    • Author(s)
      藤吉好則
    • Organizer
      マイクロビームアナリシス第141委員会第135回研究会
    • Place of Presentation
      東京
    • Year and Date
      2009-03-03
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Structure and function of adhennels : adhesive channels (Invited lecture)2009

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      Network of Excelence-3D-EM Final Meeting
    • Place of Presentation
      Brdo (Slovenia)
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] 第32回日本分子生物学会年会2009

    • Author(s)
      市川昌平、関達也、藤吉好則、土井知子
    • Organizer
      The ligand-binding of PDZ domains play different roles in the synaptic clustering of PSD-95 and SAP102.
    • Place of Presentation
      横浜国際会議
    • Data Source
      KAKENHI-PROJECT-19300128
  • [Presentation] 多機能性チャネルを中心とした構造生理学2009

    • Author(s)
      藤吉好則
    • Organizer
      生機能研究科第46回研究交流本フロンティアバイオサイエンスコロキウム
    • Place of Presentation
      大阪
    • Year and Date
      2009-01-14
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] The ligand-binding of PDZ domains play different roles in the synaptic clustering of PSD-95 and SAP1022009

    • Author(s)
      市川昌平, 関達也, 藤吉好則, 土井知子
    • Organizer
      日本分子生物学会
    • Place of Presentation
      横浜国際会議場
    • Year and Date
      2009-12-17
    • Data Source
      KAKENHI-PROJECT-19300128
  • [Presentation] Structure and function of adhennels : adhesive channels2009

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      Network of Excelence-3D-EM Final Meeting
    • Place of Presentation
      Brdo (Slovenia)
    • Year and Date
      2009-02-11
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] 多機能性チャネルの構造生理学2008

    • Author(s)
      藤吉好則
    • Organizer
      特別講演会「今をときめく生命科学 : 如何にして新しい概念を提唱するか」
    • Place of Presentation
      仙台
    • Year and Date
      2008-06-20
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] 電子顕微鏡法の現状と展望2008

    • Author(s)
      藤吉好則
    • Organizer
      Biological Seminar
    • Place of Presentation
      三島
    • Year and Date
      2008-05-22
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Structure and function of Multifunctional channels (Keynote lecture)2008

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      IUCr2008
    • Place of Presentation
      Osaka (JAPAN)
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] 多機能性膜タンパク質の生理的意味2008

    • Author(s)
      藤吉 好則
    • Organizer
      千里ライフサイエンスセミナー<生命機能を支える生体超分子の高次構造と機能>
    • Place of Presentation
      大阪
    • Year and Date
      2008-02-28
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] 構造生理学研究の1例2008

    • Author(s)
      藤吉 好則
    • Organizer
      第32回構造生物応用研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-02-21
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] 電子顕微鏡を機軸とした構造生理学2008

    • Author(s)
      藤吉好則
    • Organizer
      松下電器産業株式会社講演会
    • Place of Presentation
      京都
    • Year and Date
      2008-07-28
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Structure and Function of Multifunctional Channels2008

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      Neuroscience2008
    • Place of Presentation
      Tokyo (Japan)
    • Year and Date
      2008-07-10
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Introduction to cryo-electron microscopy2008

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      Beijing Workshop of Cryo-Electron Microscopy in Structural Biology
    • Place of Presentation
      Beijing (China)
    • Year and Date
      2008-07-14
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] 電子顕微鏡による膜タンパク質の構造解析2008

    • Author(s)
      藤吉 好則
    • Organizer
      横浜市立大学大学院国際総合科学研究「生体超分子化学講究」
    • Place of Presentation
      横浜
    • Year and Date
      2008-01-15
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Structure and function of Multifunctional Channels2008

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      BMB2008
    • Place of Presentation
      Kobe (Japan)
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] 多機能性チャネルを中心とした構造生理学研究2008

    • Author(s)
      藤吉好則
    • Organizer
      第5回KMU研究推進セミナー
    • Place of Presentation
      金沢
    • Year and Date
      2008-06-26
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Structure and Function of Multifunctional Channels (Special Lecture)2008

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      Neuroscience2008 (The 31st Annual Meeting of the Japan Neuroscience Society)
    • Place of Presentation
      Tokyo (JAPAN)
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] 多機能性チャネルの構造生理学2008

    • Author(s)
      藤吉好則
    • Organizer
      第38回日本免疫学会総会・学術集会
    • Place of Presentation
      京都
    • Year and Date
      2008-12-01
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] 多機能チャネルの構造生理学2008

    • Author(s)
      藤吉 好則
    • Organizer
      「特定領域」マルチスケール操作によるシステム細胞工学(バイオ操作)第5回シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2008-03-07
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Membrane protein structure2008

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      Beijing Workshop of Cryo-Electron Microscopy-in Structural Biology
    • Place of Presentation
      Beijing (China)
    • Year and Date
      2008-07-16
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Structure and function of water and ion channels2008

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      150th anniversary of Japan-France relationship
    • Place of Presentation
      Kyoto (Japan)
    • Year and Date
      2008-11-27
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Structure and function of Multifunctional channels2008

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      IUCr2008
    • Place of Presentation
      Osaka (Japan)
    • Year and Date
      2008-08-26
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Structure and function of Multifunctional Channels2008

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      International Symposium on Integrative Membrane Biology
    • Place of Presentation
      Kobe (Japan)
    • Year and Date
      2008-12-18
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] 構造生理学研究の1例2008

    • Author(s)
      藤吉 好則
    • Organizer
      県立広島大学大学院総合学術研究科生命システム科学特別講義
    • Place of Presentation
      広島
    • Year and Date
      2008-01-30
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] 電子顕微鏡を機軸とした構造生理学2008

    • Author(s)
      藤吉好則
    • Organizer
      日本顕微鏡学会第64回学術講演会
    • Place of Presentation
      京都
    • Year and Date
      2008-05-22
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Structure and function of channels2008

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      Innovation in Diffraction Structural Biology : Neuroscience and electron microscopy
    • Place of Presentation
      Kyoto (Japan)
    • Year and Date
      2008-10-27
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Structure and function of multifunctional channels2007

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      Seminar at CMBN University of Oslo
    • Place of Presentation
      Oslo (Norway)
    • Year and Date
      2007-10-29
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Structure and function of aquaporins (Keynote lecture)2007

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      The 5th International Conference of Aquaporin
    • Place of Presentation
      Nara (JAPAN)
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Structure and function of channels2007

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      Albany 2007: The 15th Conversation
    • Place of Presentation
      Albany (USA)
    • Year and Date
      2007-06-22
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] バイオ研究に生命を吹き込んだ低温観察技術2007

    • Author(s)
      藤吉 好則
    • Organizer
      シンポジウム「科学技術立国の礎」-日本の"見る技術"を再興する-・
    • Place of Presentation
      東京
    • Year and Date
      2007-05-10
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Structure and function of aquaporins2007

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      The 5th International Conference of Aquaporin
    • Place of Presentation
      Nara (Japan)
    • Year and Date
      2007-07-15
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Structural physiology of multifunctional channels (Keynote lecture)2007

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      Joint International Symposium "Membrane Transport as a universal Biological mechanism"
    • Place of Presentation
      Kyoto (JAPAN)
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Structural physiology of multifunctional channels = Struggling to study brain functions=2007

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      Max-Planck-Institut fur Biochemie, Moleculare Strukturbiologie
    • Place of Presentation
      Martinsried (Germany)
    • Year and Date
      2007-10-10
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Specimen preparation techniques for high resolutionstructural studies by cryo-EM2007

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      Workshop on advanced Topics in EM Structure Determination
    • Place of Presentation
      La Jolla (USA)
    • Year and Date
      2007-11-11
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Structure and function of cell adhesive2006

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      5th International NCCR Symposium on New Trends in Structural Biology
    • Place of Presentation
      Zurich (SWITZERLAND)
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Structure and function of water channels2005

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      4th World Congress of Cellular and Molecular Biology
    • Place of Presentation
      Poitiers (FRANCE)
    • Year and Date
      2005-10-09
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Structure and function of various water channels (Keynote Lecture)2005

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      The 2nd Bilateral Japan-UK Symposium on Structural Genomics and Proteomics
    • Place of Presentation
      Yokohama (JAPAN)
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Structure and gating mechanism of the acetylcholine receptor2004

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      The 77th Annual Meeting of the Japanese Biochemical Society
    • Place of Presentation
      Yokohama (JAPAN)
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Structure and function of channels observed through an electron beam (Special Lecture)2004

    • Author(s)
      Y. Fujiyoshi
    • Organizer
      16th International Congress of the IFAA Anatomical Science 2004 -From Gene to Body-
    • Place of Presentation
      Kyoto (JAPAN)
    • Data Source
      KAKENHI-PROJECT-16001005
  • [Presentation] Structural Physiology of Adhennels

    • Author(s)
      藤吉 好則
    • Organizer
      The 45th NIPS International Symposium
    • Place of Presentation
      生理学研究所
    • Year and Date
      2014-11-25 – 2014-11-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] Structural physiology studied by cryo-electron microscopy

    • Author(s)
      藤吉 好則
    • Organizer
      日本解剖学回総会/日本生理学会大会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2015-03-21 – 2015-03-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] Structures of cell adhesive-channels

    • Author(s)
      藤吉 好則
    • Organizer
      16th International Conference on Retinal Proteins
    • Place of Presentation
      長浜ロイヤルホテル
    • Year and Date
      2014-10-05 – 2014-10-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-22227004
  • [Presentation] 構造生理学と創薬科学研究

    • Author(s)
      藤吉 好則
    • Organizer
      新学術領域研究「天然物ケミカルバイオロジー~分子標的と活性制御~」第6回公開シンポジウム
    • Place of Presentation
      名古屋大学
    • Year and Date
      2014-05-28 – 2014-05-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-22227004
  • []

  • []

  • []

  • []

  • []

  • []

  • 1.  ABE Kazuhiro (60596188)
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  • 26.  ISHIZUKA K. (40135596)
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  • 27.  KOBAYASHI T. (50027059)
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  • 31.  入江 克雅 (20415087)
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  • 38.  ODA Yukako
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  • 39.  長田 重一
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  • 40.  原田 哲仁
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