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Aigaki Toshiro  相垣 敏郎

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… Alternative Names

相垣 敏郎  アイガキ トシロウ

AIGAKI Toshiro  相垣 敏郎

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Researcher Number 80150879
Other IDs
External Links
Affiliation (Current) 2025: 東京都立大学, 理学研究科, 特任教授
Affiliation (based on the past Project Information) *help 2014 – 2015: 首都大学東京, 理工学研究科, 教授
2008 – 2011: Tokyo Metropolitan University, 大学院・理工学研究科, 教授
2007: Tokyo Metropolitan University, 大学院・ 理工学研究科, 教授
2006: 首都大学東京, 理工学研究科, 教授
2005: 首都大学東京, 都市教養学部理工学系, 教授
2004: 東京都立大学, 助教授
1999 – 2004: 東京都立大学, 理学研究科, 助教授
Review Section/Research Field
Principal Investigator
Biological Sciences / Animal physiology/Animal behavior
Keywords
Principal Investigator
ショウジョウバエ / 強制発現ベクター / 表現型情報 / GAL4-UASシステム / GSベクター / GS系統 / Gene Searchシステム / 強制発現変異体 / 強制発現システム / データベース … More / ゲノム / 寿命 / エピジェネティクス / 生殖力 / エビジェネティスク / 遺伝子発現 / メタボローム / 貧栄養培地 / 長寿命系統 / 寿命の進化 / Phenotvpic information / GAL4-UAS system / GS vector / GS line / Gene Search system / misexpression phenotype / misexpression vector / Drosophila / エンハンサートラップ / 機能ゲノミクス / 機能獲得変異体 / 酸化ストレス耐性 / Cre-loxPシステム / 強制発現 / 突然変異体 / 選択的スプライシング / ゲノム配列 / LM-PCR / ショウジョバエ / 生物発光 / 発光レポーター / 遺伝子ターゲティング / カルシニューリン / カルシウムシグナル / 活性化 / 減数分裂 / 卵細胞 / カスパーゼシグナリング / インスリンシグナリング / 翅 / 遺伝子強制 / ライブイメージング / 組織サイズ / 画像データ / ストレス感受性 / 形態 / RNAi / 遺伝子強制発現 / 表現型 / 遺伝子 / 温度感受性変異体 / 発生 / 老化 Less
  • Research Projects

    (5 results)
  • Research Products

    (111 results)
  • Co-Researchers

    (3 People)
  •  新規に樹立した長寿命ショウジョウバエを用いた個体老化機構の解明Principal Investigator

    • Principal Investigator
      相垣 敏郎
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Research Field
      Animal physiology/Animal behavior
    • Research Institution
      Tokyo Metropolitan University
  •  ショウジョウバエ卵細胞における減数分裂制御シグナルの解明Principal Investigator

    • Principal Investigator
      相垣 敏郎
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan University
  •  Systems genomics in DrosophilaPrincipal Investigator

    • Principal Investigator
      AIGAKI Toshiro
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Tokyo Metropolitan University
  •  SYSTEMATIC FUNCTIONAL ANALYSES OF GENES IN THE DROSOPHILA GENOMEPrincipal Investigator

    • Principal Investigator
      AIGAKI Toshiro
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      TOKYO METROPOLITAN UNIVERSITY
  •  ショウジョウバエの寿命を制御する因子の探索Principal Investigator

    • Principal Investigator
      相垣 敏郎
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Tokyo Metropolitan University

All 2014 2013 2012 2010 2009 2008 2007 2006 2005 2004 2003 2002 2001 Other

All Journal Article Presentation Book Patent

  • [Book] 考化・老年病研究のための動物実験ガイドブック (日本基礎老化学会編) ショウジョウバエモデル2008

    • Author(s)
      相垣敏郎
    • Publisher
      アドスリー丸善
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Book] 老化・老年病研究のため動 物実験ガイドブック72-77ショウジョウバエモデル(日本基礎老化学)2008

    • Author(s)
      相垣敏郎
    • Publisher
      丸善
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] Shaggy/glycogen synthase kinase 3β and phosphorylation of Sarah/regulator of calcineurin are essential for completion of Drosophila female meiosis2012

    • Author(s)
      Takeo S, Swanson SK, Nandanan K, Nakai Y, Aigaki T, Washburn MR, Florens L, Hawley RS
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: (in press) Issue: 17 Pages: 6382-6389

    • DOI

      10.1073/pnas.1120367109

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22019029
  • [Journal Article] Calcineurin and its regulation by Sra/RCAN is required for completion of meiosis in Drosophila.2010

    • Author(s)
      Takeo S, Hawley RS, Aigaki T.
    • Journal Title

      Dev Biol

      Volume: 344 Pages: 957-967

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22019029
  • [Journal Article] Overexpression of grappa encoding a histone methyltransferase enhances stress resistance in Drosophila2009

    • Author(s)
      Olivier, L., Togawa, T., Tsuda, M., Matsuo, T., Loic, E., Aigaki, T.
    • Journal Title

      Hereditas 146

      Pages: 19-28

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] The Drosophila TRPA channel, Painless, regulates sexual receptivity in virgin females.2009

    • Author(s)
      Sakai, T., Kasuya, J., Kitamoto, T., Aigaki, T
    • Journal Title

      Genes Brain Behay. 8

      Pages: 546-557

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] Mitochondrial Protein Preli-like Is Required for Development of Dendritic Arbors and Prevents Their Regression in the Drosophila Sensory Nervous System.2009

    • Author(s)
      Tsubouchi, A., Tsuyama, T., Fujioka, M., Kohda, H., Okamoto-Furuta, K., Aigaki, T., Uemura, T.
    • Journal Title

      Development 136

      Pages: 3757-3766

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] Overexpression of grappa encoding a histone methyltransferase enhances stress resistance in Drosophila2009

    • Author(s)
      List O, Togawa T, Tsuda M, Matsuo T, Elard L, Aigaki T
    • Journal Title

      Hereditas 146(1)

      Pages: 19-28

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] The Drosophila TRPA channel, Painless, regulates sexual receptivity in virgin females.2009

    • Author(s)
      Sakai, T., Kasuya, J., Kitamoto, T., Aigaki, T.
    • Journal Title

      Genes Brain Behav. 8

      Pages: 546-557

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] Aberrant E2F activation by polyglutamine expansion of androgen receptor in SBMA neurotoxicity.2009

    • Author(s)
      Suzuki, E., Zhao Y., Ito, S., Sawatsubashi, S., Murata, T., Furutani, T., Shirode, Y., Yamagata, K., Tanabe, M., Kimura, S., Ueda, T., Fujiyama, S., Lim, J., Matsukawa, H., Kouzmenko, AP., Aigaki, T., Tabata, T., Takeyama, KI., Kato, S.
    • Journal Title

      Proc Natl Acad Sci USA. 106

      Pages: 3818-3822

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] a Drosophila melanogaster 5'-end mRNA transcription database2009

    • Author(s)
      Ahsan, B., Saito, TL., Hashimoto, S., Muramatsu, K., Tsuda, M., Sasaki, A., Matsushima, K., Aigaki, T., Morishita, S.
    • Journal Title

      Nucleic Acids Res. 37

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] Protein kinase A inhibits a consolidated form of memory in Drosophila2008

    • Author(s)
      Horiuchi, J., Yamazaki, D., Naganos, S., Aigaki, T., Saitoe, M.
    • Journal Title

      Proc Natl Acad Sci U S A 105

      Pages: 20976-20981

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] Behavioral analyses of mutants for two odorant-binding protein genes, Obp57d and Obp57e, in Drosophila melanogaster.2008

    • Author(s)
      Harada, E., Haba, D., Aigaki, T., Matsuo, T.
    • Journal Title

      Genes Genet Syst 83

      Pages: 257-264

    • NAID

      10024396266

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] Behavioral analyses of mutants for two odorant-binding protein genes, Obp 57d and Obp57e, in Drosophila melanogaster2008

    • Author(s)
      Harada, E. Haba, D., Aigaki, T., Matsuo, T
    • Journal Title

      Genes Genet. Syst 83

      Pages: 257-264

    • NAID

      10024396266

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] Dual function of Src in the maintenance of adherens junction during epithelial morphogenesis2008

    • Author(s)
      Shindo, M., Wada, H., Kaido, M., Tateno, M., Aigaki, T., Tsuda, L., Hayashi, S.
    • Journal Title

      Development 135(7)

      Pages: 1355-64

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] TCA回路を中心とした代謝調節と寿命制御2008

    • Author(s)
      木下善仁, 津田学, 相垣敏郎
    • Journal Title

      基礎老化研究 32

      Pages: 21-23

    • NAID

      10024377815

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] Differential control of cell affinity required for progression and refinement of cell boundary during Drosophila leg segmentation2007

    • Author(s)
      Sakurai, T, K., Kojima, T., Aigaki, T., Hayashi, S.
    • Journal Title

      Developmental Biology

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] Thioredoxin Suppresses Parkin-associated Endothelin Receptor-like Receptor-induced Neurotoxicity and Extends Longevity in Drosophila2007

    • Author(s)
      Umeda-Kameyama Y, Tsuda M, Ohkura C, Matsuo T, Namba Y, Ohuchi Y, Aigaki T
    • Journal Title

      Biol Chem 282

      Pages: 11180-11187

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] Antagonistic roles of Wnt5 and the Drl receptor in patterning the Drosophila antennal lobe.2007

    • Author(s)
      Yao, Y., Wu, Y., Yin, C., Ozawa, R., Aigaki, T., Wouda, R.R., Noordermeer, J.N., Fradkin, L.G., Hing, H.
    • Journal Title

      Nat Neurosci. 10

      Pages: 1423-1432

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] A mev-1-like dominant-negative SdhC increases oxidative stress and reduces lifespan in Drosophila.2007

    • Author(s)
      Tsuda M, Sugiura T, Ishii T, Ishii N, Aigaki T.
    • Journal Title

      Biochem Biophys Res Commun. 363

      Pages: 342-346

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] A mev-l-like dominant-negative SdhC increases oxidative stress and reduces lifespan in Drosophila2007

    • Author(s)
      Tsuda M, Sugiura T, Ishii T, Ishii N, Aigaki T.
    • Journal Title

      Biochem Biophys Res Commun 363

      Pages: 342-346

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] Odorant-binding proteins OBP57d and OBP57e affect taste perception and host-plant preference in Drosophila sechellia.2007

    • Author(s)
      Matsuo, T., Sugaya, S., Yasukawa, J., Aigaki, T., Fuyama, Y.
    • Journal Title

      PLoS Biol. 5

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] Thioredoxin suppresses Parkin-associated Endothelin Receptor-like Recepto-induced neurrotoxicity and extends longevity in Drosophila.2007

    • Author(s)
      Umeda-Kameyama, Y., Tsuda, M., Ohkura, C., Matsuo, T., Namba, Y., Ohuchi, Y., Aigaki, T.
    • Journal Title

      J. Biol. Chem. 282

      Pages: 11180-11187

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] Alternative trans-splicing : a novel mode of pre-mRNA processing.2006

    • Author(s)
      Horiuchi, T., Aigaki, T.
    • Journal Title

      Biol. Cell 98

      Pages: 135-140

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] POSH, a scaffold protein for JNK signaling, binds to ALG-2 and ALIX in Drosophila.2006

    • Author(s)
      Tsuda M, Seong KH, Aigaki T
    • Journal Title

      FEBS Lett 580

      Pages: 3296-3300

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] An unconventional myosin in Drosophila reverses the default handedness in visceral organs.2006

    • Author(s)
      Hozumi S, Maeda R, Taniguchi K, Knanai M, Shirakabe S, Sasamura T, Speder P, Noselli S, Aigaki T, Murakami R, Matsuno K
    • Journal Title

      Nature 440

      Pages: 798-802

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] The calcineurin regulator Sra plays an essential role in female meiosis in Drosophila2006

    • Author(s)
      Takeo, S., Tsuda, M., Akahori, S., Matsuo, T., Aigaki, T.
    • Journal Title

      Current Biology 16

      Pages: 1435-1440

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] An NRSF/REST like repressor downstream of Ebi/SMRTER/Su(H) regulates eye development in Drosophila.2006

    • Author(s)
      Tsuda L, Kaido M, Lim YM, Kato K, Aigaki T, Hayashi S
    • Journal Title

      EMBOJ 25

      Pages: 3191-3202

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] Alternative trans-splicing: a novel mode of pre-mRNA processing.2006

    • Author(s)
      Horiuchi, T., Aigaki, T.
    • Journal Title

      Biol. Cell 98

      Pages: 135-140

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] An NRSF/REST-like repressor downstream of Ebi/SMRTER/Su(H) regulates eye development in Drosophila2006

    • Author(s)
      Tsuda, L., Kaido, M., Young-Mi Lim., Kato, K., Aigaki T., Hayashi, S.
    • Journal Title

      The EMBO Journal 25

      Pages: 3191-3202

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] The calcineurin regulator sra plays an essential role in female meiosis in Drosophila.2006

    • Author(s)
      Takeo S, Tsuda M, Akahori S, Matsuo T, Aigaki T
    • Journal Title

      Curr Biol 16

      Pages: 1435-1440

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] An unconventional myosin in Drosophila reverses the default handedness in visceral organs2006

    • Author(s)
      Hozumi, S., Maeda, R., Taniguchi, K., Kanai, M., Shirakabe, S., Sasamura, T., Speder, P., Noselli, S., Aigaki, T., Murakami, R., Matsuno, K.
    • Journal Title

      Nature 440

      Pages: 798-802

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] POSH, a scaffold protein for JNK signaling, binds to ALG-2 and ALIX in Drosophila2006

    • Author(s)
      Tsuda, M., Seong K. -H., Aigaki, T.
    • Journal Title

      FEBS letters 580

      Pages: 3296-300

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] Alternative trans-splicing : a novel mode of pre-mRNA processing.2006

    • Author(s)
      Horiuchi, T., Aigaki, T.
    • Journal Title

      Biol. Cell 98

      Pages: 135-140

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] IKKεRegulates F Actin Assembly and Interacts with Drosophila IAP1 in Cellular Morphogenesis2006

    • Author(s)
      Oshima, K., Takeda, M., Kuranaga, E., Ueda, R., Aigaki, T., Miura, M., Hayashi, S.
    • Journal Title

      Current Biology 16

      Pages: 1531-1537

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] IKK epsilon regulates F actin assembly and interacts with Drosophila IAP1 in cellular morphogenesis.2006

    • Author(s)
      Oshima K, Takeda M, Kuranaga E, Ueda R, Aigaki T, Miura M, Hayashi S
    • Journal Title

      Curr Biol 16

      Pages: 1531-1537

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] A genetic screen for suppressors of Drosophila NSF2 neuromuscular junction overgrowth.2005

    • Author(s)
      Laviolette, M.J., Nunes, N., Peyre, J.B., Aigaki, T., Stewart, B.A.
    • Journal Title

      Genetics 170

      Pages: 779-792

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Expression of a secreted form of Dally, a Drosophila glypican, induces overgrowth phenotype by affecting action range of Hedgehog.2005

    • Author(s)
      Takeo, S., Akiyama, T., Firkus, C., Aigaki, T, Nakato, H.
    • Journal Title

      Dev.Biol, 284

      Pages: 204-218

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] The RING finger-scaffold protein POSH targets TAK1 to control immunity signaling in Drosophila.2005

    • Author(s)
      Tsuda, M., Langmann, C., Harden, N., Aigaki, T.
    • Journal Title

      EMBO reports 6

      Pages: 1082-1087

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] The RING finger-scaffold protein POSH targets TAK1 to control immunity signalling in Drosophila.2005

    • Author(s)
      Tsuda, M., Langmann, C., Harden, N., Aigaki, T.
    • Journal Title

      EMBOr 6

      Pages: 1082-1087

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Expression of a secreted form of Dally, a Drosophila glypican, induces overgrowth phenotype by affecting action range of Hedgehog.2005

    • Author(s)
      Takeo, S., Akiyama, T., Firkus, C., Aigaki, T., Nakato, H.
    • Journal Title

      Dev. Biol. 284

      Pages: 204-218

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] Involvement of winged eye encoding a chromatin-associated bromo-adjacent homology domain protein in disc specification.2005

    • Author(s)
      Katsuyama T., Sugawara, T., Tatsumi, M., Oshima, Y., Gehring, W., Aigaki, T., Kurata, S.
    • Journal Title

      Proc.Natl.Acad.Sci.USA 102

      Pages: 15918-15923

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] A Genetic screen for suppressors of Drosophila NSF2 neuromuscular junction overgrowth2005

    • Author(s)
      Laviolette, M.J., Nunes, N., Peyre, J.B., Aigaki, T., Stewart, B.A.
    • Journal Title

      Genetics 170

      Pages: 779-792

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] A Genetic screen for suppressors of Drosophila NSF2 neuromuscular junction overgrowth.2005

    • Author(s)
      Laviolette M.J., Nunes, N., Peyre, J.B., Aigaki, T., Stewart, B.A.
    • Journal Title

      Genetics 170

      Pages: 779-792

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] Involvement of winged eye encoding a chromatin-associated bromo-adjacent homology domain protein in disc specification.2005

    • Author(s)
      Katsuyama, T., Sugawara, T., Tatsumi, M., Oshima, Y., Gehring, W., Aigaki, T., Kurata, S.
    • Journal Title

      Proc. Natl. Acad. Sci. USA 102

      Pages: 15918-15923

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] Expression of a secreted form of Dally, a Drosophila glypican, induces overgrowth phenotype by affecting action range of Hedgehog.2005

    • Author(s)
      Takeo, S., Akiyama, T., Firkus, C., Aigaki, T., Nakato, H.
    • Journal Title

      Dev. Biol. 284

      Pages: 204-218

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] The slender lobes gene, identified by retarded mushroom body development, is required for proper nucleolar organization in Drosophila.2005

    • Author(s)
      Orihara-Ono, M., Suzuki, M., Saito, M., Yoda, Y., Aigaki, T., Hama, C.
    • Journal Title

      Dev. Biol. 281

      Pages: 121-133

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Gain-of-function screen identifies a role of the Sec6lalpha translocon in Drosophila postmitotic neurotoxicity.2005

    • Author(s)
      Kanuka, H., Hiratou, T., Igaki, T., Kanda., H., Kuranaga, E., Sawamoto, K., Aigaki, T., Okano, H., Miura, M.
    • Journal Title

      Biochim. Biophys. Acta 1726

      Pages: 225-237

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Drosophila orthologues of human b-secretase induce the secretion of a Golgi-resident transferase, heparan sulfate 6-O-sulfotransferase.2005

    • Author(s)
      Kotani, N., Kitazume, S., Kamimura, K., Takeo, S., Aigaki, T., Nakato, H., Hashimoto, Y.
    • Journal Title

      J. Biochem. 137

      Pages: 315-322

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] The RING finger-scaffold protein POSH targets TAK1 to control immunity signaling in Drosophila.2005

    • Author(s)
      Tsuda, M., Langmann, C., Harden, N., Aigaki, T.
    • Journal Title

      EMBO reports 6

      Pages: 1082-1087

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] Involvement of winged eye encoding a chromatin-associated bromo-adjacent homology domain protein in disc specification.2005

    • Author(s)
      Katsuyama, T., Sugawara, T., Tatsumi, M., Oshima, Y., Gehring, W., Aigaki, T., Kurata, S.
    • Journal Title

      Proc. Natl. Acad. Sci.USA 102

      Pages: 15918-15923

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] A Genetic screen for suppressors of Drosophila NSF2 neuromuscular junction overgrowth.2005

    • Author(s)
      Laviolette, M.J., Nunes, N., Peyre, J.B., Aigaki, T., Stewart, B.A.
    • Journal Title

      Genetics 170

      Pages: 779-792

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] The slender lobes gene, identified by retarded mushroom body development, is required for proper nucleolar organization in Drosophila2005

    • Author(s)
      Orihara-Ono, M., Suzuki, M., Saito, M., Yoda, Y., Aigaki, T., Hama, C.
    • Journal Title

      Dev. Biol. 281

      Pages: 121-133

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] Gain-of-function screen identifies a role of the Sec61alpha translocon in Drosophila postmitotic neurotoxicity.2005

    • Author(s)
      Kanuka, H, Hiratou, T, Igaki, T, Kanda, H, Kuranaga, E, Sawamoto, K, Aigaki, T, Okano, H, Miura, M.
    • Journal Title

      Biochim. Biophys. Acta 1726

      Pages: 225-237

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] The RING finger-scaffold protein POSH targets TAK1 to control immunity signaling in Drosophila.2005

    • Author(s)
      Tsuda M., Langmann, C., Harden, N., Aigaki, T.
    • Journal Title

      EMBO reports 6

      Pages: 1082-1087

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] Gain-of-function screen identifies a role of the Sec61 alpha translocon in Drosophila postmitotic neurotoxicity.2005

    • Author(s)
      Kanuka, H, Hiratou, T, Igaki T, Kanda, H, Kuranaga, E, Sawamoto, K, Aigaki, T, Okano, H, Miura, M.
    • Journal Title

      Biochim.Biophys.Acta 1726

      Pages: 225-237

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Journal Article] In vivo hyaluronan synthesis by expression of mammalian hyaluronan synthase gene in Drosophila.2004

    • Author(s)
      Takeo S., Fujise, M., Akiyama, T., Habuchi, H., Itano, N., Matsuo, T., Aigaki, T., Kimata, K., Nakato, H.
    • Journal Title

      J. Biol. Chem. 279

      Pages: 18920-18925

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Comparative sequences analysis of a gene-dense region among closely related species of Drosophila melanogaster.2004

    • Author(s)
      Kawahara, Y., Matsuo, T., Nozawa, M., Shin-I, T., Kohara, Y., Aigaki, T.
    • Journal Title

      Genes Genetic Systems 79

      Pages: 351-359

    • NAID

      130000062151

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Comparative sequences analysis of a gene-dense region among closely related species of Drosophila melanogaster.2004

    • Author(s)
      Kawahara, Y, Matsuo, T., Nozawa, M., Shin-I, T., Kohara, Y., Aigaki, T.
    • Journal Title

      Gen Genet. Sys. 79

      Pages: 351-359

    • NAID

      130000062151

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Genetic Bases of Oxidative Stress Resistance and Life span in Drosophila.2004

    • Author(s)
      Aigaki, T., Kaneuchi, T., Matsuo, T., Seong, K-H., Togawa, T.
    • Journal Title

      J. Clin. Biochem. Nut. 34

      Pages: 77-83

    • NAID

      130003670596

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Expression level of sarah, a homolog of DSCR1 is critical for ovulation and female courtship behavior in Drosophila melanogaster.2004

    • Author(s)
      Ejima, A., Tsuda, M., Takeo, S., Ishii, K., Matsuo, T., Aigaki, T.
    • Journal Title

      Genetics 168

      Pages: 2077-2087

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Genetic Bases of Oxidative Stress Resistance and Life span in Drosophila.2004

    • Author(s)
      Aigaki, T., et al.
    • Journal Title

      J.Clin.Biochem.Nut. 34

      Pages: 77-83

    • NAID

      130003670596

    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Formin 3 is required for assembly of the F-actin structure that mediates tracheal fusion in Drosophila.2004

    • Author(s)
      Tanaka, H., Takasu, E., Aigaki, T., Kato, K., Hayashi, S., Nose, A.
    • Journal Title

      Devel. Biol. 274

      Pages: 413-425

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Drosophila Nedd4 regulates endocytosis of Notch and suppresses its ligand-independent activation.2004

    • Author(s)
      Sakata, T., Sakaguchi, H., Tsuda, L., Higashitani, A., Aigaki, T.; Matsuno, K., Hayashi, S.
    • Journal Title

      Curr. Biol. 14

      Pages: 2228-2236

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Alternative trans-splicing of constant and variable exons of a Drosophila axon guidance gene, lola.2003

    • Author(s)
      Horiuchi, T., Giniger, E., Aigaki, T.
    • Journal Title

      Genes & Development 17

      Pages: 2496-2501

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] (2003) Dally regulates Dpp morphogen gradient formation in the Drosophila wing.2003

    • Author(s)
      Fujise, M., Takeo, S., Kamimura, K., Matsuo, T., Aigaki, T., Izumi, S., Nakato, H.
    • Journal Title

      Development 130

      Pages: 151-1522

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Alternative splicing of lola generates 19 transcription factors controlling axon guidance in Drosophila.2003

    • Author(s)
      Goeke, S., Greene, E.A., Grant, P.K., Gates, M.A., Crowner, D., Aigaki, T., Giniger, E.
    • Journal Title

      Nat. Neurosci. 6

      Pages: 917-924

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Efficient method for measurement of H2O2 resistance in Drosophila.2003

    • Author(s)
      Kaneuchi, T., Togawa, T., Matsuo, T., Fuyama, Y., Aigaki, T.
    • Journal Title

      Biogerontology 4

      Pages: 157-165

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Drosophila lola encodes a family of BTB-transcription regulators with highly variable C-terminal domains containing zinc finger motifs.2003

    • Author(s)
      Ohsako, T., Horiuchi, T., Matsuo, T., Komaya, S., Aigaki, T.
    • Journal Title

      Gene 311

      Pages: 59-69

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Alternative trans-splicing of constant and variable exons of a Drosophila axon guidance gene, lola.2003

    • Author(s)
      Horiuchi, T., Giniger, E., Aigaki, T.
    • Journal Title

      Genes Dev. 17

      Pages: 2496-2501

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Alternative splicing of lola generates 19 transcription factors controlling axon guidance in Drosophila.2003

    • Author(s)
      Goeke, S., Greene, E.A., Grant, P.K., Gates, M.A., Crowner, D., Aigaki, T., Giniger, E.
    • Journal Title

      Nature Neuroscience 6

      Pages: 917-924

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] GETDB, a database compiling expression patterns and molecular locations of a collection of Ga14 enhancer traps.2002

    • Author(s)
      Hayashi, S., Ito, K., Sado, Y., Taniguchi, M., Takeuchi, H., Aigaki, T., Matsuzaki, F., Nakagoshi, H., Tanimura, T., Ueda, R., Uemura, T., Yoshihara, M., Goto, S.
    • Journal Title

      Genesis 34

      Pages: 58-61

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Longevity determination genes in Drosophila melanogaster.2002

    • Author(s)
      Aigaki, T., Seong, K.H., Matsuo, T.
    • Journal Title

      Mech.Age.Dev. 123

      Pages: 1531-1541

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Forked end : a novel transmembrane protein involved in neuromuscular specificity in Drosophila identified by gain-of-function screening2002

    • Author(s)
      Umemiya, T., Takasu, E., Takeichi, M., Aigaki, T., Nose, A.
    • Journal Title

      J. Neurobiol. 51

      Pages: 205-214

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Overexpression of a pattern-recognition receptor, peptidoglycan-recognition protein-LE, activates imd/relish-mediated antibacterial defense and prophenoloxidase cascade in Drosophila larvae.2002

    • Author(s)
      Takehana, A., Katsuyama, T., Tamaki, Y., Oshima, Y., Takada, H., Aigaki, T., Kurata, S.
    • Journal Title

      Proc. Natl. Acad. Sci.USA 99

      Pages: 13705-13710

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Eiger, a TNF superfamily ligand that triggers the Drosophila JNK pathway.2002

    • Author(s)
      Igaki, T., Kanda, H., Goto, Y., Kanuka, H., Kuranaga, E.Aigaki, T., Miura, M.
    • Journal Title

      EMBO J. 21

      Pages: 3009-3018

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] The gene search system : its application to functional genomics and a screen for longevity genes in Drosophila melanogaster.2001

    • Author(s)
      Aigaki, T., Ohsako, T., Toba, G., Seong, K.-H., Matsuo, T.
    • Journal Title

      J. Neurogenet. 15

      Pages: 1-10

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] The gene search system : its application to functional genomics and a screen for longevity genes in Drosophila melanogaster.2001

    • Author(s)
      Aigaki, T., Ohsako, T., Toba, G., Seong, K.-H., Matsuo, T.
    • Journal Title

      Journal of Neurogenetics 15

      Pages: 1-10

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Phenotypic association of spontaneous ovulation and sexual receptivity in virgin females of Drosophila melanogaster.2001

    • Author(s)
      Ejima, A., Nakayama, S., Aigaki, T.
    • Journal Title

      Behav. Genet. 31

      Pages: 437-444

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Application of the gene search system to a screen for longevity gene in Drosophila.2001

    • Author(s)
      Seong, K.-H., Ogashiwa, T., Matsuo, T., Fuyama, Y., Aigaki, T.
    • Journal Title

      Biogerontology 2

      Pages: 209-217

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Neural specific overexpression of DPOSH, Drosophila Plenty of SH3s, extends the longevity of adult flies.2001

    • Author(s)
      Seong, K.-H., Matsuo, T., Fuyama, Y., Aigaki, T.
    • Journal Title

      Biogerontology 2

      Pages: 271-281

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Journal Article] Drosophila orthologues of human b-secretase induce the secretion of a Golgi-resident transferase, heparan sulfate 6-O-sulfotransferase.

    • Author(s)
      Kotani, N., Kitazume, S., Kamimura, K., Takeo, S., Aigaki, T., Nakato, H., Hashimoto, Y.
    • Journal Title

      J. Biochem. 137

      Pages: 315-22

    • Data Source
      KAKENHI-PROJECT-17017032
  • [Patent] 生物用小型8連プラスチックセル2006

    • Inventor(s)
      相垣 敏郎
    • Industrial Property Rights Holder
      首都大学東京
    • Filing Date
      2006
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Patent] 遺伝子探索ベクター隣接ゲノム配列の同定方法、及び酸化ストレス感受性変異体2005

    • Inventor(s)
      相垣敏郎
    • Industrial Property Rights Holder
      首都大学東京
    • Industrial Property Number
      2005-324980
    • Filing Date
      2005-11-09
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Patent] 遺伝子探索ベクター隣接ゲノム配列の同定方法、及び酸化ストレス感受性変異体2005

    • Inventor(s)
      相垣敏郎
    • Industrial Property Rights Holder
      首都大学東京
    • Filing Date
      2005-11-09
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Patent] 遺伝子探索ベクター隣接ゲノム配列の同定方法、及び酸化ストレス感受性変異体2005

    • Inventor(s)
      相垣 敏郎
    • Industrial Property Rights Holder
      首都大学東京
    • Industrial Property Number
      2005-324980
    • Filing Date
      2005-11-09
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Patent] 寿命関連遺伝子の探索方法2001

    • Inventor(s)
      相垣敏郎
    • Industrial Property Rights Holder
      科学技術振興機構
    • Industrial Property Number
      2001-378756
    • Filing Date
      2001-12-12
    • Acquisition Date
      2003-06-24
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-12202002
  • [Presentation] A centenary dilemma: Is aging programmed or non-programmed?2014

    • Author(s)
      Lucas Trindade & Toshiro Aigaki
    • Organizer
      第11回日本ショウジョウバエ研究会
    • Place of Presentation
      金沢歌劇座(石川県)
    • Year and Date
      2014-06-04
    • Data Source
      KAKENHI-PROJECT-13F03382
  • [Presentation] A New Perspective for Aging Research2013

    • Author(s)
      Lucas Trindade, Toshiro Aigaki
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸国際展示場
    • Year and Date
      2013-12-03
    • Data Source
      KAKENHI-PROJECT-13F03382
  • [Presentation] Conditional Knock-In Mutagenesis of Calcineurin Genes.2009

    • Author(s)
      Y, Nakai.M, Tsuda.T, Aigaki.
    • Organizer
      第9回日本ショウジョウバエ研究会
    • Place of Presentation
      ヤマハリゾートつま恋
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Presentation] Chemical genetics in Drosophila : development of a versatile culture system and an automated phenotype analysis for a high-throughput sample.2009

    • Author(s)
      Y, Sato.T, Kaneuchi.O, Masuda.K, Muramatsu.M, Tsuda.T, Aigaki
    • Organizer
      第9回日本ショウジョウバエ研究会
    • Place of Presentation
      ヤマハリゾートつま恋
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Presentation] Mutations in Lipoyltrasferase(lipB) exhibits shorten life span and metabolic disorder in Drosophila.2009

    • Author(s)
      Tsuda, M., Y, Kishita. T, Kaneuchi, T, Aigaki
    • Organizer
      JDRC.
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Presentation] Drosophila sex-peptide: functional dissection and evolution.2009

    • Author(s)
      Tsuda, M., T, Aigaki
    • Organizer
      第32回日本分子生物学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Presentation] Mutations in Lipoyltrasferase (lipB) exhibits shorten life span and metabolic disorder in Drosophila.2009

    • Author(s)
      S, Tomioka.J, Yasukawa.T, Aigaki.T, Matsuo
    • Organizer
      第9回日本ショウジョウバエ研究会
    • Place of Presentation
      ヤマハリゾートつま恋
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Presentation] Identification of functionally important amino acids in two odorant-binding proteins, OBP57d and OBP57e.2009

    • Author(s)
      J, Nakagawa.T, Aigaki.T, Matsuo
    • Organizer
      第9回日本ショウジョウバエ研究会
    • Place of Presentation
      ヤマハリゾートつま恋
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Presentation] Role of laccase in cuticle sclerotization.2009

    • Author(s)
      T, Asano.J, Yatsu.K, Kusumoto.T, Aigaki
    • Organizer
      第9回日本ショウジョウバエ研究会
    • Place of Presentation
      ヤマハリゾートつま恋
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Presentation] ショウジョウバエゲノムの改変による寿命遺伝子の探索と解析2009

    • Author(s)
      相垣敏郎
    • Organizer
      日本基礎老化学会
    • Place of Presentation
      東京都健康長寿医療センター
    • Year and Date
      2009-10-31
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Presentation] Inhibiting PKA activity in the mushroom bodies increases memory and may increase synaptic plasticity in Drosophila.2009

    • Author(s)
      J, Horiuchi.D, Yamazaki.T, Aigaki.M, Saitoe
    • Organizer
      第9回日本ショウジョウバエ研究会
    • Place of Presentation
      ヤマハリゾートつま恋
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Presentation] Swagl, a novel gene tahat regulates body size in Drosophila.2009

    • Author(s)
      M, Funakoshi.K, Muramatsu.M, Tsuda.K, Hatsuta.S, Morishita., T, Aigaki
    • Organizer
      第9回日本ショウジョウバエ研究会
    • Place of Presentation
      ヤマハリゾートつま恋
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Presentation] In vitro binding assay of two odorant-binding proteins, OBP57d and OBP57e.2009

    • Author(s)
      E, Harada.T, Aigaki.T, Matsuo
    • Organizer
      第9回日本ショウジョウバエ研究会
    • Place of Presentation
      ヤマハリゾートつま恋
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Presentation] Loss of lipoyltransferase (lipB) disrupts key metabolic pathways for energy production and leads to shortened lifespan in Drosophila.2009

    • Author(s)
      Kishita, Y., Tsuda, M., Aigaki, T.
    • Organizer
      EDRC2009
    • Place of Presentation
      Nice, France
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Presentation] Drosophila sex-peptide : functional dissection and evolution.2009

    • Author(s)
      津田学 相垣敏郎
    • Organizer
      第32回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Presentation] Insulin Degrading Enzyme in Drosophila2008

    • Author(s)
      Kobayashi, T., Tsuda, M., Matsuo, T. and Aigaki, T
    • Organizer
      日本基礎老化学会第31回大会
    • Place of Presentation
      長野県松本市
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Presentation] ショウジョウバエD-WIP機能破壊変異体の作製と表現型の解析2008

    • Author(s)
      宮田直政, 津田学, 家村俊一郎, 夏目徹, 相垣敏郎
    • Organizer
      第31回日本分子生物学会
    • Place of Presentation
      兵庫県神戸市
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Presentation] ショウジョウバエの寿命と体の大きさを制御する新規遺伝子2008

    • Author(s)
      船越政史, 村松圭吾, 津田学, 初田浩志, 森下真一, 相垣敏郎
    • Organizer
      日本基礎老化学会第31回大会
    • Place of Presentation
      長野県松本市
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Presentation] Structures and functional properties of P{GS} vectors and insertions2008

    • Author(s)
      Aigaki T
    • Organizer
      20th European Drosophila Research Conference
    • Place of Presentation
      Vienna,Austria
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Presentation] ショウジョウバエのmRNA転写産物の5末端配列データベース2008

    • Author(s)
      Budrul Ahsan, 橋本真一, 村松圭吾, 津田学, 佐々木惇, 齊藤太郎, 松島綱治, 相垣敏郎, 森下真一
    • Organizer
      第31回日本分子生物学会
    • Place of Presentation
      兵庫県神戸市
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Presentation] Role of Thioredoxin genes in longevity determination in Drosophila2008

    • Author(s)
      Tsuda, M. and Aigaki, T
    • Organizer
      The Japan-Korea Joint Seminar
    • Place of Presentation
      Nagasaki
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Presentation] ショウジョウバエ寿命決定におけるチオレドキシン遺伝子の機能2008

    • Author(s)
      津田学, 大高領介, 相垣敏郎
    • Organizer
      第31回日本分子生物学会
    • Place of Presentation
      兵庫県神戸市
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Presentation] Genes regulating body size, oxidative stress resistance and longevity in Drosophila2008

    • Author(s)
      Aigaki, T., et.al
    • Organizer
      Korea-Japan joint symposium
    • Place of Presentation
      Daegu, Korea
    • Data Source
      KAKENHI-PROJECT-17017032
  • [Presentation] リボ酸転移酵素 (LipB) の機能抑制によるエネルギー代謝の変化と寿命延長効果2008

    • Author(s)
      木下善仁, 津田学, 相垣敏郎
    • Organizer
      日本基礎老化学会第31回大会
    • Place of Presentation
      長野県松本市
    • Data Source
      KAKENHI-PROJECT-17017032
  • 1.  TRINDADE LUCAS
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 2.  HAYASHI Shigeo (60183092)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 9 results
  • 3.  UEDA Ryu (40353429)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results

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