Ohno Naohito 大野尚仁

… Alternative Names

OHNO Naohito 大野尚仁

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Researcher Number	80152213
Other IDs	https://orcid.org/0000-0003-1937-7118
Affiliation (based on the past Project Information) *help	2020: 東京薬科大学, 薬学部, 名誉教授 2018 – 2019: 東京薬科大学, 薬学部, 教授 2016: 東京薬科大学, 薬学部, 教授 2007 – 2013: Tokyo University of Pharmacy and Life Science, 薬学部, 教授 2003 – 2005: 東京薬科大学, 薬学部, 教授 1998 – 1999: 東京薬科大学, 薬学部, 助教授
Review Section/Research Field	Principal Investigator Bacteriology (including Mycology) / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Biological pharmacy Except Principal Investigator Pediatrics / Bacteriology (including Mycology) / Experimental pathology / Biological pharmacy / Chemistry related to living body
Keywords	Principal Investigator NSAIDs / β-グルカン / BRM / βグルカン / 自然免疫 / 細胞壁多糖 / PAMPs / アレルギーモデル / 抗体産生応答 / 炎症応答 … More / 花粉症 / 糖鎖 / 獲得免疫 / スギ花粉 / antibiotics / intestinal bacteria / nitric oxide / liver injury / beta-glucan / sepsis / 敗血症性ショック / 酸化窒素 / 抗生物質 / 腸内細菌 / 一酸化炭素 / 肝障害 / 敗血症 / Macrophage / Interferon-γ / Indomethacin / Lethal toxicity / NSAID / β-glucan / Bグルカン / マクロファージ / インターフェロン / インドメタシン / 致死毒性 / 非ステロイド性抗炎症薬 / 免疫増強薬 / βーグルカン / DBA/2マウス / 抗炎症作用 / 血管炎 / マイクロアレイ / 真菌 / apoptosis / 遺伝子発現 / 肝臓 / dectin-2 / dectin-1 / マンナン / 免疫毒性 / αマンナン / 感染症 / 感染免疫 / PAMP s / 病態モデル / 消化管障害 / マンノプロテイン / ベータグルカン / 病原真菌 … More Except Principal Investigator 血管炎 / QD / MPO-ANCA / MAPK / STAT / CD14 / CAWS / サイトカインプロファイリング / 川崎病 / βグルカン / β-グルカン / TNFノックアウトマウス / NF kappa B / IL-1 beta / TNF alpha / IL-1 / TNF / FK565 / Nod-1 / マウス血管炎 / vasculitis / nephritis / neutrophil / 腎炎 / 好中球 / raft / nitric oxide / cytokine / monoclonal antibody / macrophage / IL-6 / TNFα / LPS / マウスCD14 / ラフト / NO産生 / サイトカイン / 単クローン抗体 / マクロファージ / ＣＡＷＳ / 免疫異常 / サイトカインプロファイル / 川崎病モデル / Innate Immunity / Tumor Necrosis Factor / 遺伝子プロファイリング / 川崎病モデルマウス / βグルカン認識タンパク / 深在性真菌症診断 / イムノクロマト / β-グルカン認識タンパク / 真菌細胞壁 / イムノクロマトグラフィー / ELISA / ss-グルカン認識タンパク / 深在性真菌症 / ss-グルカン / 固相合成 / 免疫 / 多糖 / デクチン1 / グリコシル化 / 糖質 / グリコシル化反応 / オリゴ糖 / デクチン-1 / 自然免疫 / CR3 / dectin-1 / Th2 / アトピー性皮膚炎 / カンジダ Less

Elucidation of adjuvant activity by polysaccharides in Japanese cedar pollenPrincipal Investigator
- Principal Investigator
  
  Ohno Naohito
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Elucidate the mechanism how Kawasaki disease vasculitis occur
- Principal Investigator
  
  Fukazawa Ryuji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nippon Medical School
Elucidation of Kawasaki disease onset mechanism
- Principal Investigator
  
  RYUJI Fukazawa
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nippon Medical School
Characterization of immunotoxicological and immunopathological roles of fungal PAMPsPrincipal Investigator
- Principal Investigator
  
  OHNO Naohito
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Tokyo University of Pharmacy and Life Science
Examination of rapid and easy detection methods for fungal beta-glucans
- Principal Investigator
  
  ADACHI Yoshiyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Tokyo University of Pharmacy and Life Science
Synthesis of ss-glucan oligosaccharides and their biological evaluation
- Principal Investigator
  
  TANAKA Hiroshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Tokyo Institute of Technology
Characterization of dermal allergic murine models induce by repeated application of non protein substance from pathogenic fungi.
- Principal Investigator
  
  ADACHI Yoshiyuki
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Tokyo University of Pharmacy and Life Science
真菌PAMPsによる消化管粘膜バリア機能の損傷機構に関する研究Principal Investigator
- Principal Investigator
  
  大野尚仁
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Tokyo University of Pharmacy and Life Science
In vivo imaging and molecular mechanism analysis at initial phase of vasculitis development
- Principal Investigator
  
  OKAWARA Akiko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  National Institute of Infectious Diseases
The mechanism of liver dysfunction in endogenous septic shock model micePrincipal Investigator
- Principal Investigator
  
  OHNO Naohito
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Tokyo University of Pharmacy and Life Sciences
Study on regulation of inflammatory response by new mooclonal antibody against leukocytes.
- Principal Investigator
  
  YADOMAE Toshiro
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science,School of Pharmacy
Lethal Toxicity of NSAID in BRM Primed MicePrincipal Investigator
- Principal Investigator
  
  OHNO Naohito
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science

[Book] βグルカン結合タンパク質(「βグルカンの基礎と応用」)第2章2010
- Author(s)
  安達禎之(監修:大野尚仁)
- Total Pages
  283
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-22590407
[Book] ssグルカンの基礎と応用-感染、抗がん、ならびに機能性食品へのssグルカンの関与-2010
- Author(s)
  大野尚仁、安達禎之、三浦典子、石橋健一、飛田敏江、山中大輔
- Total Pages
  283
- Publisher
  シーエムシー
- Data Source
  KAKENHI-PROJECT-22590406
[Book] Toxicology of 1 → 3・Beta-Glucans2006
- Author(s)
  Ken-ichi Ishibashi, Yukari Nakagawa, Naohito Ohno, Toshimi Murai
- Total Pages
  17
- Publisher
  CRC Press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590402
[Book] Toxicology of 1 → 3・Beta-Glucans2005
- Author(s)
  Naohito Ohno
- Total Pages
  17
- Publisher
  CRC Press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590402
[Journal Article] スギ花粉内在性β-グルカンによる樹状細胞活性化と花粉アレルゲン特異的抗体産生の促進作用2021
- Author(s)
  安達禎之・菅野峻史・平塚理恵・大野尚仁
- Journal Title
  
  アレルギーの臨床
  
  Volume: 41 Pages: 75-79
- Data Source
  KAKENHI-PROJECT-18K06636
[Journal Article] Latent 1,3-β-D-glucan acts as an adjuvant for allergen-specific IgE production induced by Japanese cedar pollen exposure2021
- Author(s)
  Kanno Takashi、Adachi Yoshiyuki、Ohashi-Doi Katsuyo、Matsuhara Hiroki、Hiratsuka Rie、Ishibashi Ken-ichi、Yamanaka Daisuke、Ohno Naohito
- Journal Title
  
  Allergol. Int.
  
  Volume: 70 Issue: 1 Pages: 105-113
- DOI
  10.1016/j.alit.2020.08.004
- NAID
  130007966804
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06636, KAKENHI-PROJECT-18K06723
[Journal Article] Possibility of Japanese Cedar Pollen Causing False Positives in the Deep Mycosis Test2021
- Author(s)
  Kanno Takashi、Kim Changmin、Yamanaka Daisuke、Ishibashi Ken-ichi、Tanaka Hiroshi、Ohno Naohito、Adachi Yoshiyuki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 4 Pages: 2135-2135
- DOI
  10.3390/ijms22042135
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22791, KAKENHI-PROJECT-18K06636, KAKENHI-PROJECT-18K06723
[Journal Article] Binding Specificity of a New Artificial β-Glucan Recognition Protein and Its Application to β-Glucan Detection in Mushroom Extracts2021
- Author(s)
  Adachi Yoshiyuki、Kanno Takashi、Ishibashi Ken-ichi、Yamanaka Daisuke、Motoi Akitomo、Motoi Masuro、Ohno Naohito
- Journal Title
  
  International Journal of Medicinal Mushrooms
  
  Volume: 23 Issue: 4 Pages: 1-12
- DOI
  10.1615/intjmedmushrooms.2021038074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06636, KAKENHI-PROJECT-18K06723
[Journal Article] Quantification of β-Glucan from Culinary-Medicinal Mushrooms Using Novel Artificial β-Glucan Recognition Protein2020
- Author(s)
  Kanno Takashi、Adachi Yoshiyuki、Ishibashi Ken-ichi、Yamanaka Daisuke、Ohno Naohito
- Journal Title
  
  International Journal of Medicinal Mushrooms
  
  Volume: 22 (3) Issue: 3 Pages: 269-276
- DOI
  10.1615/intjmedmushrooms.2020034003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06636
[Journal Article] スギ花粉に内在するβ-グルカンの自然免疫活性化作用と抗体産生促進作用2020
- Author(s)
  安達禎之、菅野峻史、平塚理恵、大野尚仁
- Journal Title
  
  アレルギーの臨床
  
  Volume: 40（2） Pages: 58-62
- Data Source
  KAKENHI-PROJECT-18K06636
[Journal Article] N-Terminal (1→3)-β-d-Glucan Recognition Proteins from Insects Recognize the Difference in Ultra-Structures of (1→3)-β-d-Glucan2019
- Author(s)
  Adachi Yoshiyuki、Ishii Masaki、Kanno Takashi、Tetsui Junko、Ishibashi Ken-ichi、Yamanaka Daisuke、Miura Noriko、Ohno Naohito
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 (14) Issue: 14 Pages: 3498-3498
- DOI
  10.3390/ijms20143498
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06636, KAKENHI-PROJECT-18K06723
[Journal Article] Characterization of a murine model with arteritis induced by Nod1 ligand, FK565: a comparative study with a CAWS-induced model2017
- Author(s)
  Ohashi, R. Fukazawa, R. Watanabe, M. Hashimoto, K. Suzuki, N. Nagi-Miura, N. Ohno, N. Shimizu, A. Itoh, Y.
- Journal Title
  
  Mod Rheumatol
  
  Volume: 2017 Issue: 6 Pages: 1-19
- DOI
  10.1080/14397595.2017.1287150
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461624, KAKENHI-PROJECT-16K10079
[Journal Article] Etanercept Suppresses Arteritis in a Murine Model of Kawasaki Disease: A Comparative Study Involving Different Biological Agents2013
- Author(s)
  Ohashi R, Fukazawa R, Watanabe M, Tajima H, Ngai-Miura N, Ohno N, Tsuchiya S, Fukuda Y, Ogawa S, Itoh Y
- Journal Title
  
  International Journal of Vascular Medicine
  
  Volume: 2013 Pages: 1-10
- DOI
  10.1155/2013/543141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591587, KAKENHI-PROJECT-23591588
[Journal Article] Detrimental Effects of β(1-3),(1-6)-D-Glucans2011
- Author(s)
  Naohito Ohno
- Journal Title
  
  Biology and Chemistry of Beta Glucan
  
  Volume: 1 Pages: 68-81
- Data Source
  KAKENHI-PROJECT-22590406
[Journal Article] Vasculitis and anaphylactoid shock in mice induced by the polysaccharide fraction secreted into culture supernatants by the fungus Candida metapsilosis2011
- Author(s)
  Rui Tada, Yusuke Takano, Hisashi Murakami, Ken-ichi Ishibashi, Noriko Nagi-Miura, Yoshiyuki Adachi, Naohito Ohno
- Journal Title
  
  Microbiol Immunol
  
  Volume: 55 Issue: 5 Pages: 357-365
- DOI
  10.1111/j.1348-0421.2011.00326.x
- NAID
  10031121478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590406
[Journal Article] β(1,3)Branched Heptadeca-and Linear Hexadeca-saccharides Possessing an Aminoalkyl Group as a Strong Ligand to Dectin-12010
- Author(s)
  田中浩士、河合徹也、安達禎之、大野尚仁、高橋孝志
- Journal Title
  
  Cbem.Commun 42
  
  Pages: 5942-5944
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20550149
[Journal Article] Characterization of rat beta-glucan receptor dectin-12008
- Author(s)
  Kato Yuya, Adachi Yoshiyuki, Ohno Naohito
- Journal Title
  
  Microbiol Immunol. 52巻
  
  Pages: 418-428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590459
[Journal Article] Dissociation of Toll-like receptor 2-mediated innate immune response to Zymosan by organic solvent-treatment without loss of Dectin-1 reactivity2008
- Author(s)
  Ikeda Yoshihiko, Adachi Yoshiyuki, Ishii Takashi, Miura Noriko, Tamura Hiroshi, Ohno Naohito.
- Journal Title
  
  Biol Pharm Bull. 31巻
  
  Pages: 13-18
- NAID
  110006569967
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590459
[Journal Article] Effect of nitric oxide on β-glucan/indomethacin-induced septic shock2005
- Author(s)
  Sachiko Nameda, Maki Saito, Noriko N.Miura, Yoshiyuki Adachi, Naohito Ohno
- Journal Title
  
  Biol. Pharm. Bull 28
  
  Pages: 1254-1258
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590402
[Journal Article] Structure and immunomodulating activity of fungal β-1,3-glucan2005
- Author(s)
  Naohito Ohno
- Journal Title
  
  Dojin News 114
  
  Pages: 1-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590402
[Journal Article] Effect of nitric oxide on β-glucan/indomethacin-induced septic shock2005
- Author(s)
  Sachiko Nameda, Maki Saito, Noriko N.Miura, Yoshiyuki Adachi, Naohito Ohno
- Journal Title
  
  Biol.Pharm.Bull. 28
  
  Pages: 1254-1258
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590402
[Journal Article] 真菌β-1, 3-グルカン類の構造と宿主応答性2005
- Author(s)
  大野尚仁
- Journal Title
  
  Dojin News 114
  
  Pages: 1-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590402
[Journal Article] Effect of Nitric Oxide on β-Glucan/Indomethacin-Induced Septic Shock2005
- Author(s)
  Sachiko Nameda, Maki Saito, Noriko N, Miura, Yoshiyuki Adachi, Naohito Ohno
- Journal Title
  
  Biol.Pharm.Bull. 28
  
  Pages: 1254-1258
- Data Source
  KAKENHI-PROJECT-15590402
[Journal Article] Endogenous septic shock by combination of β-glucan and NSAIDs2005
- Author(s)
  Naohito Ohno
- Journal Title
  
  Toxicology of 1→3-Beta-Glucans
  
  Pages: 143-159
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590402
[Journal Article] Particulate and soluble β-glucans from Candida albicans modulate cytokine release from human leukocytes2005
- Author(s)
  Ken-ichi Ishibashi, Yukari Nakagawa, Naohito Ohno, Toshimi Murai
- Journal Title
  
  Toxicology of 1→3-Beta-Glucans
  
  Pages: 161-177
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590402
[Patent] β-グルカン結合タンパク質、β-グルカン検出キット、人工DNAおよび細菌2019
- Inventor(s)
  安達禎之, 大野尚仁, 元井益郎, 元井章智
- Industrial Property Rights Holder
  安達禎之, 大野尚仁, 元井益郎, 元井章智
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-107248
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18K06636
[Patent] β-1,3-1,6-グルカンの測定方法2019
- Inventor(s)
  中田秀孝, 安達禎之, 石橋健一, 山中大輔, 大野尚仁
- Industrial Property Rights Holder
  中田秀孝, 安達禎之, 石橋健一, 山中大輔, 大野尚仁
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-209679
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18K06636
[Presentation] Latent 1,3-β-D-glucan in Japanese cedar pollen facilitated allergen-specific IgE production2020
- Author(s)
  Takashi Kanno, Yoshiyuki Adachi, Katsuyo Ohashi-Doi, Hiroki Matsuhara, Rie Hiratsuka, Yoichiro Iwakura, Daisuke Yamanaka, Ken-Ichi Ishibashi, Naohito Ohno
- Organizer
  EAACI Annual Congress 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06636
[Presentation] Latent 1,3-β-D-glucan acts as an adjuvant for allergen-specific IgE production induced by Japanese cedar pollen exposure2020
- Author(s)
  Takashi Kanno, Yoshiyuki Adachi, Katsuyo Ohashi-Doi, Hiroki Matsuhara, Rie Hiratsuka, Ken-ichi Ishibashi, Daisuke Yamanaka, and Naohito Ohno
- Organizer
  JSA/WAO XXVII World Allergy Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06636
[Presentation] 1,3-β-glucan in the Japanese ceder pollen activates innate immune response via dectin-12020
- Author(s)
  Y. Adachi, T. Kanno, K. Ohashi-doi, H. Matsuhara, R. Hiratsuka, K.Ishibashi, D. Yamanaka, N. Ohno
- Organizer
  EAACI Annual Congress 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06636
[Presentation] スギ花粉によるDectin-1を介した樹状細胞成熟化への影響の検討2020
- Author(s)
  金昌ミン、菅野峻史、安達禎之、山中大輔、石橋健一、岩倉洋一郎、大野尚仁
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18K06636
[Presentation] スギ花粉中のβ-1,3-glucan局在と自然免疫賦活化作用2019
- Author(s)
  菅野峻史、安達禎之、平塚理恵、岩倉洋一郎、大野尚仁
- Organizer
  第68回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-18K06636
[Presentation] スギ花粉中1,3-β-glucanによる抗原特異的免疫グロブリン産生誘導作用2019
- Author(s)
  菅野　峻史、安達　禎之、土井　雅津代、松原　弘季、平塚理恵、岩倉　洋一郎、山中　大輔、石橋　健一、大野　尚仁
- Organizer
  第31回日本比較免疫学会学術集会－第30回日本生体防御学会学術総会の合同集会
- Data Source
  KAKENHI-PROJECT-18K06636
[Presentation] Candida Albicans Water Soluble Fractionによるマウス川崎病血管炎モデルにおいて Tumor Necrosis Factor Alphaは中心的役割を果たす2016
- Author(s)
  鈴木伸子, 深澤隆治, 橋本佳亮, 渡邉誠, 赤尾見春、上砂光裕, 勝部康弘, 阿部正徳, 三浦典子, 大野尚仁、小川俊一
- Organizer
  第52回日本小児循環器学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2016-07-06
- Data Source
  KAKENHI-PROJECT-26461624
[Presentation] Candida Albicans Water Soluble Fraction(CAWS)血管炎川崎病モデルと川崎病との類似点・相違点の検証2015
- Author(s)
  深澤隆治、渡邉誠、橋本佳昭、池上英、赤尾見春、阿部正徳、上砂光裕、勝部康弘、三浦典子、大野尚人、小川俊一
- Organizer
  第51回日本小児循環器学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-26461624
[Presentation] Comparison of 4 Different Biological Agents for Suppression of Arteritis in a Kawasaki Disease Mouse Model2013
- Author(s)
  Ohashi R, Fukazawa R, Ohno N, Ogawa S
- Organizer
  The 77th Annual Scientific Meeting of the Japan Circulation Society
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591587
[Presentation] Cell-based reporter assay using innate/acquired immune receptors for detecting fungal products2013
- Author(s)
  Y.Adachi, K.Ishibashi, N.Miura, and N.Ohno
- Organizer
  第86回日本細菌学会総会
- Place of Presentation
  幕張メッセ(千葉県)
- Year and Date
  2013-03-18
- Data Source
  KAKENHI-PROJECT-22590407
[Presentation] 川崎病モデルマウス遺伝子解析による川崎病発症機構の解明2012
- Author(s)
  深澤隆治、大野尚仁、三浦典子、渡邉誠、阿部正徳、林美雪、池上英、橋本康司、小川俊一
- Organizer
  第48回日本小児循環器学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23591587
[Presentation] Disruption of actin cytoskeleton enhanced cytokine synthesis of splenocytes stimulated with beta-glucan in vitro2012
- Author(s)
  N.Ohno、A. Shibata、K. Ishibashi、NN. Miura、 Y. Adachi
- Organizer
  18th Congress of the International Society for Human and Animal Mycology
- Place of Presentation
  Berlin、 Germany
- Year and Date
  2012-06-11
- Data Source
  KAKENHI-PROJECT-22590406
[Presentation] Characterization of systemic response of mice to Candida mannoprotein CAWS assessed by gene expression in liver2012
- Author(s)
  Ohmura Takashi, Miura N.Noriko, Ishibashi Ken-ichi, Adachi Yoshiyuki, Suzuki Kazuo, Ohno Naohito
- Organizer
  The Asia Pacific Meeting of Vasculitis and ANCA Workshop 2012
- Place of Presentation
  東京コンファレンスセンター品川(東京都)
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-22590406
[Presentation] 自然免疫系ssグルカン結合タンパクのグルカン構造特異性2012
- Author(s)
  安達禎之,石橋健一,三浦典子,大野尚仁
- Organizer
  第56回日本医真菌学会総会・学術集会
- Place of Presentation
  京王プラザホテル多摩(東京都)
- Year and Date
  2012-11-10
- Data Source
  KAKENHI-PROJECT-22590407
[Presentation] CAWS投与早期における肝臓の遺伝子発現のマウス系統差による比較2011
- Author(s)
  大村崇, 大野尚仁, 安達禎之, 石橋健一, 三浦典子, 村上央
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-30
- Data Source
  KAKENHI-PROJECT-22590406
[Presentation] Candida albicans可溶性多糖画分CAWS投与マウス肝臓における遺伝子発現の網羅的解析2011
- Author(s)
  大野尚仁, 大村崇, 三浦典子, 石橋健一, 安達禎之
- Organizer
  第55回日本医真菌学会学術集会
- Place of Presentation
  椿山荘(東京都)
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-22590406
[Presentation] Augmentation of cytokine synthesis of splenocytes stimulated with soluble ss-Glucan in vitro by inhibiting actin polymerization2011
- Author(s)
  N. Ohno、A. Shibata、TH. Hida、 K.Ishibashi、NN. Miura、Y. Adachi
- Organizer
  IUMS (International Union of Microbiological Societies)
- Place of Presentation
  札幌市
- Year and Date
  2011-09-06
- Data Source
  KAKENHI-PROJECT-22590406
[Presentation] β-グルカンの免疫認識における多様性2011
- Author(s)
  安達禎之、大野尚仁
- Organizer
  β-1,3グルカンとdectin-1の化学生物医学の基礎と応用に関する研究会
- Place of Presentation
  北九州市立大学サテライトキャンパス
- Year and Date
  2011-10-16
- Data Source
  KAKENHI-PROJECT-22590407
[Presentation] Binding specificity of beta-glucan recognition proteins to triple- helical beta-glucans2011
- Author(s)
  Yoshiyuki Adachi, Masaki Ishii, Ken-ichi Ishibashi, Noriko Miura, Mayumi Kanagawa, Yoshiki Yamaguchi, Akihiro Miyanoshita, Taro Imamura, Naohito Ohno
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜 (神奈川県)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22590407
[Presentation] Augmentation of cytokine synthesis of splenocytes stimulated with soluble β-Glucan in vitro by inhibiting actin polymerization2011
- Author(s)
  Naohito Ohno, Asami Shibata, Toshie H Hida, Ken-Ichi Ishibashi, Noriko N Miura, Yoshiyuki Adachi
- Organizer
  IUMS (International Union of Microbiological Societies) 2011
- Place of Presentation
  札幌コンベンションセンター(札幌市)
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PROJECT-22590406
[Presentation] ss-グルカンの免疫認識における多様性2011
- Author(s)
  安達禎之、大野尚仁
- Organizer
  ss-1,3 グルカンと dectin-1 の化学生物医学の基礎と応用に関する研究会
- Place of Presentation
  北九州市立大学サテライトキャンパス(福岡県)
- Year and Date
  2011-10-16
- Data Source
  KAKENHI-PROJECT-22590407
[Presentation] Efficient Synthesis of β(1,3) Oligosaccharides Exhibiting Dectin-1Agonist Activity.2010
- Author(s)
  田中浩士、河合徹也、安達禎之、大野尚仁、高橋孝志
- Organizer
  International Chemical Congress of Pacific Basin Society PACIFICHEM 2010
- Place of Presentation
  Honolulu, Hawaii,USA
- Data Source
  KAKENHI-PROJECT-20550149
[Presentation] 自然免疫活性化作用を有するβグルカン誘導体の合成研究2010
- Author(s)
  河合徹也、田中浩士、安達禎之、大野尚仁、高橋孝志
- Organizer
  第98同有機合成シンポジウム
- Place of Presentation
  早稲田大学国際会議場
- Data Source
  KAKENHI-PROJECT-20550149
[Presentation] β(1,3)グルカン多糖類の合成法の開発2010
- Author(s)
  河合徹也、田中浩士、武内良太、安達禎之、大野尚仁、高橋孝志
- Organizer
  第29回日本糖質学会年会
- Place of Presentation
  飛騨、岐阜
- Data Source
  KAKENHI-PROJECT-20550149
[Presentation] Synthesis ofβGlucan Oligosaccharide Derivatives Activating Innate Immunity2010
- Author(s)
  河合徹也、田中浩士、安達禎之、大野尚仁、高橋孝志
- Organizer
  第25回国際糖質学会
- Place of Presentation
  幕張メッセ国際会議場,千葉
- Data Source
  KAKENHI-PROJECT-20550149
[Presentation] 自然免疫活性化作用を有するβグルカン誘導体の合成研究2010
- Author(s)
  河合徹也、田中浩士、安達禎之、大野尚仁、高橋孝志
- Organizer
  第90回日本化学会年会
- Place of Presentation
  近畿大学、大阪
- Data Source
  KAKENHI-PROJECT-20550149
[Presentation] 自然免疫活性化作用を有するβグルカン誘導体の合成研究2010
- Author(s)
  河合徹也、田中浩士、安達禎之、大野尚仁、高橋孝志
- Organizer
  第98回有機合成シンポジウム
- Place of Presentation
  早稲田大学国際会議場
- Data Source
  KAKENHI-PROJECT-20550149
[Presentation] Innate immune receptors from invertebrate distinguish fine structural difference of beta-glucans2010
- Author(s)
  Masaki Ishii, Yoshiyuki Adachi, Ken-ichi Ishibashi, Noriko Miura, Akihiro Miyanoshita, Taro Imamura, Hiroshi Tamura, Naohito Ohno
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートーアイランド(兵庫県)
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22590407
[Presentation] Gene expression of splenocytes induced by beta-glucan SCG in DBA/2 mice2010
- Author(s)
  TH.Hida、K. Ishibashi、NN. Miura、Y. Adachi、N. Ohno
- Organizer
  14TH INTERNATIONAL CONGRESS OF IMMUNOLOGY
- Place of Presentation
  神戸市
- Year and Date
  2010-08-22
- Data Source
  KAKENHI-PROJECT-22590406
[Presentation] 病原性真菌多糖による皮膚炎増悪作用の解析2009
- Author(s)
  青木厚介、安達禎之、山口敦子、石橋健一、三浦典子、新槇幸彦、大野尚仁
- Organizer
  日本薬学会第129年会
- Place of Presentation
  京都府京都市
- Year and Date
  2009-03-26
- Data Source
  KAKENHI-PROJECT-19590459
[Presentation] 接触性皮膚炎モデルマウスにおける真菌β-グルカンの影響2008
- Author(s)
  青木厚介、安達禎之、大野尚仁
- Organizer
  第52回日本医真菌学会総会
- Place of Presentation
  長崎県長崎市
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-19590459
[Presentation] IgE介在性の脱顆粒反応における真菌β-グルカンの影響2007
- Author(s)
  青木厚介、安達禎之、大野尚仁
- Organizer
  第51回日本医真菌学会総会
- Place of Presentation
  岐阜県高山市
- Year and Date
  2007-11-09
- Data Source
  KAKENHI-PROJECT-19590459
[Presentation] Characterization of mannan structure required for CAWS-vasculitis
- Author(s)
  Ohno N
- Organizer
  IEIIS2012
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-22590406
[Presentation] Disruption of actin cytoskeleton enhanced cytokine synthesis of splenocytes stimulated with beta-glucan in vitro
- Author(s)
  Ohno N
- Organizer
  18th Congress of the International Society for Human and Animal Mycology
- Place of Presentation
  Berlin, Germany
- Data Source
  KAKENHI-PROJECT-22590406

1. ADACHI Yoshiyuki (60222634)

# of Collaborated Projects: 7 results

# of Collaborated Products: 37 results
2. MIURA Noriko (30218036)

# of Collaborated Projects: 5 results

# of Collaborated Products: 9 results
3. RYUJI Fukazawa (80277566)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. OGAWA Shunichi (50194436)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. TANAKA Hiroshi (40334544)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
6. ISHIBASHI Ken-ichi (20453805)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. YADOMAE Toshiro (40057310)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. NAMEDA Sachiko (80339100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. OKAWARA Akiko (30260277)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SUZUKI Kazuo (20192130)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAKAYAMA Toshinori (50237468)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MINAMITANI Haruyuki (70051779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KAMEOKA Yosuke (00224692)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 大橋隆治 (00328783)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 菅野峻史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ohno Naohito 大野 尚仁

OHNO Naohito 大野 尚仁

Research Projects

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Elucidation of adjuvant activity by polysaccharides in Japanese cedar pollenPrincipal Investigator

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Elucidate the mechanism how Kawasaki disease vasculitis occur

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Elucidation of Kawasaki disease onset mechanism

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Characterization of immunotoxicological and immunopathological roles of fungal PAMPsPrincipal Investigator

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Examination of rapid and easy detection methods for fungal beta-glucans

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Synthesis of ss-glucan oligosaccharides and their biological evaluation

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Characterization of dermal allergic murine models induce by repeated application of non protein substance from pathogenic fungi.

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真菌PAMPsによる消化管粘膜バリア機能の損傷機構に関する研究Principal Investigator

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In vivo imaging and molecular mechanism analysis at initial phase of vasculitis development

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The mechanism of liver dysfunction in endogenous septic shock model micePrincipal Investigator

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Study on regulation of inflammatory response by new mooclonal antibody against leukocytes.

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Lethal Toxicity of NSAID in BRM Primed MicePrincipal Investigator

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[Book] βグルカン結合タンパク質(「βグルカンの基礎と応用」)第2章2010

Author(s)

Total Pages

Ohno Naohito 大野尚仁

OHNO Naohito 大野尚仁