HAGINO Akihiko 萩野顕彦

… Alternative Names

萩野顕彦ハギノアキヒコ

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Researcher Number	80156249
Other IDs
Affiliation (Current)	2025: 東北大学, 医学系研究科, 技術補佐員
Affiliation (based on the past Project Information) *help	2016 – 2017: 東北大学, 農学研究科, 助教 2015: 東北大学, 大学院農学研究科, 助教 2014 – 2015: 東北大学, (連合)農学研究科(研究院), 助教 2012: 東北大学, 大学院・農学研究科, 助教 2007 – 2008: Tohoku University, 大学院・農学研究科, 助教 … More 2006: 東北大学, 大学院農学研究科, 助手 2001 – 2004: 東北大学, 大学院・農学研究科, 助手 1999: Department of Agriculture, Tohoku University, Research Associate, 大学院・農学研究科, 助手 1995 – 1998: TOHOKU UNIVERSITY,FACULTY OF AGRICULTURE,RESEARCH ASSOCIATE, 農学部, 助手 1994: 奥羽大学, 歯学部, 助手 1990: 奥羽大学, 歯学部, 助手 Less
Review Section/Research Field	Principal Investigator Applied animal science / Applied animal science / Zootechnical science/Grassland science / Functional basic dentistry Except Principal Investigator Applied animal science / Animal production science / Applied animal science / Zootechnical science/Grassland science / Zootechnical science/Grassland science
Keywords	Principal Investigator IGF-I / 乳腺上皮細胞 / カゼイン / ウシ乳腺上皮細胞 / 成長ホルモン / STAT5 / bovine mammary epithelial cells / IGF / VFA / dexamethasone … More / casein / 乳腺細胞 / 分化 / インスリン / デキサメサゾン / アポトーシス / IGF結合タンパク質 / 増殖 / growth hormone receptor / MAP kinase / growth hormone / ラクトジェニックホルモン / 成長ホルモン受容体 / MAPキナーゼ / IGFBPs / butyric acid / apoptosis / IGFBP / 酪酸 / SHEEP / FOOD INTAKE / INSULIN / GROWTH HORMONE / タンパク質給与 / 飼料 / 十二指腸 / ルーメン / カゼイン給与 / デンプン給与 / ヒツジ / 採食 / differentiation / insulin / prolactin / mammary epithelium / ペプチド / Matrigel / プロラクチン / マトリゲル / デキサメザソン / 家畜生産システム … More Except Principal Investigator VFA / 成長ホルモン / IGF-I / GH / ウシ / 分泌 / 下垂体 / ルーメン / カルシウムイオン / 薬理学 / 遺伝子 / 発現制御 / 畜産学 / 応用動物学 / IGFBP / 脂肪酸受容体 / Ussing chamber method / the method with eventual sacks / M cell / Small intestine / Development of digestive tract / Horseradish peroxidase (HRP) / Abnormal prion protein / Bovine Spongiform Encephalophasy (BSE) / 離乳 / 回腸 / ホルスタイン雄仔ウシ / Horseradish Peroxidase / 牛海綿状脳症<BSE> / HRP吸収機構 / 消化管の発達 / 空腸と回腸 / ウサギ / ホルスタイン子ウシ / Hourseradish Peroxidase (HRP) / Ussing Chamber法 / 反転腸管法 / M細胞 / 小腸 / 消化管の発育 / Horseradish Peroxidase (HRP) / 異常プリオン蛋白質 / 牛海綿状脳症(BSE) / SGLT-1 / Endocrine secretion / Nitrogen metabolism / Glucose metabolism / Rumen-bypass starch / Suckling kids / Suckling calves / 同位元素希釈法 / バイパス澱粉飼料 / 新生子牛 / Na^+グルコーストランスポーター(SGLT-1) / Na^+グルコーストランスポーター1(SGLT-1) / 内分泌 / 窒素代謝 / グルコース代謝 / バイパス澱粉 / 哺乳ヤギ / 哺乳子牛 / milk fatty acids composition / rumen digesta / milk constituents / milk yield / growth hormone / starch / rumen bypass / lactating cow / 血液中ホルモン濃度 / 血液中代謝産物濃度 / 血漿成長ホルモン / 成長ホルモン分泌反応 / 乳中脂肪酸組成 / 第一胃内容物 / 乳成分 / 乳量 / デンプン / ルーメンバイパス / 泌乳牛 / SOMATOTROPHS / GH SECRETING CELLS / GH (GROWTH HORMONE) / GH分泌細胞 / 成長ホルモン(GH) / tyrosine kinase / apoptosis / colostrum / ペプチド / チロシンキナーゼ / アポトーシス / 初乳 / Calcium Current / Calcium Ion / Calcium Channel / Ruminant / Somatotropes / GH Release / GHRP / GRF / ヤギ / カルシウム電流 / ソマトトロフ / カルシウムチャネル / 前葉細胞 / 反芻家畜 / HORMONE / PITUITARY / RUMINANT / RUMEN / 採食 / ヒツジ / ホルモン / 反芻動物 / 脂肪蓄積 / 脂質代謝 / 乳腺細胞 / 肝細胞 / 肝臓組織 / 乳腺組織 / ケメリン / Lactation dairy cattle / Weaning / Chemerin / 脂肪酸合成 / GH分泌 / 不飽和脂肪酸 / インスリン / 脂肪細胞 / 遺伝子多型 / 黒毛和種牛 / 乳腺上皮細胞 / 遺伝子発現 / カゼイン / トリグリセリド / 脂肪酸 / ATP / ウシ乳腺細胞 / タンパク質合成 / 乳腺 / PC12h / Elongation Factor 2 / Protein Kinase Inhibitor / ribosomal proteim S6 / Protein Phosphorylation / Fibroblast Growth Factor / Nerve Growth Factor Less

Study on the development of improvement technology of Japanese Black cattle production selected by GH gene polymorphism
- Principal Investigator
  
  Katoh Kazuo
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Animal production science
- Research Institution
  Tohoku University
The analysis of interaction of chemerin and other adipokines in bovine fat accumulation and lipid metabolim
- Principal Investigator
  
  ROH SANGGUN
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Animal production science
- Research Institution
  Tohoku University
Endocrine and metabolic studies on single nucleotide polymorphism of GH gene in Japanese Black cattle
- Principal Investigator
  
  KATOH Kazuo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Tohoku University
Studies on the mechanism of apoptosis in bovine mammary epithelial cellsPrincipal Investigator
- Principal Investigator
  
  HAGINO Akihiko
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Tohoku University
Mechanism of Prion Protein Absorption from Digestive Tract in Calves
- Principal Investigator
  
  OBARA Yoshiaki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied animal science
- Research Institution
  Tohoku University
Direct effects of growth hormone on the differentiation of bovine mammary epithelial cells.Principal Investigator
- Principal Investigator
  
  HAGINO Akihiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied animal science
- Research Institution
  Tohoku University
クローン化したウシ乳腺上皮細胞へのGH遺伝子導入によるカゼイン生成能促進
- Principal Investigator
  
  加藤和雄
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied animal science
- Research Institution
  Tohoku University
Effects of rumen bypass processed feed on milk yield and growth hormone secretion in lactating cow
- Principal Investigator
  
  HIDARI Hisashi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Zootechnical science/Grassland science
- Research Institution
  Obihiro university of agriculture and veterinary medicine
Promotion of growth rate by improving hormonal and metabolic functions by rumen-bypass starch in suckling calves
- Principal Investigator
  
  OBARA Yoshiaki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied animal science
- Research Institution
  Tohoku University
Studies on the mechanism of apoptosis in bovine mammary epithelial cellsPrincipal Investigator
- Principal Investigator
  
  HAGINO Akihiko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied animal science
- Research Institution
  Tohoku University
Studies on the inhibitory effect of increased VFA concentrations in the rumen after feeding on GH secretion in sheepPrincipal Investigator
- Principal Investigator
  
  HAGINO Akihiko
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied animal science
- Research Institution
  TOHOKU UNIVERSITY
Physiological and molecular biological study on the mechanisms for VFA-induced inhibition of GH release from somatotrophs
- Principal Investigator
  
  KATOH Kazuo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied animal science
- Research Institution
  Tohoku University
Establishment of bovine mammary epithelial cells, an in vitro model for milk protein synthesis.Principal Investigator
- Principal Investigator
  
  HAGINO Akihiko, 佐々木康之
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied animal science
- Research Institution
  Tohoku University
生理活性ペプチドの大量生産に応用可能なウシ乳腺細胞株の開発
- Principal Investigator
  
  SASAKI Yasuyuki
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied animal science
- Research Institution
  Tohoku University
Studies on the action of apoptosis inducing factor derived from bovine colostrum
- Principal Investigator
  
  SASAKI Yasuyuki
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied animal science
- Research Institution
  TOHOKU UNIVERSITY
神経成長因子によってチロシン残基がリン酸化される蛋白質の検索Principal Investigator
- Principal Investigator
  
  萩野顕彦
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Ohu University
CELL-PHYSIOLOGICAL STUDY ON THE INHIBITORY ACTIONS OF VOLATILE FATTY ACIDS ON THE GH RELEASE FORM RUMINANT SOMATOTROPES
- Principal Investigator
  
  KATOH Kazuo
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Applied animal science
- Research Institution
  TOHOKU UNIVERSITY
CONTROL OF PITUITARY HORMONE SECRETION BY RUMINAL VFA IN THE RUMINANT.
- Principal Investigator
  
  SASAKI Yasuyuki
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Applied animal science
- Research Institution
  TOHOKU UNIVERSITY
神経成長因子の作用発現の分子機構
- Principal Investigator
  
  橋本誠一
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Ohu University

All 2012 2009 2007 2005

All Journal Article Presentation

[Journal Article] A high-protein diet induces dissociation between plasma concentrations of growth hormone and ghrelin in wethers2012
- Author(s)
  Takahashi, T., Kobayashi, Y., Haga, S., Ohtani, Y., Sato, K., Obara, Y., Hagino, A., Roh, S.G. and Katoh, K
- Journal Title
  
  Journal of Animal Science
  
  Volume: 90 Pages: 4807-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22380143
[Journal Article] Growth hormone suppresses the expression of IGFBP-5, and promotes the IGF-I-induced phosphorylation of Akt in bovine mammary epithelial cells.2007
- Author(s)
  Sakamoto K, Yano T, Kobayashi T, Hagino A, Aso H, Obara Y.
- Journal Title
  
  Domest Anim Endocrinol. 32(4)
  
  Pages: 260-272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18580263
[Journal Article] Growth hormone acts on the synthesis and secretion of alpha-casein in bovine mammary epithelial cells.2005
- Author(s)
  Sakamoto K, Hagino A, Obara Y. et al.
- Journal Title
  
  Journal of Dairy Research 72
  
  Pages: 1-7
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15580245
[Journal Article] Growth hormone acts on the synthesis and secretion of alpha-casein in bovine mammary epithelial cells2005
- Author(s)
  Sakamoto K, Hagino A, Obara Y.et al.
- Journal Title
  
  Journal of Dairy Research 72
  
  Pages: 1-7
- Data Source
  KAKENHI-PROJECT-15580245
[Journal Article] Growth hormone acts on the synthesis and secretion of alpha-casein in bovine mammary epithelial cells.2005
- Author(s)
  Sakamoto K, Hagino A, Obara Y et al.
- Journal Title
  
  Journal of Dairy Research vol.72
  
  Pages: 1-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15580245
[Presentation] ウシ乳腺上皮細胞およびヒト乳がん細胞の酸化ストレス応答2012
- Author(s)
  萩野顕彦
- Organizer
  日本畜産学会115回大会
- Place of Presentation
  名古屋
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-22380143
[Presentation] ウシ乳腺上皮細胞のIGF結合タンパク質発現に及ぼす催乳ホルモンの影響2009
- Author(s)
  萩野顕彦、大谷喜永、加藤和雄
- Organizer
  日本畜産学会第110回大会
- Data Source
  KAKENHI-PROJECT-18580263

1. KATOH Kazuo (60091831)

# of Collaborated Projects: 12 results

# of Collaborated Products: 1 results
2. SASAKI Yasuyuki (90005637)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. ODA Shinichi (60211827)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. OBARA Yoshiaki (50302196)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. ROH Sang-gun (90322130)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. SANO Hiroaki (20196306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. HIRAYAMA Takuji (00274887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SUZUKI Kei-ichi (10344706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Nakajima Kei-ichi (70362150)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HAGA Satoshi (90442748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HIDARI Hisashi (80003119)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. OHTANI Masayuki (80250538)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 橋本誠一 (60094950)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 斉藤勇 (60083432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 庄司芳男 (60005642)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HAGINO Akihiko 萩野 顕彦

萩野 顕彦 ハギノ アキヒコ

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Direct effects of growth hormone on the differentiation of bovine mammary epithelial cells.Principal Investigator

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Studies on the mechanism of apoptosis in bovine mammary epithelial cellsPrincipal Investigator

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Studies on the inhibitory effect of increased VFA concentrations in the rumen after feeding on GH secretion in sheepPrincipal Investigator

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Establishment of bovine mammary epithelial cells, an in vitro model for milk protein synthesis.Principal Investigator

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HAGINO Akihiko 萩野顕彦

萩野顕彦ハギノアキヒコ