SHINOMIYA Hiroto 四宮博人

… Alternative Names

四宮博人シノミヤヒロト

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Researcher Number	80162618
Other IDs
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Affiliation (Current)	2025: 愛媛県立衛生環境研究所, その他, 所長
Affiliation (based on the past Project Information) *help	2012: 愛媛大学, 医学(系)研究科(研究院), 准教授 2010 – 2011: 愛媛大学, 大学院・医学系研究科, 准教授 2007 – 2008: Ehime University, 大学院・医学系研究科, 准教授 2006: Ehime University, Graduate School of Medicine, Associate Professor, 大学院・医学系研究科, 助教授 2006: 愛媛大学, 大学院医学系研究科, 助教授 … More 1997 – 2005: 愛媛大学, 医学部, 助教授 1992 – 1993: 愛媛大学, 医学部, 講師 1990: Jichi Medical School, Dept. of Microbiology Assistant Professor, 医学部 1989 – 1990: Assistant Professor, Jichi Medical School, 医学部, 講師 1986 – 1987: 自治医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Bacteriology (including Mycology) / Bacteriology (including Mycology) / 細菌学 Except Principal Investigator Immunology / 細菌学 / Bacteriology (including Mycology) / 内科学一般
Keywords	Principal Investigator L-plastin / p65 / 細胞骨格 / 細胞接着 / マクロファージ / 感染防御 / cytoskeleton / アクチン / cell adhesion / リン酸化 … More / plastin / phosphorylation / macrophage / pp65 / プラスチン / p65-scaffold / Toll-like receptor / actin / host defense / Mac-1 / C3H / PP65 / 細菌内毒素(LPS) / protein complex / 接着分子 / 分子集合 / 65 / タンパク複合体 / host dfense / integrin / インテグリン / immunostaining / recombinant protein / P65 / 免疫染色 / リコンビナント蛋白 / splenomegaly / cell adhension / signal transduction / protein phosphorylation / host defnse / アクチン結合蛋白 / 細菌感染 / Plastinイソフォーム / L-Plastin / 脾腫 / 細胞内情報伝達 / タンパク質リン酸化 / protein kinase / motiv sequence / lipopolysaccharide / カルシウム / プロテインキナーゼ / 蛋白質リン酸化反応 / LPS / 癌細胞 / 蛋白質リン酸化酵素 / カゼインキナーゼII / モチーフ配列 / リン酸化反応 / Protein kinase / Plastin / HeJ mouse / Phosphoprotein(pp) / Macrophage / Lipopolysaccharide / 新しい蛋白質 / C3H@HeJマウス / リン酸化蛋白質 / プロテインキナ-ゼ / 遺伝子クロ-ニング / HeJマウス / リン酸化蛋白(PP) / マクロファ-ジ / プロテイン・ナーゼ / C3HIHEJマウス / リン酸化蛋白質(PP) / 炎症 / バクテリアルトランスロケーション / 気道感染 / 細胞間接着 / 日和見原因菌 / 細菌侵入 / 粘膜バリア / action-related protein / NADPH オキシダーゼ / VAV / WASP / アクチン細胞骨格 … More Except Principal Investigator T細胞サブセット / サイトカイン / C3H / LPS / Listeria monocytogenes / リステリア菌 / マクロファージ機能 / IL-12p40 / innate immunity / 感染免疫 / 内毒素 / protein-kinase C / adenylate cyclase / macrophages / interleukin-1 / intracellular signal transmission / immunecompetent cells / mouse / interferon-gamma / プロテイン・カイネ-スC / アデニレ-ド・サイクレ-ス / マクロファ-ジ / インタ-ロイキン-1 / 細胞内シグナル伝達 / 免疫細胞 / マウス / インタ-フェロン-γ / Beige mouse / HeJ mouse / Macrophage-activating factor / Bacterial lipopolysaccharide / Interferon-r / BCG感染 / インターフェロン / ムラミールジペプチド / BCG感作 / beigeマウス / HeJマウス / マクロファージ活性化因子 / 細菌リポ多糖 / インターフェロンγ / T cell subsets / Cytokines / Adaptive immunity / Innate immunity / 獲得免疫 / 自然免疫 / dendritic cell / macrophage / cytokine / IL-12 gene / IRF-1 / 樹状細胞 / マクロファージ / IL-12遺伝子 / macrophage function / IL-12 p40 / T cell subset / infection immunity / pluripotent stem cells / MHC molecules / cell death / immunological tolerance / fractionated irradiation / 多能性幹細胞 / MHC分子 / 細胞死 / 免疫寛容 / 部分放射線照射 / Pseudomonas aeruginosa / Salmonella / Protection against infection / Cytokine / Lipopolysaccharide (LPS) / 菌体成分 / 緑膿菌 / サルモネラ / 感染防御 / LPS(リポ多糖) Less

腸管・気管の粘膜上皮バリアにおける細胞骨格系の重要性とその破綻Principal Investigator
- Principal Investigator
  
  四宮博人
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Ehime University
Analysis of the leukocyte cytoskeletal dynamics that are essential or the host defense mechanisms against infectionsPrincipal Investigator
- Principal Investigator
  
  SHINOMIYA Hiroto
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Ehime University
The host defense mechanism by protein complexes assembling on the p65/L-plastin scaffold.Principal Investigator
- Principal Investigator
  
  SHINNOMIYA Hiroto
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Ehime University
Role of the TLR-pp65-integrin system in host defense against bacterial infectionsPrincipal Investigator
- Principal Investigator
  
  SHINOMIYA Hiroto
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Ehime University
Linkage between innate immunity and adaptive immunity during pahogen infection
- Principal Investigator
  
  ASANO Yoshihiro
- Project Period (FY)
  2002 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Ehime University
The role of proteins belonging to a plastin gene family in host defenses against bacterial infections.Principal Investigator
- Principal Investigator
  
  SHINOMIYA Hiroto
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Ehime University
APPROACHES FOR CONTROLLING INFECTION BY GENE THERAPY
- Principal Investigator
  
  ASANO Yoshihiro
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Immunology
- Research Institution
  EHIME UNIVERSITY
The 2nd pathway of T cell subset differentiation induced by pathogenic infection
- Principal Investigator
  
  ASANO Yoshihiro
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Immunology
- Research Institution
  EHIME UNIVERSITY
Role of pp65/plastin in infection, immunity and oncogenesis.Principal Investigator
- Principal Investigator
  
  SHINOMIYA Hiroto
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Ehime University
MOLECULAR MECHANISM OF THE THIRD TYPE OF CELL DEATH AND ITS APPLICATION FOR SPECIFIC IMMUNOSUPPRESSIVE THERAPY
- Principal Investigator
  
  ASANO Yoshihiro
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  EHIME UNIVERSITY
Analysis of the plastin-pathway involved in macrophage activation.Principal Investigator
- Principal Investigator
  
  SHINOMIYA Hiroto
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  細菌学
- Research Institution
  Ehime University
Production of Cytokines After Stimulation of Bacterial Components And Protective Role of the Cytokines to Bacterial Infection
- Principal Investigator
  
  NAKANO Masayasu
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  細菌学
- Research Institution
  Jichi Medical School
Purification and Characterization of Phosphoproteins which are Induced in Murine Macrophages Stimulated with LPS.Principal Investigator
- Principal Investigator
  
  SHINOMIYA Hiroto
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  細菌学
- Research Institution
  Jichi Medical School
Signal Transmittance on Interferon-gamma-Treated Murine Immunocompetent Cells
- Principal Investigator
  
  NAKANO Masayasu
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for Overseas Scientific Survey.
- Research Institution
  Jichi Medical School
Production and role of Macrophage activating factor (IFN-gamma) by bacterial lipopolysaccharide and other bacterial products
- Principal Investigator
  
  NAKANO Masayasu
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  細菌学
- Research Institution
  Jichi Medical School

All 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003

All Journal Article Presentation

[Journal Article] Plastin Family of Actin-Bundling Proteins : Its Functions in Leukocytes, Neurons, Intestines, and Cancer2012
- Author(s)
  Shinomiya, H.
- Journal Title
  
  Int.J.Cell Biol.
  
  Volume: 2012 Pages: 1-8
- DOI
  10.1155/2012/213492
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590394
[Journal Article] Origins and unconventional behavior of neutrophils in developing zebrafish2008
- Author(s)
  Le Guyader D, Redd MJ, Colucci-Guyon E, Murayama, Shinomiya H, and Herbomel P
- Journal Title
  
  Blood 111
  
  Pages: 132-141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590450
[Journal Article] 宿主防御と病原体感染の攻防の場としての細胞骨格系2007
- Author(s)
  四宮博人
- Journal Title
  
  日本細菌学雑誌 62
  
  Pages: 279-293
- NAID
  10019493500
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590450
[Journal Article] Conformational analysis of the leukocyte-specific EF-hand protein p65/L-plastin by X-ray scattering in solution2007
- Author(s)
  Shinomiya H, Shinjo M, Fengzhi L, Asano Y, Kihara H
- Journal Title
  
  Biophys Chem 131
  
  Pages: 36-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590450
[Journal Article] 宿主防御と病原体感染の攻防の場としての細胞骨格系2007
- Author(s)
  四宮博人
- Journal Title
  
  日本細菌学会誌 62(2)(In press)
- NAID
  10019493500
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590394
[Journal Article] Conformational analysis of the leukocyte-specific EF-hand p65/L-plastin by X-ray scattering in solution2007
- Author(s)
  Shinomiya H, et. al.
- Journal Title
  
  Biophys Chem 131
  
  Pages: 36-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590450
[Journal Article] Dual role of the actin cytoskeleton in host defenses and in the establishment of bacterial infections2007
- Author(s)
  Shinomiya H
- Journal Title
  
  Nippon Saikingaku Zasshi 62
  
  Pages: 279-293
- NAID
  10019493500
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590450
[Journal Article] The dual role of the actin cytoskeleton in hos defenses and in the establishment of bacterial infections.2007
- Author(s)
  Shinomiya, H.
- Journal Title
  
  Jpn J. Bacteriol. 62 (2)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590394
[Journal Article] Generation and Characterization of Monoclonal Antibodies that Specifically Recognize p65/L-Plastin Isoform but not T-Plastin Isoform.2006
- Author(s)
  Toyooka K, Liu F, Ishii M, Saito S, Kirikae T, Asano Y, Shinomiya H.
- Journal Title
  
  Biosci.Biotechnol.Biochem. (in press)
- NAID
  10018530092
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207012
[Journal Article] Analysis of a bacterial lipopolysaccharide-activated serine kinase that phosphorylates p65/L-plastin in macrophages.2006
- Author(s)
  Hagi A, Hirata H, Shinomiya H
- Journal Title
  
  Microbiol.Immunol. 50
  
  Pages: 331-335
- NAID
  10018119296
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207012
[Journal Article] 研究のトピックス : Plastinファミリータンパク質の構造と機能-特に感染防御および細胞悪性化との関連について-2005
- Author(s)
  四宮博人
- Journal Title
  
  愛媛医学 24(4)
  
  Pages: 287-291
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590394
[Journal Article] Structure and function of the plastin protei family-its relevance to host defense and cell maligmancy-.2005
- Author(s)
  Shinomiya, H.
- Journal Title
  
  Ehime M.Journal 24 (4)
  
  Pages: 287-291
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590394
[Journal Article] Characterization of murine grancalcin specifically expressed in leukocytes and its possible role in host defense against bacterial infection.2004
- Author(s)
  Liu F, Shinomiya H, Kirikae T, Hirata H, Asano Y
- Journal Title
  
  Biosci.Biotechnol.Biochem. 68
  
  Pages: 894-902
- NAID
  10013144003
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207012
[Journal Article] X-ray solution scattering study on the leukocyte-specific EF-hand proteins, p65/L-plastin and grancalcin.2004
- Author(s)
  Shinomiya H, Sinjo M, Liu F, Asano Y, Kihara H
- Journal Title
  
  Photon Factory Activity Report 21
  
  Pages: 245-247
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207012
[Journal Article] Identification of IFN regulatory factor-binding site in IL-12 p40 gene promoter.2003
- Author(s)
  Maruyama S, Sumita K, Shen H, Kanoh M, Xu X, Sato M, Matsumoto M, Shinomiya H, Asano Y
- Journal Title
  
  J.Immunol. 170
  
  Pages: 997-1001
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207012
[Journal Article] Preparation and characterization of recombinant marine p65/L-plastin expressed in E.coli and high-titer antibodies against the protein.2003
- Author(s)
  Shinomiya H, Nagai K, Hirata H, Kobayashi N, Hasegawa H, Liu F, Sumita K, Asano Y
- Journal Title
  
  Biosci.Biotechnol.Biochem. 67
  
  Pages: 1368-1375
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14207012
[Journal Article] Preparation and characterization of recombinant p65/L-plastin expressed in E. coil and high-titer antibodies against the protein2003
- Author(s)
  H.Shinomiya, et al.
- Journal Title
  
  Biosci.Biotech.Bichem. 67 (6)
  
  Pages: 1368-1375
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590390
[Journal Article] Preparation and characterization of recombinant murine p65/L-plastin expressed in E.coli and high-titer antibodies against the protein.2003
- Author(s)
  Shinomiya, H., et al.
- Journal Title
  
  Biosic.Biotech.Biochem. 67(6)
  
  Pages: 1368-13675
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590390
[Journal Article] Preparation and characterization of recombinant murine p65/L-plastin expressed in E.coli and high-titer antibodies against the protein.2003
- Author(s)
  Shinomiya T, et al.
- Journal Title
  
  Biosci.Biotechnol.Biochem. 67
  
  Pages: 1368-1375
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14207012
[Presentation] 病院患者および周辺の水系環境から分離された緑膿菌のMultilocus Sequence Typing法による系統解析2012
- Author(s)
  四宮博人
- Organizer
  第85回日本細菌学会総会
- Place of Presentation
  長崎
- Year and Date
  2012-03-27
- Data Source
  KAKENHI-PROJECT-22590394
[Presentation] 愛媛県内の病院および水系環境から分離された緑膿菌のMultilocus Sequence Typing法による系統解析2011
- Author(s)
  四宮博人
- Organizer
  第64回日本細菌学会中国・四国支部総会
- Place of Presentation
  岡山
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-22590394
[Presentation] Pathogenic characterization of P.aeruginosa strains isolated from hospital patients and various aquatic environments : river, coastal areas and the ocean2011
- Author(s)
  Shinomiya, H.
- Organizer
  IUMS2011
- Place of Presentation
  Sapporo, Japan
- Year and Date
  2011-09-10
- Data Source
  KAKENHI-PROJECT-22590394
[Presentation] 緑膿菌のリポ多糖構造の解析とその生態・病原性との関連について2010
- Author(s)
  四宮博人
- Organizer
  第63回日本細菌学会中国四国支部総会
- Place of Presentation
  松山
- Year and Date
  2010-10-16
- Data Source
  KAKENHI-PROJECT-22590394
[Presentation] 緑膿菌の生態・病原性とリポ多糖構造との関連について2010
- Author(s)
  四宮博人
- Organizer
  第19回内毒素・LPS研究会
- Place of Presentation
  横浜
- Year and Date
  2010-06-26
- Data Source
  KAKENHI-PROJECT-22590394
[Presentation] Pseudomonas aeruginosaの環境適応戦略と病原性との関連についての解析2009
- Author(s)
  四宮博人, 野中里佐, 犬伏歩, Nurul Huda Khan, 木暮一啓, 村瀬光春, 鈴木聡, 浅野喜博
- Organizer
  第81回日本細菌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-19590450
[Presentation] 臨床分離緑膿菌と海洋分離緑膿菌の遺伝子型・性状・病原性の比較について2008
- Author(s)
  四宮博人, 他
- Organizer
  第81回日本細菌学会総会
- Place of Presentation
  京都
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19590450
[Presentation] Structure-function analysis of p65/L-plastin that regulates macrophage activities through cytoskeletal remodeling.2008
- Author(s)
  Shinomiya H
- Organizer
  第38回日本免疫学会総会
- Place of Presentation
  京都
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19590450
[Presentation] Structure-function analysis of p65/L-plastin that regulates macrophage activities through cytoskeletal remodeling2008
- Author(s)
  Shinomiya H, Yumoto F, Kirikae T, Matsumoto A, Asano Y
- Organizer
  第38回日本免疫学会総
- Place of Presentation
  京都
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19590450
[Presentation] 臨床分離緑膿菌と海洋分離緑膿菌の遺伝子型・性状・病原性の比較について2008
- Author(s)
  四宮博人, 野中里佐, 木暮一啓, Nurul Huda Khan, 石井良和, 鈴木聡, 浅野喜博
- Organizer
  第8回日本細菌学会総会
- Place of Presentation
  京都
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19590450
[Presentation] Structural and functional analyses of the leukocyte-specific EF-hand protein,p65/L-plastin2007
- Author(s)
  Shinomiya H, et. al.
- Organizer
  第37回日本細菌学会総会
- Place of Presentation
  東京
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19590450
[Presentation] 細菌刺激による白血球細胞骨格再構成とその感染防御における意義2007
- Author(s)
  四宮博人
- Organizer
  第6回四国免疫フォーラム
- Place of Presentation
  愛媛
- Year and Date
  2007-07-14
- Data Source
  KAKENHI-PROJECT-19590450
[Presentation] 自然免疫の基礎免疫学2007
- Author(s)
  四宮博人
- Organizer
  第21回肝類洞壁細胞研究会
- Place of Presentation
  愛媛
- Year and Date
  2007-12-22
- Data Source
  KAKENHI-PROJECT-19590450
[Presentation] Structural and functional analyses of the leukocytespecific EF-hand protein, p65/L-plastin2007
- Author(s)
  Shinomiya H, Yumoto F, Shinjo M, Kihara H, Matsumoto A, Asano Y
- Organizer
  第37回日本細菌学会総会
- Place of Presentation
  京都
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19590450
[Presentation] リステリア感染マクロファージの細胞死誘導機構の解析2007
- Author(s)
  松本哲, 丸山砂穂, 加納誠, 四宮博人, 浅野喜博
- Organizer
  第37回日本細菌学会総会
- Place of Presentation
  京都
- Year and Date
  2007-11-21
- Data Source
  KAKENHI-PROJECT-19590450

1. ASANO Yoshihiro (70114353)

# of Collaborated Projects: 8 results

# of Collaborated Products: 11 results
2. NAKANO Masayasu (70048958)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. TAKI Tatsuo (70049097)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. SUMITA Kohsuke (20281454)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
5. KANOH Makoto (10116923)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
6. KIRIKAE Teruo (50192563)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. NAKANO Yasunobu (70207851)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KUBO Shuichi (00251223)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NAKAYAMA Toshinori (50237468)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MATSUMOTO Akira (90363233)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. MARUYAMA Saho (10301326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. KLEIN Thomas

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SUZUKI Tsuneo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. FRIEDMAN Herman

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. ALFRED Singer

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. RICHARD J. Hodes

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. SINGER Alfre

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. HODES Richar

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHINOMIYA Hiroto 四宮 博人

四宮 博人 シノミヤ ヒロト

Research Projects

Research Products

Co-Researchers

腸管・気管の粘膜上皮バリアにおける細胞骨格系の重要性とその破綻Principal Investigator

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Analysis of the leukocyte cytoskeletal dynamics that are essential or the host defense mechanisms against infectionsPrincipal Investigator

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The host defense mechanism by protein complexes assembling on the p65/L-plastin scaffold.Principal Investigator

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Role of the TLR-pp65-integrin system in host defense against bacterial infectionsPrincipal Investigator

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Linkage between innate immunity and adaptive immunity during pahogen infection

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The role of proteins belonging to a plastin gene family in host defenses against bacterial infections.Principal Investigator

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APPROACHES FOR CONTROLLING INFECTION BY GENE THERAPY

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The 2nd pathway of T cell subset differentiation induced by pathogenic infection

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Role of pp65/plastin in infection, immunity and oncogenesis.Principal Investigator

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MOLECULAR MECHANISM OF THE THIRD TYPE OF CELL DEATH AND ITS APPLICATION FOR SPECIFIC IMMUNOSUPPRESSIVE THERAPY

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Analysis of the plastin-pathway involved in macrophage activation.Principal Investigator

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Production of Cytokines After Stimulation of Bacterial Components And Protective Role of the Cytokines to Bacterial Infection

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Purification and Characterization of Phosphoproteins which are Induced in Murine Macrophages Stimulated with LPS.Principal Investigator

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SHINOMIYA Hiroto 四宮博人

四宮博人シノミヤヒロト