ITOH Hideaki 伊藤英晃

Researcher Number	80168369
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2012 – 2013: 秋田大学, 工学(系)研究科(研究院), 教授 2003 – 2007: Akita University, Faculty of Engineering and Resource Science, Professor, 工学資源学部, 教授 1997 – 2002: 秋田大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator General medical chemistry / Gastroenterology / Nanomaterials/Nanobioscience / Biological Sciences Except Principal Investigator Kidney internal medicine / Cerebral neurosurgery / Gastroenterology / Polymer chemistry / Kidney internal medicine / Chemistry related to living body
Keywords	Principal Investigator 分子シャペロン / 熱ショック蛋白質 / ストレス蛋白質 / Mitochondria / Stress protein / Heat shock protein / Molecular chaperone / ミトコンドリア移行 / シグナルペプチド / ミトコンドリア … More / DNA ポリメラーゼ / DNAポリメラーゼη / 疾患特異マーカー / プロティンチップ / 胃粘膜障害 / 急性腎毒性 / HSP70 / 蛋白質のフォールディング / ポリグルタミン / HSP / シャペロン … More Except Principal Investigator HSP60 / heat shock protein / 分子シャペロン / 熱ショック蛋白質 / TRAIL / SLE / HSPC159 / chemokine ligand 13 / デンドリマー / HSP105 / HSP73 / apoptosis / HSP / DNA / fransfection / electroporation / PC12 / RIP140 / Molecular chaperone / cerebral ischemia / hsp60 / hsp10 / 熱ショック蛋白 / molecular chaperon / 胃潰瘍 / ストレス / 5-HT / TRH / 胃粘膜傷害 / Dendrimer / Biomaterial / Enzymatic Degradation / Nano Materials / 酵素 / 生体材料 / 酵素分解 / ナノ材料 / MPO-ANCA-associated glomeruloneohritis / cDNA microarray / SAGE / MCNS / TNFSF-10 / 寛解・再発 / S100A12 / 末梢単核球 / 高発現遺伝子 / MPO-ANCA関連糸球体腎炎 / cDNA microarray法 / SAGE法 / 微小変化型ネフローゼ症候群 / antigen-antibody interaction / p53 mutant / aromatic polyamide / anti-peptide antibody / dendrimer / ペプチド鎖 / 抗原抗体反応 / 変異p53タンパク質 / 芳香族ポリアミド / ペプチド抗体 / dehydration / renal toxicity / chaperon / gentamicin / heat shock proteins / 浸透圧 / 耐性 / 遺伝子導入 / シャペロン / HSP90 / HSP72 / 脱水 / 腎毒性 / シャペロン活性 / GM / two-hybrid system / humanin / focal segmental glomerulosclerosis / puromycin aminonucleoside / nephrotic syndrome / actinin-4 / filtration barrier / glomerulus / ネフローゼ惹起物質 / two-hybrid法 / ヒューマニン / 巣状分節状糸球体硬化症 / ピューロマイシンアミノヌクレオシド / ネフローゼ症候群 / アクチニン-4 / 濾過バリアー / 糸球体 / gastric mucosal lesion / gastric ulcer / stress / gastric mucosal restoration / gastric mucosal protection / 胃粘膜障害 / 亜鉛 / 粘膜修復 / 消化性潰瘍 / 粘膜防御 / 損傷修復 / 胃粘膜病変 / 胃粘膜修復機構 / 胃粘膜防御機構 / cerehral ischemia / 遺伝子組み換え / トランスフェクション / hsp / transfection / HSP70 / Heat shock protein / 14-3-3 proteins / Mizonbine / Immunosuppressant / HIT蛋白 / 14-3-3蛋白 / SHP60 / ミゾリビン / 免疫抑制剤 / Stress protein / chaperonin / HSP10 / ストレス蛋白 / 脳虚血 / シャペロニン / neuro peptide / gastric mucosal damage / stress protein / NSAID / 神経ペプチド / ストレス蛋白質 Less

Analysis of the cell neoplastic transformation mechanism based on the molecular chaperone HSP90Principal Investigator
- Principal Investigator
  
  ITOH Hideaki
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Akita University
Preparation of Enzyme-Degradable Dendritic Macromolecules
- Principal Investigator
  
  JIKEI Mitsutoshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Polymer chemistry
- Research Institution
  Akita University
Gene expression profiling of peripheral blood mononuclear cells from patients with minimal change nephrotic syndrome
- Principal Investigator
  
  KOMATSUDA Atsushi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Akita University
プロティンチップを用いた疾患特異マーカー検出システムの構築Principal Investigator
- Principal Investigator
  
  伊藤英晃
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  Akita University
Preparation and Immunological Study for Oligopeptide-Dendrimer Conjugates as Multiple Antigen Peptide for p53 Mutant
- Principal Investigator
  
  JIKEI Mitsutoshi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemistry related to living body
- Research Institution
  Akita University
Role of molecular chaperon in gastric mucosal injury and restoration
- Principal Investigator
  
  OTAKA Michiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Akita University
Interaction between glomerular filtration barrier component actinin-4 and nephrosis-inducing factors
- Principal Investigator
  
  WAKUI Hideki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Akita University
Analysis of protective roles for renal injury by heat shock proteins treansfected with HSP genes
- Principal Investigator
  
  KOMATSUDA Atsushi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Akita University
蛋白質のフオールディング異常と神経細胞変性の解析Principal Investigator
- Principal Investigator
  
  伊藤英晃
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Akita University
An analysis of mitochondrial transport mechanisms and physiological functions of mammalian molecular chaperone HSP60Principal Investigator
- Principal Investigator
  
  ITOH Hideaki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  AkitaUniversity
The Investigation of the protective effect of hoat shock protein on neuronal death
- Principal Investigator
  
  KINOUCHI Hiroyuki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Akita University
哺乳動物における分子シャペロンの活性発現機構Principal Investigator
- Principal Investigator
  
  伊藤英晃
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Akita University
A study on an immunosuppressant mizoribine-binding renal proteins (esp. molecular chaperones)
- Principal Investigator
  
  WAKUI Hideki
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Akita University
哺乳類HSPのシャペロン活性発現機構の解析Principal Investigator
- Principal Investigator
  
  伊藤英晃
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Akita University
EXPRESSION AND CYTOPROTECTIVE FUNCTION OF HEAT SHOCK PROTEINS IN THE GASTRIC MUCOSA MEDIATED BY CENTRAL NERVOUS SYSTEM-RELATED NEUROPEPTIDES.
- Principal Investigator
  
  OTAKA Michiro
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Akita University
The expiession and function of molecular chaperone in the central nervous system.
- Principal Investigator
  
  KINOUCHI Hiroyuki
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  AKITA UNIVERSITY
ミュータントHSPを用いたストレス蛋白質のシャペロン活性発現機構の解析Principal Investigator
- Principal Investigator
  
  伊藤英晃
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Akita University

All 2013 2006 2005 2004 2002

All Journal Article Presentation

[Journal Article] Cisplatin binding and inactivation of mitochondrial glutamate oxaloacetate transaminase in cisplatin-induced rat nephrotoxicity2013
- Author(s)
  Taku Ozaki, Sei-ichi Ishiguro, Hideaki Itoh, Kazuhisa Furuhama, Mitsuru Nakazawa, Tetsuro Yamashita
- Journal Title
  
  Bioscience Biotechnology and Biochemistry
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659357
[Journal Article] Zinc-L-Carnosine Binds to Molecular Chaperone HSP70 and Inhibits the Chaperone Activity of the Protein2013
- Author(s)
  Asami Haga, Tomoya Okamoto, Ewa Grave, Hideaki Itoh
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659357
[Journal Article] Over-expression of 70-kDa heat shock protein confers protection against monochloramine-induced gastric mucosal cell injury.2006
- Author(s)
  Oyake J, Otaka M, Matsuhashi T, Jin M, Odashima M, Komatsu K, Wada I, Horikawa Y, Ohba R, Hatakeyama N, Itoh H, Watanabe S.
- Journal Title
  
  Life Sci. (in press)
- Data Source
  KAKENHI-PROJECT-16651056
[Journal Article] Electrochemical polymerization of pyrrole in supercritical carbon dioxide-water emulsion.2006
- Author(s)
  Jikei M, Saitoh S, Yasuda H, Itoh H, Sone M, Kakimoto M, Yoshida H
- Journal Title
  
  Polymer 47
  
  Pages: 1547-1554
- Data Source
  KAKENHI-PROJECT-16651056
[Journal Article] ATP-sensitive K+-channel subunits on the mitochondria and endoplasmic reticulum of rat cardiomyocytes.2005
- Author(s)
  Zhou M, Tanaka O, Sekiguchi M, He HJ, Yasuoka Y, Itoh H, Kawahara K, Abe H.
- Journal Title
  
  J Histochem Cytochem. 53(12)
  
  Pages: 1491-1500
- Data Source
  KAKENHI-PROJECT-16651056
[Journal Article] 哺乳類分子シャペロンの作用機構2005
- Author(s)
  伊藤英晃
- Journal Title
  
  哺乳類分子シャペロンの作用機構 77(9)
  
  Pages: 1137-1151
- NAID
  40006975121
- Data Source
  KAKENHI-PROJECT-16651056
[Journal Article] Unique molecular recognition property of bis-modified β-cyclodextrin dimmer in collaboration with γ-cyclodextrins.2005
- Author(s)
  Toda M, Ogawa N, Itoh H, Hamada F.
- Journal Title
  
  Analytica Chimia Acta. 548
  
  Pages: 1-10
- Data Source
  KAKENHI-PROJECT-16651056
[Journal Article] 73-kDa molecular chaperone HSP73 is a direct target of antibiotic gentamicin.2004
- Author(s)
  Miyazaki T, Sagawa R, Honma T, Noguchi S, Harada T, Komatsuda A, Ohtani H, Wakui H, Sawada KI, Otaka M, Watanabe S, Jikei M, Ogawa N, Hamada F, Itoh H.
- Journal Title
  
  J Biol Chem 279(17)
  
  Pages: 17295-17300
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571011
[Journal Article] S100A1 is a novel molecular chaperone and a member of the Hsp70/Hsp90 multichaperone complex.2004
- Author(s)
  Okada, M., Hatakeyama, T., Itoh, H., Tokuta, H., Kobayashi, R.
- Journal Title
  
  Journal of Biological Chemistry 279
  
  Pages: 4221-4233
- Data Source
  KAKENHI-PROJECT-16651056
[Journal Article] Methylprednisolone-induced expression of mitochondrial heat shock protein 60 protects mitochondrial membrane potential in the hypoxic rat liver.2004
- Author(s)
  Motoyama, S., Saito, S., Itoh, H., Minamiya, Y., Maruyama, K., Okuyama, M., Ogawa, J.
- Journal Title
  
  Shock 22
  
  Pages: 234-239
- Data Source
  KAKENHI-PROJECT-16651056
[Journal Article] Mammalian HSP60 is quickly sorted into the mitochondria under conditions of dehydration.2002
- Author(s)
  Itoh H, Komatsuda A, Ohtani H, Wakui H, et al.
- Journal Title
  
  Eur J Biochem 269(23)
  
  Pages: 5931-5938
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571011
[Journal Article] Characterization of the 105-kDa molecular chaperone. Identification, biochemical properties, and localization.2002
- Author(s)
  Matsumori M, Itoh H, Toyoshima I, Komatsuda A, et al.
- Journal Title
  
  Eur J Biochem 269(22)
  
  Pages: 5632-5641
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14571011
[Journal Article] Mammalian HSP60 is quickly sorted into the mitochondria under conditions of dehydration.2002
- Author(s)
  Itoh H, Komatsuda A, Ohtani H, Wakui H, Imai H, Sawada K, Otaka M, Ogura M, Suzuki A, Hamada F.
- Journal Title
  
  Eur J Biochem 269(23)
  
  Pages: 5931-5938
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571011
[Journal Article] Characterization of the 105-kDa molecular chaperone. Identification, biochemical properties, and localization.2002
- Author(s)
  Matsumori M, Itoh H, Toyoshima I, Komatsuda A, Sawada K, Fukuda J, Tanaka T, Okubo A, Kinouchi H, Mizoi K, Hama T, Suzuki A, Hamada F, Otaka M, Shoji Y, Takada G.
- Journal Title
  
  Eur J Biochem 269 (22)
  
  Pages: 5632-5641
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14571011
[Presentation] HSP90 と DNA polymerase ηの相互作用解析2013
- Author(s)
  羽賀愛沙美，岡本知也，畠山詩織，菅原卓，南条博，伊藤英晃
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-24659357
[Presentation] HSP90とDNA polymeraseηの相互作用解析2013
- Author(s)
  羽賀愛沙美,岡本知也,畠山詩織,菅原卓,南條博,伊藤英晃
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-24659357
[Presentation] DNA polymerase ηと HSP90 の相互作用解析2013
- Author(s)
  羽賀愛沙美、岡本知也、畠山詩織、黒澤友翼、三瓶杏、西聡美、菅原卓、南條博、伊藤英晃
- Organizer
  臨床ストレス応答学会
- Place of Presentation
  信州大学
- Data Source
  KAKENHI-PROJECT-24659357
[Presentation] DNA polymeraseηとHSP90の相互作用解析2013
- Author(s)
  羽賀愛沙美,岡本知也,畠山詩織,黒澤友翼,三瓶杏,西聡美,菅原卓,南條博,伊藤英晃
- Organizer
  第8回臨床ストレス応答学会大会
- Place of Presentation
  信州大学
- Year and Date
  2013-11-15
- Data Source
  KAKENHI-PROJECT-24659357

1. WAKUI Hideki (70240463)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
2. KOMATSUDA Atsushi (70272044)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
3. OTAKA Michiro (30250872)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. KINOUCHI Hiroyuki (30241623)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. JIKEI Mitsutoshi (70251618)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. WATANABE Sumio (20138225)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KOBAYASHI Ryoji (00020917)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 大谷浩 (20333932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

ITOH Hideaki 伊藤 英晃

Research Projects

Research Products

Co-Researchers

Analysis of the cell neoplastic transformation mechanism based on the molecular chaperone HSP90Principal Investigator

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プロティンチップを用いた疾患特異マーカー検出システムの構築Principal Investigator

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蛋白質のフオールディング異常と神経細胞変性の解析Principal Investigator

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Review Section

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An analysis of mitochondrial transport mechanisms and physiological functions of mammalian molecular chaperone HSP60Principal Investigator

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哺乳動物における分子シャペロンの活性発現機構Principal Investigator

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哺乳類HSPのシャペロン活性発現機構の解析Principal Investigator

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ITOH Hideaki 伊藤英晃