SAYAMA Koji 佐山浩二

Researcher Number	80187286
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2021: 愛媛大学, 医学系研究科, 教授 2012 – 2015: 愛媛大学, 医学(系)研究科(研究院), 教授 2011 – 2012: 愛媛大学, 大学院・医学系研究科, 教授 2007 – 2010: Ehime University, 大学院・医学系研究科, 准教授 2001 – 2005: 愛媛大学, 医学部, 助教授 1997 – 2000: 愛媛大学, 医学部・附属病院, 講師 1998: EHIME UNIVERSITY,UNIVERSITYHOSPITAL,ASSISTANT PROFESSOR, 医学部附属病院, 講師
Review Section/Research Field	Principal Investigator Dermatology / Dermatology / Basic Section 53050:Dermatology-related Except Principal Investigator Dermatology / Dermatology
Keywords	Principal Investigator 角化細胞 / MAP kinase / 自然免疫 / ASK1 / 分化 / keratinocyte / 皮膚 / アポトーシス / cre recombinase / knockout mouse … More / epiregulin / amphiregulin / TGF-alpha / HB-EGF / siRNA / PI3 kinase / apoptosis / differentiation / p38MAP kinase / JNK / 表皮 / loxP / Cre / ケラチノサイト / epidermis / インフラマソーム / 細菌感染 / cre-recombinase / TAK1 / NF-кB / ノックアウトマウス / NF-kB / 細胞内シグナル / 皮膚感染症 / 抗炎症作用 / 非平衡大気圧プラズマ / 乾癬 / プラズマ / TGF-α / knokuout mouse / bacteria / wound healing / skin / トランスジェニック / 創傷治癒 / P38 MAP kinase / keratinocytes / p38 / p38 MAP kinase / Adherens junction / Desmosome / Cadherin / Desmocollin-3 / Desmoglein-3 / Adenovirus Vector / Keratinocytes / クラチノカイト / アデノウイルスヘクター / アデノウィルスベクター / アドヘレンスジャンクション / デスモゾーム / カドヘリン / デスモコリン3 / デスモグレイン3 / アデノウイルスベクター / アレルギー / 表皮角化細胞 / KOマウス / smad / Smad / TGF-beta / Innate immunity / バリア障害 / エクリン汗 / IL-31 / IL-1 / バリア異常 / 汗 / アトピー性皮膚炎 / 表皮分化 / 細菌 / 尋常性乾癬 / TLR / 表皮ブドウ球菌 / 黄色ブドウ球菌 / Th17 / SPF / 無菌マウス / K5-Cre / LC / Atg5 / オートファジー / 角化細 / マウス / 臨床研究 / 再生 / マウスモデル / 毛周期 / βグルカン / 円形脱毛症 / ユビキチン / Ubc13 … More Except Principal Investigator adenovirus vector / Toll-like receptor / real time PCR / MMP / ADAM / HB-EGF / autocrine / keratinocytes / 表皮細胞 / STAT / CIS / SOCS / 表皮角化細胞 / Virus infection / Wound Healing / Anti-microbial peptide / Innate Immunity / Differentiation / Keratinocyte / Epidermis / 細胞内シグナル / MIP3α / 細菌 / MAP kinase / toll-like receptor / ASK1 / 皮膚 / 創傷治療 / ウイルス感染 / 創傷治癒 / 抗菌ペプチド / 自然免疫 / 分化 / 角化細胞 / 表皮 / conditional knockout mouse / adnovirus vector / Adenovinis vector / 皮膚特異的ノックアウトマウス / interleukin / interferon / 尋常性乾癬 / サイトカイン / インターフェロン / インターロイキン Less

非平衡大気圧プラズマ（冷たいプラズマ）による皮膚免疫抑制作用の解明Principal Investigator
- Principal Investigator
  
  佐山浩二
- Project Period (FY)
  2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Ehime University
Regulation of epidermal innate immunity by Smurf/ArkadiaPrincipal Investigator
- Principal Investigator
  
  Koji Sayama
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Ehime University
Analyses of eccrine sweat reveal pathogenesis of atopic dermatitisPrincipal Investigator
- Principal Investigator
  
  SAYAMA Koi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Ehime University
Role of Atg5-dependent autophagy in innate immunity of epidermal keratinocytesPrincipal Investigator
- Principal Investigator
  
  SAYAMA Koji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Ehime University
Involvement of microflora-induced Th17 cells in psoriasisPrincipal Investigator
- Principal Investigator
  
  SAYAMA Koji
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Ehime University
超微粒子化βグルカンによるNF-κB活性化を応用した円形脱毛症の新規治療法の開発Principal Investigator
- Principal Investigator
  
  佐山浩二
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Ehime University
Regulation of keratinocyte differentiation and innate immunity by innate immune regulator Ubc13Principal Investigator
- Principal Investigator
  
  SAYAMA Koji
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Ehime University
Regulation of skin innate immunity by epidermal differentiation
- Principal Investigator
  
  HASHIMOTO Koji
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Dermatology
- Research Institution
  Ehime University
Analysis of the specific function of EGF family in epidermal keratinocytes using siRNA transgenic mousePrincipal Investigator
- Principal Investigator
  
  SAYAMA Koji
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Ehime University
Analysis of SOCS/CSI family in skin
- Principal Investigator
  
  HASHIMOTO Koji
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Ehime University
Research on inhibitors for autocrine and cross-induction mechanism in human keratinocytes
- Principal Investigator
  
  HASHIMOTO Koji
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Ehime University
Role of keratinocyte apoptosis and differentiation regulated by ASK1 in wound healingPrincipal Investigator
- Principal Investigator
  
  SAYAMA Koji
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Ehime University
Keratinocyte apoptosis by Daxx-ASK1-JNK-p38 pathwayPrincipal Investigator
- Principal Investigator
  
  SAYAMA Koji
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Ehime University
Differential effects of dominant negative mutants of desmoglein, desmocollin, and E-cadherin on cell-cell adhesion of keratinocytes.Principal Investigator
- Principal Investigator
  
  SAYAMA Koji
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Ehime University

All 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

[Book] Saishinhifukagakutaikei 2006-2007, Innate immunity of keratinocytes (in Japanese).2006
- Author(s)
  Koji Sayama
- Publisher
  Nakayama Shoten
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209035
[Book] 最新皮膚科学体系2006-2007、表皮ケラチノサイトの自然免疫86-94p2006
- Author(s)
  佐山浩二
- Total Pages
  346
- Publisher
  中山書店
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209035
[Book] 皮膚免疫ハンドブック改訂2版、自然免疫120-129p2005
- Author(s)
  佐山浩二
- Total Pages
  390
- Publisher
  中外医学社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209035
[Book] Handbook for skin immunology, Vol2, Innate Immunity (in Japanese).2005
- Author(s)
  Koji Sayama
- Publisher
  Chugai Igakusha
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209035
[Journal Article] Cell motion predicts human epidermal stemness.2015
- Author(s)
  Nanba D, Toki F, Tate S, Imai M, Matsushita N, Shiraishi K, Sayama K, Toki H, Higashiyama S, Barrandon Y.
- Journal Title
  
  J Cell Biol.
  
  Volume: 209 Issue: 2 Pages: 305-315
- DOI
  10.1083/jcb.201409024
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390074, KAKENHI-PUBLICLY-25112712, KAKENHI-PROJECT-26461660, KAKENHI-PROJECT-26670143, KAKENHI-PROJECT-25293245
[Journal Article] Cefcapene pivoxil hydrochloride is a potentially new treatment for palmoplantar pustulosis with pustulotic arthro-osteitis2015
- Author(s)
  Murakami M, Masuda K, Utsunomiya R, Oda F, Namba C, and Sayama K.
- Journal Title
  
  Dermatology
  
  Volume: 231 Issue: 4 Pages: 304-311
- DOI
  10.1159/000439401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293245
[Journal Article] Vesicular LL-37 contributes to inflammation of the lesional skin of palmoplantar pustulosis.2014
- Author(s)
  Murakami M, Kaneko T, Nakatsuji T, Kameda K, Okazaki H, Dai X, Hanakawa Y, Tohyama M, Ishida-Yamamoto A, Sayama K.
- Journal Title
  
  PLoS One.
  
  Volume: 9 Issue: 10 Pages: 304-311
- DOI
  10.1371/journal.pone.0110677
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591620, KAKENHI-PROJECT-25293245, KAKENHI-PROJECT-25461670
[Journal Article] Pressure sore-like ulcers on acneiform papules caused by EGFR inhibitors2013
- Author(s)
  Miyawaki S, Tohyama M, Irifune K, Ito R, and Sayama K.
- Journal Title
  
  Int Wound J
  
  Volume: 21 Issue: 5 Pages: 1-2
- DOI
  10.1111/iwj.12070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293245
[Journal Article] The “rat bite” streptbacillosis caused the acute generalized pustular bacterid but not the palmoplantar pustulosis2013
- Author(s)
  Murakami M, Ishida-Yamamoto A, Morhenn VB, and Sayama K.
- Journal Title
  
  The Lancet Infect Dis
  
  Volume: 13 Issue: 8 Pages: 655-656
- DOI
  10.1016/s1473-3099(13)70103-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293245
[Journal Article] Eccrine sweat contains IL-1α, IL-1β and IL-31 and activates epidermal keratinocytes as a danger signal.2013
- Author(s)
  Dai X, Okazaki H, Hanakawa Y, Murakami M, Tohyama M, Shirakata Y, Sayama K.
- Journal Title
  
  PLoS One.
  
  Volume: ８ Issue: 7 Pages: 1-8
- DOI
  10.1371/journal.pone.0067666
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591628, KAKENHI-PROJECT-24591655, KAKENHI-PROJECT-24659532, KAKENHI-PROJECT-24791160, KAKENHI-PROJECT-25293245
[Journal Article] Eccrine sweat contains IL-1α, IL-1βand IL-31 and activates epidermal keratinocytes as a danger signal2013
- Author(s)
  Dai X, Okazaki H, Hana awa Y, Murakami M, Tohyama M, Shirakata Y, Sayama K
- Journal Title
  
  PLoS One
  
  Volume: 8(7)
- Data Source
  KAKENHI-PROJECT-24659532
[Journal Article] INF-alpha Enhances IL-22 Receptor Expression in Keratinocytes:A Possible Role in the Development of Psoriasis.2012
- Author(s)
  Tohyama M, Yang L, Hanakawa Y, Dai X, Shirakata Y, and Sayama K.
- Journal Title
  
  J Invest Dermatol;
  
  Volume: 132 Issue: 5 Pages: 1933-1935
- DOI
  10.1007/s00109-009-0457-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390218, KAKENHI-PROJECT-24659532
[Journal Article] Nuclear translocation of phosphorylated STAT3 regulates VEGF-A-induced lymphatic endothelial cell migration and tube formation2011
- Author(s)
  Okazaki H, Tokumaru S, Hanakawa Y, Shiraishi K, Shirakata Y, Dai X, Yang L, Tohyama M, Hashimoto K, and Sayama K.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 412 Pages: 441-445
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659207
[Journal Article] Mite allergen is a danger signal for the skin via activation of inflamasome in keratinocytes2011
- Author(s)
  Dai X, Sayama K, Tohyama M, Shirakata Y, Hanakawa Y, Tokumaru S, Yang L, Hirakawa S, and Hashimoto K.
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: 127 Issue: 3 Pages: 806-814
- DOI
  10.1016/j.jaci.2010.12.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390218
[Journal Article] Mite allergen is a danger signal for the skin via activation of the inflammasome in keratinocytes2011
- Author(s)
  Dai X, Sayama K, Tohyama M, Shirakata Y, Hanakawa Y, Tokumaru S, Yang L, Hirakawa S, and Hashimoto K.
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: 127 Pages: 806-814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659207
[Journal Article] Nuclear translocation of phosphorylated STAT3 regulates VEGF-A-induced lymphatic endothelial cell migration and tube formation2011
- Author(s)
  Okazaki H, et al
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 412 Issue: 3 Pages: 441-5
- DOI
  10.1016/j.bbrc.2011.07.111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591434, KAKENHI-PROJECT-22390218
[Journal Article] E2 polyubiquitin-conjugating enzyme Ubc13 in keratinocytes is essential for epidermal integrity.2010
- Author(s)
  Sayama K
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 30042-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390218
[Journal Article] Inflammatory mediator TAK1 regulates hair follicle morphogenesis and anagen induction shown by using keratinocyte-specific TAK1-deficient mice.2010
- Author(s)
  Sayama K
- Journal Title
  
  PLoS One
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659207
[Journal Article] PPARγmediates innate immunity by regulating the 1α, 25-dihydroxyvitamin D3 induced hBD-3 and cathelicidin in human keratinocytes2010
- Author(s)
  Dai X, Sayama K, Tohyama M, Shirakata Y, Hanakawa Y, Tokumaru S, Yang L, Hirakawa S, and Hashimoto K.
- Journal Title
  
  J Dermatol Sci
  
  Volume: 60 Issue: 3 Pages: 179-186
- DOI
  10.1016/j.jdermsci.2010.09.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390218
[Journal Article] Inflammatory mediator TAK1 regulates hair follicle morphogenesis and anagen induction shown by using keratinocyte-specific TAK1-dificient mice.2010
- Author(s)
  Sayama K, Kajiya K, Sugawara K, Sato S, Hirakawa S, Shirakata Y, Hanakawa Y, Dai X, Ishimatsu-Tsuji Y, Metzger D, Chambon P, Akira S, Paus R, Kishimoto J, and Hashimoto K.
- Journal Title
  
  PLoS One
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659207
[Journal Article] E2 Polyubiquitin-conjugating enzyme Ubc13 in keratinocytes is essential for epidermal integrity2010
- Author(s)
  Sayama K, Yamamoto M, Shirakata Y, Hanakawa Y, Hirakawa S, Dai X, Tohyama M, Tokumaru S, Shin MS, Sakurai H, Akira S, and Hashimoto K.
- Journal Title
  
  J Biol Chem;
  
  Volume: 285 Issue: 39 Pages: 30042-30049
- DOI
  10.1074/jbc.m110.106484
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390218
[Journal Article] Inflammatory mediator TAK1 regulates hair follicle morphogenesis and anagen induction shwn by using deratinocyte-specific TAK1-dificient mice2010
- Author(s)
  Sayama K, Kajiya K, Sugawara K, Sato S, Hirakawa S, Shirakata Y, Hanakawa Y, Dai X, Ishimatsu-Tsuji Y, Metzger D, Chambon P, Akira S, Paus R, Kishimoto J, and Hashimoto K.
- Journal Title
  
  PloS One
  
  Volume: 5 Issue: 6 Pages: e11275-e11275
- DOI
  10.1371/journal.pone.0011275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390218
[Journal Article] PPARγmediates innate immunity by regulating the 1α, 25-dihydroxyvitamin D3 induced hBD-3 and cathelicidin in human keratinocytes2010
- Author(s)
  Dai X, Sayama K, Tohyama M, Shirakata Y, Hanakawa Y, Tokumaru S, Yang L, Hirakawa S, and Hashimoto K.
- Journal Title
  
  J Dermatol Sci
  
  Volume: 60 Pages: 179-186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659207
[Journal Article] E2 polyubiquitin-conjugating enzyme Ubc 13 in keratinocytes is essential for epidermal integrity2010
- Author(s)
  Sayama K, Yamamoto M, Shirakata Y, Hanakawa Y, Hirakawa S, Dai X, Tohyama M, Tokumaru S, Shin MS, Sakurai H, Akira S, and Hashimoto K.
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 30042-30049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659207
[Journal Article] E2 polyubiquitin-conjugating enzyme Ubc13 in keratinocytes is essential for epidermal integrity.2010
- Author(s)
  Sayama K
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Pages: 30042-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659207
[Journal Article] Inflammatory mediator TAK1 regulates hair follicle morphogenesis and anagen induction shown by using keratinocyte-specific TAK1-deficient mice.2010
- Author(s)
  Sayama K
- Journal Title
  
  PLoS One
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390218
[Journal Article] Nodal lymphangiogenesis and metastasis: Role of tumor-induced lymphatic vessel activation in extramammary Paget's disease Am J Pathol2009
- Author(s)
  Hirakawa S, Detmar M, Kerjaschki D, Nagamatsu S, Matsuo K, Tanemura A, Kamata N, Higashikawa K, Okazaki H, Kameda K, Nishida-Fukuda H, Mori H, Hanakawa Y, Sayama K, Shirakata Y, Tohyama M, Tokumaru S, Katayama I, Hashimoto K.
- Journal Title
  
  175
  
  Pages: 2235-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390297
[Journal Article] Malignant acanthosis nigricans with enhanced expression of fibroblast growth factor receptor 3 Acta Derm Venereol2009
- Author(s)
  Hida Y, Kubo Y, Nishio Y, Murakami S, Fukumoto D, Sayama K, Hashimoto K, Arase S
- Journal Title
  
  89
  
  Pages: 435-437
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390297
[Journal Article] Living skin equivalents constructed using human amnions as a matrix J Dermatol Sci2009
- Author(s)
  Yang L, Shirakata Y, Tokumaru S, Xiuju D, Tohyama M, Hanakawa Y, Hirakawa S, Sayama K Hashimoto K.
- Journal Title
  
  56
  
  Pages: 188-195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390297
[Journal Article] IL-17 and IL-22 mediate IL-20 subfamily cytokine production in cultured keratinocytes via increased IL-22 receptor expression Eur J Immunol2009
- Author(s)
  Tohyama M, Hanakawa Y, Shirakata Y, Dai X, Yang L, Hirakawa S, Tokumaru S, Okazaki H, Sayama K, Hashimoto K.
- Journal Title
  
  39
  
  Pages: 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390297
[Journal Article] The influence of hepatic damage on serum soluble Fas ligand levels of patients with drug rashes2009
- Author(s)
  Tohyama M, Shirakata Y, Sayama K, Hashimoto K.
- Journal Title
  
  Allergy Clin Immunol 123
  
  Pages: 971-972
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390297
[Journal Article] Increased resistance to cationic antimicrobial peptide LL-37 in methicillin-resistant strains of staphylococcus aureus J Antimicrob Chemother2008
- Author(s)
  Ouhara K, Komatsuzawa H, Kawai T, Nishi H, Fujiwara T, Fujiue Y, Kuwabara M, Sayama K, Hashimoto K, Sugai M.
- Journal Title
  
  61
  
  Pages: 1266-1269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390297
[Journal Article] The NF-kappaB, P38 MAPK and STAT1 pathways differentially regulate the dsRNA-mediated innate immune responses of epidermal keratinocytes.2008
- Author(s)
  Dai X, Sayama K, Tohyama M, Shirakata Y, Yang L, Hirakawa S, Tokumaru S, Hashimoto K.
- Journal Title
  
  Int Immunology 20
  
  Pages: 901-909
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390297
[Journal Article] PPARgamma is an important transcription factor in 1 alpha2008
- Author(s)
  Dai X, Sayama K, Shirakata Y, Tokumaru S, Yang L, Tohyama M, Hirakawa S, Hanakawa Y, Hashimoto K.
- Journal Title
  
  25-dihydroxyvitamin D3-induced involucrin expression. J Dermatol Sci 50
  
  Pages: 53-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390297
[Journal Article] PPARgamma is an important transcription factor in 1alpha, 25-dihydroxyvitamin D3-induced involucrin expression2008
- Author(s)
  Dai, X. Sayama, K. Shirakata, Y. Tokumaru, S. YangL. Tohyama, M. Hirakawa, S. Hanakawa, Y., Hashimoto, K.
- Journal Title
  
  J Dermatol Sci 50
  
  Pages: 53-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390297
[Journal Article] A marked increase in serum soluble Fas ligand in drug-induced hypersensitivity syndrome.2008
- Author(s)
  Tohyama M, Shirakata Y, Sayama K, Hashimoto K.
- Journal Title
  
  Br J Dermatol 159
  
  Pages: 981-984
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390297
[Journal Article] The NF-kappaB, P38MAPK and STAT1 pathways differentially regulate the dsRNA-mediated innate immune responses of epidemal keratinocytes.2008
- Author(s)
  Dai, X. Sayama, K. Tohyama. M. Shirakata, Y. Yang, L. Hirakawa, S, Todumaru, S., Hashimoto, K.
- Journal Title
  
  Int Immunology 20
  
  Pages: 901-909
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390297
[Journal Article] STAT5a/PPAR gamma pathway regulates involucrin expression in keratinocyte differentiation J Invest Dermato2007
- Author(s)
  Dai, X. Sayama, K. Shirakata, Y. Hanakawa, Y. Yamasaki, K. Tokumaru, S. Yang, L. Wang, X. Hirakawa, S. Tohyama, M. Yamauchi, T. Takashi, K. Kagechika, H., Hashimoto, K.
- Journal Title
  
  127
  
  Pages: 1728-1735
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390297
[Journal Article] STAT5a/PPARgamma pathway regulates involucrin expression in keratinocyte differentiation2007
- Author(s)
  Dai X, Sayama K, Shirakata Y, Hanakawa Y, Yamasaki K, Tokumaru S, Yang L, Wang X, Hirakawa S, Tohyama M, Yamauchi T, Takashi K, Kagechika H, Hashimoto K.
- Journal Title
  
  J Invest Dermatol 127
  
  Pages: 1728-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390297
[Journal Article] Suppressor of cytokine signaling 3 negative regulation of signal transducer and activator of transcription 3 in platelet-derived growth factor-induced fibroblast migration J Dermatol2007
- Author(s)
  Nagai, H. Tokumaru, S. Sayama, K. Shirakata, Y. Hanakawa, Y. Hirakawa, S. Dai, X. Tohyama, M. Yang, L. Hashimoto, K.
- Journal Title
  
  34
  
  Pages: 523-530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390297
[Journal Article] CXCL 16 is a novel mediator of the innate immunity of epidermal keratinocytes Int Immunol2007
- Author(s)
  Tohyma, M. Sayama, K. Komatsuzawa, H. Hanakawa, Y. Shirakata, Y. Dai, X. Yang, L. Tokumaru, S. Nagai, H. Hirakawa, S. Sugai, M., Hashimoto, K.
- Journal Title
  
  19
  
  Pages: 1095-1102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390297
[Journal Article] CXCL16 is a novel mediator of the innate immunity of epidermal keratinocytes2007
- Author(s)
  Tohyama M, Sayama K, Komatsuzawa H, Hanakawa Y, Shirakata Y, Dai X, Yang L, Tokumaru S, Nagai H, Hirakawa S, Sugai M, Hashimoto K
- Journal Title
  
  Int Immunol 19
  
  Pages: 1095-102
- NAID
  10020108093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390297
[Journal Article] Innate defences against methicillin-resistant Staphylococcus aureus (MRSA) infection.2006
- Author(s)
  Komatsuzawa H, Ouhara K, Yamada S, Fujiwara T, Sayama K, Hashimoto K, Sugai M
- Journal Title
  
  J Pathol. 208
  
  Pages: 249-260
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209035
[Journal Article] ASK1-mediated keratinocyte differentiation regulates the expression of β-defensins, LL37, and TLR22005
- Author(s)
  Sayama K
- Journal Title
  
  Eur J Immun 35
  
  Pages: 1886-1895
- Data Source
  KAKENHI-PROJECT-15209035
[Journal Article] Heparin-binding EGF-like growth factor accelerates keratinocyte migration and skin wound healing.2005
- Author(s)
  Shirakata Y, Kimura R, Nanba D, Iwamoto R, Tokumaru S, Morimoto C, Yokota K, Nakamura M, Sayama K, Mekada E, Higashiyama S, Hashimoto K
- Journal Title
  
  J Cell Sci 118
  
  Pages: 2363-2370
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209035
[Journal Article] SOCS3/CIS3 negative regulation of STAT3 in HGF-induced keratinocyte migration.2005
- Author(s)
  Tokumaru S, Sayama K, Yamasaki K, Shirakata Y, Hanakawa Y, Yahata Y, Dai X, Tohyama M, Yang L, Yoshimura A, Hashimoto K.
- Journal Title
  
  Biochem Biophys Res Commun. 327
  
  Pages: 100-105
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390343
[Journal Article] SOCS3/CIS3 negative regulation of STAT3 in HGF-induced keratinocyte migration.2005
- Author(s)
  Tokumaru S, Sayama K, Yamasaki K, et al.
- Journal Title
  
  Biochem Biophys Res Commun. 327
  
  Pages: 100-105
- Data Source
  KAKENHI-PROJECT-15209035
[Journal Article] Cre-loxP adenovirus-mediated foreign gene expression in skin-equivalent keratinocytes.2005
- Author(s)
  Hanakawa Y, Shirakata Y, Nagai H, Yahata Y, Tokumaru S, Yamasaki K, Tohyama M, Sayama K, Hashimoto K.
- Journal Title
  
  Br J Dermatol. 152
  
  Pages: 1391-1392
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209035
[Journal Article] New mechanisms of skin innate immunity : ASK1-mediated keratinocyte differentiation regulates the expression of β-defensins, LL37, and TLR2.2005
- Author(s)
  Sayama K, Komatsuzawa H, Yamasaki K, Shirakata Y, Hanakawa Y, Ouhara K, Tokumaru S, Dai X, Tohyama M, Ten Dijke P, Sugai M, Ichijo H, Hashimoto K
- Journal Title
  
  Eur J Immun 35
  
  Pages: 1886-1895
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209035
[Journal Article] Induction of keratinocyte migration via transactivation of the EGF receptor by the antimicrobial peptide LL-37.2005
- Author(s)
  Tokumaru S, Sayama K, Shirakata Y, Komatsuzawa H, Ouhara K, Hanakawa Y, Yahata Y, Dai X, Tohyama M, Nagai H, Yang L, Higashiyama S, Yoshimura A, Sugai M, Hashimoto K
- Journal Title
  
  J Immunol. 175
  
  Pages: 4662-4668
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209035
[Journal Article] ASK1-mediated keratinocyte differentiation regulates the expression of β-defensins,LL37,and TLR22005
- Author(s)
  SayamaK
- Journal Title
  
  EurJImmun 35
  
  Pages: 1886-1895
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15209035
[Journal Article] SOCS3/CIS3 negative regulation of STAT3 in HGF-induced keratinocyte migration.2005
- Author(s)
  Tokumaru S, Sayama K, Yamasaki K, Shirakata Y, et al.
- Journal Title
  
  Biochem Biophys Res Commun 327
  
  Pages: 100-105
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390343
[Journal Article] Susceptibilities of periodontopathogenic and cariogenic bacteria to antibacterial peptides, {beta}-defensins and LL37, produced by human epithelial cells.2005
- Author(s)
  Ouhara K, Komatsuzawa H, Yamada S, Shiba H, Fujiwara T, Ohara M, Sayama K, Hashimoto K, Kurihara H, Sugai M.
- Journal Title
  
  J Antimicrob Chemother. 55
  
  Pages: 888-896
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209035
[Journal Article] Microbubble-enhanced ultrasound for gene transfer into living skin equivalents.2005
- Author(s)
  Yang L, Shirakata Y, Tamai K, Dai X, Hanakawa Y, Tokumaru S, Yahata Y, Tohyama M, Shiraishi K, Nagai H, Wang X, Murakami S, Sayama K, Kaneda Y, Hashimoto K
- Journal Title
  
  J Dermatol Sci. 40
  
  Pages: 105-114
- NAID
  10018032379
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209035
[Journal Article] SOCS3/CIS3 negative regulation of STAT3 in HGF-induced keratinocyte migration.2005
- Author(s)
  Tokumaru S, Sayama K, Yamasaki K, Shirakata Y, Hanakawa Y, Yahata Y, Dai X, Tohyama M, Yang L, Yoshimura A, Hashimoto K.
- Journal Title
  
  Biochem Biophys Res Commun. 327
  
  Pages: 100-105
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209035
[Journal Article] TGF-beta is not involved in early phase growth inhibition of keratinocytes by lalpha,25(OH)2vitamin D3.2004
- Author(s)
  Shirakata Y, Ueno H, Hanakawa Y, Kameda K, Yamasaki K, Tokumaru S, Yahata Y, Tohyama M, Sayama K, Hashimoto K.
- Journal Title
  
  J Dermatol Sci. 36
  
  Pages: 41-50
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390343
[Journal Article] Keratinocyte G2/M growth arrest by 1,25-dihydroxyvitamin D3 is caused by Cdc2 phosphorylation through Wee1 and Myt1 regulation.2004
- Author(s)
  Dai X, Yamasaki K, Yang L, Sayama K, Shirakata Y, et al.
- Journal Title
  
  Journal of Investigative Dermatology 122
  
  Pages: 1356-1364
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390343
[Journal Article] Keratinocyte G2/M growth arrest by 1,25-dihydroxyvitamin D3 is caused by Cdc2 phosphorylation through Weel and Mytl regulation.2004
- Author(s)
  Dai X, Yamasaki K, Yang L, Sayama K, Shirakata Y, Tokumara S, Yahata Y, Tohyama M, Hashimoto K.
- Journal Title
  
  J Invest Dermatol. 122
  
  Pages: 1356-1364
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390343
[Journal Article] All-trans-retinoic acid induces interleukin-8 via the nuclear factor-kappaB and p38 mitogen-activated protein kinase pathways in normal human keratinocytes.2004
- Author(s)
  Dai X, Yamasaki K, Shirakata Y, Sayama K, Hashimoto K.
- Journal Title
  
  J Invest Dermatol. 123
  
  Pages: 1078-1085
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390343
[Journal Article] SOCS1 negative feedback of STAT1 activation is a key pathway in the dsRNA-induced innate immune response of human keratinocytes.
- Author(s)
  Dai X, Sayama K, Yamasaki K, Tohyama M, Shirakata Y, Hanakawa Y, Tokumaru S, Yahata Y, Yang L, Yoshimura A, Hashimoto K
- Journal Title
  
  J Invest Dermatol (in press). (in press). (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209035
[Journal Article] Cre-loxP adenovirus-mediated foreign gene expression in skin-equivalent keratinocytes.
- Author(s)
  Hanakawa Y, Shirakata Y, Nagai H, Yahata Y, Tokumaru S, Yamasaki K, Tohyama M, Sayama K, Hashimoto K.
- Journal Title
  
  Br J Dermatol. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390343
[Journal Article] Cre/loxP mediated gene transfer into living skin equivalent model
- Author(s)
  Hanakawa Y, Shirakata Y, Sayama K, et al.
- Journal Title
  
  Br.J Dermatol (In press)
- Data Source
  KAKENHI-PROJECT-15209035
[Journal Article] Bone morphogenetic protein-2 modulates Wnt and frizzled expression and enhances the canonical pathway of Wnt signaling in normal keratinocytes.
- Author(s)
  Yang L, Yamasaki K, Shirakata Y, Dai X, Tokumaru S, Yahata Y, Tohyama M, Hanakawa Y, Sayama K, Hashimoto K.
- Journal Title
  
  J Dermatol Sci (in press)
- NAID
  10020549817
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15209035
[Presentation] Smurfs E3 ubiquitin ligases negatively regulate TGF-beta signaling in keratinobytes2015
- Author(s)
  Shiraishi K, Dai X, Murakami M, Tohyama M, Matsushita N, Imamura T, and Sayama K.
- Organizer
  Society for Investigative Dermatolgy 2015 Annual meeting
- Place of Presentation
  Atlanta GA, USA
- Year and Date
  2015-05-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293245
[Presentation] Eccrine sweat simulates the release of IL-8 via IL-1 from epidermal keratinocytes as danger signal2013
- Author(s)
  Okazaki H, Dai X, Murakami M, Hanakawa Y, Tohyama M, Shirakata Y, and Sayama K
- Organizer
  International Investigative Dermatology
- Place of Presentation
  Edinburgh, UK
- Data Source
  KAKENHI-PROJECT-25293245
[Presentation] Eccrine sweat stimulates the release of IL-8 via IL-1 from epidermal keratinocytes as danger signal2013
- Author(s)
  Okazaki H, Dai H, Murakami M, Hanakawa Y, Tohyama M, Shirakata Y, Sayama K
- Organizer
  International Investigative Dermatology
- Place of Presentation
  Edinburgh, UK
- Data Source
  KAKENHI-PROJECT-24659532
[Presentation] CISH suppresses IL-17-induced CCL20 production from epidermal keratinocytes via inhibition of the Src/MEK/ERK pathway2013
- Author(s)
  Tohyama M, Shirakata Y, Hanakawa Y, Dai X, Okazaki H, Murakami M, Hashimoto K, and Sayama K.
- Organizer
  International Investigative Dermatology
- Place of Presentation
  Edinburgh, UK
- Data Source
  KAKENHI-PROJECT-25293245
[Presentation] Human cathelicidin (hCAP18/LL37) in pustules contributes to the pathogenesis of palmoplantar pustulosis2013
- Author(s)
  Murakami M, Okazaki H, Shirakata Y, Kaneko T, Ishida-Yamamoto A, Iizuka H, Morhenn VB, Gallo RL, and Sayama K
- Organizer
  International Investigative Dermatology
- Place of Presentation
  Edinburgh, UK
- Data Source
  KAKENHI-PROJECT-25293245
[Presentation] Eccrine sweat simulates the release of IL-8 via IL-1 from epidermal keratinocytes as danger signal2013
- Author(s)
  Okazaki H, Dai X, Murakami M, Hanakawa Y, Tohyama M, Shirakata Y, and Sayama K.
- Organizer
  International Investigative Dermatology
- Place of Presentation
  Edinburgh, UK
- Data Source
  KAKENHI-PROJECT-24659532
[Presentation] Intracellular dsRNA activates inflammasome in the keratinocytes resulting in the release of IL-182012
- Author(s)
  Dai X, Shirakata T, Tohyama M, Hanakawa Y, Okazaki H, and Sayama K.
- Organizer
  SID Annual Meeting & 75thAnniversary Celebration
- Place of Presentation
  North Carolina. USA
- Data Source
  KAKENHI-PROJECT-22390218
[Presentation] Autophagy is an innate immune system of epidermal keratinocytes.2012
- Author(s)
  Okazaki H, Dai X, Hanakawa Y, Shirakata Y, Tohyama M, and Sayama K.
- Organizer
  SID Annual Meeting
- Place of Presentation
  North Carolina, USA
- Data Source
  KAKENHI-PROJECT-22390218
[Presentation] Autophagy is induced by differentiation in epidermal keratinocytes.2012
- Author(s)
  1. Dai X, Okazaki H, Hanakawa Y, Shirakata Y, Murakami M, Tohyama M, and Sayama K.
- Organizer
  42nd Annual ESDR Meeting
- Place of Presentation
  Venice, Italy
- Data Source
  KAKENHI-PROJECT-24659532
[Presentation] Intracellular dsRNA activates inflammasome in the keratinocytes resulting in the release of IL-18.2012
- Author(s)
  Dai X, Shirakata T, Tohyama M, Hanakawa Y, Okazaki H, and Sayama K.
- Organizer
  SID Annual Meeting
- Place of Presentation
  North Carolina, USA
- Data Source
  KAKENHI-PROJECT-22390218
[Presentation] Autophagy is an innate immune system of epidermal keratinocytes.2012
- Author(s)
  Okazaki H, Dai X, Hanakawa Y, Shirakata Y, Tohyama M, and Sayama K
- Organizer
  SID Annual Meeting & 75thAnniversary Celebration
- Place of Presentation
  North Carolina. USA
- Data Source
  KAKENHI-PROJECT-22390218
[Presentation] Autophagy is induced by differentiation in epidermal keratinocytes.2012
- Author(s)
  Dai X, Okazaki H, Hanakawa Y, Shirakata Y, Murakami M, Tohyama M, and Sayama K.
- Organizer
  42ndAnnual ESDR Meeting
- Place of Presentation
  Venice, Italy
- Data Source
  KAKENHI-PROJECT-22390218
[Presentation] Autophagy is induced by differentiation in epidermal keratinocytes.2012
- Author(s)
  Dai X, Okazaki H, Hanakawa Y, Shirakata Y, Murakami M, Tohyama M, and Sayama K.
- Organizer
  42nd Annual ESDR Meeting
- Place of Presentation
  Venice, Italy
- Data Source
  KAKENHI-PROJECT-22390218
[Presentation] Mite allergen activates inflammasome in epidermal keratinocytes resulting in the production of IL-1beta and IL-182011
- Author(s)
  Dai X, Sayama K, Tohyama M, Shirakata Y, Hanakawa Y, Tokumaru S, Yang L, Hirakawa S, and Hashimoto K.
- Organizer
  22^<nd> World Congress of Dermatology
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-22659207
[Presentation] Nuclear translocation of Bcl3 and p50 by IL-22 produces HB-EGF, IL-8, S100A7, and human β-defensin 2 in keratinocytes of psoriasis.2011
- Author(s)
  Tohyama M, Hanakawa Y, Shirakata Y, Dai X, Otani T, Hashimoto K, and Sayama K
- Organizer
  The 41st Annual ESDR Meeting
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-22390218
[Presentation] Mite allergen activates inflammasome in epidermal keratinocytes resulting in the production of IL-1beta and IL-182011
- Author(s)
  Dai X, Sayama K, Tohyama M, Shirakata Y, Hanakawa Y, Tokumaru S, Yang L, Hirakawa S, and Hashimoto K
- Organizer
  22ndWorld Congress of Dermatology
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-22390218
[Presentation] Mite allergen is a danger signal for the skin2010
- Author(s)
  Sayama K, Dai X, Shirakata Y, Tohyama M, Miyawaki S, Hirakawa S, and Hashimoto K
- Organizer
  40thAnnual ESDR Meeting of the European Society for Dermatological Research
- Place of Presentation
  Helsinki, Finland
- Data Source
  KAKENHI-PROJECT-22390218
[Presentation] Mite allergen is a danger signal for the skin2010
- Author(s)
  Sayama K, Dai X, Shirakata Y, Tohyama M, Miyawaki S, Hirakawa S, and Hashimoto K.
- Organizer
  40^<th> Annual ESDR Meeting of the European Society for Dermatological Research
- Place of Presentation
  Helsinki, Finland
- Data Source
  KAKENHI-PROJECT-22659207
[Presentation] Mite allergen is a danger signal for the skin2010
- Author(s)
  Sayama K
- Organizer
  European Society for Investigative Dermatology
- Place of Presentation
  ヘルシンキ/フィンランド
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-22659207
[Presentation] Mite allergen is a danger signal for the skin2010
- Author(s)
  Sayama K
- Organizer
  European Society for Investigative Dermatology
- Place of Presentation
  ヘルシンキ/フィンランド
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-22390218
[Presentation] Inflammatory mediator TAK1 regulates hair follicle cycling2009
- Author(s)
  Sayama K, et al.
- Organizer
  The 69^<th> Annual Meeting of Society for Investigative Dermatology
- Place of Presentation
  Montreal, CANADA
- Data Source
  KAKENHI-PROJECT-19390297
[Presentation] Inflammatory mediator TAK1 regulates hair follicle cycling The 69th Annual Meeting of Society for Investigative Dermatology2009
- Author(s)
  Sayama K, Shirakata Y, Ishimatsu-Tsuji Y, Kajiya K, Hirakawa S, Sugawara K, Chambon P, Akira S, Paus R, Kishimoto J, Hashimoto K.
- Organizer
  Montreal, CANADA
- Data Source
  KAKENHI-PROJECT-19390297
[Presentation] Inflammatory mediator TAK1 regulates hair follicle cycling2009
- Author(s)
  Sayama K, et al.
- Organizer
  The 69^<th> Annual Meeting of Society for Investigative Dermatology
- Place of Presentation
  Montreal, CANADA
- Data Source
  KAKENHI-PROJECT-20659174
[Presentation] Conditional ablation of Ubc 13, a mediator of innate immunity, in keratinocytes induces abnomaldifferentiation, decreased proliferation, and apoptosis.2008
- Author(s)
  Sayama, K. Yamamoto, M. Hanakawa, Y. Shirakata, Y. Akira, S., Hashimoto, K.
- Organizer
  International Investigative Dermatology
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-19390297
[Presentation] The innate immunity mediator Ubc13-TAK1 is a master regulator of epidermal structure and apoptosis2008
- Author(s)
  Sayama, K.
- Organizer
  International Investigative Dermatology
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-19390297
[Presentation] Conditional ablation of Ubc 13, a mediator of innate immunity, in keratinocytes induces abnormal differentiation2008
- Author(s)
  Sayama, K. Yamamoto, M. Hanakawa, Y. Shirakata, Y. Akira, S., Hashimoto, K.
- Organizer
  decreased proliferation, and apoptosis. International Investigative Dermatology
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-19390297
[Presentation] Ablation of TAK1 in mouse keratinocytes disturbed hair follicle development2007
- Author(s)
  Sayama, K.Kajiya, K.Shirakata, Y.Hanakawa, Y.Hirakawa, S.Dai, X.Nagai, H.Akira, S.Kishimoto, J.and Hashimoto, K.
- Organizer
  68^h Annual Meeting of the Society for Investigative Dermatology
- Place of Presentation
  Los Angeles
- Data Source
  KAKENHI-PROJECT-19390297
[Presentation] TAK1 regulates hair follicle development in EDA receptor signaling 37th Annual European Society for Dermatological Research(ESDR)Meeting2007
- Author(s)
  Sayama, K. Kajiya, K. Shirakata, Y. Hanakawa, Y. Hirakawa, S. Akira, S. Kishimoto, J. Hashimoto, K.
- Organizer
  Zurich, Switzerland
- Data Source
  KAKENHI-PROJECT-19390297
[Presentation] Ablation of TAK1 in mouse keratinocytes disturbed hair follicle development 68th Annual Meeting of the Society for Investigative Dermatology2007
- Author(s)
  Sayama, K. Kajiya, K. Shirakata, Y. Hanakawa, Y. Hirakawa, S. Dai, X. Nagai, H. Akira, S. Kishimoto, J., Hashimoto, K.
- Organizer
  Los Angeles
- Data Source
  KAKENHI-PROJECT-19390297
[Presentation] Smurfs E3 ubiquitin ligases negatively regulate TGF-beta signaling in keratinocytes
- Author(s)
  Ken Shiraishi, Xiuju Dai, Masamoto Murkami, Mikiko Tohyama, Natsuki Matsushita, TAkeshi Imamura, Koji Sayama
- Organizer
  Society for Investigative Dermatology, 2015 Annual Meeting
- Place of Presentation
  Atlanta, GA, U.S.A.
- Year and Date
  2015-05-06 – 2015-05-09
- Data Source
  KAKENHI-PROJECT-25293245

1. SHIRAKATA Yuji (50226320)

# of Collaborated Projects: 7 results

# of Collaborated Products: 33 results
2. YAMASAKI Kenshi (40294798)

# of Collaborated Projects: 5 results

# of Collaborated Products: 13 results
3. HASHIMOTO Koji (00110784)

# of Collaborated Projects: 4 results

# of Collaborated Products: 15 results
4. HANAKAWA Yasushi (90284398)

# of Collaborated Projects: 2 results

# of Collaborated Products: 28 results
5. OKUMARU Sho (50398046)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. Shiraishi Ken (80710863)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. ICHIJO Hidenori (00242206)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. HIRAKAWA Satoshi (50419511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
9. Toyama Mikiko (60263935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. 村上信司 (50175626)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 村上正基 (20278302)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. YOSHINO Kouichirou

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 東山繁樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 松下夏樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 山本明美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAYAMA Koji 佐山 浩二

Research Projects

Research Products

Co-Researchers

非平衡大気圧プラズマ（冷たいプラズマ）による皮膚免疫抑制作用の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of epidermal innate immunity by Smurf/ArkadiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analyses of eccrine sweat reveal pathogenesis of atopic dermatitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of Atg5-dependent autophagy in innate immunity of epidermal keratinocytesPrincipal Investigator

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Involvement of microflora-induced Th17 cells in psoriasisPrincipal Investigator

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超微粒子化βグルカンによるNF-κB活性化を応用した円形脱毛症の新規治療法の開発Principal Investigator

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Regulation of keratinocyte differentiation and innate immunity by innate immune regulator Ubc13Principal Investigator

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Regulation of skin innate immunity by epidermal differentiation

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Analysis of the specific function of EGF family in epidermal keratinocytes using siRNA transgenic mousePrincipal Investigator

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Analysis of SOCS/CSI family in skin

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Research on inhibitors for autocrine and cross-induction mechanism in human keratinocytes

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Role of keratinocyte apoptosis and differentiation regulated by ASK1 in wound healingPrincipal Investigator

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Keratinocyte apoptosis by Daxx-ASK1-JNK-p38 pathwayPrincipal Investigator

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SAYAMA Koji 佐山浩二