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Aihara Makoto  相原 一

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AIHARA Makoto  相原 一

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Researcher Number 80222462
Other IDs
Affiliation (Current) 2025: 東京大学, 医学部附属病院, 教授
Affiliation (based on the past Project Information) *help 2015 – 2024: 東京大学, 医学部附属病院, 教授
2017: 東京大学, 医学部附属病院, 准教授
2014: 東京医科歯科大学, その他部局等, 教授
2014: 東京医科歯科大学, 医学部付属病院, 特任教授
2013: 北海道大学, その他の研究科, その他 … More
2011 – 2013: 東京大学, 医学部附属病院, 准教授
2010: 東京大学, 医学部附属病院, 講師
2008: 東京大学, 医学部・附属病院, 講師
2007: 東京大学, 大学院・医学系研究科, 講師
2006: 東京大学, 大学院医学系研究科, 講師
2004 – 2006: 東京大学, 医学部附属病院, 講師
2000: School of Medicine, Department of Ophthalmology, University of Tokyo, Assistant, 医学部・附属病院, 助手
2000: 東京大学, 医学部附属病院, 助手
1999: 東京大学, 医学部・付属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Basic Section 56060:Ophthalmology-related / Ophthalmology / Ophthalmology
Except Principal Investigator
Ophthalmology / Basic Section 56060:Ophthalmology-related / Basic Section 49010:Pathological biochemistry-related / Biomolecular chemistry / Health science and related fields / Anesthesiology / Ophthalmology
Keywords
Principal Investigator
緑内障 / 眼圧 / 圧センサー / 房水流出路 / ドラッグデリバリー / 瘢痕化 / 生体医用材料 / 機械受容体 / バイオマーカー / 脂質メディエーター … More / 細胞応答 / 生理活性脂質 / 房水 / 線維柱帯 / 圧受容体 / 細胞質型ホスポリパーゼAL / 遺伝子組み換え動物 / ロイ*トリユン / 遺伝子組換え動物 / 細胞質型ホスホリパーゼA2 / 眼病理 / 血小板活性化因子 / ロイコトリエン / プロスタグランディン / アラキドン酸 / 神経保護 / フラボノイド / 神経細胞死 / サル / フェレット / 外側膝状体 / 網膜神経節細胞 … More
Except Principal Investigator
緑内障 / 眼圧 / 生理活性脂質 / 脳・神経 / サイトカイン / 前房水 / 線維柱帯 / プロスタグランジンD2 / cDNA cloning / in situ hybridization / 遺伝子改変マウス / glaucoma / 網膜神経節細胞 / 実験的自己免疫性ぶどう膜炎 / プロスタグランジンD2 / 脈絡膜新生血管 / 拮抗薬 / 新生血管 / 加齢黄斑変性 / ぶどう膜炎 / Prostaglandin D2 / 房水 / AIM / 食細胞機構 / アイフレイル / 蛋白質 / G蛋白質共役型受容体 / シクロオキシゲナーゼ / 遺伝子欠損マウス / プロスタグランジン / 酵素 / G蛋白質結合型受容体 / 結晶構造解析 / 脂質メディエーター / 受容体拮抗薬 / 酵素阻害剤 / 外傷性脳障害 / 結晶構造 / 阻害薬 / 睡眠物質 / 危険性薬物 / 癌 / サプリメント / 血管新生 / 筋ジストロフィー / 肥満 / 炎症 / 睡眠 / 抗酸化食品 / Vavマウス / 緑内障モデル動物 / フラボノイド / 予防食品 / 緑内障モデルマウス / Vav / 抗酸化作用食品 / 眼圧変動 / Vav2遺伝子欠損マウス / 食品 / 生理学 / ストレス / 外科 / 能血液量 / 低侵襲検査 / 脳血液量 / 視野異常 / ロボット手術 / 周術期管理学 / 眼発生・再生医学 / 病的近視 / 再生医学 / 眼発生 / steroid / bovine trabecular meshwork culture cells / phenotype / myocilin / gene mutations / ステロイド / 牛隅角線維柱帯培養細胞 / フェノタイプ / ミオシリン / 遺伝子変異 / 高眼圧遺伝子改変マウス / Vav遺伝子欠損マウス / 高眼圧モデルマウス / 高眼圧モデル動物 / ESR1ノックアウトマウス / ESR1 / POAG / 原発開放隅角緑内障 / ESR2ノックアウトマウス / ESR2 / エストロゲン受容体 / 放射線 / GSK3β / γH2AX / 低酸素 / neuroprotection / latanoprost / H4K20me / ATM / DNA damage response / RGC / アポトーシス / 視神経保護 / ラタノプロスト / ヒストンH4K20メチル化 / 53BP1 / γ-H2AX / DNA損傷応答 / 遺伝子改変動物 / 神経科学 / 脳神経疾患 / シグナル伝達 / 遺伝子 / 疾患モデル動物 / RGC障害評価動物モデル / 眼細胞生物学 / 高次細胞障害 / 高次機能障害 / 神経再生 / 神経保護 Less
  • Research Projects

    (19 results)
  • Research Products

    (166 results)
  • Co-Researchers

    (41 People)
  •  組織瘢痕抑制と生体医用材料の融合による持続可能な革新的眼圧上昇抑制緑内障治療Principal Investigator

    • Principal Investigator
      相原 一
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      The University of Tokyo
  •  The role of ATX-TGFbeta balance on the pathology of IOP elevation in glaucoma subtypes.

    • Principal Investigator
      本庄 恵
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      The University of Tokyo
  •  Involvement of prostaglandin D2 in inflammatory chorioretinal disease

    • Principal Investigator
      Kaburaki Toshikatsu
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Jichi Medical University
  •  Regulation of visual deterioration and ocular diseases using phagocytic mechanisms

    • Principal Investigator
      Arai Satoko
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      The University of Tokyo
  •  ocular tissue response by intraocular pressure and aqueous humor in glaucoma - investigation for the mechanism and biomarkers of intraocular pressure regulationPrincipal Investigator

    • Principal Investigator
      Aihara Makoto
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      The University of Tokyo
  •  The role of ATX-LPA pathway on the pathology of IOP elevation in glaucoma

    • Principal Investigator
      HONJO MEGUMI
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      The University of Tokyo
  •  Examination of glaucoma preventive effect of antioxidant functional food using Vav gene deficient mouse

    • Principal Investigator
      Inoue Kaoru
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Health science and related fields
    • Research Institution
      Hokkaido University
  •  A Study to Search Factors which cause Transitional Visual Field Defects after Surgery under Steep Trendelenburg Position

    • Principal Investigator
      Shinokawa Miki
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Anesthesiology
    • Research Institution
      The University of Tokyo
  •  Interaction between brain function and inflammation mediated by prostaglandin D2

    • Principal Investigator
      Urade Yoshihiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biomolecular chemistry
    • Research Institution
      The University of Tokyo
      University of Tsukuba
  •  Regenerating lamina cribrosa as a novel treatment for glaucoma

    • Principal Investigator
      OHNO-MATSUI Kyoko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Ophthalmology
    • Research Institution
      Tokyo Medical and Dental University
  •  Investigation of the mechanisms of intraocular pressure regulation (elevation) by estrogen-receptor

    • Principal Investigator
      MABUCHI Fumihiko
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      University of Yamanashi
  •  Identification of the target molecule to control the intraocular pressure: A study of Vav deficient mice with ocular hypertension

    • Principal Investigator
      INOUE Kaoru
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Ophthalmology
    • Research Institution
      Hokkaido University
  •  Characterization of CFP-expressed Vav-deficient mice with spontaneous IOP elevation to evaluate pressure-dependent RGC death

    • Principal Investigator
      FUJIKAWA Keiko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Hokkaido University
  •  DNA damage response in development of glaucoma

    • Principal Investigator
      KATSURA Mari
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      The University of Tokyo
  •  緑内障性神経障害:網膜から高次脳神経及びグリア細胞に及ぶ系統的器質障害機構の解明Principal Investigator

    • Principal Investigator
      相原 一
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      The University of Tokyo
  •  Damage of retinal ganglion cells : Mechanism of the cell death in the local and central nervous system and protection and regeneration of the neural cells.

    • Principal Investigator
      ARAIE Makoto
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Ophthalmology
    • Research Institution
      The University of Tokyo
  •  24時間眼圧測定装置の開発Principal Investigator

    • Principal Investigator
      相原 一
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Ophthalmology
    • Research Institution
      The University of Tokyo
  •  Molecular genetics and cell biology of a glaucoma gene and the gene product

    • Principal Investigator
      SUZUKI Yasuyuki
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      University of Tokyo
  •  眼疾患モデルとしての変異マウス・アラキドン酸と血小板活性化因子の阻害Principal Investigator

    • Principal Investigator
      相原 一, 森 樹郎
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2000 Other

All Journal Article Presentation

  • [Journal Article] An Autotaxin-Induced Ocular Hypertension Mouse Model Reflecting Physiological Aqueous Biomarker2024

    • Author(s)
      Shimizu Shota、Honjo Megumi、Liu Mengxuan、Aihara Makoto
    • Journal Title

      Investigative Opthalmology Visual Science

      Volume: 65 Issue: 2 Pages: 32-32

    • DOI

      10.1167/iovs.65.2.32

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09807, KAKENHI-PROJECT-23K27749
  • [Journal Article] Effect of a fixed combination of ripasudil and brimonidine on aqueous humor dynamics in mice2024

    • Author(s)
      Yamagishi-Kimura Reiko、Honjo Megumi、Aihara Makoto
    • Journal Title

      Scientific Reports

      Volume: 14 Issue: 1

    • DOI

      10.1038/s41598-024-58212-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Journal Article] A MEK inhibitor arrests the cell cycle of human conjunctival fibroblasts and improves the outcome of glaucoma filtration surgery2024

    • Author(s)
      Lee Jinhee、Honjo Megumi、Aihara Makoto
    • Journal Title

      Scientific Reports

      Volume: 14 Issue: 1

    • DOI

      10.1038/s41598-024-52359-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09807, KAKENHI-PROJECT-23K27749
  • [Journal Article] Real-Time Measurement of Antiglaucoma Drugs in Porcine Eyes Using Boron-Doped Diamond Microelectrodes2024

    • Author(s)
      Ogata Genki、Yoneda Mao、Ogawa Risa、Hanawa Ai、Asai Kai、Yamagishi Reiko、Honjo Megumi、Aihara Makoto、Einaga Yasuaki
    • Journal Title

      ACS Sensors

      Volume: 9 Issue: 2 Pages: 781-788

    • DOI

      10.1021/acssensors.3c02088

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K09807, KAKENHI-PROJECT-21H03805
  • [Journal Article] Apoptosis inhibitor of macrophages/CD5L enhances phagocytosis in the trabecular meshwork cells and regulates ocular hypertension2023

    • Author(s)
      Nemoto Hotaka、Honjo Megumi、Arai Satoko、Miyazaki Toru、Aihara Makoto
    • Journal Title

      Journal of Cellular Physiology

      Volume: 238 Issue: 10 Pages: 2451-2467

    • DOI

      10.1002/jcp.31097

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09807, KAKENHI-ORGANIZER-21H05120, KAKENHI-PROJECT-23K27749
  • [Journal Article] The effect of axial length on the short-term outcomes of cataract surgery combined with ab interno trabeculotomy2023

    • Author(s)
      Goto Hiroki、Honjo Megumi、Omoto Takashi、Aihara Makoto
    • Journal Title

      Graefe's Archive for Clinical and Experimental Ophthalmology

      Volume: - Issue: 5 Pages: 1599-1606

    • DOI

      10.1007/s00417-023-06337-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Journal Article] Attenuation of laser-induced choroidal neovascularization by blockade of prostaglandin D2 receptor 2.2023

    • Author(s)
      Soga H, Inoue T, Urade Y, Ueta T, Kawashima H, Kaburaki T, Aihara M.
    • Journal Title

      Transl. Vis. Sci. Technol.

      Volume: 12 Issue: 5 Pages: 5-5

    • DOI

      10.1167/tvst.12.5.5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09681
  • [Journal Article] Effects of Brimonidine, Omidenepag Isopropyl, and Ripasudil Ophthalmic Solutions to Protect against H2O2-Induced Oxidative Stress in Human Trabecular Meshwork Cells2023

    • Author(s)
      Liu Mengxuan、Honjo Megumi、Yamagishi Reiko、Aihara Makoto
    • Journal Title

      Current Eye Research

      Volume: 48 Issue: 11 Pages: 1014-1025

    • DOI

      10.1080/02713683.2023.2235892

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K09807, KAKENHI-PROJECT-23K27749
  • [Journal Article] Synergic effects of EP2 and FP receptors co-activation on Blood-Retinal Barrier and Microglia2023

    • Author(s)
      Nakamura Natsuko、Honjo Megumi、Yamagishi Reiko、Sakata Rei、Watanabe Sumiko、Aihara Makoto
    • Journal Title

      Experimental Eye Research

      Volume: 237 Pages: 109691-109691

    • DOI

      10.1016/j.exer.2023.109691

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Journal Article] Contributing factors for intraocular pressure control in patients with mostly normal-tension glaucoma after initial Ex-PRESS drainage device implantation2023

    • Author(s)
      Aoyama Yurika、Sakata Rei、Fujishiro Takashi、Honjo Megumi、Shirato Shiroaki、Aihara Makoto
    • Journal Title

      Graefe's Archive for Clinical and Experimental Ophthalmology

      Volume: 262 Issue: 1 Pages: 191-201

    • DOI

      10.1007/s00417-023-06209-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Journal Article] Prostaglandin-Associated Periorbitopathy Symptom Alleviation After Switching Prostaglandin F Receptor Agonist to EP2 Receptor Agonist in Patients with Glaucoma2023

    • Author(s)
      Sakata Rei、Fujishiro Takashi、Saito Hitomi、Nakamura Natsuko、Honjo Megumi、Shirato Shiroaki、Miyamoto Etsuyo、Yamada Yoshiaki、Aihara Makoto
    • Journal Title

      Journal of Ocular Pharmacology and Therapeutics

      Volume: 39 Issue: 1 Pages: 63-69

    • DOI

      10.1089/jop.2022.0096

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Journal Article] A novel instrument to determine hue discrimination.2023

    • Author(s)
      Sawa M, Mizuochi M, Matsumura K, Aihara M, Yamagami S, Yamashita H, Kaburaki T.
    • Journal Title

      Jpn J Ophthalmol.

      Volume: 67 Issue: 3 Pages: 353-360

    • DOI

      10.1007/s10384-023-00983-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K09681
  • [Journal Article] 開放隅角緑内障患者における水晶体再建術のコントラスト感度に与える影響2023

    • Author(s)
      関 沙織, 坂田 礼, 朝岡 亮, 秋山 果穂, 齋藤 瞳, 村田 博史, 本庄 恵, 間山 千尋, 相原 一
    • Journal Title

      眼科臨床紀要

      Volume: 16 Pages: 555-560

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Journal Article] Structure Function Relationships of Vessel Density and Retinal Nerve Fiber Layer Thickness in Early Glaucomatous Eyes With High Myopia2023

    • Author(s)
      Akiyama Kaho、Saito Hitomi、Shirato Shiroaki、Iwase Aiko、Aoki Shuichiro、Sugimoto Koichiro、Fujishiro Takashi、Murata Hiroshi、Sakata Rei、Honjo Megumi、Aihara Makoto
    • Journal Title

      Investigative Opthalmology Visual Science

      Volume: 64 Issue: 4 Pages: 14-14

    • DOI

      10.1167/iovs.64.4.14

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Journal Article] Roles of Sphingosine Kinase and Sphingosine-1-Phosphate Receptor 2 in Endotoxin-Induced Acute Retinal Inflammation2023

    • Author(s)
      Ahmed Tazbir、Suzuki Takafumi、Terao Ryo、Yamagishi Reiko、Fujino Ryosuke、Azuma Kunihiro、Soga Hirotsugu、Ueta Takashi、Honjo Megumi、Watanabe Sumiko、Yoshioka Kazuaki、Takuwa Yoh、Aihara Makoto
    • Journal Title

      Ocular Immunology and Inflammation

      Volume: - Issue: 8 Pages: 1-15

    • DOI

      10.1080/09273948.2023.2273963

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Journal Article] 【脂質メディエーターの機能と疾患との関わり】生理活性脂質を介した眼疾患病態と治療2022

    • Author(s)
      相原 一(東京大学 医学部眼科学教室)
    • Journal Title

      Medical Science Digest

      Volume: 48 Pages: 20-23

    • Data Source
      KAKENHI-PROJECT-20H03839
  • [Journal Article] 増殖糖尿病網膜症における硝子体内オートタキシン濃度2022

    • Author(s)
      長岡 泰司, 横田 陽匡, 朝生 浩, 花崎 浩継, 花栗 潤哉, 渡部 昌久, 本庄 恵, 相原 一, 矢倉 裕, 蔵野 信, 五十嵐 浩二, 山上 聡
    • Journal Title

      日本糖尿病眼学会誌

      Volume: 26 Pages: 144-144

    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Journal Article] Newly or switching effect of a selective EP2 agonist on intraocular pressure in Japanese patients with open-angle glaucoma2022

    • Author(s)
      Ueda Koji、Sakata Rei、Fujishiro Takashi、Honjo Megumi、Shirato Shiroaki、Aihara Makoto
    • Journal Title

      Japanese Journal of Ophthalmology

      Volume: 66 Issue: 5 Pages: 434-439

    • DOI

      10.1007/s10384-022-00934-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K09807, KAKENHI-PROJECT-20H03839
  • [Journal Article] The Roles Played by FP/EP3 Receptors During Pressure-lowering in Mouse Eyes Mediated by a Dual FP/EP3 Receptor Agonist2022

    • Author(s)
      Yamagishi-Kimura Reiko、Honjo Megumi、Aihara Makoto
    • Journal Title

      Investigative Opthalmology & Visual Science

      Volume: 63 Issue: 2 Pages: 24-24

    • DOI

      10.1167/iovs.63.2.24

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965, KAKENHI-PROJECT-20H03839
  • [Journal Article] Potential Mechanisms of Intraocular Pressure Reduction by Micropulse Transscleral Cyclophotocoagulation in Rabbit Eyes2022

    • Author(s)
      Nemoto Hotaka、Honjo Megumi、Okamoto Michiaki、Sugimoto Koichiro、Aihara Makoto
    • Journal Title

      Investigative Opthalmology & Visual Science

      Volume: 63 Issue: 6 Pages: 3-3

    • DOI

      10.1167/iovs.63.6.3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K09807, KAKENHI-PROJECT-20H03839
  • [Journal Article] セペタプロストのマウス眼圧に及ぼす作用2022

    • Author(s)
      山岸 麗子(東京大学), 本庄 恵, 相原 一
    • Journal Title

      日本緑内障学会抄録集32回

      Volume: 32 Pages: 77-77

    • Data Source
      KAKENHI-PROJECT-20H03839
  • [Journal Article] Ocular adverse events after COVID-19 mRNA vaccination: matched cohort and self-controlled case series studies using a large database.2022

    • Author(s)
      Hashimoto Y, Yamana H, Iwagami M, Ono S, Takeuchi Y, Michihata N, Uemura K, Yasunaga H, Aihara M, Kaburaki T:
    • Journal Title

      Ophthalmology

      Volume: Oct Issue: 3 Pages: 1-8

    • DOI

      10.1016/j.ophtha.2022.10.017

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09681
  • [Journal Article] Long-term results of the safety and effectiveness of a novel microshunt in Japanese patients with primary open-angle glaucoma2022

    • Author(s)
      Ahmed Tazbir、Honjo Megumi、Sakata Rei、Fujishiro Takashi、Shirato Shiroaki、Aihara Makoto
    • Journal Title

      Japanese Journal of Ophthalmology

      Volume: 66 Issue: 1 Pages: 33-40

    • DOI

      10.1007/s10384-021-00893-x

    • NAID

      40022803285

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09965
  • [Journal Article] Diagnostic ability and sectoral structure function relationship of circumpapillary and macular superficial vessel density in early glaucomatous eyes2022

    • Author(s)
      Akiyama Kaho、Saito Hitomi、Shirato Shiroaki、Iwase Aiko、Sugimoto Koichiro、Fujishiro Takashi、Murata Hiroshi、Sakata Rei、Honjo Megumi、Aihara Makoto
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1

    • DOI

      10.1038/s41598-022-10033-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965, KAKENHI-PROJECT-22K09807
  • [Journal Article] Effect of pigmentation intensity of trabecular meshwork cells on mechanisms of micropulse laser trabeculoplasty2022

    • Author(s)
      Shimizu Shota、Honjo Megumi、Sugimoto Koichiro、Okamoto Michiaki、Aihara Makoto
    • Journal Title

      Scientific Reports

      Volume: 12 Issue: 1

    • DOI

      10.1038/s41598-022-14637-5

    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Journal Article] 緑内障薬物治療のQCストーリー-問題解決に向けた現状把握 緑内障治療薬の創薬ターゲット 新規作用機序の眼圧下降薬開発の現状2022

    • Author(s)
      相原 一(東京大学 医学部眼科学教室)
    • Journal Title

      眼薬理

      Volume: 36

    • Data Source
      KAKENHI-PROJECT-20H03839
  • [Journal Article] Visual cortex damage in a ferret model of ocular hypertension2022

    • Author(s)
      Fujishiro Takashi、Honjo Megumi、Kawasaki Hiroshi、Aihara Makoto
    • Journal Title

      Japanese Journal of Ophthalmology

      Volume: 66 Issue: 2 Pages: 205-212

    • DOI

      10.1007/s10384-022-00901-8

    • NAID

      210000172739

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09965, KAKENHI-PUBLICLY-20H05056, KAKENHI-PROJECT-20H03338, KAKENHI-PROJECT-19K09946, KAKENHI-PROJECT-21K19306
  • [Journal Article] Role of Autotaxin in High Glucose-Induced Human ARPE-19 Cells2022

    • Author(s)
      Liu Yang、Yamagishi Reiko、Honjo Megumi、Kurano Makoto、Yatomi Yutaka、Igarashi Koji、Aihara Makoto
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Issue: 16 Pages: 9181-9181

    • DOI

      10.3390/ijms23169181

    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Journal Article] Fibrotic Response of Human Trabecular Meshwork Cells to Transforming Growth Factor-Beta 3 and Autotaxin in Aqueous Humor2022

    • Author(s)
      Liu Mengxuan、Honjo Megumi、Yamagishi Reiko、Igarashi Nozomi、Nakamura Natsuko、Kurano Makoto、Yatomi Yutaka、Igarashi Koji、Aihara Makoto
    • Journal Title

      Biomolecules

      Volume: 12 Issue: 9 Pages: 1231-1231

    • DOI

      10.3390/biom12091231

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K09807, KAKENHI-PROJECT-20H03839
  • [Journal Article] mTOR阻害薬によるTGF-β2添加に伴うヒト線維柱帯細胞の線維化の抑制効果の可能性2022

    • Author(s)
      五十嵐 希望(東京大学), 本庄 恵, 相原 一
    • Journal Title

      日本緑内障学会抄録集32回

      Volume: 32 Pages: 88-88

    • Data Source
      KAKENHI-PROJECT-20H03839
  • [Journal Article] Changes in corneal endothelial cell density after initial Ex-PRESS drainage device implantation and its relating factors over 3 years2022

    • Author(s)
      Aoyama Yurika、Sakata Rei、Fujishiro Takashi、Honjo Megumi、Shirato Shiroaki、Aihara Makoto
    • Journal Title

      Eye

      Volume: - Issue: 1 Pages: 69-74

    • DOI

      10.1038/s41433-021-01888-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965, KAKENHI-PROJECT-22K09807
  • [Journal Article] Short-term outcomes of micropulse transscleral laser therapy using the revised delivery probe in refractory glaucoma2022

    • Author(s)
      Akiyama Takuya、Fujishiro Takashi、Sugimoto Koichiro、Sakata Rei、Saito Hitomi、Honjo Megumi、Aihara Makoto
    • Journal Title

      Japanese Journal of Ophthalmology

      Volume: 66 Issue: 6 Pages: 549-558

    • DOI

      10.1007/s10384-022-00938-9

    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Journal Article] 閾値下レーザー照射によるヒト培養網膜色素上皮由来のセラミド関連物質産生2022

    • Author(s)
      後藤 大樹(東京大学), 荒木 章之, 白矢 智靖, 上田 高志, 戸塚 清人, 外山 琢, 杉本 宏一郎, 内藤 泰幸, 阿部 均, 加藤 聡, 本庄 恵, 相原 一
    • Journal Title

      日本眼科学会雑誌126巻

      Volume: 126 Pages: 288-288

    • Data Source
      KAKENHI-PROJECT-20H03839
  • [Journal Article] 眼と脂質 眼圧制御と生理活性脂質2022

    • Author(s)
      相原 一(東京大学 医・眼科学)
    • Journal Title

      脂質生化学研究(0285-1520)64巻 Page5(2022.05)

      Volume: 64 Pages: 5-5

    • Data Source
      KAKENHI-PROJECT-20H03839
  • [Journal Article] EP2・FP受容体作動薬の併用による内側・外側血液網膜関門とミクログリアへの影響2022

    • Author(s)
      中村 奈津子, 本庄 恵, 山岸 麗子, 相原 一
    • Journal Title

      眼科臨床紀要

      Volume: 15 Pages: 680-681

    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Journal Article] 正常眼圧緑内障において線維柱帯切除術が散瞳後の眼圧に与える影響2022

    • Author(s)
      上田 晃史, 坂田 礼, 藤田 あさひ, 中島 康介, 藤代 貴志, 本庄 恵, 白土 城照, 相原 一
    • Journal Title

      眼科

      Volume: 64 Pages: 1091-1097

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Journal Article] Evaluation of fornix-based trabeculectomy outcomes in Japanese glaucoma patients based on concrete long-term preoperative data2021

    • Author(s)
      Fujita Asahi、Sakata Rei、Ueda Koji、Nakajima Kosuke、Fujishiro Takashi、Honjo Megumi、Shirato Shiroaki、Aihara Makoto
    • Journal Title

      Japanese Journal of Ophthalmology

      Volume: 65 Issue: 2 Pages: 306-312

    • DOI

      10.1007/s10384-020-00797-2

    • NAID

      40022522798

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965, KAKENHI-PROJECT-18K16945
  • [Journal Article] Mechanical stretch induces Ca2+ influx and extracellular release of PGE2 through Piezo1 activation in trabecular meshwork cells2021

    • Author(s)
      Uchida Takatoshi、Shimizu Shota、Yamagishi Reiko、Tokuoka Suzumi M.、Kita Yoshihiro、Honjo Megumi、Aihara Makoto
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 4044-4044

    • DOI

      10.1038/s41598-021-83713-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965, KAKENHI-PROJECT-20H03839, KAKENHI-PROJECT-18K16946
  • [Journal Article] mTOR inhibitors potentially reduce TGF-β2-induced fibrogenic changes in trabecular meshwork cells2021

    • Author(s)
      Igarashi Nozomi、Honjo Megumi、Aihara Makoto
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 14111-14111

    • DOI

      10.1038/s41598-021-93580-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965, KAKENHI-PROJECT-20H03839
  • [Journal Article] TRPV4 is activated by mechanical stimulation to induce prostaglandins release in trabecular meshwork, lowering intraocular pressure2021

    • Author(s)
      Uchida Takatoshi、Shimizu Shota、Yamagishi Reiko、Tokuoka Suzumi M.、Kita Yoshihiro、Sakata Rei、Honjo Megumi、Aihara Makoto
    • Journal Title

      PLOS ONE

      Volume: 16 Issue: 10 Pages: 0258911-0258911

    • DOI

      10.1371/journal.pone.0258911

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965, KAKENHI-PROJECT-20H03839, KAKENHI-PROJECT-18K16946
  • [Journal Article] Central visual field change after fornix-based trabeculectomy in Japanese normal-tension glaucoma patients managed under 15 mmHg2021

    • Author(s)
      Nakajima Kosuke、Sakata Rei、Ueda Koji、Fujita Asahi、Fujishiro Takashi、Honjo Megumi、Shirato Shiroaki、Aihara Makoto
    • Journal Title

      Graefe's Archive for Clinical and Experimental Ophthalmology

      Volume: 259 Issue: 8 Pages: 2309-2316

    • DOI

      10.1007/s00417-021-05215-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09965, KAKENHI-PROJECT-18K16945
  • [Journal Article] Incidence of Sympathetic Ophthalmia after Inciting Events: A National Database Study in Japan.2021

    • Author(s)
      Hashimoto Y, Matsui H, Michihata N, Ishimaru M, Yasunaga H, Aihara M, Kaburaki T.
    • Journal Title

      Ophthalmology

      Volume: 129 Issue: 3 Pages: 344-352

    • DOI

      10.1016/j.ophtha.2021.09.011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09681, KAKENHI-PROJECT-23K21503
  • [Journal Article] Effects of topical TGF-ホイ1, TGF-ホイ2, ATX, and LPA on IOP elevation and regulation of the conventional aqueous humor outflow pathway2021

    • Author(s)
      Nakamura N, Yamagishi R, Honjo M, Igarashi N, Shimizu S, Aihara M.
    • Journal Title

      Molecular Vision

      Volume: 27 Pages: 61-77

    • Data Source
      KAKENHI-PROJECT-20H03839
  • [Journal Article] Effects of topical TGF-β1, TGF-β2, ATX, and LPA on IOP elevation and regulation of the conventional aqueous humor outflow pathway.2021

    • Author(s)
      Nakamura N, Yamagishi R, Honjo M, Igarashi N, Shimizu S, Aihara M.
    • Journal Title

      Mol Vis.

      Volume: 27 Pages: 61-77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03839
  • [Journal Article] Aqueous autotaxin and TGF-βs are promising diagnostic biomarkers for distinguishing open-angle glaucoma subtypes2021

    • Author(s)
      Igarashi Nozomi、Honjo Megumi、Asaoka Ryo、Kurano Makoto、Yatomi Yutaka、Igarashi Koji、Miyata Kazunori、Kaburaki Toshikatsu、Aihara Makoto
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1

    • DOI

      10.1038/s41598-021-81048-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965, KAKENHI-PROJECT-20H03839
  • [Journal Article] Twelve-month surgical outcome and prognostic factors of stand-alone ab interno trabeculotomy in Japanese patients with open-angle glaucoma2021

    • Author(s)
      Omoto Takashi、Sugiura Aya、Fujishiro Takashi、Asano-Shimizu Kimiko、Sugimoto Koichiro、Sakata Rei、Murata Hiroshi、Asaoka Ryo、Honjo Megumi、Aihara Makoto
    • Journal Title

      PLOS ONE

      Volume: 16 Issue: 1 Pages: 0245015-0245015

    • DOI

      10.1371/journal.pone.0245015

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965, KAKENHI-PROJECT-18K18413
  • [Journal Article] Effects of selective EP2 receptor agonist, omidenepag, on trabecular meshwork cells, Schlemm’s canal endothelial cells and ciliary muscle contraction2021

    • Author(s)
      Nakamura Natsuko、Honjo Megumi、Yamagishi Reiko、Igarashi Nozomi、Sakata Rei、Aihara Makoto
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 16257-16257

    • DOI

      10.1038/s41598-021-95768-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965, KAKENHI-PROJECT-20H03839
  • [Journal Article] Comparison of 12-month surgical outcomes of ab interno trabeculotomy with phacoemulsification between spatula-shaped and dual-blade microhooks2021

    • Author(s)
      Omoto Takashi、Fujishiro Takashi、Asano-Shimizu Kimiko、Sugimoto Koichiro、Sakata Rei、Murata Hiroshi、Asaoka Ryo、Honjo Megumi、Aihara Makoto
    • Journal Title

      Japanese Journal of Ophthalmology

      Volume: - Issue: 3 Pages: 402-408

    • DOI

      10.1007/s10384-020-00806-4

    • NAID

      40022562082

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965
  • [Journal Article] Neuroprotective role of sphingolipid rheostat in excitotoxic retinal ganglion cell death2021

    • Author(s)
      Nakamura Natsuko、Honjo Megumi、Yamagishi Reiko、Kurano Makoto、Yatomi Yutaka、Watanabe Sumiko、Aihara Makoto
    • Journal Title

      Experimental Eye Research

      Volume: 208 Pages: 108623-108623

    • DOI

      10.1016/j.exer.2021.108623

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09965
  • [Journal Article] Clinical features of uveitis in elderly patients in central Tokyo (2013-2018).2021

    • Author(s)
      Shirahama S, Soga H, Tanaka R, Fukunaga H, Izawa H, Komae K, Nakahara H, Kawashima H, Aihara M, Kaburaki T.
    • Journal Title

      Int Ophthalmol.

      Volume: 41 Issue: 5 Pages: 1671-1679

    • DOI

      10.1007/s10792-021-01721-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K09681
  • [Journal Article] Effects of mammalian target of rapamycin inhibitors on fibrosis after trabeculectomy2021

    • Author(s)
      Igarashi Nozomi、Honjo Megumi、Aihara Makoto
    • Journal Title

      Experimental Eye Research

      Volume: 203 Pages: 108421-108421

    • DOI

      10.1016/j.exer.2020.108421

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965
  • [Journal Article] Effects of topical TGF-β1, TGF-β2, ATX, and LPA on IOP elevation and regulation of the conventional aqueous humor outflow2021

    • Author(s)
      Nakamura N, Yamagishi R, Honjo M, Igarashi N, Shimizu S, Aihara M.
    • Journal Title

      Mol Vis

      Volume: 27 Pages: 61-77

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965
  • [Journal Article] The Additive Effect of ROCK Inhibitor on Prostaglandin-Treated Japanese Patients with Glaucoma Indicating 15 mmHg and Under: ROCK U-152021

    • Author(s)
      Sakata Rei、Fujishiro Takashi、Saito Hitomi、Honjo Megumi、Shirato Shiroaki、Aihara Makoto
    • Journal Title

      Advances in Therapy

      Volume: 38 Issue: 7 Pages: 3760-3770

    • DOI

      10.1007/s12325-021-01775-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965, KAKENHI-PROJECT-18K16945
  • [Journal Article] Crosstalk between transforming growth factor β-2 and Autotaxin in trabecular meshwork and different subtypes of glaucoma2021

    • Author(s)
      Igarashi Nozomi、Honjo Megumi、Yamagishi Reiko、Kurano Makoto、Yatomi Yutaka、Igarashi Koji、Kaburaki Toshikatsu、Aihara Makoto
    • Journal Title

      Journal of Biomedical Science

      Volume: 28 Issue: 1 Pages: 47-47

    • DOI

      10.1186/s12929-021-00745-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965, KAKENHI-PROJECT-20H03839, KAKENHI-PROJECT-21K09681
  • [Journal Article] Human U90926 orthologous long non-coding RNA as a novel biomarker for visual prognosis in herpes simplex virus type-1 induced acute retinal necrosis2021

    • Author(s)
      Shirahama Shintaro、Taniue Kenzui、Mitsutomi Shuhei、Tanaka Rie、Kaburaki Toshikatsu、Sato Tomohito、Takeuchi Masaru、Kawashima Hidetoshi、Urade Yoshihiro、Aihara Makoto、Akimitsu Nobuyoshi
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 12164-12164

    • DOI

      10.1038/s41598-021-91340-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09986, KAKENHI-PROJECT-20K09840, KAKENHI-PROJECT-21K09681
  • [Journal Article] Recovery of deepening of the upper eyelid sulcus after switching from prostaglandin FP receptor agonists to EP2 receptor agonist: a 3-month prospective analysis2021

    • Author(s)
      Sakata Rei、Fujishiro Takashi、Saito Hitomi、Nakamura Natsuko、Honjo Megumi、Shirato Shiroaki、Miyamoto Etsuyo、Yamada Yoshiaki、Aihara Makoto
    • Journal Title

      Japanese Journal of Ophthalmology

      Volume: 65 Issue: 5 Pages: 591-597

    • DOI

      10.1007/s10384-021-00855-3

    • NAID

      40022680148

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09965, KAKENHI-PROJECT-18K16945
  • [Journal Article] Incidence and Changing Patterns of Uveitis in Central Tokyo.2021

    • Author(s)
      Suzuki T, Kaburaki T, Tanaka R, Shirahama S, Komae K, Nakahara H, Takamoto M, Kawashima H, Aihara M.
    • Journal Title

      Int Ophthalmol.

      Volume: 41 Issue: 7 Pages: 2377-2388

    • DOI

      10.1007/s10792-021-01791-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21K09681
  • [Journal Article] Late-onset Ocular Toxicity Presenting as Uveitis Caused by Crizotinib2021

    • Author(s)
      Iseki Megumi、Kaburaki Toshikatsu、Aihara Makoto、Sawamura Hiromasa
    • Journal Title

      Neuro-Ophthalmology

      Volume: 46 Issue: 1 Pages: 44-49

    • DOI

      10.1080/01658107.2021.1876099

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K09767, KAKENHI-PROJECT-21K09681
  • [Journal Article] Effect of postoperative corticosteroids on surgical outcome and aqueous autotaxin following combined cataract and microhook ab interno trabeculotomy2021

    • Author(s)
      Honjo Megumi、Yamagishi Reiko、Igarashi Nozomi、Ku Chui Yong、Kurano Makoto、Yatomi Yutaka、Igarashi Koji、Aihara Makoto
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1

    • DOI

      10.1038/s41598-020-80736-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965
  • [Journal Article] Involvement of autotaxin in the pathophysiology of elevated intraocular pressure in Posner-Schlossman syndrome2020

    • Author(s)
      Igarashi Nozomi、Honjo Megumi、Yamagishi Reiko、Kurano Makoto、Yatomi Yutaka、Igarashi Koji、Kaburaki Toshikatsu、Aihara Makoto
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 6265-6265

    • DOI

      10.1038/s41598-020-63284-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09965, KAKENHI-PROJECT-20H03839, KAKENHI-PROJECT-18K09398
  • [Journal Article] Effects of ROCK Inhibitors on Apoptosis of Corneal Endothelial Cells in CMV-Positive Posner?Schlossman Syndrome Patients2020

    • Author(s)
      Igarashi Nozomi、Honjo Megumi、Kaburaki Toshikatsu、Aihara Makoto
    • Journal Title

      Investigative Opthalmology & Visual Science

      Volume: 61 Issue: 10 Pages: 5-5

    • DOI

      10.1167/iovs.61.10.5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965
  • [Journal Article] Structural Changes and Astrocyte Response of the Lateral Geniculate Nucleus in a Ferret Model of Ocular Hypertension2020

    • Author(s)
      Fujishiro Takashi、Honjo Megumi、Kawasaki Hiroshi、Asaoka Ryo、Yamagishi Reiko、Aihara Makoto
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Issue: 4 Pages: 1339-1339

    • DOI

      10.3390/ijms21041339

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965, KAKENHI-PROJECT-19K09946, KAKENHI-PUBLICLY-18H05119, KAKENHI-PROJECT-17H03541, KAKENHI-PUBLICLY-20H05056, KAKENHI-PROJECT-20H03338
  • [Journal Article] 緑内障点眼薬の使い方を整理する2020

    • Author(s)
      本庄 恵, 相原 一
    • Journal Title

      OCULISTA

      Volume: 87 Pages: 71-77

    • Data Source
      KAKENHI-PROJECT-19K09965
  • [Journal Article] Comparison of the short-term effectiveness and safety profile of ab interno combined trabeculotomy using 2 types of trabecular hooks2020

    • Author(s)
      Omoto Takashi、Fujishiro Takashi、Asano-Shimizu Kimiko、Sugimoto Koichiro、Sakata Rei、Murata Hiroshi、Asaoka Ryo、Honjo Megumi、Aihara Makoto
    • Journal Title

      Japanese Journal of Ophthalmology

      Volume: 64 Issue: 4 Pages: 407-413

    • DOI

      10.1007/s10384-020-00750-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965
  • [Journal Article] Activation of the Sphingosine 1 Phosphate?Rho Pathway in Pterygium and in Ultraviolet-Irradiated Normal Conjunctiva2019

    • Author(s)
      Igarashi Nozomi、Honjo Megumi、Fujishiro Takashi、Toyono Tetsuya、Ono Takashi、Mori Yosai、Miyata Kazunori、Obinata Hideru、Aihara Makoto
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 20 Issue: 19 Pages: 4670-4670

    • DOI

      10.3390/ijms20194670

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965
  • [Journal Article] Development of a Novel Intraocular-Pressure-Lowering Therapy Targeting ATX2019

    • Author(s)
      Nagano Norimichi、Honjo Megumi、Kawaguchi Mitsuyasu、Nishimasu Hiroshi、Nureki Osamu、Kano Kuniyuki、Aoki Junken、Komatsu Toru、Okabe Takayoshi、Kojima Hirotatsu、Nagano Tetsuo、Aihara Makoto
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 42 Issue: 11 Pages: 1926-1935

    • DOI

      10.1248/bpb.b19-00567

    • NAID

      130007740593

    • ISSN
      0918-6158, 1347-5215
    • Year and Date
      2019-11-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965, KAKENHI-PROJECT-18K14358
  • [Journal Article] The role of sphingosine 1-phosphate receptors on retinal pigment epithelial cells barrier function and angiogenic effects2019

    • Author(s)
      Terao Ryo、Honjo Megumi、Totsuka Kiyohito、Miwa Yukihiro、Kurihara Toshihide、Aihara Makoto
    • Journal Title

      Prostaglandins & Other Lipid Mediators

      Volume: 145 Pages: 106365-106365

    • DOI

      10.1016/j.prostaglandins.2019.106365

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965, KAKENHI-PROJECT-18K09424
  • [Journal Article] The Neuroprotective Effect of the Adiponectin Receptor Agonist AdipoRon on Glutamate-Induced Cell Death in Rat Primary Retinal Ganglion Cells2019

    • Author(s)
      Uchida Takatoshi、Ueta Takashi、Honjo Megumi、Aihara Makoto
    • Journal Title

      Journal of Ocular Pharmacology and Therapeutics

      Volume: 35 Issue: 10 Pages: 535-541

    • DOI

      10.1089/jop.2018.0152

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09965
  • [Journal Article] Induction of amyloid-β1-42 in the retina and optic nerve head of chronic ocular hypertensive monkeys2012

    • Author(s)
      Ito Y, Shimazawa M, Tsuruma K, Mayama C, Ishii K, Onoe H, Aihara M, Araie M, Hara H
    • Journal Title

      Molecular Vision

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390321
  • [Journal Article] Involvement of endoplasmic reticulum stress in optic nerve degeneration following N-methyl-D-aspartate-induced retinal damage in mice.2012

    • Author(s)
      Shimazawa M, Miwa A, Ito Y, Tsuruma K, Aihara M, Hara H.
    • Journal Title

      Journal of Neuroscience Research

      Volume: 90 Issue: 10 Pages: 1960-1969

    • DOI

      10.1002/jnr.23078

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390321
  • [Journal Article] Involvement of endoplasmic reticulum stress in optic nerve degeneration following N-methyl-D-aspartate-induced retinal damage in mice2012

    • Author(s)
      Shimazawa M, Miwa A, Ito Y, Tsuruma K, Aihara M, Hara H
    • Journal Title

      Journal of Neuroscience Research

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390321
  • [Journal Article] Involvement of endoplasmic reticulum stress on neuronal cell death in the lateral geniculate nucleus in the monkey glaucoma model2011

    • Author(s)
      Ito Y, Shimazawa M, Inokuchi Y, Yamanaka H, Tsuruma K, Imamura K, Onoe H, Watanabe Y, Aihara M, Araie M, Hara H
    • Journal Title

      European Journal of Neuroscience

      Volume: 33 Issue: 5 Pages: 843-55

    • DOI

      10.1111/j.1460-9568.2010.07578.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390321, KAKENHI-PROJECT-22500311
  • [Journal Article] Involvement of endoplasmic reticulum stress on neuronal cell death in the lateral geniculate nucleus in the monkey glaucoma model.2011

    • Author(s)
      Ito Y, Shimazawa M, Inokuchi Y, Yamanaka H, Tsuruma K, Imamura K, Onoe H, Watanabe Y, Aihara M, Araie M, Hara H.
    • Journal Title

      Europian Journal of Neuroscience

      Volume: 33 Pages: 843-855

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390321
  • [Journal Article] Neuroprotective Effects Of Prostaglandin Analogues On Retinal Ganglion Cell Death Independent Of Intraocular Pressure Reduction2011

    • Author(s)
      Yamagishi R, Aihara M, Chen YN, Araie M
    • Journal Title

      Experimental Eye Research

      Volume: 93 Pages: 265-70

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390321
  • [Journal Article] Neuroprotective effects of flavonoids on hypoxia-, glutamate-, and oxidative stress-induced retinal ganglion cell death2011

    • Author(s)
      Nakayama M, Aihara M, Chen YN, Araie M, Tomita-Yokotani K, Iwashina T.
    • Journal Title

      Molecular Vision

      Volume: (In press)(掲載確定)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390321
  • [Journal Article] Effects of Bax-inhibiting Peptides in Retinal Ganglion Cell Death Induced by Glutamate or Oxidative Stress In2009

    • Author(s)
      Chen YN, Aihara M, Mao W, Yamada H, Matsuyama S, Araie M
    • Journal Title

      Vitro Brain Res 1148

      Pages: 28-37

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209053
  • [Journal Article] Effect of an inducer of BiP, a molecular chaperone, on endoplasmic reticulum(ER)stress-induced retinal cell death2009

    • Author(s)
      nokuchi Y, Nakajima Y, Shimazawa M, Kurita T, Kubo M, Saito A, Sajiki H, Kudo T, Aihara M, Imaizumi K, Araie M, Hara H.
    • Journal Title

      Invest Opthamol Vis Sci 50

      Pages: 334-344

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209053
  • [Journal Article] Effects of prostanoid EP agonists on mouse intraocular pressure.2009

    • Author(s)
      Saeki T, Ota T, Aihara M, Araie M.
    • Journal Title

      nvest Opthamol Vis Sci 50

      Pages: 2201-2208

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209053
  • [Journal Article] Imaging Mouse Retinal Ganglion Cells and Their Loss in vivo by a Fundus Camera in the Normal and Ischemia-Reperfusion Model2008

    • Author(s)
      Murata H, Aihara M, Chen YN, Ota T, Numaga J, Araie M
    • Journal Title

      Invest Ophthalmol Vis Sci 49

      Pages: 5546-5552

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209053
  • [Journal Article] Imaging mouse retinal ganglion cells and their loss in vivo by a fundus camera in the normal and ischemia-reperfusion model.2008

    • Author(s)
      Murata H, Aihara M, Chen YN, Ota T, Numaga J, Araie M.
    • Journal Title

      Invest Opthamol Vis Sci 49

      Pages: 5546-52

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209053
  • [Journal Article] Involvement of ER stress in retinal cell death2007

    • Author(s)
      Shimazawa M, Inokuchi Y, Ito Y, Murata H, Aihara M, Miura M, Araie M and Hara H
    • Journal Title

      Mol Vis 13

      Pages: 578-587

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209053
  • [Journal Article] Effects of beta-adrenergic receptor antagonists on oxidative stress in purified rat retinal ganglion cells2007

    • Author(s)
      Yu ZK, Chen YN, Aihara M, Mao W, Uchida S, Araie M
    • Journal Title

      Mol Vis 13

      Pages: 833-90

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209053
  • [Journal Article] Hypoxia-lnduced Retinal Ganglion Cell Death and the Neuroprotective Effects of Beta-adrenergic Antagonists2007

    • Author(s)
      Yi-Ning Chen, Hideyuki Yamada, Wei Mao, Shigemi Matsuyama, Makoto Aihara, Makoto Araie.
    • Journal Title

      Brain Res 7

      Pages: 28-37

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18209053
  • [Journal Article] Plotelet-activating Factor synthesizes by hippocampal neuron induces chemotaxis of microglia in culture2000

    • Author(s)
      Aihara M, Ishii S, Kume U, Shimizu T.
    • Journal Title

      Genes to Cells 5

      Pages: 397-406

    • Data Source
      KAKENHI-PROJECT-10557153
  • [Presentation] 緑内障患者に対するプリザーフロマイクロシャント後の角膜内皮細胞密度の評価2023

    • Author(s)
      山江晃生、坂田礼、石山由佳子、鈴木陽之、杉本宏一郎、藤代貴志、齋藤瞳、本庄恵、白土城照、相原一
    • Organizer
      第34回日本緑内障学会
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Presentation] Taoka K, Shimura A, Tanaka R, Honda A, Masamoto Y, Kaburaki T, Aihara M, Kurokawa M.2023

    • Author(s)
      Taoka K, Shimura A, Tanaka R, Honda A, Masamoto Y, Kaburaki T, Aihara M, Kurokawa M.
    • Organizer
      第85回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K09681
  • [Presentation] Incidence of sympathetic ophthalmia after ocular trauma and surgeries: a national database study in Japan.2023

    • Author(s)
      Kaburaki T, Hashimoto Y, Matsui Y, Michihata N, Ishimaru M, Yasunaga H, Aihara M.
    • Organizer
      International Ocular Inflammation Society Meeting 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09681
  • [Presentation] 緑内障患者に対するプリザーフロマイクロシャント術後の角膜惹起乱視の評価2023

    • Author(s)
      石山由佳子、坂田礼、鈴木陽之、山江晃生、杉本宏一郎、藤代貴志、齋藤瞳、本庄恵、白土城照、相原一
    • Organizer
      第34回日本緑内障学会
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Presentation] 緑内障患者に対するプリザーフロマイクロシャントの有効性と安全性.2023

    • Author(s)
      鈴木陽之、坂田礼、石山由佳子、山江晃生、杉本宏一郎、藤代貴志、齋藤瞳、本庄恵、白土城照、相原一
    • Organizer
      第34回日本緑内障学会
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Presentation] 小胞体ストレスによるヒト線維柱帯細胞への影響とROCK阻害薬の作用2023

    • Author(s)
      Liu Mengxuan、Honjo Megumi、Yamagishi Reiko、Aihara Makoto.
    • Organizer
      第127回日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-23K27749
  • [Presentation] Apoptosis inhibitor of macrophage(AIM)の繊維柱帯細胞貧食能への関与2023

    • Author(s)
      根本穂高、本庄恵、新井郷子、宮崎徹、相原一
    • Organizer
      第127回日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Presentation] Peripapillary intrachoroidal cavitationを有する眼の臨床的特徴と視野障害に関連する因子の検討2023

    • Author(s)
      秋山果穂、 齋藤瞳、白土城照、青木修一郎、杉本宏一郎、藤代貴志、坂田礼、本庄恵、相原一
    • Organizer
      第34回日本緑内障学会
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Presentation] EX-PRESS挿入術後の診察回数と術後経過の関係2023

    • Author(s)
      青山祐里香、藤代貴志、坂田礼、齋藤瞳、本庄恵、相原一
    • Organizer
      第127回日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Presentation] 眼内でのautotaxin発現誘導による開放隅角高眼圧マウスモデルの確立2023

    • Author(s)
      清水翔太、本庄恵、Liu Mengxuan、相原一.
    • Organizer
      第127回日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Presentation] 眼内でのautotaxin発現誘導による開放隅角高眼圧マウスモデルの確立2023

    • Author(s)
      清水翔太、本庄恵、Liu Mengxuan、相原一
    • Organizer
      第127回日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-23K27749
  • [Presentation] Apoptosis inhibitor of macrophage(AIM)の繊維柱帯細胞貧食能への関与2023

    • Author(s)
      根本穂高、本庄恵、新井郷子、宮崎徹、相原一
    • Organizer
      第127回日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-23K27749
  • [Presentation] 正常眼の乳頭周囲血管密度測定における眼軸長と拡大率補正の影響の検討2023

    • Author(s)
      秋山果穂、齋藤瞳、青木修一郎、白土城照、岩瀬愛子、杉本宏一郎、藤代貴志、村田博史、坂田礼、本庄恵、相原一
    • Organizer
      第127回日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Presentation] 線維柱帯細胞のAIMを介した貪食能と眼圧上昇制御機序への関与の解明.2023

    • Author(s)
      根本穂高、本庄恵、新井郷子、宮崎徹、相原一
    • Organizer
      第34回日本緑内障学会:
    • Data Source
      KAKENHI-PROJECT-23K27749
  • [Presentation] 閾値下レーザー照射によるヒト培養網膜色素上皮由来のセラミド関連物質産生2022

    • Author(s)
      後藤 大樹, 荒木 章之, 白矢 智靖, 上田 高志, 戸塚 清人, 外山 琢, 杉本 宏一郎, 内藤 泰幸, 阿部 均, 加藤 聡, 本庄 恵, 相原 一
    • Organizer
      第126回日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Presentation] 改良型プローブによるマイクロパルスレーザー毛様体光凝固術の6ヵ月治療成績2022

    • Author(s)
      武田 尚子, 藤代 貴志, 杉本 宏一郎, 坂田 礼, 斎藤 瞳, 本庄 恵, 相原 一
    • Organizer
      第126回日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Presentation] Apoptosis inhibitor of macrophage(AIM)の線維柱帯細胞貪食能への関与2022

    • Author(s)
      根本 穂高, 本庄 恵, 新井 郷子, 宮崎 徹, 相原 一
    • Organizer
      第126回日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Presentation] Involvement of autotaxin in the pathophysiology of elevated intraocular pressure in Posner-Schlossman syndrome2022

    • Author(s)
      五十嵐希望、山岸麗子、本庄恵、相原一
    • Organizer
      第126回日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-20H03839
  • [Presentation] 開放隅角緑内障に対するマイクロパルスレーザー線維柱帯形成術と選択的レーザー線維柱帯形成術の長期成績2022

    • Author(s)
      馬場口 紘成, 藤代 貴志, 杉本 宏一郎, 坂田 礼, 齋藤 瞳, 本庄 恵, 相原 一
    • Organizer
      第33回日本緑内障学会
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Presentation] 開放隅角緑内障患者のコントラスト感度に与える白内障手術の影響2022

    • Author(s)
      関 沙織 坂田 礼, 朝岡 亮, 村田 博史, 本庄 恵, 間山 千尋, 相原 一
    • Organizer
      第126回日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Presentation] 各種眼圧下降薬のマウス上強膜静脈圧に及ぼす作用2022

    • Author(s)
      山岸 麗子, 本庄 恵, 相原 一
    • Organizer
      第33回日本緑内障学会
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Presentation] グルタミン酸誘発網膜神経障害に対するグリア細胞を介したomidenepagの間接的保護効果2022

    • Author(s)
      中村 奈津子, 本庄 恵, 山岸 麗子, 相原 一
    • Organizer
      第126回日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Presentation] 長眼軸眼に対する水晶体再建術併用線維柱帯切開術眼内法の短期成績の検討2022

    • Author(s)
      後藤 大樹, 大本 貴士, 杉本 宏一郎, 藤代 貴志, 坂田 礼, 齋藤 瞳, 本庄 恵, 相原 一
    • Organizer
      第33回日本緑内障学会
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Presentation] COVID-19ワクチン接種後の眼有害事象 マッチト・コホート研究 & 自己対照ケースシリーズ研究..2022

    • Author(s)
      橋本洋平、山名隼人、岩上将夫、大野幸子、竹内由則、道端伸明、上村鋼平、永秀生、相原一、蕪城俊克.
    • Organizer
      日本臨床疫学会第5回年次学術大会
    • Data Source
      KAKENHI-PROJECT-21K09681
  • [Presentation] 強度近視早期緑内障眼におけるOCTAで測定された血管密度と中心視野の検討2022

    • Author(s)
      秋山 果穂, 齋藤 瞳, 白土 城照, 岩瀬 愛子, 杉本 宏一郎, 藤代 貴志, 村田 博史, 坂田 礼, 本庄 恵, 相原 一
    • Organizer
      第33回日本緑内障学会
    • Data Source
      KAKENHI-PROJECT-22K09807
  • [Presentation] 眼圧制御と緑内障病型におけるオートタキシン-リゾフォスファチジン酸経路およびmTORの関与2021

    • Author(s)
      五十嵐希望、山岸麗子、本庄恵、相原一
    • Organizer
      第32回日本緑内障学会
    • Data Source
      KAKENHI-PROJECT-20H03839
  • [Presentation] 緑内障病型におけるTGF-β2とAutotaxinのクロストーク2021

    • Author(s)
      五十嵐希望、山岸麗子、本庄恵、相原一
    • Organizer
      第32回日本緑内障学会
    • Data Source
      KAKENHI-PROJECT-20H03839
  • [Presentation] 落屑緑内障における房水中TGF-β、ATX-LPAシグナルと眼圧、重症度との相関の検討、多施設共同研究2021

    • Author(s)
      本庄恵、五十嵐希望、山岸麗子、相原一
    • Organizer
      第32回日本緑内障学会
    • Data Source
      KAKENHI-PROJECT-20H03839
  • [Presentation] 緑内障②おける前房水中のTGFβとautotaxinの関連2021

    • Author(s)
      五十嵐希望、本庄恵、山岸麗子、蔵野信、矢冨裕、五十嵐浩二、相原一
    • Organizer
      124回日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-20H03839
  • [Presentation] IOP-lowering effect of FP/EP3 receptor agonist in mouse eye2021

    • Author(s)
      山岸麗子、本庄恵、五十嵐希望、相原一
    • Organizer
      第32回日本緑内障学会
    • Data Source
      KAKENHI-PROJECT-20H03839
  • [Presentation] IOP-lowering effect of FP/EP3 receptor agonist in mouse eye2021

    • Author(s)
      山岸麗子、本庄恵、相原一
    • Organizer
      第32回日本緑内障学会
    • Data Source
      KAKENHI-PROJECT-19K09965
  • [Presentation] Aqueous autotaxin and TGF-βs are promising diagNOstic biomarkers for distinguishing open-angle glaucoma subtypes2021

    • Author(s)
      五十嵐希望、山岸麗子、本庄恵、相原一
    • Organizer
      World Glaucoma Congress 2021
    • Data Source
      KAKENHI-PROJECT-20H03839
  • [Presentation] mTOR阻害薬によるTGF-β2添加に伴うヒト線維柱帯細胞の線維化の抑制効果の可能性2021

    • Author(s)
      五十嵐希望、山岸麗子、本庄恵、相原一
    • Organizer
      第32回日本緑内障学会
    • Data Source
      KAKENHI-PROJECT-20H03839
  • [Presentation] Trabecular Meshwork Scarring & ROCK inhibitors2021

    • Author(s)
      本庄恵、五十嵐希望、山岸麗子、相原一
    • Organizer
      World Glaucoma Congress 2021
    • Data Source
      KAKENHI-PROJECT-20H03839
  • [Presentation] MicroShuntを用いた日本人緑内障に対する濾過手術MIGSの長期経過2020

    • Author(s)
      本庄 恵, 相原 一, 坂田 礼, 藤代 貴志, 白土 城照
    • Organizer
      日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-19K09965
  • [Presentation] 日本人緑内障患者に対するオミデネパグ・イソプロピルの新規投与 眼圧変化と副作用2020

    • Author(s)
      坂田 礼, 藤代 貴志, 本庄 恵, 上田 晃史, 白土 城照, 相原 一
    • Organizer
      日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-19K09965
  • [Presentation] EP2受容体作動薬オミデネパグイソプロピルへの切り替えによる短期的有効性安全性評価2020

    • Author(s)
      上田 晃史(東京大学), 坂田 礼, 藤代 貴志, 本庄 恵, 白土 城照, 相原 一
    • Organizer
      日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-19K09965
  • [Presentation] 原発開放隅角緑内障と落屑緑内障に対する眼内法線維柱帯切開単独手術の1年治療成績2020

    • Author(s)
      緒方 南友美, 藤代 貴志, 大本 貴士, 杉本 宏一郎, 坂田 礼, 村田 博史, 本庄 恵, 相原 一
    • Organizer
      日本緑内障学会
    • Data Source
      KAKENHI-PROJECT-19K09965
  • [Presentation] 緑内障における前房水中のTGFβとautotaxinの関連2020

    • Author(s)
      五十嵐 希望, 本庄 恵, 山岸 麗子, 蔵野 信, 矢冨 裕, 五十嵐 浩二, 相原 一
    • Organizer
      日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-19K09965
  • [Presentation] OmidenepagとLatanoprost併用による外側網膜血液関門への影響2020

    • Author(s)
      中村 奈津子, 本庄 恵, 山岸 麗子, 相原 一
    • Organizer
      日本緑内障学会
    • Data Source
      KAKENHI-PROJECT-19K09965
  • [Presentation] ATXおよびLPAのシュレム管内皮バリア機能への関与とそれに対するROCK阻害剤の作用2020

    • Author(s)
      山岸 麗子, 本庄 恵, 相原 一
    • Organizer
      日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-19K09965
  • [Presentation] 日本人緑内障患者に対するEX-PRESS術後の角膜内皮細胞密度の長期的経過について2020

    • Author(s)
      青山 祐里香, 坂田 礼, 藤代 貴志, 本庄 恵, 白土 城照, 相原 一
    • Organizer
      日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-19K09965
  • [Presentation] Microshuntを用いた日本人緑内障に対する濾過手術MIGSの長期経過2019

    • Author(s)
      相原一、本庄恵、他
    • Organizer
      第30回日本緑内障学会
    • Data Source
      KAKENHI-PROJECT-19K09965
  • [Presentation] Central corneal thickness.2015

    • Author(s)
      Suga M, Yoshida T, Aihara M, Ohno-Matsui K.
    • Organizer
      World Glaucoma Congress 2015.
    • Place of Presentation
      Hong Kong (China)
    • Year and Date
      2015-06-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K15629
  • [Presentation] Roles for 53BP1, a DNA damage response protein, in retinal ganglion cell survival2014

    • Author(s)
      Mari Katsura, Reiko Yamagishi, Makoto Aihara
    • Organizer
      World Ophthalmology Congress 2014
    • Place of Presentation
      東京国際フォーラム
    • Data Source
      KAKENHI-PROJECT-23592553
  • [Presentation] Roles for methylation of H4K20 and 53BP1 in hypoxia-induced retinal ganglion cell death2014

    • Author(s)
      Mari Katsura, Reiko Yamagishi, Makoto Aihara
    • Organizer
      ARVO 2014
    • Place of Presentation
      オーランド(米国)Orange Country Convention Center
    • Data Source
      KAKENHI-PROJECT-23592553
  • [Presentation] 網膜神経節細胞死におけるヒストンH4K20モノメチル化の役割2014

    • Author(s)
      桂真理、山岸麗子、和田洋一郎、相原一
    • Organizer
      第118回日本眼科学会学術総会
    • Place of Presentation
      東京国際フォーラム
    • Data Source
      KAKENHI-PROJECT-23592553
  • [Presentation] Vav2欠損CFP発現遺伝子改変マウスを用いた眼圧の影響とRGC障害の解析2014

    • Author(s)
      藤川恵子、井上馨、越山隆恵、山岸麗子、相原一
    • Organizer
      第118回日本眼科学会
    • Data Source
      KAKENHI-PROJECT-23592549
  • [Presentation] Roles for 53BP1, a DNA damage response protein, in retinal ganglion cell survival2014

    • Author(s)
      Mari Katsura, Reiko Yamagishi, Makoto Aihara
    • Organizer
      World Ophthalmology Congress 2014
    • Place of Presentation
      東京国際フォーラム(東京)
    • Data Source
      KAKENHI-PROJECT-23592553
  • [Presentation] Characterization of CFP-expressed Vav2-deficient mice with spontaneous2014

    • Author(s)
      Fujikawa K, Inoue K, Koshiyama T, Yamagishi R, Aihara M
    • Organizer
      IOP elevation to evaluate pressure-dependent RGC death
    • Place of Presentation
      ARVO, Orlando, FL, USA
    • Data Source
      KAKENHI-PROJECT-23592549
  • [Presentation] Vav2 欠損CFP発現遺伝子改変マウスを用いた眼圧の影響とRGC障害の解析2014

    • Author(s)
      藤川恵子、井上馨、越山隆恵、山岸麗子、相原一
    • Organizer
      第118回日本眼科学会総会
    • Place of Presentation
      国際フォーラム、東京
    • Data Source
      KAKENHI-PROJECT-23592549
  • [Presentation] 網膜神経節細胞死におけるヒストンH4K20モノメチル化の役割2014

    • Author(s)
      桂真理、山岸麗子、和田洋一郎、相原一
    • Organizer
      第118回日本眼科学会学術総会
    • Place of Presentation
      東京国際フォーラム(東京)
    • Data Source
      KAKENHI-PROJECT-23592553
  • [Presentation] Characterization of CFP-expressed Vav2-deficient mice with spontaneous IOP elevation to evaluate pressure-dependent RGC death2014

    • Author(s)
      Keiko Fujikawa, Kaoru Inoue, Takae Koshiyama, Reiko Yamagishi, Makoto Aihara
    • Organizer
      2014 ARVO meeting
    • Place of Presentation
      Orlando Convention Center, Orlando FL, USA
    • Data Source
      KAKENHI-PROJECT-23592549
  • [Presentation] Roles for methylation of H4K20 and 53BP1 in hypoxia- induced retinal ganglion cell death2014

    • Author(s)
      Mari Katsura, Reiko Yamagishi, Makoto Aihara
    • Organizer
      ARVO 2014
    • Place of Presentation
      Orange Country Convention Center(オーランド・アメリカ)
    • Data Source
      KAKENHI-PROJECT-23592553
  • [Presentation] 自然発症高眼圧を呈するVav遺伝子欠損マウスの眼圧の特徴2013

    • Author(s)
      藤川恵子、井上馨、越山隆恵、山岸麗子、相原一
    • Organizer
      第117回日本眼科学会
    • Data Source
      KAKENHI-PROJECT-23592549
  • [Presentation] 網膜神経節細胞における低酸素負荷時のNFkBのリン酸化とラタノプロストの役割2013

    • Author(s)
      桂真理、山岸麗子、相原一
    • Organizer
      第117回日本眼科学会学術総会
    • Place of Presentation
      東京国際フォーラム(東京)
    • Data Source
      KAKENHI-PROJECT-23592553
  • [Presentation] Mechanisms of Neuroprptection by Latanoprost for Retinal Ganglion Cells under Hypoxia2013

    • Author(s)
      Mari Katsura, Reiko Yamagishi, Makoto Aihara
    • Organizer
      ARVO 2013
    • Place of Presentation
      シアトル(米国)Washington State Convention Center
    • Data Source
      KAKENHI-PROJECT-23592553
  • [Presentation] 自然発症高眼圧を呈するVav遺伝子欠損マウスの眼圧の特徴2013

    • Author(s)
      藤川恵子、井上馨、越山隆恵、 相原一、山岸麗
    • Organizer
      日本眼科学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23592549
  • [Presentation] 低酸素誘導神経細胞師における53BP1の役割2013

    • Author(s)
      天笠翔太、桂真理、秋光信佳、相原一、宮川清、和田洋一郎
    • Organizer
      第56回放射線影響学会
    • Place of Presentation
      青森ホテルクラウンパレス(青森)
    • Data Source
      KAKENHI-PROJECT-23592553
  • [Presentation] Mechanisms of Neuroprptection by Latanoprost for Retinal Ganglion Cells under Hypoxia2013

    • Author(s)
      Mari Katsura, Reiko Yamagishi, Makoto Aihara
    • Organizer
      ARVO 2013
    • Place of Presentation
      Washington State Convention Center(シアトル・アメリカ)
    • Data Source
      KAKENHI-PROJECT-23592553
  • [Presentation] 網膜神経節細胞におけるヒストンH4K20メチル化と53BP1の役割2013

    • Author(s)
      桂真理、天笠翔太、山岸麗子、相原一、児玉龍彦、和田洋一郎、秋光信佳、宮川清
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸ポートアイランド(兵庫)
    • Data Source
      KAKENHI-PROJECT-23592553
  • [Presentation] 低酸素誘導神経細胞師における53BP1の役割2013

    • Author(s)
      天笠翔太、桂真理、秋光信佳、相原一、宮川清、和田洋一郎
    • Organizer
      第56回放射線影響学会
    • Place of Presentation
      青森 ホテルクラウンパレス
    • Data Source
      KAKENHI-PROJECT-23592553
  • [Presentation] 低酸素負荷神経節細胞死におけるDNA損傷応答の役割2013

    • Author(s)
      桂真理、山岸麗子、仲嶺宏政、天笠翔太、秋光信佳、曽根秀子、和田洋一郎、相原一
    • Organizer
      第24回日本緑内障学会
    • Place of Presentation
      京王プラザホテル(新宿)
    • Data Source
      KAKENHI-PROJECT-23592553
  • [Presentation] 網膜神経節細胞における低酸素負荷時のNFkBのリン酸化とラタノプロストの役割2013

    • Author(s)
      桂真理、山岸麗子、相原一
    • Organizer
      第117回日本眼科学会学術総会
    • Place of Presentation
      東京国際フォーラム
    • Data Source
      KAKENHI-PROJECT-23592553
  • [Presentation] 網膜神経節細胞におけるヒストンH4K20メチル化と53BP1の役割2013

    • Author(s)
      桂真理、天笠翔太、山岸麗子、相原一、児玉龍彦、和田洋一郎、秋光信佳、宮川清
    • Organizer
      第36回日本分子生物学会年会
    • Place of Presentation
      神戸ポートアイランド
    • Data Source
      KAKENHI-PROJECT-23592553
  • [Presentation] The Roles for DNA Damage Response in Retinal Ganglion Cell Death2012

    • Author(s)
      Mari Katsura, Makoto Aihara, Reiko Yamagishi, et al.
    • Organizer
      ARVO 2012
    • Place of Presentation
      ブロワードカントリーコンベンションセンター(フォートローダーディール・アメリカ)
    • Data Source
      KAKENHI-PROJECT-23592553
  • [Presentation] 低酸素誘導網膜神経細胞死における DNA損傷応答の役割2012

    • Author(s)
      桂 真理、山岸麗子、嶋澤雅光、原 英彰、相原 一
    • Organizer
      第116回日本眼科学会学術総会
    • Place of Presentation
      東京フォーラム(東京都)
    • Data Source
      KAKENHI-PROJECT-23592553
  • [Presentation] The Roles for DNA Damage Response in Retinal Ganglion Cell Death2012

    • Author(s)
      Mari Katsura, Makoto Aihara, Reiko Yamagishi, et al
    • Organizer
      ARVO 2012
    • Place of Presentation
      ブロワードカントリーコンベンションセンター(フォートローダーディール・アメリカ)
    • Data Source
      KAKENHI-PROJECT-23592553
  • [Presentation] 低酸素誘導網膜神経細胞死におけるDNA損傷応答の役割2012

    • Author(s)
      桂真理、山岸麗子、嶋澤雅光、原英彰、相原一
    • Organizer
      第116回日本眼科学会学術総会
    • Place of Presentation
      東京国際フォーラム(東京)
    • Data Source
      KAKENHI-PROJECT-23592553
  • [Presentation] NA Damage Response in Retinal Ganglion Cells2011

    • Author(s)
      桂真理、山岸麗子、相原一
    • Organizer
      World Congress of Glaucoma 2011
    • Place of Presentation
      パレ・デ・コングレ(フランス)
    • Year and Date
      2011-06-29
    • Data Source
      KAKENHI-PROJECT-23592553
  • [Presentation] ラット網膜神経節細胞初代培養を用いたグルタミン酸負荷下でのプロスタグランジン関連眼圧下降薬の細胞保護作用2010

    • Author(s)
      山岸麗子、相原一、新家眞
    • Organizer
      日本緑内障学会
    • Place of Presentation
      福岡
    • Year and Date
      2010-09-26
    • Data Source
      KAKENHI-PROJECT-22390321
  • [Presentation] フェレット高眼圧モデルにおける外側膝状体(LGN)の組織学的解析2010

    • Author(s)
      藤代貴志、佐伯忠賜朗、新卓也、河崎洋志、相原一、新家眞
    • Organizer
      日本緑内障学会
    • Place of Presentation
      福岡
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-22390321
  • [Presentation] CFP発現マウスを用いた視神経におけるレチノトピー2009

    • Author(s)
      鶴我英和、村田博史、相原一、新家 眞
    • Organizer
      第113回日本眼科学会総会
    • Place of Presentation
      東京都
    • Year and Date
      2009-04-16
    • Data Source
      KAKENHI-PROJECT-18209053
  • [Presentation] マウス正常眼における網膜神経節細胞の減少率2009

    • Author(s)
      村田博史、相原-、新家 眞
    • Organizer
      第113回日本眼科学会総会
    • Place of Presentation
      東京都
    • Year and Date
      2009-04-16
    • Data Source
      KAKENHI-PROJECT-18209053
  • [Presentation] CFP発現マウスを用いた眼圧依存性網膜神経節細胞障害の評価2008

    • Author(s)
      鶴我英和、村田博史、相原一、新家 眞
    • Organizer
      第112回日本眼科学会総会
    • Place of Presentation
      横浜市
    • Year and Date
      2008-04-18
    • Data Source
      KAKENHI-PROJECT-18209053
  • [Presentation] フラボノイドの網膜神経節細胞保護効果2008

    • Author(s)
      毛い、佐伯忠志朗、陳逸寧、相原一、新家 眞
    • Organizer
      第112回日本眼科学会総会
    • Place of Presentation
      横浜市
    • Year and Date
      2008-04-18
    • Data Source
      KAKENHI-PROJECT-18209053
  • [Presentation] pitavastatin(NK104)のラット網膜神経節細胞保護効果2006

    • Author(s)
      毛蔚, 陳逸寧, 相原一, 新家眞. Et.al.
    • Organizer
      第26回眼薬理学会
    • Place of Presentation
      福井
    • Data Source
      KAKENHI-PROJECT-18209053
  • [Presentation] 虚血再灌流モデルを用いた生体内網膜神経節細胞の経時的変化の評価2006

    • Author(s)
      村田博史, 陳逸寧, 太田貴史, 相原一, 新家眞
    • Organizer
      第17回日本緑内障学会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-18209053
  • [Presentation] pitavastatin のラット網膜神経節細胞保護効果2006

    • Author(s)
      毛蔚, 陳逸寧, 相原一, 新家眞. Et.al.
    • Organizer
      Ophthalmoneuroprotection
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-18209053
  • [Presentation] Characterization of CFP-expressed Vav2-deficient mice with spontaneous IOP elevation to evaluate pressure-dependent RGC death

    • Author(s)
      Keiko Fujikawa、Kaoru Inoue、Reiko Yamagishi、 Takae Koshiyama、 Makoto Aihara
    • Organizer
      ARVO 2014
    • Place of Presentation
      Orlando, FL, USA
    • Year and Date
      2014-05-03 – 2014-05-08
    • Data Source
      KAKENHI-PROJECT-24659755
  • [Presentation] Association between estrogen receptor and intraocular pressure in mice

    • Author(s)
      Fumihiko Mabuchi, Reiko Yamagishi, Kenji Kashiwagi, Makoto Aihara
    • Organizer
      American Society of Human Genetics (ASHG)
    • Place of Presentation
      Boston Convention and Exhibition Center (Boston)
    • Data Source
      KAKENHI-PROJECT-24592621
  • [Presentation] Characterization of RGC death in Rho-GTPases activating proteins Vav proteins, deficient mice

    • Author(s)
      Keiko Fujikawa、Kaoru Inoue、Reiko Yamagishi、 Takae Koshiyama、 Makoto Aihara
    • Organizer
      ARVO 2015
    • Place of Presentation
      Denver, CO, USA
    • Year and Date
      2015-05-02 – 2015-05-07
    • Data Source
      KAKENHI-PROJECT-24659755
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  鈴木 卓 (30196836)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  藤森 功 (70425453)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  供田 洋 (70164043)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  島本 茂 (00610487)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  秋光 信佳 (40294962)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 38.  伊藤 大知 (50447421)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 39.  SAWAMURA Hiromasa
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  新家 真
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 15 results
  • 41.  田中 理恵
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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