HAISHIMA Yuji 〓島由二

… Alternative Names

はい島由二ハイシマユウジ

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Researcher Number	80228379
Other IDs	https://orcid.org/0009-0000-1781-5554
Affiliation (based on the past Project Information) *help	2005 – 2006: 国立医薬品食品衛生研究所, 療品部, 室長 1999 – 2002: 国立医薬品食品衛生研究所, 療品部, 室長 1999: 日立医療品食品衛生研究所, 療品部, 室長 1997: 国立医薬品食品衛生研究所, 療品部, 室長 1997: National Institute of Health Sciences, Bacteriology, 衛生微生物部, 室長 … More 1996: 国立衛生試験所, 衛生微生物部, 主任研究員 1994 – 1996: 国立衛生試験所, 衛生微生物部, 研究員 1995: National Institute of Health Sciences Microbiology, Researcher, 衛生微生物部, 研究員 Less
Review Section/Research Field	Principal Investigator Bacteriology (including Mycology) / Morphological basic dentistry Except Principal Investigator Morphological basic dentistry / Bacteriology (including Mycology) / Periodontal dentistry / Periodontal dentistry
Keywords	Principal Investigator エンドトキシン / リピドA / リポ多糖 / アンタゴニスト / Porphyromonas gingivalis Except Principal Investigator Porphyromonas gingivalis / rCTB / periodontal disease / fimbria / mucosal vaccination … More / 粘膜免疫 / IgA / 線毛 / Porphyromanas gingivalis / 粘膜ワクチン / 歯周病 / 歯周病ワクチン / C3H / P.gingivalis / synthetic lipid A / antagonist / lipid A / endotoxin / サクシニル化 / 化学合成リピドA / アンタゴニスト / リピドA / エンドトキシン / biological properties / lipopolysaccharide / 化学合成 / 生物活性 / 合成リピドA / 内毒素 / 歯周病モデル動物 / 歯槽骨吸収 / 経鼻投与 / (8)血清型 / (7)莢膜 / rCTBコンジュゲート / (6)LPS / (5)rCTB / (4)LPS / (3)Porphyromonas gingivalis / (2)粘膜免疫 / (1)歯周病ワクチン / 無毒化LPS / リコンビナントコレラトキシンB / 分泌型IgA / 歯周病予防 / LPS / リコンビナントコレラトキシン / プロテアーゼ阻害剤 / ワクチン / 経鼻免疫 / TNF-alpha / HeJ mice / HeJマウス / succinylation Less

Research Projects
(9 results)
Co-Researchers
(9 People)

A drug development study for a periodontal disease : Biological properties of synthetic lipid A of Porphyromonas gingivalis lipopolysaccharide
- Principal Investigator
  
  KUMADA Hidefumi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Kanagawa Dental College
Intranasal immunization of mice with P. gingivalis fimbriae and recombinant cholera toxin B subunit induces strong mucosal and systemic immune responses
- Principal Investigator
  
  KUMADA Hidefumi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Kanagawa Dental College
Prevention and treatment of periodntal disease ; the developments of mucosal vaccination and protease inhibitor
- Principal Investigator
  
  UMEMOTO Toshio
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Kanagawa Dental College
Prevention and treatment of periodontal disease ; the application to basic research and drug development on mucosal vaccination
- Principal Investigator
  
  KUMADA Hidefimi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Kanagawa Dental College
細菌内毒素アンタゴニスト構造体の分子モデリング(II)-アンタゴニスト活性に対するリン酸基の影響-Principal Investigator
- Principal Investigator
  
  はい島由二
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  国立衛生試験所
Elucidation of the chemical factor controlling the antagonistic structure of the lipid A, and mechanism of its suppressive activity
- Principal Investigator
  
  TANAMOTO Ken-ichi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  NATIONA INSTITUTE OF HEALTH SCIENCES
細菌内毒素アンタゴニスト構造体の分子モデリング-光学異性リピドAアナログの化学合成-Principal Investigator
- Principal Investigator
  
  配島由二
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  国立衛生試験所
Porphyromonas gingivalisのリピドAアナログの化学合成Principal Investigator
- Principal Investigator
  
  配島由二
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  国立衛生試験所
Elucidation of the chemical structure possessing antagonistic activity of endotoxin using chemical synthesis
- Principal Investigator
  
  TANAMOTO Kenich
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  National Institute of Health Sciences

1. KUMADA Hidefumi (60120995)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. HAMADA Nobushiro (20247315)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. WATANABE Kiyoko (70148021)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. OZONO Satou (40084785)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. TAKAHASHI Yusuke (20267511)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. TANAMOTO Kenich (60107430)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. ISHIKAWA Eriko (10104340)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. UMEMOTO Toshio (20067036)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. AMANO Shigeru (90167958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HAISHIMA Yuji 〓島 由二

はい島 由二 ハイシマ ユウジ

Research Projects

Co-Researchers

A drug development study for a periodontal disease : Biological properties of synthetic lipid A of Porphyromonas gingivalis lipopolysaccharide

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Intranasal immunization of mice with P. gingivalis fimbriae and recombinant cholera toxin B subunit induces strong mucosal and systemic immune responses

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Prevention and treatment of periodntal disease ; the developments of mucosal vaccination and protease inhibitor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Prevention and treatment of periodontal disease ; the application to basic research and drug development on mucosal vaccination

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

細菌内毒素アンタゴニスト構造体の分子モデリング(II)-アンタゴニスト活性に対するリン酸基の影響-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the chemical factor controlling the antagonistic structure of the lipid A, and mechanism of its suppressive activity

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

細菌内毒素アンタゴニスト構造体の分子モデリング-光学異性リピドAアナログの化学合成-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Porphyromonas gingivalisのリピドAアナログの化学合成Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the chemical structure possessing antagonistic activity of endotoxin using chemical synthesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

HAISHIMA Yuji 〓島由二

はい島由二ハイシマユウジ