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NAGAMATSU Shinya  永松 信哉

ORCIDConnect your ORCID iD *help
… Alternative Names

永松 信哉  ナガマツ シンヤ

永松 信也  ナカ゛マツ シンヤ

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Researcher Number 80231489
Other IDs
External Links
Affiliation (Current) 2025: 杏林大学, 医学部, 特任教授
Affiliation (based on the past Project Information) *help 2017: 杏林大学, 医学部, 教授
2000 – 2013: 杏林大学, 医学部, 教授
1996 – 1999: 杏林大学, 医学部, 助教授
1995: 杏林大学, 医学部・第II生化学, 助教授
1991 – 1994: 杏林大学, 医学部, 助教授
1992: 杏林大学, 医学部・第2生化学, 助教授
Review Section/Research Field
Principal Investigator
Pathological medical chemistry / Pathological medical chemistry / Cerebral neurosurgery / Metabolomics
Except Principal Investigator
Pathological medical chemistry / Metabolomics / Cerebral neurosurgery / Biological Sciences / Ophthalmology / Pathological medical chemistry … More / Digestive surgery / Metabolomics / Neurochemistry/Neuropharmacology / 内分泌・代謝学 / Cell biology Less
Keywords
Principal Investigator
インスリン分泌 / インスリン / Exocytosis / SNARE / TIRF / 糖尿病 / GFP / diabetes mellitus / Insulin / Fusion … More / 膵β細胞 / Diabetes Medllirus / SNAP / Syntaxin / PCR / 開口放出 / 1分子イメージング / cDNAクローニング / 糖輸送担体 / insulin secretion / pancreatic β cell / imaging / exocytosis / TIRFM / secretory granule / evanescent / confocal microscoov / Ca^<2+> / fusion / 分泌顆粒 / エヴァネッセント / 共焦点レーザー顕微鏡 / Pancreatic beta cell / 膵β細部 / 構成性分泌機構 / 調節性分泌機構 / NSF / Pancreatic βcell / Pancreatic β cell / Northern blot / cDNA cloning / GLUT / glucose transporter / Brain tumor / 能腫瘍 / Northern解析 / 脳腫瘍 / 糖代謝異常 / エネルギー / アデノウィルス / アデノウイルス / GLUT4 / 再生医療 / 脂肪細胞 / RT-PCR / Hagfish … More
Except Principal Investigator
インスリン分泌 / 膵β細胞 / 糖尿病 / 開口放出 / PPARγ / GLUT2 / 2型糖尿病 / インスリン / エバネッセント顕微鏡 / exocytosis / 酸化ストレス / シグナル伝達 / 細胞・組織 / 糖輸送担体 / UCP-2 / db / secretory granule / type 2 diaetes / pancreatic beta cell / insulin / 分泌顆粒 / insulin secretion / グルカゴン分泌 / RACK1 / GLUT3 / GLUT1 / ATP感受性K^+チャネル / C-CAM / cell-cell adhesion molecules / glucose transporter / 細胞細胞接着蛋白質 / 細胞-細胞接着蛋白質 / Histone / MCP-1 / 脂肪細胞 / マクロファージ / TIRFM / ラット / 網膜 / 開口分泌 / 妊娠 / 妊娠糖尿病 / TIRF microscopy / insulin resistance / db mouse / type 2 diabetes / oxidative stress / pancreatic βcell / MIN6細胞 / グルタミン酸 / チアゾリジン誘導体 / インスリン抵抗性 / dbマウス / evanescentwave microscopy / 1分子イメージング / Endocrine function / Acute pancreatitis / インスリン分泌脳 / 免疫組織化学 / インスリン分泌能 / 内分泌機能 / 内分泌動態 / 急性膵炎 / insulin biosynthesis / exocytotic system / glucagon secretion / intracellular calcium / free fatty acids / proinsulin / カルシウムイオン / インスリン生合成 / 分泌顆粒放出系 / 細胞内カルシウム濃度 / 遊離脂肪酸 / プロインスリン / F-actin / chromaffin / protein kinase C / プロテインキナーゼ C / F-アクチン / クロマフィン細胞 / プロテインキナーゼC / 伝達物質放出 / glucose metabolism / rat / retina / 糖輸送坦体 / グルコース代謝 / voltage-dependent calcium channel / ATP-sensitive KィイD1+ィエD1 channel / cyclic AMP / calmodulin / SNARE protcins / intraccllular calcium / insulin secrction / diabetes mellitus / パッチクランプ法 / 細胞内Ca^<2+>濃度 / ブドウ糖 / 電位依存性CA^<2+>チャネル / バッチクランプ法 / 細胞内情報伝達系 / 電位依存性Ca^<2+>チャネル / 電位依存性Ca_<2+>チャネル / サイクリックAMP / カルモジュリン / SNARE蛋白群 / 細胞内カルシウム / blood barrier / K3 protein / グリオ-マ細胞 / CーCAM105 / 脳血液関門 / K3 / nucleolin / suppressor gene P-53 / brain tumor / cell kinetics / ガン抑制遺伝子 / 細胞細胞接着蛋白 / 成長因子 / がん抑制遺伝子 / モノクロ-ナル抗体 / MIB-1 / ヌクレオリン / 癌抑制遺伝子 / 脳腫瘍 / 成長解析 / CDKAL1 / GWAS / アンカップリング / VEGF / 熱ショック蛋白 / サイトカイン / 膵ラ氏島 / 細胞内トラフィック / 全反射顕微鏡 / 細胞内輸送 / Glucose Transporter / Development / Glucase Transpoter / Retina / 発生 / グルコース Less
  • Research Projects

    (25 results)
  • Research Products

    (305 results)
  • Co-Researchers

    (30 People)
  •  Mechanisms of increased glucose-stimulated insulin secretion during pregnancy

    • Principal Investigator
      Ohara-Imaizumi Mica
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kyorin University
  •  Deletion of CDKAL1 affects first-phase glucose stimulated insulin exocytosis

    • Principal Investigator
      OHARA-IMAIZUMI Mica
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kyorin University
  •  Elucidation of involved mechanisms for macrophage infiltration into pancreatic islets and of its role on the occurrence of type 2 diabetes.

    • Principal Investigator
      ISHIDA Hitoshi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kyorin University
  •  Imaging analysis of impaired insulin exocytosis in type2 diabetes mellitusPrincipal Investigator

    • Principal Investigator
      NAGAMATSU Shinya
    • Project Period (FY)
      2008 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Metabolomics
    • Research Institution
      Kyorin University
  •  Mechanisms of biphasic insulin granule exocytosis by imaging technique

    • Principal Investigator
      MICA Ohara-Imaizumi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      Kyorin University
  •  Elucidation of involved mechanisms impaired for insulin secretion due to oxidative stress and macrophages in pancreatic islets of type 2 diabetes.

    • Principal Investigator
      ISHIDA Hitoshi
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kyorin University
  •  インスリン分泌顆粒細胞内トラフィックのVTIRF解析

    • Principal Investigator
      今泉 美佳
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyorin University
  •  Imaging analysis reveals mechanistic differences between first and second phase insulin exocytosis

    • Principal Investigator
      IMAIZUMI Mika
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kyorin University
  •  インスリン分必顆粒輸送の可視化解析-貯蔵からFusionまで-

    • Principal Investigator
      今泉 美佳
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyorin University
  •  Study of impaired insulin exocytosis in diabetes mellitus by imaging techniquePrincipal Investigator

    • Principal Investigator
      NAGAMATSU Shinya
    • Project Period (FY)
      2003 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kyorin University
  •  New strategy for treatment of type 2 diabetes by utilizing the regeneration of pancreatic β cell function

    • Principal Investigator
      ISHIDA Hitoshi
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kyorin University
  •  脂肪細胞を利用したインスリン分泌機構の再構成Principal Investigator

    • Principal Investigator
      永松 信哉
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kyorin University
  •  Mechanism of insulin exocytosis in pancreatic β cells by analyzing single insulin granule motion with evanescent wave microscopy

    • Principal Investigator
      OHARA Mica
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kyorin University
  •  Molecular physiological and biological studies on the effect of free fatty acids on pancreatic β cell function

    • Principal Investigator
      ISHIDA Hitoshi, 古川 尚志
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      Kyorin University
  •  Analysis of pancreatic endocrine function in acute pancreatitis

    • Principal Investigator
      ABE Nobutsugu, SASAKI Hideo, 泉里 友文
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyorin University
  •  Elucidation of the mechanism of impaired insulin release in diabetes mellitus by the molecular cell biological techniquesPrincipal Investigator

    • Principal Investigator
      NAGAMATSU Shinya
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kyorin University
  •  Analysis of the Functional Role of Glucose Trans porter in Glucose Homeostasis in the Retina

    • Principal Investigator
      WATANABE Takashi
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Kyorin University
  •  Role of activated protein kinase C in the mechanism for MgATP-dependent Priming of exocytosis in adrenal chromaffin cells

    • Principal Investigator
      OHARA Mica
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kyorin University
      Sophia University
  •  Molecular physiological and biological studies on the mechanismof impaired glucose-induced insulin secretion in diabetes mellitus

    • Principal Investigator
      ISHIDA Hitoshi
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      内分泌・代謝学
    • Research Institution
      Kyorin University
      Kyoto University
  •  Study of the molecular mechanism of insulin exocytosis by SNARE hypothesisPrincipal Investigator

    • Principal Investigator
      NAGAMATSU Shinya
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Kyorin University school of Medicine
  •  網膜における糖輸送担体の機能及び発現制御機構に関する分子生物学的研究

    • Principal Investigator
      WATANABE Takashi (渡邉 卓)
    • Project Period (FY)
      1995 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      Kyorin University
  •  糖輸送担体スーパーファミリーの分子進化Principal Investigator

    • Principal Investigator
      永松 信哉
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyorin University
  •  Molecular Biology of Glucose Transporter expressed in Brain TumorsPrincipal Investigator

    • Principal Investigator
      NAGAMATSU Shinya
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kyorin Univ.
  •  Cell and molecular bilogical study of novel cell-cell adhesion molecules.

    • Principal Investigator
      SAWA Hiroki
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kyorin University
  •  Quantitation and investigation of malignancy of brain tumors

    • Principal Investigator
      TAKEUCHI Kazuo, HOSHINO Takao
    • Project Period (FY)
      1990 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Cerebral neurosurgery
    • Research Institution
      Kyorin University

All 2017 2016 2015 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 2003 2002 Other

All Journal Article Presentation Book

  • [Book] Imaging of insulin exocytosis from pancreatic beta cells. Exocytosis Methods. Neuromethods 83. Springer Protocols. Thorn P. (ed.)2013

    • Author(s)
      Ohara-Imaizumi M, Aoyagi K, Nagamatsu S
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Book] Exocytosis Methods. (Neuromethods 83. Springer Protocols. )2013

    • Author(s)
      Ohara-Imaizumi M, Aoyagi K, Nagamatsu S.
    • Total Pages
      248
    • Publisher
      Humana Press.
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Book] 糖尿病・代謝・内分泌2011

    • Author(s)
      永松信哉
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Book] 糖尿病ナビゲーター 第2版2010

    • Author(s)
      青柳共太、永松信哉
    • Total Pages
      2
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Book] 臨床神経学2009

    • Author(s)
      江口博人, 今泉美佳・永松信哉, その他7名
    • Total Pages
      1
    • Publisher
      日本神経学会
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Book] インスリン顆粒の細胞内trafficking(ss細胞研究の最前線)糖尿病学の進歩20092009

    • Author(s)
      今泉美佳, 永松信哉
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Book] 糖尿病学の進歩2009

    • Author(s)
      今泉美佳・永松信哉
    • Total Pages
      5
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Book] 糖尿病学の進歩2009

    • Author(s)
      今泉美佳・永松信哉
    • Total Pages
      5
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Book] (杏林大・医・生化学):インスリン顆粒の細胞内 trafficking (β細胞研究の最前線)糖尿病学の進歩(日本糖尿病学会編)(東京)2009

    • Author(s)
      今泉美佳, 永松信哉
    • Publisher
      診断と治療社
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Book] 糖尿病学の進歩2009((社)日本糖尿病学会編)(診断と治療社 インスリン顆粒の細胞内trafficking(β細胞研究の最前線))2009

    • Author(s)
      今泉美佳,永松信哉
    • Publisher
      杏林大・医・生化学
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Book] Imaging Exocytosis of Single Insulin Secretory Granules With TIRF Microscopy.4402008

    • Author(s)
      Nagamatsu S, Ohara-Imaizumi M.
    • Publisher
      Methods in Mol Biol
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Book] Diabetes Journal2008

    • Author(s)
      青柳共太&永松信哉
    • Total Pages
      11
    • Publisher
      インスリン分泌機構-エバネツセント顕微鏡で見えるもの
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Book] Diabetes Tournal2008

    • Author(s)
      青柳共太&永松信哉
    • Total Pages
      11
    • Publisher
      インスリン分泌機構-エバネッセント顕微鏡で見えるもの
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Book] インスリン分泌機構-エバネッセント顕微鏡で見えるもの2008

    • Author(s)
      青柳共太, 永松信哉
    • Publisher
      Diabetes J.36
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Book] Mechanism of insulin exocytosis analyzed by imaging techniques. Pancreatic beta cell in health and disease(eds ; Seino S. and G. I. Bell) Japan2008

    • Author(s)
      Nagamatsu S and Ohara-Imaizumi M.
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Book] Pancreatic beta cell in health and disease(eds ; Seino S.and G.I.Bell)(Mechanism of insulin exocytosis analyzed by imaging techniques.)2008

    • Author(s)
      永松信哉,今泉美佳
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Book] Mechanism of insulin exocvtosis analyzed by imaging techniques, in Pancreatic Beta Cell in Health and Disease2007

    • Author(s)
      Nagamatsu S., Ohara-Imaizumi M.
    • Total Pages
      17
    • Publisher
      Springer Verlag, Berlin Germany
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Book] Mechanism of insulia exocytosis analyzed by imaging techniques. in Pancreatic Beta CeU in Health and Disease2007

    • Author(s)
      Nagamatsu S., Ohara-Imaizumi M..
    • Total Pages
      17
    • Publisher
      Springer Verlag, Berlin Germany,
    • Data Source
      KAKENHI-PROJECT-18050033
  • [Book] Mechanism of insulin exocytosis analyzed by imaging techniques.in Pancreatic Beta Cell in Health and Disease2007

    • Author(s)
      Nagamatsu S., Ohara-Imaizumi M.
    • Total Pages
      17
    • Publisher
      Springer Verlag, Berlin Germany
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Book] 分子糖尿病学の進歩 基礎から臨床まで20062006

    • Author(s)
      今泉 美佳, 永松 信哉
    • Publisher
      金原出版(In press)
    • Data Source
      KAKENHI-PROJECT-16044240
  • [Book] 分子糖尿病学の進歩 基礎から臨床まで20062006

    • Author(s)
      今泉 美佳, 永松 信哉
    • Publisher
      金原出版(In press)
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Book] インスリン顆粒開口放出とその異常 分子糖尿病学の進歩 -基礎から臨床まで-20062006

    • Author(s)
      今泉美佳, 永松信哉
    • Total Pages
      10
    • Publisher
      金原出版
    • Data Source
      KAKENHI-PROJECT-18050033
  • [Book] 分子糖尿病学の進歩 基礎から臨床まで20062006

    • Author(s)
      今泉 美佳, 永松 信哉
    • Publisher
      金原出版(In press)
    • Data Source
      KAKENHI-PROJECT-15390108
  • [Book] インスリン穎粒開口放出とその異常 分子糖尿病学の進歩 -基礎から臨床まで-2006,2006

    • Author(s)
      今泉美佳, 永松信哉.
    • Total Pages
      10
    • Publisher
      金原出版
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Book] 糖尿病カレントライブラリー2004

    • Author(s)
      永松信哉
    • Total Pages
      6
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-15390108
  • [Book] Recent research development in biophysics & biochemistry2003

    • Author(s)
      Nagamatsu S, Ohara-Imaizumi M
    • Publisher
      SNARE-mediated insulin exocytosis.
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Book] インスリン分泌の可視化.糖尿病・代謝・内分泌

    • Author(s)
      永松信哉
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Book] (1杏林大・医・生化学)インスリン分泌における開口放出機構糖尿病ナビゲーター第2版(東京)

    • Author(s)
      青柳共太、永松信哉
    • Publisher
      メディカルレビュー社
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] VAMP7 regulates autophagy to maintain mitochondrial homeostasis and to control insulin secretion in pancreatic beta-cells.2016

    • Author(s)
      Aoyagi K, Ohara-Imaizumi M, Itakura M, Torii S, Akimoto Y, Nishiwaki C, Nakamichi Y, Kishimoto T, Kawakami H, Harada A, Takahashi M, Nagamatsu S
    • Journal Title

      Diabetes

      Volume: 65 Issue: 6 Pages: 1648-1659

    • DOI

      10.2337/db15-1207

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K19525, KAKENHI-PUBLICLY-15H00901, KAKENHI-PROJECT-26460396
  • [Journal Article] Opposing roles for SNAP23 in secretion in exocrine and endocrine pancreatic cells2016

    • Author(s)
      Masataka Kunii, et al,
    • Journal Title

      J. Cell Biol.

      Volume: 215 Issue: 1 Pages: 121-138

    • DOI

      10.1083/jcb.201604030

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-15H05953, KAKENHI-PLANNED-26110003, KAKENHI-PROJECT-26221001, KAKENHI-PROJECT-26242082, KAKENHI-PROJECT-15H04668, KAKENHI-PROJECT-26291036, KAKENHI-PROJECT-26350976, KAKENHI-PROJECT-26460290, KAKENHI-PROJECT-15K19525, KAKENHI-PROJECT-16K08519, KAKENHI-PROJECT-26460396
  • [Journal Article] Serotonin regulates glucose stimulated insulin secretion from pancreatic β cells during pregnancy.2013

    • Author(s)
      Ohara-Imaizumi, M., Kim, H., Yoshida, M., Fujiwara, T., Aoyagi, K., Toyofuku, Y., Nakamichi, Y., Nishiwaki, C., Okamura, T., Uchida, T., Fujitani, Y., Akagawa, K., Kakei, M., Watada, H., German, M.S., and Nagamatsu, S.
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 110 Pages: 19420-19425

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Journal Article] Serotonin regulates glucose-stimulated insulin secretion from pancreatic ß cells during pregnancy.2013

    • Author(s)
      Ohara-Imaizumi, M., Kim, H., Yoshida, M., Fujiwara, T., Aoyagi, K., Toyofuku, Y., Nakamichi, Y., Nishiwaki, C., Okamura, T., Uchida, T., Fujitani, Y., Akagawa, K., Kakei, M., Watada, H., German, M.S., and Nagamatsu, S.
    • Journal Title

      Proc. Natl. Acad. Sci. USA

      Volume: 110 Issue: 48 Pages: 19420-19425

    • DOI

      10.1073/pnas.1310953110

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500508, KAKENHI-PROJECT-23590369, KAKENHI-PROJECT-25860756
  • [Journal Article] Insulin homeostasis through zinc-mediated pancreas-to-liver metabolic communication.2013

    • Author(s)
      Tamaki, M., Fujitani, Y, Uchida, T., Tamura, Y., Takeno, K., Kawaguchi, M., Watanabe, T., Hara, A., Ogihara, T., Shimizu, T., Mita, T., Hirose, T., Ohara-Imaizumi, M., Abe, T., Kiyonari, H., Hojyo, S., Fukada, T., Nagamatsu, S., Hirano, T., Kawamori, R., Watada, H.
    • Journal Title

      J Clin Invest.

      Volume: 123 Pages: 4513-4524

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Journal Article] The diabetes-susceptible gene SLC30A8/ZnT8 regulates hepatic insulin clearance2013

    • Author(s)
      Tamaki, M., Fujitani, Y, Uchida, T., Tamura, Y., Takeno, K., Kawaguchi, M., Watanabe, T., Hara, A., Ogihara, T., Shimizu, T., Mita, T., Hirose, T., Ohara-Imaizumi, M., Abe, T., Kiyonari, H., Hojyo, S., Fukada, T., Nagamatsu, S., Hirano, T., Kawamori, R., Watada, H.
    • Journal Title

      J Clin Invest

      Volume: 123 Issue: 10 Pages: 4513-4524

    • DOI

      10.1172/jci68807

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590369, KAKENHI-PROJECT-23592239, KAKENHI-PROJECT-24790933, KAKENHI-PROJECT-24790936, KAKENHI-PROJECT-25461364, KAKENHI-PROJECT-25860371, KAKENHI-PROJECT-25860757
  • [Journal Article] Acute inhibition of PI3K-PDK1-Akt pathway potentiates insulin secretion through upregulation of newcomer granule fusions in pancreatic beta-cells.2012

    • Author(s)
      Aoyagi K, Ohara-Imaizumi M, Nishiwaki C, Nakamichi Y, Ueki K, Kadowaki T and Nagamatsu, S.
    • Journal Title

      PLoS One.

      Volume: 7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Journal Article] Acute inhibition of PI3K-PDK1-Akt pathway potentiates insulin secretion through upregulation of newcomer granule fusions in pancreatic beta-cells2012

    • Author(s)
      Aoyagi, K., Ohara-Imaizumi, M., Nishiwaki, C., Nakamichi, Y., Ueki, K., Kadowaki, T. and Nagamatsu, S.
    • Journal Title

      PLoS One

      Volume: 7 Issue: 10 Pages: e47381-e47381

    • DOI

      10.1371/journal.pone.0047381

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Journal Article] DPP-4 inhibitor des-F-sitagliptin treatment increased insulin exocytosis from db/db mice β cells2011

    • Author(s)
      Shinya Nagamatsu, 他4名
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 412 Pages: 556-560

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] DPP-4 inhibitor des-F-sitagliptin treatment increased insulin exocytosis from db/db mice β cells.2011

    • Author(s)
      Nagamatsu S., Ohara-Imaizumi M.(他3名)
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 412 Pages: 556-560

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Journal Article] DPP-4 inhibitor des-F-sitagliptin treatment increased insulin exocytosis from db/db mice beta cells2011

    • Author(s)
      Nagamatsu, S., Ohara-Imaizumi, M., Nakamichi, Y., Aoyagi, K. and Nishiwaki, C.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 412 Issue: 4 Pages: 556-560

    • DOI

      10.1016/j.bbrc.2011.07.119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Journal Article] The pathomechanisms of young-onset Parkinson's disease(PD), approach to the causes of PD form the mechanisms of insulin secretion system2011

    • Author(s)
      Hattori N, Eguchi H, Imaizumi M, Saiki S, Sato S, Nagamatsu S
    • Journal Title

      Rinsho Shinkeigaku

      Volume: 51(11) Pages: 986-7

    • NAID

      130004504947

    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Regulation of resident and newcomer insulin granules by calcium and SNARE proteins2011

    • Author(s)
      Aoyagi, K., Ohara-Imaizumi, M., Nagamatsu, S.
    • Journal Title

      Front Biosci

      Volume: 16 Pages: 1197-1210

    • URL

      http://www.bioscience.org/2011/V16/af/3784/fulltext.htm

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Journal Article] 若年性パーキンソン病の病態解明:インスリン開口機構からその病因に迫る2011

    • Author(s)
      服部信孝, 永松信哉, 他4名
    • Journal Title

      臨床神経

      Volume: 51 Pages: 986-987

    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Regulation of resident and newcomer insulin granules by calcium and SNARE proteins.2011

    • Author(s)
      Aoyagi K, Ohara-Imaizumi M, Nagamatsu S.
    • Journal Title

      Front Biosci.Jan 1

      Volume: 16 Pages: 1197-210

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] DPP-4 inhibitor des-F-sitagliptin treatment increased insulin exocytosis from db/db mice ss cells2011

    • Author(s)
      Nagamatsu S, Ohara-Imaizumi M, Nakamichi Y, Aoyagi K, Nishiwaki C
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 412(4) Pages: 556-60

    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Regulation of resident and newcomer insulin granules by calcium and SNARE proteins.2011

    • Author(s)
      Aoyagi K, Ohara-Imaizumi M, Nagamatsu S
    • Journal Title

      Front Biosci. 16

      Pages: 1197-210

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Journal Article] Regulation of resident and newcomer insulin granules by calcium and SNARE proteins2011

    • Author(s)
      Aoyagi K, Ohara-Imaizumi M, Nagamatsu S
    • Journal Title

      Front Biosci

      Volume: 16 Pages: 1197-210

    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan,2010

    • Author(s)
      Ohara-Imaizumi M. , Yoshida M. Aoyagi K, Saito T, Okamura T, Takenaka H, AkimotoY, Nakamichi, Takanashi-Yanobu R, Nishiwaki C, Kawakami H, Kato N, Hisanaga S, Kakei M, Nagamatsu S
    • Journal Title

      Deletion of CDKAL1 Affects First-phase Glucose-stimulated Insulin Exocytosis PLoS ONE 5, e15553

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Regulation of resident and newcomer insulin granules by calcium and SNARE proteins.2010

    • Author(s)
      Aoyagi K, Ohara-Imaizumi M, Nagamatsu S.
    • Journal Title

      Front Biosci.

      Volume: 16 Pages: 1197-1210

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Journal Article] Deletion of CDKAL1 Affects First-phase Glucose-stimulated Insulin Exocytosis2010

    • Author(s)
      Ohara-Imaizumi M., Aoyagi K., Nagamatsu S, (他12名)
    • Journal Title

      PLoS ONE

      Volume: 5:e15553

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Journal Article] Deletion of CDKAL1 Affects First-phase Glucose-stimulated Insulin Exocytosis2010

    • Author(s)
      Ohara-Imaizumi M., Nagamatsu S, (他13名)
    • Journal Title

      PLoS ONE

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Gαo represses insulin secretion by reducing vesicular docking in pancreatic β cells2010

    • Author(s)
      Zhao A, Ohara-Imaizumi M, Brissova M, Benninger RK, Xu Y, Hao Y, Abramowitz J, Boulay G, Powers A C, Piston D, Jiang M, Nagamatsu S, Birnbaumer L, Gu G
    • Journal Title

      Diabetes 59

      Pages: 2522-2529

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Journal Article] Deletion of CDKAL1 Affects First-phase Glucose-stimulated Insulin Exocytosis2010

    • Author(s)
      Ohara-Imaizumi M., Yoshida M. Aoyagi K, Saito T, Okamura T, Takenaka H, Akimoto Y, Nakamichi Y, Takanashi-Yanobu R, Nishiwaki C, Kawakami H, Kato N, Hisanaga S, Kakei M, and Nagamatsu S.
    • Journal Title

      PLoS One

      Volume: 5

    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] G・o represses insulin secretion by reducing vesicular docking in pancreatic ss cells2010

    • Author(s)
      Zhao A, Ohara-Imaizumi M, Brissova M, Benninger RK, Xu Y, Hao Y, Abramowitz J, Boulay G, Powers A C, Piston D, Jiang M, Nagamatsu S, Birnbaumer L and Gu G.
    • Journal Title

      Diabetes

      Volume: 59 Pages: 2522-2529

    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Insulin/phosphatidylinositol 3-kinase pathway accelerates the glucose-induced first phase insulin secretion through TrpV2 recruitment in pancreatic beta-cells2010

    • Author(s)
      Aoyagi K, Ohara-Imaizumi M, Nagamatsu S, (他2名)
    • Journal Title

      Biochem J.

      Volume: 432 Pages: 375-386

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Journal Article] Deletion of CDKAL1 Affects First-phase Glucose-stimulated Insulin Exocytosis2010

    • Author(s)
      Ohara-Imaizumi M., Yoshida M.Aoyagi K, Saito T, Okamura T, Takenaka H, Akimoto Y, Nakamichi Y, Takanashi-Yanobu R, Nishiwaki C, Kawakami H, Kato N, Hisanaga S, Kakei M, Nagamatsu S
    • Journal Title

      PLoS One 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Journal Article] Insulin/phosphatidylinositol 3-kinase pathway accelerates the glucose-induced first phase insulin secretion through TrpV2 recruitment in pancreatic beta-cells.2010

    • Author(s)
      Aoyagi K, Ohara-Imaizumi M, Nishiwaki C, Nakamichi Y, Nagamatsu S
    • Journal Title

      Biochem J. 432

      Pages: 375-386

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Journal Article] Insulin/phosphatidylinositol 3-kinase pathway accelerates the glucose-induced first phase insulin secretion through TrpV2 recruitment in pancreatic beta-cells2010

    • Author(s)
      Aoyagi K, Ohara-Imaizumi M, Nishiwaki C, Nakamichi Y, Nagamatsu S.
    • Journal Title

      Biochem J

      Volume: 432 Pages: 375-386

    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Pattern of rise in subplasma membrane Ca2+ concentration determines type of fusing insulin granules in pancreatic beta cells.2009

    • Author(s)
      Ohara-Imaizumi M, Aoyagi K, Nakamichi Y, Nishiwaki C, Sakurai T, Nagamatsu S.
    • Journal Title

      Biochem Biophys Res Commun.Jul 31;385(3)

      Pages: 192-195

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Pattern of rise in subplasma membrane Ca2+concentration determines type of fusing insulin granules in pancreatic <beta> cells2009

    • Author(s)
      Ohara-Imaizumi M, NagamatsuS., (他4名)
    • Journal Title

      Biochemical and Biophysical Research Communications (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] but not sulfonylurea, can evoke insulin exocytosis by repetitive stimulation : imaging analysis of insulin exocytosis by secretagogue-induced repetitive stimulations.2009

    • Author(s)
      Aoyagi K, Ohara-Imaizumi M, Nishiwaki C, Nakamichi Y, Nagamatsu S. Glinide
    • Journal Title

      Exp Diabetes Res. 2009

      Pages: 278762-278762

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Journal Article] Imaging exocytosis of single glucagon-like peptide-1 containing granules in a murine enteroendocrine cell line with total internal reflection fluorescent microscopy.2009

    • Author(s)
      Ohara-Imaizumi M, Aoyagi K, Akimoto Y, Nakamichi Y, Nishiwaki C, Kawakami H2, Nagamatsu S
    • Journal Title

      Biochem Biophys Res Commun. 390

      Pages: 16-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Journal Article] Imaging exocytosis of single glucagon-like peptide-1 containing granules in amurine enteroendocrine cell line with total internal reflection fluorescent microscopy.2009

    • Author(s)
      Ohara-Imaizumi M, Nagamatsu S., その他4名
    • Journal Title

      Biochem Biophys Res Commun. 391

      Pages: 16-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Journal Article] Glinide but not sulfonylurea, can evoke insulin exocytosis by repetitive stimulation : imaging analysis of insulin exocytosis by secretagogue-induced repetitive stimulations2009

    • Author(s)
      Aoyagi K, Ohara-Imaizumi M, Nishiwaki C, Nakamichi Y, Nagamatsu S. Glinide
    • Journal Title

      Exp Diabetes Res

      Volume: 2009 Pages: 278762-278762

    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Pattern of rise in subplasma membrane Ca2+ concentration determines type of fusing insulin granules in pancreatic beta cells.2009

    • Author(s)
      Ohara-Imaizumi M, Aoyagi K, Nakamichi Y, Nishiwaki C, Sakurai T2, Nagamatsu S
    • Journal Title

      Biochem Biophys Res Commun. 385

      Pages: 291-295

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Journal Article] Pattern of rise in subplasma membrane Ca2+ concentration determines type of fusing insulin granules in pancreatic beta cells.2009

    • Author(s)
      Ohara-Imaizumi M, Nagamatsu S., その他4名
    • Journal Title

      Biochem Biophys Res Commun. 385

      Pages: 291-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Pattern of rise in subplasma membrane Ca2+ concentration determines type of fusing insulin granules in pancreatic <beta> cells2009

    • Author(s)
      Ohara-Imaizumi M, Nagamatsu S., (他4名)
    • Journal Title

      Biochemical and Biophysical Research Communications (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Journal Article] Imaging exocytosis of single glucagon-like peptide-1 containing granules in a murine enteroendocrine cell line with total internal reflection fluorescent microscopy2009

    • Author(s)
      Ohara-Imaizumi M, Aoyagi K, Akimoto Y, Nakamichi Y, Nishiwaki C, Kawakami H2, Nagamatsu S.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 390 Pages: 16-20

    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Imaging exocytosis of single glucagon-like peptide-1 containing granules in a murine enteroendocrine cell line with total internal reflection fluorescent microscopy.2009

    • Author(s)
      Ohara-Imaizumi M, Aoyagi K, Akimoto Y, Nakamichi Y, Nishiwaki C, Kawakami H, Nagamatsu S
    • Journal Title

      Biochem Biophys Res Commun 4;390(1)

      Pages: 16-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Imaging exocytosis of single glucagon-like peptide-1 containing granules in a murine enteroendocrine cell line with total internal reflection fluorescent microscopy.2009

    • Author(s)
      Ohara-Imaizumi M, Nagamatsu S., その他4名
    • Journal Title

      Biochem Biophys Res Commun. 391

      Pages: 16-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Glinide, but not sulfonylurea, can evoke insulin exocytosis by repetitive stimulation : imaging analysis of insulin exocytosis by secretagogue-induced renetitive stimulations.2009

    • Author(s)
      Aoyagi K, Ohara-Imaizumi M, Nagamatsu S., その他2名
    • Journal Title

      Exp Diabetes Res. 2009

      Pages: 278762-278762

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Journal Article] Pattern of rise in subplasma membrane Ca2+ concentration determines type of fusing insulin granules in pancreatic beta cells.2009

    • Author(s)
      Ohara-Imaizumi M, Nagamatsu S., その他4名
    • Journal Title

      Biochem Biophys Res Commun. 385

      Pages: 291-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Journal Article] Glinide, but not sulfonylurea, can evoke insulin exocytosis by repetitive stimulation : imaging analysis of insulin exocytosis by secretagogue-induced repetitive stimulations.2009

    • Author(s)
      Aoyagi K, Ohara-Imaizumi M, Nagamatsu S., その他2名
    • Journal Title

      Exp Diabetes Res. 2009

      Pages: 278762-278762

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Imaging Exocytosis of Single Insulin Secretory Granules With TIRF Microscopy.2008

    • Author(s)
      Nagamatsu S & Ohara-Imaizumi
    • Journal Title

      . Methods MolBiol 440

      Pages: 259-268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Journal Article] Imaging of insulin exocytosis in GK rat beta cells subjected t0 long-term glinide or sulphonylureatreatment2008

    • Author(s)
      Kawai J.、 Ohara-Imaizuini M.Nagamatsu S. (他9名)
    • Journal Title

      Biochem、J. 412

      Pages: 93-101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18050033
  • [Journal Article] Adiponectin induces insulin secretion in vitro and in vivo at a low glucose concentration2008

    • Author(s)
      Okamoto M, Ohara-Imaizumi M, Kubota N, Hashimoto S, Eto K, Kanno T, Kubota T, Wakui M, Nagai R, Noda M, Nagamatsu S & Kadowaki T
    • Journal Title

      Diabetologia

      Volume: 51 Pages: 827-835

    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Insulin exocytosis in Goto-Kakizaki rat beta-cells subjected to long-term glinide or sulfonylurea treatment.2008

    • Author(s)
      Kawai J, Ohara-Imaizumi M, Nakamichi Y, Okamura T, Akimoto Y, Matsushima S, Aoyagi K, Kawakami H, Watanabe T, Watada H, Kawamori R, Nagamatsu S
    • Journal Title

      Biochem J 412

      Pages: 93-101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Journal Article] Imaging of insulin exocytosis in GK rat beta cells subjected to long-term glinide or sulphonylurea treatment2008

    • Author(s)
      Kawai J., Ohara-Imaizumi M., Nagamatsu S.(他9名)
    • Journal Title

      Biochem.J. 412

      Pages: 93-101

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Adiponectin induces insulin secretion in vitro and in vivo at a low glucose concentration.2008

    • Author(s)
      Okamoto M, Ohara-Imaizumi M, Nagamatsu S., (他9名)
    • Journal Title

      . Diabetologia 51

      Pages: 93-101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Journal Article] Imaging of insulin exocytosis in GK rat beta cells subjected to long-term glinide or sulphonylurea treatment2008

    • Author(s)
      Kawai, J., Ohara-Imaizumi, M., Nakamichi, Y., Okamura, T., Akimoto, Y., Matsushima, S., Aovagi, K., Kawakami, H., Watanabe, T., Watada, H., Kawamori, R., Nagamatsu, S
    • Journal Title

      Biochem. J 412

      Pages: 93-101

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Insulin exocytosis in Goto-Kakizaki rat beta-cells subjected to long-term glinide or sulfonylurea treatment2008

    • Author(s)
      Kawai J, Ohara-Imaizumi M, Nakamichi Y, Okamura T, Akimoto Y, Matsushima S, Aoyagi K, Kawakami H, Watanabe T, Watada H, Kawamori R & Nagamatsu S.
    • Journal Title

      Biochem J

      Volume: 412 Pages: 93-101

    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Adiponectin induces insulin secretion in vitro and in vivo at a low glucose concentration.2008

    • Author(s)
      Okamoto M, Ohara-Imaizumi M, & Nagamatsu S., (他9名)
    • Journal Title

      Diabetologia 51

      Pages: 93-101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Imaging Exocytosis of Single Insulin Secretory Granules With TIRF Microscopy2008

    • Author(s)
      Nagamatsu S & Ohara-Imaizumi M.
    • Journal Title

      Methods in Mol Biol

      Volume: 440 Pages: 259-268

    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Adiponectin induces insulin secretion in vitro and in vivo at a low glucose concentration.2008

    • Author(s)
      Okamoto M Ohara-Imaizumi M Nagamatsu S.(他9名)
    • Journal Title

      Diabetologia 51

      Pages: 827-835

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] JNK-and IκB-dependent pathways regulate MCP-1, but not adiponectin, release from artificially hypertrophied 3T3-L1 adipocytes preloaded with palmitate in vitro.2008

    • Author(s)
      K. Takahashi, S. Yamaguchi, T. Shimoyama, H. Seki, K. Miyokawa, H. Katsuta, T. Tanaka, K. Yoshimoto, H. Ohno, S. Nagamatsu, H. Ishida
    • Journal Title

      Am J Physiol 294

    • Data Source
      KAKENHI-PROJECT-19591065
  • [Journal Article] Enhanced release of monocyte chemoattractant protein-1 (MCP-1) by high glucose and free fatty acid and its underlying mechanism in MIN6βcells.2008

    • Author(s)
      H. Seki, K. Takahashi, K. Miyokawa, K. Handa, H. Katsuta, S. Yamaguchi, K. Yoshimoto, E. Itagaki, S. Nagamatsu, H. Ishida
    • Journal Title

      J Kyorin Med Soc 39

      Pages: 31-36

    • Data Source
      KAKENHI-PROJECT-19591065
  • [Journal Article] Adiponectin induces insulin secretion in vitro and in vivo at a low glucose concentration2008

    • Author(s)
      Okamoto M, Ohara-Imaizumi M, Kubota N, Hashimoto S, Eto K, Kanno T, Kubota T, Wakui M, Nagai R, Noda M, Nagamatsu S, Kadowaki T
    • Journal Title

      Diabetologia 51

      Pages: 827-835

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Adiponectin induces insulin secretion in vitro and in vivo at a low glucose concentration.2008

    • Author(s)
      Okamoto M, Ohara-Imaizumi M, Kubota N, Hashimoto S, Eto K, Kanno T, Kubota T, Wakui M, Nagai R, Noda M, Nagamatsu S, Kadowaki T
    • Journal Title

      Diabetologia(^#equal contrinution) 51

      Pages: 827-835

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Journal Article] Imaging of insulin exocvtosis in GK rat beta cells subjected to long-term elinide or sulphonylurea treatment.2008

    • Author(s)
      Kawai J., Ohara-Imaizumi M.Nagamatsu S.(他9名)
    • Journal Title

      Biochem.J. 412

      Pages: 93-101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Change in long-spacing collagen in descemet's membrane of diabetic Goto-Kakizaki rats and its suppression by antidiabetic agents2008

    • Author(s)
      Akimoto Y, Sawada H, Ohara-Imaizumi M, Nagamatsu S & Kawakami H.
    • Journal Title

      Exp Diabetes Res

      Volume: 2008 Pages: 81834-81834

    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Adiponectin induces insulin secretion in vitro and in vivo at a low glucose concentration2008

    • Author(s)
      Okamoto M., Ohara-Imaizumi M., Nagamatsu S.(他9名)
    • Journal Title

      Diabetologia 51

      Pages: 827-835

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Imaging Exocytosis of Single Insulin Secretory Granules With TIRF Microscopy.2008

    • Author(s)
      Nagamatsu S, Ohara-Imaizumi M
    • Journal Title

      Methods in Mol Biol 440

      Pages: 259-268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Journal Article] Change in long-spacing collagen in descemet's membrane of diabetic Goto-Kakizaki rats and its suppression by antidiabetic agents.2008

    • Author(s)
      Akimoto Y, Sawada H, Ohara-Imaizumi M, Nagamatsu S, Kawakami H
    • Journal Title

      Exp Diabetes Res 818341

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Imaging Exocytosis of Single Insulin Secretory Granules With TIRF Microscopy.2008

    • Author(s)
      Nagamatsu S & Ohara-Imaizumi
    • Journal Title

      Methods Mol Biol 440

      Pages: 259-268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Change in long-spacing collagen in descemet's membrane of diabetic Goto-Kakizaki rats and its suppression by antidiabetic agents.2008

    • Author(s)
      Akimoto Y, Sawada H, Ohara-Imaizumi M, Nagamatsu S, Kawakami H
    • Journal Title

      Exp Diabetes Res 2008

      Pages: 81834-81834

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Journal Article] Change in long-spacing collagen in descemet's membrane of diabetic Goto-Kakizaki rats and its suppression by antidiabetic agents.2008

    • Author(s)
      Akimoto Y, Ohara-Imaizumi M, Nagamatsu S., (他2名)
    • Journal Title

      Exp Diabetes Res2008

      Pages: 81834-81834

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Journal Article] Change in long-spacing collagen in descemet's membrane of diabetic Goto-Kakizaki rats and its suppression by antidiabetic agents.2008

    • Author(s)
      Akimoto Y, Ohara-Imaizumi M, Nagamatsu S., (他2名)
    • Journal Title

      Exp Diabetes Res2008

      Pages: 81834-81834

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Journal Article] Adiponectin induces insulin secretion in vitro and in vivo at a low glucose concentration2008

    • Author(s)
      Okamoto, M*, Ohara-Imaizumi, M*, Kubota, N, Hashimoto, S, Eto, K, Kanno, T, Kubota, T, Wakui, M, Nagai, R, Noda, M, Nagamatsu, S, Kadowaki, T
    • Journal Title

      Diabetologia 51

      Pages: 827-835

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Elevation of the post-translational modification of proteins by 0-linked N-acetylglucosamine leads to deterioration of the glucose-stimulated insulin secretion in the pancreas of diabetic Goto-Kakizaki rats.2007

    • Author(s)
      Akimoto Y, Hart GW, Wells L, Vosseller K, Yamamoto K, Munetomo E, Ohara-Imaizumi M, Nishiwaki C, Nagamatsu S, Hirano H, Kawakami H
    • Journal Title

      Glycobiology.Feb 17(2)

      Pages: 127-140

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390108
  • [Journal Article] Imaging exoocvtosis of single insulin secretory granules with TIRF microscopy.2007

    • Author(s)
      Nagamatsu S, Ohara-Imaizumi M,
    • Journal Title

      Methods Mol. Biol. 440

      Pages: 259-268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Protein kinase Cdelta plays a non-redundant role in insulin secretion in pancreatic beta cells2007

    • Author(s)
      Uchida, T., Ohara-ImaizumiM., Nagamatsu S.(他8名)
    • Journal Title

      J Biol Chem 282

      Pages: 2707-2716

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Elevation of the post-translational modification of proteins by O-linked N-acetylglucosamine leads to deterioration of the glucose-stimulated insulin secretion in the pancreas of diabetic Goto-Kakizaki rats.2007

    • Author(s)
      Akimoto Y, Ohara-Imaizumi M, Nagamatsu S, (他8名)
    • Journal Title

      Glycobiology 17

      Pages: 127-40

    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Imaging exoocytosis of single insulin secretory granules with TIRF microscopy2007

    • Author(s)
      Nagamatsu S, Ohara-Iniaizuini M
    • Journal Title

      Methods Mol.Biol. 440

      Pages: 259-268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18050033
  • [Journal Article] InsP_7 debut in insulin release2007

    • Author(s)
      Nagamatsu S., Ohara-Imaizumi M.
    • Journal Title

      Science 318

      Pages: 1249-1250

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Imaging analysis reveals mechanistic differences between first- and second-phase insulin exocvtosis.2007

    • Author(s)
      Ohara-Imaizumi M, Nagamatsu S.(他9名)
    • Journal Title

      J Cell Biol 177

      Pages: 695-705

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] EphA-Ephrin-A-mediated beta cell communication regulates insulin secretion from pancreatic islets2007

    • Author(s)
      Konstantinova, I., Ohara-Imaizumi M., Nagamatsu S.(他8名)
    • Journal Title

      Cell 129

      Pages: 359-370

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Protein kinase Cdelta plays a non-redundant role in insulin secretion in pancreatic beta cells.2007

    • Author(s)
      Uchida T, Ohara-Imaizumi M, Nagamatsu S, (他9名)
    • Journal Title

      J Biol Chem. 282(4)

      Pages: 2707-2716

    • Data Source
      KAKENHI-PROJECT-18050033
  • [Journal Article] インスリン分泌機構の画像解析2007

    • Author(s)
      永松信哉, 今泉美佳
    • Journal Title

      内分泌・糖尿病科 24

      Pages: 69-75

    • Data Source
      KAKENHI-PROJECT-18050033
  • [Journal Article] Protein kinase Cdelta plays a non-redundant role in insulin secretion in pancreatic beta cells.2007

    • Author(s)
      Uchida T, Ohara-Imaizumi M, Nagamatsu S, (他9名)
    • Journal Title

      J Biol Chem. 282

      Pages: 2707-16

    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Protein kinase Cdelta plays a non-redundant role in insulin secretion in pancreatic beta cells.2007

    • Author(s)
      Uchida.T., Ohara-Imaizumi M., Nagamatsu S., (他9名)
    • Journal Title

      J Biol Chem. 282(4)

      Pages: 2707-2016

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390108
  • [Journal Article] Imaging analysis reveals mechanistic differences between first- and second-phase insulin exocytosis2007

    • Author(s)
      Ohara-Imaizumi, M., Fujiwara, T., Nakamichi, Y., Okamura, T., Akimoto, Y., Kawai, J., Matsushima, S., Kawakami, H., Watanabe, T., Akagawa, K., Nagamatsu, S
    • Journal Title

      J Cell Biol 177

      Pages: 695-705

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Imaging analysis reveals mechanistic differences between first- and second-phase insulin exocytosis2007

    • Author(s)
      Ohara-lmaizumi M., Nagamatsu S.(他9名)
    • Journal Title

      J Cell Biol 177

      Pages: 695-705

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] InsP_7 debut in insulin release.2007

    • Author(s)
      Nagamatsu S, Ohara-Imaizumi M,
    • Journal Title

      Science. 318

      Pages: 1249-1250

    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Protein kinase Cdelta plays a non-redundant role in insulin secretion in pancreatic beta cells. J Biol Chem2007

    • Author(s)
      Uchida, T, Iwashita, N, Ohara-Imaizumi, M, Ogihara, T, Nagai, S, Choi, JB, Tamura, Y, Tada, N, Kawamori, R, Nakayama, KI, Nagamatsu, S, Watada, H
    • Journal Title

      Jan 26 282 (4)

      Pages: 2707-2716

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Elevation of the post-translational modification of proteins by O-linked N-acetylglucosamine leads to deterioration of the glucose-stimulated insulin secretion in the pancreas of diabetic Goto-Kakizaki rats.2007

    • Author(s)
      Akimoto Y, Ohara-Imaizumi M, Nagamatsu S, (他8名)
    • Journal Title

      Glycobiology. 17(2)

      Pages: 127-140

    • Data Source
      KAKENHI-PROJECT-18050033
  • [Journal Article] EphA-Ephrin-A-mediated beta cell communication regulates insulin secretion from pancreatic islets2007

    • Author(s)
      Konstantinova, I., Nikolova, G, Ohara-Imaizumi, M., Meda, P., Kucera, T., Zarbalis, K., Wurst, W., Nagamatsu, S., Lammert, E
    • Journal Title

      Cell 129

      Pages: 359-370

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Elevation of the post-translational modification of proteins by O-linked N-acetylglucosamine leads to deterioration of the glucose-stimulated insulin secretion in the pancreas of diabetic Goto-Kakizaki rats2007

    • Author(s)
      Akimoto, Y., Hart, G W., Wells, L., Vosseller, K., Yamamoto, K., Munetomo, E., Ohara-Imaizumi, M., Nishiwaki, C., Nagamatsu, S., Hirano, H., Kawakami, H
    • Journal Title

      Glycobiology 17

      Pages: 127-140

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Elevation of the post-translational modification of proteins by O-linked N-acetylglucosamine leads to deterioration of the glucose-stimulated insulin secretion in the pancreas of diabetic Goto-Kakizaki rats2007

    • Author(s)
      Akimoto, Y., Ohara-Imaizumi M., Nagamatsu S.(他8名)
    • Journal Title

      Glycobiology 17

      Pages: 127-140

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] 膵B細胞のアクティブゾーンを構成する分子群2007

    • Author(s)
      泉美佳, 大塚稔久, 永松信哉
    • Journal Title

      内分泌・糖尿病科 25

      Pages: 265-272

    • Data Source
      KAKENHI-PROJECT-18050033
  • [Journal Article] インスリン分泌機構の画像解析2007

    • Author(s)
      永松 信哉, 今泉 美佳
    • Journal Title

      内分泌・糖尿病科 24

      Pages: 69-75

    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Imaging exoocytosis of single insulin secretory granules with TIRF microscopy2007

    • Author(s)
      Nagamatsu S., Ohara-Imaizumi M.
    • Journal Title

      Methods Mol.Biol 440

      Pages: 259-268

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Imaging analysis reveals mechanistic differences between first- and second- hase insulin exocytosis.2007

    • Author(s)
      Ohara-Imaizuini M, Nagamatsu S. (他9名)
    • Journal Title

      JCell Biol 177

      Pages: 695-705

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18050033
  • [Journal Article] Imaging exoocytosis of single insulin secretory granules with TIRF microscopy2007

    • Author(s)
      Nagamatsu, S., Ohara-Imaizumi, M
    • Journal Title

      Methods Mol. Biol 440

      Pages: 259-268

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] InsP7 debut in insulin release2007

    • Author(s)
      Nagamatsu, S., Ohara-Imaizumi, M
    • Journal Title

      Science 318

      Pages: 1249-1250

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] InsP_7 debut in insulin release.2007

    • Author(s)
      Nagamatsu S, Ohara-Iniaizuini M
    • Journal Title

      Science. 318

      Pages: 1249-1250

    • Data Source
      KAKENHI-PROJECT-18050033
  • [Journal Article] Protein kinase C delta plays a non-redundant role in insulin secretion in pancreatic beta cells.2007

    • Author(s)
      Uchida T, Iwashita N, Ohara-Imaizumi M, Ogihara T, Nagai S, Choi JB, Tamura Y, Tada N, Kawamori R, Nakayama KI, Nagamatsu S, Watada H
    • Journal Title

      J Biol Chem 282(4)

      Pages: 2707-2716

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390108
  • [Journal Article] Imaging analysis reveals mechanistic differences between first and second phase insulin exocytosis.2007

    • Author(s)
      Ohara-Imaizumi M, Nagamatsu S. (他9名)
    • Journal Title

      J. Cell. Biol. In press

    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] 膵β細胞のアクティブゾーンを構成する分子群2007

    • Author(s)
      今泉 美佳、大塚 稔久、永松 信哉
    • Journal Title

      内分泌・糖尿病科 25

      Pages: 265-272

    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Imaging docking and fusion of insulin granules induced by antidiabetes agents:sulfonylurea and glinide drugs preferentially mediate the fusion of newcomer,but not previously docked,insulin granules2006

    • Author(s)
      Nagamatsu S, , Ohara-Imaizumi M., (他3名)
    • Journal Title

      Diabetes 55

      Pages: 2819-2825

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Insulin exocytotic mechanism by imaging technique.2006

    • Author(s)
      Ohara-Imaizumi M., Nagamatsu S.
    • Journal Title

      J Biochem (Tokyo) 140(1)

      Pages: 1-5

    • NAID

      10018843301

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390108
  • [Journal Article] Insulin exocytotic mechanism by imaging technique.2006

    • Author(s)
      Ohara-Imaizumi M., Nagamatsu S.
    • Journal Title

      J Biochem (Tokyo). 140(1)

      Pages: 1-5

    • NAID

      10018843301

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390108
  • [Journal Article] Imaging docking and fusion of insulin granules induced by antidiabetes agents : sulfonylurea and glinide drugs preferentially mediate the fusion of newcomer, but not previously docked, insulin granules2006

    • Author(s)
      Nagamatsu, S., Ohara-Imaizumi, M., Nakamichi, Y, Kikuta, T., Nishiwaki, C
    • Journal Title

      Diabetes 55

      Pages: 2819-2825

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Intracellular dynamics observed by mode switching of microscope with a light incidence to the interface at alternate angles through the ultra high NA objective2006

    • Author(s)
      Wakazono, Y., Sakurai, T., Ohara-Imaizumi, M., Nagamatsu, S., Yamamoto, S., Terakawa. S
    • Journal Title

      Proc. SPIE 6088

      Pages: 449-454

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Imaging docking and fusion of insulin granules induced by antidiabetes agents : sulfonylurea and glinide drugs preferentially mediate the fusion of newcomer, but not previously docked, insulin granules.2006

    • Author(s)
      Nagamatsu S, Ohara-Imaizumi M, (他3名)
    • Journal Title

      Diabetes 55

      Pages: 2819-25

    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] TIRF Microscopy Analysis of the Mechanism of Insulin Exocytosis.2006

    • Author(s)
      Nagamatsu S
    • Journal Title

      Endocr J.Aug 53(4)

      Pages: 433-440

    • NAID

      10019269449

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390108
  • [Journal Article] Insulin exocytotic mechanism by imaging technique.2006

    • Author(s)
      Ohara-Imaizumi M, Nagamatsu S.
    • Journal Title

      J Biochem(Tokyo). 140(1)

      Pages: 1-5

    • NAID

      10018843301

    • Data Source
      KAKENHI-PROJECT-18050033
  • [Journal Article] Imaging Docking and Fusion of Insulin Granules Induced by Antidiabetes Agents : Sulfonylurea and Glinide Drugs Preferentially Mediate the Fusion of Newcomer, but Not Previously Docked, Insulin Granules.2006

    • Author(s)
      Nagamatsu S., Ohara-Imaizumi M., (他3名)
    • Journal Title

      Diabetes 55

      Pages: 2819-2825

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390108
  • [Journal Article] TIRF Microscopy Analysis of the Mechanism of Insulin Exocytosis.2006

    • Author(s)
      Nagamatsu S
    • Journal Title

      Endocrine J 53

      Pages: 433-440

    • NAID

      10019269449

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390108
  • [Journal Article] Intracellular dynamics observed by mode switching of microscope with a light incidence to thevnterface at alternate angles through the ultra high NA objective2006

    • Author(s)
      Wakazono, Y., Ohara-Imaizumi M., Nagamatsu S.(他3名)
    • Journal Title

      Proc.SPIE 6088

      Pages: 449-454

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Imaging docking and fusion of insulin granules induced by antidiabetes agents : sulfonylurea and glinide drugs preferentially mediate the fusion of newcomer, but not previously docked, insulin granules.2006

    • Author(s)
      Nagamatsu S, Ohara-Imaizumi M, Nakamichi Y, Kikuta T, Nishiwaki C
    • Journal Title

      Diabetes.Oct 55(10)

      Pages: 2819-2825

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390108
  • [Journal Article] Insulin exocytotic mechanism by imaging technique.2006

    • Author(s)
      Ohara-Imaizumi M, Nagamatsu S.
    • Journal Title

      J Biochem (Tokyo). 140

      Pages: 1-5

    • NAID

      10018843301

    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Imaging docking and fusion of insulin granules induced by antidiabetes agents : sulfonylurea and glinide drugs preferentially mediate the fusion of newcomer, but not previously docked, insulin granules.2006

    • Author(s)
      Nagamatsu S, Ohara-Imaizumi M
    • Journal Title

      Diabetes 55(10)

      Pages: 2819-2825

    • Data Source
      KAKENHI-PROJECT-18050033
  • [Journal Article] Elevation of the post-translational modification of proteins by O-linked N-acetylglucosamine leads to deterioration of the glucose-stimulated insulin secretion in the pancreas of diabetic Goto-Kakizaki rats2006

    • Author(s)
      Akimoto Y., Ohara-Imaizumi M., Nagamatsu S., (他9名)
    • Journal Title

      Glycobiology. 17(2):

      Pages: 127-140

    • Data Source
      KAKENHI-PROJECT-15390108
  • [Journal Article] Elevation of the post-translational modification of proteins by O-linked N-acetylglucosamine leads to deterioration of the glucose-stimulated insulin secretion in the pancreas of diabetic Goto-Kakizaki rats2006

    • Author(s)
      Akimoto Y., Ohara-Imaizumi M., Nagamatsu S., (他9名)
    • Journal Title

      Glycobiology. 17(2)

      Pages: 127-140

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390108
  • [Journal Article] Activators of AMP-activated protein kinase enhance GLUT4 translocation and its glucose transport activity in 3T3L1 adipocytes.2005

    • Author(s)
      Yamaguchi S., Ohara-Imaizumi M., Nagamatsu S.(他8名)
    • Journal Title

      Am J Physiol Endocrinol metab. 289

      Pages: 3289-3300

    • Data Source
      KAKENHI-PROJECT-15390108
  • [Journal Article] Renin-angiotensin system modulates oxidative stress-induced endothelial cell apoptosis in rats2005

    • Author(s)
      Akishita, M., Nagai, K., Xi, H., Yu, W., Sudoh, N., Watanabe, T., Ohara-Imaizumi, M., Nagamatsu, S., Kozaki, K., Horiuchi, M., Toba, K
    • Journal Title

      Hypertension 45

      Pages: 1188-1193

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Renin-angiotensin system modulates oxidative stress-induced endothelial cell apoptosis in rats.2005

    • Author(s)
      Akishita M., Ohara-Imaizumi M., Nagamatsu S.(他9名)
    • Journal Title

      Hypertension 45

      Pages: 1188-1193

    • Data Source
      KAKENHI-PROJECT-16044240
  • [Journal Article] Rab27a mediates the fight docking of insulin granules onto the plasma membrane during glucose stimulation2005

    • Author(s)
      Kasai K, Ohara-ImaizumiM., Nagamatsu S.(他7名)
    • Journal Title

      J Clin Invest 115

      Pages: 388-396

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] ELKS,a protein structurally related to the active zone-associated protein CAST,is expressed in pancreatic beta cells and functions in insulin exoc ytosis:interaction of ELKS with exocytotic machinery analyzed by total internal reflection fluorescence microscopy2005

    • Author(s)
      Ohara-Imaizumi M., Nagamatsu S.(他9名)
    • Journal Title

      Mol Biol Cell 16

      Pages: 3289-3300

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] ELKS, a protein structurally related to the active zone-associated protein CAST, is expressed in pancreatic β cells and functions in insulin exocytosis : Interaction of ELKS with exocytotic machinery analyzed by total internal reflection fluorescence microscopy.2005

    • Author(s)
      Ohara-lmaizumi M, (他9名) Nagamatsu S
    • Journal Title

      Mol. Biol. Cell 16

      Pages: 3289-3300

    • Data Source
      KAKENHI-PROJECT-15390108
  • [Journal Article] インスリン開口放出のリアルタイム可視化技術2005

    • Author(s)
      今泉美佳, 永松信哉
    • Journal Title

      日本薬理学雑誌 126

      Pages: 399-405

    • NAID

      10018621698

    • Data Source
      KAKENHI-PROJECT-15390108
  • [Journal Article] 2相性インスリン分泌機構と糖尿病におけるインスリン分泌不全2005

    • Author(s)
      永松信哉
    • Journal Title

      Nephrology Frontier 4

      Pages: 63-67

    • Data Source
      KAKENHI-PROJECT-15390108
  • [Journal Article] Renin-angiotensin system modulates oxidative stress-induced endothelial cell apoptosis in rats.2005

    • Author(s)
      Akishita M., Ohara-Imaizumi M., Nagamatsu S.(他9名)
    • Journal Title

      Hypertension 45

      Pages: 1188-1193

    • Data Source
      KAKENHI-PROJECT-15390108
  • [Journal Article] Renin-angiotensin system modulates oxidative stress-induced endothelial cell anontosis in rats2005

    • Author(s)
      Akishita M., Ohara-Imaizumi M., Nagamatsu S.(他8名)
    • Journal Title

      Hypertension 45

      Pages: 1188-1193

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Docking and fusion of insulin secretory granules in SUR1 knock out mouse beta-cells observed by total internal reflection fluorescence microscopy.2005

    • Author(s)
      Kikuta, T., Ohara-Imaizumi, M., Nakazaki, M., Nishiwaki, C., Nakamichi, Y, Tei, C., Aguilar-Bryan, L., Bryan, J., Nagamatsu, S.
    • Journal Title

      FEBS Lett. 579

      Pages: 1602-1606

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Journal Article] Rab27a mediates the tight docking of insulin granules onto the plasma membrane during glucose stimulation2005

    • Author(s)
      Kasai, K., Ohara-Imaizumi, M., Takahashi, N., Mizutani, S., Zhao, S., Kikuta, T., Kasai, H., Nagamatsu, S., Gomi, H., Izumi, T
    • Journal Title

      J Clin Invest 115

      Pages: 388-396

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] インスリン開口放出のリアルタイム可視化技術2005

    • Author(s)
      今泉美佳, 永松信哉
    • Journal Title

      日本薬理学雑誌 126

      Pages: 399-405

    • NAID

      10018621698

    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] ELKS, a protein structurally related to the active zone- associated protein CAST, is expressed in pancreatic □ cells and functions in insulin exocytosis : Interaction of ELKS with exocytotic machinery analyzed by total internal reflection fluorescence microscopy.2005

    • Author(s)
      Ohara-Imaizumi M, (他9名) Nagamatsu S
    • Journal Title

      Mol.Biol.Cell 16

      Pages: 3289-3300

    • Data Source
      KAKENHI-PROJECT-16044240
  • [Journal Article] Activators of AMP-activated protein kinase enhance GLUT4 translocation and its glucose transport activity in 3T3L1 adipocytes.2005

    • Author(s)
      Yamaguchi S., Ohara-Imaizumi M., Nagamatsu S.(他8名)
    • Journal Title

      Am J Physiol Endocrinol Metab. 289

      Pages: 3289-3300

    • Data Source
      KAKENHI-PROJECT-16044240
  • [Journal Article] Rab27a mediates the tight docking of insulin granules onto the plasma membrane during glucose stimulation.2005

    • Author(s)
      Kasai, K., Ohara-Imaizumi, M., Takahashi, N., Mizutani, S., Zhao, S., Kikuta, T., Kasai, H., Nagamatsu, S., Gomi, H., Izumi, T.
    • Journal Title

      J.Clin.Invest. 115

      Pages: 388-396

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Journal Article] ELKS, a protein structurally related to the active zone-associated protein CAST, is expressed in pancreatic β cells and functions in insulin exocytosis : Interaction of ELKS with exocytotic machinery analyzed by total internal reflection fluorescence microscopy.2005

    • Author(s)
      Ohara-Imaizumi M, (他9名) Nagamatsu S
    • Journal Title

      Mol. Biol. Cell 16

      Pages: 3289-3300

    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Docking and fusion of insulin secretory granules in SURI knock out mouse beta-cells observed by total internal reflection fluorescence microscopy2005

    • Author(s)
      Kikuta T, Ohara-ImaizumiM., NagamatsuS.(他7名)
    • Journal Title

      FEBS Lett 579

      Pages: 1602-1606

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Docking and fusion of insulin secretory granules in SUR1 knock out mouse beta-cells observed by total internal reflection fluorescence microscopy2005

    • Author(s)
      Kikuta, T., Ohara-Imaizumi, M., Nakazaki, M., Nishiwaki, C., Nakamichi, Y, Tei, C., Aguilar-Bryan, L., Bryan, J., Nagamatsu, S
    • Journal Title

      FEBS Lett 579

      Pages: 1602-1606

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] Renin-angiotensin system modulates oxidative stress-induced endothelial cell apoptosis in rats.2005

    • Author(s)
      Akishita M., Ohara-Imaizumi M., Nagamatsu S.(他9名)
    • Journal Title

      Hypertension 45

      Pages: 1188-1193

    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] ELKS, a protein structurally related to the active zone-associated protein CAST, is expressed in pancreatic beta cells and functions in insulin exocytosis : interaction of ELKS with exocytotic machinery analyzed by total internal reflection fluorescence microscopy2005

    • Author(s)
      Ohara-Imaizumi, M., Ohtsuka, T., Matsushima, S., Akimoto, Y., Nishiwaki, C., Nakamichi, Y., Kikuta, T., Nagai, S., Kawakami, H., Watanabe, T., Nagamatsu, S
    • Journal Title

      Mol Biol Cell 16

      Pages: 3289-3300

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Journal Article] インスリン開口放出のリアルタイム可視化技術2005

    • Author(s)
      今泉美佳, 永松信哉
    • Journal Title

      日本薬理学雑誌 126

      Pages: 399-405

    • NAID

      10018621698

    • Data Source
      KAKENHI-PROJECT-16044240
  • [Journal Article] Osteoclastic function is accelerated in male patients with type 2 diabetes mellitus : the preventive role of osteoclastogenesis inhibitory factor/osteoprotegerin (OCIF/OPG) on the decrease of bone mineral density.2005

    • Author(s)
      Suzuki K., Nagamatsu S.(他8名)
    • Journal Title

      Diabetes Res Clin Practice 68

      Pages: 117-125

    • Data Source
      KAKENHI-PROJECT-15390108
  • [Journal Article] Correlation of syntaxin-1 and SNAP-25 clusters with docking and fusion of insulin granules analyzed by total internal reflection fluorescence microscopy.2004

    • Author(s)
      Ohara-Imaizumi, M., Nishiwaki, C., Nakamichi, Y., Kikuta, T., Nagai, S., Nagamatsu, S.
    • Journal Title

      Diabetologia. 47(12)

      Pages: 2200-2207

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Journal Article] Functions of pancreatic beta cells and adipocytes in bombesin receptor subtype-3-deficient mice.2004

    • Author(s)
      Nakamichi, Y., Wada, E., Aoki, K., Ohara-Imaizumi, M., Kikuta, T., Nishiwaki, C., Matsushima, S., Watanabe, T., Wada, K., Nagamatsu, S.
    • Journal Title

      Biochem.Biophys.Res.Commun. 318

      Pages: 698-703

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Journal Article] Site of docking and fusion of insulin secretory granules in live MIN6 □ cells analyzed by TAT-conjugated anti-syntaxin 1 antibody and total internal reflection fluorescence microscopy.2004

    • Author(s)
      Ohara-Imaizumi M, Nagamatsu S et al.
    • Journal Title

      J Biol Chem 279

      Pages: 8403-8408

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Journal Article] Site of docking and fusion of insulin secretory granules in live MIN6 β cells analyzed by TAT-conjugated anti-syntaxin 1 antibody and total internal reflection fluorescence microscopy.2004

    • Author(s)
      Ohara-Imaizumi, M., Nishiwaki, C., Kikuta, T., Kumakura, K., Nakamichi, Y., Nagamatsu, S.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 8403-8408

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Journal Article] TIRF imaging of docking and fusion of single insulin granule motion in primary rat pancreatic beta-cells : different behaviour of granule motion between normal and Goto-Kakizaki diabetic rat beta-cells.2004

    • Author(s)
      Ohara-Imaizumi, M., Nishiwaki, C., Kikuta, T., Nagai, S., Nakamichi, Y., Nagamatsu, S.
    • Journal Title

      Biochem.J. 381

      Pages: 13-18

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Journal Article] The cytokine interleukin-1beta reduces the docking and fusion of insulin granules in pancreatic beta-cells, preferentially decreasing the first phase of exocytosis2004

    • Author(s)
      Ohara-Imaizumi, M., Cardozo, A.K., Kikuta, T., Eizirik, D.L., Nagamatsu, S.
    • Journal Title

      J.Biol.Chem. 279

      Pages: 41271-41274

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Journal Article] Secretory granules are recaptured largely intact after stimulated exocytosis in cultured endocrine cells.2003

    • Author(s)
      Taraska, J.W., Perrais, D., Ohara-Imaizumi, M., Nagamatsu, S., Almers, W.
    • Journal Title

      Proc.Natl.Acad.Sci. USA 100

      Pages: 2070-2075

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Journal Article] Visualizing exocytosis of insulin granules with evanescent wave microscopy.2003

    • Author(s)
      Ohara-Imaizumi, M., Nagamatsu, S.
    • Journal Title

      Seikagaku 75

      Pages: 49-54

    • NAID

      80015773647

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Journal Article] PPAR-gamma overexpression suppresses glucose-induced proinsulin biosynthesis and insulin release synergistically with pioglitazone in MIN6 cells.2003

    • Author(s)
      Nakamichi, Y., Kikuta, T., Ito, E., Ohara-Imaizumi.M., Nishiwaki, C., Ishida, H., Nagamatsu, S.
    • Journal Title

      Biochem.Biophys.Res.Commun. 306

      Pages: 832-836

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Journal Article] インスリン開口放出の可視化(ミニレビュー)2003

    • Author(s)
      今泉美佳, 永松信哉
    • Journal Title

      生化学 75

      Pages: 49-54

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Journal Article] An insulin-related peptide expressed in 3T3L1 adipocytes is localized in GLUT4 vesicles and secreted in response to exogenous insulin, which augments the insulin-stimulated glucose uptake.2003

    • Author(s)
      Nakamichi, Y., Ohara-Imaizumi, M., Ishida, H., Nagamatsu, S.
    • Journal Title

      J.Cell Sci. 116

      Pages: 73-79

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Journal Article] An Insulin-related peptide expressed in response to exogenous insulin, which augments the muslin-stimulated glucose uptake.2003

    • Author(s)
      Nakamichi Y., Ohara-Imaizumi M., Ishida H., Nagamatsu S.
    • Journal Title

      J.Cell Sci. 116

      Pages: 73-79

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Journal Article] Transduction of MIN6 beta cells with TAT-syntaxin SNARE motif inhibits insulin exocytosis in biphasic insulin release in a distinct mechanism analyzed by evanescent wave microscopy.2002

    • Author(s)
      Ohara-Imaizumi, M., Nakamichi, Y., Nishiwaki, C., Nagamatsu, S.
    • Journal Title

      J.Biol.Chem. 277

      Pages: 50805-50811

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Journal Article] Monitoring of exocytosis and endocytosis of insulin secretory granules in the pancreatic β cell line MIN6 using pH-sensitive green fluorescent protein (pHluorin)and confocal laser microscopy.2002

    • Author(s)
      Ohara-Imaizumi M., Nagamatsu S.(他4名)
    • Journal Title

      Biochem.J. 363

      Pages: 73-80

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Journal Article] インスリン開口放出機構とSNARE蛋白質2002

    • Author(s)
      永松信哉, 今泉美佳
    • Journal Title

      日本臨床 60

      Pages: 213-218

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Journal Article] Imaging exocytosis of single insulin secretory granules with evanescent wave microscopy.2002

    • Author(s)
      Ohara-Imaizumi M, Nagamatsu S.(他3名)
    • Journal Title

      J.Biol.Chem. 77

      Pages: 3805-3808

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Journal Article] Molecular mechanism of insulin exocytosis and the role of SNARE proteins.2002

    • Author(s)
      Nagamatsu, S., Ohara-Imaizumi, M
    • Journal Title

      Nihonrinsho 60

      Pages: 213-218

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Journal Article] Transduction of MIN6 β cell with TAT-Syntaxin SNARE Motif Inhibits Insulin Exocytosis in Biphasic Insulin Release in a Distinct Mechanism Analyzed by Evanescent Wave Microscopy.2002

    • Author(s)
      Ohara-Imaizumi M., Nakamichi Y., Nishiwaki C., Nagamatsu S
    • Journal Title

      J.Biol.Chem. 277

      Pages: 50805-50811

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Journal Article] Decreased marble burying behavior in female mice lacking neuromedin-B receptor (NMB-R) implies the involvement of NMB/NMB-R in 5-HT neuron function.2002

    • Author(s)
      Yamada, K., Wada, E., Yamano, M., Sun, Y.J., Ohara-Imaizumi, M., Nagamatsu, S., Wada, K.
    • Journal Title

      Brain Res. 942

      Pages: 71-78

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Journal Article] Monitoring of exocytosis and endocytosis of insulin secretory granules in the pancreatic beta-cell line MIN6 using pH-sensitive green fluorescent protein (pHluorin) and confocal laser microscopy.2002

    • Author(s)
      Ohara-Imaizumi, M., Nakamichi, Y., Tanaka, T., Katsuta, H., Ishida, H., Nagamatsu, S.
    • Journal Title

      Biochem.J. 363

      Pages: 73-80

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-14570130
  • [Journal Article] Imaging analysis reveals mechanistic differences between first- and second-phase insulin exocytosis.

    • Author(s)
      Ohara-Imaizumi M, Nagamatsu S.(他9名)
    • Journal Title

      J.Cell.Biol. (In press)

    • Data Source
      KAKENHI-PROJECT-18050033
  • [Presentation] VAMP7 regulates autophagy to maintain mitochondrial homeostasis and to control insulin secretion in pancreatic β-cells.2017

    • Author(s)
      Aoyagi K., Itakura M., Nakamichi Y., Nishiwaki C., Torii S., Nagamatsu S.,& Ohara-Imaizumi M.
    • Organizer
      第60回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-26460396
  • [Presentation] VAMP7 regulates autophagy to maintain mitochondrial homeostasis and to control insulin secretion in pancreatic b-cells.2017

    • Author(s)
      Aoyagi K., Itakura M., Nakamichi Y., Nishiwaki C., Torii S., Nagamatsu S., Ohara-Imaizumi M.
    • Organizer
      第60回日本糖尿病学会年次学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2017-05-18
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460396
  • [Presentation] Role of active zone protein ELKS in insulin secretion from pancreatic β-cells.2017

    • Author(s)
      Ohara-Imaizumi M. Hida, Y., Yoshida, M., Aoyagi, K., Ohkura, M., Sakimura, K., Nakai, J., Kakei, M., Nagamatsu, S., Ohtsuka, T.
    • Organizer
      第11回Diabetes Leading-edge Conference
    • Data Source
      KAKENHI-PROJECT-26460396
  • [Presentation] インスリン開口分泌におけるアクティブゾーン構成タンパク質ELKSの役割2016

    • Author(s)
      今泉美佳、青柳共太、吉田昌史、飛田耶馬人、岸本拓磨、中道洋子、西脇知世乃、﨑村建司、大塚稔久、加計正文、永松信哉
    • Organizer
      第59回日本糖尿病学会年次学術集会
    • Place of Presentation
      京都
    • Year and Date
      2016-05-19
    • Data Source
      KAKENHI-PROJECT-26460396
  • [Presentation] VAMP7はオートファジーによるミトコンドリア恒常性維持機構を介して膵β細胞からの第2相インスリン分泌を制御する: VAMP7 regulates autophagy to maintain mitochondrial homeostasis and to control the second phase insulin secretion in pancreatic β-cells2015

    • Author(s)
      青柳共太、今泉美佳、板倉誠、鳥居征司、岸本拓磨、原田彰宏、秋元義弘、高橋正身、永松信哉
    • Organizer
      第67回日本細胞生物学会大会
    • Place of Presentation
      東京
    • Year and Date
      2015-06-30
    • Data Source
      KAKENHI-PROJECT-26460396
  • [Presentation] VAMP7はオートファジーを制御してミトコンドリアの恒常性維持と第2相インスリン分泌を調節する2015

    • Author(s)
      青柳共太、今泉美佳、板倉誠、鳥居征司、秋元義弘、西脇知世乃、中道洋子、岸本拓磨、原田彰宏、高橋正身、永松信哉
    • Organizer
      BMB2015(第38回日本分子生物学会年会、第88回日本生化学会大会 合同大会)
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26460396
  • [Presentation] VAMP7による第2相インスリン分泌の制御機構2015

    • Author(s)
      青柳共太、今泉美佳、板倉誠、鳥居征司、岸本拓磨、西脇知世乃、中道洋子、秋元義弘、原田彰宏、高橋正身、永松信哉
    • Organizer
      第58回日本糖尿病学会年次学術集会
    • Place of Presentation
      山口
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-26460396
  • [Presentation] VAMP7 regulates autophagy to maintain mitochondrial homeostasis and to control second phase insulin secretion in pancreatic β-cells.2015

    • Author(s)
      青柳共太、今泉美佳、西脇知世乃、中道洋子、岸本拓磨、永松信哉
    • Organizer
      第58回日本神経化学会大会
    • Place of Presentation
      大宮
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-26460396
  • [Presentation] 膵β細胞からのインスリン分泌におけるNALCN/mNLF-1 の役割2013

    • Author(s)
      青柳共太, 今泉美佳, Mei Zhen, 永松信哉
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] Acute inhibition of PI3K-PDK1-Akt pathway potentiates glucose-induced insulin secretion through myosinVa pathway in pancreatic beta cells.2013

    • Author(s)
      Aoyagi K, Ohara-Imaizumi M, Nagamatsu S.
    • Organizer
      Beta Cell Workshop 2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] 膵β細胞からのインスリン分泌におけるNALCN/mNLF-1の役割2013

    • Author(s)
      青柳 共太, 今泉 美佳, Mei Zhen, 永松 信哉.
    • Organizer
      文部科学省 科学研究費補助金「新学術領域研究」細胞内ロジスティクス・シンポジウム
    • Place of Presentation
      兵庫
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] Serotonin regulates glucose stimulated insulin secretion from pancreatic β cells during pregnancy.2013

    • Author(s)
      Ohara-Imaizumi M, Kim H, Yoshida M, Fujiwara T, Aoyagi K, Toyofuku Y, Nakamichi Y, Nishiwaki C, Okamura T, Uchida T, Fujitani Y, Akagawa K, Kakei M, Watada H, German MS and Nagamatsu S.
    • Organizer
      73th Scientific Session of American Diabetes Association
    • Place of Presentation
      Chicago, USA
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] Serotonin regulates glucose stimulated insulin secretion from pancreatic β cells during pregnancy2013

    • Author(s)
      Ohara-Imaizumi M, Kim H, Yoshida M, Fujiwara T, Aoyagi K, Toyofuku Y, Nakamichi Y, Nishiwaki C, Okamura T, Uchida T, Fujitani Y, Akagawa K, Kakei M, Watada H, German MS, Nagamatsu S
    • Organizer
      73th Scientific Session of American Diabetes Association
    • Place of Presentation
      Chicago, USA
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] Acute inhibition of PI3K-PDK1-Akt pathway potentiates glucose-induced insulin secretion through myosinVa pathway in pancreatic beta cells2013

    • Author(s)
      Aoyagi K, Ohara-Imaizumi M, Nagamatsu S
    • Organizer
      Beta Cell Workshop 2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] Serotonin regulates glucose stimulated insulin secretion from pancreatic β cells during pregnancy2013

    • Author(s)
      Ohara-Imaizumi M, Kim H, Yoshida M, Fujiwara T, Aoyagi K, Toyofuku Y, Nakamichi Y, Nishiwaki C, Okamura T, Uchida T, Fujitani Y, Akagawa K, Kakei M, Watada H, German MS, Nagamatsu S
    • Organizer
      Beta Cell Workshop 2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] 膵β細胞からのインスリン分泌におけるNALCN/mNLF-1の役割2013

    • Author(s)
      青柳 共太, 今泉 美佳, Mei Zhen, 永松 信哉.
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] 5-HT receptor 3a signaling regulates insulin release from pancreatic beta cells during pregnancy.2013

    • Author(s)
      今泉美佳、吉田昌史、青柳共太、豊福優希子、綿田裕孝、加計正文、永松信哉.
    • Organizer
      第90回日本生理学会大会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] Serotonin regulates glucose stimulated insulin secretion from pancreatic β cells during pregnancy.2013

    • Author(s)
      Ohara-Imaizumi M, Kim H, Yoshida M, Fujiwara T, Aoyagi K, Toyofuku Y, Nakamichi Y, Nishiwaki C, Okamura T, Uchida T, Fujitani Y, Akagawa K, Kakei M, Watada H, German MS and Nagamatsu S.
    • Organizer
      Beta Cell Workshop 2013
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] 膵β細胞からのインスリン分泌におけるNALCN/mNLF-1 の役割2013

    • Author(s)
      青柳共太, 今泉美佳, Mei Zhen, 永松信哉
    • Organizer
      文部科学省科学研究費補助金「新学術領域研究」細胞内ロジスティクス・シンポジウム
    • Place of Presentation
      兵庫
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] 妊娠期膵β細胞でのセロトニンによるインスリン分泌亢進機構.2012

    • Author(s)
      今泉 美佳, 吉田 昌史, 豊福 優希子, 青柳 共太, 中道 洋子, 西脇 知世乃, 加計 正文, 綿田 裕孝, 永松 信哉
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] 第2相インスリン分泌制御におけるPI3K-PDK1-Akt経路の役割の検討.2012

    • Author(s)
      青柳 共太, 今泉 美佳, 西脇 知世乃, 中道 洋子, 永松 信哉.
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] 妊娠期膵β細胞でのセロトニンによるインスリン分泌亢進機構2012

    • Author(s)
      今泉美佳,青柳共太,永松信哉
    • Organizer
      第14回応用薬理シンポジウム
    • Place of Presentation
      甲府
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] 第2相インスリン分泌制御におけるPI-3 kinaseとPDK1-Akt経路の役割の検討2012

    • Author(s)
      青柳共太, 今泉美佳, 永松信哉
    • Organizer
      第16回東京インスリン分泌研究会
    • Place of Presentation
      東京
    • Year and Date
      2012-02-23
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] 妊娠期膵β細胞でのセロトニンによるインスリン分泌亢進機構2012

    • Author(s)
      今泉美佳, 吉田昌史, 豊福優希子, 青柳共太, 中道洋子, 西脇知世乃, 加計正文, 綿田裕孝, 永松信哉
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] 第2相インスリン分泌制御におけるPI-3 kinaseとPDK1-Akt経路の役割の検討2012

    • Author(s)
      青柳共太、今泉美佳、永松信哉
    • Organizer
      第16回東京インスリン分泌研究会
    • Place of Presentation
      東京
    • Year and Date
      2012-02-23
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] Serotonin signaling regulates insulin secretion from pancreatic beta cells during pregnancy2012

    • Author(s)
      Ohara-Imaizumi, M, Aoyagi K, Yoshida M, Kakei M, Nagamatsu S
    • Organizer
      Exocytosis in endocrine cells-linking experiments and theory Lund University Diabetes Centre
    • Place of Presentation
      Malmö, Sweden
    • Invited
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] 第2相インスリン分泌制御におけるPI3K-PDK1-Akt経路の役割の検討2012

    • Author(s)
      青柳共太、今泉美佳、永松信哉
    • Organizer
      文部科学省科学研究費補助金「新学術領域研究」第4回「細胞内ロジスティクス」班会議
    • Place of Presentation
      仙台、宮城
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] 妊娠期膵β細胞でのセロトニンによるインスリン分泌亢進機構.2012

    • Author(s)
      今泉美佳,青柳共太,永松信哉.
    • Organizer
      第14回 応用薬理シンポジウム.
    • Place of Presentation
      甲府
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] 糖尿病原因究明のためのイメージングによるインスリン開口放出機構解明2012

    • Author(s)
      今泉美佳, 青柳共太, 永松信哉
    • Organizer
      文部科学省科学研究費補助金「新学術領域研究」第4回「細胞内ロジスティクス」班会議
    • Place of Presentation
      仙台、宮城
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] Acute inhibition of PI3K-PDK1-Akt pathway potentiates glucose-induced insulin secretion through MyosinVa in pancreatic beta-cells2012

    • Author(s)
      青柳共太, 今泉美佳, 西脇知世乃, 中道洋子, 永松信哉
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      博多
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] 第2相インスリン分泌制御における PI3K-PDK1-Akt 経路の役割の検討2012

    • Author(s)
      青柳共太、今泉美佳、永松信哉
    • Organizer
      文部科学省 科学研究費補助金 「新学術領域研究」第 4 回 「細胞内ロジスティクス」班会議
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] 膵β細胞におけるインスリン分泌機構の最新の情報2012

    • Author(s)
      永松信哉
    • Organizer
      第11回糖尿病を考える会
    • Place of Presentation
      東京
    • Year and Date
      2012-01-20
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] 糖尿病原因究明のためのイメージングによるインスリン開口放出機構解明2012

    • Author(s)
      今泉美佳,青柳共太,永松信哉
    • Organizer
      文部科学省 科学研究費補助金 「新学術領域研究」第 4 回 「細胞内ロジスティクス」班会議
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] Serotonin signaling regulates insulin secretion from pancreatic beta cells during pregnancy.2012

    • Author(s)
      Ohara-Imaizumi M, Aoyagi K, Yoshida M, Kakei M and Nagamatsu S.
    • Organizer
      Exocytosis in endocrine cells -linking experiments and theory
    • Place of Presentation
      Malmo, Sweden
    • Invited
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] インスリン分泌顆粒の可視化とインクレチンによる制御機構2012

    • Author(s)
      永松信哉
    • Organizer
      第4回糖尿病治療の新たなステージを考える会
    • Place of Presentation
      金沢
    • Year and Date
      2012-03-06
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] 第2相インスリン分泌制御におけるPI3K-PDK1-Akt経路の役割の検討2012

    • Author(s)
      青柳共太, 今泉美佳, 西脇知世乃, 中道洋子, 永松信哉
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] CDKAL1の第1相インスリン分泌における役割2011

    • Author(s)
      今泉美佳, 永松信哉, 他9名
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] Acute inhibition of PI3K-PDK1-Akt pathway potentiates glucose-induced insulin secretion in pancreatic b-cells2011

    • Author(s)
      青柳共太, 永松信哉, 他3名
    • Organizer
      第84回日本生化学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] CDKAL1 の第1相インスリン分泌における役割2011

    • Author(s)
      今泉美佳, 青柳共太, 吉田昌史, 斎藤太郎, 岡村匡史, 竹中均, 中道洋子, 西脇知世乃, 久永真市, 加計正文, 永松信哉
    • Organizer
      第54回日本糖尿病学会年次学術集会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] Acute inhibition of PI3K-PDK1-Akt pathway potentiates glucose-induced insulin secretion in pancreatic b-cells2011

    • Author(s)
      Aoyagi K, Ohara-Imaizumi, M, Nishiwaki C, Nakamichi Y, Nagamatsu S
    • Organizer
      第84回日本生化学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] 糖尿病原因究明のためのイメージングによるインスリン開口放出機構解明2011

    • Author(s)
      今泉美佳, 青柳共太, 永松信哉
    • Organizer
      文部科学省科学研究費補助金「新学術領域研究」第3回細胞内ロジスティクス班会議
    • Place of Presentation
      鳥羽
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] 糖尿病原因究明のためのイメージングによるインスリン開口放出機構解明2011

    • Author(s)
      今泉美佳, 青柳共太, 永松信哉
    • Organizer
      文部科学省科学研究費補助金「新学術領域研究」第3回細胞内ロジスティクス班会議
    • Place of Presentation
      鳥羽
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] ホスファチジルイノシトール3-キナーゼによるインスリン分泌制御機構の可視化解析2010

    • Author(s)
      青柳共太、今泉美佳、西脇知世乃、中道洋子、永松信哉
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] インスリン分泌顆粒細胞内輸送のイメージング:病態との関連2010

    • Author(s)
      今泉美佳、青柳共太、永松信哉
    • Organizer
      第2回細胞内ロジスティクス班会議
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] Insulin/Phosphatidylinositol 3-kinase pathway accelerates the glucose-induced first phase insulin secretion through TrpV2 recruitment in pancreatic beta-cells.2010

    • Author(s)
      青柳共太, 今泉美佳, 永松信哉, (その他2名)
    • Organizer
      第33回日本分子生物学会年会第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] インスリン分泌顆粒細胞内輸送のイメージング:病態との関連2010

    • Author(s)
      今泉美佳、青柳共太、永松信哉
    • Organizer
      第2回 細胞内ロジスティクス班会議(文部科学省科学研究費補助金『新学術領域』)
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] 可視化解析によるインスリン開口放出と糖尿病2010

    • Author(s)
      永松信哉
    • Organizer
      第30回関東腎研究会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-17
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] ホスファチジルイノシトール3-キナーゼによるインスリン分泌制御機構の可視化解析2010

    • Author(s)
      青柳共太、今泉美佳、西脇知世乃、中道洋子、永松信哉
    • Organizer
      第53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] ホスファチジルイノシトール3-キナーゼによるインスリン分泌制御機構の可視化解析2010

    • Author(s)
      青柳共太, 今泉美佳, 永松信哉, (その他2名)
    • Organizer
      53回日本糖尿病学会年次学術集会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] 分泌第2相インスリン開口放出におけるアクチン細胞骨格の調節機構2009

    • Author(s)
      今泉美佳,青柳共太,中道洋子,西脇知世乃,永松信哉
    • Organizer
      第52回日本糖尿病学会年度学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] 分泌第2相インスリン開口放出におけるアクチン細胞骨格の調節機構2009

    • Author(s)
      今泉美佳, 青柳共太, 中道洋子, 西脇知世乃, 永松信哉
    • Organizer
      第52会日本糖尿病学会年度学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] インスリン顆粒の細胞内trafficking2009

    • Author(s)
      今泉美佳, 永松信哉
    • Organizer
      第43回糖尿病学の進歩
    • Place of Presentation
      松本
    • Year and Date
      2009-02-20
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] ミチグリニドおよびグリメピリドを用いた繰り返し刺激に対するインスリン分泌応答の可視化解析.2009

    • Author(s)
      青柳共太, 今泉美佳, 永松信哉, その他2名
    • Organizer
      第52会日本糖尿病学会年度学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] インスリン分泌顆粒細胞内ロジスティックスのイメージング解析2009

    • Author(s)
      今泉美佳, 青柳共太, 佐藤栄人, 永松信哉
    • Organizer
      文部科学省科学研究費補助金・新学術領域「細胞内ロジスティックス」第一回細胞内ロジスティックス班会議
    • Place of Presentation
      沖縄
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] 分泌第2相インスリン開口放出におけるアクチン細胞骨格の調節機構.2009

    • Author(s)
      今泉美佳, 青柳共太, 永松信哉, その他2名
    • Organizer
      第52会日本糖尿病学会年度学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] GLP1顆粒開口放出のイメージング.2009

    • Author(s)
      今泉美佳, 青柳共太, 永松信哉
    • Organizer
      2^<nd> Incretion& Islet Initiative
    • Place of Presentation
      東京
    • Year and Date
      2009-11-28
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] 分泌第2相インスリン開口放出におけるアクチン細胞骨格の調節機構2009

    • Author(s)
      今泉美佳・永松信哉, その他3名
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] 分泌第2相インスリン開口放出におけるアクチン細胞骨格の調節機構2009

    • Author(s)
      今泉美佳, 青柳共太, 中道洋子, 西脇知世乃, 永松信哉
    • Organizer
      第52回日本糖尿病学会年度学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] インスリン顆粒の細胞内traffcking2009

    • Author(s)
      今泉美佳, 永松信哉
    • Organizer
      第43回糖尿病学の進歩
    • Place of Presentation
      松本
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] ミチグリニドおよびグリメピリドを用いた繰り返し刺激に対するインスリン分泌応答の可視化解析2009

    • Author(s)
      青柳共太,今泉美佳,西脇知世乃,中道洋子,永松信哉
    • Organizer
      第52回日本糖尿病学会年度学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] ホルモン分泌動態の可視化2009

    • Author(s)
      永松信哉
    • Organizer
      日本臨床分子医学会学術総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] 肥大化脂肪細胞におけるVEGF120分泌の制御機構について-MCP-1分泌機構との相違-2009

    • Author(s)
      高橋和人, 山口真哉, 下山達宏, 田中利明, 三代川可織, 半田桂子, 勝田秀紀, 西田進, 吉元勝彦, 永松信哉, 石田均
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-19591065
  • [Presentation] インスリン顆粒の細胞内traffcking2009

    • Author(s)
      今泉美佳, 永松信哉
    • Organizer
      第43回糖尿病学の進歩
    • Place of Presentation
      松本
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] ミチグリドおよびグリメピリドを用いた繰り返し刺激に対するインスリン分泌応答の可視化解析2009

    • Author(s)
      青柳共太・永松信哉, その他3名
    • Organizer
      第52回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] ホスファチジルイノシトール-3-キナーゼによるインスリン分泌機構の可視化解析.2009

    • Author(s)
      青柳共太, 今泉美佳, 永松信哉
    • Organizer
      文部科学省科学研究費補助金・新学術領域「細胞内ロジスティックス」第一回細胞内ロジスティックス班会議
    • Place of Presentation
      沖縄
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] GLP1顆粒開口放出のイメージング2009

    • Author(s)
      今泉美佳,青柳共太,永松信哉
    • Organizer
      2^<nd> Incretion&Islet Initiative
    • Place of Presentation
      東京
    • Year and Date
      2009-11-28
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] インスリン顆粒の細胞内trafficking2009

    • Author(s)
      今泉美佳,永松信哉
    • Organizer
      第43回糖尿病学の進歩
    • Place of Presentation
      松本
    • Year and Date
      2009-02-20
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] GLP1顆粒開口放出のイメージング2009

    • Author(s)
      今泉美佳, 青柳共太, 永松信哉
    • Organizer
      2nd Incretion & Islet Initiative
    • Place of Presentation
      東京
    • Year and Date
      2009-11-28
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] インスリン分泌顆粒細胞内ロジスティックスのイメージング解析2009

    • Author(s)
      今泉美佳,青柳共太,佐藤栄人, 永松信哉
    • Organizer
      文部科学省科学研究費補助金・新学術領域「細胞内ロジスティックス」第一回細胞内ロジスティックス班会議
    • Place of Presentation
      沖縄
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] ミチグリニドおよびグリメピリドを用いた繰り返し刺激に対するインスリン分泌応答の可視化解析2009

    • Author(s)
      青柳共太, 今泉美佳, 西脇知世乃, 中道洋子, 永松信哉
    • Organizer
      第52回日本糖尿病学会年度学術集会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] ホスファチジルイノシトール-3-キナーゼによるインスリン分泌機構の可視化解析2009

    • Author(s)
      青柳共太,今泉美佳,永松信哉
    • Organizer
      文部科学省科学研究費補助金・新学術領域「細胞内ロジスティックス」第一回細胞内ロジスティックス班会議
    • Place of Presentation
      沖縄
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] ホスファチジルイノシトール-3-キナーゼによるインスリン分泌機構の可視化解析2009

    • Author(s)
      青柳共太, 今泉美佳, 永松信哉
    • Organizer
      文部科学省科学研究費補助金・新学術領域「細胞内ロジスティックス」第一回細胞内ロジスティックス班会議
    • Place of Presentation
      沖縄
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] インスリン分泌顆粒細胞内ロジスティックスのイメージング解析.2009

    • Author(s)
      今泉美佳, 青柳共太, 永松信哉, その他1名
    • Organizer
      文部科学省科学研究費補助金・新学術領域「細胞内ロジスティックス」第一回細胞内ロジスティックス班会議
    • Place of Presentation
      沖縄
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] ホスファチジルイノシトール3-キナーゼによるインスリン分泌制御機構の可視化解析2008

    • Author(s)
      青柳共太,今泉美佳,西脇知世乃,中道洋子,金子和真,植木浩二郎,門脇孝,永松信哉
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] 膵β細胞における細胞膜直下Ca^<2+>上昇とインスリン顆粒開口放出の関係2008

    • Author(s)
      今泉美佳,青柳共太,中道洋子,西脇知世乃,永松信哉
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] 膵β細胞における細胞膜直下Ca2+上昇とインスリン顆粒開口放出の関係2008

    • Author(s)
      今泉美佳, 青柳共太, 中道洋子, 西脇知世乃, 永松信哉
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] ホスファチジルイノシトール3-キナーゼによるインスリン分泌制御機構の可視化解析.2008

    • Author(s)
      青柳共太, 今泉美佳, 永松信哉, (その他5名)
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] 膵β細胞における細胞膜直下Ca2+上昇とインスリン顆粒開口放出の関係.2008

    • Author(s)
      今泉美佳, 青柳共太, 永松信哉, (その他2名)
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] インスリン分泌機構はどこまで解明されたのか2008

    • Author(s)
      永松信哉, 今泉美佳
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] 膵β細胞における細胞膜直下Ca2+上昇とインスリン顆粒開口放出の関係.2008

    • Author(s)
      今泉美佳, 青柳共太, 永松信哉, (その他2名)
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] Glucolipotoxicityによる膵β細胞からのMCP-1分泌の増加と細胞内情報伝達系の関与2008

    • Author(s)
      関博之, 高橋和人, 三代川可織, 半田桂子, 勝田秀紀, 下山達宏, 田中利明, 山口真哉, 吉元勝彦, 板垣英二, 永松信哉, 石田均
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-19591065
  • [Presentation] (シンポジウム):インスリン分泌機構はどこまで解明されたのか(シンポジウム-20)2008

    • Author(s)
      永松信哉, 今泉美佳
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] インスリン分泌機構はどこまで解明されたのか(シンポジウムー20)2008

    • Author(s)
      永松信哉, 今泉美佳
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] インスリン分泌機構はどこまで解明されたのか(シンポジウムー20)2008

    • Author(s)
      永松信哉, 今泉美佳
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] ホスファチジルイノシトール3-キナーゼによるインスリン分泌制御機構の可視化解析.2008

    • Author(s)
      青柳共太, 今泉美佳, 永松信哉, (その他5名)
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] ホスファチジルイノシトール3-キナーゼによるインスリン分泌制御機構の可視化解析2008

    • Author(s)
      青柳共太, 今泉美佳, 西脇知世乃, 中道洋子, 金子和真, 植木浩二郎, 門脇孝, 永松信哉
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] インスリン第一相、第二相分泌のメカニズムと食後高血糖(食後血糖のグローバルガイドラインとナテグリニド)2008

    • Author(s)
      永松信哉(座談会)
    • Organizer
      EASD2008座談会
    • Place of Presentation
      ローマ
    • Year and Date
      2008-09-08
    • Data Source
      KAKENHI-PROJECT-20390260
  • [Presentation] インスリン分泌機構はどこまで解明されたのか2008

    • Author(s)
      永松信哉,今泉美佳
    • Organizer
      第51回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] Mechanism of insulin granule docking and exocytosis2007

    • Author(s)
      Nagamatsu, S., Ohara-Imaizumi, M.
    • Organizer
      EASD islet study group symposium 2007
    • Place of Presentation
      Brussels,Belgium
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Presentation] Imaging analysis reveals mechanistic differences between first and second phase insulin exocytosis2007

    • Author(s)
      Ohara-Imaizumi, M., Fujiwara, T., Akagawa, K., Nagamatsu, S
    • Organizer
      International Symposium on Membrane Traffic
    • Place of Presentation
      Awaji, Japan
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Presentation] インスリン開口分泌と糖尿病 (糖尿病はどこまでわかったか-原因遺伝子と発症メカニズム-)2007

    • Author(s)
      永松 信哉, 今泉 美佳
    • Organizer
      第27回日本医学会総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-18050033
  • [Presentation] 2型糖尿病におけるインスリン開口放出異常(シンポジウム-5;2型糖尿病の譚β細胞異常(機能・量))2007

    • Author(s)
      永松 信哉, 今泉 美佳
    • Organizer
      第50回日本糖尿病学会年次学術集会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-18050033
  • [Presentation] Mechanism of insulin granule docking and exocytosis, EASD islet study group symposium 20072007

    • Author(s)
      Nagamatsu, S., Ohara-Imaizumi, M
    • Organizer
      Brussels
    • Place of Presentation
      Belgium
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Presentation] Mechanism of insulin g「anule docking and exocytosis2007

    • Author(s)
      Nagamatsu, s., Ohara-Imaizumi, M.
    • Organizer
      EASD islet study group symposium 2007
    • Place of Presentation
      Brussels, Belgium
    • Data Source
      KAKENHI-PROJECT-18050033
  • [Presentation] 分泌第1相と第2相のインスリン開口放出機構は異なっている2007

    • Author(s)
      今泉 美佳, 永松 信教(他4名)
    • Organizer
      第50回日本糖尿病学会年次学術集会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Presentation] Mechanism of insulin granule docking and exocvtosis2007

    • Author(s)
      Nagamatsu, S., Ohara-Imaizumi, M.
    • Organizer
      EASD islet study group symposium 2007
    • Place of Presentation
      Brussels, Belgium
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Presentation] インスリン開口分泌と糖尿病 (糖尿病はどこまでわかったか-原因遺伝子と発症メカニズムー)2007

    • Author(s)
      永松 信哉, 今泉 美佳
    • Organizer
      第27回日本医学会総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Presentation] 2型糖尿病におけるインスリン開口放出異常 (シンポジウムー5;2型糖尿病の膵β細胞異常(機能・量))2007

    • Author(s)
      永松 信哉, 今泉 美佳
    • Organizer
      第50回日本糖尿病学会年次学術集会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Presentation] 分泌第1相と第2相のインスリン開口放出機構は異なっている2007

    • Author(s)
      今泉 美佳, 永松 信哉, (他4名)
    • Organizer
      第50回日本糖尿病学会年次学術集会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-18050033
  • [Presentation] 膵β細胞からのMCP-1分泌に及ぼす高濃度グルコースおよび脂肪酸の影響について2007

    • Author(s)
      関博之, 高橋和人, 伊藤英介, 勝田秀紀, 田中利明, 下山達宏, 山口真哉, 吉元勝彦, 永松信哉, 石田均
    • Organizer
      第50回日本糖尿病学会年次学術集会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-19591065
  • [Presentation] PKC Δ Plays an Essential Role in Glucose Stimulated Insulin Secretion Concurrent with the Enhanced Phosphorylation of Munc18-12006

    • Author(s)
      Uchida, T., Iwashita, N., Ohara-Imaizumi, M, Nagai, S., Choi, J B., Tamura, Y., Nomiyama, T., Ogihara, T., Tada, N., Tanaka, Y., Kawamori, R., Nagamatsu, S., Nakayama, K., Watada, H
    • Organizer
      66th Scientific Session of American Diabetes Association
    • Place of Presentation
      Washinton. DC
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Presentation] Analysis of Newcomer Insulin Secretory Granule Movement by Newly Developed Technique2006

    • Author(s)
      Ohara-Imaizumi, M., Nakamichi, Y., Wakazono, Y., Sakurai, T., Terakawa, S., Nagamatsu, S
    • Organizer
      Variable TIRF Real-Time Imaging System 66th Scientific Session of American Diabetes Association
    • Place of Presentation
      Washinton. DC
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Presentation] Analysis of Newcomer Insulin Secretory Granule Movement by Newl y Developed Technique, Variable TIRF Real-Time Imaging System2006

    • Author(s)
      Ohara-Imaizumi M, , Nagamatsu S.(他4名)
    • Organizer
      66th Scientific Session of American Diabetes As sociation
    • Place of Presentation
      Washinton.DC USA
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Presentation] Adiponectin Stimulates Insulin Secretion In Vitro and In Vivo2006

    • Author(s)
      Hashimoto, S., Okamoto, M., Kubota, N., Ohara-Imaizumi, M, Eto, K., Takamoto, I., Yamaguchi, T., Ueki, K., Terauchi, Y., Nagamatsu, S., Kadowaki, T
    • Organizer
      66th Scientific Session of American Diabetes Association
    • Place of Presentation
      Washinton. DC
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Presentation] Visualized action of hypoglycemic agents,glinide and sulphonylurea,on the dynamic motion of insulin secretory granules analyzed by TIR F imaeine2005

    • Author(s)
      Ohara-Imaizumi M., Nagamatsu S.(他3名)
    • Organizer
      65th Scientific Session of American Diabetes As sociation
    • Place of Presentation
      San Diego Jun.USA
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Presentation] Visualized action of hypoglycemic agents, glinide and sulphonylurea, on the dynamic motion of insulin secretory granules analyzed by TIRF imaging2005

    • Author(s)
      Ohara-Imaizumi, M, Kikuta, T, Nishiwaki, C, Nakamichi, Y, Nagamatsu, S
    • Organizer
      65th Scientific Session of American Diabetes Association
    • Place of Presentation
      San Diego
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Presentation] TIRF imaging analysis of the dynamic motion of insulin granules by antidiabetic agents2005

    • Author(s)
      Shinya Nagamatsu, Ohara-Imaiz umi M.
    • Organizer
      1st Scientific Meeting of the Asia-Pacific Diabetes and Obesity Study Group
    • Place of Presentation
      Kobe
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Presentation] Rab3 and SNAP25 in Islets are increased in insulin-resistant Irs2-/-mice and markedly decreased in.severely-hyperglycemic Irs2-/- mice on a high fat diet2005

    • Author(s)
      Suzuki R., Ohara-Imaizumi M., Nagamatsu S.(他8名)
    • Organizer
      65th Scientific Session of American Diabetes As sociation
    • Place of Presentation
      San Diego Jun.USA
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Presentation] ELKS, a protein structurally related to the active zone associated protein CAST2005

    • Author(s)
      Ohara-Imaizumi, M, Ohtsuka, T, Matsushima, S, Akimoto, Y, Nishiwaki, C, Nakamichi, Y, Kikuta, T, Nagai, S, Kawakami, H, Watanabe, T, Nagamatsu, S
    • Organizer
      is expressed in pancreatic beta cells and functions in insulin exocytosis 41st Annual Meeting of the EASD
    • Place of Presentation
      Athens, Greece
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Presentation] ELKS,a protein structurally related to the active zone associated protein CAST, is expressed in pancreatic beta cells and functions in insul in exocytosis2005

    • Author(s)
      Ohara-Imaizumi M, , Nagamatsu S.(他9名)
    • Organizer
      41st Annual Meeting of the EASD
    • Place of Presentation
      Athens,Greece
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590277
  • [Presentation] 第2相インスリン分泌制御におけるPI-3 kinaseとPDK1-Akt経路の役割の検討

    • Author(s)
      青柳共太、今泉美佳、永松信哉
    • Organizer
      第16回東京インスリン分泌研究会
    • Place of Presentation
      2012年2月23日
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] Insulin/Phosphatidylinositol 3-kinase pathway accelerates the glucose-induced first phase insulin secretion through TrpV2 recruitment in pancreatic beta-cells.

    • Author(s)
      青柳共太、今泉美佳、西脇知世乃、中道洋子、永松信哉
    • Organizer
      第33回日本分子生物学会年会第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20570189
  • [Presentation] Functional Role of Serotonin in Insulin Secretion Under Diet-induced Insulin-Resistant State

    • Author(s)
      Kim K, Oh C-M, Ohara-Imaizumi, M, Nagamatsu S, German MS, Kim H.
    • Organizer
      74th Scientific Session of American Diabetes Association
    • Place of Presentation
      San Francisco, CA, USA
    • Year and Date
      2014-06-13 – 2014-06-17
    • Data Source
      KAKENHI-PROJECT-26460396
  • [Presentation] ノックアウトマウスを用いたインスリン開口分泌のイメージング解析「シンポジウム:モデル動物を用いたインスリン分泌研究」

    • Author(s)
      今泉美佳、青柳共太、岸本拓磨、永松信哉
    • Organizer
      第29回日本糖尿病・肥満動物学会年次学術集会
    • Place of Presentation
      京都
    • Year and Date
      2015-02-13 – 2015-02-14
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460396
  • [Presentation] 糖尿病原因究明のためのイメージングによるインスリン開口放出機構解明

    • Author(s)
      今泉美佳, 青柳共太, 永松信哉
    • Organizer
      文部科学省 科学研究費補助金「新学術領域研究」第3回 細胞内ロジスティクス班会議
    • Place of Presentation
      2011年6月1日~3日
    • Data Source
      KAKENHI-PROJECT-23590369
  • [Presentation] CDKAL1欠損マウスでは妊娠期の代償性インスリン分泌亢進機能が低下している

    • Author(s)
      今泉美佳,青柳共太,岡村匡史,中道洋子,西脇知世乃,永松信哉
    • Organizer
      第57回日本糖尿病学会年次学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-05-22 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-26460396
  • [Presentation] 有芯顆粒を介したインスリン分泌動態の可視化 (シンポジウム:神経ペプチドや神経栄養因子の小胞輸送と精神神経疾患)

    • Author(s)
      今泉美佳、青柳共太、岸本拓磨、永松信哉
    • Organizer
      第36回日本生物学的精神医学会・第57回日本神経化学会大会合同年会
    • Place of Presentation
      奈良
    • Year and Date
      2014-09-29 – 2014-10-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-26460396
  • [Presentation] Insulin/Phosphatidylinositol 3-kinase pathway accelerates the secretion through TrpV2 recruitment in pancreatic beta-cells

    • Author(s)
      青柳共太、今泉美佳、西脇知世乃、中道洋子、永松信哉
    • Organizer
      第33回日本分子生物学会年会第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20390260
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  • 12.  MAEDA Tatsuhiro (50210993)
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  • 13.  ABE Nobutsugu (40266747)
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  • 14.  SASAKI Hideo (60333027)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 15.  INUKAI Kouichi (20333007)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  TAKEUCHI Kazuo (80086462)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  HIRAKATA Akito (80173219)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  SASAKAWA Nobuyuki (20187107)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  KUMAKURA Konosuke (70129790)
    # of Collaborated Projects: 1 results
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  • 20.  中村 幸雄 (60051512)
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    # of Collaborated Products: 0 results
  • 21.  吉村 泰典 (10129736)
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    # of Collaborated Products: 0 results
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    # of Collaborated Products: 0 results
  • 23.  小松 明男 (20225569)
    # of Collaborated Projects: 1 results
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  • 24.  内ケ崎 新也 (80146547)
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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