SASAKI KAZUKI 佐々木一樹

… Alternative Names

佐々木一樹ササキカズキ

SASAKI Kazuki 佐々木一樹

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Researcher Number	80260313
Other IDs
Affiliation (Current)	2025: 地方独立行政法人栃木県立がんセンター(研究所), 研究所－腫瘍ペプチドミクスプロジェクト, プロジェクトリーダー 2025: 地方独立行政法人栃木県立がんセンター(研究所), 研究所－医療シーズ探索G－腫瘍プロテオゲノミクス研究分野, 主任研究員 2025: 公益財団法人佐々木研究所, 附属研究所, 研究員
Affiliation (based on the past Project Information) *help	2023: 公益財団法人佐々木研究所, 附属研究所, 研究員(移行) 2018: 公益財団法人佐々木研究所, 附属研究所, 部長(移行) 2015 – 2017: 国立研究開発法人国立循環器病研究センター, 研究所, 室長 2012 – 2014: 独立行政法人国立循環器病研究センター, 研究所, 室長 2010 – 2011: 独立行政法人国立循環器病研究センター, 分子薬理部, 室長 … More 2008: 国立循環器病センター(研究所), 薬理部, 部長 2007 – 2008: 国立循環器病センター(研究所), 薬理部, 室長 2006: 国立循環器病センター研究所, 薬理部, 室長 2003: 国立がんセンター研究所, 細胞増殖因子研究部, 室長 Less
Review Section/Research Field	Principal Investigator Endocrinology / Gastroenterology / Biological Sciences Except Principal Investigator Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Living organism molecular science / Applied genomics
Keywords	Principal Investigator 質量分析 / ペプチドミクス / ペプチド / 生理活性ペプチド / 膵臓学 / タンパク質切断 / 限定分解 / 膵腺癌 / mass spectrometry / insulin … More / peptidomics / peptides / プロセシング / 内分泌腫瘍 / 分泌顆粒 / 視床下部 / 神経内分泌腫瘍 / 内分泌学 / 腫瘍マーカー … More Except Principal Investigator 分解ペプチド / 生理活性ペプチド / ペプチド / 質量分析 / プロセシング / ゲノム異常 / がん間質細胞 / 細胞分裂 / GMN癌細胞 / 巨多核癌細胞 / GMN / 組織ペプチドーム解析 / 分解ペプチド標識法 / 標識法 / 内在ペプチド / ペプチドーム解析 / データベース / 副腎髄質 / カルシトニン遺伝子関連ペプチド / カルシトニン / 甲状腺C細胞 / 下垂体 / ペプチドーム Less

GMN癌細胞の生存戦略とゲノム変異の多様性に基づく再燃・転移の治療開発
- Principal Investigator
  
  田中正光
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Akita University
Peptidomics for studying limited proteolysis in pancreatic cancerPrincipal Investigator
- Principal Investigator
  
  Sasaki Kazuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Sasaki Foundation
  National Cardiovascular Center Research Institute
Peptidomics for studying biological functions of VGFPrincipal Investigator
- Principal Investigator
  
  Sasaki Kazuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  National Cardiovascular Center Research Institute
Development of tissue peptidome analysis technology and its application to discovery of new biologically active peptides
- Principal Investigator
  
  MINAMINO Naoto
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Living organism molecular science
- Research Institution
  National Cardiovascular Center Research Institute
Snapshot peptidomics for bioactive peptide discoveryPrincipal Investigator
- Principal Investigator
  
  SASAKI Kazuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  National Cardiovascular Center Research Institute
Tissue-specific processing pathway of precursor proteins deduced from peptidome analysis
- Principal Investigator
  
  MINAMINO Naoto
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied genomics
- Research Institution
  National Cardiovascular Center Research Institute
血液からのペプチド性腫瘍マーカー探索法の確立Principal Investigator
- Principal Investigator
  
  佐々木一樹
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East

[Book] Peptidomics strategy for discovering endogenous peptides. (Kastin A ed. In Handbook of Biologically Active Peptides 2^<nd> ed.)2013
- Author(s)
  Sasaki K and Minamino N.
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-22591023
[Book] Peptidomics strategy for discovering endogenous biologically active peptides2013
- Author(s)
  Sasaki K, Minamino, N
- Publisher
  Academic Press/Elsevier
- Data Source
  KAKENHI-PROJECT-23310155
[Book] Handbook of the Biologically Active Peptides, Second Edition2013
- Author(s)
  Sasaki K, Minamino N.
- Total Pages
  8
- Publisher
  Academic Press/Elsevier
- Data Source
  KAKENHI-PROJECT-23310155
[Book] Handbook of Biologically Active Peptides (Second Edition)2013
- Author(s)
  Kazuki Sasaki
- Total Pages
  8
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-22591023
[Book] Mass Spectrometry-based Peptidomics for the Discovery of Antimicrobial Peptides2013
- Author(s)
  Tsukasa Osaki, Kazuki Sasaki and Naoto Minamino
- Total Pages
  9
- Publisher
  Formatex Research Center
- Data Source
  KAKENHI-PROJECT-25461402
[Book] ペプチド医薬の最前線2012
- Author(s)
  佐々木一樹
- Total Pages
  4
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-22591023
[Book] ペプチドミクを活用する生理活性ペプチドの探索. ファインケミカルシリーズペプチド医薬の最前線(木曽良明、向井秀仁編)2012
- Author(s)
  佐々木一樹、尾崎司、南野直人
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-22591023
[Book] ペプチドミクスを活用する新規生理活性ペプチドの探索、ペプチド医薬の最前線2012
- Author(s)
  佐々木一樹
- Total Pages
  4
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-23310155
[Book] ペプチドミクスを活用する新規生理活性ペプチドの探索2012
- Author(s)
  佐々木一樹, 尾崎司, 南野直人
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-23310155
[Book] セクレトペプチドーム解析で発見された新しい摂食調節ペプチド NERP-2、実験医学増刊「代謝・内分泌ネットワークと医薬応用」(児島将康、斎藤祐見子、中里雅光編)2011
- Author(s)
  佐々木一樹、山口秀樹、中里雅光、南野直人
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22591023
[Book] 質量分析法を活用する生理活性ペプチドの探索- Neuroendocrine Regulatory Peptides の発見2011
- Author(s)
  佐々木一樹, 山口秀樹, 中里雅光, 南野直人
- Publisher
  日本臨床化学会
- Data Source
  KAKENHI-PROJECT-23310155
[Book] 質量分析法を活用する生理活性ペプチドの探索-Neuroendocrine Regulatory Peptidesの発見、臨床化学 10巻2号2011
- Author(s)
  佐々木一樹、山口秀樹、中里雅光、南野直人
- Data Source
  KAKENHI-PROJECT-22591023
[Book] 生理活性ペプチド探索のためのペプチドミクス、実験医学増刊「創薬・タンパク質研究のためのプロテオミクス解析」(小田吉哉、長野光司編)2010
- Author(s)
  佐々木一樹、南野直人
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-22591023
[Book] Secretopeptidome mining for novel bioactive peptides. Peptide Science, Vol.20092010
- Author(s)
  Osaki T, Sasaki K, Minamino N.
- Data Source
  KAKENHI-PROJECT-22591023
[Book] 循環器科(ペプチドーム解析とNERPの発見)2008
- Author(s)
  南野直人, 佐々木一樹
- Data Source
  KAKENHI-PROJECT-18310138
[Book] 生理活性ペプチド探索のためのペプチドミクス研究、ペプチドと創薬 (寒川賢治、南野直人(編))2007
- Author(s)
  佐々木一樹, 南野直人
- Publisher
  Medical Do
- Data Source
  KAKENHI-PROJECT-18310138
[Book] 生理活性ペプチド探索のためのペプチドミクス研究ペプチドと創薬(寒川賢治、南野直人編)2007
- Author(s)
  佐々木一樹, 南野直人
- Total Pages
  6
- Publisher
  Medical Do社
- Data Source
  KAKENHI-PROJECT-18310138
[Journal Article] Isolation of Endogenous Peptides from Cultured Cell Conditioned Media for Mass Spectrometry2018
- Author(s)
  Sasaki Kazuki、Tsuchiya Takashi、Osaki Tsukasa
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 1719 Pages: 51-58
- DOI
  10.1007/978-1-4939-7537-2_3
- ISBN
  9781493975365, 9781493975372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09404
[Journal Article] Endogenous peptide profile for elucidating biosynthetic processing of the ghrelin precursor2017
- Author(s)
  Tsuchiya Takashi、Iwakura Hiroshi、Minamino Naoto、Kangawa Kenji、Sasaki Kazuki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 490 Issue: 4 Pages: 1142-1146
- DOI
  10.1016/j.bbrc.2017.06.155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09404
[Journal Article] NERP-2 regulates gastric acid secretion and gastric emptying via the orexin pathway.2017
- Author(s)
  Cherl Namkoong, Koji Toshinai, Zaved Waise, Hideyuki Sakoda, Kazuki Sasaki, Yoichi Ueta, Min-Seon Kim, Naoto Minamino, Masamitsu Nakazato.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 485 Issue: 2 Pages: 409-413
- DOI
  10.1016/j.bbrc.2017.02.064
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05333, KAKENHI-PROJECT-26560368, KAKENHI-PROJECT-16K09404, KAKENHI-PROJECT-16K09761
[Journal Article] ペプチドミクスを活用した生理活性ペプチドの発見2017
- Author(s)
  佐々木一樹
- Journal Title
  
  生化学
  
  Volume: 89 Pages: 894898-894898
- NAID
  40021439312
- Data Source
  KAKENHI-PROJECT-16K09404
[Journal Article] Characterization of gonadotrope secretoproteome identifies neurosecretory protein VGF-derived peptide suppression of follicle-stimulating hormone gene expression2016
- Author(s)
  Choi SG, Wang Q, Jia J, Chikina M, Pincas H, Dolios G, Sasaki K, Wang R, Minamino N, Salton SR, Sealfon SC
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 291 Pages: 2132221334-2132221334
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09404
[Journal Article] Chronic effects of neuroendocrine regulatory peptide (NERP-1 and -2) on insulin secretion and gene expression in pancreatic beta-cells.2015
- Author(s)
  Kim JW, Rhee M, Park JH, Yamaguchi H, Sasaki K, Minamino N, Nakazato M, Song DK, Yoon KH
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 457 Issue: 2 Pages: 148-153
- DOI
  10.1016/j.bbrc.2014.12.067
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22126009, KAKENHI-PROJECT-25461402, KAKENHI-PROJECT-25293216
[Journal Article] Peptidomics for Studying Limited Proteolysis2015
- Author(s)
  Takashi Tsuchiya, Tsukasa Osaki, Naoto Minamino, Kazuki Sasaki
- Journal Title
  
  Journal of Proteome Research
  
  Volume: 14 Issue: 11 Pages: 4921-4931
- DOI
  10.1021/acs.jproteome.5b00820
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461402
[Journal Article] Region-specific activation of CRTC1-CREB signaling mediates long-term fear memory2014
- Author(s)
  Nonaka M, Kim R, Fukushima H, Sasaki K, Suzuki K, Okamura M, Ishii Y, Kawashima T, Kamijo S, Takemoto-Kimura S, Okuno H, Kida S, Bito H
- Journal Title
  
  Neuron
  
  Volume: 84 Issue: 1 Pages: 92-106
- DOI
  10.1016/j.neuron.2014.08.049
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23680040, KAKENHI-ORGANIZER-24116001, KAKENHI-PLANNED-24116008, KAKENHI-PROJECT-24300117, KAKENHI-PUBLICLY-25116507, KAKENHI-PROJECT-25461402, KAKENHI-PUBLICLY-26115507, KAKENHI-PROJECT-26640014
[Journal Article] ペプチドミクス―内因性分泌ペプチドの一斉解析から新規生理活性ペプチドの発見へ2014
- Author(s)
  佐々木一樹
- Journal Title
  
  医学のあゆみ
  
  Volume: 251 Pages: 1017-1021
- Data Source
  KAKENHI-PROJECT-25461402
[Journal Article] Neuroendocrine regulatory peptide-1 and -2 (NERPs) inhibit the excitability of magnocellular neurosecretory cells in the hypothalamus.2014
- Author(s)
  Toshinai K, Saito T, Yamaguchi H, Sasaki K, Tsuchimochi W, Minamino N, Ueta Y, Nakazato M
- Journal Title
  
  Brain Res
  
  Volume: 1563 Pages: 52-60
- DOI
  10.1016/j.brainres.2014.03.038
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22126009, KAKENHI-PROJECT-23591358, KAKENHI-PROJECT-25293216, KAKENHI-PROJECT-25461402, KAKENHI-PROJECT-26560368
[Journal Article] Flotillin-1 regulates oncogenic signaling in neuroblastoma cells by regulating ALK membrane association.2014
- Author(s)
  Tomiyama A, Uekita T, Kamata R, Sasaki K, Takita J, Ohira M, Nakagawara A, Kitanaka C, Mori K, Yamaguchi H, Sakai R.
- Journal Title
  
  Cancer Res.
  
  Volume: 74(14) Issue: 14 Pages: 3790-3801
- DOI
  10.1158/0008-5472.can-14-0241
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249061, KAKENHI-PROJECT-24501327, KAKENHI-PROJECT-25253095, KAKENHI-PROJECT-25430126, KAKENHI-PROJECT-25461402, KAKENHI-PROJECT-26290043, KAKENHI-PROJECT-26293242, KAKENHI-PROJECT-26461603, KAKENHI-PROJECT-26670493
[Journal Article] The src substrate SKAP2 regulates actin assembly by interacting with WAVE2 and cortactin proteins.2013
- Author(s)
  Shimamura S, Sasaki K, Tanaka M.
- Journal Title
  
  J Biol Chem.
  
  Volume: 288 Pages: 1171-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591023
[Journal Article] Continuous stress promotes expression of VGF in melanotroph via suppression of dopamine2013
- Author(s)
  Kyohei Tokizane
- Journal Title
  
  Molecular and Cellular Endocrinology
  
  Volume: 372 Issue: 1-2 Pages: 4956-4956
- DOI
  10.1016/j.mce.2013.03.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591023, KAKENHI-PROJECT-23310155, KAKENHI-PROJECT-23590240, KAKENHI-PROJECT-25461402, KAKENHI-PROJECT-25670093, KAKENHI-PROJECT-25830050
[Journal Article] Large-scale identification of endogenous secretory peptides using electron transfer dissociation mass spectrometry2013
- Author(s)
  Sasaki K, Osaki T, Minamino N
- Journal Title
  
  Mol Cell Proteomics
  
  Volume: 12 Pages: 700-709
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310155
[Journal Article] Continuous stress promotes expression of VGF in melanotroph via suppression of dopamine2013
- Author(s)
  Tokizane K, Sasaki K, Minamino N, Kiyama H, 他3名
- Journal Title
  
  Mol Cell Endocrinol
  
  Volume: 372 Pages: 49-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310155
[Journal Article] Large-scale identification of endogenous secretory peptides using electron transfer dissociation mass spectrometry2013
- Author(s)
  Kazuki Sasaki
- Journal Title
  
  Molecular and Cellular Proteomics
  
  Volume: 12 Issue: 3 Pages: 700709-700709
- DOI
  10.1074/mcp.m112.017400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591023
[Journal Article] Continuous stress promotes expression of VGF in melanotroph via suppression of dopamine.2013
- Author(s)
  Tokizane K, Konishi H, Yasui M, Ogawa T, Sasaki K, Minamino N, Kiyama H.
- Journal Title
  
  Mol Cell Endocrinol.
  
  Volume: 372 Pages: 49-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591023
[Journal Article] Large-scale identification of endogenous secretory peptides using electron transfer dissociation mass spectrometry.2013
- Author(s)
  Sasaki K, Osaki T, Minamino N.
- Journal Title
  
  Mol Cell Proteomics
  
  Volume: 12 Pages: 700-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591023
[Journal Article] Neuroendocrine regulatory peptide-2 stimulates glucose-induced insulin secretion in vivo and in vitro2012
- Author(s)
  Moin AS, Yamaguchi H, Sasaki K, Minamino N, 他8名
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 428 Pages: 512-517
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310155
[Journal Article] Neuroendocrine regulatory peptide-2 stimulates glucose-induced insulin secretion in vivo and in vitro.2012
- Author(s)
  Moin AS, Yamaguchi H, Rhee M, Kim JW, Toshinai K, Zaved Waise TM, Kaznin F, Matsuo T, Sasaki K, Minamino N, Yoon KH, Nakazato M.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 428 Pages: 512-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591023
[Journal Article] Molecular characterization and biological function of neuroendocrine regulatory peptide-3 in the rat.2012
- Author(s)
  Fujihara H, Sasaki K, Mishiro-Sato E, Ohbuchi T, Dayanithi G, Yamasaki M, Ueta Y, Minamino N.
- Journal Title
  
  Endocrinology
  
  Volume: 153 Pages: 1377-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591023
[Journal Article] Molecular characterization and biological function of neuroendocrine regulatory peptide-3 in the rat2012
- Author(s)
  Fujihara H, Sasaki K, Ueta Y, Minamino N, 他4名
- Journal Title
  
  Endocrinology
  
  Volume: 153 Pages: 1377-1386
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310155
[Journal Article] ARAP3 inhibits peritoneal dissemination of scirrhous gastric carcinoma cells by regulating cell adhesion and invasion.2011
- Author(s)
  Yagi R, Tanaka M, Sasaki K, Kamata R, Nakanishi Y, Kanai Y, Sakai R.
- Journal Title
  
  Oncogene
  
  Volume: 30 Pages: 1413-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591023
[Journal Article] Peptidomics-based discovery of an antimicrobial peptide derived from insulin-like growth factor-binding protein 52011
- Author(s)
  T.Osaki, K.Sasaki, N.Minamino
- Journal Title
  
  Journal of Proteome Research
  
  Volume: 10 Issue: 4 Pages: 1870-1880
- DOI
  10.1021/pr101114a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310155
[Journal Article] Peptidomics-based discovery of an antimicrobial peptide derived from insulinlike growth factor-binding protein 52011
- Author(s)
  Osaki T, Sasaki K, Minamino N
- Journal Title
  
  J Proteome Res
  
  Volume: 10 Pages: 1870-1880
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310155
[Journal Article] Peptidomicsbased discovery of an anti-microbial peptide derived from insulin-like growth factorbinding protein 5.2011
- Author(s)
  Osaki T, Sasaki K, Minamino N.
- Journal Title
  
  J Proteome Res.
  
  Volume: 10 Pages: 1870-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591023
[Journal Article] Neuroendocrine regulatory peptide-2 regulates feeding behavior via the orexin system in the hypothalamus.2010
- Author(s)
  Toshinai K, Yamaguchi H, Kageyama H, Matsuo T, Koshinaka K, Sasaki K, Shioda S, Minamino N, Nakazato M.
- Journal Title
  
  Am J Physiol Endocrinol Metab.
  
  Volume: 299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591023
[Journal Article] Characterization of the testisspecific promoter region in the human pituitary adenylate cyclase-activating polypeptide (PACAP) gene.2010
- Author(s)
  Tominaga A, Sugawara H, Futagawa T, Inoue K, Sasaki K, Minamino N, Hatakeyama M, Handa H, Miyata A.
- Journal Title
  
  Genes Cells.
  
  Volume: 15 Pages: 595-606
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591023
[Journal Article] A Peptidomics Strategy for discovering endogenous bioactive peptides.2010
- Author(s)
  Sasaki K, Takahashi N, Satoh M, Yamasaki M, Minamino N.
- Journal Title
  
  J Proteome Res.
  
  Volume: 9 Pages: 5047-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591023
[Journal Article] A peptidomics strategy for discovering endogenous bioactive peptides.2010
- Author(s)
  Kazuki Sasaki
- Journal Title
  
  Journal of Proteome Research
  
  Volume: 9 Pages: 5047-5052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591023
[Journal Article] [Epub ahead of print] Neuroendocrine regulatory peptide-2 regulates feeding behavior via the orexin system in the hypothalamus2010
- Author(s)
  K. Toshinai, H. Yamaguchi, H. Kageyama, T. Matsuo, K. Koshinaka, K. Sasaki, S. Shioda, N. Minamino, M. Nakazato
- Journal Title
  
  Am J Physiol Endocrinol Metab
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310138
[Journal Article] [Epub ahead of print] Localization of neuroendocrine regulatory peptide-1 and -2 in human tissues2010
- Author(s)
  T. Matsuo, H. Yamaguchi, H. Kageyama, K. Sasaki, S. Shioda, N. Minamino, M. Nakazato
- Journal Title
  
  Regul. Pept.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310138
[Journal Article] Localization of neuroendocrine regulatory peptide-1 and-2 in human tissues.2010
- Author(s)
  Matsuo T, Yamaguchi H, Kageyama H, Sasaki K, Shioda S, Minamino N, Nakazato M.
- Journal Title
  
  Regul Pept.
  
  Volume: 163 Pages: 43-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591023
[Journal Article] Distribution of neuroendocrine regulatory peptide-1 and -2, and proteolytic processing of their precursor VGF protein in the rat.2010
- Author(s)
  E. Mishiro-Satoh, K. Sasaki, T. Matsuo, H. Kageyama, H. Yamaguchi, Y. Date, M. Matsubara, T. Ishizu, K. Yoshizawa-Kumagaye, Y. Satomi, T. Takao, S. Shioda, M. Nakazato, N. Minamino
- Journal Title
  
  J. Neurochem 114
  
  Pages: 1097-1106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310138
[Journal Article] Distribution of neuroendocrine regulatory peptide-1 and -2, and proteolytic processing of their precursor VGF protein in the rat.2010
- Author(s)
  Mishiro-Sato E, Sasaki K, Matsuo T, Kageyama H, Yamaguchi H, Date Y, Matsubara M, Ishizu T, Yoshizawa-Kumagaye K, Satomi Y, Takao T, Shioda S, Nakazato M, Minamino N.
- Journal Title
  
  J Neurochem
  
  Volume: 114 Pages: 1097-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591023
[Journal Article] Snapshot peptidomics of the regulated secretory pathway2009
- Author(s)
  K. Sasaki, Y. Satomi, T. Takao, N. Minamino
- Journal Title
  
  Mol. Cell. Proteomics 8
  
  Pages: 1638-1647
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310138
[Journal Article] Natriuretic peptides in Cetaceans: Identification, molecular characterization and changes in plasma concentration after landing2007
- Author(s)
  T. Naka, K. Sasaki, N. Minamino
- Journal Title
  
  Zool. Sci. 24
  
  Pages: 577-587
- NAID
  40015552143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310138
[Journal Article] Peptidomic identification and biological validation of neuroendocrine regulatory peptide-1 and -22007
- Author(s)
  H. Yamaguchi, K. Sasaki, N. Minamino
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 26354-26360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310138
[Journal Article] Peptidomic identification and biological validation of neuroendocrine regulatory peptide-1 and -2. *: equally contributed2007
- Author(s)
  H. Yamaguchi*, K. Sasaki*, Y. Satomi*, T. Shimbara, H. Kageyama, M. S. Mondal, K. Toshinai, Y. Date, L. J. Gonzalez, S. Shioda, T. Takao, M, Nakazato, N. Minamino
- Journal Title
  
  J. Biol. Chem 282
  
  Pages: 26354-26360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310138
[Journal Article] Natriuretic peptides in Cetaceans : Identification, molecular characterization and changes in plasma concentration after landing2007
- Author(s)
  T. Naka, E. Katsumata, K. Sasaki, N. Minamino, M. Yoshioka, Y. Takei
- Journal Title
  
  Zool. Sci. 24
  
  Pages: 577-587
- NAID
  40015552143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310138
[Journal Article] Snapshot peptidomics of the regulated secretory pathway
- Author(s)
  Sasaki K, Satomi Y, Takao T, Minamino N.
- Journal Title
  
  Mol. Cell. Proteomics (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18310138
[Patent] ペプチド及びその用途2012
- Inventor(s)
  南祇利実、南野直人、佐々木一樹、尾崎司
- Industrial Property Rights Holder
  武田薬品工業株式会社、独立行政法人国立循環器病研究センター
- Acquisition Date
  2012-09-06
- Overseas
- Data Source
  KAKENHI-PROJECT-22591023
[Patent] 生理活性ペプチド及びその用途2012
- Inventor(s)
  山崎基生、高橋憲行、南野直人、佐々木一樹
- Industrial Property Rights Holder
  協和発酵キリン株式会社、独立行政法人国立循環器病研究センター
- Acquisition Date
  2012-04-19
- Overseas
- Data Source
  KAKENHI-PROJECT-22591023
[Patent] ペプチドおよびその用途2010
- Inventor(s)
  佐々木一樹, 外3名
- Industrial Property Rights Holder
  国立循環器病研究センター
- Acquisition Date
  2010-12-23
- Data Source
  KAKENHI-PROJECT-22591023
[Patent] 生理活性ペプチド及びその用途2010
- Inventor(s)
  佐々木一樹, 外3名
- Industrial Property Rights Holder
  国立循環器病研究センター
- Industrial Property Number
  2010-225276
- Filing Date
  2010-10-04
- Data Source
  KAKENHI-PROJECT-22591023
[Patent] 生理活性ペプチドおよびその用途2010
- Inventor(s)
  佐々木一樹外3名
- Industrial Property Rights Holder
  国立循環器病研究センター外1法人
- Industrial Property Rights Type
  特許
- Filing Date
  2010-10-04
- Acquisition Date
  2012-04-19
- Data Source
  KAKENHI-PROJECT-22591023
[Patent] ペプチドおよびその用途2010
- Inventor(s)
  佐々木一樹, 外3名
- Industrial Property Rights Holder
  国立循環器病研究センター
- Acquisition Date
  2010-12-23
- Overseas
- Data Source
  KAKENHI-PROJECT-22591023
[Patent] 新規生理活性ペプチド2007
- Inventor(s)
  南野直人, 佐々木一樹, 高尾敏文, 里見佳典, 山崎基生, 高橋憲行
- Industrial Property Rights Holder
  協和発酵工業株式会社、国立循環器病センター、国立大学法人大阪大学
- Industrial Property Number
  2007-014455
- Filing Date
  2007-01-25
- Data Source
  KAKENHI-PROJECT-18310138
[Presentation] Endogenous Peptide Profiling for Studying Limited Proteolysis2017
- Author(s)
  Kazuki Sasaki
- Organizer
  PepCon2017
- Place of Presentation
  福岡
- Year and Date
  2017-03-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09404
[Presentation] Peptidomics for naturally occurring secretory peptides using electron transfer dissociation (ETD) mass spectrometry2013
- Author(s)
  Sasaki K, Osaki T, Minamino N.
- Organizer
  12th HUPO World Congress
- Place of Presentation
  横浜、パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23310155
[Presentation] Proteomic analysis of left ventricular tissues in dilated cardiomyopathy mouse models2013
- Author(s)
  Nishigori M, Yagi H, Mochizuki A, Sasaki K, Iwata Y, Wakabayashi S, Minamino N.
- Organizer
  12th HUPO World Congress
- Place of Presentation
  横浜、パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23310155
[Presentation] Peptidomics for naturally occurring secretory peptides using electron transfer dissociation (ETD) mass spectrometry2013
- Author(s)
  Sasaki K, Osaki T, Minamino N
- Organizer
  12th HUPO World Congress
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23310155
[Presentation] オミックス解析技術を用いた新規血管作動性ペプチド、タンパク質の探索2013
- Author(s)
  南野直人、尾崎司、八木寛陽、錦織充広、高山健太郎、佐々木一樹
- Organizer
  第36回日本高血圧学術総会シンポジウム「血管作動性物質研究の最前線」
- Place of Presentation
  大阪、大阪国際会議場
- Invited
- Data Source
  KAKENHI-PROJECT-23310155
[Presentation] Peptidomic survey of peptides found in culture supernatant of cardiac fibroblast -an expanded application to common cell having the constitutive secretory pathway2013
- Author(s)
  Tsuchiya T, Sasaki K, Osaki T, Minamino N
- Organizer
  4th Asia Pacific International Peptide Symposium
- Place of Presentation
  ホテル阪急エキスポパーク,大阪
- Data Source
  KAKENHI-PROJECT-23310155
[Presentation] VGF-derived peptides identified by mass spectrometry and their functions2012
- Author(s)
  佐々木一樹
- Organizer
  The 3rd meeting of the Japan Branch of the International Neuropeptide Societｙ
- Place of Presentation
  小倉、北九州国際カンファレンスセンター
- Invited
- Data Source
  KAKENHI-PROJECT-23310155
[Presentation] ラット脳内におけるNERP 類の分布,局在とバソプレシン分泌に及ぼす効果2012
- Author(s)
  望月明和, 佐々木一樹, 中里雅光, 上田陽一, 塩田清二, 南野直人
- Organizer
  第16回日本心血管内分泌代謝学会学術総会
- Place of Presentation
  東京大学
- Data Source
  KAKENHI-PROJECT-23310155
[Presentation] VGFderived peptides identified by mass spectrometry and their functions2012
- Author(s)
  Sasaki K, Ueta Y, Minamino N
- Organizer
  3rd Meeting of Japan Branch of the International Neuropeptide Society
- Place of Presentation
  北九州コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23310155
[Presentation] Secretopeptidome and discovery of new biologically active peptides2011
- Author(s)
  Minamino N, Osaki T, Sasaki K
- Organizer
  9th Australian Peptide Conference
- Place of Presentation
  Hamilton Island, Australia
- Data Source
  KAKENHI-PROJECT-23310155
[Presentation] ペプチドミクスのための質量分析2011
- Author(s)
  佐々木一樹
- Organizer
  日本生化学会
- Year and Date
  2011-09-22
- Data Source
  KAKENHI-PROJECT-22591023
[Presentation] Peptidomics-based discovery of an antimicrobial peptide derived from insulin-like growth factor binding protein 52011
- Author(s)
  Osaki T, Sasaki K, Minamino N
- Organizer
  第48回ペプチド討論会
- Place of Presentation
  札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-23310155
[Presentation] Secretopeptidome and discovery of new biologically active peptides2011
- Author(s)
  N.Minamino, T.Osaki, K.Sasaki
- Organizer
  9th Australian Peptide Conference
- Place of Presentation
  オーストラリア,Hamilton Island(招待講演)
- Year and Date
  2011-10-17
- Data Source
  KAKENHI-PROJECT-23310155
[Presentation] セクレトペプチドーム解析に基づく新規生理活性ペプチド探索2011
- Author(s)
  佐々木一樹, 高橋憲行, 佐藤光男, 山崎基生, 南野直人
- Organizer
  第84回日本内分泌学会学術総会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-23310155
[Presentation] 質量分析を活用する分泌ペプチドーム解析と生理活性ペプチド探索2010
- Author(s)
  佐々木一樹
- Organizer
  日本内分泌学会内分泌代謝学セミナー
- Place of Presentation
  長崎
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-22591023
[Presentation] 質量分析を活用する分泌ペプチドーム解析と生理活性ペプチド探索2010
- Author(s)
  佐々木一樹
- Organizer
  日本内分泌学会第28回内分泌代謝学サマーセミナー
- Year and Date
  2010-07-09
- Data Source
  KAKENHI-PROJECT-22591023
[Presentation] 新規生理活性ペプチドNERPのラットにおける生体内分布と内在性分子型2008
- Author(s)
  三城恵美, 佐々木一樹, 山口秀樹, 里見佳典, 石津雄大, 熊谷久美子, 高尾敏文, 中里雅光, 南野直人
- Organizer
  第81回日本内分泌学会学術総会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-18310138
[Presentation] ペプチドミクスに基づく生理活性ペプチド探索2008
- Author(s)
  佐々木一樹, 里見佳典, 山口秀樹, 中里雅光, 高尾敏文, 南野直人
- Organizer
  日本プロテオーム機構第6回大会
- Place of Presentation
  大阪、シンポジウム
- Data Source
  KAKENHI-PROJECT-18310138
[Presentation] ペプチドミクスの手法を活用した新規生理活性ペプチドNERPの同定2008
- Author(s)
  佐々木一樹, 里見佳典, 山口秀樹, 高尾敏文, 中里雅光, 南野直人
- Organizer
  第81回日本内分泌学会学術総会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-18310138
[Presentation] Peptidomics-based identification and biological characterization of neuroendocrine regulatory peptide-1 and -22008
- Author(s)
  N. Minamino, K. Sasaki, H. Yamaguchi, et al.
- Organizer
  International Symposium on Biologically Active Peptides : Peptide Diversity
- Place of Presentation
  仙台(東北大学艮陵会館)
- Year and Date
  2008-09-01
- Data Source
  KAKENHI-PROJECT-18310138
[Presentation] 新規生理活性ペプチドNERPのラットにおける生体内分布、内在性分子型と機能2008
- Author(s)
  三城恵美, 佐々木一樹, 山口秀樹, 里見佳典, 石津雄太, 熊谷久美子, 高尾敏文, 中里雅光, 南野直人
- Organizer
  第81回日本生化学会大会・第31日本分子生物学会年会合同大会
- Place of Presentation
  神戸、ポスター
- Data Source
  KAKENHI-PROJECT-18310138
[Presentation] ペプチドーム解析法を用いた新規生理活性ペプチドNERP-1とNERP-2の同定2007
- Author(s)
  南野直人, 佐々木一樹, 里見佳典, 山口秀樹, 高尾敏文, 中里雅光
- Organizer
  第44回ペプチド討論会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-18310138
[Presentation] Peptidomic analysis for identification of endogenous peptides and precursor processing pathway2007
- Author(s)
  N. Minamino, K. Sasaki, T. Osaki, Y. Satomi, T. Takao
- Organizer
  4th International Peptide Symposium, 7th Australian Peptide Conference, and 2nd Asia-Pacific Peptide Symposium
- Place of Presentation
  ケアンズ、オーストラリア
- Data Source
  KAKENHI-PROJECT-18310138
[Presentation] ペプチドーム解析による新規ペプチド探索2007
- Author(s)
  佐々木一樹, 南野直人
- Organizer
  大阪大学蛋白質研究所セミナー「ペプチドの真価 : 検出・探索から診断・創薬へ
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18310138
[Presentation] ペプチドミクスを活用した新規生理活性ペプチドの発見2007
- Author(s)
  佐々木一樹, 山口秀樹, 里見佳典, 高尾敏文, 中里雅光, 南野直人
- Organizer
  第80回日本生化学会大会、第30日本分子生物学会年会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18310138
[Presentation] Peptidomic analysis for identification of endogenous peptides and precursor processing pathway2007
- Author(s)
  N. Minamino, K. Sasaki, T. Osaki
- Organizer
  4th International Peptide Symposium
- Place of Presentation
  オーストラリア、ケアンズ
- Year and Date
  2007-10-25
- Data Source
  KAKENHI-PROJECT-18310138
[Presentation] ペプチドミクスを活用する生理活性ペプチド探索の新しいアプローチ2007
- Author(s)
  佐々木一樹, 南野直人
- Organizer
  第112回日本解剖学会総会・全国学術集会シンポジウム「新規神経ペプチドの生体システム調節
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-18310138
[Presentation] Peptidome database and identification of new biologically active peptides2006
- Author(s)
  N. Minamino, H. Kuwahara, K. Sasaki, T. Osaki, T. Katafuchi, T. Takao, M Isoyama
- Organizer
  9th Chinese International Peptide Symposium 2006
- Place of Presentation
  上海
- Data Source
  KAKENHI-PROJECT-18310138
[Presentation] PEPTIDOME Database and Identification of New Bioactive Peptides2006
- Author(s)
  N. Minamino, H. Kuwahara, K. Sasaki, T. Osaki, T. Kihara, J. Isoyama-Tanaka, T. Katafuchi, T. Takao, M. Isoyama
- Organizer
  International Conference : 43rd Japanese Peptide Symposium/4th Peptide Engineering Meeting
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-18310138
[Presentation] 生理活性ペプチド探索のためのペプチドミクス
- Author(s)
  佐々木一樹
- Organizer
  関東ハートセミナー
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-22591023
[Presentation] Utility of electron transfer dissociation mass spectrometry in global analysis of naturally occurring peptides
- Author(s)
  Sasaki K, Osaki T, Minamino N
- Organizer
  4th Asia-Pacific International Peptide Symposium
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-25461402
[Presentation] Peptidomic survey of peptides found in culture supernatant of cardiac fibroblasts-an expanded application to common cells having the constitutive secretory pathway
- Author(s)
  Tsuchiya T, Sasaki K, Osaki T, Minamino N
- Organizer
  4th Asia-Pacific International Peptide Symposium
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-25461402

1. MINAMINO Naoto (50124839)

# of Collaborated Projects: 2 results

# of Collaborated Products: 46 results
2. OSAKI Tsukasa (60380565)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
3. MOCHIZUKI Akikazu (30589601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. TAKAO Toshifumi (10197048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 田中正光 (20291396)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 栗山正 (30398226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 伊藤剛 (60607563)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 竹本さやか

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 中里雅光

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. 山口秀樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 十枝内厚次

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 土持若葉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 市川美紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 中川原章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 迫田秀之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SASAKI KAZUKI 佐々木 一樹

佐々木 一樹 ササキ カズキ

SASAKI Kazuki 佐々木 一樹

Research Projects

Research Products

Co-Researchers

GMN癌細胞の生存戦略とゲノム変異の多様性に基づく再燃・転移の治療開発

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Research Institution

Peptidomics for studying limited proteolysis in pancreatic cancerPrincipal Investigator

Principal Investigator

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Research Institution

Peptidomics for studying biological functions of VGFPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Development of tissue peptidome analysis technology and its application to discovery of new biologically active peptides

Principal Investigator

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Research Institution

Snapshot peptidomics for bioactive peptide discoveryPrincipal Investigator

Principal Investigator

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Tissue-specific processing pathway of precursor proteins deduced from peptidome analysis

Principal Investigator

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Research Institution

血液からのペプチド性腫瘍マーカー探索法の確立Principal Investigator

Principal Investigator

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Research Institution

[Book] Peptidomics strategy for discovering endogenous peptides. (Kastin A ed. In Handbook of Biologically Active Peptides 2^<nd> ed.)2013

Author(s)

Publisher

Data Source

[Book] Peptidomics strategy for discovering endogenous biologically active peptides2013

Author(s)

Publisher

Data Source

[Book] Handbook of the Biologically Active Peptides, Second Edition2013

Author(s)

Total Pages

Publisher

Data Source

[Book] Handbook of Biologically Active Peptides (Second Edition)2013

Author(s)

Total Pages

Publisher

Data Source

[Book] Mass Spectrometry-based Peptidomics for the Discovery of Antimicrobial Peptides2013

Author(s)

Total Pages

Publisher

Data Source

[Book] ペプチド医薬の最前線2012

Author(s)

Total Pages

Publisher

Data Source

[Book] ペプチドミクを活用する生理活性ペプチドの探索. ファインケミカルシリーズ ペプチド医薬の最前線(木曽良明、向井秀仁編)2012

Author(s)

Publisher

Data Source

SASAKI KAZUKI 佐々木一樹

佐々木一樹ササキカズキ

SASAKI Kazuki 佐々木一樹

[Book] ペプチドミクを活用する生理活性ペプチドの探索. ファインケミカルシリーズペプチド医薬の最前線(木曽良明、向井秀仁編)2012