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OTSUBO Kenji  大坪 健司

ORCIDConnect your ORCID iD *help
Researcher Number 80260701
Other IDs
Affiliation (based on the past Project Information) *help 2005 – 2007: 鳥取大学, 医学部附属病院, 教授
2002 – 2003: 鳥取大学, 医学部附属病院, 教授
2001: 鳥取大学, 医学部・附属病院, 教授
Review Section/Research Field
Except Principal Investigator
応用薬理学・医療系薬学 / Medical pharmacy
Keywords
Except Principal Investigator
CYP3A4 / CYP3A5 / 臨床試験 / BCRP / MDR1 / SNPs / clinical study / itraconazole / midazolam / epigenetics … More / allelic expression imbalance / イトラコノナゾール / ミダゾラム / ヒストンアセチル化 / メチル化 / エピジェネティックス / アレル不均等発現 / Clinical Study / Basic research / P-glycoprotein / ABC transporters / オーダーメイド医療 / ジゴキシン / モルヒネ / 遺伝子多型 / 薬物脳移行 / MRPs遺伝子 / MDR1遺伝子 / 中枢毒性 / 部分肝移植 / タクロリムス / diplotype / hapolotype / 胎盤 / 4MU / 基礎研究 / p-糖タンパク / ABCトランスポーター / インプリント / アレル発現パターン / インプリンティング制御 Less
  • Research Projects

    (3 results)
  • Research Products

    (2 results)
  • Co-Researchers

    (5 People)
  •  The role of allelic expression imbalance (AER) in interindividual differences in CYP3A4 activity and it's clinical implications.

    • Principal Investigator
      IEIRI Ichiro
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      Kyushu University
  •  ゲノムインプリンティング制御によるCYP3A4発現・機能の個人間変動解析

    • Principal Investigator
      IEIRI Ichiro
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Tottori University
  •  In vivo functional characterization of the ABC transporters based on the genetic polymorphisms

    • Principal Investigator
      IEIRI Ichiro
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Tottori University

All 2006

All Journal Article

  • [Journal Article] Pharmacogenetic determenants of variability in liped-lowering response to pravastat in therapy2006

    • Author(s)
      Takane H, Miyata M, Burioka N, Shioemasa C, Shimizu E, Otsubo K, Ieiri I
    • Journal Title

      J Hum Genet 51

      Pages: 822-826

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17390043
  • [Journal Article] Ieiri I : Pharmacogenetic determinants of variability in lipid-lowering response to pravastatin therapy2006

    • Author(s)
      Takane, H., Miyata, M., Burioka, N., Shigemasa, C., Shimizu, E., Otsubo, K
    • Journal Title

      J Hum Genet 51

      Pages: 822-886

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17390043
  • 1.  IEIRI Ichiro (60253473)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 2.  NANBA Eiji (40237631)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  HIGUCHI Shun (40218699)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  BURIOKA Naoto (50252854)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 5.  URAE Akinori
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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