Utoguchi Naoki 宇都口直樹

… Alternative Names

UTOGUCHI Naoki 宇都口直樹

UTOGUCHI NAOKI 宇都口直樹

宇都口直樹ウトグチナオキ

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Researcher Number	80276633
Other IDs
Affiliation (Current)	2025: 昭和薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2022: 昭和薬科大学, 薬学部, 教授 2016 – 2017: 昭和薬科大学, 薬学部, 教授 2015: 帝京大学, 薬学部, 教授 2011 – 2013: 帝京大学, 薬学部, 教授 2007 – 2008: Teikyo University, 薬学部, 准教授 … More 2004 – 2005: 帝京大学, 薬学部, 助教授 2002: Teikyo University, School of Pharmaceutical Sciences, Associate Professor, 薬学部, 助教授 2001: 昭和薬科大学, 薬学部, 講師 1999: Showa Pharmaceutical University, Faculty of Pharmaceutical Sciences, Assistant Professor, 薬学部, 講師 1996 – 1998: 昭和薬科大学, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator Medical pharmacy / 医薬分子機能学 / Basic Section 47060:Clinical pharmacy-related / Tumor therapeutics / Tumor immunology Except Principal Investigator Environmental pharmacy / 医薬分子機能学 / Medical pharmacy
Keywords	Principal Investigator 血管新生 / 血管内皮細胞 / がん免疫 / 腫瘍擬似血管 / 擬似血管 / 免疫療法 / 樹状細胞 / ターゲティング / 腫瘍疑似血管 / 免疫 … More / がん血管 / がんターゲティング / 腫瘍微小環境 / 腫瘍血管 / ワクチン療法 / がん免疫療法 / 癌免疫 / ワクチン / モノカルボン酸 / トランスポーター / 吸収 / 口腔粘膜 / 特殊輸送系 / 転移 / 白血球 / 細胞間接着 … More Except Principal Investigator 胎盤 / human chorionic gonadotropin / endocrine disruptor / triphenyltin / tributyltin / aromatase / organotin compound / placenta / ヒト絨毛性ゴナトトロピン / ヒト絨毛性ゴナドトロピン / 内分泌撹乱物質 / トリフェニルスズ / トリブチルスズ / アロマターゼ / 有機スズ化合物 / Protein drug / Transmuscosal drug absorption / Absorption-enhancing effect / Nitric oxide donor / Physiological action of nitric oxide / 経粘膜吸収 / 一酸化窒素生理作用 / 蛋白質医薬品 / 経粘膜薬物吸収 / 吸収促進作用 / 一酸化窒素供与剤 / 酸化窒素生理作用 / 透過モデル / 物質透過モデル / 胎盤透過 / 胎盤関門 / 妊娠時薬物療法 / JEG-3 / DJEG / BCRP / トロホブラスト / 物質透過 / モデル Less

Development of novel immunotherapy for malignant brain tumors targeting tumor vascular mimicryPrincipal Investigator
- Principal Investigator
  
  UTOGUCHI Naoki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Showa Pharmaceutical University
Development of novel malignant brain tumor therapy against tumor vascular mimicry derived from tumor cellsPrincipal Investigator
- Principal Investigator
  
  UTOGUCHI Naoki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Showa Pharmaceutical University
  Teikyo University
Development of novel cancer immunotherapy targeting tumo vascular mimicryPrincipal Investigator
- Principal Investigator
  
  UTOGUCHI NAOKI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor immunology
- Research Institution
  Teikyo University
In vitro approaches to evaluate placental drug transport by using differentiating JEG-3 human choriocarcinoma cells
- Principal Investigator
  
  IKEDA Kenji
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Osaka Ohtani University
Development of novel brain tumor immunotherapy against brain tumor vesselPrincipal Investigator
- Principal Investigator
  
  UTOGUCHI Naoki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Teikyo University
腫瘍組織血管内皮細胞をパルスした樹状細胞による新規癌免疫法の開発Principal Investigator
- Principal Investigator
  
  宇都口直樹
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Teikyo University
Effects of organotin compounds on the endocrine functions of placenta.
- Principal Investigator
  
  TANAKA Keiichi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Osaka University
Studies on the development of new drug adsorption-enhancing systems based on physiological action of nitric oxide (NO)
- Principal Investigator
  
  WATANABE Yoshiteru
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  医薬分子機能学
- Research Institution
  Showa Pharmaceutical University
粘膜における薬物特殊輸送系を利用した新規薬物送達法の開発Principal Investigator
- Principal Investigator
  
  宇都口直樹
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  医薬分子機能学
- Research Institution
  Showa Pharmaceutical University
癌細胞-血管内皮細胞間接着阻害を作用機序とした新規癌転移抑制剤の開発Principal Investigator
- Principal Investigator
  
  宇都口直樹
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  医薬分子機能学
- Research Institution
  Showa Pharmaceutical University

All 2023 2022 2021 2020 2018 2017 2016 2015 2012 2011 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Cancer vaccine therapy using tumor endothelial cells as antigens suppresses solid tumor growth and metastasis2017
- Author(s)
  Nomura T, Hirata K, Shimaoka T, Yamakawa M, Koizumi N, Suzuki R, Maruyama K, Utoguchi N
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 40 Pages: 1661-1668
- NAID
  130006110548
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06881
[Journal Article] Efflux transporter mRNA expression profiles in differentiating JEG-3 human choriocarcinoma cells as a placental transport model2012
- Author(s)
  池田賢二、山﨑恭平、保米本愛美、山上聡子、小川雅史、中尾絵莉奈、福永悠海、中西剛、宇都口直樹、名德倫明、廣谷芳彦
- Journal Title
  
  Pharmazie
  
  Volume: 67巻 Pages: 88-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590207
[Journal Article] In Vitro Approaches to Evaluate Placental Drug Transport by Using Differentiating JEG-3 Human Choriocarcinoma Cells2011
- Author(s)
  池田賢二、宇都口直樹、筒居秀伸、山上聡子、保米本愛美、中尾絵莉奈、福永悠海、山﨑恭平、名德倫明、廣谷芳彦
- Journal Title
  
  Basic Clin. Pharmacol. Toxicol
  
  Volume: 108巻 Pages: 138-145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590207
[Presentation] In vitro 再構築モデルを用いたがん擬似血管構成細胞の特性解析2023
- Author(s)
  野村鉄也, 小倉一桜, 仁井田怜子, 萩原芙美子, 小泉直也, 宇都口直樹
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K07187
[Presentation] Development of Dendritic cell-based immunotherapy targeting tumor blood vessels in a mouse model of lung metastasis2022
- Author(s)
  Tetsuya Nomura, Naoki Utoguchi
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07187
[Presentation] 腫瘍血管を標的とした治療法開発を目指したin vitro腫瘍血管内皮細胞モデルの特性解析2022
- Author(s)
  野村鉄也, 山下千紗都, 小泉直也, 宇都口直樹
- Organizer
  日本薬剤学会第37年会
- Data Source
  KAKENHI-PROJECT-20K07187
[Presentation] Characteristic analysis of novel tumor derived endothelial cells-specific antibody2022
- Author(s)
  Tetsuya Nomura, Mai Furukawa, Yuuka Kawashima, Naoki Utoguchi
- Organizer
  第16回次世代を担う若手のための医療薬科学シンポジウム
- Data Source
  KAKENHI-PROJECT-20K07187
[Presentation] メラノーマによるがん擬似血管構造を再現しうるin vitro再構築モデルの開発と特性解析2022
- Author(s)
  野村鉄也, 平田圭一, 小泉直也, 宇都口直樹
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20K07187
[Presentation] がん擬似血管を抗原として利用した樹状細胞免疫療法の開発に向けた基礎的検討2021
- Author(s)
  高野涼、國友瑞穂、野村鉄也、小泉直也、宇都口直樹
- Organizer
  第36回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07187
[Presentation] がん擬似血管再構築モデルの開発と管腔形成メカニズムの解明に関する基礎的検討2020
- Author(s)
  野村　鉄也, 宮崎賢太郎, 酒井慶伍, 仁井田怜子, 國友瑞穂, 小泉直也, 宇都口直樹
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20K07187
[Presentation] がん微小環境における免疫抑制機構の制御を可能にする受容体指向性サイトカインアンタゴニストの創製2020
- Author(s)
  野村鉄也, 井上隼輔, 多田遥子, 井上雅己, 鎌田春彦, 角田慎一, 宇都口直樹
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-20K07187
[Presentation] In vitroがん血管モデルを用いた免疫療法の新生血管に対する影響の評価2018
- Author(s)
  野村鉄也, 山川真希枝, 平井孝昌, 小泉直也, 宇都口直樹
- Organizer
  日本薬学会 138年会
- Data Source
  KAKENHI-PROJECT-15K06881
[Presentation] 腫瘍血管内皮細胞を標的とした樹状細胞ワクチン療法による抗腫瘍効果と抗原特異的免疫誘導能の解析2018
- Author(s)
  山川真希枝, 野村鉄也, 平井孝昌, 小泉直也, 宇都口直樹
- Organizer
  日本薬学会 138年会
- Data Source
  KAKENHI-PROJECT-15K06881
[Presentation] がん血管を標的とした樹状細胞免疫療法の開発2017
- Author(s)
  野村鉄也, 山川真希枝, 小泉直也, 宇都口　直樹
- Organizer
  第33回日本DDS学会
- Data Source
  KAKENHI-PROJECT-15K06881
[Presentation] 腫瘍血管内皮細胞をワクチン抗原として利用したがん免疫療法の有効性評価2017
- Author(s)
  山川真希枝, 野村鉄也, 小泉直也, 宇都口直樹
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県　仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K06881
[Presentation] がん血管を抗原として利用したがん免疫療法はがん増殖や転移を効果的に抑制する2017
- Author(s)
  野村鉄也, 宇都口直樹
- Organizer
  第11回医療薬科学若手シンポジウム
- Data Source
  KAKENHI-PROJECT-15K06881
[Presentation] 難治性乳がんにおける擬似血管構造を標的とした新規抗体の創製2016
- Author(s)
  岡部理恵子, 野村鉄也, 山﨑麗, 平田圭一, 宇都口　直樹
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15K06881
[Presentation] 腫瘍血管内皮細胞に対する特異抗体の創出と特性評価2015
- Author(s)
  宮口聖総, 野村鉄也,　野村香織, 平田圭一,　宇都口直樹
- Organizer
  第59回日本薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-15K06881
[Presentation] がん組織における擬似血管構造を標的とした新規抗体の創製2015
- Author(s)
  野村鉄也, 阿部正人, 平田圭一, 長野一也, 堤康央, 角田慎一, 宇都口直樹
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K06881
[Presentation] 腫瘍組織より分離した血管内皮細胞を抗原とした樹状細胞によるがん免疫療法2009
- Author(s)
  嶋岡卓人、宇都口直樹、鈴木亮、丸山一雄
- Organizer
  日本薬学会第129 年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590160
[Presentation] 腫瘍組織より分離した血管内皮細胞を抗原としたがん免疫療法2008
- Author(s)
  嶋岡卓人、宇都口直樹、鈴木亮、丸山一雄
- Organizer
  日本薬剤学会第23年会
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-19590160
[Presentation] 腫瘍組織血管内皮細胞を抗原としたがん免疫療法の開発2008
- Author(s)
  嶋岡卓人、宇都口直樹、鈴木亮、丸山一雄
- Organizer
  ファーマ・バイオフォーラム2008
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590160
[Presentation] 腫瘍組織より単離した血管内皮細胞を標的としたがん免疫療法の開発2008
- Author(s)
  宇都口直樹、鈴木亮、丸山一雄
- Organizer
  第67 回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19590160
[Presentation] 腫瘍組織より単離した血管内皮細胞を標的としたがん免疫療法の開発2008
- Author(s)
  宇都口直樹
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-19590160
[Presentation] 腫瘍組織血管内皮細胞を抗原としてパルスした樹状細胞による癌免疫療法2007
- Author(s)
  宇都口直樹
- Organizer
  第16回日本がん転移学会
- Place of Presentation
  富山国際会議場
- Year and Date
  2007-07-10
- Data Source
  KAKENHI-PROJECT-19590160
[Presentation] がん組織における擬似血管新生を標的とした免疫療法の開発
- Author(s)
  野村鉄也、宇都口直樹
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学黒髪キャンパス
- Data Source
  KAKENHI-PROJECT-23501288

1. IKEDA Kenji (10434812)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. HIROTANI Yoshihiko (00351487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. MYOTOKU Michiaki (30469233)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. WATANABE Yoshiteru (70175131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MATSUMOTO Mitsuo (10077513)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. FUJII Makiko (50199296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ENDO Kazutoyo (50106598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TANAKA Keiichi (90068247)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. ITOH Norio (60176352)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NAKANISHI Tsuyoshi (50303988)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Utoguchi Naoki 宇都口 直樹

UTOGUCHI Naoki 宇都口 直樹

UTOGUCHI NAOKI 宇都口 直樹

宇都口 直樹 ウトグチ ナオキ

Research Projects

Research Products

Co-Researchers

Development of novel immunotherapy for malignant brain tumors targeting tumor vascular mimicryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel malignant brain tumor therapy against tumor vascular mimicry derived from tumor cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel cancer immunotherapy targeting tumo vascular mimicryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

In vitro approaches to evaluate placental drug transport by using differentiating JEG-3 human choriocarcinoma cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel brain tumor immunotherapy against brain tumor vesselPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

腫瘍組織血管内皮細胞をパルスした樹状細胞による新規癌免疫法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of organotin compounds on the endocrine functions of placenta.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the development of new drug adsorption-enhancing systems based on physiological action of nitric oxide (NO)

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

粘膜における薬物特殊輸送系を利用した新規薬物送達法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

癌細胞-血管内皮細胞間接着阻害を作用機序とした新規癌転移抑制剤の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cancer vaccine therapy using tumor endothelial cells as antigens suppresses solid tumor growth and metastasis2017

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Efflux transporter mRNA expression profiles in differentiating JEG-3 human choriocarcinoma cells as a placental transport model2012

Author(s)

Journal Title

Data Source

[Journal Article] In Vitro Approaches to Evaluate Placental Drug Transport by Using Differentiating JEG-3 Human Choriocarcinoma Cells2011

Author(s)

Journal Title

Data Source

Utoguchi Naoki 宇都口直樹

UTOGUCHI Naoki 宇都口直樹

UTOGUCHI NAOKI 宇都口直樹

宇都口直樹ウトグチナオキ