KOTOH Kazuhiro 古藤和浩

Researcher Number	80289579
Affiliation (based on the past Project Information) *help	2013 – 2015: 九州大学, 大学病院, 講師 2013: 九州大 2011: 九州大学, 大学病院, 講師 2009 – 2011: 九州大学, 大学病院, 助教 2005 – 2006: 九州大学, 大学病院, 助手 2002: Kyushu University Hospital Assistant Professor, 医学部附属病院, 助手 2001: 九州大学, 医学部・附属病院, 助手
Review Section/Research Field	Principal Investigator Gastroenterology Except Principal Investigator Gastroenterology / Science and Engineering
Keywords	Principal Investigator hepatic stellate cells / animal model / oleic acid / linoreic acid / fatty acids / glucose / NASH / fatty liver / 過酸化脂質 / 脂肪酸 … More / ADRP / 遺伝子治療 / インスリン / リノール酸 / オレイン酸 / 肝障害 / 脂肪酸代謝 / 糖代謝 / 脂肪肝 … More Except Principal Investigator NASH / ROS / AMPK / NAFLD / 脂肪肝 / Insulin / Oxidation / Fatty acid metabolism / Fatty liver / SREBP1 / 脂肪酸酸化 / 脂肪酸合成 / インスリン / 活性酸素 / 酸化 / 脂肪酸代謝 / 定量的PCR / 類洞血流 / 肝硬変 / 慢性肝炎 / VEGFR2 / VEGFA / HO-1 / hedgehog / p21 / adrenomedullin / indian hedgehog / 末梢血単核球 / 肝星細胞 / 肝発癌 / 肝線維化 / 低酸素 / HepG2細胞 / HOMA-IR / RT-PCR / GIP / DPP-4 / インスリン抵抗性 / インクレチン / 糖尿病 / GLP-1 / 脂肪性肝炎 / Open MRI / ナビゲーション / トレーニング / デジタルサージャン / 治療シミュレーション / 低侵襲治療 / 画像誘導治療 / 計算解剖モデル / 計測工学 / 電気電子工学 / 内視鏡外科 / 手術ロボット / 臨床応用 / 手術ナビゲーション / 手術シミュレーション / 計算解剖学 Less

Analyses of the effects of hypoxia on the progression of liver disease and hepatic carcinogenesis.
- Principal Investigator
  
  Kato Masaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyushu University
Clinical Application of Navigation Surgery Assisted by the Computational Anatomy
- Principal Investigator
  
  HASHIZUME Makoto
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyushu University
Analysis of therapeutic effects of GLP-1, novel anti妖iabetic medication, on non-allcoholic fatty liver disease and steatohepatitis.
- Principal Investigator
  
  KATO Masaki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyushu University
Evaluation of fatty acid metabolism-related gene expression in non-alcoholic fatty liver disease
- Principal Investigator
  
  NAKAMUTA Makoto
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyushu Medical Center, National Hospital Organization
  Kyushu University
Nobel Strategy of Treatment for Non-alcoholic SteatohepatitsPrincipal Investigator
- Principal Investigator
  
  KOTOH Kazuhiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyushu University

All 2016 2014 2012 2011 2010 2005 Other

All Journal Article Presentation

[Journal Article] Intrahepatic microcirculatory disorder, parenchymal hypoxia and NOX4 upregulation result in zonal differences in hepatocyte apoptosis following lipopolysaccharide- and D-galactosamine-induced acute liver failure in rats.2014
- Author(s)
  Tanaka M, Tanaka K, Masaki Y, Miyazaki M, Kato M, Kotoh K, Enjoji M, Nakamuta M, Takayanagi R.
- Journal Title
  
  Int J Mol Med.
  
  Volume: 33 Issue: 2 Pages: 254-62
- DOI
  10.3892/ijmm.2013.1573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461000
[Journal Article] Increased hepatic expression of dipeptidyl peptidase-4 in nonalcoholic fatty liver disease and its association with insulin resistance and glucose metabolism2012
- Author(s)
  Miyazaki M, Kato M, Tanaka M, Kohjima M, Nakamura K, Enjoji M, Nakamuta M, Kotoh K, Takayanagi R.
- Journal Title
  
  Mol Med Report
  
  Volume: 5 Pages: 729-733
- DOI
  10.3892/mmr.2011.707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590850
[Journal Article] Effects of insulin resistance and hepatic lipid accumulation on hepatic mRNA expression levels of apoB, MTP, and L-FABP in nonalcoholic fatty liver disease2011
- Author(s)
  Higuchi N, Kato M, Tanaka M, Miyazaki M, Takao S, Kohjima M, Kotoh K, Enjoji M, Nakamuta M, Takayanagi R.
- Journal Title
  
  Experimental and Therapeutic Medicine
  
  Volume: 2 Issue: 6 Pages: 1077-81
- DOI
  10.3892/etm.2011.328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590850
[Journal Article] Evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease.2005
- Author(s)
  Nakamuta M, Kohjima M, Morizono S, Kotoh K, Yoshimoto T, Miyagi I, Enjoji M.
- Journal Title
  
  Int J Mol Med. 16(4)
  
  Pages: 631-5
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590658
[Presentation] 末梢血単核球を用いた慢性疾患患者における低酸素ストレスと炎症マーカー、血管新生関連因子の評価2016
- Author(s)
  桑野哲史、田中紘介、山崎晃裕、大橋朋子、加藤正樹、古藤和浩
- Organizer
  第52回日本肝臓学会
- Place of Presentation
  千葉
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-25461000
[Presentation] NAFLD症例におけるDPP-4発現の評価2010
- Author(s)
  宮崎将之、樋口野日斗、加藤正樹、古藤和浩、高柳涼一
- Organizer
  第38回日本肝臓学会東部会
- Place of Presentation
  東京
- Year and Date
  2010-12-02
- Data Source
  KAKENHI-PROJECT-21590850
[Presentation] 末梢血単核球を用いた、慢性肝疾患症例の低酸素ストレスレベルの評価の可能性
- Author(s)
  田中紘介, 田中正剛, 真崎由子, 山崎晃裕, 原田林, 梅野成大, 加藤正樹, 遠城寺宗近, 中牟田誠, 古藤和浩, 髙栁涼一
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-25461000
[Presentation] チオアセトアミド投与ラット肝硬変モデルにおける肝星細胞活性化とヘッジホッグシグナルの関連性についての組織学的検討
- Author(s)
  田中正剛、加藤正樹、田中紘介、宮崎将之、古藤和浩
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  東京
- Year and Date
  2014-05-29 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-25461000

1. INOGUCHI Toyoshi (00294926)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. NAKAMUTA Makaoto (00294918)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. KATO Masaki (60444808)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. ENJOJI Munechika (20253411)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. HASHIZUME Makoto (90198664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SUZUKI Naoki (40147327)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SUGIMOTO Maki (70398733)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KIGUCHI Kazuo (90269548)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HONG Jaesung (70404043)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TOMIKAWA Morimasa (60325454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. IEIRI Satoshi (00363359)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. OHUCHIDA Kenoki (20452708)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KONISHI Kozo (90380641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TANOUE Kazuo (40294920)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KOTOH Kazuhiro 古藤 和浩

Research Projects

Research Products

Co-Researchers

Analyses of the effects of hypoxia on the progression of liver disease and hepatic carcinogenesis.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clinical Application of Navigation Surgery Assisted by the Computational Anatomy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of therapeutic effects of GLP-1, novel anti妖iabetic medication, on non-allcoholic fatty liver disease and steatohepatitis.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of fatty acid metabolism-related gene expression in non-alcoholic fatty liver disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Nobel Strategy of Treatment for Non-alcoholic SteatohepatitsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Intrahepatic microcirculatory disorder, parenchymal hypoxia and NOX4 upregulation result in zonal differences in hepatocyte apoptosis following lipopolysaccharide- and D-galactosamine-induced acute liver failure in rats.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increased hepatic expression of dipeptidyl peptidase-4 in nonalcoholic fatty liver disease and its association with insulin resistance and glucose metabolism2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of insulin resistance and hepatic lipid accumulation on hepatic mRNA expression levels of apoB, MTP, and L-FABP in nonalcoholic fatty liver disease2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of fatty acid metabolism-related gene expression in nonalcoholic fatty liver disease.2005

Author(s)

Journal Title

Description

Data Source

[Presentation] 末梢血単核球を用いた慢性疾患患者における低酸素ストレスと炎症マーカー、血管新生関連因子の評価2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] NAFLD症例におけるDPP-4発現の評価2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 末梢血単核球を用いた、慢性肝疾患症例の低酸素ストレスレベルの評価の可能性

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] チオアセトアミド投与ラット肝硬変モデルにおける肝星細胞活性化とヘッジホッグシグナルの関連性についての組織学的検討

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

KOTOH Kazuhiro 古藤和浩