YOSHIKAWA Yuko 吉川祐子

Researcher Number	80291871
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2017: 同志社大学, 生命医科学部, 嘱託講師 2017: 立命館大学, 生命科学部, 教授 2012 – 2015: 立命館大学, 総合科学技術研究機構, 教授 2009 – 2011: Ritsumeikan University, 総合理工学研究機構, 教授 2007 – 2009: International Pacific University, 次世代教育学部, 教授 … More 2004 – 2006: Nagoya Bunri College, Department of Food and Nutrition, Professor, 食物栄養学科, 教授 2003: 名古屋文理短期大学, 食物栄養学科, 教授 1999 – 2002: 名古屋文理短期大学, 食物栄養学科, 助教授 Less
Review Section/Research Field	Principal Investigator Nanomaterials/Nanobioscience / ポストゲノムのナノサイエンス / Nanobioscience / Science and Engineering Except Principal Investigator Drug development chemistry / Physical pharmacy / Science and Engineering
Keywords	Principal Investigator 長鎖DNA / DNA損傷 / 蛍光顕微鏡 / DNAの高次構造 / 単一分子観察 / fluorescence microscopy / higher order structure / long duplex DNA / 折り畳み構造 / 高次構造 … More / 環境応答 / 原子間力顕微鏡 / ビタミンC / 二本鎖切断 / 再構成クロマチン / 抗酸化物質 / 単分子観察 / ナノバイオ / daunomycin / ascorbic acid / reconstituted chromatin / double-strand break / single-molecule observation / リポソーム / 蛍光顕微鏡観察 / DNAの折りたたみ構造 / パーリング構造 / 自己組織化ナノ構造 / アスコルビン酸 / 抗酸化作用 / ダウノマイシン / 単一分子観察法 / laser manipulation / histone H1 / ヒストンH1 / レーザー / ヒルトンH1 / ポリアミン / １分子イメージング / 構造機能相関 / 長鎖DNAの高次構造 / 一分子イメージング / 二重鎖切断 / 抗がん剤 / 1分子計測 / DNA高次構造 / 放射線損傷 / 遺伝子機能 / 活性酸素 / DNA二本鎖切断 … More Except Principal Investigator ペプチド / 固相合成 / ポリアミン / 薬物耐性 / 細胞内取込 / 核酸 / 金属錯体 / 白金制がん剤 / 細胞内蓄積 / 抗腫瘍効果 / 大腸がん / オキサリプラチン / 白金製剤 / 難治性がん / 創薬 / DDS / 制がん剤 / 白金錯体 / 人工細胞 / 膜タンパク / 人工モデル細胞 / 膜タンパク質 / 無細胞翻訳系 / 転写系 / リボソーム / in vitro翻訳 / in vitro転写 / ゲノム / 再構成系 / in vitro翻訳系 / in vitro転写系 / 超好熱菌 Less

Drug discovery research based on dinuclear platinum complexes with markedly high antitumor activity
- Principal Investigator
  
  Komeda Seiji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Suzuka University of Medical Science
Conformationally restricted polyamines: Solid-phase synthesis and biological evaluation
- Principal Investigator
  
  Umezawa Naoki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Nagoya City University
Controlling the higher-order structure of genomic DNA in relation to its genetic activityPrincipal Investigator
- Principal Investigator
  
  YOSHIKAWA Yuko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nanobioscience
- Research Institution
  Ritsumeikan University
Controlling the higher order structure of single DNA molecule with attention to environmental stressPrincipal Investigator
- Principal Investigator
  
  YOSHIKAWA Yuko
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  Ritsumeikan University
DNAの高次構造変化と環境応答:その場操作の活用Principal Investigator
- Principal Investigator
  
  吉川祐子
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Ritsumeikan University
  International Pacific University
Development of a genome-scale in vitro transcription and translation-coupled system
- Principal Investigator
  
  IMANAKA Tadayuki
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Ritsumeikan University
  Kyoto University
pplication of Single-Molecule Observation for Kinetic Analysis of Genomic DNA Double-Strand Breaks in Relation to Genetic ActivityPrincipal Investigator
- Principal Investigator
  
  YOSHIKAWA Yuko
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  International Pacific University
  College of Nagoya Bunri University
Dynamical Structural Change of Reconstituted Chromatin and Its Genetic ActivityPrincipal Investigator
- Principal Investigator
  
  YOSHIKAWA Yuko
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  ポストゲノムのナノサイエンス
- Research Institution
  College of Nagoya Bunri University
Morphological Variation of Higher Order Structure of Long Duplex DNA and its genetic activityPrincipal Investigator
- Principal Investigator
  
  YOSHIKAWA Yuko
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Institution
  College of Nagoya Bunri University

[Book] 『栄養・食糧学用語辞典』日本栄養・食糧学会編(項目分担 : 総著者数283名)2007
- Author(s)
  吉川祐子
- Total Pages
  808
- Publisher
  建帛社
- Data Source
  KAKENHI-PROJECT-17510102
[Book] "Physical Chemistry of DNA-Carrier Complex" in Non-viral Gene Therapy : Gene Design and Delivery(Eds. K. Taira, K. Kataoka, T. Niidome)2005
- Author(s)
  K. Yoshikawa, Y. Yoshikawa
- Publisher
  Springer-Verlag, Tokyo
- Data Source
  KAKENHI-PROJECT-17510102
[Book] Non-viral Gene Therapy : Gene Design and Delivery2005
- Author(s)
  Kenichi Yoshikawa
- Publisher
  Springer-Verlag Tokyo, Inc.(印刷中)
- Data Source
  KAKENHI-PROJECT-14598005
[Journal Article] Specific Conformational Change in Giant DNA Caused by Anticancer2017
- Author(s)
  S. Komeda, H. Yoneyama, M. Uemura, A. Muramatsu, N. Okamoto,
- Journal Title
  
  Inorg. Chem.
  
  Volume: 56 Issue: 2 Pages: 802-811
- DOI
  10.1021/acs.inorgchem.6b02239
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460160, KAKENHI-PROJECT-15K07905, KAKENHI-PLANNED-25103012
[Journal Article] Conformational transition of DNA by dinuclear Pt(II) complexes causes cooperative inhibition of gene expression2017
- Author(s)
  Shimizu, Y.; Yoshikawa, Y.; Kenmotsu, T.; Komeda, S.; Yoshikawa, K.
- Journal Title
  
  Chemical Physics Letters
  
  Volume: 678 Pages: 123-129
- DOI
  10.1016/j.cplett.2017.04.039
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07905, KAKENHI-PROJECT-15H02121
[Journal Article] Naturally occurring branched-chain polyamines induce a crosslinked meshwork structure in a giant DNA.2016
- Author(s)
  Muramatsu,A., Shimizu,Y., Yoshikawa, Y., Fukuda,W., Umezawa,N., Horai,Y., Higuchi,T., Fujiwara,S., Imanaka,T.,Yoshikawa,K.
- Journal Title
  
  J.Chem. Phys. J. Chem. Phys.
  
  Volume: 145 Issue: 23 Pages: 235103-235103
- DOI
  10.1063/1.4972066
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26292045, KAKENHI-PROJECT-15K08027, KAKENHI-PLANNED-25103012, KAKENHI-PROJECT-15H02121
[Journal Article] Chromatin folding and DNA replication inhibition mediated by a highly antitumor-active tetrazolato-bridged dinuclear platinum(II) complex.2016
- Author(s)
  Imai R, Komeda S, Shimura M, Tamura S, Matsuyama S, Nishimura K, Rogge R, Matsunaga A, Hiratani I, Takata H, Uemura M, Iida Y, Yoshikawa Y, Hansen JC, Yamauchi K, Kanemaki MT, Maeshima K.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 24712-24725
- DOI
  10.1038/srep24712
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07905, KAKENHI-PROJECT-16K15095, KAKENHI-PROJECT-16H04746
[Journal Article] Highly Concentrated Ethanol Solutions: Good Solvents for DNA as Revealed by Single-Molecule Observation2016
- Author(s)
  Oda Y., Sadakane K., Yoshikawa Y., Imanaka T., Takiguchi K., Hayashi M., Kenmotsu T. and Yoshikawa K.
- Journal Title
  
  ChemPhysChem
  
  Volume: 17 Issue: 4 Pages: 471-473
- DOI
  10.1002/cphc.201500988
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24104004, KAKENHI-PROJECT-25390038, KAKENHI-PLANNED-25103012, KAKENHI-PROJECT-15H02121
[Journal Article] Protective Effect of Ascorbic Acid against Double-strand Breaks in Giant DNA: Marked Differences among the Damage Induced by Photo-irradiation, Gamma-rays and Ultrasound2015
- Author(s)
  Yue Ma, Naoki Ogawa, Yuko Yoshikawa, Toshiaki Mori, Tadayuki Imanaka, Yoshiaki Watanabe and Kenichi Yoshikawa
- Journal Title
  
  Chemical Physics Letters
  
  Volume: 638 Pages: 205-209
- DOI
  10.1016/j.cplett.2015.08.054
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02121, KAKENHI-PROJECT-25390038, KAKENHI-PLANNED-25103012
[Journal Article] Structurally Diverse Polyamines: Solid-Phase Synthesis and Interaction with DNA2015
- Author(s)
  Naoki Umezawa1, Yuhei Horai,. Yuki Imamura, Makoto Kawakubo, Mariko Nakahira, Nobuki Kato, Akira Muramatsu, Yuko Yoshikawa, Kenichi Yoshikawa, Tsunehiko Higuchi
- Journal Title
  
  ChemBioChem
  
  Volume: 16 Issue: 12 Pages: 1811-1819
- DOI
  10.1002/cbic.201500121
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08027, KAKENHI-PROJECT-25390038, KAKENHI-PROJECT-25460019
[Journal Article] Identification of a novel aminopropyltransferase involved in the synthesis of branched-chain polyamines in hyperthermophiles.2014
- Author(s)
  Okada K, Hidese R, Fukuda W, Niitsu M, Takao K, Horai Y, Umezawa N, Higuchi T, Oshima T, Yoshikawa Y, Imanaka T, Fujiwara S
- Journal Title
  
  J.Bacteriol.
  
  Volume: 196 Issue: 10 Pages: 1866-1876
- DOI
  10.1128/jb.01515-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580121, KAKENHI-PROJECT-24310015, KAKENHI-PROJECT-24590142, KAKENHI-PROJECT-25390038
[Journal Article] Effect of low-frequency ultrasound on double-strand breaks in giant DNA molecules2013
- Author(s)
  Kenji Yoshida, Naoki Ogawa, Kagawa Yukihiro, Hiraku Tabata, Yoshiaki Watanabe, Takahiro Kenmotsu, Yuko Yoshikawa and Kenichi Yoshikawa
- Journal Title
  
  Applied Physics Letters
  
  Volume: 103 Issue: 6 Pages: 63705-63705
- DOI
  10.1063/1.4818125
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240044, KAKENHI-PROJECT-25390038
[Journal Article] Effective Chiral Discrimination of Tetravalent Polyamines on Single-DNA Compaction2013
- Author(s)
  Yuko Yoshikawa, Naoki Umezawa, Yuki Imamura, Toshio Kanbe, Nobuki Kato, Kenichi Yoshikawa, Tadayuki Imanaka, Tsunehiko Higuchi
- Journal Title
  
  Angew. Chem. Int. Ed.
  
  Volume: 52 Issue: 13 Pages: 3712-3716
- DOI
  10.1002/anie.201209144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J10645, KAKENHI-PROJECT-22510123, KAKENHI-PROJECT-23659058, KAKENHI-PROJECT-24590142, KAKENHI-PROJECT-25460019
[Journal Article] Second-and higher-order structural changes of DNA induced by antitumor-active tetrazolato-bridged dinuclear Platinum(II)complexes with different types of 5-substituent2013
- Author(s)
  M.Uemura, Y.Yoshikawa, T.Sato,Y.Mino, K.Yoshikawa,M.Chikuma,S.Komeda
- Journal Title
  
  J.Inorg. Biochem.
  
  Volume: 127 Pages: 169-174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510123
[Journal Article] Chromatin compaction protects genomic DNA from radiation damage.2013
- Author(s)
  Takata, H., Hanafusa, T., Mori, T., Shimura, M., Iida,Y., Ishikawa, K., Yoshikawa, K., Yoshikawa, Y., Maeshima, K.
- Journal Title
  
  PLOS ONE
  
  Volume: 8 Issue: 10 Pages: e75622-e75622
- DOI
  10.1371/journal.pone.0075622
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23115005, KAKENHI-PROJECT-23370078, KAKENHI-PROJECT-25390038, KAKENHI-PROJECT-25840073
[Journal Article] Structural change of DNA induced by nucleoid proteins: Growth phase-specific Fis and stationary phase-specific Dps2013
- Author(s)
  Yuko T. Sato, Shun N. Watanabe, Takahiro Kenmotsu, Masatoshi Ichikawa, Yuko Yoshikawa, Jun Teramoto, Tadayuki Imanaka, Akira Ishihama and Kenichi Yoshikawa
- Journal Title
  
  Biophysical Journal
  
  Volume: 105 Issue: 4 Pages: 1037-1044
- DOI
  10.1016/j.bpj.2013.07.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240044, KAKENHI-PROJECT-25390038, KAKENHI-PROJECT-25430173
[Journal Article] Highly efficient DNA compaction mediated by an in vivo antitumor-active tetrazolato-bridged dinuclear platinum(II) complex2011
- Author(s)
  Yuko Yoshikawa
- Journal Title
  
  Inorg.Chem.
  
  Volume: Vol.50 Issue: 22 Pages: 11729-11735
- DOI
  10.1021/ic2017165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510123, KAKENHI-PROJECT-23240044
[Journal Article] Critical behavior of megabase-size DNA toward the transition into a compact state2011
- Author(s)
  Yuko Yoshikawa, Yuki Suzuki, Kozo Yamada, Wakao Fukuda, Kenichi Yoshikawa, Kunio Takeyasu, Tadayuki Imanaka
- Journal Title
  
  Journal of Chemical Physics
  
  Volume: 135 Issue: 22 Pages: 225101-225107
- DOI
  10.1063/1.3666845
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J05533, KAKENHI-PROJECT-18GS0421, KAKENHI-PROJECT-22510123, KAKENHI-PROJECT-23240044, KAKENHI-PROJECT-23657068
[Journal Article] Comparative study of kinetics on DNA double-strand break induced byphoto-andgamma-Irradiation:Protective effect of water-soluble flavonoids2010
- Author(s)
  Y.Yoshikawa, T.Mori,M.Suzuki, T.Imanaka, K.Yoshikawa
- Journal Title
  
  Chem.Phys.Lett.
  
  Volume: 501 Pages: 146-151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510123
[Journal Article] Comparative study of kinetics on DNA double-strand break induced by photo-and gamma-Irradiation : Protective effect of water-soluble flavonoids2010
- Author(s)
  Yuko Yoshikawa
- Journal Title
  
  Chem.Phys.Lett.
  
  Volume: 501 Pages: 146-151
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510123
[Journal Article] Controlling the Higher Order Strucutre of DNA-Protamine Complex2009
- Author(s)
  Yuko Yoshikawa
- Journal Title
  
  Proc.of 2009 Int.Symp.on Micro-Nanomechatronics and Human Science
  
  Pages: 305-309
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20034056
[Journal Article] Protein synthesis in giant liposomes using the in vitro translation system of Thermococcus kodakaraensis2009
- Author(s)
  K. Yamaji, T. Kanai, S.M. Nomura, K. Akiyoshi, M. Negishi, Y. Chen, H. Atomi, K. Yoshikawa, T. Imanaka
- Journal Title
  
  IEEE Trans. NanoBioscience 8(4)
  
  Pages: 325-331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17076009
[Journal Article] Application of Laser Manipulation for Evaluating the Antibacterial Effect and for Controlling DNA Conformation2008
- Author(s)
  Y. Yoshikawa
- Journal Title
  
  Proceeding of 2008 International Symposium on Micro-Nanomechatronics and Human Science
  
  Pages: 329-332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20034056
[Journal Article] DNA Compaction Plays a Key Role in Radioprotection against Double-Strand Breaks as Revealed by Single-Molecule Observation2008
- Author(s)
  Y. Yoshikawa
- Journal Title
  
  Chem. Phys. Lett. 456
  
  Pages: 80-83
- NAID
  130006999678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17510102
[Journal Article] DNA Compaction Plays a Key Role in Radioprotection against Double-Strand Breaks as Revealed by Single-Molecule Observation2008
- Author(s)
  Y. Yoshikawa
- Journal Title
  
  Chem. Phys. Lett 456
  
  Pages: 80-83
- NAID
  130006999678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20034056
[Journal Article] DNA Compaction Plays a Key Role in Radioprotection against Double-Strand Breaks as Revealed by Single-Molecule Observation2008
- Author(s)
  Y. Yoshikawa, T. Mori, N. Magome, K. Hibino, K. Yoshikawa
- Journal Title
  
  Chem. Phys. Lett. 456
  
  Pages: 80-83
- NAID
  130006999678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17510102
[Journal Article] DNA二重鎖切断反応の可視化:ビタミンCによる抑制効果の定量的計測2007
- Author(s)
  吉川祐子
- Journal Title
  
  ビタミン 81
  
  Pages: 297-302
- NAID
  110006368520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17510102
[Journal Article] Photo-Induced DNA Double-Strand Breaks Monitored by Single-Molecule Observation : Protective Effect of Antioxidative Compounds2007
- Author(s)
  Y. Yoshikawa, E. Hirose, E. Sakai, C. Ikawa
- Journal Title
  
  Proceeding of 2007 International Symposium on Micro-Nanomehatronics and Human Science (MHS2007)
  
  Pages: 276-280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17510102
[Journal Article] DNA二重鎖切断反応の可視化 : ビタミンCによる抑制効果の定量的計測2007
- Author(s)
  吉川祐子
- Journal Title
  
  ビタミン 81
  
  Pages: 297-302
- NAID
  110006368520
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17510102
[Journal Article] 自己組織化するDNA2007
- Author(s)
  吉川祐子
- Journal Title
  
  現代化学 431
  
  Pages: 14-19
- NAID
  40015255682
- Data Source
  KAKENHI-PROJECT-17510102
[Journal Article] グルメの世界"を科学する2007
- Author(s)
  吉川研一、吉川祐子
- Journal Title
  
  化学工学 71巻31-33
  
  Pages: 0-0
- NAID
  10018666337
- Data Source
  KAKENHI-PROJECT-17510102
[Journal Article] 自己組織化するDNA2007
- Author(s)
  吉川祐子、吉川研一
- Journal Title
  
  現代化学 2月号 No.431
  
  Pages: 14-19
- NAID
  40015255682
- Data Source
  KAKENHI-PROJECT-17510102
[Journal Article] Photo-induced DNA double-strand breaks monitored by single-molecule observation:protective effect of antioxidative compounds2007
- Author(s)
  Yuko Yoshikawa
- Journal Title
  
  Proc.of the 2007 Int'1 Symp.on Micro-Nano Mechatronics and Human Science
  
  Pages: 276-280
- Data Source
  KAKENHI-PROJECT-17510102
[Journal Article] Protective Effect of Vitamin C against Double-Strand Breaks in Reconstituted Chromatin Visualized by Single-Molecule Observation2006
- Author(s)
  Y.Yoshikawa
- Journal Title
  
  Biophys.J. 90
  
  Pages: 993-999
- NAID
  120000896373
- Data Source
  KAKENHI-PROJECT-17510102
[Journal Article] Protective Effect of Vitamin C against Double-Strand Breaks in Reconstituted Chromatin Visualized by Single-Molecule Observation2006
- Author(s)
  Y. Yoshikawa, K. Hizume, Y. Oda, K. Takeyasu, S. Araki, K. Yoshikawa
- Journal Title
  
  Biophys. J. 90
  
  Pages: 993-999
- NAID
  120000896373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17510102
[Journal Article] Quantitative analysis of double-strand break in giant DNA by single-molecule observation2006
- Author(s)
  Y.Yoshikawa
- Journal Title
  
  Proc. XIII Congress of the Society for Free Radical Research International-SFRR 2006
  
  Pages: 341-344
- Data Source
  KAKENHI-PROJECT-17510102
[Journal Article] Quantitative analysis of double-strand break in giant DNA by single-molecule observation2006
- Author(s)
  Y. Yoshikawa, T. Mori, K. Yoshikawa
- Journal Title
  
  Proc. XIII Congress of the Society for Free Radical Research International ed. In Medimond International Proceedings
  
  Pages: 341-344
- Data Source
  KAKENHI-PROJECT-17510102
[Journal Article] Na+ More Strongly Inhibits DNA Compaction by Spermidine (3+) than K^+2006
- Author(s)
  K. Hibino, Y. Yoshikawa, S. Murata, T. Saito, A. A. Zinchenko, K. Yoshikawa
- Journal Title
  
  Chem. Phys. Lett. 426
  
  Pages: 405-409
- NAID
  120000896364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17510102
[Journal Article] Cell-free protein synthesis at high temperatures using the lysate of a hyperthermophile2006
- Author(s)
  T.Endoh, T.Kanai, Y.T.Sato, D.V.Liu, K.Yoshikawa, H.Atomi, T.Imanaka
- Journal Title
  
  J.Biotechnol. 126・2
  
  Pages: 186-195
- Data Source
  KAKENHI-PROJECT-17076009
[Journal Article] Morphological Variation in a Toroid Generated from a Single Polymer Chain2005
- Author(s)
  Y. Takenaka, K. Yoshikawa, Y. Yoshikawa, Y. Koyama, T. Kanbe
- Journal Title
  
  J. Chem. Phys. 123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17510102
[Journal Article] Large Conformational Change on Giant DNA Induced by Ascorbic Acid : A Nobel Scheme on Its Antioxidative Activity2005
- Author(s)
  Y.Yoshikawa
- Journal Title
  
  J.Biotech. 118
- Data Source
  KAKENHI-PROJECT-17510102
[Journal Article] On/Off Switching of Transcription Caused by Folding Transition in Giant DNA : Novel Scenario on Genetic Control2005
- Author(s)
  K.Yoshikawa
- Journal Title
  
  J.Biotech. 118
- Data Source
  KAKENHI-PROJECT-17510102
[Journal Article] Double-Strand Break of Giant DNA : Protection by Glucosyl-Hesperidin as Evidenced Through Direct Observation on Individual DNA Molecules2004
- Author(s)
  Y.Yoshikawa et al.
- Journal Title
  
  FEBS Lett. 566
  
  Pages: 39-42
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14598005
[Journal Article] Double-strand break of giant DNA : protection by glucosyl-hesperidin as evidenced through direct observation on individual DNA molecules2004
- Author(s)
  Yuko Yoshikawa
- Journal Title
  
  FEBS Lett. 566
  
  Pages: 39-42
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14598005
[Journal Article] Ascorbic Acid Induces a Marked Conformational Change in Long Duplex DNA2003
- Author(s)
  Y.Yoshikawa, et al.
- Journal Title
  
  Eur.J.Biochem. 270
  
  Pages: 3101-3106
- NAID
  110004499417
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14598005
[Journal Article] 巨大DNA分子の折り畳み転移:高次構造と機能2003
- Author(s)
  吉川祐子
- Journal Title
  
  放射線生物研究 38
  
  Pages: 335-347
- NAID
  40006070122
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14598005
[Journal Article] Ascorbic acid induces a marked conformational change in long duplex DNA2003
- Author(s)
  Yuko Yoshikawa
- Journal Title
  
  Eur.J.Biochem. 270
  
  Pages: 3101-3106
- NAID
  110004499417
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14598005
[Journal Article] Daunomycin Triggers Membrane Blebbing and Breakage of Giant DNA Encapsulated in a Cell-Sized Liposome2002
- Author(s)
  Y.Yoshikawa at al.
- Journal Title
  
  Chem.Phys.Lett. 366
  
  Pages: 305-310
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14598005
[Journal Article] All-or-None Folding Transition in Giant Mammalian DNA2002
- Author(s)
  K.Yoshikawa et al.
- Journal Title
  
  Chem.Phys.Lett. 354
  
  Pages: 354-359
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14598005
[Journal Article] DNAの高次構造スイッチングと遺伝子発現2002
- Author(s)
  吉川祐子
- Journal Title
  
  生物物理 42
  
  Pages: 179-184
- NAID
  110001155776
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14598005
[Journal Article] Daunomycin triggers membrane blebbing and breakage of giant DNA encapsulated in a cell-sized liposome2002
- Author(s)
  Yuko Yoshikawa
- Journal Title
  
  Chem.Phys.Lett. 366
  
  Pages: 305-310
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14598005
[Journal Article] All-or-none folding transition in giant mammalian DNA2002
- Author(s)
  Kenichi Yoshikawa
- Journal Title
  
  Chem.Phys.Lett. 354
  
  Pages: 354-359
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14598005
[Presentation] 顕著な抗腫瘍効果を有する白金(II)二核錯体のユニークな作用機構2017
- Author(s)
  植村雅子、米田誠治、吉川研一、吉川祐子、春沢信哉、米山弘樹
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台市
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] 制がん白金(II)二核錯体のDNA凝縮能および細胞内取り込みに関する研究2017
- Author(s)
  植村雅子, 米山弘樹, 岡本直人, 村松晃, 福田青郎, 小西宏明, 髙木陽光, 松﨑健, 春沢信哉, 吉川祐子, 今中忠行, 吉川研一，米田誠治
- Organizer
  第63回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] Structure-activity relationships, DNA compaction efficiencies and intracellular accumulations on anticancer-active tetrazolato-bridged dinuclear platinum(II) complexes2017
- Author(s)
  Komeda, S.; Uemura, M.; Hiramoto, K.; Yoshikawa, Y.; Yoshikawa, K.; Yoneyama, H.; Harusawa, S.
- Organizer
  14th International Symposium on Applied Bioinorganic Chemistry
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] 長短鎖アルキル基を導入した制がんテトラゾラト架橋白金(II)二核錯体の細胞内取込およびDNA凝縮能2016
- Author(s)
  米田誠治, 植村雅子, 米山弘樹, 岡本直人, 村松晃, 福田青郎, 小西宏明, 髙木陽光, 松﨑健, 春沢信哉, 吉川祐子, 今中忠行, 吉川研一
- Organizer
  日本薬学会第136年会横浜市年月日201603-201603
- Place of Presentation
  横浜市
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] Biological efficiency of anticancer tetrazolato-bridged dinuclear platinum(II) complexes with different length of alkyl substituent in relation to the structural effect of DNA2016
- Author(s)
  Komeda, S.; Uemura, M.; Yoneyama, H.; Muramatsu, A.; Okamoto, N.; Harusawa, S.; Yoshikawa, Y.; Yoshikawa, K.
- Organizer
  金属の関与する生体関連反応シンポジウム (SRM2016)
- Place of Presentation
  札幌市
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] Significant effect of dinuclear Pt(II) complexes on the higher-order structure of genomic DNA2016
- Author(s)
  Shimizu, Y.; Yoshikawa, Y.; Uemura, M.; Kenmotsu, T.; Komeda, S.; Yoshikawa, K.
- Organizer
  8th Asian Biological Inorganic Chemistry Conference
- Place of Presentation
  ニュージーランド　オークランド
- Year and Date
  2016-12-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] Solid-phase synthesis of structurally diverse polyamines and specificity on their interaction with DNA duplex2016
- Author(s)
  Naoki Umezawa, Yuhei Horai, Yuki Imamura, Akira Muramatsu, Kenichi Yoshikawa, Yuko Yoshikawa, Tsunehiko Higuchi
- Organizer
  The 8th Takeda Science Foundation Symposium on PharmaSciences, Biomolecule-Based Medicinal Science: Featuring Mid-Size Drugs
- Place of Presentation
  Center for Learning and Innovation Takeda Pharmaceutical Company Ltd.
- Year and Date
  2016-01-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08027
[Presentation] 多様なポリアミンの固相合成とDNA二重鎖に及ぼす影響2015
- Author(s)
  梅澤直樹、寳来侑平、今村優希、辻佳寿美、村松晃、吉川研一、吉川祐子、加藤信樹、樋口恒彦
- Organizer
  第9回バイオ関連化学シンポジウム
- Place of Presentation
  熊本大学工学部　黒髪南キャンパス
- Year and Date
  2015-09-10
- Data Source
  KAKENHI-PROJECT-15K08027
[Presentation] Action of novel anticancer-active, dinuclear platinum complexes with ester group on the higher order structure and genomic activity of DNA2015
- Author(s)
  Shimizu, Y; Yoshikawa, Y; TaTsuchiya, T; Hiroki Yoneyama, H; Harusawa, S; Komeda, S; Imanaka, T; Kenmotsu, T; Yoshikawa, K.
- Organizer
  第53回生物物理学会日本薬学会
- Place of Presentation
  金沢市
- Year and Date
  2015-09-13
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] Cellular uptake and DNA compaction of anticancer tetrazolato-bridged dinuclear platinum(II) complexes with various substituents at tetrazole C52015
- Author(s)
  Uemura, M; Yoneyama, H; Yoshikawa, T; Tsuchiya, T; Hoshiyama, M; Sato, T; Yoshikawa, K; Harusawa, S; Komeda, S
- Organizer
  第25回金属の関与する生体関連反応シンポジウム
- Place of Presentation
  長崎市
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] Cellular uptake and DNA compaction of anticancer tetrazolato-bridged dinuclear platinum(II) complexes with various substituents at tetrazole C52015
- Author(s)
  Uemura, M; Yoneyama, H; Yoshikawa, T; Tsuchiya, T; Hoshiyama, M; Sato, T; Yoshikawa, K; Harusawa, S; Komeda, S
- Organizer
  1st International Symposium on Clinical and Experimental Metallodrugs in Medicine: Cancer Chemotherapy
- Place of Presentation
  米国ハワイ州
- Year and Date
  2015-12-13
- Data Source
  KAKENHI-PROJECT-15K07905
[Presentation] 超好熱菌由来の分岐型ポリアミンが引き起こすゲノムDNAの特異な高次構造変化2014
- Author(s)
  村松晃, 吉川祐子, 福田青郎, 藤原伸介, 梅澤直樹, 神戸俊夫, 今中忠行, 吉川研一
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県）
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-25390038
[Presentation] Chiral preference of tetravalent polyamines in DNA compaction2013
- Author(s)
  Y. Yoshikawa1, N. Umezawa, Y. Imamura, T. Kanbe, N. Kato, K. Yoshikawa, T. Imanaka, T. Higuch
- Organizer
  The International Conference on Medical Physics
- Place of Presentation
  Brighton, UK
- Data Source
  KAKENHI-PROJECT-25390038
[Presentation] Single molecule real-time observation of DNA interacting with dinuclear platinum antitumordrugs2012
- Author(s)
  Yuko Yoshikawa
- Organizer
  XXIInd International Symposium on Medicinal Chemistry
- Place of Presentation
  Berlin(Germany)
- Year and Date
  2012-09-03
- Data Source
  KAKENHI-PROJECT-22510123
[Presentation] Direct observation of large-scale conformational transition in megabase-size DNA2011
- Author(s)
  Yuko Yoshikawa
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜神奈川県
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22510123
[Presentation] Real-time observation of platinum anticancer drug-DNA interactions at the single-molecule level2011
- Author(s)
  Yuko Yoshikawa
- Organizer
  12th Conference on Methods and Applications of Fluorescence Spectroscopy, Imaging and Probes
- Place of Presentation
  Strasbourg FRANCE
- Year and Date
  2011-09-11
- Data Source
  KAKENHI-PROJECT-22510123
[Presentation] Direct observation of large-scale conformational transitionin megabase-size DNA2011
- Author(s)
  Yuko Yoshikawa
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22510123
[Presentation] Real-time observation of platinum anticancer drug-DNA interactions at the single-molecule level2011
- Author(s)
  Yuko Yoshikawa
- Organizer
  12th Conference on Methods and Applications of Fluorescence Spectroscopy,Imaging and Probes
- Place of Presentation
  Strasbourg(France)
- Year and Date
  2011-09-11
- Data Source
  KAKENHI-PROJECT-22510123
[Presentation] 単一分子観察法を用いたアスコルビン酸-2グルコシドによるDNA二重鎖切断抑制作用の評価2010
- Author(s)
  吉川祐子
- Organizer
  第131回ビタミンC研究員会
- Place of Presentation
  お茶の水女子大学(東京都)
- Year and Date
  2010-03-13
- Data Source
  KAKENHI-PROJECT-20034056
[Presentation] 抗がん剤-DNA相互作用のリアルタイム計測:単一分子観察法の活用2010
- Author(s)
  吉川祐子
- Organizer
  日本環境変異原学会第39回大会
- Place of Presentation
  つくば国際会議場(茨城県)
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-22510123
[Presentation] DNAの高次構造と放射線感受性:単一分子観察法による定量的評価2010
- Author(s)
  吉川祐子
- Organizer
  第8回特定領域「バイオ操作」公開シンポジウム
- Place of Presentation
  九州大学(福岡県)
- Year and Date
  2010-03-11
- Data Source
  KAKENHI-PROJECT-20034056
[Presentation] 光およびガンマ線によるDNA二重鎖切断の定量解析:水溶性フラボノイドによる保護作用2010
- Author(s)
  吉川祐子
- Organizer
  日本放射線影響学会第53回大会
- Place of Presentation
  京都テルサ(京都府)
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-22510123
[Presentation] Higher Order Structure of Giant DNA and Radiosensitivity2010
- Author(s)
  Yuko Yoshikawa
- Organizer
  The 1421st Biological Symposium
- Place of Presentation
  国立遺伝研(静岡県)
- Year and Date
  2010-04-22
- Data Source
  KAKENHI-PROJECT-22510123
[Presentation] DNAの高次構造と放射線感受性2010
- Author(s)
  吉川祐子
- Organizer
  生理学研究所研究会「DNAの凝縮:物理から生理まで」
- Place of Presentation
  自然科学研究機生理学研究所(岡崎市)
- Year and Date
  2010-03-10
- Data Source
  KAKENHI-PROJECT-20034056
[Presentation] Single DNA Observation to Evaluate the Kinetics of Double-Strand Break2010
- Author(s)
  Yuko Yoshikawa
- Organizer
  ICS/JSPS Joint Seminar : Confinement of DNAs and Biofilaments
- Place of Presentation
  Strasbourg, (France)
- Year and Date
  2010-12-21
- Data Source
  KAKENHI-PROJECT-22510123
[Presentation] DNA高次構造の多様性と二重鎖切断:単分子観察法による定量的解析2009
- Author(s)
  吉川祐子
- Organizer
  変異機構研究会第22回夏の学校
- Place of Presentation
  愛知県小牧勤労センター(愛知県)
- Year and Date
  2009-06-20
- Data Source
  KAKENHI-PROJECT-20034056
[Presentation] Controlling the Higher Order Strucutre of DNA-Protamine Complex2009
- Author(s)
  吉川祐子
- Organizer
  20^<th> IEEE International Symposium on Micro-Nanomechatronics and Human Science(MHS2009)
- Place of Presentation
  名古屋大学(名古屋市)
- Year and Date
  2009-11-09
- Data Source
  KAKENHI-PROJECT-20034056
[Presentation] Giant DNA in Water : Conformational transition and radiosensitivity2009
- Author(s)
  吉川祐子
- Organizer
  Forth Annual Conference on the Physics, Chemistry and Biology of Water
- Place of Presentation
  Mount Snow(米国)
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20034056
[Presentation] Conformational Transition of Large DNA and Its Environmental Response2009
- Author(s)
  吉川祐子
- Organizer
  The First World Congress of International Academy of Nanomedicine
- Place of Presentation
  海南島(中国)
- Year and Date
  2009-06-12
- Data Source
  KAKENHI-PROJECT-20034056
[Presentation] アスコルビン酸グルコシドによって引き起こされるDNAの高次構造変化2009
- Author(s)
  吉川祐子
- Organizer
  第130回ビタミンC研究委員会
- Place of Presentation
  奈良女子大学(奈良県)
- Year and Date
  2009-11-07
- Data Source
  KAKENHI-PROJECT-20034056
[Presentation] DNAの折り畳み構造と二重鎖切断:単一分子観察法による定量的解析2009
- Author(s)
  吉川祐子
- Organizer
  特定領域「バイオ操作」第2回女性研究者シンポジウム「分野横断的手法を活用した新時代の生命科学研究」
- Place of Presentation
  東京大学山上会館(東京都)
- Year and Date
  2009-08-18
- Data Source
  KAKENHI-PROJECT-20034056
[Presentation] Higher Order Structure of DNA and Its Environmental Response2009
- Author(s)
  Y. Yoshikawa
- Organizer
  Invited Lecture at ENS de Cachan
- Place of Presentation
  Cachan(フランス)
- Year and Date
  2009-02-23
- Data Source
  KAKENHI-PROJECT-20034056
[Presentation] Higher Order Structure of DNA and Its environmental Response2009
- Author(s)
  吉川祐子
- Organizer
  Physics Goes DNA : From Base-Pair to Chromatin
- Place of Presentation
  Leiden Univ.(オランダ)
- Year and Date
  2009-09-11
- Data Source
  KAKENHI-PROJECT-20034056
[Presentation] ゲノムDNAの高次構造と生命機能 : 折り畳み構造の多様性と二重鎖切断2008
- Author(s)
  吉川祐子
- Organizer
  マルチスケール操作によるシステム細胞工学学術講演会
- Place of Presentation
  高松(香川)
- Year and Date
  2008-12-04
- Data Source
  KAKENHI-PROJECT-20034056
[Presentation] DNA compaction plays a key role in protection against double-strand break as revealed by single-molecule observation2008
- Author(s)
  Yuko Yoshikawa
- Organizer
  Gordon Research Conference: DNA Damage, Mutation&Cancer
- Place of Presentation
  Ventura,CA,USA
- Year and Date
  2008-03-12
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] プロタミンによるDNAの高次構造変化と放射線保護作用 : 単一分子観察法の活用2008
- Author(s)
  吉川祐子
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸(兵庫)
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-20034056
[Presentation] 長鎖DNAの二重鎖切断を指標とした抗酸化能の定量的解析 : アスコルビン酸と他の抗酸化物質との比較検討へ向けて2008
- Author(s)
  吉川祐子
- Organizer
  ビタミンC研究委員会
- Place of Presentation
  東京
- Year and Date
  2008-07-05
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] Higher Order Structure of DNA is One of the Decisive Factors for Radiosensitivity2008
- Author(s)
  Y. Yoshikawa
- Organizer
  International Nanomedicine Symposium
- Place of Presentation
  北京(中国)
- Year and Date
  2008-10-20
- Data Source
  KAKENHI-PROJECT-20034056
[Presentation] DNA compaction plays a key role in protection against double-strand break as revealed by single-molecule observation2008
- Author(s)
  Y. Yoshikawa
- Organizer
  Gordon Research Conference : DNA Damage, Mutation & Cancer
- Place of Presentation
  Ventura, CA, USA
- Year and Date
  2008-03-09
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] Application of Laser Manipulation for Evaluating the Antibacterial Effect and for Controlling DNA Conformation2008
- Author(s)
  Y. Yoshikawa
- Organizer
  19^<th> IEEE International Symposium on Micro-Nanomechatronics and Human Science (MHS2008)
- Place of Presentation
  名古屋(愛知)
- Year and Date
  2008-11-06
- Data Source
  KAKENHI-PROJECT-20034056
[Presentation] Radiation-induced double-strand break of giant DNA and its protection by antioxidative compounds2007
- Author(s)
  Y. Yoshikawa
- Organizer
  第1回アジア環境変異原学会・日本環境変異原学会第36回大会
- Place of Presentation
  北九州
- Year and Date
  2007-11-19
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] Quantitative analysis of double-strand breaks in reconstituted chromatin by single-molecule observation2007
- Author(s)
  Yuko Yoshikawa
- Organizer
  16th International Chromosome Conference
- Place of Presentation
  Amsterdam,Netherland
- Year and Date
  2007-08-27
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] Quantitative analysis of double-strand breaks in reconstituted chromatin by single-molecule observation2007
- Author(s)
  Y. Yoshikawa
- Organizer
  16^<th> International Chromosome Conference
- Place of Presentation
  Amsterdam, the Netherlands
- Year and Date
  2007-08-25
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] 放射線による長鎖DNA二重鎖切断の新計測手法:糖付加水溶性ルチンおよびヘスペリジンによる抑制作用の定量的評価2007
- Author(s)
  吉川祐子
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] 放射線照射による長鎖DNAの二重鎖切断と糖転移ルチンおよびヘスペリジンによる抑制作用2007
- Author(s)
  吉川祐子
- Organizer
  日本ビタミン学会第59回大会
- Place of Presentation
  佐世保
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] Photo-induced DNA double-strand breaks monitored by single-molecule observation:protective effect of antioxidative compounds2007
- Author(s)
  Yuko Yoshikawa
- Organizer
  18th IEEE International Symposium on Micro-Nano mechatronics and Human Science(MHS2007)
- Place of Presentation
  名古屋
- Year and Date
  2007-11-12
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] 放射線による長鎖DNA二重鎖切断の新計測手法 : 糖付加水溶性ルチンおよびヘスペリジンによる抑制作用の定量的評価2007
- Author(s)
  吉川祐子
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] 単一分子観察法を用いた長鎖DNAの二重鎖切断反応の速度論的解析2007
- Author(s)
  吉川祐子
- Organizer
  核酸を中心としたケミカルバイオロジー
- Place of Presentation
  京都
- Year and Date
  2007-03-17
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] Photo-Induced DNA Double-Strand Breaks Monitored by Single-Molecule Observation : Protective Effect of Antioxidative Compounds2007
- Author(s)
  Y. Yoshikawa
- Organizer
  18^<th> IEEE International Symposium on Micro-Nanomechatronics and Human Science (MHS2007)
- Place of Presentation
  名古屋
- Year and Date
  2007-11-12
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] Direct visualization of double-strand breaks in reconstituted chromatin and the protective effect of ascorbic acid2006
- Author(s)
  Y. Yoshikawa
- Organizer
  Workshop on Driven States in Soft and Biological Matter
- Place of Presentation
  Trieste, Italy
- Year and Date
  2006-04-24
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] 再構成クロマチンを用いた二本鎖切断反応の可視化とアスコルビン酸による抑制作用2006
- Author(s)
  吉川祐子
- Organizer
  日本ビタミン学会第58回大会
- Place of Presentation
  徳島
- Year and Date
  2006-05-27
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] Protective activity of vitamin C against double-strand breaks in reconstituted chromatin revealed by single-molecule observation2006
- Author(s)
  Y. Yoshikawa
- Organizer
  13th Biennial Congress of the International Society for Free Radical Research
- Place of Presentation
  Davos, Switzerland
- Year and Date
  2006-08-15
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] DNA高次構造の自己組織化と生物活性2006
- Author(s)
  吉川祐子
- Organizer
  生理学研究所研究会「DNA構造を基盤とするゲノム生理学の展開-DNA,蛋白質、膜の相互作用」
- Place of Presentation
  岡崎
- Year and Date
  2006-11-09
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] ビタミンCによるDNA二重鎖切断の抑制 : 単一分子観察法による定量的解析2006
- Author(s)
  吉川祐子
- Organizer
  ビタミンC研究委員会
- Place of Presentation
  和歌山
- Year and Date
  2006-10-07
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] Observation and Manipulation of Individual DNA Molecules : Unraveling the Intrinsic Property of Giant DNA2005
- Author(s)
  Y. Yoshikawa
- Organizer
  Bio-Soft Matter Days 2005
- Place of Presentation
  台北、台湾
- Year and Date
  2005-12-19
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] DNAの高次構造変化と二本鎖切断反応-1分子可視化法の活用2005
- Author(s)
  吉川祐子
- Organizer
  放射線施設共同利用報告会
- Place of Presentation
  堺
- Year and Date
  2005-06-27
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] アスコルビン酸によって引き起こされるゲノムDNAの高次構造変化と抗酸化作用2005
- Author(s)
  吉川祐子
- Organizer
  日本ビタミン学会第57回大会
- Place of Presentation
  志摩
- Year and Date
  2005-05-26
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] Marked Structural Chamge on Giant DNA Induced by Ascorbic Acid : Nobel Scheme on Its Antioxidant Activity2005
- Author(s)
  Y. Yoshikawa
- Organizer
  Human Genome Meeting 2005
- Place of Presentation
  京都
- Year and Date
  2005-04-18
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] 単一分子鎖観察法による再構成クロマチンでの二本鎖切断反応の定量的解析 : アスコルビン酸による抑制作用2005
- Author(s)
  吉川祐子
- Organizer
  第34回日本環境変異原学会
- Place of Presentation
  東京
- Year and Date
  2005-11-16
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] DNAの高次構造制御 : 非ウィルスベクターの設計への応用2005
- Author(s)
  吉川祐子
- Organizer
  遺伝子・デリバリー研究会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2005-05-21
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] Large Conformational Change on Giant DNA Induced by Ascorbic Acid : A Nobel Scheme on Its Antioxidative Activity2005
- Author(s)
  Y. Yoshikawa
- Organizer
  The 12^<th> European Congress on Biotechnology
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2005-08-21
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] 再構成クロマチンにおける二本鎖切断反応の可視化とアスコルビン酸による抑制作用の定量的解析 : 単一分子鎖観察法の活用2005
- Author(s)
  吉川祐子
- Organizer
  第28回日本分子生物学会
- Place of Presentation
  福岡
- Year and Date
  2005-12-07
- Data Source
  KAKENHI-PROJECT-17510102
[Presentation] キラルなポリアミン類によるゲノムDNA分子の高次構造制御：キラル認識に基づく凝縮能の違い
- Author(s)
  吉川祐子
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡マリンメッセ、福岡県
- Data Source
  KAKENHI-PROJECT-22510123
[Presentation] Structural changes of DNA induced by antitumor tetrazolato-bridged dinuclear platinum(II) complexes with different alkyl chain lengths
- Author(s)
  Y. Yoshikawa, A. Muramatsu, S. Komeda, W. Fukuda, T. Kanbe, K. Yoshikawa, T. Imanaka
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県）
- Data Source
  KAKENHI-PROJECT-25390038
[Presentation] Single molecule real-time observation of DNA interacting with dinuclear platinum antitumor drugs
- Author(s)
  Yuko Yoshikawa
- Organizer
  XXIInd International Symposium on Medicinal Chemistry
- Place of Presentation
  Berlin (Germany)
- Data Source
  KAKENHI-PROJECT-22510123

1. IMANAKA Tadayuki (30029219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. KANAI Tamotsu (10346083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. Komeda Seiji (60425056)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
4. HIRAMOTO Keiichi (90251793)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. HARUSAWA Shinya (90167601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
6. YONEYAMA Hiroki (90627001)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
7. Umezawa Naoki (40347422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. YOSHIKAWA Kenichi (80110823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. UMEHARA Takashi (20415095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. INOUE Katsuhisa (50315892)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 植村雅子 (70511997)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
12. 藤原伸介

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 前島一博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 瀧口金吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 林真人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 市川正敏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YOSHIKAWA Yuko 吉川 祐子

Research Projects

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Co-Researchers

Drug discovery research based on dinuclear platinum complexes with markedly high antitumor activity

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Conformationally restricted polyamines: Solid-phase synthesis and biological evaluation

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Controlling the higher-order structure of genomic DNA in relation to its genetic activityPrincipal Investigator

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Controlling the higher order structure of single DNA molecule with attention to environmental stressPrincipal Investigator

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DNAの高次構造変化と環境応答:その場操作の活用Principal Investigator

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Development of a genome-scale in vitro transcription and translation-coupled system

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pplication of Single-Molecule Observation for Kinetic Analysis of Genomic DNA Double-Strand Breaks in Relation to Genetic ActivityPrincipal Investigator

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Dynamical Structural Change of Reconstituted Chromatin and Its Genetic ActivityPrincipal Investigator

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Morphological Variation of Higher Order Structure of Long Duplex DNA and its genetic activityPrincipal Investigator

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[Book] 『栄養・食糧学用語辞典』日本栄養・食糧学会編(項目分担 : 総著者数283名)2007

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[Book] "Physical Chemistry of DNA-Carrier Complex" in Non-viral Gene Therapy : Gene Design and Delivery(Eds. K. Taira, K. Kataoka, T. Niidome)2005

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[Book] Non-viral Gene Therapy : Gene Design and Delivery2005

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[Journal Article] Specific Conformational Change in Giant DNA Caused by Anticancer2017

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[Journal Article] Conformational transition of DNA by dinuclear Pt(II) complexes causes cooperative inhibition of gene expression2017

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YOSHIKAWA Yuko 吉川祐子