AKAMATSU Tetsuya 赤松徹也

Researcher Number	80294700
Other IDs
Affiliation *help	2016 – 2018 : 徳島大学, 大学院生物資源産業学研究部, 准教授 2016 – 2018 : 徳島大学, 大学院社会産業理工学研究部(生物資源産業学域), 准教授 2015 : 徳島大学, 大学院医歯薬学研究部, 准教授 2011 – 2014 : 徳島大学, ヘルスバイオサイエンス研究部, 准教授 2011 : 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 准教授 … More
Review Section/Research Field	Principal Investigator Functional basic dentistry / Functional basic dentistry Except Principal Investigator Functional basic dentistry / Functional basic dentistry / Metabolomics
Keywords	Principal Investigator 顎下腺 / PACE4 / AQP5 / 水チャネル / bHLH型転写因子 / サチライシン様前駆体蛋白質変換酵素 / 分枝形成 / 骨形成蛋白質 / 口腔組織 / 腺房細胞 … More Except Principal Investigator 唾液腺 / トラフィッキング / アクアポリン / LPS / aquaporins / Brunner's gland / ブルナー腺 / salivary gland / duodenum / 十二指腸 / 炎症性サイトカイン / trafficking / endosome / SDラット / 幹細胞特異抗原 / 消化管 / 遺伝的変動 / マウス / gastrointestinal tract / カルシウム / Salivary gland / Proreninn converting enzyme / カリクレインmK13 / GFP-AQP5キメラ分子 / カテプシン / 真性組織カリクレイン / True tissue kallikrein / プロセッシング / pancreatic islet β cells / プロセシング酵素 / Kininogen / 膵β細胞 / 組織カリクレインファミリー / 遺伝子変異 / 成長因子 / Sprague-Dawley rat / Submandibular gland / Acute phase protein / 外分泌腺 / プロレニン / 塩酸セビメリン / 鼓索神経切除 / Inflammation cytokine / in vivoイメージング / 急性期蛋白質 / セリンプロテアーゼ / genetic variation / 副交感神経 / Processing enzyme / 薬理学 / バイオテクノロジー / ウイルスベクター / Tissue kallikrein family / exocrine gland / 組織カリクレイン / IL-1β / 細胞内カルシウムイオン / VIP / アクアポリン5 / 生理学 / TLR4 / キニノーゲン / プロレニン変換酵素 / エンドソーム / Mouse / serine protease / 細胞骨格 / MDCK細胞 Less

唾液腺Ca2+応答の低侵襲的長期間イメージング技術の確立と機能・再生研究Ongoing
- Principal Investigator
  
  谷村明彦
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Health Sciences University of Hokkaido
Elucidation of Molecular Mechanism of the Salivary Gland Regeneration ~ Toward the application to the Regenerative Medicine for Xerostomia ~Principal Investigator
- Principal Investigator
  
  Akamatsu Tetsuya
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  The University of Tokushima
病態時における外分泌腺型水チャネル、AQP5の発現と機能調節の分子機構
- Principal Investigator
  
  細井和雄
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  The University of Tokushima
Elucidation of the molecular mechanism on the differentiation/maturation and functional expression of salivary acinar cell toward conquest of xerostomia.Principal Investigator
- Principal Investigator
  
  AKAMATSU Tetsuya
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  The University of Tokushima
Moecular meohanism of expression and regulation of the water channe1, aquapor in 5 in the exocrine gland
- Principal Investigator
  
  HOSOI Kazuo
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  The University of Tokushima
唾液腺腺房細胞の分化誘導、及び機能発現の分子メカニズムの解明Principal Investigator
- Principal Investigator
  
  赤松徹也
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  The University of Tokushima
唾液腺における炎症性サイトカインの誘導と口腔の防御システム:再生医療への試み
- Principal Investigator
  
  HOSOI Kazuo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  The University of Tokushima
水チャネル,アクアポリンの唾液腺発生過程における発現・局在及び機能制御機構の解明Principal Investigator
- Principal Investigator
  
  赤松徹也
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  The University of Tokushima
Characterization of β cell-specific gene obtained by large cDNA sequencing.
- Principal Investigator
  
  YOSHIMOTO Katsuhiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokushima
Inflammation by mast cell kininogen and its suppression -Development of a new drug
- Principal Investigator
  
  HOSOI Kazuo
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  The University of Tokushima
Molecular mechanisms of expression and regulation of water channel proteins aquaporins in the exocrine gland cells
- Principal Investigator
  
  HOSOI Kazuo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  The University of Tokushima
歯・唾液腺発生過程でのプロセシング酵素PACE4の発現制御機構及び生理機能の解明Principal Investigator
- Principal Investigator
  
  赤松徹也
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  The University of Tokushima
Molecular mechanisms of expression and regulation of function of water channel proteins aquaporins in the salivary gland cells
- Principal Investigator
  
  KAZUO Hosoi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  University of Tokushima
口腔組織(歯,舌,唾液腺)発生におけるサチライシン様プロ蛋白質変換酵素の役割Principal Investigator
- Principal Investigator
  
  赤松徹也
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Functional basic dentistry
- Research Institution
  The University of Tokushima
A new physiologic function of tissue kallikrein family enzymes and processing of growth factor precursors
- Principal Investigator
  
  HOSOI Kazuo
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  THE UNIVERSITY OF TOKUSHIMA,SCHOOL OF DENTISTRY

All 2016 2015 2014 2013 2009 2008 2007 2006

All Journal Article Presentation Book

[Book] 動物細胞培養の手法と細胞死・増殖不良・細胞変異を防止する技術(第9章12節唾液腺研究における組織培養・分化誘導系)2014
- Author(s)
  赤松徹也,姚陳娟,細井和雄
- Publisher
  ㈱技術情報協会
- Data Source
  KAKENHI-PROJECT-23592737
[Book] 動物細胞培養の手法と細胞死・増殖不良・細胞変異を防止する技術（第8節[14]唾液腺研究における組織培養・分化誘導系）2014
- Author(s)
  赤松徹也，姚陳娟，細井和雄
- Publisher
  ㈱技術情報協会
- Data Source
  KAKENHI-PROJECT-23592737
[Book] Neil D. Rawlings and Guy S. Salvesen, editors, Handbook of Proteolytic Enzymes, 3rd Edn. (Chapter 729: Proprotein Convertase PACE4. pp.3299-3305)2013
- Author(s)
  Tetsuya Akamatsu
- Total Pages
  7
- Publisher
  Oxford: Academic Press.
- Data Source
  KAKENHI-PROJECT-23592737
[Book] Neil D. Rawlings and Guy S. Salvesen, editors, Handbook of Proteolytic Enzymes, 3rd Edn2013
- Author(s)
  Tetsuya Akamatsu, Oxford
- Publisher
  Academic Press
- Data Source
  KAKENHI-PROJECT-23592737
[Book] 口腔生物学-各論唾液腺(天野修、草間薫編集)2006
- Author(s)
  細井和雄, 赤松徹也, 他(分担執筆)
- Total Pages
  144
- Publisher
  学建書院
- Data Source
  KAKENHI-PROJECT-16659513
[Book] 口腔生物学-各論唾液腺(天野修、草間薫編集)2006
- Author(s)
  細井和雄, 赤松徹也, 他(分担執筆)
- Total Pages
  144
- Publisher
  学建書院(東京)
- Data Source
  KAKENHI-PROJECT-18390493
[Journal Article] 唾液腺の構造と機能2016
- Author(s)
  赤松徹也
- Journal Title
  
  J Oral Health & Biosci
  
  Volume : 28 Pages : 77-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462814
[Journal Article] 唾液腺再生におけるサチライシン様前駆体蛋白質変換酵素PACE4の関与2013
- Author(s)
  赤松徹也,姚陳娟,長谷川敬展,吉村弘
- Journal Title
  
  J. Oral Biosci
  
  Volume : Suppl Pages : 199-199
- Data Source
  KAKENHI-PROJECT-23592737
[Journal Article] 唾液腺再生におけるサチライシン様前駆体蛋白質変換酵素PACE4の関与2013
- Author(s)
  赤松徹也，姚陳娟，長谷川敬展，吉村弘
- Journal Title
  
  J. Oral Biosci.
  
  Volume : Suppl. Pages : 199-199
- Data Source
  KAKENHI-PROJECT-23592737
[Journal Article] Trafficking of GFP-AQP5 chimeric proteins conferred with unphosphorylated amino acids at their PKA-target motif(152SRRTS) in MDCK-II cells2009
- Author(s)
  Karabasil, M.R., T. Hasegawa, A. Azlina, N. Purwanti, J.Purevjav, C. Yao, T. Akamatsu and K. Hosoi
- Journal Title
  
  The Journal of Medical Investigation 56(1, 2)
  
  Pages : 55-63
- Data Source
  KAKENHI-PROJECT-18390493
[Journal Article] Inhibition and transcriptional silencing of a subtilisin-like proprotein convertase, PACE4/SPC4, reduces the branching morphogenesis of and AQP5 expression in rat embryonic submandibular gland2009
- Author(s)
  Akamatsu, T., A. Azlina, N. Purwanti, M.R. Karabasil, T. Hasegawa, C. Yao, and K. Hosoi
- Journal Title
  
  Developmental Biology 325(2)
  
  Pages : 434-443
- Data Source
  KAKENHI-PROJECT-18390493
[Journal Article] Inhibition and transcriptional silencing of a subtilisin-like proprotein convertase, PACE4/SPC4, reduces the branching morphogenesis of and AQP5 expression in rat embryonic submandibular gland.2009
- Author(s)
  Tetsuya Akamatsu, et al.
- Journal Title
  
  Developmental Biology 325(2)
  
  Pages : 432-441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390493
[Journal Article] Degradation of submandibular gland AQP5 by parasympathetic denervation of chords tympani and its recovery by cevimeline, an M3 muscarinic receptor agonist2008
- Author(s)
  Li X., A. Azlina, M.R. Karabasil, N. Purwanti, T. Hasegawa, C. Yao, T. Akamatsu, and K. Hosoi
- Journal Title
  
  American Journal of Physiology-Gastrointestinal and Liver Physiology 295(1)
  
  Pages : 112-123
- Data Source
  KAKENHI-PROJECT-18390493
[Journal Article] Temporospatially regulated expression of subtilisin-like proprotein convertase PACE4 (SPC4) during development of the rat submandibular gland2007
- Author(s)
  Akamatsu, T. et al.
- Journal Title
  
  Developmental Dynamics 236・1
  
  Pages : 314-320
- Data Source
  KAKENHI-PROJECT-18791369
[Journal Article] Temporospatially regulated expression of subtilisin-like proproteinconvertase PACE4 (SPC4) during development of the rat submandibular gland2007
- Author(s)
  Akamatsu, T., N. Purwanti, M.R. Karabasil, X. Li, C. Yao, N. Kanamori, and K.Hosoi
- Journal Title
  
  Developmental Dynamics 236(1)
  
  Pages : 314-320
- Data Source
  KAKENHI-PROJECT-18390493
[Journal Article] Temporospatially regulated expression of subtilisin-like proproteinconvertase PACE4 (SPC4) during development of the rat submandibular gland2007
- Author(s)
  Akamatsu, T. et al.
- Journal Title
  
  Developmental Dynamics 236(1)
  
  Pages : 314-320
- Data Source
  KAKENHI-PROJECT-18390493
[Journal Article] A naturally occurring point mutation in the rat aquaporin 5 gene, influencing its protein production by and secretion of water from salivary glands2006
- Author(s)
  Murdiastuti, K., N. Purwanti, M.R. Karabasil, X. Li, C. Yao, T. Akamatsu, N. Kanamori, and K. Hosoi
- Journal Title
  
  American Journal of Physiology-Gastrointestinal and Liver Physiology 291(6)
  
  Pages : 1081-1088
- Data Source
  KAKENHI-PROJECT-18390493
[Journal Article] Protein kinase A-regulated membrane trafficking of a green fluorescent protein-aquaporin 5 chimera in MDCK cells2006
- Author(s)
  Kosugi-Tanaka, C., X. Li, C. Yao, T. Akamatsu, N. Kanamori, and K. Hosoi
- Journal Title
  
  Biochimica et Biophysica Acta, Molecular Cell Research 1763(4)
  
  Pages : 337-344
- Data Source
  KAKENHI-PROJECT-18390493
[Presentation] Induced expression of a subtilisin-like proprotein convertase PACE4 in the regeneration model of rat submandibular gland2016
- Author(s)
  Chenjuan Yao, Tetsuya Akamatsu, Takahiro Hasegawa, Hiroshi Yoshimura
- Organizer
  The 4th International Symposium on Salivary Glands in Honor of Niels Stensen
- Place of Presentation
  自然科学研究機構岡崎カンファレンスセンター（愛知県岡崎市）
- Year and Date
  2016-11-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462814
[Presentation] Sexual difference in the regeneration model of the rat submandibular gland2016
- Author(s)
  Tetsuya Akamatsu, Chenjuan Yao, Takahiro Hasegawa, Hiroshi Yoshimura
- Organizer
  The 4th International Symposium on Salivary Glands in Honor of Niels Stensen
- Place of Presentation
  自然科学研究機構岡崎カンファレンスセンター（愛知県岡崎市）
- Year and Date
  2016-11-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462814
[Presentation] 唾液腺再生過程で見られる雌雄差について2016
- Author(s)
  赤松徹也，姚陳娟，長谷川敬展，吉村弘
- Organizer
  第58回歯科基礎医学会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-26462814
[Presentation] 唾液腺再生モデルにおけるサチライシン様前駆体蛋白質変換酵素PACE4の発現誘導-Part II-2016
- Author(s)
  嶋谷達哉，嶺岸誠，赤松徹也，姚陳娟，長谷川敬展，吉村弘
- Organizer
  第58回歯科基礎医学会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-08-24
- Data Source
  KAKENHI-PROJECT-26462814
[Presentation] 唾液腺の構造と機能2015
- Author(s)
  赤松徹也
- Organizer
  第47回四国歯学会例会
- Place of Presentation
  徳島大学歯学部（徳島県徳島市）
- Year and Date
  2015-06-25
- Invited
- Data Source
  KAKENHI-PROJECT-26462814
[Presentation] Salivary Gland Development, Differentiation, and Regeneration - Role of Subtilisin-like Proprotein Convertase PACE4/SPC42014
- Author(s)
  Tetsuya Akamatsu, Chenjuan Yao, Takahiro Hasegawa, and Hiroshi Yoshimura
- Organizer
  BIT's 1st Annual World Congress of Oral & Dental Medicine
- Place of Presentation
  Haikou (China)
- Year and Date
  2014-11-14
- Invited
- Data Source
  KAKENHI-PROJECT-26462814
[Presentation] 唾液腺再生モデルにおける水チャネルAQP5の発現2014
- Author(s)
  姚陳娟，赤松徹也，長谷川敬展，吉村弘
- Organizer
  第56回歯科基礎医学会学術大会
- Place of Presentation
  福岡国際会議場（福岡県・福岡市）
- Year and Date
  2014-09-27
- Data Source
  KAKENHI-PROJECT-26462814
[Presentation] 唾液腺再生モデルにおけるサチライシン様前駆体蛋白質変換酵素の発現誘導2014
- Author(s)
  嶺岸誠，赤松徹也，姚陳娟，長谷川敬展，吉村弘
- Organizer
  第56回歯科基礎医学会学術大会
- Place of Presentation
  福岡国際会議場（福岡県・福岡市）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-26462814
[Presentation] 唾液腺再生におけるサチライシン様前駆体蛋白質変換酵素PACE4の関与2013
- Author(s)
  赤松徹也,姚陳娟,長谷川敬展,吉村弘
- Organizer
  第55回歯科基礎医学会
- Place of Presentation
  (岡山コンベンションセンター/岡山県)
- Data Source
  KAKENHI-PROJECT-23592737
[Presentation] 唾液腺再生におけるサチライシン様前駆体蛋白質変換酵素PACE4の関与2013
- Author(s)
  赤松徹也，姚陳娟，長谷川敬展，吉村弘
- Organizer
  第55回歯科基礎医学会
- Place of Presentation
  岡山コンベンションセンター（岡山県）
- Data Source
  KAKENHI-PROJECT-23592737
[Presentation] Prenatal Expression of Rat Salivary AQP5 is Dependent on the Submandibular Gland Development Mediated by a Subtilisin-like Proprotein Convertase PACE42007
- Author(s)
  Tetsuya Akamatsu
- Organizer
  The 5th International Conference of Aquaporin
- Place of Presentation
  Nara, Japan
- Data Source
  KAKENHI-PROJECT-18390493
[Presentation] 唾液腺腺房細胞の分化とAQP5発現2007
- Author(s)
  赤松徹也
- Organizer
  第49回歯科基礎医学会学術大会並びに総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-18390493
[Presentation] Prenatal Expression of Rat Salivary AQP5 is Dependent on the Submandibular Gland Development Mediated by a Subtilisin-like Proprotein Convertase PACE42007
- Author(s)
  Tetsuya Akamatsu
- Organizer
  The 5th International Conference of Aquaporin
- Place of Presentation
  Nara,Japan
- Year and Date
  2007-07-14
- Data Source
  KAKENHI-PROJECT-18390493
[Presentation] Prenatal expression of rat salivary AQP5 is dependent on the submandibular gland development mediated by a subtilisin-like proprotein convertase PACE42007
- Author(s)
  Akamatsu, T.
- Organizer
  5th International Conference of Aquaporin
- Place of Presentation
  Nara
- Year and Date
  2007-07-14
- Data Source
  KAKENHI-PROJECT-18791369
[Presentation] 唾液腺腺房細胞の発生・分化・成熟化と水チャネルAQP5発現2007
- Author(s)
  赤松徹也
- Organizer
  第59回日本生理学会中四国地方会
- Place of Presentation
  徳島
- Year and Date
  2007-11-10
- Data Source
  KAKENHI-PROJECT-18791369
[Presentation] Differentiation of salivary acinar cells and AQP5 expression2007
- Author(s)
  赤松徹也
- Organizer
  第49回歯科基礎医学会
- Place of Presentation
  札幌
- Year and Date
  2007-08-31
- Data Source
  KAKENHI-PROJECT-18791369
[Presentation] 唾液腺腺房細胞の分化とAQP5発現2007
- Author(s)
  赤松徹也
- Organizer
  第49回歯科基礎医学会学術大会並びに総会
- Place of Presentation
  札幌
- Year and Date
  2007-08-31
- Data Source
  KAKENHI-PROJECT-18390493

1. HOSOI Kazuo (10049413)

# of Collaborated Projects : 8results

# of Collaborated Products : 10results
2. KANAMORI Norio (90064865)

# of Collaborated Projects : 5results

# of Collaborated Products : 3results
3. YAO Chenjuan (20432750)

# of Collaborated Projects : 3results

# of Collaborated Products : 19results
4. HASEGAWA Takahiro (50447273)

# of Collaborated Projects : 3results

# of Collaborated Products : 7results
5. TADA Jun (00314865)

# of Collaborated Projects : 3results

# of Collaborated Products : 0results
6. TSUMURA Keiko (50127841)

# of Collaborated Projects : 2results

# of Collaborated Products : 0results
7. MATSUMOTO Takuya (90284299)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. KIKKAWA Yamato (20274227)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
9. MATSUURA Sachiko (50139854)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
10. HANEJI Tatsuji (50156379)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
11. NAKAJO Nobuyoshi (80069046)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
12. YOSHIMOTO Katsuhiko (90201863)

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13. MIZUSAWA Noriko (80254746)

# of Collaborated Projects : 1results

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14. 吉村弘 (90288845)

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15. 飯田博一 (10335797)

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16. 谷村明彦 (70217149)

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17. 石井久淑 (00275489)

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18. 根津顕弘 (00305913)

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19. 森田貴雄 (20326549)

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20. 李雪飛

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21. NUNUK Purwanti

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22. MILEVA Ratko Karabasil

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23. AZLINA Ahmad

# of Collaborated Projects : 1results

# of Collaborated Products : 3results
24. JAVKHLAN Purevjav

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AKAMATSU Tetsuya 赤松 徹也

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唾液腺Ca2+応答の低侵襲的長期間イメージング技術の確立と機能・再生研究Ongoing

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Elucidation of Molecular Mechanism of the Salivary Gland Regeneration ~ Toward the application to the Regenerative Medicine for Xerostomia ~Principal Investigator

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Elucidation of the molecular mechanism on the differentiation/maturation and functional expression of salivary acinar cell toward conquest of xerostomia.Principal Investigator

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唾液腺腺房細胞の分化誘導、及び機能発現の分子メカニズムの解明Principal Investigator

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水チャネル,アクアポリンの唾液腺発生過程における発現・局在及び機能制御機構の解明Principal Investigator

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歯・唾液腺発生過程でのプロセシング酵素PACE4の発現制御機構及び生理機能の解明Principal Investigator

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口腔組織(歯,舌,唾液腺)発生におけるサチライシン様プロ蛋白質変換酵素の役割Principal Investigator

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AKAMATSU Tetsuya 赤松徹也

[Book] 口腔生物学-各論唾液腺(天野修、草間薫編集)2006