Yoshimoto Takanobu 吉本貴宣

… Alternative Names

YOSHIMOTO Takanobu 吉本貴宣

吉本貴宣ヨシモトタカノブ

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Researcher Number	80297457
Other IDs
Affiliation (Current)	2025: 東京科学大学, その他の部局等, 非常勤講師
Affiliation (based on the past Project Information) *help	2019 – 2021: 東京医科歯科大学, 医学部, 非常勤講師 2016 – 2018: 東京医科歯科大学, 医学部附属病院, 講師 2012 – 2014: 東京医科歯科大学, 医学部附属病院, 講師 2010: 東京医科歯科大学, 医学部・附属病院, 助教 2007 – 2010: Tokyo Medical and Dental University, Department of Clinical and Molecular Endocrinology, assistant professor … More 2004 – 2006: 東京医科歯科大学, 医学部附属病院, 助手 2005: 東京医科歯科大学, 医学附属病院, 助手 1999: 東京女子医大, 医学部, 助手 1998: 東京女子医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Basic Section 52010:General internal medicine-related / Laboratory medicine / Endocrinology Except Principal Investigator Circulatory organs internal medicine / Kidney internal medicine
Keywords	Principal Investigator アルドステロン / 副腎腫瘍 / 血管病態学 / ミネラロコルチコイド受容体 / 受容体 / miRNA / マイクロRNA / renin-angiotensin system / oxidative stress / receptor … More / mineralocorticoid receptor / aldosterone / レニン・アンジオテンシン系 / 酸化ストレス / 分子血管病態学 / β遮断薬 / 高血圧 / ナトリウム利尿ペプチド … More Except Principal Investigator 生理活性物質 / 情報伝達 / 受容体 / 発現調節 / サルーシン / 遺伝子導入 / siRNA / ウロテンシンII Less

significance of micro RNA as biomarker in primary aldosteronismPrincipal Investigator
- Principal Investigator
  
  Yoshimoto Takanobu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Tokyo Medical and Dental University
Genomics in primary aldosteronismPrincipal Investigator
- Principal Investigator
  
  Yoshimoto Takanobu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tokyo Medical and Dental University
Pathophysiology of aldosterone inducible genesPrincipal Investigator
- Principal Investigator
  
  YOSHIMOTO Takanobu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokyo Medical and Dental University
Comprehensive analysis of aldosterone-regulated genes in human vascular cellsPrincipal Investigator
- Principal Investigator
  
  YOSHIMOTO Takanobu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokyo Medical and Dental University
Mechanism of aldosterone-induced vascular injury: role of angiotensin II and other factorsPrincipal Investigator
- Principal Investigator
  
  YOSHIMOTO Takanobu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokyo Medical and Dental University
新規降圧ペプチド(salusin)の発現調節と心臓での受容体・情報伝達系の解明
- Principal Investigator
  
  平田結喜緒
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokyo Medical and Dental University
腎内ウロテンシンIIのsiRNAを用いた遺伝子発現制御による病態生理学的意義の解明
- Principal Investigator
  
  平田結喜緒
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokyo Medical and Dental University
ナトリウム利尿ペプチド受容体サブタイプの病態生理学的意義Principal Investigator
- Principal Investigator
  
  吉本貴宣
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Endocrinology
- Research Institution
  Tokyo Women's Medical University

[Book] アルドステロンの心血管作用2010
- Author(s)
  吉本貴宣、平田結喜緒
- Publisher
  診断と治療社(東京)
- Data Source
  KAKENHI-PROJECT-20590879
[Book] アルドステロン2010
- Author(s)
  吉本貴宣、平田結喜緒
- Publisher
  診断と治療社(東京)
- Data Source
  KAKENHI-PROJECT-20590879
[Book] 原発性アルドステロン症との合併例2009
- Author(s)
  吉本貴宣、泉山肇、平田結喜緒
- Publisher
  診断と治療社(東京)
- Data Source
  KAKENHI-PROJECT-20590879
[Book] 腎血管性高血圧2009
- Author(s)
  吉本貴宣、平田結喜緒
- Publisher
  診断と治療社(東京)
- Data Source
  KAKENHI-PROJECT-20590879
[Book] 心血管リスクホルモンとしてのアルドステロンおよび受容体の機能と役割をみる2009
- Author(s)
  吉本貴宣、平田結喜緒
- Publisher
  先端医学社(東京)
- Data Source
  KAKENHI-PROJECT-20590879
[Book] 原発性アアルドステロン症診療マニュアル2007
- Author(s)
  吉本貴宣
- Total Pages
  2
- Publisher
  診断と治療社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Book] 「アルドステロンの心血管作用」原発性アルドステロン症診療マニュアル2007
- Author(s)
  吉本貴宣、平田結喜緒
- Total Pages
  2
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-18590804
[Book] Adrenomedullin receptor and signal transduction. In Adrenomedullin in Cardiovascular Disease2005
- Author(s)
  Yoshimoto T, Hirata Y
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-17390228
[Journal Article] Diverse pathological lesions of primary aldosteronism and their clinical significance2021
- Author(s)
  Nishimoto Koshiro、JRAS Study Group、Umakoshi Hironobu、Seki Tsugio、Yasuda Masanori、Araki Ryuichiro、Otsuki Michio、Katabami Takuyuki、Shibata Hirotaka、Ogawa Yoshihiro、Wada Norio、Sone Masakatsu、Okamura Shintaro、Izawa Shoichiro、Miyauchi Shozo、Yoshimoto Takanobu、Tsuiki Mika、Naruse Mitsuhide
- Journal Title
  
  Hypertension Research
  
  Volume: 44 Issue: 5 Pages: 498-507
- DOI
  10.1038/s41440-020-00579-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09205, KAKENHI-PROJECT-18K08214, KAKENHI-PROJECT-19K07885, KAKENHI-PROJECT-20K17493
[Journal Article] Diabetes Mellitus Itself Increases Cardio-Cerebrovascular Risk and Renal Complications in Primary Aldosteronism2020
- Author(s)
  Saiki A、Otsuki M、Tamada D、Kitamura T、Shimomura I、Kurihara I、Ichijo T、Takeda Y、Katabami T、Tsuiki M、Wada N、Yanase T、Ogawa Y、Kawashima J、Sone M、Inagaki N、Yoshimoto T、Okamoto R、Takahashi K、Kobayashi H、Tamura K、Kamemura K、Yamamoto K、Izawa S、Kakutani M、Yamada M、Tanabe A、Naruse M
- Journal Title
  
  The Journal of Clinical Endocrinology & Metabolism
  
  Volume: 105 Issue: 7 Pages: e2531-e2537
- DOI
  10.1210/clinem/dgaa177
- NAID
  120006953396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07885
[Journal Article] Obesity predicts persistence of resistant hypertension after surgery in patients with primary aldosteronism2020
- Author(s)
  Nakamaru R、Yamamoto K、Rakugi H、Akasaka H、Kurihara I、Ichijo T、Takeda Y、Katabami T、Tsuiki M、Wada N、Ogawa Y、Kawashima J、Sone M、Yoshimoto T、Okamoto R、Fujita M、Kobayashi H、Tamura K、Kamemura K、Okamura S、Kakutani M、Tanabe A、Naruse M、JPAS/JRAS Study Group
- Journal Title
  
  Clinical Endocrinology
  
  Volume: 93 Issue: 3 Pages: 229-237
- DOI
  10.1111/cen.14203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07885
[Journal Article] Nadir Aldosterone Levels After Confirmatory Tests Are Correlated With Left Ventricular Hypertrophy in Primary Aldosteronism.2020
- Author(s)
  Ohno Y, Sone M, Inagaki N, Kawashima A, Takeda Y, Yoneda T, Kurihara I, Itoh H, Tsuiki M, Ichijo T, Katabami T, Wada N, Sakamoto R, Ogawa Y, Yoshimoto T, Yamada T, Kawashima J, Matsuda Y, Kobayashi H, Kamemura K, Yamamoto K, Otsuki M, Okamura S, Izawa S, Okamoto R, Tamura K, Tanabe A, Naruse M; JPAS/JRAS Study Group*.
- Journal Title
  
  Hypertension.
  
  Volume: - Issue: 6 Pages: 1475-1482
- DOI
  10.1161/hypertensionaha.119.14601
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09880, KAKENHI-PROJECT-19K07885, KAKENHI-PROJECT-18H02859
[Journal Article] miRNA299 involvement in CYP11B2 expression in aldosterone-producing adenoma2019
- Author(s)
  Nakano Yujiro、Yoshimoto Takanobu、Watanabe Ryo、Murakami Masanori、Fukuda Tatsuya、Saito Kazutaka、Fujii Yasuhisa、Akashi Takumi、Tanaka Toshihiro、Yamada Tetsuya、Naruse Mitsuhide、Ogawa Yoshihiro
- Journal Title
  
  European Journal of Endocrinology
  
  Volume: 181 Issue: 1 Pages: 69-78
- DOI
  10.1530/eje-18-0882
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07885, KAKENHI-PROJECT-18H02859
[Journal Article] Effect of Eplerenone on the Glomerular Filtration Rate (GFR) in Primary Aldosteronism: Sequential Changes in the GFR During Preoperative Eplerenone Treatment to Subsequent Adrenalectomy2018
- Author(s)
  Nakano Yujiro、Yoshimoto Takanobu、Fukuda Tatsuya、Murakami Masanori、Bouchi Ryotaro、Minami Isao、Hashimoto Koshi、Fujii Yasuhisa、Kihara Kazunori、Ogawa Yoshihiro
- Journal Title
  
  Intern. Med.
  
  Volume: 57 Issue: 17 Pages: 2459-2466
- DOI
  10.2169/internalmedicine.0438-17
- NAID
  130007480026
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2018-09-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08962
[Journal Article] Molecular characteristics of the KCNJ5 mutated aldosterone-producing adenomas2017
- Author(s)
  Murakami Masanori、Yoshimoto Takanobu、Nakabayashi Kazuhiko、Nakano Yujiro、Fukaishi Takahiro、Tsuchiya Kyoichiro、Minami Isao、Bouchi Ryotaro、Okamura Kohji、Fujii Yasuhisa、Hashimoto Koshi、Hata Ken-ichiro、Kihara Kazunori、Ogawa Yoshihiro
- Journal Title
  
  Endocrine-Related Cancer
  
  Volume: 24 Issue: 10 Pages: 531-541
- DOI
  10.1530/erc-17-0117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07137, KAKENHI-PROJECT-16K08962
[Journal Article] Expression of inflammation-related genes in aldosterone-producing adenomas with KCNJ5 mutation.2016
- Author(s)
  Murakami M, Yoshimoto T, Nakano Y, Tsuchiya K, Minami I, Bouchi R, Fujii Y, Nakabayashi K, Hashimoto K, Hata K, Kihara K, Ogawa Y.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 476 Issue: 4 Pages: 614-619
- DOI
  10.1016/j.bbrc.2016.06.007
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K19392, KAKENHI-PROJECT-16K08962
[Journal Article] 最新臨床高血圧学-高血圧治療の最前線- ライフステージ・タイプ別の高血圧の治療・管理二次性高血圧内分泌性高血圧クッシング症候群2014
- Author(s)
  吉本貴宣、南勲、小川佳宏
- Journal Title
  
  日本臨床
  
  Volume: ７２ Pages: 518-521
- Data Source
  KAKENHI-PROJECT-24591110
[Journal Article] 高血圧をめぐる最新の話題脂肪細胞2014
- Author(s)
  吉本貴宣、小川佳宏
- Journal Title
  
  最新医学
  
  Volume: 69 Pages: 125-132
- Data Source
  KAKENHI-PROJECT-24591110
[Journal Article] Impact of increased visceral　adiposity with normal weight on the progression of arterial stiffness in Japanese　patients with type 2 diabetes.2014
- Author(s)
  Bouchi R, Minami I, Ohara N, Nakano Y, Nishitani R, Murakami M, Takeuchi T,　Akihisa M, Fukuda T, Fujita M, Yoshimoto T, Ogawa Y
- Journal Title
  
  BMJ Open Diabetes Res Care.
  
  Volume: 3 Issue: 1 Pages: e000081-e000081
- DOI
  10.1136/bmjdrc-2015-000081
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591110
[Journal Article] Hydrogen sulfide increases nitric oxideproduction with calcium-dependent activation of endothelial nitric oxide synthase in endothelial cells2013
- Author(s)
  Kida M, Sugiyama T, Yoshimoto T, Ogawa Y
- Journal Title
  
  European Journal of Pharmacological Science
  
  Volume: 48 Issue: 1-2 Pages: 211-215
- DOI
  10.1016/j.ejps.2012.11.001
- Data Source
  KAKENHI-PROJECT-24591110
[Journal Article] 副腎CTスキャンの意義と限界2013
- Author(s)
  吉本貴宣、小川佳宏
- Journal Title
  
  カレントセラピー
  
  Volume: 31 Pages: 689-693
- Data Source
  KAKENHI-PROJECT-24591110
[Journal Article] アルドステロンと病態：アルドステロンによる動脈硬化・血管障害2013
- Author(s)
  吉本貴宣、小川佳宏
- Journal Title
  
  The Lipid
  
  Volume: 24 Pages: 239-244
- Data Source
  KAKENHI-PROJECT-24591110
[Journal Article] 脂肪組織からアディポサイトカインを介した代謝情報ネットワークと高血圧2012
- Author(s)
  吉本貴宣、小川佳宏
- Journal Title
  
  血管医学
  
  Volume: 13 Pages: 27-33
- Data Source
  KAKENHI-PROJECT-24591110
[Journal Article] Transcriptome analysis of aldosterone-regulated genes in human vascular endothelial cell lines stably expressing mineralocorticoid receptor2011
- Author(s)
  Sekizawa N, Yoshimoto T, Hayakawa E, Suzuki N, Sugiyama T, Hirata Y.
- Journal Title
  
  Mol Cell Endocrinol
  
  Volume: 341 Pages: 78-88
- Data Source
  KAKENHI-PROJECT-20590879
[Journal Article] Endothelial dysfunction aassociated with hypercortisolism is reversible in Cushing's syndrome2010
- Author(s)
  Akaza I, Yoshimoto T, Tsuchiya K, HirataY
- Journal Title
  
  Encocr J
  
  Volume: 57 Pages: 245-252
- Data Source
  KAKENHI-PROJECT-20590879
[Journal Article] Improvement of endothelial function in patients with hypertension and type 2 diabetes after treatment with telmisartan2010
- Author(s)
  Wago T, Yoshimoto T, Akaza I, TsuchiyaK, Izumiyama H, Doi M, Hirata Y
- Journal Title
  
  Hypertens Res
  
  Volume: 33 Pages: 796-801
- NAID
  10027681549
- Data Source
  KAKENHI-PROJECT-20590879
[Journal Article] Endothelial dysfunction aassociated with hypercortisolism is reversible in Cushing's syndrome.2010
- Author(s)
  Akaza I, Yoshimoto T
- Journal Title
  
  Endocr J
  
  Volume: 57 Pages: 245-252
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590879
[Journal Article] Vasculoprotective effect of cilostazol inaldosterone-induced hypertensive rats2010
- Author(s)
  Sakurada M, Yoshimoto T, Sekizawa N, Hirono Y, Suzuki N, Hirata Y
- Journal Title
  
  Hypertens Res
  
  Volume: 33 Pages: 229-235
- Data Source
  KAKENHI-PROJECT-20590879
[Journal Article] Vasculoprotective effect of cilostazol in aldosterone-induced hypertensive rats2010
- Author(s)
  Sakurada M, Yoshimoto T, et al
- Journal Title
  
  Hypertens Res
  
  Volume: 33 Pages: 229-235
- NAID
  10026127002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590879
[Journal Article] Endothelial dysfunction is related to aldosterone excess and raised blood pressure2009
- Author(s)
  Tsuchiya K, Yoshimoto T, Hirata Y
- Journal Title
  
  Endocr J
  
  Volume: 56 Pages: 553-559
- NAID
  10026914087
- Data Source
  KAKENHI-PROJECT-20590879
[Journal Article] 抗アルドステロン薬2009
- Author(s)
  吉本貴宣、平田結喜緒
- Journal Title
  
  腎と透析 66
  
  Pages: 119-123
- Data Source
  KAKENHI-PROJECT-20590879
[Journal Article] アルドステロンによる血管障害のメカニズム酸化ストレスの視点から2009
- Author(s)
  吉本貴宣、平田結喜緒
- Journal Title
  
  医学のあゆみ 228
  
  Pages: 463-467
- Data Source
  KAKENHI-PROJECT-20590879
[Journal Article] Endothelial dysfunction is related to aldosterone excess and raised blood pressure2009
- Author(s)
  Tsuchiya K, 吉本貴宣, et al.
- Journal Title
  
  Endocr J 56
  
  Pages: 553-559
- NAID
  10026914087
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590879
[Journal Article] Aldosterone induces superoxide generation via Rac1 activation in endothelial cells2008
- Author(s)
  Iwashima F, Yoshimoto T, Minami I, Sakurada M, Hirono Y, Hirata Y
- Journal Title
  
  Endocrinology
  
  Volume: 149 Pages: 1009-1014
- Data Source
  KAKENHI-PROJECT-20590879
[Journal Article] Aldosterone induces superoxide generation via Rac1 activation inendothelial cells2008
- Author(s)
  Minami I, Yoshimoto T, et al.
- Journal Title
  
  Endocr J 55
  
  Pages: 839-846
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590879
[Journal Article] Aldosterone induces superoxide generation via Rac1 activation in endothelial cells.2008
- Author(s)
  Iwashima F, Yoshimoto T, Minami I, et. al.
- Journal Title
  
  Endocrinology 149
  
  Pages: 1009-1014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] Aldosterone induces superoxide generation via Rac1 activation in endothelial cells2008
- Author(s)
  Iwashima F, Yoshimoto T, et al.
- Journal Title
  
  Endocrinology 149
  
  Pages: 1009-1014
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] Aldosterone induces superoxide generation via Rac1 activation inendothelial cells2008
- Author(s)
  Iwashima F, Yoshimoto T, et al
- Journal Title
  
  Endocrinology 149
  
  Pages: 1009-1014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590879
[Journal Article] Aldosterone induces superoxide generation via Racl activation in endothelial cells.2008
- Author(s)
  Iwashima F, Yoshimoto T, et al.
- Journal Title
  
  Endocrinology 149
  
  Pages: 1009-1014
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] Diagnostic accuracy of adrenal venous sampling in comparison with other parameters in primary aldosteronism2008
- Author(s)
  Minami I, Yoshimoto T, Hirono Y, Izumiyama H, Doi M, Hirata Y
- Journal Title
  
  Endocr J
  
  Volume: 55 Pages: 839-846
- NAID
  10024422812
- Data Source
  KAKENHI-PROJECT-20590879
[Journal Article] アルドステロンの分泌調節機序2008
- Author(s)
  吉本貴宣, 平田結喜緒
- Journal Title
  
  Mebio 25
  
  Pages: 6-13
- Data Source
  KAKENHI-PROJECT-20590879
[Journal Article] Angiotensin II receptor type 1- mediated vascular oxidative stress and proinflammatory gene expression in aldosterone-induced hypertension: the possible role of local renin-angiotensin system.2007
- Author(s)
  Hirono Y, Yoshimoto T, et al.
- Journal Title
  
  Endocrinology 148
  
  Pages: 1688-1696
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] Caridiovascular function of aldosterone2007
- Author(s)
  Yoshimoto T
- Journal Title
  
  Genpatsusei Aldosterone-shou Shinryou Manual (Shindan-To-Chiryou Sha) Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] 血管内皮障害とアルドステロン2007
- Author(s)
  吉本貴宣, 他
- Journal Title
  
  医学のあゆみ 221
  
  Pages: 739-742
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] Angiotensin II receptor type 1- mediated vascular oxidative stress and proinflammatory gene expression in aldosterone-induced hypertension : the possible role of local renin-angiotensin system2007
- Author(s)
  Hirono Y, Yoshimoto T, et al.
- Journal Title
  
  Endocrinology 148
  
  Pages: 1688-1696
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] Angiotensin II receptor type 1-mediated vascular oxidative stress and proinflammatory gene expression in aldosterone-induced hypertension : the possible role of local renin-angiotensin system.2007
- Author(s)
  Hirono Y, Yoshimoto T, Suzuki N et al.
- Journal Title
  
  Endocrinology 148.4
  
  Pages: 1688-1696
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] Aldosterone as a cardiovascular risk hormone2007
- Author(s)
  Yoshimoto T, Hirata Y
- Journal Title
  
  Endocrine J 54
  
  Pages: 359-370
- NAID
  130004770030
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] Endothelial injury and aldosterone.2007
- Author(s)
  Yoshimoto T, Hirata Y.
- Journal Title
  
  Igaku no Ayumi 221
  
  Pages: 739-742
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] Aldosterone as a cardiovascular risk hormone.2007
- Author(s)
  Yoshimoto T, Hirata Y.
- Journal Title
  
  Endocrine J 54
  
  Pages: 359-370
- NAID
  130004770030
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] 心血管障害におけるアルドステロンの病態生理学的意義2006
- Author(s)
  吉本貴宣, 他
- Journal Title
  
  血管 29
  
  Pages: 47-55
- NAID
  10017990347
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] アルドステロンによる血管作用2006
- Author(s)
  吉本貴宣, 他
- Journal Title
  
  血圧 13
  
  Pages: 721-725
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] A Case of acromegaly associated with subclinical Cushing's disease2006
- Author(s)
  Tsuchiya K, Ohta K, Yoshimoto T, et al.
- Journal Title
  
  Endocrine J 53.5
  
  Pages: 679-685
- NAID
  10020613336
- Data Source
  KAKENHI-PROJECT-17390228
[Journal Article] Vascular effect by aldosterone2006
- Author(s)
  Yoshimoto T, Hirata Y.
- Journal Title
  
  Ketsuatsu 13
  
  Pages: 721-725
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] アルドステロン誘導性血管炎の発症機構2006
- Author(s)
  吉本貴宣, 他
- Journal Title
  
  内分泌・糖尿病科 23
  
  Pages: 587-592
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] Pathogenesis of aldosterone-induced vasculitis2006
- Author(s)
  Yoshimoto T, Hirata Y.
- Journal Title
  
  Naibunpitsu Tounyoubyou-Ka 23
  
  Pages: 587-592
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] 心血管リスクホルモンとしてのアルドステロン2006
- Author(s)
  吉本貴宣, 他
- Journal Title
  
  細胞 38
  
  Pages: 16-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] Pathophysiological significance of aldosterone in cardiovascular disease.2006
- Author(s)
  Yoshimoto T, Hirata Y.
- Journal Title
  
  Kekkan 29
  
  Pages: 47-55
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] Aldosterone as a cardiovascular risk hormone2006
- Author(s)
  Yoshimoto T, Hirata Y.
- Journal Title
  
  Saibou 38
  
  Pages: 16-19
- NAID
  130004770030
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] Angiotensin II induces monocyte chemoattractant protein-1 expression via nuclear factor-kappa B-dependent pathway in rat preadipocytes2006
- Author(s)
  Tsuchiya K, Yoshimoto T, Hirono Y, et al.
- Journal Title
  
  Am J Physiol Endocrinol Metab 291.4
- Data Source
  KAKENHI-PROJECT-17390228
[Journal Article] Angiotensin II induces monocyte chemoattractant protein-1 expression via nuclear factor-kappa B-dependent pathway in rat preadipocytes.2006
- Author(s)
  Tsuchiya K, Yoshimoto T, et al.
- Journal Title
  
  Am J Physiol Endocrinol and Metab 291
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] アルドステロン誘導性血管炎の発症機構2006
- Author(s)
  吉本貴宣, 平田結喜緒
- Journal Title
  
  内分泌・糖尿病科 23・6
  
  Pages: 587-592
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] Angiotensin II induces monocyte chemoattractant protein-1 expression via nuclear factor-kappa B-dependent pathway in rat preadipocytes2006
- Author(s)
  Tsuchiya K, Yoshimoto T, et al.
- Journal Title
  
  Am J Physiol Endocrinol Metab 291
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] Subclinical Cushings disease with amelioration of metabolic comorbidities after removal of pituitary tumor2006
- Author(s)
  Minami I, Tateno T, Yoshimoto T, et al.
- Journal Title
  
  Intern Med 45.21
  
  Pages: 1231-1235
- NAID
  130000076614
- Data Source
  KAKENHI-PROJECT-17390228
[Journal Article] Molecular mechanisms of aldosterone-inducecdvas2006
- Author(s)
  Hirono Y, Yoshimoto T, et al.
- Journal Title
  
  Kekkan 29
  
  Pages: 139-144
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Journal Article] A case with type 1 diabetes mellitus and drug-resistant epilepsy : presence of high titer of anti-glutamic acid decarboxylase autoantibodies in serum and cerebrospinal fluid.2005
- Author(s)
  Yoshimoto T et al.
- Journal Title
  
  Intern Med 44・11
  
  Pages: 1174-1177
- Data Source
  KAKENHI-PROJECT-17390228
[Journal Article] Aldosterone increases osteopontin gene expression in rat endothelial cells.2005
- Author(s)
  Sugiyama T, Yoshimoto T, Hirono Y, Sakurada M, Tsuchiya K, Minami I, Iwashima F, Sakai H, Tateno T, Sato R, Hirata Y
- Journal Title
  
  Biochemical Biophysical Research Communication 336.1
  
  Pages: 163-167
- Data Source
  KAKENHI-PROJECT-16659220
[Journal Article] Aldosterone induces angiotensin converting enzyme (ACE) gene expression via JAK2-dependent pathway in rat endothelial cells.2005
- Author(s)
  Sugiyama T, Yoshimoto T, Tsuchiya K, Gochou N, Hirono Y, Tateno T, Fukai N, Shichiri M, Hirata Y
- Journal Title
  
  Endocrinology 146・9
  
  Pages: 3900-3906
- Data Source
  KAKENHI-PROJECT-16659220
[Journal Article] Concomitant expression of adrenomedullin and its receptor components in rat adipose tissues.2005
- Author(s)
  Fukai N, Yoshimoto T, Sugiyama T, Ozawa N, Sato R, Shichiri M, Hirata Y
- Journal Title
  
  American Journal of Physiology 288・1
- Data Source
  KAKENHI-PROJECT-16659220
[Journal Article] Adrenomedullin inhibits angiotensin II-induced oxidative stress and gene expression in rat endothelial cells.2005
- Author(s)
  Yoshimoto T et al.
- Journal Title
  
  Hypertens Res 28・2
  
  Pages: 165-172
- NAID
  10016430788
- Data Source
  KAKENHI-PROJECT-17390228
[Journal Article] Adrenomedullin inhibits angiotensin II-induced oxidative stress and gene expression in rat endothelial cells.2005
- Author(s)
  Yoshimoto T, Gochou N, Fukai N, Sugiyama T, Shichiri M, Hirata Y
- Journal Title
  
  Hypertension Research 28・2
  
  Pages: 165-172
- NAID
  10016430788
- Data Source
  KAKENHI-PROJECT-16659220
[Journal Article] Role of urotensin II in peripheral tissue as an autocine/paracrine growth factor2004
- Author(s)
  Yoshimoto T, Matsushita M, Hirata Y
- Journal Title
  
  Peptides 25.10
  
  Pages: 1775-1781
- Data Source
  KAKENHI-PROJECT-16659220
[Presentation] アルドステロン産生腺腫（APA）のゲノム・エピゲノム解析2018
- Author(s)
  吉本貴宣
- Organizer
  第９１回日本内分泌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08962
[Presentation] アルドステロン産生腺腫（APA）のゲノミクス2017
- Author(s)
  吉本貴宣
- Organizer
  心血管代謝週間CVMW2017
- Data Source
  KAKENHI-PROJECT-16K08962
[Presentation] ゲノム・エピゲノム解析からみた原発性アルドステロン症（APA)の多様性2017
- Author(s)
  吉本貴宣、村上正憲、中野雄二郎、小川佳宏
- Organizer
  第90回日本内分泌学会学術総会
- Place of Presentation
  京都市勧業館みやこめっせ
- Year and Date
  2017-04-20
- Data Source
  KAKENHI-PROJECT-16K08962
[Presentation] アルドステロン産生副腎腫瘍のゲノムワイドDNAメチル化解析2014
- Author(s)
  村上正憲、吉本貴宣　他
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡市　福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24591110
[Presentation] 血管内皮細胞における硫化水素の血管新生促進作用2012
- Author(s)
  杉山徹、木田道也、吉本貴宣、小川佳宏
- Organizer
  第16回日本心血管内分泌代謝学会学術総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591110
[Presentation] 原発性アルドステロン症に対する手術・薬物治療による高血圧・心腎機能への効果2012
- Author(s)
  大橋琢也、吉本貴宣、山口実菜、三原正朋、杉山徹、泉山肇、平田結喜緒、内村功、小川佳宏
- Organizer
  第85回日本内分泌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24591110
[Presentation] Distinct Uptake of 18F-Fluorodeoxyglucose by Brown Adipose Tissue in Catecholamine-Secreting Tumor2010
- Author(s)
  Sekizawa N, Izumiyama H, Yoshimoto T, Hirata Y
- Organizer
  14th International Congress of Endocrinology
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-20590879
[Presentation] ミネラロコルチコイド受容体(MR)導入血管内皮細胞におけるアルドステロンによるANGPTL4の発現制御機構2010
- Author(s)
  関澤直子、吉本貴宣、Jack Beadle、早川惠理、杉山徹、平田結喜緒
- Organizer
  第33回日本高血圧学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20590879
[Presentation] アルドステロン高血圧モデルでの心血管障害発症の分子機構-酸化ストレスと炎症の意義2009
- Author(s)
  吉本貴宣、平田結喜緒
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590879
[Presentation] Molecular mechan isms of aldosterone-induced caridovascular injury2009
- Author(s)
  吉本貴宣, 他
- Organizer
  第82回日本薬理学会年会(シンポジウム)
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590879
[Presentation] ヒト血管内皮細胞へのミネラロコルチコイド受容体(MR)遺伝子導入細胞株の樹立2009
- Author(s)
  関澤直子、吉本貴宣
- Organizer
  第82回日本内分泌学会学術集会
- Place of Presentation
  前橋
- Data Source
  KAKENHI-PROJECT-20590879
[Presentation] ヒト血管内皮細胞へのミネラロコルチコイド受容体(MR)遺伝子導入細胞株の樹立2009
- Author(s)
  関澤直子、吉本貴宣、早川惠理、土屋恭一郎、七里眞義、平田結喜緒
- Organizer
  第82回日本内分泌学会学術総会
- Place of Presentation
  前橋市
- Data Source
  KAKENHI-PROJECT-20590879
[Presentation] 血管内皮細胞でのアルドステロン作用の解明を目指したミネラロコルチコイド受容体(MR)遺伝子過剰発現内皮細胞株の樹立2009
- Author(s)
  関澤直子、吉本貴宣、早川惠理、杉山徹、七里眞義、平田結喜緒
- Organizer
  第13回日本心血管内分泌代謝学会学術総会
- Place of Presentation
  さいたま市
- Data Source
  KAKENHI-PROJECT-20590879
[Presentation] アルドステロンによるミネラロコルチコイド受容体(MR)を介した血管障害のメカニズム2007
- Author(s)
  吉本貴宣、平田結喜緒
- Organizer
  第11回日本心血管内分泌代謝学会学術総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-18590804
[Presentation] Mechanisms of aldosterone-induced vascular injury through mineralocorticoid receptor.2007
- Author(s)
  Yoshimoto T, et al.
- Organizer
  10^<th> Nihon Shin-kekkann Naibunpitsu Taisha Gakkai Symposium
- Place of Presentation
  Tokyo
- Year and Date
  2007-11-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Presentation] アルドステロンによるミネラロコルチコイド受容体(MR)を介した血管障害のメカニズム2007
- Author(s)
  吉本貴宣, 他
- Organizer
  第11回日本心血管内分泌代謝学会学術総会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2007-11-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Presentation] 血管内皮細胞を主座としたアルドステロン誘導性血管炎の分子機構2006
- Author(s)
  吉本貴宣, 他
- Organizer
  第10回日本心血管内分泌代謝学会シンポジウム
- Place of Presentation
  福井
- Year and Date
  2006-11-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Presentation] Possible involvement of vascular renin-angiotensin system in the development of aldosterone-induced vascular injury in rats2006
- Author(s)
  Yoshimoto T, et al.
- Organizer
  The 21st Scientific Meeting of the international Society of Hypertension Investigator-Initiated Symposia
- Place of Presentation
  Takarazuka
- Year and Date
  2006-10-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Presentation] Possible involvement of vascular renin-angiotensin system in the development of aldosterone-induced vascular injury in rats2006
- Author(s)
  Yoshimoto T, et al.
- Organizer
  The 21st Scientific Meeting of the International Society of Hypertension Investigator-Initiated Symposia: Chymase Comprehending Tissue-Angiotensin Generating System
- Place of Presentation
  Takarazuka
- Year and Date
  2006-10-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Presentation] Aldosterone-induced vaculitis based on endothelial injury2006
- Author(s)
  Yoshimoto T, et al.
- Organizer
  10^<th> Nihon Shin-kekkann Naibunpitsu Taisha Gakkai Symposium
- Place of Presentation
  Fukui
- Year and Date
  2006-11-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590804
[Presentation] Integration of Transcriptome and Methylome Analyses to Dissect Molecular Pathogenesis of Primary Aldosteronism
- Author(s)
  Murakami M, Yoshimoto T et al.
- Organizer
  16th International Congress of Endocrinology & the Endocrine Society 96th Annual Meeting & Expo
- Place of Presentation
  Chicago USA
- Year and Date
  2014-06-21 – 2014-06-24
- Data Source
  KAKENHI-PROJECT-24591110

1. 平田結喜緒 (50135787)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. 七里眞義 (10206097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. Hata Kenichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Kihara Kazunori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NISHIMOTO Koshiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. SUGIURA Yuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. SONE Masakatsu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 荒木隆一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 岡村浩司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 村上正憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yoshimoto Takanobu 吉本 貴宣

YOSHIMOTO Takanobu 吉本 貴宣

吉本 貴宣 ヨシモト タカノブ

Research Projects

Research Products

Co-Researchers

significance of micro RNA as biomarker in primary aldosteronismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genomics in primary aldosteronismPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Pathophysiology of aldosterone inducible genesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comprehensive analysis of aldosterone-regulated genes in human vascular cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of aldosterone-induced vascular injury: role of angiotensin II and other factorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規降圧ペプチド(salusin)の発現調節と心臓での受容体・情報伝達系の解明

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

腎内ウロテンシンIIのsiRNAを用いた遺伝子発現制御による病態生理学的意義の解明

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ナトリウム利尿ペプチド受容体サブタイプの病態生理学的意義Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] アルドステロンの心血管作用2010

Author(s)

Publisher

Data Source

[Book] アルドステロン2010

Author(s)

Publisher

Data Source

[Book] 原発性アルドステロン症との合併例2009

Author(s)

Publisher

Data Source

[Book] 腎血管性高血圧2009

Author(s)

Publisher

Data Source

[Book] 心血管リスクホルモンとしてのアルドステロンおよび受容体の機能と役割をみる2009

Author(s)

Publisher

Data Source

[Book] 原発性アアルドステロン症診療マニュアル2007

Author(s)

Total Pages

Publisher

Description

Data Source

Yoshimoto Takanobu 吉本貴宣

YOSHIMOTO Takanobu 吉本貴宣

吉本貴宣ヨシモトタカノブ

[Book] 「アルドステロンの心血管作用」原発性アルドステロン症診療マニュアル2007

[Journal Article] 最新臨床高血圧学-高血圧治療の最前線- ライフステージ・タイプ別の高血圧の治療・管理二次性高血圧内分泌性高血圧クッシング症候群2014

[Journal Article] 高血圧をめぐる最新の話題脂肪細胞2014

[Journal Article] Impact of increased visceral　adiposity with normal weight on the progression of arterial stiffness in Japanese　patients with type 2 diabetes.2014