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Kitazume Shinobu  北爪 しのぶ

… Alternative Names

KAWAGUCHI Shinobu  北爪 しのぶ

SHINOBU Kitazume  北爪 しのぶ

川口 しのぶ  カワグチ シノブ

Less
Researcher Number 80301753
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-4757-723X
External Links
Affiliation (Current) 2025: 福島県立医科大学, 保健科学部, 教授
Affiliation (based on the past Project Information) *help 2021 – 2024: 福島県立医科大学, 保健科学部, 教授
2018: 国立研究開発法人理化学研究所, 脳神経科学研究センター, 客員研究員
2015 – 2017: 国立研究開発法人理化学研究所, 疾患糖鎖研究チーム, 副チームリーダー
2013 – 2014: 独立行政法人理化学研究所, 疾患糖鎖研究チーム, 副チームリーダー
2009 – 2011: The Institute of Physical and Chemical Research, 疾患糖鎖研究チーム, 副チームリーダー … More
2007: The Institute of Physical and Chemical Research, Disease Glycomics, Deputy Laboratory Head
2004 – 2006: 独立行政法人理化学研究所, 糖鎖機能研究チーム, 研究員
2003: 独立行政法人理化学研究所, 糖鎖機能研究チーム, フロンティア研究員
2002: 理化学研究所, 糖鎖機能研究チーム, フィロンティア研究員
2001 – 2002: 理化学研究所, 糖鎖機能研究チーム, フロンティア研究員
2000: 理化学研究所, 糖鎖機能研究チーム, 基礎科学特別研究員
1999: 理化学研究所, 糖遺伝情報研究チーム, 基礎科学特別研究員
1999: 理化学研究所, 糖遺伝情報研究チーム, 研究員 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Functional biochemistry / Basic Section 52010:General internal medicine-related / General medical chemistry / Biological Sciences / Tumor biology / Functional biochemistry / Structural biochemistry
Except Principal Investigator
Biological Sciences / Basic Section 56010:Neurosurgery-related / Basic Section 52020:Neurology-related / General medical chemistry / Functional biochemistry
Keywords
Principal Investigator
ST6Gal I / シアル酸転移酵素 / BACE1 / 分泌 / 血管内皮細胞 / アポトーシス / LEC / 血管新生 / α2,6-シアル酸 / シアル酸 … More / PECAM / 肝炎 / アミノペプチダーゼ / バイオマーカー / 腫瘍血管新生 / 血漿 / 酸化ストレス / サンドイッチELISA / ノックアウトマウス / MALDI-TOFMS / セクレターゼ / 抗Aβ抗体 / アミロイドβ前駆体タンパク質 / ARIA / 認知症 / 血小板 / 血液凝固 / アミロイドβ / アルツハイマー病 / Aβ / APP / アンタゴニスト / 血管内内皮細胞 / 化合物アレイ / VEGFR2 / 糖鎖 / VEGFR2 / インテグリン / apoptosis / sialyltransferase / endothelial cell / オリゴデンロサイト / アストロサイト / O-マンノース糖鎖 / キュプリゾン / 活性化アストロサイト / 再ミエリン化 / 脱髄 / Oーマンノース糖鎖 / VEGF / 腫瘍内血管新生 / PECAM / レクチン / 細胞接着 / ITIM / 接着分子 / SHP2 / SNA / PST / エキソペプチダーゼ / St6Gal l / アルツハイマー / エキソピプチダーゼ / ST6Gall / ST8SiaIV / ST8SiaII / ST6GalI / ポリシアル酸 / ゴルジ装置 … More
Except Principal Investigator
アルツハイマー病 / βセクレターゼ / 糖鎖 / シアル酸転移酵素 / アミノペプチダーゼ / 神経線維腫症2型 / PTPRZ / 補体 / アミロイドβ / アミロイド関連画像異常 / 脳アミロイド血管症 / GnT-III / バイセクト糖鎖 / BACE1 / α2,6シアル酸化 / アミロイド前駆体タンパク質(APP) / α2,6シアル酸転移酵素 / βセクレターゼ(BACE1) / バイオマーカー / 切断産物 / βセレクターゼノックアウトマウス / 脳脊髄液 / 糖転移酵素 / α2,6シアル酸伝移酵素 / ディファレンシャル・ディスプレイ / 細胞分化 / Neuro2a細胞 / P19細胞 / GDAP Less
  • Research Projects

    (22 results)
  • Research Products

    (132 results)
  • Co-Researchers

    (25 People)
  •  Elucidation of the Molecular mechanism and development of predictive markers for ARIA using animal modelsPrincipal Investigator

    • Principal Investigator
      北爪 しのぶ
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Fukushima Medical University
  •  Overcoming amyloid-related imaging abnormalities associated with anti-amyloid-beta monoclonal antibodies

    • Principal Investigator
      新堂 晃大
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Mie University
  •  Development of a new glycoprotein-targeted therapy for neurofibromatosis type 2

    • Principal Investigator
      藤井 正純
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Fukushima Medical University
  •  Multifaceted functional analysis of endothelial amyloid precursor protein metabolites and their application to clinical markersPrincipal Investigator

    • Principal Investigator
      北爪 しのぶ
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Fukushima Medical University
  •  Screening of PECAM antagonist having anti-tumor angiogenesisPrincipal Investigator

    • Principal Investigator
      Kitazume Shinobu
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Institute of Physical and Chemical Research
  •  脳特異的な分岐型Oマンノース糖鎖がグリアアセンブリに果たす役割Principal Investigator

    • Principal Investigator
      北爪 しのぶ
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Institute of Physical and Chemical Research
  •  A novel trafficking mechanism regulated by bisecting GlcNAc, an Alzheimer's disease accelerator

    • Principal Investigator
      Kizuka Yasuhiko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General medical chemistry
    • Research Institution
      Institute of Physical and Chemical Research
  •  A role of sialic acid for tumor angiogenesisPrincipal Investigator

    • Principal Investigator
      Kitazume Shinobu
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor biology
    • Research Institution
      Institute of Physical and Chemical Research
  •  Role of Sialic Acid for AngiogenesisPrincipal Investigator

    • Principal Investigator
      KAWAGUCHI Shinobu
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Effect of sialylation on leukocyte transmigration through endothelial cellsPrincipal Investigator

    • Principal Investigator
      SHINOBU Kitazume
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      The Institute of Physical and Chemical Research
  •  生体内における糖鎖修飾を介したAPP代謝の調節

    • Principal Investigator
      橋本 康弘
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  酸化ストレスなどの病態シグナルにおける糖鎖変化とその生理的意義の解明Principal Investigator

    • Principal Investigator
      北爪 しのぶ
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  新規バイオマーカーを利用したアルツハイマー病の診断

    • Principal Investigator
      橋本 康弘
    • Project Period (FY)
      2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  アルツハイマー病態における糖鎖変化の網羅的解析

    • Principal Investigator
      橋本 康弘
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  癌特異的な分泌型シアル酸転移酵素を癌早期診断薬に用いるための基礎研究Principal Investigator

    • Principal Investigator
      北爪 しのぶ
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  肝炎マーカーとなり得る血清中の可溶型シアル酸転移酵素Principal Investigator

    • Principal Investigator
      北爪 しのぶ
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  糖転移酵素分泌を制御するBACE1プロテアテーゼとアミノペプチダーゼPrincipal Investigator

    • Principal Investigator
      北爪 しのぶ
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      The Institute of Physical and Chemical Research
  •  新規BACE基質の網羅的な検索とその切断のアルツハイマー病態における意義

    • Principal Investigator
      橋本 康弘
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  癌特異的な分泌型シアル酸転移酵素を癌スクリーニングに用いるための基礎研究Principal Investigator

    • Principal Investigator
      北爪 しのぶ
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  癌特異的な分泌型シアル酸転移酵素の形成機構Principal Investigator

    • Principal Investigator
      北爪 しのぶ
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      The Institute of Physical and Chemical Research
  •  GDAP-1の機能解析

    • Principal Investigator
      辻 崇一
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      The Institute of Physical and Chemical Research
  •  糖転移酵素のゴルジ装置局在機構Principal Investigator

    • Principal Investigator
      川口 しのぶ
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Structural biochemistry
    • Research Institution
      The Institute of Physical and Chemical Research

All 2022 2018 2017 2016 2015 2014 2013 2011 2010 2009 2007 2006 2005 2004 Other

All Journal Article Presentation Book Patent

  • [Book] 生体の科学2016

    • Author(s)
      北爪しのぶ
    • Total Pages
      11
    • Publisher
      医学書院
    • Data Source
      KAKENHI-PROJECT-16K08601
  • [Book] ST6Gal-I. Handbook of Glycosyltransferases and Related Genes. 2nd Edition.2014

    • Author(s)
      1.S. Kitazume
    • Total Pages
      4
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-25430122
  • [Book] Handbook of Glycosyltransferases and Related Genes. 2nd Edition.2014

    • Author(s)
      S. Kitazume
    • Publisher
      ST6Gal-I.
    • Data Source
      KAKENHI-PUBLICLY-26117522
  • [Book] GnT-IX遺伝子の脳特異的な発現とアイソフォーム「脳21」2011

    • Author(s)
      木塚康彦、兼清健志、北爪しのぶ、谷口直之
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Book] 「脳21」GnT-IX遺伝子の脳特異的な発現とアイソフォーム2011

    • Author(s)
      木塚康彦、兼清健志、北爪しのぶ、谷口直之
    • Total Pages
      85
    • Publisher
      メディカルオンライン
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Book] How does Nand O-glysocylation affect the formation and accumulation of amyloideυ-peptide?2011

    • Author(s)
      Shinobu Kitazume
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Book] アルツハイマー病の原因酵素が糖鎖を変えていた、「糖鎖の生物機能の解明と利用技術」2009

    • Author(s)
      橋本康弘、北爪しのぶ
    • Total Pages
      12
    • Publisher
      蛋白質・核酸・酵素
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Book] アルツハイマー病の原因酵素が糖鎖を変えていた、「糖鎖の生物機能の解明と利用技術」2009

    • Author(s)
      橋本康弘、北爪しのぶ
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Book] ファルマシア2007

    • Author(s)
      北爪 しのぶ
    • Total Pages
      5
    • Publisher
      可溶型糖転移酵素:肝疾患バイオマーカーへの応用
    • Data Source
      KAKENHI-PROJECT-18570141
  • [Book] 可溶型糖転移酵素 : 肝疾患バイオマーカーヘの応用2007

    • Author(s)
      北爪しのぶ
    • Publisher
      フアルマシア
    • Data Source
      KAKENHI-PROJECT-18570141
  • [Book] ファルマシア2007

    • Author(s)
      北爪しのぶ
    • Total Pages
      5
    • Publisher
      可溶型糖転移酵素:肝疾患バイオマーカーへの応用
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-18570141
  • [Book] 可溶型糖転移酵素 : 肝疾患バイオマーカーへの応用2007

    • Author(s)
      北爪しのぶ
    • Publisher
      ファルマシア
    • Data Source
      KAKENHI-PROJECT-17046025
  • [Book] 糖鎖化学の新展開2005

    • Author(s)
      北爪しのぶ
    • Total Pages
      536
    • Publisher
      エヌ・ティー・エス社
    • Data Source
      KAKENHI-PROJECT-17046025
  • [Book] 糖鎖化学の新展開2005

    • Author(s)
      北爪しのぶ
    • Total Pages
      536
    • Publisher
      エヌ・ティー・エス社
    • Data Source
      KAKENHI-PROJECT-15770090
  • [Book] 糖鎖科学研究調査報告

    • Author(s)
      北爪しのぶ
    • Publisher
      川嵜 敏祐(印刷中)
    • Data Source
      KAKENHI-PROJECT-16015329
  • [Journal Article] Endothelial expression of human amyloid precursor protein leads to amyloid β in the blood and induces cerebral amyloid angiopathy in knock-in mice2022

    • Author(s)
      Tachida Yuriko、Miura Saori、Muto Yui、Takuwa Hiroyuki、Sahara Naruhiko、Shindo Akihiro、Matsuba Yukio、Saito Takashi、Taniguchi Naoyuki、Kawaguchi Yasushi、Tomimoto Hidekazu、Saido Takaomi、Kitazume Shinobu
    • Journal Title

      Journal of Biological Chemistry

      Volume: - Issue: 6 Pages: 101880-101880

    • DOI

      10.1016/j.jbc.2022.101880

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06896, KAKENHI-PUBLICLY-21H00446, KAKENHI-PROJECT-23K21399, KAKENHI-PROJECT-21H02831
  • [Journal Article] Recent advances in the modeling of Alzheimer’s disease.2022

    • Author(s)
      Sasaguri H, Hashimoto S, Watamura N, Sato K, Takamura R, Nagata K, Tsubuki S, Ohshima T, Yoshiki A, Sato K, Kumita W, Sasaki E, Kitazume S, Nilsson P, Winblad B, *Saito T, *Iwata N, *Saido TC
    • Journal Title

      Frontiers in Neuroscience

      Volume: 16 Pages: 8074743-8074743

    • DOI

      10.3389/fnins.2022.807473

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03564, KAKENHI-PROJECT-21K15378, KAKENHI-PROJECT-21H02831
  • [Journal Article] 1.Imamaki R. Ogawa K, Kizuka Y, Komi Y, Kojima S, Kotani N, Honke K, Honda T, Taniguchi N, and Kitazume S2018

    • Author(s)
      1.Imamaki R. Ogawa K, Kizuka Y, Komi Y, Kojima S, Kotani N, Honke K, Honda T, Taniguchi N, and Kitazume S
    • Journal Title

      Oncogene

      Volume: - Issue: 31 Pages: 4287-4299

    • DOI

      10.1038/s41388-018-0271-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08601, KAKENHI-PROJECT-18K06914, KAKENHI-WRAPUP-18H05199, KAKENHI-PROJECT-16K08591, KAKENHI-PROJECT-15K14481, KAKENHI-PROJECT-15H04700
  • [Journal Article] CD22-binding synthetic sialosides regulate B lymphocyte proliferation through CD22 ligand-dependent and independent pathways, and enhances antibody production in mice2018

    • Author(s)
      2.Matsubara N, Imamura A, Yonemiz Tu, Akatsu C, Yang H, Ueki A, Watanabe N, Abdu-Allah H, Numoto N, Takematsu H, Kitazume S, Tedder FT, Marth JD, Ito N, Ando H, Ishida H, Kiso M, and Tsubata T
    • Journal Title

      Frontiers in Immunology

      Volume: - Pages: 820-820

    • DOI

      10.3389/fimmu.2018.00820

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08601, KAKENHI-PROJECT-17K17695, KAKENHI-PROJECT-26293062, KAKENHI-PROJECT-18H03942
  • [Journal Article] High affinity sugar ligands of C-type lectin receptor langerin.2018

    • Author(s)
      Ota F, Hirayama T, Kizuka Y, Yamaguchi Y, Fujinawa R, Nagata M; Ismanto HS, Lepenies, Aretz J, Rademacher C, Seeberger PH; Angata T, Kitazume S, Yoshida K, Betsuyaku T, Kida K Yamasaki S, and Taniguchi N
    • Journal Title

      BBA - General Subjects

      Volume: - Issue: 7 Pages: 1592-1601

    • DOI

      10.1016/j.bbagen.2018.04.004

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08601, KAKENHI-PROJECT-17K07356, KAKENHI-PROJECT-18K06914, KAKENHI-PLANNED-26110009, KAKENHI-PROJECT-15K14481, KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-16H04758, KAKENHI-PROJECT-17H04087
  • [Journal Article] Glycosylation controls cooperative PECAM-VEGFR2-β3 integrin functions at the endothelial surface for tumor angiogenesis.2018

    • Author(s)
      1.Imamaki R. Ogawa K, Kizuka Y, Komi Y, Kojima S, Kotani N, Honke K, Honda T, Taniguchi N, and Kitazume S*.
    • Journal Title

      Oncogene

      Volume: 37 Pages: 4287-4299

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08601
  • [Journal Article] Reactivity of anti-HNK-1 antibodies to branched O-mannose glycans associated with demyelination.2017

    • Author(s)
      Sakuda K, Kizuka Y, Yamaguchi Y, Tanaka K, Ogiwara K, Segawa T, Hagiwara Y, Matsuo I, Ogawa H, Taniguchi N, and Kitazume S
    • Journal Title

      BBRC

      Volume: 487 Pages: 450-456

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K08601
  • [Journal Article] Core fucose is critical for CD14-dependent Toll-like receptor 4 signaling2017

    • Author(s)
      4.Iijima J, Kobayashi S, Kitazume S*, Kizuka Y, Fujinawa R, Korekane H, Shibata T, Saitoh S, Akashi-Takamura S, Miyake K, Miyoshi E, and Taniguch N
    • Journal Title

      Glycobiology

      Volume: 2017 Issue: 11 Pages: 1006-1015

    • DOI

      10.1093/glycob/cwx075

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08601, KAKENHI-PROJECT-15K14481, KAKENHI-PROJECT-26293083, KAKENHI-PROJECT-16H05226, KAKENHI-PROJECT-16K15253, KAKENHI-PROJECT-26860201, KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-15K09491
  • [Journal Article] Inhibitory Role of α2,6-Sialylation in Adipogenesis.2017

    • Author(s)
      Kaburagi T, Kizuka Y, Kitazume S, and Taniguchi N.
    • Journal Title

      J. Biol. Chem

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08601
  • [Journal Article] PECAM2017

    • Author(s)
      Kitazume S
    • Journal Title

      Encyclopedia in Signaling Molecules

      Volume: -

    • Data Source
      KAKENHI-PROJECT-16K08601
  • [Journal Article] Glyco-redox, a link between oxidative stress and changes of glycans: Lessons from research on glutathione, reactive oxygen and nitrogen species to glycobiology.2016

    • Author(s)
      N. Taniguchi, Y. Kizuka, S. Takamatsu, E. Miyoshi, C. Gao, K. Suzuki, S. Kitazume, K. Ohtsubo
    • Journal Title

      Arch. Biochem. Biphys.

      Volume: 595 Pages: 72-80

    • DOI

      10.1016/j.abb.2015.11.024

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-26117522, KAKENHI-PROJECT-25430122, KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-26430118, KAKENHI-PROJECT-15K14481
  • [Journal Article] Visualizing Trimming Dependence of Biodistribution and Kinetics with Homo- and Heterogeneous N-Glycoclusters on Fluorescent Albumin2016

    • Author(s)
      A. Ogura, T. Tahara, S. Nozaki, K. Morimoto, Y. Kizuka, S. Kitazume, M. Hara, S. Kojima, H. Onoe, A. Kurbangalieva, N. Taniguchi, Y. Watanabe, K. Tanaka
    • Journal Title

      Sci. Rep.

      Volume: 6 Issue: 1 Pages: 21797-21797

    • DOI

      10.1038/srep21797

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26560438, KAKENHI-PUBLICLY-26117522, KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-25430122, KAKENHI-PROJECT-25560410
  • [Journal Article] Bisecting GlcNAc modification stabilizes BACE1 protein under oxidative stress conditions2016

    • Author(s)
      Kizuka Y, Nakano M, Kitazume S, Saito T, Saido TC, Taniguchi N
    • Journal Title

      Biochemical Journal

      Volume: 473 Issue: 1 Pages: 21-30

    • DOI

      10.1042/bj20150607

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K14481, KAKENHI-PROJECT-26670148, KAKENHI-PUBLICLY-26110723, KAKENHI-PUBLICLY-26117522, KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-25430122, KAKENHI-PROJECT-26290019
  • [Journal Article] High-Sensitivity and Low-Toxicity Fucose Probe for Glycan Imaging and Biomarker Discovery.2016

    • Author(s)
      Kizuka Y, Funayama S, Shogomori H, Nakano M, Nakajima K, Oka R, Kitazume S, Yamaguchi Y, Sano M, Korekane H, Hsu TL, Lee HY, Wong CH, Taniguchi N.
    • Journal Title

      Cell Chemical Biology

      Volume: 23 Issue: 7 Pages: 782-792

    • DOI

      10.1016/j.chembiol.2016.06.010

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-26670148, KAKENHI-PROJECT-15K19016, KAKENHI-PROJECT-16K07998, KAKENHI-PROJECT-16H04758
  • [Journal Article] Cell surface and in vivo interaction of dendrimeric N-glycoclusters.2015

    • Author(s)
      M. Taichi, S. Kitazume, K. Vong, R. Imamaki, A. Kurbangalieva, N. Taniguchi, and K. Tanaka
    • Journal Title

      Glycoconjugate J.

      Volume: 32 Issue: 7 Pages: 497-503

    • DOI

      10.1007/s10719-015-9594-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-26117522, KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-25430122
  • [Journal Article] Clec4g (LSECtin) interacts with BACE1 and suppresses Aβ generation2015

    • Author(s)
      Kizuka Y, Kitazume S, Sato K, Taniguchi N
    • Journal Title

      FEBS Letters

      Volume: 589 Issue: 13 Pages: 1418-1422

    • DOI

      10.1016/j.febslet.2015.04.060

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K14481, KAKENHI-PROJECT-26670148, KAKENHI-PUBLICLY-26117522, KAKENHI-PROJECT-15H04700, KAKENHI-PROJECT-25430122
  • [Journal Article] An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer’s disease2015

    • Author(s)
      Yasuhiko Kizuka, Shinobu Kitazume, Reiko Fujinawa, Takashi Saito, Nobuhisa Iwata, Takaomi C. Saido, Miyako Nakano, Yoshiki Yamaguchi, Yasuhiro Hashimoto
    • Journal Title

      EMBO Mol. Med.

      Volume: 7(2) Issue: 2 Pages: 175-89

    • DOI

      10.15252/emmm.201404438

    • NAID

      120006799362

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-24110511, KAKENHI-PROJECT-24700371, KAKENHI-PROJECT-25293016, KAKENHI-PROJECT-25460054, KAKENHI-PUBLICLY-26110727, KAKENHI-PUBLICLY-26117522, KAKENHI-PROJECT-26460090, KAKENHI-PROJECT-26460394, KAKENHI-PROJECT-25430122
  • [Journal Article] A cascading reaction sequence involving ligand-directed azaelectrocyclization and autooxidation-induced fluorescence recovery enables visualization of target proteins on the surfaces of live cells.2014

    • Author(s)
      Tanaka, K., Kitadani, M., Tsutsui, A., Pradipta, AR., Imamaki, R., Kitazume, S., Taniguchi, N., Fukase K.
    • Journal Title

      Org Biomol Chem.

      Volume: 12 Issue: 9 Pages: 1412-1418

    • DOI

      10.1039/c3ob42267d

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23241074, KAKENHI-PROJECT-23681047, KAKENHI-PUBLICLY-24102518, KAKENHI-PROJECT-25430122, KAKENHI-PROJECT-25560410, KAKENHI-PROJECT-26560447
  • [Journal Article] Polyamine modification by acrolein exclusively produces 1,5-diazacyclooctanes: a previously unrecognized mechanism for acrolein-mediated oxidative stress2014

    • Author(s)
      Tsutsui A, Imamaki R, Kitazume S, Hanashima S, Yamaguchi Y, Kaneda M, Oishi S, Fujii N, Kurbangalieva A, Taniguchi N, Tanaka K
    • Journal Title

      Org Biomol Chem.

      Volume: 12 Issue: 28 Pages: 5151-5157

    • DOI

      10.1039/c4ob00761a

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-26117522
  • [Journal Article] Sweet role of platelet endothelial cell adhesion moleculr (PECAM) in understanding angiogenesis.2014

    • Author(s)
      S. Kitazume*, R. Imamaki, K. Ogawa, and N. Taniguchi
    • Journal Title

      Glycobiology

      Volume: 24 Issue: 12 Pages: 1260-1264

    • DOI

      10.1093/glycob/cwu094

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25430122, KAKENHI-PUBLICLY-26117522
  • [Journal Article] Interaction of platelet endothelial cell adhesion molecule (PECAM) with α2,6-sialylated glycan regulates its cell surface residency and anti-apoptotic role2014

    • Author(s)
      Kitazume, S., Imamaki, R., Kurimoto, A., Ogawa, K., Kato, M., Yamaguchi, Y., Tanaka, K., Ishida, H., Ando, H., Kiso, M., Hashii, N., Kawasaki, N. and Taniguchi, N.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 289 Issue: 40 Pages: 27604-27613

    • DOI

      10.1074/jbc.m114.563585

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-22380067, KAKENHI-PROJECT-23688014, KAKENHI-PROJECT-25430122, KAKENHI-PROJECT-25460054, KAKENHI-PUBLICLY-26110704, KAKENHI-PUBLICLY-26117522
  • [Journal Article] Identification of Ectonucleotide Pyrophosphatase/Phosphodiesterase 3 (ENPP3) as a Regulator of N-Acetylglucosaminyltransferase GnT-IX (GnT-Vb)2013

    • Author(s)
      Korekane H, Park JY, Matsumoto A, Nakajima K, Takamatsu S, Ohtsubo K, Miyamoto Y, Hanashima S, Kanekiyo K, Kitazume S, Yamaguchi Y, Matsuo I, Taniguchi N
    • Journal Title

      J. Biol. Chem.

      Volume: 288(39) Issue: 39 Pages: 27912-27926

    • DOI

      10.1074/jbc.m113.474304

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249018, KAKENHI-PROJECT-23501303, KAKENHI-PROJECT-24659111, KAKENHI-PROJECT-25430122
  • [Journal Article] Soluble amyloid precursor protein 770 is a novel biomarker candidate for acute coronary syndrome2013

    • Author(s)
      Kitazume S, Yoshihisa A, Yamaki T, Oikawaa M, Tachida Y, Ogawa K, Imamaki R, Takeishi Y, Yamamoto N, Taniguchi N
    • Journal Title

      Proteomics Clinical Applications

      Volume: 7 Issue: 9-10 Pages: 657-663

    • DOI

      10.1002/prca.201200135

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591100, KAKENHI-PROJECT-25430122, KAKENHI-PROJECT-25860613
  • [Journal Article] Loss of branched O-mannosyl glycans in astrocytes accelerates remyelination2013

    • Author(s)
      Kanekiyo K, Inamori K, Kitazume S, Sato K, Maeda J, Higuchi M, Kizuka Y, Korekane H, Matsuo I, Honke K, Taniguchi N
    • Journal Title

      J. Neurosci.

      Volume: 33(24) Issue: 24 Pages: 10037-10047

    • DOI

      10.1523/jneurosci.3137-12.2013

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20249018, KAKENHI-PLANNED-23111009, KAKENHI-PROJECT-23390235, KAKENHI-PROJECT-25430122, KAKENHI-PROJECT-25670166
  • [Journal Article] Mass isotopomer analysis of metabolically labeled nucleotide sugars and N-and o-glycans for tracing nucleotide sugar metabolisms2013

    • Author(s)
      Nakajima K, Ito E, Ohtsubo K, Shirato K, Takamiya R, Kitazume S, Angata T, Taniguchi N
    • Journal Title

      Mol. Cell Proteomics

      Volume: 12(9) Issue: 9 Pages: 2468-2480

    • DOI

      10.1074/mcp.m112.027151

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20249018, KAKENHI-PROJECT-24790593, KAKENHI-PROJECT-25430122
  • [Journal Article] How does N. and O-glycosylation affect the formation and accumulation of Amyloidβ-peptide?2011

    • Author(s)
      S. Kitazume
    • Journal Title

      Trends in Glycoscience and Glycotechnology

      Volume: 23 Pages: 161-167

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Journal Article] A unique N-glycan on human transferrin in CSF : a possible biomarker for iNPH2011

    • Author(s)
      S. Futakawa, K. Nara, M. Miyajima, A. Kuno, H. Ito, H. Kaji, K. Shirotani, T. Honda, Y. Tohyama, K. Hoshi, Y. Hanzawa, S. Kitazume, R. Imamaki, K. Furukawa, K. Tasaki, H. Arai, T. Yuasa, M. Abe, H. Arai, H. Narimatsu, and Y. Hashimoto
    • Journal Title

      Neurobiol. Aging

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Journal Article] Brain-specific expression of N-acetylglucosaminyltransferase IX (GnT-IX) is regulated by epigenetic histone modifications2011

    • Author(s)
      Y.Kizuka, S.Kitazume, M.Yoshida, N.Taniguchi
    • Journal Title

      J.Biol.Chem.

      Volume: 286 Issue: 36 Pages: 31875-31884

    • DOI

      10.1074/jbc.m111.251173

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570154, KAKENHI-PROJECT-23770163
  • [Journal Article] Brain-specific expression of N-acetylglucosaminyltransferase IX(GnT-IX) is regulated by epigenetic histone modifications2011

    • Author(s)
      Y. Kizuka, S. Kitazume, M. Yoshida, and N. Taniguchi
    • Journal Title

      Biol. Chem.

      Volume: 286 Pages: 31875-31884

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Journal Article] Brain endothelial cells produce amyloid β from amyloid precursor protein 770 and preferentially secrete the O-glycosylated form2010

    • Author(s)
      S.Kitazume, Y.Tachida, M.Kato, Y.Yamaguchi, T.Honda, Y.Hashimoto, Y.Wada, T.Saito, N.Iwata, T.Saido, N, Taniguchi
    • Journal Title

      J.Biol.Chem.

      Volume: 285 Pages: 40097-40103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Journal Article] Regulates Its Homophilic Interactions and Downstream Antiapoptotic Signaling2010

    • Author(s)
      S.Kitazume, R.Imamaki, K.Ogawa, Y.Komi, S.Futakawa, S.Kojima, Y.Hashimoto, J.D.Marth, J.C.Paulson, N.Taniguchi
    • Journal Title

      J.Biol.Chem. 285(In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Journal Article] α2, 6-Sialic Acid on Platelet Endotheli al Cell Adhesion Molecule(PECAM) Regulates its homophilic interactio ns and downstream antiapoptotic si gnaling2010

    • Author(s)
      S. Kitazume, R. Imamaki, K. Ogaw a, Y. Komi, S. Futakawa, S. Kojima, Y. Hashimoto, J. D. Marth, J. C. Paulson, and N. Taniguchi
    • Journal Title

      J. Biol. Chem.

      Volume: 285 Pages: 6515-6521

    • URL

      http://www.functionalglycomics.org/fg/update/2010/100211/full/fg.2010.8.shtml

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Journal Article] Brain endothelial cells produce amyloidβfrom amyloid precursor protein 770 and preferentially secrete the O-glycosylated form2010

    • Author(s)
      S. Kitazume, Y. Tachida, M. Kato, Y. Yamaguchi, T. Honda, Y. Hashimoto, Y. Wada, T. Saito, N. Iwata, T. Saido and N, Taniguchi
    • Journal Title

      J. Biol. Chem.

      Volume: 285 Pages: 40097-40103

    • URL

      http://www.functionalglycomics.org/fg/update/2010/101111/full/fg.2010.36.shtml

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Journal Article] Simultaneous determination of nucleotide sugars involved in glycosylation with ion-pair reversed-phase HPLC2010

    • Author(s)
      K.Nakajima, S.Kitazume, T.Angata, R.Fujinawa, E.Miyoshi, N.Taniguchi
    • Journal Title

      Glycobiology

      Volume: 20 Pages: 865-871

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Journal Article] Simultaneous determination of nucleotide sugars involved in glycosylation with ion-pair reversed. phase HPLC2010

    • Author(s)
      K. Nakajima, S. Kitazume, T. Angata, R. Fujinawa, E. Miyoshi, and N. Taniguchi
    • Journal Title

      Glycobiology

      Volume: 20 Pages: 865-871

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Journal Article] α2, 6-Sialic Acid on Platelet Endothelial Cell Adhesion Molecule (PECAM) Regulates Its Homophilic Interactions and Downstream Antiapoptotic Signaling2010

    • Author(s)
      S.Kitazume, R.Imamaki, K.Ogawa, Y.Komi, S.Futakawa, S.Kojima, Y.Hashimoto, J.D.Marth, J.C.Paulson, N.Taniguchi
    • Journal Title

      J.Biol.Chem

      Volume: 285 Pages: 6515-6521

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Journal Article] Development of sandwich enzyme-linked immunosorbent assay systems for plasmaβ-galactosideα2, 6-sialyltransferase, a possible hepatic disease biomarker2009

    • Author(s)
      S. Futakawa, S. Kitazume, R. Oka, K. Ogawa, Y. A. Kinoshita, K. Miyashita and Y. Hashimoto
    • Journal Title

      Analytica Chimica Acta

      Volume: 531 Pages: 116-120

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Journal Article] Development of sandwich enzyme-linked immunosorbent assay systems for plasma β-galactoside α2, 6-sialyltransferase, a possible hepatic disease biomarker2009

    • Author(s)
      S.Futakawa, S.Kitazume, R.Oka, K.Ogawa, Y.A.Kinoshita, K.Miyashita, Y.Hashimoto
    • Journal Title

      Analytica Chimica Acta 531

      Pages: 116-120

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Journal Article] Molecular insights into β-galactoside α2, 6-sialyltransferase secretion in vivo2009

    • Author(s)
      S.Kitazume, R.Oka, K.Ogawa, S.Futakawa, Y.Hagiwara, H.Takigawa, M.Kato, A.Kasahara, E.Miyoshi, N.Taniguchi, Y.Hashimoto
    • Journal Title

      Glycobiology 19

      Pages: 479-487

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Journal Article] Molecular insights intoβ-galactosideα2, 6-sialyltransferase secretion in vivo2009

    • Author(s)
      S. Kitazume#, R. Oka, K. Ogawa, S. Futakawa, Y. Hagiwara, H. Takigawa, M. Kato, A. Kasahara, E. Miyoshi, N. Taniguchi, and Y. Hashimoto
    • Journal Title

      Glycobiology

      Volume: 19 Pages: 479-487

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Journal Article] ST6Gal I cleavage by BACE1 enhances the sialylation of soluble glycoproteins: A novel regulatory mechanism for α2,6-sialylation2007

    • Author(s)
      I. Sugimoto, S. Futakawa, R. Oka, K. Ogawa, J.D. Marth, E. Miyoshi, N. Taniguchi, Y. Hashimoto, and S. Kitazume
    • Journal Title

      J. Biol. Chem. 282

      Pages: 34896-34903

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18570141
  • [Journal Article] Regulation of heparan sulfate 6-O-sulfation by β-secretase activity2007

    • Author(s)
      Nagai, H. Habuchi, S. Kitazume, H. Toyoda, Y. Hashimoto, K. Kimata
    • Journal Title

      J. Biol. Chem. 282

      Pages: 14942-14951

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570141
  • [Journal Article] ST6Gal I cleavage by BACE1 enhances the sialylation of soluble glycoproteins : A novel regulatory mechanism for α2, 6-sialylation N.2007

    • Author(s)
      I. Sugimoto, S. Futakawa, R. Oka, K. Ogawa, J. D. Marth, E. Miyoshi, N. Taniguchi, Y. Hashimoto, S. Kitazume
    • Journal Title

      J. Biol. Chem. 282

      Pages: 34896-34903

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570141
  • [Journal Article] Regulation of heparan sulfate 6-O-sulfation by β-secretase activity2007

    • Author(s)
      N. Nagai, H. Habuchi, S. Kitazume, H. Toyoda, Y. Hashimoto, and K. Kimata
    • Journal Title

      J. Biol. Chem. 282

      Pages: 14942-14951

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18570141
  • [Journal Article] ST6Gal I cleavage by BACE1 enhances the sialylation of soluble glycoproteins : A novel regulatory mechanism for α2,6-sialylation2007

    • Author(s)
      I. Sugimoto, S. Futakawa, R. Oka, K. Ogawa, J. D. Marth, E. Miyoshi, N. Taniguchi, Y. Hashimoto, and S. Kitazume
    • Journal Title

      J. Biol. Chem. 282

      Pages: 34896-34903

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18570141
  • [Journal Article] Screening a series of sialyltransferases for possible BACE1 substrates2006

    • Author(s)
      S.Kitazume, Y.Tachida, R.Oka, K.Nakagawa, S.Takashima Y-C.Lee, Y.Hashimoto
    • Journal Title

      Glycoconjugate J (in press)

    • Data Source
      KAKENHI-PROJECT-15770090
  • [Journal Article] Sialylation enhances the secretion of neurotoxic amyloid-β-peptides2006

    • Author(s)
      K.Nakagawa, S.Kitazume, R.Oka, K.Maruyama, T.C.Saido, Y.Sato, T.Endo, Y.Hashimoto
    • Journal Title

      J.Neurochem. 96

      Pages: 924-933

    • Data Source
      KAKENHI-PROJECT-18570141
  • [Journal Article] Sialylation enhances the secretion of neurotoxic amyloid-β-peptides2006

    • Author(s)
      K.Nakagawa, S.Kitazume, R.Oka, K.Maruyama, T.C.Saido, Y.Sato, T.Endo, Y.Hashimoto
    • Journal Title

      J.Neurochem. (In press)

    • Data Source
      KAKENHI-PROJECT-17046025
  • [Journal Article] Sialylation enhances the secretion of neurotoxic amyloid-β-peptides2006

    • Author(s)
      K.Nakagawa, S.Kitazume, R.Oka, K.Maruyama, T.C.Saido, Y.Sato, T.Endo, Y.Hashimoto
    • Journal Title

      J.Neurochem. (In press)

    • Data Source
      KAKENHI-PROJECT-15770090
  • [Journal Article] Screening a series of sialyltransferases for possible BACE1 substrates2006

    • Author(s)
      S.Kitazume, Y.Tachida, R.Oka, K.Nakagawa, S.Takgashima, Y-C.Lee, Y.Hashimoto
    • Journal Title

      Glycoconjugate J. 23

      Pages: 437-441

    • Data Source
      KAKENHI-PROJECT-17046025
  • [Journal Article] Screening a series of sialyltransferases for possible BACE1 substrates2006

    • Author(s)
      S.Kitazume, Y.Tachida, R.Oka, K.Nakagawa, S.Takashima, Y-C.Lee, Y.Hashimoto
    • Journal Title

      Glycoconjugate J (in press)

    • Data Source
      KAKENHI-PROJECT-17046025
  • [Journal Article] Screening a series of sialyltransferases for possible BACE1 substrates2006

    • Author(s)
      S.Kitazume, Y.Tachida, R.Oka, K.Nakagawa, S.Takashima, Y・C.Lee, Y.Hashimoto
    • Journal Title

      Glycoconjugate J. 23

      Pages: 437-441

    • Data Source
      KAKENHI-PROJECT-18570141
  • [Journal Article] Sialylation enhances the secretion of neurotoxic amyloid-β-peptides2006

    • Author(s)
      K.Nakagawa, S.Kitazume, R.Oka, K.Maruyama, T.C.Saido, Y.Sato, T.Endo, Y.Hashimoto
    • Journal Title

      J. Neurochem. 96

      Pages: 924-933

    • Data Source
      KAKENHI-PROJECT-17046025
  • [Journal Article] Involvement of proteases in glycosyltransferase secretion : Alzheimer's beta-secretase-dependent cleavage and a following processing by an aminopeptidase2005

    • Author(s)
      S.Kitazume, M.Suzuki, T.C.Saido, Y.Hashimoto
    • Journal Title

      Glycoconjugate J. 21

      Pages: 25-29

    • Data Source
      KAKENHI-PROJECT-15770090
  • [Journal Article] Characterization of Drosophila aspartic proteases that induce the secretion of a Golgi-resident transferase, heparan sulfate 6-O-sulfotransferase.2005

    • Author(s)
      Norihiro Kotani, S.Kitazume
    • Journal Title

      J. Biochem (In press)

    • Data Source
      KAKENHI-PROJECT-15040224
  • [Journal Article] Characterization of Drosophila aspartic proteases that induce the secretion of a Golgi-resident transferase, heparan sulfate 6-O-sulfotransferase.2005

    • Author(s)
      Norihiro Kotani, S.Kitazume
    • Journal Title

      J.Biochem. (In press)

    • Data Source
      KAKENHI-PROJECT-15770090
  • [Journal Article] Involvement of proteases in glycosyltransferase secretion : Alzheimer's beta-secretase-dependent cleavage and a following processing by an aminopeptidase2005

    • Author(s)
      S.Kitazume, M.Suzuki, T.C.Saido, Y.Hashimoto
    • Journal Title

      Glycoconjugate J. 21

      Pages: 25-29

    • Data Source
      KAKENHI-PROJECT-17046025
  • [Journal Article] In vivo cleavage of α2,6-sialyltransferase by Alzheimer's β-secretase2005

    • Author(s)
      S.Kitazume
    • Journal Title

      J.Biol.Chem. 290

      Pages: 8589-8595

    • Data Source
      KAKENHI-PROJECT-15770090
  • [Journal Article] In vivo cleavage of α2,6-sialyltransferase by Alzheimer's β-secretase2005

    • Author(s)
      S.Kitazume
    • Journal Title

      J.Biol.Chem. 200

      Pages: 8589-8595

    • Data Source
      KAKENHI-PROJECT-15040224
  • [Journal Article] In vivo cleavage of alpha2,6-sialyltransferase by Alzheimer beta-secretase (BACE1)2005

    • Author(s)
      S.Kitazume
    • Journal Title

      J.Biol.Chem. 280

      Pages: 8589-8595

    • Data Source
      KAKENHI-PROJECT-16015329
  • [Journal Article] Characterization of Drosophila aspartic proteases that induce the secretion of a Golgi-resident transferase, heparan sulfate 6-O-sulfotransferase2005

    • Author(s)
      Norihiro Kotani, S.Kitazume, Keisuke Kamimura, Satomi Takeo, Toshiro Aigaki, Hiroshi Nakato, Yasuhiro Hashimoto
    • Journal Title

      J.Biochem. 137

      Pages: 315-322

    • Data Source
      KAKENHI-PROJECT-17046025
  • [Journal Article] In vivo cleavage of α2,6-sialyltransferase by Alzheimer's β-secretase2005

    • Author(s)
      S.Kitazume, K.Nakagawa, R.Oka, Y.Tachida, K.Ogawa, Y.Luo, M.Citron, H.Shitara, C.Taya, H.Yonekawa, J.C.Paulson, E.Miyoshi, N.Taniguchi, Y.Hashimoto
    • Journal Title

      J.Biol.Chem. 280

      Pages: 8589-8595

    • Data Source
      KAKENHI-PROJECT-17046025
  • [Journal Article] In vivo cleavage of α2,6-sialyltransferase by Alzheimer's β-secretase2005

    • Author(s)
      S.Kitazume, K.Nakagawa, R.Oka, Y.Tachida, K.Ogawa, Y.Luo, M.Citron, H.Shitara, C.Taya, H.Yonekawa, J.C.Paulson, E.Miyoshi, N.Taniguchi, Y.Hashimoto
    • Journal Title

      J.Biol.Chem. 280

      Pages: 8589-8595

    • Data Source
      KAKENHI-PROJECT-15770090
  • [Journal Article] In vivo cleavage of alhpa2,6-sialyltransferase by Alzheimer's beta-secretase (BACE1)2005

    • Author(s)
      S.Kitazume, et al.
    • Journal Title

      J.Biol.Chem 280

      Pages: 8589-8595

    • Data Source
      KAKENHI-PROJECT-17025047
  • [Journal Article] Characterization of Drosophila aspartic proteases that induce the secretion of a Golgi-resident transferase, heparan sulfate 6-O-sulfotransferase2005

    • Author(s)
      Norihiro Kotani, S.Kitazume, Keisuke Kamimura, Satomi Takeo, Toshiro Aigaki, Hiroshi Nakato, Yasuhiro Hashimoto
    • Journal Title

      J.Biochem. 137

      Pages: 315-322

    • Data Source
      KAKENHI-PROJECT-15770090
  • [Journal Article] アルツハイマー病ベータセクレターゼの基質としての糖転移酵素2004

    • Author(s)
      北爪しのぶ
    • Journal Title

      蛋白質核酸酵素 49

      Pages: 2468-2469

    • Data Source
      KAKENHI-PROJECT-15040224
  • [Journal Article] 肝炎モデルラットにおけるシアル酸転移酵素の分泌2004

    • Author(s)
      北爪しのぶ
    • Journal Title

      Functional Glycomics News Letter 糖鎖フラッシュ号 4

      Pages: 17-19

    • Data Source
      KAKENHI-PROJECT-15770090
  • [Journal Article] アルツハイマー病βセクレターゼの基質としての糖転移酵素2004

    • Author(s)
      北爪しのぶ
    • Journal Title

      蛋白質核酸酵素 49

      Pages: 2468-2472

    • Data Source
      KAKENHI-PROJECT-16015329
  • [Journal Article] Involvement of proteases in glycosyltransferase secretion : Alzheimer's beta-secretase-dependent cleavage and a following processing by an aminopeptidase.2004

    • Author(s)
      S.Kitazume
    • Journal Title

      Glycoconjugate J. 21

      Pages: 25-29

    • Data Source
      KAKENHI-PROJECT-15040224
  • [Journal Article] アルツハイマー病ベータセクレターゼの基質としての糖転移酵素2004

    • Author(s)
      北爪しのぶ
    • Journal Title

      蛋白質核酸酵素 49

      Pages: 2468-2469

    • Data Source
      KAKENHI-PROJECT-15770090
  • [Journal Article] 肝炎モデルラットにおけるシアル酸転移酵素の分泌2004

    • Author(s)
      北爪しのぶ
    • Journal Title

      Functional Glycomics News Letter糖鎖フラッシュ号 4

      Pages: 17-19

    • Data Source
      KAKENHI-PROJECT-15040224
  • [Journal Article] Involvement of proteases in glycosyltransferase secretion : Alzheimer's beta-secretase-dependent cleavage and a following processing by an aminopeptidase.2004

    • Author(s)
      S.Kitazume
    • Journal Title

      Glycoconjugate J. 21

      Pages: 25-29

    • Data Source
      KAKENHI-PROJECT-15770090
  • [Journal Article] Integrated approach toward the discovery of glyco-biomarkers of in flammation-related diseases

    • Author(s)
      Takashi Angata, Reiko Fujinawa, Ayako Kurimoto, Kazuki Nakajima, Masaki Kato, Shinji Takamatsu, Hiroaki Korekane, Cong-Xiao Gao, Kazuaki Ohtsubo, Shinobu Kitazume, Naoyuki Taniguchi
    • Journal Title

      Annals of New York Academy of Sciences

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Journal Article] High Throughput ELISAs to Measure a Unique Glycan on Transferrin in Cerebrospinal Fluid : A Possible Extension toward Alzheimer's Disease Biomarker Development

    • Author(s)
      K.Shirotani, S.Futakawa, K.Nara, K.Hoshi, T.Saito, Y.Tohyama, S.Kitazume, T.Yuasa, M.Miyajima, H, Arai, A.Kuno, H.Narimatsu, Y.Hashimoto
    • Journal Title

      International Journal of Alzheimer's Disease

      Volume: (In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Patent] 多発性硬化症マーカー2018

    • Inventor(s)
      北爪しのぶ、作田香子、谷口直之、橋本康弘、本多たかし、斎藤清
    • Industrial Property Rights Holder
      北爪しのぶ、作田香子、谷口直之、橋本康弘、本多たかし、斎藤清
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-028329
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-16K08601
  • [Patent] 認知症診断の為の可溶型アミロイドβ前駆体タンパク質770β切断産物の検出方法2016

    • Inventor(s)
      北爪しのぶ、谷口直之、立田由里子、西道隆臣、橋本康弘、本多たかし
    • Industrial Property Rights Holder
      北爪しのぶ、谷口直之、立田由里子、西道隆臣、橋本康弘、本多たかし
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016-04-22
    • Acquisition Date
      2017-01-22
    • Data Source
      KAKENHI-PROJECT-16K08601
  • [Patent] 認知症診断の為の可溶型アミロイドβ前駆体タンパク質770β切断産物の検出方法2011

    • Inventor(s)
      北爪しのぶ、谷口直之、立田由里子、西道隆臣、橋本康弘、本多たかし
    • Industrial Property Rights Holder
      理化学研究所
    • Filing Date
      2011-07-29
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Patent] 認知症診断の為の可溶型アミロイドβ前駆体タンパク質770β切断産物の検出方法2011

    • Inventor(s)
      北爪しのぶ、谷口直之、立田由里子、西道隆臣、橋本康弘、本多たかし
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Industrial Property Number
      2010-171122
    • Filing Date
      2011-07-29
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Patent] 認知症診断の為の可溶型アミロイドβ前駆体タンパク質770'β切断産物の検出方法2011

    • Inventor(s)
      北爪しのぶ、谷口直之、立田由里子、西道隆臣、橋本康弘、本多たかし
    • Industrial Property Rights Holder
      理化学研究所
    • Filing Date
      2011-07-29
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Patent] 認知症診断の為の可溶型アミロイドβ前駆体タンパク質770β切断産物の検出方法2010

    • Inventor(s)
      北爪しのぶ、谷口直之、立田由里子、西道隆臣、橋本康弘、本多たかし
    • Industrial Property Rights Holder
      理化学研究所
    • Acquisition Date
      2010-07-29
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Patent] 肝細胞癌の診断方法2006

    • Inventor(s)
      橋本康弘, 北爪しのぶ, 岡律子, 萩原良明, 木下憲明, 三善英知, 谷口直之
    • Industrial Property Rights Holder
      理化学研究所, 国立大学法人大阪大学, 株式会社免疫生物研究所
    • Industrial Property Number
      2006-156167
    • Filing Date
      2006-06-05
    • Data Source
      KAKENHI-PROJECT-17046025
  • [Patent] 肝細胞癌の診断方法2006

    • Inventor(s)
      橋本康弘, 北爪しのぶ, 岡律子, 萩原良明, 木下憲明, 三善英知, 谷口直之
    • Industrial Property Rights Holder
      独立行政法人理化学研究所, 国立大学法人大阪大学, 株式会社免疫生物研究所
    • Industrial Property Number
      2006-156167
    • Filing Date
      2006-06-05
    • Data Source
      KAKENHI-PROJECT-18570141
  • [Patent] 血清糖蛋白質をバイオマーカーとするアルツハイマー病の診断方法2005

    • Inventor(s)
      北爪 しのぶ, 岡 律子, 佐藤 雄治, 遠藤 玉夫, 樋口 真人, 荒井 啓行, 西道 隆臣, 橋本 康弘
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Industrial Property Number
      2005-138070
    • Filing Date
      2005-05-11
    • Data Source
      KAKENHI-PROJECT-17025047
  • [Patent] 血清糖蛋白質をバイオマーカーとするアルツハイマー病の診断方法2005

    • Inventor(s)
      北爪 しのぶ, 立田 由里子, 岡 律子, 橋本 康弘
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Industrial Property Number
      2005-138070
    • Filing Date
      2005-05-11
    • Data Source
      KAKENHI-PROJECT-17046025
  • [Patent] 血清糖蛋白質をバイオマーカーとするアルツハイマー病の診断方法2005

    • Inventor(s)
      北爪 しのぶ, 立田 由里子, 岡 律子, 橋本 康弘
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Industrial Property Number
      2005-138070
    • Filing Date
      2005-05-11
    • Data Source
      KAKENHI-PROJECT-15770090
  • [Patent] アルツハイマー病診断方法2004

    • Inventor(s)
      北爪 しのぶ, 西道 隆臣, 立田 由里子, 岡 律子, 橋本 康弘
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Industrial Property Number
      2003-382374
    • Filing Date
      2004-11-12
    • Data Source
      KAKENHI-PROJECT-16015329
  • [Presentation] Endothelial O-GalNAc glycosylation pathway determines APP processing for vascular Aβ deposition2017

    • Author(s)
      Kitazume S
    • Organizer
      AD/PD2016
    • Place of Presentation
      ウイーン(オーストリア)
    • Year and Date
      2017-03-30
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08601
  • [Presentation] How glycosylation affects amyloid beta production?2017

    • Author(s)
      Kitazume S
    • Organizer
      Glyconeuro 1st
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08601
  • [Presentation] Endothelial glycan is an attractive therapeutic target2017

    • Author(s)
      Kitazume S
    • Organizer
      RIKEN International symposium Systems Glycobiology and Beyond
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08601
  • [Presentation] Physiological and pathological roles of bisecting GlcNAc2016

    • Author(s)
      Kizuka Y., Nakano M., Kitazume S., Taniguchi N.
    • Organizer
      RIKEN-Max Planck Joint Research Center for Systems Chemical Biology, The fifth symposium
    • Place of Presentation
      ベルリン(ドイツ)
    • Year and Date
      2016-04-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670148
  • [Presentation] アミロイド産生と脳アミロイド アンギオパチーを規定する 血管内皮細胞のO-GalNAc型糖鎖2016

    • Author(s)
      北爪しのぶ
    • Organizer
      第35回日本糖質学会
    • Place of Presentation
      高知市文化プラザ(高知県・高知市)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08601
  • [Presentation] アルツハイマー病を促進させるバイセクト糖鎖2016

    • Author(s)
      木塚康彦、北爪しのぶ、谷口直之
    • Organizer
      第89回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-09
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670148
  • [Presentation] Bisecting GlcNAc糖鎖修飾とアルツハイマー病に関する研究2016

    • Author(s)
      木塚康彦、北爪しのぶ、谷口直之
    • Organizer
      第57回日本生化学会 中国・四国支部例会
    • Place of Presentation
      高知大学(高知)
    • Year and Date
      2016-05-27
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670148
  • [Presentation] Bisecting GlcNAc regulates Alzheimer’s Disease development2015

    • Author(s)
      Kizuka Y, Kitazume S, Nakano M, Saido T, Yamaguchi Y, Yoshida M, Hashimoto Y, Endo T, Taniguchi N
    • Organizer
      4th Austria-Japan Seminar for Comparative and Developmental Glycobiology
    • Place of Presentation
      Split (Croatia)
    • Year and Date
      2015-09-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670148
  • [Presentation] Bisecting GlcNAcは酸化ストレスによるBACE1の発現誘導を制御する2015

    • Author(s)
      木塚康彦、北爪しのぶ、谷口直之
    • Organizer
      第2回FCCAシンポジウムFCCAグライコサイエンス若手フォーラム2015
    • Place of Presentation
      東京
    • Year and Date
      2015-07-30
    • Data Source
      KAKENHI-PROJECT-26670148
  • [Presentation] BACE1のbisecting GlcNAc修飾によるアルツハイマー病の発症メカニズム2015

    • Author(s)
      木塚康彦、北爪しのぶ、中の三弥子、西道隆臣、橋本康弘、遠藤玉夫、谷口直之
    • Organizer
      第88回日本生化学会大会 第38回日本分子生物学会年会 合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670148
  • [Presentation] Bisecting GlcNAcによるBACE1の分解制御メカニズム2015

    • Author(s)
      木塚康彦、中の三弥子、北爪しのぶ、斉藤貴志、西道隆臣、谷口直之
    • Organizer
      GlycoTOKYO2015シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2015-10-24
    • Data Source
      KAKENHI-PROJECT-26670148
  • [Presentation] Bisecting GlcNAc on BACE1 is a Novel Therapeutic Target for Alzheimer’s Disease2015

    • Author(s)
      Kizuka Y, Kitazume S, Nakano M, Saido T, Hashimoto Y, Endo T, Taniguchi N
    • Organizer
      XXIII International Symposium on Glycoconjugates.
    • Place of Presentation
      Split (Croatia)
    • Year and Date
      2015-09-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670148
  • [Presentation] Bisecting GlcNAc modification is a novel therapeutic target for Alzheimer’s disease2015

    • Author(s)
      Kizuka Y, Kitazume S, Saido T, Nakano M, Ohnuki T, Shirouzu M, Yoshida M, Zegzouti H, Endo T, Taniguchi N
    • Organizer
      RIKEN-Max Planck Joint Research Center for Systems Chemical Biology, The 4th symposium
    • Place of Presentation
      神戸
    • Year and Date
      2015-05-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670148
  • [Presentation] Interaction of PECAM with α,2,6-sialylated glycan regulates its cell surface residency and anti-apoptotic role2014

    • Author(s)
      1.S. Kitazume
    • Organizer
      RIKEN-Max Planck Joint Research Center for Systems Chemical Biology (3rd Annual Symposium)
    • Place of Presentation
      Kreuth, Germany
    • Year and Date
      2014-05-23
    • Invited
    • Data Source
      KAKENHI-PROJECT-25430122
  • [Presentation] Brain endothelial cells produce amyloid β from amyloid precursor protein 770 and preferentially secrete the O-glycosylated form2011

    • Author(s)
      Shinobu Kitazume
    • Organizer
      第32回日本生化学会シンポジウム
    • Place of Presentation
      京都(招待講演)
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Presentation] Brain endothelial cells produce amyloidβfrom amyloid precursor protein 770 and preferentially secrete the O-glycosylated form2011

    • Author(s)
      S. Kitazume
    • Organizer
      第32回日本生化学会シンポジウム
    • Place of Presentation
      京都
    • Year and Date
      2011-09-22
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Presentation] Brain endothelial cells produce amyloid b from amyloid precursor protein 770 and preferentially secrete the O-glycosylated form2010

    • Author(s)
      S. Kitazume
    • Organizer
      Glyco Tokyo 2010
    • Place of Presentation
      Tokyo
    • Year and Date
      2010-07-30
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Presentation] Anα2, 6-Sialic Acid on Platelet Endothelial Cell Adhesion Molecule(PECAM) Regulates Its Homophilic Interactions and Downstream Anti-apoptotic Signaling2010

    • Author(s)
      S. Kitazume
    • Organizer
      Joint Japan-CCRC Symposium : New insights into the dynamic functions of glycans
    • Place of Presentation
      Athens(U. S. A)
    • Year and Date
      2010-03-05
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Presentation] α2, 6-Sialic Acid on Platelet Endothelial Cell Adhesion Molecule(PECAM) Regulates Its Homophilic Interactions and Downstream Antiapoptotic Signaling2010

    • Author(s)
      S. Kitazume
    • Organizer
      The 2nd Japan/China Joint Symposium on Glycobiology
    • Place of Presentation
      Wako
    • Year and Date
      2010-04-06
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Presentation] Brain endothelial cells produce amyloid β from amyloid precursor protein 770 and preferentially secrete the O-glycosylated form2010

    • Author(s)
      Shinobu Kitazume
    • Organizer
      GlycoT2010
    • Place of Presentation
      東京都・浅草
    • Year and Date
      2010-07-30
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Presentation] α2, 6-Sialic Acid on Platelet Endothelial Cell Adhesion Molecule(PECAM) Regulates Its Homophilic Interactions and Downstream Antiapoptotic Signaling2010

    • Author(s)
      S. Kitazume, R. Imamaki, K. Ogawa, Y. Komi, S. Futakawa, S. Kojima, Y. Hashimoto, J. D. Marth, J. C. Paulson, and N. Taniguchi
    • Organizer
      ICS2010
    • Place of Presentation
      Chiba
    • Year and Date
      2010-08-08
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Presentation] α2, 6-Sialic Acid on Platelet Endothelial Cell Adhesion Molecule (PECAM) Regulates Its Homophilic Interactions and Downstream Antiapoptotic Signaling2010

    • Author(s)
      S.Kitazume, R.Imamaki, K.Ogawa, Y.Komi, S.Futakawa, S.Kojima, Y.Hashimoto, J.D.Marth, J.C.Paulson, N.Taniguchi
    • Organizer
      ICS2010
    • Place of Presentation
      千葉県・幕張
    • Year and Date
      2010-08-08
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Presentation] 血管新生におけるα2, 6-シアル酸の役割2009

    • Author(s)
      北爪しのぶ、今牧理恵、小川加寿子、小見悠介、小嶋聡一、橋本康弘、Jamey D.Marth、谷口直之
    • Organizer
      第29回日本糖質学会
    • Place of Presentation
      飛騨・世界生活文化センター(岐阜)
    • Year and Date
      2009-09-09
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Presentation] Sialic acid-based homophilic PECAM interactions regulate pathological angiogenesis2009

    • Author(s)
      北爪しのぶ
    • Organizer
      第32回日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2009-12-10
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Presentation] 血管新生におけるα2, 6-シアル酸の役割2009

    • Author(s)
      北爪しのぶ、今牧理恵、小川加寿子、小見悠介、小嶋聡一、橋本康弘、Jamey D. Marth、谷口直之
    • Organizer
      第29回日本糖質学会
    • Place of Presentation
      飛騨
    • Year and Date
      2009-09-09
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Presentation] Sialic acid-based homophilic PECAM interactions regulate pathological angiogenesis2009

    • Author(s)
      S. Kitazume
    • Organizer
      第32回日本分子生物学会シンポジウム
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-10
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Presentation] Sialic acid-based homophilic PECAM interactions and pathological angiogenesis2009

    • Author(s)
      Shinobu Kitazume, Rie Imamaki, Kazuko Ogawa, Yusuke Komi, Satoshi Futakawa, Soichi Kojima, Yasuhiro Hashimoto, Jamey D. Marth, James C. Paulson, and Naoyuki Taniguchi
    • Organizer
      2009 Annual Meeting of the Society for Glycobiology
    • Place of Presentation
      san Diego
    • Year and Date
      2009-11-14
    • Data Source
      KAKENHI-PROJECT-21570154
  • [Presentation] Solubule smyloid precrsor protein 770 is secreted in a O-glycosylated form from inflamed endothelial cells

    • Author(s)
      Shinobu Kitazume, Akiomi Yoshihisa, Takayoshi Yamaki, Masayoshi Oikawa, Yuriko Tachida, Kazuko Ogawa, Rie Imamaki, Yoshiaki Hagiwara, Noriaki Kinoshita, Yasuchika Takeishi, Nobuhisa Iwata, Takaomi Saido, Naomasa Yamamoto and Naoyuki Taniguchi
    • Organizer
      Glyco22
    • Place of Presentation
      中国・大連
    • Invited
    • Data Source
      KAKENHI-PROJECT-25430122
  • [Presentation] 脱髄疾患の進行に関わる脳特異的な分岐型O-Man 糖鎖

    • Author(s)
      兼清健志、稲森 啓一郎、○北爪しのぶ、前田純、樋口真人、是金宏昭、松尾一郎、本家孝一、谷口直之
    • Organizer
      日本生化学会
    • Place of Presentation
      横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-25430122
  • [Presentation] Bisecting GlcNAc欠損によるアルツハイマー病抑制に関する研究

    • Author(s)
      木塚康彦、北爪しのぶ、藤縄玲子、斎藤貴志、岩田修永、西道隆臣、中の三弥子、山口芳樹、橋本康弘、Matthias Staufenbiel、初田裕幸、村山繁雄、萬谷博、遠藤玉夫、谷口直之
    • Organizer
      第33回日本糖質学会年会
    • Place of Presentation
      名古屋
    • Year and Date
      2014-08-10 – 2014-08-12
    • Data Source
      KAKENHI-PROJECT-26670148
  • [Presentation] High-throughput screening of GnT-III inhibitors using UDP-Glo system to develop a novel drug candidate for Alzheimer’s disease

    • Author(s)
      Yasuhiko Kizuka, Shinobu Kitazume, Keiko Sato, Tetsuo Ohnuki, Mutsuko Kukimoto-Niino, Mikako Shirouzu, Minoru Yoshida, Laurie Engel, Hicham Zegzouti, Naoyuki Taniguchi
    • Organizer
      SFG & JSCR 2014 Joint Annual Meeting
    • Place of Presentation
      Honolulu
    • Year and Date
      2014-11-16 – 2014-11-19
    • Data Source
      KAKENHI-PROJECT-26670148
  • 1.  橋本 康弘 (80164797)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 2.  辻 崇一 (90124677)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  新堂 晃大 (60422820)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  Kizuka Yasuhiko (20564743)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 11 results
  • 5.  TANIGUCHI Naoyuki (90002188)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 17 results
  • 6.  NAKANO Miyako (40397724)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 7.  NAKAJIMA Kazuki (10442998)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  高島 晶 (00300880)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  豊田 英尚 (70217579)
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  • 10.  小島 隆生 (50807469)
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  • 11.  石川 英洋 (00793499)
    # of Collaborated Projects: 1 results
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  • 12.  伊井 裕一郎 (40362347)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  藤井 正純 (10335036)
    # of Collaborated Projects: 1 results
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  • 14.  SATO Keiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 15.  OHTSUBO Kazuaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 16.  KOREKANE Hiroaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 17.  田中 克典
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  深瀬 浩一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  竹石 恭知
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  及川 雅啓
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  小椋 章弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  木曽 真
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  石田 秀治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  佐原 成彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  斉藤 貴志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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