OKADA TAROU 岡田太郎

… Alternative Names

岡田太郎オカダタロウ

OKADA Tarou 岡田太郎

Less

Researcher Number	80304088
Other IDs	https://orcid.org/0000-0001-5183-9402
Affiliation (Current)	2024: 神戸大学, 医学研究科, 准教授
Affiliation (based on the past Project Information) *help	2022: 神戸大学, 医学研究科, 准教授 2016 – 2020: 神戸大学, 医学研究科, 准教授 2014 – 2015: 神戸大学, 大学院医学研究科, 准教授 2012 – 2015: 神戸大学, 医学(系)研究科(研究院), 准教授 2011 – 2012: 神戸大学, 大学院・医学研究科, 准教授 … More 2008 – 2011: 神戸大学, 医学研究科, 准教授 2008: 神戸大学, 大学院・医学研究科, 准教授 2007: Kobe University, Graduate School of Medicine, Associate Professor 2006: 神戸大学, 医学系研究科, 助教授 2005: 神戸大学, 大学院医学系研究科, 助教授 2002 – 2004: 神戸大学, 大学院・医学系研究科, 講師 2001: 神戸大学, 大学院・医学系研究科, 助手 1998 – 2000: 神戸大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 44010:Cell biology-related / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / General medical chemistry / Functional biochemistry Except Principal Investigator Respiratory organ internal medicine / General medical chemistry / Pathological medical chemistry / Biological Sciences / Basic Section 49010:Pathological biochemistry-related … More / Medium-sized Section 48:Biomedical structure and function and related fields / Pathological medical chemistry / General medical chemistry / Functional biochemistry Less
Keywords	Principal Investigator スフィンゴ脂質 / パーキンソン病 / スフィンゴシン１リン酸 / スフィンゴシン１－リン酸 / スフィンゴシンキナーゼ / S1P / α－シヌクレイン / エクソソーム / スフィンゴシン1-リン酸 / シグナル伝達 … More / シヌクレイノパチー / αシヌクレイン / 神経変性疾患 / パルミトイル化 / スフィンゴシン１－リン酸受容体 / ガングリオシド / スフィンゴシン１リン酸受容体 / S1P受容体 / 神経伝達物質放出 / スフィンゴシン1リン酸 … More Except Principal Investigator スフィンゴシンキナーゼ / スフィンゴシン1リン酸 / 細胞内情報伝達 / S1P / エキソソーム / S1P受容体 / スフィンゴシン・キナーゼ / コリン燐脂質 / ADP-リボシル化因子 / G_<M2>アクチベーター / ホスホリパーゼD / パーキンソン病 / 気管支喘息 / 神経伝達物質 / グルタミン酸 / 海馬 / エンドソーム / マクロピノサイトーシス / ホスホイノシタイド / レビー小体 / αシヌクレイン / スフィンゴシン１燐酸 / 後期エンドソーム / LBPA / リゾビスフォスファチジン酸 / スフィンゴシン１リン酸 / bronchial asthma / lung fibroblast / sphingosine kinase / sphingosine 1-phosphate / 急性喘息モデル / 線維芽細胞 / ADP-ribosvlation factor / G-protein / G_<M2> activator / Phospholipase D / Signal transduction / 癌微細環境 / Met / 治療 / 気道リモデリング / 気道炎症 / 国際情報交換 / マウス / 卵白アルブミン / 樹状細胞 / IL-33 / IL-25 / TSLP / JTE013 / 喘息 / スフィンゴシン1リン酸受容体 / スフィンゴシン1燐酸(SIP) / GABA / 分子病態学 / goblet cells / IL-13 / ERK / mucin / Shingosine kinase / SlP受容体 / Sphingosine kinase / 粘液産生 / スフィンゴシン / 苔状線維 / 自発放出 / 核移行シグナル / 核排出シグナル / 生理活性 / 生体分子 / 脂質 / 酵素 / シグナル伝達 / イノシトール燐脂質 / スフィンゴシン1燐酸 / スフィンゴ脂質 / 小胞輸送 / 酵母ツーハイブリッド法 / PXドメイン / RPK118 / 初期エンドソーム / ADP―リボシル化因子 / ホスファチジルイノシトール4,5二リン酸 / ホスファチジルコリン / プロテイン・キナーゼC / ADPリボシル化因子 Less

シヌクレイノパチーにおける細胞外αシヌクレインによる新規病変伝播機構の解明Principal Investigator
- Principal Investigator
  
  岡田太郎
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Kobe University
Involvement of S1P receptor signaling and exosome release on Parkinson's diseasePrincipal Investigator
- Principal Investigator
  
  Okada Taro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Kobe University
Analysis on pathogenesis of Parkinson's disease through S1P signaling
- Principal Investigator
  
  Nakamura Shun-ichi
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  Kobe University
Analysis of molecular mechanism underlying S1P signal-mediated exosome release
- Principal Investigator
  
  Nakamura Shun-ichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kobe University
Inhibition of S1P receptor signal transduction by extracellular alpha-synucleinPrincipal Investigator
- Principal Investigator
  
  OKADA TARO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kobe University
Studies on the coupling mechanism between lysobisphosphatidic acid (LBPA) and S1P signaling
- Principal Investigator
  
  Nakamura Shun-ichi
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Kobe University
Regulation of cancer malignancy through the cargo sorting into exosomes
- Principal Investigator
  
  NAKAMURA Shun-ichi
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kobe University
S1P receptors on neuronal cells as a target of medicine for epilepsyPrincipal Investigator
- Principal Investigator
  
  OKADA Taro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kobe University
Role of sphingolipids in the respiratory immune system
- Principal Investigator
  
  NISHIMURA Yoshihiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kobe University
Mechanism underlying the regulation of brain function through sphingosine kinase/S1P signaling
- Principal Investigator
  
  NAKAMURA Shunichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kobe University
The role of sphingosine kinases on the formation of neural network in dentate granule cells of hippocampusPrincipal Investigator
- Principal Investigator
  
  OKADA Taro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kobe University
The control of airway mucus secretion via sphingosine signals
- Principal Investigator
  
  NISHIMURA Yoshihiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kobe University
スフィンゴ脂質による神経伝達物質放出機構の解析
- Principal Investigator
  
  中村俊一
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
Studies on the mechanism of nucleo/cytoplasmic shuttling of sphingosine kinase
- Principal Investigator
  
  NAKAMURA Shunichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kobe University
Research of sphingosine kinase modification in acute lung injury
- Principal Investigator
  
  NISHIMURA Yoshihiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kobe University
スフィンゴシン1リン酸に結合する核内受容体の同定Principal Investigator
- Principal Investigator
  
  岡田太郎
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kobe University
エンドソーム形成の分子メカニズムの解析
- Principal Investigator
  
  中村俊一
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Kobe University
低分子G蛋白質ARF依存性ホスホリパーゼDの活性化機構の解析
- Principal Investigator
  
  NAKAMURA Shunichi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (B)
- Review Section
  
  Biological Sciences
- Research Institution
  Kobe University
Studies on the mechanism of activation of phospholipase D
- Principal Investigator
  
  NAKAMURA Shun-ichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kobe University
G_<M2>アクチベーターによるホスホリパーゼDの活性化機構に関する研究
- Principal Investigator
  
  中村俊一
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Functional biochemistry
- Research Institution
  Kobe University

[Book] 細胞工学2015
- Author(s)
  梶本武利、岡田太郎、中村俊一
- Total Pages
  5
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-24590112
[Book] 細胞内外で機能するスフィンゴシン1リン酸(S1P)の役割2012
- Author(s)
  岡田太郎、中村俊一
- Publisher
  生化学
- Data Source
  KAKENHI-PROJECT-21590309
[Journal Article] Identification of novel OCRL isoforms associated with phenotypic differences between Dent disease-2 and Lowe syndrome2021
- Author(s)
  Sakakibara Nana、Ijuin Takeshi、Horinouchi Tomoko
- Journal Title
  
  Nephrology Dialysis Transplantation
  
  Volume: 37 Issue: 2 Pages: 262-270
- DOI
  10.1093/ndt/gfab274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15864, KAKENHI-PROJECT-22K06206
[Journal Article] Involvement of Receptor-Mediated S1P Signaling in EGF-Induced Macropinocytosis in COS7 Cells2020
- Author(s)
  Shubi Ambwene Matovelo, Lifang Zhang, Nesma Nabil Ibrahim Mohamed, Taketoshi Kajimoto, Takeshi Ijuin, Taro Okada, Shun-Ichi Nakamura
- Journal Title
  
  Kobe J Med Sci
  
  Volume: 66
- NAID
  120006975791
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06657
[Journal Article] Involvement of receptor-mediated S1P signaling in EGF-induced macropinocytosis in COS7 cells2020
- Author(s)
  Matovelo Shubi Ambwene, Zhang Lifang, Mohamed Nesma Nabil Ibrahim, Kajimoto Taketoshi, Ijuin Takeshi, Okada Taro, Nakamura Shun-ichi
- Journal Title
  
  Kobe J Med Sci.
  
  Volume: 66
- NAID
  120006975791
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02623
[Journal Article] Activation of atypical protein kinase C by sphingosine 1-phosphate revealed by an aPKC-specific activity reporter2019
- Author(s)
  Kajimoto Taketoshi、Caliman Alisha D.、Tobias Irene S.、Okada Taro、Pilo Caila A.、Van An-Angela N.、Andrew McCammon J.、Nakamura Shun-ichi、Newton Alexandra C.
- Journal Title
  
  Science Signaling
  
  Volume: 12 Issue: 562
- DOI
  10.1126/scisignal.aat6662
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08594, KAKENHI-PROJECT-15KK0307, KAKENHI-PROJECT-18K06657, KAKENHI-PROJECT-18H02623, KAKENHI-PROJECT-18K19430
[Journal Article] Extracellular α-synuclein drives sphingosine 1-phosphate receptor subtype 1 out of lipid rafts, leading to impaired inhibitory G protein signaling.2018
- Author(s)
  Badawy SMM, Okada T, Kajimoto T, Hirase M, Matovelo SA, Nakamura S, Yoshida D, Ijuin T, Nakamura SI.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: in press Issue: 21 Pages: 8208-8216
- DOI
  10.1074/jbc.ra118.001986
- NAID
  120006554634
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08585, KAKENHI-PROJECT-15K07930, KAKENHI-PROJECT-17K08594, KAKENHI-PROJECT-18K06657, KAKENHI-PROJECT-18K19430, KAKENHI-PROJECT-18H02623
[Journal Article] Involvement of Gβγ subunits of Gi protein coupled with S1P receptor on multivesicular endosomes in F-actin formation and cargo sorting into exosomes2018
- Author(s)
  Kajimoto, T., Mohamed, N.N.I., Badawy, S.M.M., Matovelo, S.A., Hirase, M., Nakamura, S., Yoshida, D., Okada, T., Ijuin, T., Nakamura, S.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 293 Issue: 1 Pages: 245-253
- DOI
  10.1074/jbc.m117.808733
- NAID
  120006554633
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08594, KAKENHI-PROJECT-15K07930
[Journal Article] Essential Role of Sphingosine Kinase 2 in the Regulation of Cargo Contents in the Exosomes from K562 Cells2018
- Author(s)
  Mohamed Nesma Nabil Ibrahim, Okada Taro, Kajimoto Taketoshi, Nakamura Shun-ichi
- Journal Title
  
  Kobe J Med Sci.
  
  Volume: 25;63(4)
- NAID
  120006471054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02623
[Journal Article] DHHC5-mediated palmitoylation of S1P receptor subtype 1 determines G-protein coupling2017
- Author(s)
  Badawy SMM, Okada T, Kajimoto T, Ijuin T, Nakamura SI.
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 16552-16552
- DOI
  10.1038/s41598-017-16457-4
- NAID
  120006380402
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08585, KAKENHI-PROJECT-17K08594, KAKENHI-PROJECT-15K07930
[Journal Article] Extracellular α-synuclein induces sphingosine 1-phosphate receptor subtype 1 uncoupled from inhibitory G-protein leaving β-arrestin signal intact.2017
- Author(s)
  Zhang L, Okada T, Badawy SM, Hirai C, Kajimoto T, Nakamura SI.
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 44248-44248
- DOI
  10.1038/srep44248
- NAID
  120006380401
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460341, KAKENHI-PROJECT-15K07930
[Journal Article] Impairment of PDGF-induced chemotaxis by extracellular α-synuclein through selective inhibition of Rac1 activation2016
- Author(s)
  Okada, T., Hirai, C., Badawy, S., Zhang, L., Kajimoto, T., Nakamura, SI.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 37810-37810
- DOI
  10.1038/srep37810
- NAID
  120005898707
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460341, KAKENHI-PROJECT-15K07930
[Journal Article] High expression of Mcl-1L via the MEK-ERK-phospho-STAT3 (Ser727) pathway protects melanocytes and melanoma from UVB-induced apoptosis.2016
- Author(s)
  Fukumoto-T, Iwasaki-T, Okada-T, Hashimoto-T, Moon-Y, Sakaguchi-M, Fukami-Y, Nishigori-C, Oka-M.
- Journal Title
  
  Genes Cells.
  
  Volume: 21 Issue: 2 Pages: 185-199
- DOI
  10.1111/gtc.12330
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07930, KAKENHI-PROJECT-15K19689, KAKENHI-PROJECT-26461692
[Journal Article] エキソソームの形成機構2015
- Author(s)
  梶本武利、岡田太郎、中村俊一
- Journal Title
  
  細胞工学
  
  Volume: ３４ Pages: 168-173
- Data Source
  KAKENHI-PROJECT-15K15066
[Journal Article] エキソソームの形成機構2015
- Author(s)
  梶本武利、岡田太郎、中村俊一
- Journal Title
  
  細胞工学
  
  Volume: 34 Pages: 168-173
- Data Source
  KAKENHI-PROJECT-26670158
[Journal Article] Sphingosine kinases modulate the secretion of amyloid β precursor protein from SH-SY5Y neuroblastoma cells: the role of α-synuclein2014
- Author(s)
  Jesko, H., Okada, T., Strosznajder, R. P., & Nakamura, S.
- Journal Title
  
  Folia Neuropathol.
  
  Volume: 52 Pages: 70-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670158
[Journal Article] Sphingosine kinases modulate the secretion of amyloid β precursor protein from SH-SY5Y neuroblastoma cells: the role of α-synuclein.2014
- Author(s)
  Jesko H, Okada T, Strosznajder RP, Nakamura S.
- Journal Title
  
  Folia Neuropathol
  
  Volume: 52 Pages: 70-78
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590112
[Journal Article] Ongoing activation of sphingosine 1-phosphate receptors mediates maturation of exosomal multivesicular endosomes.2013
- Author(s)
  Taketoshi Kajimoto, Taro Okada, Satoshi Miya, Lifang Zhang, Shun-ichi Nakamura
- Journal Title
  
  Nature Communications
  
  Volume: 4:2712 Issue: 1 Pages: 1-13
- DOI
  10.1038/ncomms3712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790293, KAKENHI-PROJECT-24590112
[Journal Article] 細胞内外で機能するスフィンゴシン1リン酸(S1P)の役割2012
- Author(s)
  岡田太郎、中村俊一
- Journal Title
  
  生化学
  
  Volume: 84 Pages: 92-101
- NAID
  10030346307
- Data Source
  KAKENHI-PROJECT-22390053
[Journal Article] Regulation of synaptic strength by sphingosine 1-phosphate in the hippocampus2010
- Author(s)
  Kanno T, Nishizaki T, Proia RL, Kajimoto T, Jahangeer S, Okada T, Nakamura S
- Journal Title
  
  Neuroscience
  
  Volume: 29 Pages: 973-80
- Data Source
  KAKENHI-PROJECT-21590309
[Journal Article] Sphingosine kinase 1 regulates mucin production via ERK phosphorylation2010
- Author(s)
  Kono Y, Nishiuma T, Okada T, Kobayashi K, Funada Y, Kotani Y, Jahangeer S, Nakamura S, Nishimura Y
- Journal Title
  
  Pulm Pharmacol Ther
  
  Volume: 23(1) Pages: 36-42
- NAID
  120003290046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590965
[Journal Article] Sphingosine kinase 1 regulates mucin production via ERK phosphorylation2010
- Author(s)
  Kono Y, Nishiuma T, Okada T, Kobayashi K, Funada Y, Kotani Y, Jahangeer S, Nakamura S, Nishimura Y
- Journal Title
  
  Pulm Pharmacol Ther
  
  Volume: 23 Pages: 36-42
- NAID
  120003290046
- Data Source
  KAKENHI-PROJECT-21590309
[Journal Article] Regulation of synaptic strength by sphingosine 1-phosphate in the hippocampus.2010
- Author(s)
  Kanno, T., Nishizaki, T., Proia, R. L., Kajimoto, T., Jahangeer, S., Okada, T., & Nakamura, S.
- Journal Title
  
  Neurosci
  
  Volume: 171 Pages: 973-980
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390053
[Journal Article] Sphingosine kinase 1 regulates mucin production via ERK phosphorylation2010
- Author(s)
  Kono, Y., Nishiuma, T., Okada, T., Kobayashi, K., Funada, Y., Kotari, Y., Jahangeer, S., Nakamura S., Nishimura Y.
- Journal Title
  
  Pulm.Pharmacol.Ther.
  
  Volume: 23 Pages: 36-42
- NAID
  120003290046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390053
[Journal Article] Regulation of synaptic strength by sphingosine 1-phosphate in the hippocampus2010
- Author(s)
  Kanno, T., Nishizaki, T., Proia, L., Kajimoto, T., Jahangeer, S., Okada., T., Nakamura, S
- Journal Title
  
  Neuroscience
  
  Volume: 171 Pages: 7-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390053
[Journal Article] Sphingosine kinase 1 regulates mucin production via ERK phosphorylation2010
- Author(s)
  Kono, Y., Nishiuma, T., Okada, T., Kobayashi, K., Funada, Y., Kotani, Y., Jahangeer, S., Nakamura, S., Nishimura, Y.
- Journal Title
  
  Pulm.Pharmacol.Ther. 23
  
  Pages: 36-42
- NAID
  120003290046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20022026
[Journal Article] Sphingosine kinase/sphingosine 1-phosphate signalling in central nervous system2009
- Author(s)
  Okada, T., Kajimoto, T., Jahangeer, S., Nakamura, S.
- Journal Title
  
  Cell. Signal 21
  
  Pages: 7-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590309
[Journal Article] Sphingosine kinase/sphingosine 1-phosphate signalling in central nervous system2009
- Author(s)
  Okada T, Kajimoto T, Jahangeer S, Nakamura S
- Journal Title
  
  Cell Signal
  
  Volume: 21 Pages: 7-13
- Data Source
  KAKENHI-PROJECT-21590309
[Journal Article] Roles of extracellular and intracellular sphingosine 1-phosphate in cell migration2009
- Author(s)
  Yu H, Okada T, Kobayashi M, Abo-Elmatty DM, Jahangeer S, Nakamura S
- Journal Title
  
  Genes Cells
  
  Volume: 14 Pages: 597-605
- Data Source
  KAKENHI-PROJECT-21590309
[Journal Article] CtBP1/BARS is an activator of phospholipase D1 necessary for agonist-induced macropinocytosis2009
- Author(s)
  Haga, Y., Miwa, N., Jahangeer, S., Okada, T., Nakamura, S.
- Journal Title
  
  EMBO J. 28
  
  Pages: 1197-1207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20022026
[Journal Article] Roles of extracellular and intracellular sphingosine 1-phosphate in cell migration2009
- Author(s)
  Yu, H., Okada, T., Kobayashi, M., Abo-Elmatty, D.M., Jahangeer, S., Nakamura, S.
- Journal Title
  
  Genes Cells 14
  
  Pages: 597-605
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20022026
[Journal Article] Sphingosine kinase/sphingosine 1-phosphate signalling in central nervous system2009
- Author(s)
  Okada, T., Kajimoto, T., Jahangeer, S., & Nakamura, S.
- Journal Title
  
  Cell. Signal. 21
  
  Pages: 7-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20022026
[Journal Article] CtBP1/BARS is an activator of phospholipase D1 necessary for agonist-induced macropinocytosis2009
- Author(s)
  Haga Y, Miwa N, Jahangeer S, Okada T, Nakamura S
- Journal Title
  
  EMBO J
  
  Volume: 28 Pages: 1197-207
- Data Source
  KAKENHI-PROJECT-21590309
[Journal Article] Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model2008
- Author(s)
  Nishiuma, T, Nishimura, Y, Okada, T, Kuramoto, E, Kotani, Y, Jahangeer, S, Nakamura, S
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590848
[Journal Article] Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model2008
- Author(s)
  Nishiuma, T., Nishimura, Y., Okada, T., Kuramoto, E., Kotani, Y., Jahangeer, S., & Nakamura, S.
- Journal Title
  
  Am. J. Physiol. Lung Cell. Mo1. Physiol. 294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590309
[Journal Article] Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model2008
- Author(s)
  Nishiuma, T., Nishimura, Y., Okada, T., Kuramoto, E., Kotani, Y., Jahangeer, S., Nakamura, S.
- Journal Title
  
  Am. J. Physiol. Lung Cell. Mol. Physiol. 294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590309
[Journal Article] Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model.2008
- Author(s)
  Nishiuma T, Nishimura Y, Okada T, Kuramoto E, Kotani Y, Jahangeer S, Nakamura S
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol (In press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590848
[Journal Article] Inhalation of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model2008
- Author(s)
  Nishiuma, T., Nishimura, Y., Okada, T., Kuramoto, E., Kotani, Y., Jahan geer, S., & Nakamura, S.
- Journal Title
  
  Am. J. Physiol. Lung Cell. Mol. Physiol. 294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20022026
[Journal Article] Involvement of sphingosine-1-phosphate in glutamate secretion in hippocampal neurons2007
- Author(s)
  Kajimoto, T., Okada, T., Yu, F., Goparaju, S. K., Jahangeer, S., Nakamura. S.
- Journal Title
  
  Mol. Cell. Biol. 27
  
  Pages: 3429-3440
- NAID
  10024355377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590309
[Journal Article] Involvement of sphingosine-1-phosphate in glutamate secretion in hippocampal neurons2007
- Author(s)
  Kajimoto, T., Okada, Y., Yu, H., Goparaju, S., Jahangeer, S. & Nakamura, S.
- Journal Title
  
  Mol. Cell. Biol. 27
  
  Pages: 3429-3440
- NAID
  10024355377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590309
[Journal Article] Sphingosine kinase 1 regulates differentiation of human and mouse lung fibroblasts mediated by TGF{beta}12007
- Author(s)
  Kono, Y., Nishiuma, T., Nishimura, Y., Kotani, Y., Okada, T., Nakamura, S., Yokoyama M.
- Journal Title
  
  Am. J. Respir. Cell. Mol. Biol. 37
  
  Pages: 395-404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590309
[Journal Article] Requirement of phospholipase D for ilimaquinone-induced Golgi membrane fragmentation2007
- Author(s)
  Sonoda, H., Okada, T., Jahangeer, S., and Nakamura, S.
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 34085-34092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590309
[Journal Article] Sphingosine kinase 1 regulates differentiation of human and mouse lung fibroblasts mediated by TGF-beta12007
- Author(s)
  Kono, Y, Nishiuma, T, Nishimura, Y, Kotani, Y, Okada, T, Nakamura, S, Yokoyama, M
- Journal Title
  
  Am J Respir Cell Mol Biol 37
  
  Pages: 395-404
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590848
[Journal Article] Requirement of phospholipase D for ilimaquinone-induced Golgi membrane fragmentation2007
- Author(s)
  Sonoda, H., Okada, T., Jahangeer, S., Nakamura, S.
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 34085-34092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590309
[Journal Article] Sphingosine kinase 1 regulates differentiation of human and mouse lung fibroblasts mediated by TGF-beta12007
- Author(s)
  Kono Y, Nishiuma T, Nishimura Y, Kotani Y, Okada T, Nakamura S, Yokoyama M.
- Journal Title
  
  Am J Respir Cell Mol Biol 37
  
  Pages: 395-404
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590848
[Journal Article] Protein kinase D-mediated phosphorylation and nuclear export of sphingosine kinase 22007
- Author(s)
  Ding, G., Sonoda, H., Yu, H., Kajimoto, T., Goparaju, S. K., Jahangeer, S., Okada, T., Nakamura, S.
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 27493-27502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590309
[Journal Article] Protein kinase D-mediated phosphorylation and nuclear export of sphingosine kinase 22007
- Author(s)
  Ding G, Sonoda H, Yu H, Kajimoto T, Goparaju SK, Jahangeer S, Okada T, Nakamura S.
- Journal Title
  
  J. Biol. Chem. 282
  
  Pages: 27493-27502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590309
[Journal Article] Involvement of N-terminal-extended form of sphingosine kinase 2 in Serum-dependent regulation of cell proliferation and apoptosis2005
- Author(s)
  岡田太郎
- Journal Title
  
  The Journal of Biological Chemistry 280
  
  Pages: 36318-36325
- Data Source
  KAKENHI-PROJECT-16770098
[Presentation] 細胞外α-シヌクレインによるスフィンゴシン-1-リン酸受容体の阻害とその影響2022
- Author(s)
  岡田太郎
- Organizer
  第15回セラミド研究会・第１６回スフィンゴテラピィ研究会合同学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K06206
[Presentation] Regulation of multivesicular body maturation by S1P signaling2013
- Author(s)
  Nakamura, S., Kajimoto, T., Miya, S., Zhang, L., and Okada, T.
- Organizer
  8th Sphingo-therapy conference
- Place of Presentation
  Yamanakaonsen-Kajikaso Royal Hotel
- Invited
- Data Source
  KAKENHI-PROJECT-24590112
[Presentation] Sphingolipid signaling and neuronal function2011
- Author(s)
  Nakamura, S., Fukai, E., Miya, S., Jesko, H., & Okada, T.
- Organizer
  52nd International Conference onthe Bioscience of Lipids
- Place of Presentation
  Warsaw, Poland
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PROJECT-22390053
[Presentation] Sphingolipid signaling and neuronal function2011
- Author(s)
  Nakamura, S., Fukai, E., Miya, S., Jesko, H., Okada, T.
- Organizer
  52^<nd> International Conference on the Bioscience of Lipids
- Place of Presentation
  ワルシャワ(ポーランド)(招待講演)
- Year and Date
  2011-08-03
- Data Source
  KAKENHI-PROJECT-22390053
[Presentation] Nakamura, S., Fukai, E., Jesko, H., & Okada, T.2010
- Author(s)
  Nakamura, S., Fukai, E., Jesko, H., & Okada, T.
- Organizer
  第83回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22390053
[Presentation] スフィンゴシン1リン酸による神経伝達物質放出の調節2009
- Author(s)
  中村俊一、岡田太郎
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-20022026
[Presentation] Sphingosine 1-phosphate in physiology and pathology in the brain2009
- Author(s)
  Nakamura, S. and Okada, T.
- Organizer
  9th International Congress of the Polish Neuroscience Society in Warsow
- Place of Presentation
  Poland
- Data Source
  KAKENHI-PROJECT-21590309
[Presentation] スフィンゴシンキナーゼ2によるエキソソーム放出の調節2008
- Author(s)
  中村俊一、岡田太郎
- Organizer
  第3回スフィンゴテラピィ(STC)研究会
- Place of Presentation
  大山(鳥取)
- Year and Date
  2008-04-18
- Data Source
  KAKENHI-PROJECT-20022026
[Presentation] スフィンゴシンキナーゼ2によるエキソソーム放出の調節2008
- Author(s)
  中村俊一, 岡田太郎
- Organizer
  第3回スフィンゴテラピイ(STC)研究会
- Place of Presentation
  鳥取
- Data Source
  KAKENHI-PROJECT-19590309
[Presentation] スフィンゴシンキナーゼ2によるエキソソーム放出の調節2008
- Author(s)
  中村俊一, 岡田太郎
- Organizer
  第3回スフィンゴテラピィ(STC)研究会
- Place of Presentation
  大山(鳥取)
- Year and Date
  2008-07-18
- Data Source
  KAKENHI-PROJECT-19590309
[Presentation] Sphingosine Kinase(SPHK)1 Regulates Differentiation of Lung Fibroblasts Mediated by Transforming Growth Factor (TGF) beta12007
- Author(s)
  Kono Y, Nishiuma T, Nishimura Y, Okada T, Kobayashi K, Funada Y, Kotani Y, Nakamura S, Yokoyama M
- Organizer
  米国胸部疾患学会(American Thoracic Society)
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2007-05-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590848
[Presentation] Effect of sphingosine kinase on IL-13 induced goblet cell metaplasia2007
- Author(s)
  Kono, Y, Nishiuma, T, Nishimura, Y, Okada, T, Kobayashi, K, Funada, Y, Kotani, Y, Nakamura, S, Yokoyama, M
- Organizer
  Asian Pacific Society of Respirology
- Place of Presentation
  Gold Coast, Australia
- Year and Date
  2007-12-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590848
[Presentation] Sphingosine Kinase(SPHK)1 Regulates Differentiation of Lung Fibroblasts Mediated by Transforming Growth Factor(TGF)betal2007
- Author(s)
  Kono, Y, Nishiuma, T, Nishimura, Y, Okada, T, Kobayashi, K, Funada, Y, Kotani, Y, Nakamura, S, Yokoyama, M
- Organizer
  American Thoracic Society
- Place of Presentation
  San Francisco, CA, USA
- Year and Date
  2007-05-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590848
[Presentation] Ongoing activation of sphingosine 1-phosphate receptors mediates maturation of exosomal multivesicular endosomes
- Author(s)
  梶本武利、岡田太郎、宮聡志、張麗芳、中村俊一
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26670158

1. NAKAMURA Shunichi (40155833)

# of Collaborated Projects: 11 results

# of Collaborated Products: 32 results
2. MIWA Noriko (50202354)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. KAJIMOTO Taketoshi (00509953)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
4. NISHIMURA Yoshihiro (20291453)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
5. JAHANGEER Saleem (80314475)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
6. KOTANI Yoshikazu (90403287)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
7. KOBAYASHI Kazuyuki (50403275)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. NISHIUMA Teruaki (10379414)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
9. 伊集院壮 (00361626)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
10. FUNADA Yasuhiro (60437465)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. HIRATA Kenichi (20283880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 榊原菜々

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

OKADA TAROU 岡田 太郎

岡田 太郎 オカダ タロウ

OKADA Tarou 岡田 太郎

Research Projects

Research Products

Co-Researchers

シヌクレイノパチーにおける細胞外αシヌクレインによる新規病変伝播機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Involvement of S1P receptor signaling and exosome release on Parkinson's diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Inhibition of S1P receptor signal transduction by extracellular alpha-synucleinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

S1P receptors on neuronal cells as a target of medicine for epilepsyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of sphingosine kinases on the formation of neural network in dentate granule cells of hippocampusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

OKADA TAROU 岡田太郎

岡田太郎オカダタロウ

OKADA Tarou 岡田太郎