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OHBAYASHI Takehisa  大林 武久

ORCIDConnect your ORCID iD *help
Researcher Number 80304997
Affiliation (based on the past Project Information) *help 2012: 熊本大学, 医学部附属病院, 非勤診療医師
2010 – 2012: 熊本大学, 医学部附属病院, 非常勤診療医師
2003 – 2004: 熊本大学, 医学部附属病院, 助手
1998 – 2001: 熊本大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Periodontal dentistry
Except Principal Investigator
Surgical dentistry / Surgical dentistry
Keywords
Principal Investigator
RI標識 / 予防および治療法開発 / プロテオミクス / RI 標識 / 白血球細胞表面タンパク / ジンジパイン / システインプロテアーゼ / Porphyromonas gingivalis / 成人型歯周病
Except Principal Investigator
TIMP … More / MMP / 口腔扁平上皮癌 / Metastasis / Invasion / Squamous cell carcinoma / CGH / personalized medicine / drug resistance / genetic diagnosis / drug delivery / antitumor agent / drug response / CGH法 / 個別化治療 / 薬剤感受性 / ゲノム遺伝子解析 / 抗癌剤耐性遺伝子 / 個別治療 / 遺伝子診断 / 遺伝子マーカー / CGH分析 / 抗癌剤耐性 / 遺伝子導入 / MMP阻害剤 / 浸潤 / 転移 / 浸潤、転移 / 扁平上皮癌 Less
  • Research Projects

    (4 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (5 People)
  •  Analysis of gingipains target molecule of the white corpuscle cell surface by radioactivity mark and proteomics.Principal Investigator

    • Principal Investigator
      OHBAYASHI Takehisa
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Kumamoto University
  •  Genome research on interindividual variations on drug response and application of genetic diagnosis to personalized medicine

    • Principal Investigator
      SHINOHARA Masanori
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Kumamoto University
  •  Study of roles of matrix metalloproteinase (MMP) and tissue inhibitor of MMP (TIMP) in metastastic mechanisms of oral squamous cell carcinoma (OSCC) cell line.

    • Principal Investigator
      SHINOHARA Masanori
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Kumamoto University
  •  Study of degradation mechanism of extracellular matrix in oral cancer and possible development of matrix metalloproteinase inhibitors as anticancer drugs

    • Principal Investigator
      SHINOHARA Masanori
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Surgical dentistry
    • Research Institution
      Kumamoto University

All 2012 2011

All Journal Article Presentation

  • [Journal Article] Degradation of fibrinogen and collagen by staphopains, cysteine proteases released from Staphylococcus aureus.2011

    • Author(s)
      Takehisa Ohbayashi
    • Journal Title

      Microbiology

      Volume: 157 Pages: 786-792

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592316
  • [Journal Article] Degradation of fibrinogen and collagen by staphopains2011

    • Author(s)
      Takehisa Ohbayashi, Atsushi Irie,Yoji Murakami, Magdalena Nowak,Jan Potempa, Yasuharu Nishimura,Masanori Shinohara, and Takahisa Imamura
    • Journal Title

      cysteine proteasesreleased from Staphylococcus aureusMicrobiology

      Volume: 157巻 Pages: 786-792

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22592316
  • [Presentation] 黄色ブドウ球菌プロテアーゼ・スタホパインのフィブリノゲンとコラーゲン分解作用2012

    • Author(s)
      大林 武久、今村 隆寿、篠原 正徳
    • Organizer
      第57回日本口腔外科学会総会学術大会
    • Place of Presentation
      横浜(パシフィコ横浜会議センター)
    • Data Source
      KAKENHI-PROJECT-22592316
  • [Presentation] 黄色ブドウ球菌プロテアーゼ・スタホパインのフィブリノゲンとコラーゲン分解作用2012

    • Author(s)
      大林 武久、今村 隆寿、篠原 正徳
    • Organizer
      第57回日本口腔外科学会総会学術大会
    • Place of Presentation
      パシフィコ横浜会議センター(神奈川)
    • Year and Date
      2012-10-19
    • Data Source
      KAKENHI-PROJECT-22592316
  • [Presentation] 黄色ブドウ球菌システインプロテアーゼの凝固系および結合織破壊作用の研究 -フィブリノゲンとコラーゲン分解作用解析-2011

    • Author(s)
      大林 武久、今村 隆寿、入江 厚、村上 洋嗣、篠原 正徳
    • Organizer
      第65回日本口腔科学会総会
    • Place of Presentation
      タワーホール船堀(東京)
    • Year and Date
      2011-04-22
    • Data Source
      KAKENHI-PROJECT-22592316
  • [Presentation] Degradation of Fibrinogen andCollagen by Staphopains: Implicationsin Impair -ed Plasma Clotting andTissue Destruc -tion Caused byStaphylo-coccus aureus Infection2011

    • Author(s)
      Takehisa Ohbayashi, Atsushi Irie,Yoji Murakami, Jan Potempa,Masanori Shinohara,Takahisa Imamura
    • Organizer
      Seventh General Meeting of theInternational Proteolysis Society
    • Place of Presentation
      Hilton San Diego Resortand Spa , San Diego , CA, USA
    • Year and Date
      2011-10-17
    • Data Source
      KAKENHI-PROJECT-22592316
  • [Presentation] Degradation of Fibrinogen and Collagen by Staphopains : Implications in Impaired Plasma Clotting and Tissue Destruction Caused by Staphylo-coccus aureus Infection2011

    • Author(s)
      Takehisa Ohbayashi
    • Organizer
      Seventh General Meeting of the International Proteolysis Society
    • Place of Presentation
      Hilton San Diego Resort and Spa, San Diego, CA, USA
    • Year and Date
      2011-10-17
    • Data Source
      KAKENHI-PROJECT-22592316
  • [Presentation] 黄色ブドウ球菌システインプロテアーゼの凝固系および結合織破壊作用の研究-フィブリノゲンとコラーゲン分解作用解析-2011

    • Author(s)
      大林武久
    • Organizer
      日本口腔科学会総会
    • Place of Presentation
      タワーホール船堀、東京
    • Year and Date
      2011-04-22
    • Data Source
      KAKENHI-PROJECT-22592316
  • [Presentation] 黄色ブドウ球菌病原因子 staphopainsの病原作用解析 -フィブリノゲンおよびコラーゲン分解作用2011

    • Author(s)
      今村 隆寿、大林 武久、村上 洋嗣
    • Organizer
      第100回日本病理学会総会
    • Place of Presentation
      パシフィコ横浜会議センター(神奈川)
    • Year and Date
      2011-04-28
    • Data Source
      KAKENHI-PROJECT-22592316
  • 1.  SHINOHARA Masanori (90117127)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 5 results
  • 2.  IKEBE Tetsuro (20202913)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  IMAMURA Takahisa (20176499)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 4.  IRIE Atusi (30250343)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 5.  NAKAMURA Seiji (60189040)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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