Yamochi Tadanori 矢持忠徳

… Alternative Names

YAMOCHI Tadanori 矢持忠徳

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Researcher Number	80306844
Other IDs
Affiliation (Current)	2025: 昭和大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2012 – 2016: 東京大学, 新領域創成科学研究科, 特任研究員 2009: 東京大学, 医科学研究所, 産学官連携研究員 2005 – 2007: 東京大学, 医科学研究所, 産学官連携研究員 1999 – 2001: 慶應義塾大学, 医学部, 助手
Review Section/Research Field	Principal Investigator 膠原病・アレルギー・感染症内科学 / Hematology / 内科学一般 / Neurology Except Principal Investigator Biological Sciences / Neurology / Hematology / 膠原病・アレルギー・感染症内科学 / Psychiatric science
Keywords	Principal Investigator Sjogren's syndrome / Ro52 / Autoimmune Disease / Sjogren'S syndrome / 自己免疫疾患 / 成人T細胞性白血病 / 癌幹細胞 / Cancer stem cell / Adult T cell Leukemia / ATL … More / Tumor initiating cells / Cancer stem cells / Adult T cell leukemia / p53 / リン酸化 / 細胞周期 / ik3-1 / cdk3 / αシヌクレイン / 細胞死 / アルツハイマー病 … More Except Principal Investigator RAP / LRP / TGF-β / Cas-L / β1インテグリン / ApoE4 / 神経細胞死 / Apolipoprotein E3 / α2-macroglobullin / Neuronal Death / Apolipoprotein E4 / 細胞死抑制 / ApoE3 / α2マクログロブリン / ゲノム機能発現 / 血液腫瘍学 / 接着分子 / Smad / Lipid raft / Efs / p130^<Cas> / ERK / 細胞遊走 / SHP-2 / Nck / IRAK-1 / Tollip / Caveolin-1 / CARMA-1 / 共刺激リガンド / CD86 / メモリーT細胞 / エフェクターT細胞 / TIA-1陽性T細胞 / CD26陽性T細胞 / 異種GVHDマウス / ヒト化CD26抗体 / DPPIV酵素 / caveolin.1 / CD28 / Xeno-GVHD / CD8T細胞 / 自己免疫疾患 / DPPIV / 共刺激分子 / caveolin-1 / CD26 / 臨床免疫学 / リウマチ学 / 膠原病 / 癌転移 / 癌浸潤 / Smad7 / Smad6 / ドッキング蛋白 / αサブユニット Less

Integrated analysis of abnormal expression profiles that define phenotype of ATL cells
- Principal Investigator
  
  Watanabe Toshiki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  St. Marianna University School of Medicine
  The University of Tokyo
Analyzing the mechanisms underlying ATL leukemogenesis and identifying new markers of ATL stem cell using ATL humanized micePrincipal Investigator
- Principal Investigator
  
  YAMOCHI Tadanori
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
癌浸潤・転移におけるβ1インテグリン及び関連分子の役割の解明と臨床応用の探索
- Principal Investigator
  
  森本幾夫
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Analysis of the Ro52's function and structure and biological significance of autoimmune diseasePrincipal Investigator
- Principal Investigator
  
  YAMOCHI Tadanori
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The University of Tokyo
β1インテグリン及び下流ドッキング蛋白Cas-Lのがん浸潤、転移での役割
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Basic Approach for the Development of Molecular Target Therapy for Autoimmune Diseases and Immune-Mediated Disorders.
- Principal Investigator
  
  MORIMOTO Chikao
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The University of Tokyo
G1サイクリン基質の同定と機能解析-cdk3に注目してPrincipal Investigator
- Principal Investigator
  
  矢持忠徳
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  内科学一般
- Research Institution
  Keio University
神経細胞におけるアミロイド前駆体蛋白とαシヌクレインの機能の解析Principal Investigator
- Principal Investigator
  
  矢持忠徳
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Keio University
ApoE4の誘導する神経細胞死機構の萌芽的研究
- Principal Investigator
  
  松岡正明
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Psychiatric science
- Research Institution
  Keio University
Elucidation of the principal mechanism for dementia and identification of anti-dementia genes through the analysis of ApoE4 neurotoxicity
- Principal Investigator
  
  NISHIMOTO Ikuo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  Keio University

All 2016 2015 2014 2013 2012 2008 2007 2006 2005

All Journal Article Presentation

[Journal Article] Transition of ATL/L cell clones can be observed during the clinical course2016
- Author(s)
  Aoki S, Firouzi S, Yamochi T, Nakan K, Uchimaru K, Utusnomiya A, Iwanaga M, Watanabe T
- Journal Title
  
  Int J Hematol
  
  Volume: 印刷中 Issue: 3 Pages: 330-337
- DOI
  10.1007/s12185-016-2049-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293226, KAKENHI-PROJECT-16H05248, KAKENHI-PROJECT-15F15385
[Journal Article] Polycomb-dependent epigenetic landscape in adult T-cell leukemia.2016
- Author(s)
  Dai Fujikawa; Shota Nakagawa; Makoto Hori; Naoya Kurokawa; Ai Soejima; Kazumi Nakano; Tadanori Yamochi; Makoto Nakashima; Seiichiro Kobayashi; Yuetsu Tanaka; Masako Iwanaga; Atae Utsunomiya; Kaoru Uchimaru; Makoto Yamagishi; Toshiki Watanabe
- Journal Title
  
  Blood
  
  Volume: 127 Issue: 14 Pages: 1790-1802
- DOI
  10.1182/blood-2015-08-662593
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J08236, KAKENHI-PROJECT-16H05248, KAKENHI-PROJECT-16H05323, KAKENHI-PROJECT-26293226, KAKENHI-PROJECT-15K06907, KAKENHI-PROJECT-16H06277
[Journal Article] Advanced HTLV-1 carriers and early-stage indolent ATLs are indistinguishable based on CADM1 positivity in flow cytometry2015
- Author(s)
  Kobayashi S, Watanabe E, Ishigaki T, Ohno N, Yuji K, Nakano K, Yamochi T, Watanabe N, Tojo A, Watanabe T, Uchimaru K.
- Journal Title
  
  Cancer Sci
  
  Volume: 印刷中 Issue: 5 Pages: 598-603
- DOI
  10.1111/cas.12639
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24501304, KAKENHI-PROJECT-24591383, KAKENHI-PROJECT-26293226, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-14J07244
[Journal Article] Identification of TL-Om1, an ATL Cell Line, as a Reference Material for Human T-Lymphotropic Virus 1 Quantitative PCR.2015
- Author(s)
  Kuramitsu M, Okuma K, Yamagishi M, Yamochi T, Firouzi S, Momose H, Mizukami T, Takizawa K, Araki K, Sugamura K, Yamaguchi K, Watanabe T, Hamaguchi I.
- Journal Title
  
  Journal of Clinical Microbiology
  
  Volume: 53 Issue: 2 Pages: 587-596
- DOI
  10.1128/jcm.02254-14
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-12J06916, KAKENHI-PROJECT-24570142, KAKENHI-PROJECT-24591383, KAKENHI-PROJECT-24591414, KAKENHI-PROJECT-25290047, KAKENHI-PROJECT-25860798, KAKENHI-PROJECT-26293226, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-15K06848, KAKENHI-PROJECT-25461440
[Journal Article] CADM1 expression and stepwise downregulation of CD7 are closely associated with 2 clonal expansion of HTLV-1-infected cells in adult T-cell leukemia/lymphoma2014
- Author(s)
  Seiichiro Kobayashi, Kazumi Nakano, Eri Watanabe, Tomohiro Ishigaki, Nobuhiro Ohno, Koichiro Yuji, Naoki Oyaizu, Satomi Asanuma, Makoto Yamagishi, Tadanori Yamochi, Nobukazu Watanabe, Arinobu Tojo, Toshiki Watanabe, Kaoru Uchimaru
- Journal Title
  
  Clinical Cancer Research
  
  Volume: In Press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591383
[Journal Article] Development and validation of a new high-throughput method to investigate the clonality of HTLV-1-infected cells based on provirus integration sites.2014
- Author(s)
  Firouzi S, Lopez Y, Suzuki Y, Nakai K, Sugano S, Yamochi T, Watanabe T.
- Journal Title
  
  Genome Medicine
  
  Volume: 6(6) Issue: 6 Pages: 46-46
- DOI
  10.1186/gm568
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-12J06916, KAKENHI-PROJECT-24591383, KAKENHI-PROJECT-26293226, KAKENHI-PROJECT-221S0001
[Journal Article] HTLV-1キャリアが産生するウイルス構造蛋白質に対する抗体と末梢血中のプロウイルス量に関する解析」、2014
- Author(s)
  井上由紀子，守田麻衣子，後藤信代，相良康子，入田和男，矢持忠徳，渡邉俊樹，岩永正子，浜口功，清川博之、
- Journal Title
  
  日本輸血細胞治療学会誌
  
  Volume: 60(6) Pages: 592-599
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591383
[Journal Article] CADM1 expression and stepwise downregulation of CD7 are closely associated with clonal expansion of HTLV-I-infected cells in adult T-cell leukemia/lymphoma2014
- Author(s)
  Kobayashi S, Nakano K, Watanabe E, Ishigaki T, Ohno N, Yuji K, Oyaizu N, Asanuma S, Yamagishi M, Yamochi T, Watanabe N, Tojo A, Watanabe T, Uchimaru K
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 20(11) Issue: 11 Pages: 2851-61
- DOI
  10.1158/1078-0432.ccr-13-3169
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-14J07244, KAKENHI-PROJECT-24501304, KAKENHI-PROJECT-24591383, KAKENHI-PROJECT-26293226, KAKENHI-PROJECT-221S0001
[Journal Article] Epigenetic deregulation of Ellis Van Creveld confers robust Hedgehog signaling in adult T-cell leukemia2014
- Author(s)
  Takahashi R; Yamagishi M, Nakano K, Yamochi T, Yamochi T, Fujikawa D, Nakashima M, Tanaka Y, Uchimaru K, Utsunomiya A, Watanabe T
- Journal Title
  
  Cancer Sci
  
  Volume: 105 Issue: 9 Pages: 1160-1169
- DOI
  10.1111/cas.12480
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24501304, KAKENHI-PROJECT-24591383, KAKENHI-PROJECT-26293226, KAKENHI-PROJECT-221S0001
[Journal Article] Adult T-cell leukemia cells are characterized by abnormalities of Helios expression that promote T-cell growth.2013
- Author(s)
  Asanuma S, Uchimaru K, et al.
- Journal Title
  
  Cancer Sci
  
  Volume: - Issue: 8 Pages: 1097-1106
- DOI
  10.1111/cas.12181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591028, KAKENHI-PROJECT-23390250, KAKENHI-PROJECT-23659484, KAKENHI-PROJECT-24591383, KAKENHI-PROJECT-24790436, KAKENHI-PROJECT-221S0001
[Journal Article] Adult T-cell leukemia cells are characterized by abnormalities of Helios expression that promotes T-cell growth.2013
- Author(s)
  Asanuma S, Yamagishi M, Kawanami K, Nakano K, Sato-Otsubo A, Muto S, Sanada M, Yamochi T, Kobayashi S, Utsunomiya A, Iwanaga M, Yamaguchi K, Uchimaru K, Ogawa S, Watanabe T.
- Journal Title
  
  Cancer Science
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591383
[Journal Article] HIV-1-encoded antisense RNA suppresses viral replication for a prolonged period.2012
- Author(s)
  Kobayashi-Ishihara M, Yamagishi M, Hara T, Matsuda Y, Takahashi R, Miyake A, Nakano K, Yamochi T, Ishida T, Watanabe T
- Journal Title
  
  Retrovirology
  
  Volume: 9 Issue: 1 Pages: 38-38
- DOI
  10.1186/1742-4690-9-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591383, KAKENHI-PROJECT-24790436
[Journal Article] SSA/Ro52 autoantigen interacts with Dcp2 to enhance its decapping activity2008
- Author(s)
  Yamochi T, Ohnuma K, Hosono O, Tanaka H, Kanai Y, Morimoto C.
- Journal Title
  
  Biochem Biophys Res Commun. 370
  
  Pages: 195-9
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Role of CD26/dipepridyl peptidase IV in human T cell activation and function2008
- Author(s)
  Ohmuma k, Takahashi N, Yamochi T, Hodono O, Dang NH, Morimoto C.
- Journal Title
  
  Fromt Biosci 13
  
  Pages: 2299-2310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Role of CD26/dipeptidyl peptidase IV in human T cell activation and function2008
- Author(s)
  Ohnuma K, Takahashi N, Yamochi T, Hosono O, Dang NH, Morimoto C.
- Journal Title
  
  Front Biosci. 13
  
  Pages: 2299-310
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Caveolin-1 triggers T-cell activation via CD26 in association with CARMA12007
- Author(s)
  Ohnuma K, Uchiyama M, Yamochi T, Nishibashi K, Hosono O, Takahashi N, Kina S, Tanaka H, Lin X, Dang NH, Morimoto C.
- Journal Title
  
  J Biol Chem. 282
  
  Pages: 10117-31
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Humanized Anti-CD26 monoclonal antibody as a treatment for malignant mesothelioma tumors2007
- Author(s)
  Inamoto T, Yamada T, Ohnuma K, Kina S, Takahashi N, Yamochi T, Inamoto S, Katsuoka Y, Hosono O, Tanaka H, Dang NH, Morimoto C.
- Journal Title
  
  Clin Cancer Res. 13
  
  Pages: 4191-200
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Anti-CD26 monoclonal antibody-mediated G1-S arrest of human renal clear cell carcinoma Caki-2 is associated with retinoblastoma substrate dephosphorylation, cyclin-dependent kinase 2 reduction, p27 (kipl) enhancement, and disruption of binding to the extracellular matrix2006
- Author(s)
  Inamoto T, Yamochi T, Ohnuma K, Iwata S, Kina S, Inamoto S, Tachibana M, Katsuoka Y, Dang NH, Morimoto C.
- Journal Title
  
  Clin Cancer Res. 12
  
  Pages: 3470-7
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] CD26 mediates dissociation of Tollip and IRAK-1 from caveolin-1 and induces upregulation of CD86 on antigen-presenting cells2005
- Author(s)
  Ohnuma K, Yamochi T, Uchiyama M, Nishibashi K, Iwata S, Hosono O, Kawasaki H, Tanaka H, Dang NH, Morimoto C.
- Journal Title
  
  Mol Cell Biol. 25
  
  Pages: 7743-57
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] CD26 T cells in the pathogenesis of asthma.2005
- Author(s)
  Ohnuma K, Yamochi T, Hosono O, Morimoto C.
- Journal Title
  
  Clin Exp Immunol. 139
  
  Pages: 13-16
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] CD26 regulates p38 mitogen-activated protein kinase-dependent phosphorylation of integrin betal, adhesion to extracellular matrix, and tumorigenicity of T-anaplastic large cell lymphoma Karpas 2992005
- Author(s)
  Sato T, Yamochi T, Yamochi T, Aytac, Ohnuma K, McKee KS, Morimoto C, Dang NH.
- Journal Title
  
  Cancer Res. 65
  
  Pages: 6950-6
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Regulation of p38 phosphorylation and topoisomerase llalpha expression in the B-cell lymphoma line Jiyoye by CD26/dipeptidyl peptidase IV is associated with enhanced in vitro and in vivo sensitivity to doxorubicin.2005
- Author(s)
  Yamochi T, Morimoto C, et al.
- Journal Title
  
  Cancer Res. 65
  
  Pages: 1973-1983
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] CD26 T cells in the pathogenesis of asthma2005
- Author(s)
  Ohnuma K, Yamochi T, Hosono O, Morimoto C.
- Journal Title
  
  Clin Exp Immunol. 139
  
  Pages: 13-16
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Regulation of p38 phosphorylation and topoisomerase IIalpha expression in the B-cell lymphoma line Jiyoye by CD26/dipeptidyl peptidase IV is associated with enhanced in vitro and in vivo sensitivity to doxorubicin2005
- Author(s)
  Yamochi T, Yamochi T, Aytac U, Sato T, Sato K, Ohnuma K, McKee KS, Morimoto C, Dang NH.
- Journal Title
  
  Cancer Res. 65
  
  Pages: 1973-83
- Data Source
  KAKENHI-PROJECT-17109011
[Journal Article] Regulation of p38 phosphorylation and topoisomerase llalpha expression the B-cell lymphoma line Jiyoye by CD26/dipeptidyl peptidase IV is associated with enhanced in vitro and in vivo sensitivity to doxorubicin.2005
- Author(s)
  Yamochi T, Morimoto C, et al.
- Journal Title
  
  Cancer Res. 65
  
  Pages: 1973-1983
- Data Source
  KAKENHI-PROJECT-17014028
[Presentation] The emergence of hyperploid cells in CD30+ subpopulation of adult T-cell leukemia2016
- Author(s)
  中島誠、矢持忠徳、渡邊真理子、宇都宮與、東原正明、内丸薫、渡邉俊樹、堀江良一
- Organizer
  第78回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26293226
[Presentation] Polycomb-dependent epigenetic landscape in adult T cell leukemia (ATL); providing proof of concept for targeting EZH1/2 to selectively eliminate the HTLV-1 infected population2016
- Author(s)
  Yamagishi M, Fujikawa D, Ohsugi T, Honma D, Adachi N, Nakagawa S, Hori M, Kurokawa N, Soejima A, Nakano K, Yamochi T, Nakashima M, Kobayashi S, Tanaka Y, Iwanaga M, Utsunomiya A, Uchimaru K, Tsukasaki K, Araki K, Watanabe T
- Organizer
  T-cell Lymphoma Forum 2016
- Place of Presentation
  San Francisco, CA, U.S.A.
- Year and Date
  2016-01-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293226
[Presentation] 成人T細胞白血病におけるCD30陽性細胞集団に高倍数体細胞は出現する2016
- Author(s)
  中島誠、矢持忠徳、渡邊真理子、内丸薫、宇都宮與、東原正明、渡邉俊樹、堀江良一
- Organizer
  第3回日本HTLV-1学会学術集会
- Place of Presentation
  鹿児島県市町村自治会館、鹿児島
- Year and Date
  2016-08-27
- Data Source
  KAKENHI-PROJECT-26293226
[Presentation] Polycomb-Dependent Epigenetic Landscape in Adult T Cell Leukemia (ATL); Providing Proof of Concept for Targeting EZH1/2 to Selectively Eliminate the HTLV-1 Infected Population2015
- Author(s)
  Yamagishi M, Fujikawa D, Honma D, Adachi N, Nakagawa S, Hori M, Kurokawa N, Soejima A, Nakano K, Yamochi T, Nakashima M, Kobayashi S, Tanaka Y, Iwanaga M, Utsunomiya A, Uchimaru K, Tsukasaki K, Araki K, Watanabe T
- Organizer
  the 57th ASH Annual Meeting and Exposition
- Place of Presentation
  Orlando, FL, U.S.A.
- Year and Date
  2015-12-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293226
[Presentation] Tumor-specific gene expression leads to p38 and Hedgehog signaling activation in adult T cell leukemia2014
- Author(s)
  Yamagishi M, Takahashi R, Sakai N, Fujikawa D, Nakagawa S, Yamochi T, Yamochi T, Nakano K, Uchimaru K, Utsunomiya A, Watanabe T
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-11-01
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] A new high-throughput method to investigate the clonality of HTLV-1-infected cells based on provirus integration sites2014
- Author(s)
  Sanaz Firouzi, Tadanori Yamochi, Yosvany López, Yutaka Suzuki, Kenta Nakai, Sumio Sugano, Toshiki Watanabe
- Organizer
  第1回日本HTLV-1学会
- Place of Presentation
  東京大学医科学研究所
- Year and Date
  2014-08-23
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] CD30 expressing cells in HTLV-1 carriers reveal abnormal nuclear morphology resembling flower cells2014
- Author(s)
  Nakashima M, Yamochi T, Higashihara M, Watanabe T, Horie R
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場、大阪
- Year and Date
  2014-11-01
- Data Source
  KAKENHI-PROJECT-26293226
[Presentation] Monitoring clonal composition of HTLV-1-infected cells based on provirus integration sites2014
- Author(s)
  Firouzi S, Yamochi T, Lopez O, Suzuki Y, Nakai K, Sugano S, Watanabe T, ”Monitoring clonal composition of HTLV-1-infected cells based on provirus integration sites
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、横浜、
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] Tumor-specific gene expression leads to p38 and Hedgehog signaling activation in adult T cell leukemia2014
- Author(s)
  Yamagishi M, Takahashi R, Sakai N, Fujikawa D, Nakagawa S, Yamochi T, Yamochi T, Nakano K, Uchimaru K, Utsunomiya A, Watanabe T
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場、大阪
- Year and Date
  2014-11-01
- Data Source
  KAKENHI-PROJECT-26293226
[Presentation] Putative ATL tumor initiating cellsの解析2014
- Author(s)
  矢持忠徳、守田陽平、矢持淑子、Sanaz Firouzi、佐々木陽介、渡辺信和、内丸薫、宇都宮與、渡邉俊樹
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] HTLV-1 PVLと HLA Class I結合peptideの乖離時間との関連」、第62回日本ウイルス学会学術総会2014
- Author(s)
  相良康子、井上由紀子、守田麻衣子、後藤信代、岩永正子、矢持忠徳、渡邉俊樹、浜口功、相良康弘、清川博之、
- Organizer
  第62回日本ウイルス学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] Monitoring clonal composition of HTLV-1-infected cells based on provirus integration sites2014
- Author(s)
  Firouzi S, Yamochi T, Lopez O, Suzuki Y, Nakai K, Sugano S, Watanabe T
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-26293226
[Presentation] CD30 expressing cells in HTLV-1 carriers reveal abnormal nuclear morphology resembling flower cells2014
- Author(s)
  Nakashima M, Yamochi T, Higashihara M, Watanabe T, Horie R,
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-11-01
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] CD30はHTLV-1キャリアにおける異常リンパ球に発現し、核の形態変化に関与する2014
- Author(s)
  中島誠、矢持忠徳、東原正明、渡邉俊樹、堀江良一
- Organizer
  第1回日本HTLV-1学会
- Place of Presentation
  東京大学医科学研究所
- Year and Date
  2014-08-23
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] 単鎖抗体(scFv)を用いたHTLV-1感染細胞特異的miRNA輸送システムの構築2014
- Author(s)
  西田亜季、長門石曉、中野和民、山岸誠、矢持忠徳、田中勇悦、津本浩平、渡邉俊樹
- Organizer
  第1回日本HTLV-1学会学術集会
- Place of Presentation
  東京大学医科学研究所
- Year and Date
  2014-08-23
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] A new high-throughput method to investigate the clonality of HTLV-1-infected cells based on provirus integration sites2014
- Author(s)
  Sanaz Firouzi, Tadanori Yamochi, Yosvany Lopez, Yutaka Suzuki, Kenta Nakai, Sumio Sugano, Toshiki Watanabe
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] 成人T細胞白血病／リンパ腫（ATLL）における、がん幹細胞ニッチの組織病理学的同定の試み2013
- Author(s)
  若林翼, 矢持忠徳, 矢持淑子, 佐々木陽介, Sanaz Firouzi, 滝本雅文, 渡邉俊樹
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] The CD7 vs CADM1 plot in FACS is useful for selecion of advanced HTLV-1 carriers2013
- Author(s)
  Kobayashi S, Watanabe E, Ishigaki T, Ohno N, Yuji K, Nakano K, Yamochi T, Watanabe T, Watanabe N, Tojo A, Uchimaru K,
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] HAS-Flow法を用いたHTLV-1キャリア／くすぶり型ATL境界の検討2013
- Author(s)
  小林誠一郎、渡辺恵理、石垣知寛、中野和民、矢持忠徳、山岸誠、浅沼里実、大野伸広、湯地晃一郎、渡辺信和、東條有伸、渡邉俊樹、内丸薫、
- Organizer
  第6回HTLV-1研究会・シンポジウム
- Place of Presentation
  東京大学医科学研究所
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] 成人T細胞白血病(ATL)における、がん幹細胞微小環境の組織病理学的同定の試み2013
- Author(s)
  若林翼、矢持忠徳、矢持淑子、佐々木陽介、Sanaz Firouzi、瀧本雅文、渡邉俊樹、
- Organizer
  第6回HTLV-1研究会・シンポジウム
- Place of Presentation
  東京大学医科学研究所
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] Development and validation of a new high-throughput method to investigate T-cell-clonality and integration site preference among HTLV-1-infected individuals2013
- Author(s)
  Sanaz Firouzi、矢持忠徳、Lopez Yosvany、鈴木穣、中井謙太、菅野純夫、渡邉俊樹、
- Organizer
  第6回HTLV-1研究会・シンポジウム
- Place of Presentation
  東京大学医科学研究所
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] Putative ATL tumor initiating cells の解析2013
- Author(s)
  矢持忠徳、守田陽平、矢持淑子、Sanaz Firoouozi、佐々木陽介、若林翼、渡辺信和、内丸薫、宇都宮與、渡邉俊樹、
- Organizer
  第72回日本癌学会学術総会、
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] ATLにおけるTumor initiating cell探索の試み2013
- Author(s)
  矢持忠徳、守田陽平、矢持淑子、Sanaz Firouzi、佐々木陽介、渡辺信和、内丸薫、宇都宮與、渡邉俊樹、
- Organizer
  第6回HTLV-1研究会・シンポジウム
- Place of Presentation
  東京大学医科学研究所
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] 免疫不全マウスに連続継代移植されたヒト腫瘍細胞の継代５代目における染色体解析2013
- Author(s)
  佐藤均、Sanaz Firouzi、渡邉俊樹、矢持忠徳、
- Organizer
  染色体学会第64回年会
- Place of Presentation
  富山大学五福キャンパス
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] Development of a new high-throughput method to investigate T-cell-clonality and integration site preference among HTLV-1 infected individuals2012
- Author(s)
  Firouzi Sanaz、青木桜、鈴木穣、矢持忠徳、中野和民、中井謙太、菅野純夫、渡邉俊樹、
- Organizer
  NGS現場の会・第二回研究会
- Place of Presentation
  ホテル阪急エキスポパーク
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] Development of a new high-throughput method to investigate T-cell-clonality and integration site preference among HTLV-1 infected individuals2012
- Author(s)
  Firouzi Sanaz、青木桜、鈴木穣、矢持忠徳、中野和民、中井謙太、菅野純夫、渡邉俊樹、
- Organizer
  平成24年度東京大学医科学研究所研究成果発表会
- Place of Presentation
  東京大学医科学研究所
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] Development of a New High-throughout Method to Investigage T-cell-clonality and Integration Site Preference among HTLV-1-infected Individuals”,2012
- Author(s)
  Firouzi S, Yamochi T, Lopez Y, Aoki S, Suzuki Y, Nakano K, Nakai K, Sugano S, Watanabe T,
- Organizer
  第35回日本分子生物学会年会、
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] 成人T細胞性白血病におけるTumor Initiating Cellの探索の試み2012
- Author(s)
  矢持忠徳、守田洋平、矢持淑子、佐々木陽介、渡辺信和、Sanaz Firouzi、内丸薫、宇都宮與、渡邉俊樹，
- Organizer
  東京大学医科学研究所
- Place of Presentation
  東京大学医科学研究所
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] 「成人性T細胞性白血病におけるがん幹細胞の同定への試み」2012
- Author(s)
  矢持忠徳、守田陽平、矢持淑子、サナズフィルジ、佐々木陽介、渡辺信和、内丸　薫、宇都宮與、渡邉俊樹、
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] HIV-1由来antisense RNAによるウイルス複製抑制メカニズムの解析2012
- Author(s)
  小林美栄、山岸誠、松田有加、中野和民、矢持忠徳、石田尚臣、渡邉俊樹、
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-24591383
[Presentation] HIV-1由来新規antisense RNA,ASP-Lはウイルスを制御する機能性RNAである」2012
- Author(s)
  小林(石原)美栄、山岸誠、松田有加、中野和民、矢持忠徳、石田尚臣、渡邉俊樹、
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24591383

1. NIIKURA Takako (10301491)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. MATSUDA Shuji (70296721)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. MATSUOKA Masaaki (70222297)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. MORIMOTO Chikao (30119028)

# of Collaborated Projects: 3 results

# of Collaborated Products: 13 results
5. IWATA Satoshi (00396871)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
6. NISHIMOTO Ikuo (80180652)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. HOSONO Osamu (50190210)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
8. OHNUMA Kei (10396872)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
9. KAWASAKI Hiroshi (80280957)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. IKEDA Teturo (10360489)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. WATANABE Nobukazu (10334278)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
12. Watanabe Toshiki (30182934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KOUYAMA Keisuke (30296553)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 山崎裕人 (80376623)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 内丸薫 (60251203)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
16. 中野和民 (60549591)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
17. 山岸誠 (90625261)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
18. 渡辺俊樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 10 results
19. FIROUZI Sanaz

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

Yamochi Tadanori 矢持 忠徳

YAMOCHI Tadanori 矢持 忠徳

Research Projects

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Co-Researchers

Integrated analysis of abnormal expression profiles that define phenotype of ATL cells

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Analyzing the mechanisms underlying ATL leukemogenesis and identifying new markers of ATL stem cell using ATL humanized micePrincipal Investigator

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癌浸潤・転移におけるβ1インテグリン及び関連分子の役割の解明と臨床応用の探索

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Analysis of the Ro52's function and structure and biological significance of autoimmune diseasePrincipal Investigator

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β1インテグリン及び下流ドッキング蛋白Cas-Lのがん浸潤、転移での役割

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Basic Approach for the Development of Molecular Target Therapy for Autoimmune Diseases and Immune-Mediated Disorders.

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G1サイクリン基質の同定と機能解析-cdk3に注目してPrincipal Investigator

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神経細胞におけるアミロイド前駆体蛋白とαシヌクレインの機能の解析Principal Investigator

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ApoE4の誘導する神経細胞死機構の萌芽的研究

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Elucidation of the principal mechanism for dementia and identification of anti-dementia genes through the analysis of ApoE4 neurotoxicity

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[Journal Article] Transition of ATL/L cell clones can be observed during the clinical course2016

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[Journal Article] Polycomb-dependent epigenetic landscape in adult T-cell leukemia.2016

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[Journal Article] Advanced HTLV-1 carriers and early-stage indolent ATLs are indistinguishable based on CADM1 positivity in flow cytometry2015

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Yamochi Tadanori 矢持忠徳

YAMOCHI Tadanori 矢持忠徳