FUKAMI Kei 深水圭

… Alternative Names

深水圭フカミケイ

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Researcher Number	80309781
Other IDs
Affiliation (Current)	2025: 久留米大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2025: 久留米大学, 医学部, 教授 2015 – 2023: 久留米大学, 医学部, 教授 2009 – 2014: Kurume University, 医学部, 准教授 2007 – 2008: Kurume University, 医学部, 講師 2002 – 2003: 久留米大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Kidney internal medicine / Basic Section 53040:Nephrology-related / Kidney internal medicine Except Principal Investigator Basic Section 53040:Nephrology-related / Basic Section 53020:Cardiology-related / General pharmacology
Keywords	Principal Investigator Diabetic Nephropathy / aptamer / 糖尿病性腎症 / IL-10 / Breg / AKI / 母体環境 / アプタマー / AGEs / RAGE … More / CKD / Re-perfusion injury / B cell / 組織修復 / IRI / reperfusion / IL10 / 腎臓病 / メタボリック症候群 / 脳腎連関 / SGLT2 / 糖尿病 / 高血圧症 / AGEs-RAGE / 蛋白尿 / アルブミン尿 / 酸化ストレス / 高血圧 / メタボリックシンドローム / アディポネクチン / 腎障害 / glycation / RPGN / diabetic nephropathy / podocyte / AGE / 尿蛋白 / 尿細管間質 / MMP-2 / 細胞外基質 / 半月体形成腎炎 / Th2バランス / Th1 / electroporation / 可溶性受容体 / IL-12 / 半月体系成腎炎 … More Except Principal Investigator RAGE / CKD予防 / 尿中アルブミン排泄 / 母子保健 / 3歳児健診 / 母体環境 / 3歳児 / ３歳児健診 / アルブミン尿 / 血管リモデリング / ナノ粒子 / RAGE-aptamer / 肺動脈性肺高血圧症 / 細胞増殖 / S100蛋白 / モノクロタリン誘発性肺高血圧症 / DNA-aptamer / S100A8/A9蛋白 / 肺動脈平滑筋細胞 / 血小板由来増殖因子 / 終末糖化産物受容体 / 肺高血圧症 / カルボキシメチルリジン / 鉱質コルチコイド受容体 / 核酸アプタマー / RAGE-DNAアプタマー / アルドステロン / RAGE-DNAアプタマ- / 慢性腎臓病 / RAGEアプタマー / ミネラロコルチコイド受容体 / 終末糖化産物 / 高血圧性腎障害 Less

免疫応答性Breg細胞輸注療法の確立とAKI-to-CKD進展に対する治療への応用Principal Investigator
- Principal Investigator
  
  深水圭
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kurume University
Breg-IL-10 system as a novel therapeutic target in AKI-to-CKDPrincipal Investigator
- Principal Investigator
  
  深水圭
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kurume University
Breg-IL-10 system as a novel therapeutic target for CKDPrincipal Investigator
- Principal Investigator
  
  FUKAMI KEI
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kurume University
Toward a Model District for CKD Prevention Starting with Maternal and Child Health
- Principal Investigator
  
  Kaida Yusuke
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Kurume University
Development of new treatments with RAGE-aptamer-incorporated nanoparticles for pulmonary arterial hypertension
- Principal Investigator
  
  Nakamura Kazufumi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Okayama University
The efficacy of RAGE-DNA aptamer for prevention of hypertensive nephropathy
- Principal Investigator
  
  Shibata Ryo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kurume University
The mechanism of brain-renal interaction on metabolic syndrome-role of AGEs-RAGE system-Principal Investigator
- Principal Investigator
  
  FUKAMI KEI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kurume University
Maternal exposure to high-fat and high-fructose diet evokes hypoadiponectinemia and kidney injury in rat offspring.Principal Investigator
- Principal Investigator
  
  Fukami Kei
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kurume University
Novel therapeutic approach against receptor for advanced glycation end products in patients with diabetic nephropathy or RPGN.Principal Investigator
- Principal Investigator
  
  FUKAMI Kei
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kurume University
Tubulointerstitial injury is exacerbated in streptozotocin-induced diabetic matrix metalloproteinase-2 knockout micePrincipal Investigator
- Principal Investigator
  
  FUKAMI Kei
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kurume University
可溶性IL-12受容体を用いた半月体形成糸球体腎炎に対する遺伝子治療の検討Principal Investigator
- Principal Investigator
  
  深水圭
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kurume University

[Book] Pharma Medica2020
- Author(s)
  田口顕正、深水　圭
- Total Pages
  6
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-19K08693
[Book] 臨床透析2020
- Author(s)
  深水　圭
- Total Pages
  6
- Publisher
  臨床医学出版
- Data Source
  KAKENHI-PROJECT-19K08693
[Book] 九州人工透析研究会誌2020
- Author(s)
  深水　圭
- Total Pages
  4
- Publisher
  -
- Data Source
  KAKENHI-PROJECT-19K08693
[Book] 九州人工透析研究会誌2020
- Author(s)
  坂口由美子、水落記子、角　昌久、川崎真由美、深水　圭
- Total Pages
  6
- Publisher
  -
- Data Source
  KAKENHI-PROJECT-19K08693
[Book] 臨床と研究2016
- Author(s)
  山田奈々、深水　圭
- Total Pages
  4
- Publisher
  大道学館
- Data Source
  KAKENHI-PROJECT-25461239
[Book] 血液透析患者におけるカルニチン欠乏と酸化ストレス-AGEs軽減作用への期待2014
- Author(s)
  深水　圭、奥田誠也
- Total Pages
  137
- Publisher
  医学図書出版株式会社
- Data Source
  KAKENHI-PROJECT-25461239
[Book] アログリプチンからリナグリプチンへの切り替え例での臨床的有用性についてー血液透析患者における検討―2013
- Author(s)
  深水　圭
- Total Pages
  5
- Publisher
  Ther. Res.
- Data Source
  KAKENHI-PROJECT-22590904
[Book] Chapter 1 AGEs化反応の基礎、AGEｓ受容体2012
- Author(s)
  深水　圭
- Total Pages
  9
- Publisher
  メディカルレビュー
- Data Source
  KAKENHI-PROJECT-22590904
[Book] AGEの腎症進展における役割と治療法開発への期待2012
- Author(s)
  深水　圭
- Total Pages
  5
- Publisher
  腎と透析
- Data Source
  KAKENHI-PROJECT-22590904
[Book] An Overview of Diabetic Nephropathy2012
- Author(s)
  深水　圭
- Total Pages
  9
- Publisher
  Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome
- Data Source
  KAKENHI-PROJECT-22590904
[Book] An Overview of Diabetic Nephropathy Nutritional and Therapeutic Interventions for Diabetes and Metabolic Syndrome2012
- Author(s)
  Kei Fukami, Sho-ichi Yamagishi
- Total Pages
  9
- Publisher
  ACADEMIC PRESS
- Data Source
  KAKENHI-PROJECT-22590904
[Book] 糖尿病性腎症のすべて；腎症の治療・管理・対策とそのエビデンス2012
- Author(s)
  深水　圭
- Total Pages
  8
- Publisher
  Visual糖尿病臨床のすべて　中山書店
- Data Source
  KAKENHI-PROJECT-22590904
[Book] 糖尿病患者の酸化ストレスマーカー・AGE/PEDF糖尿病と酸化ストレス2011
- Author(s)
  深水圭、山岸昌一、奥田誠也
- Total Pages
  5
- Publisher
  メディカルレビュー
- Data Source
  KAKENHI-PROJECT-22590904
[Book] 日本臨床腎臓症候群(下巻)糖尿病にみられる急性腎不全2011
- Author(s)
  深水圭、奥田誠也
- Total Pages
  4
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-22590904
[Book] 留米医学会雑誌終末糖化産物からみた慢性腎臓病(CKD)の病態解明と治療戦略2011
- Author(s)
  深水圭久
- Data Source
  KAKENHI-PROJECT-22590904
[Book] テルミサルタンのすぐれた降圧効果と高い忍容性2011
- Author(s)
  山岸昌一、戸次久敏、山本喜一郎、曽根正好、中田真詩、野原正敏、深水圭、奥田誠也血圧第18巻、第7号
- Data Source
  KAKENHI-PROJECT-22590904
[Book] エビデンスが不十分な年齢層への降圧目標と降圧薬選択のポイント2009
- Author(s)
  深水圭、山岸昌一、奥田誠也薬局
- Data Source
  KAKENHI-PROJECT-19590970
[Book] 糖尿病合併高血圧におけるRA系の関わりとテルミサルタンの降圧効果とその有用性2008
- Author(s)
  羽田勝計、山岸昌一、深水圭、Mark Cooper
- Publisher
  Pharma Medica
- Data Source
  KAKENHI-PROJECT-19590970
[Book] 糖尿病と酸化ストレス糖尿病患者の酸化ストレスマーカー
- Author(s)
  深水圭、山岸昌一、奥田誠也
- Publisher
  AGEs/PEDF(in press)
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Effect of tolvaptan on renal involvement in patients with autosomal dominant polycystic kidney disease according to different gene mutations.2021
- Author(s)
  Moriyama T, Nakayama Y, Soejima M, Yokota Y, Ota K, Ito S, Kodama G, Nakamura N, Kurokawa Y, Yano J, Ueda U, Takamiya Y, Kaida Y, Hazama T, Shibata R, Koda Y, Fukami K.
- Journal Title
  
  Clin Exp Nephrol.
  
  Volume: 25 Issue: 3 Pages: 251-260
- DOI
  10.1007/s10157-020-01988-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K10137, KAKENHI-PROJECT-19K08693, KAKENHI-PROJECT-20K10571
[Journal Article] Triple combination therapy with telmisartan, amlodipine, and hydrochlorothiazide ameliorates albuminuria in a normotensive rat remnant kidney model2021
- Author(s)
  Ito S, Nakayama Y, Kodama G, Ota K, Taguchi K, Yusuke Kaida1, Yamagishi S and Fukami K.
- Journal Title
  
  Renal Replacement Therapy 7:16, 2021
  
  Volume: 7 Pages: 16-16
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08693
[Journal Article] l ‐carnitine supplementation vs cycle ergometer exercise for physical activity and muscle status in hemodialysis patients: A randomized clinical trial2020
- Author(s)
  Yano Junko、Kaida Yusuke、Maeda Takashi、Hashida Ryuki、Tonan Tatsuyuki、Nagata Shuji、Hazama Takuma、Nakayama Yosuke、Ito Sakuya、Kurokawa Yuka、Otome Takaomi、Shibata Ryo、Tashiro Kyoko、Kakuma Tatsuyuki、Matsuse Hiroo、Fukami Kei
- Journal Title
  
  Therapeutic Apheresis and Dialysis
  
  Volume: - Issue: 3 Pages: 304-313
- DOI
  10.1111/1744-9987.13576
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08693
[Journal Article] Inhibitory effects of RAGE-aptamer on development of monocrotaline-induced pulmonary arterial hypertension in rats2020
- Author(s)
  Nakamura Kazufumi、Akagi Satoshi、Ejiri Kentaro、Yoshida Masashi、Miyoshi Toru、Sakaguchi Masakiyo、Amioka Naofumi、Suastika Luh Oliva Saraswati、Kondo Megumi、Nakayama Rie、Takaya Yoichi、Higashimoto Yuichiro、Fukami Kei、Matsubara Hiromi、Ito Hiroshi
- Journal Title
  
  Journal of Cardiology
  
  Volume: - Issue: 1 Pages: 12-16
- DOI
  10.1016/j.jjcc.2020.12.009
- NAID
  120007182876
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08693, KAKENHI-PROJECT-18K08037, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-20K08424, KAKENHI-PROJECT-21K08108
[Journal Article] Safety and efficacy of single-needle leukocyte apheresis (LCAP) for treatment of ulcerative colitis2020
- Author(s)
  Shindo Y, Mitsuyama K, Yamasaki H, Imai T, Yoshioka S, Kuwaki K, Yamauchi R, Yoshimura T, Araki T, Morita M, Tsuruta K, Yamasaki S, Fukami K, Torimura T
- Journal Title
  
  Therapeutic Apheresis and Dialysis
  
  Volume: 24 Issue: 5 Pages: 503-510
- DOI
  10.1111/1744-9987.13539
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08481, KAKENHI-PROJECT-19K08693
[Journal Article] A new diagnostic indication device of a biomarker growth differentiation factor 15 for mitochondrial diseases: From laboratory to automated inspection2020
- Author(s)
  Koga Yasutoshi、Povalko Nataliya、Inoue Eisuke、Ishii Akiko、Fujii Katsunori、Fujii Tatsuya、Murayama Kei、Mogami Yukiko、Hata Ikue、Ikawa Masamichi、Fukami Kei、Fukumoto Yoshihiro、Nomura Masatoshi、Ichikawa Kazuki、Yoshida Kaori
- Journal Title
  
  Journal of Inherited Metabolic Disease
  
  Volume: 44 Issue: 2 Pages: 358-366
- DOI
  10.1002/jimd.12317
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08693, KAKENHI-PROJECT-20K08921, KAKENHI-PROJECT-18K07892
[Journal Article] Effect of switching from cinacalcet to etelcalcetide on secondary hyperparathyroidism in patients undergoing hemodialysis: an ESCORT trial.2020
- Author(s)
  Kurokawa Y, Kaida Y, Hazama T, Nakayama Y, Otome T, Shibata R, Ito S, Kodama G, Nakamura N, Kambe T, Moriyama T, Nagata A, Minami A, Ando R, Wada Y, Sugiyama M, Usui M, Chiba M, Moriyama A, Ohara A, Miyazaki H, Kakuma T, Fukami K.
- Journal Title
  
  Renal Replacement Therapy 6:64, 2020
  
  Volume: 6 Pages: 64-64
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08693
[Journal Article] Single Needle Granulocyte and Monocyte Apheresis for Ulcerative Colitis: A Retrospective Safety Analysis2019
- Author(s)
  Imai T, Yamasaki H, Mitsuyama K, Yamaga O, Sugihara G, Kaida Y, Shibata R, Hazama T, Yoshioka S, Torimura T, Fukami K, Yamashita N.
- Journal Title
  
  The Kurume Medical Journal
  
  Volume: 66 Issue: 1 Pages: 1-7
- DOI
  10.2739/kurumemedj.MS661002
- NAID
  130007867225
- ISSN
  0023-5679, 1881-2090
- Year and Date
  2019-03-31
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08693
[Journal Article] Kinetics of Serum Carnitine Fractions in Patients with Chronic Kidney Disease Not on Dialysis2019
- Author(s)
  YANO JUNKO、ITO SAKUYA、KODAMA GOH、NAKAYAMA YOSUKE、KAIDA YUSUKE、YOKOTA YUNOSUKE、KINOSHITA YUKIE、TASHIRO KYOKO、FUKAMI KEI
- Journal Title
  
  The Kurume Medical Journal
  
  Volume: 66 Issue: 3 Pages: 153-160
- DOI
  10.2739/kurumemedj.MS663001
- NAID
  130008101716
- ISSN
  0023-5679, 1881-2090
- Year and Date
  2019-09-30
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08693
[Journal Article] Effectiveness of cryofiltration and mizoribine combination with oral steroid therapy in a patient with membranoproliferative glomerulonephritis due to essential cryoglobulinemia.2019
- Author(s)
  Kurokawa Y, Koike K, Kaida Y, Ito S, Chiba H, Urae K, Moriyama T, Nakamura N, Imai T, Shibata R, Hazama T, Wakasugi D, Okuda S, Fukami K
- Journal Title
  
  CEN Case Rep
  
  Volume: 8 Issue: 3 Pages: 205-211
- DOI
  10.1007/s13730-019-00394-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08693
[Journal Article] Uremic Toxin–Targeting as a Therapeutic Strategy for Preventing Cardiorenal Syndrome2019
- Author(s)
  Taguchi Kensei、Elias Bertha C.、Brooks Craig R.、Ueda Seiji、Fukami Kei
- Journal Title
  
  Circ J
  
  Volume: 84 Issue: 1 Pages: 2-8
- DOI
  10.1253/circj.CJ-19-0872
- NAID
  130007772709
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2019-12-25
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08251, KAKENHI-PROJECT-19K08693, KAKENHI-PROJECT-17K16106
[Journal Article] 特集動脈硬化とカルシウム～カルシウムパラドックスの謎に迫る～ Seminar CKD-MBDにおけるAGEs-RAGE系の役割ｖ2019
- Author(s)
  Fujisawa H, Nakayama Y, Ueda K, Fukami K
- Journal Title
  
  CLINICAL CALCIUM
  
  Volume: 29 Issue: 2 Pages: 193-198
- DOI
  10.20837/4201902193
- ISSN
  0917-5857
- Year and Date
  2019-02-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09637, KAKENHI-PROJECT-19K08693
[Journal Article] Effectiveness of immunosuppressive therapy for nephrotic syndrome in a patient with late-onset Fabry disease: a case report and literature review.2019
- Author(s)
  Fujisawa H, Nakayama Y, Nakao S, Yamamoto R, Kurokawa Y, Nakamura N, Nagata A, Tsukimura T, Togawa T, Sakuraba H, Fukami K.
- Journal Title
  
  BMC Nephrol
  
  Volume: 20 Issue: 1 Pages: 469-469
- DOI
  10.1186/s12882-019-1657-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08693, KAKENHI-PROJECT-18K15071
[Journal Article] Advanced glycation end products evoke inflammatory reactions in proximal tubular cells via autocrine production of dipeptidyl peptidase-42018
- Author(s)
  Kaifu Kumiko、Ueda Seiji、Nakamura Nobutaka、Matsui Takanori、Yamada-Obara Nana、Ando Ryotaro、Kaida Yusuke、Nakata Masami、Matsukuma-Toyonaga Maki、Higashimoto Yuichiro、Fukami Kei、Suzuki Yusuke、Okuda Seiya、Yamagishi Sho-ichi
- Journal Title
  
  Microvascular Research
  
  Volume: 120 Pages: 90-93
- DOI
  10.1016/j.mvr.2018.07.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08968, KAKENHI-PROJECT-18K08251, KAKENHI-PROJECT-16K07101, KAKENHI-PROJECT-16K07307, KAKENHI-PROJECT-16K09637
[Journal Article] Crucial role of rage in inappropriate increase of smooth muscle cells from patients with pulmonary arterial hypertension.2018
- Author(s)
  Nakamura K, Sakaguchi M, Matsubara H, Akagi S, Sarashina T, Ejiri K, Akazawa K, Kondo M, Nakagawa K, Yoshida M, Miyoshi T, Ogo T, Oto T, Toyooka S, Higashimoto Y, Fukami K, Ito H.
- Journal Title
  
  PLoS One
  
  Volume: 13 Issue: 9 Pages: 1-11
- DOI
  10.1371/journal.pone.0203046
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08037, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16K07307, KAKENHI-PROJECT-16K09637
[Journal Article] Decline in estimated glomerular filtration rate is associated with risk of end-stage renal disease in type 2 diabetes with macroalbuminuria: an observational study from JDNCS.2018
- Author(s)
  Shimizu M, Furuichi K, Toyama T, Funamoto T, Kitajima S, Hara A, Ogawa D, Koya D, Ikeda K, Koshino Y, Kurokawa Y, Abe H, Mori K, Nakayama M, Konishi Y, Samejima K, Matsui M, Yamauchi H, Gohda T, Fukami K et al
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 22 Issue: 2 Pages: 377-387
- DOI
  10.1007/s10157-017-1467-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09637, KAKENHI-PROJECT-17K08979, KAKENHI-PROJECT-16H05837, KAKENHI-PROJECT-16K15326, KAKENHI-PROJECT-16K09622, KAKENHI-PLANNED-17H06394
[Journal Article] L-carnitine supplementation improves self-rating depression scale scores in uremic male patients undergoing hemodialysis2017
- Author(s)
  Kyoko Tashiro, Yusuke Kaida, Sho-ichi Yamagishi, Hideharu Tanaka, Miyuki Yokoro, Junko Yano, Kazuko Sakai, Yuka Kurokawa, Kensei Taguchi, Yosuke Nakayama, Takahiro Inokuchi, Kei Fukami
- Journal Title
  
  Letters in Drug Design & Discovery
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K09637
[Journal Article] Compared effects of calcium and sodium polystyrene sulfonate on mineral and bone metabolism and volume overload in pre-dialysis patients with hyperkalemia2017
- Author(s)
  Yosuke Nakayama, Kaoru Ueda, Sho-ichi Yamagishi, Miki Sugiyama, Chika Yoshida, Yuka Kurokawa, Nao Nakamura, Tomofumi Moriyama, Goh Kodama, Tomohisa Minezaki, Sakuya Ito, Akiko Nagata, Kensei Taguchi, Junko Yano, Yusuke Kaida, Kazutaka Shibatomi, Kei Fukami
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: 印刷中 Issue: 1 Pages: 35-44
- DOI
  10.1007/s10157-017-1412-y
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K09637
[Journal Article] RAGE-aptamer Blocks the Development and Progression of Experimental Diabetic Nephropathy.2017
- Author(s)
  Matsui, T., Higashimoto, Y., Nishino, Y., Nakamura, N., Fukami, K., Yamagishi, S.
- Journal Title
  
  Diabetes
  
  Volume: 66 Issue: 1 Pages: 1683-1695
- DOI
  10.1038/s41598-018-21176-5
- NAID
  40021434304
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07307, KAKENHI-PROJECT-16K08564, KAKENHI-PROJECT-16K19502, KAKENHI-PROJECT-16K09637, KAKENHI-PROJECT-18H02823, KAKENHI-PROJECT-17K19653
[Journal Article] RAGE-aptamer inhibits the growth and liver metastasis of melanoma in nude mice.2017
- Author(s)
  Nakamura, N., Matsui, T., Ishibashi, Y., Sotokawauchi, A., Fukami, K., Higashimoto, Y., Yamagishi, S.
- Journal Title
  
  Mol. Med.
  
  Volume: 23 Issue: 1 Pages: 295-306
- DOI
  10.2119/molmed.2017.00099
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07307, KAKENHI-PROJECT-16K09637
[Journal Article] Accurate estimation of protein/creatinine ratio on urine sample in CKD patients2016
- Author(s)
  Taguchi K, Ueda S, Fukami K
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: in press Issue: 3 Pages: 319-321
- DOI
  10.1007/s10157-016-1229-0
- Data Source
  KAKENHI-PROJECT-25461239
[Journal Article] Regulation of platelet count by erythropoiesis-stimulating agents-iron axis in hemodialysis patients2016
- Author(s)
  Kiyomi Koike, Kei Fukami, Atsushi Kawaguchi, Kazumasa Shimamatsu, Sho-ichi Yamagishi and Seiya Okuda
- Journal Title
  
  Int J Nephrol Renovasc Dis
  
  Volume: 31 Pages: 73-80
- DOI
  10.2147/ijnrd.s98196
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461239
[Journal Article] Maternal exposure to high-fat and high-fructose diet evokes hypoadiponectinemia and kidney injury in rat offspring2016
- Author(s)
  Nana Obara-Yamada, Sho-ichi Yamagishi, Yusuke Kaida, Miyuki Yokoro, Kensei Taguchi, Yosuke Nakayama, Ryotaro Ando, Katsuhiko Asanuma, Takanori Matsui, Seiji Ueda, Seiya Okuda, and Kei Fukami
- Journal Title
  
  Clinical and Experimental Nephrology
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461239
[Journal Article] Involvement of iron-evoked oxidative stress in smoking-related endothelial dysfunction in healthy young men.2014
- Author(s)
  Fukami K, Yamagishi S, Iida S, Matsuoka H, Okuda S
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 2 Pages: e89433-e89433
- DOI
  10.1371/journal.pone.0089433
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461239
[Journal Article] Dialysate VEGF is an independent determinant of serum albumin levels and predicts future withdrawal from peritoneal dialysis in uremic patients.2014
- Author(s)
  Hazama T, Fukami K, Yamagishi S, Kusumoto T, Sakai K, Adachi T, Sonoda K, Kasuga S, Ueda S, Okuda S
- Journal Title
  
  THER APHER DIAL
  
  Volume: 18 Issue: 5 Pages: 391-397
- DOI
  10.1111/1744-9987.12120
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461239
[Journal Article] Effects of switching from oral administration to intravenous injection of L-carnitine on lipid metabolism in hemodialysis patients2014
- Author(s)
  Fukami K, Yamagishi S, Sakai K, Nasu M, Okuda S
- Journal Title
  
  Clin Kidney J
  
  Volume: 7 Issue: 5 Pages: 470-474
- DOI
  10.1093/ckj/sfu082
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461239, KAKENHI-PROJECT-26860487
[Journal Article] Asymmetric dimethylarginine accumulates in the kidney during ischemia/reperfusion injury.2014
- Author(s)
  Nakayama Y, Ueda S, et al.
- Journal Title
  
  Kidney Int
  
  Volume: 85 Issue: 3 Pages: 570-578
- DOI
  10.1038/ki.2013.398
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23591210, KAKENHI-PROJECT-25461239
[Journal Article] Carnitine deficiency is associated with late-onset hypogonadism and depression in uremic men with hemodialysis2014
- Author(s)
  Fukami K, Yamagishi S, Sakai K, Kaida Y, Obayashi A, Nakayama Y, Ando R, Obara N, Ueda S, Wada Y, Okuda S
- Journal Title
  
  AGING MALE
  
  Volume: 17 Issue: 4 Pages: 238-242
- DOI
  10.3109/13685538.2014.888053
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461239
[Journal Article] AGEs-RAGE system in cardiovasculardisease.2013
- Author(s)
  Fukami K, Yamagishi S, Okuda S.
- Journal Title
  
  Cur Pharm Des
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904
[Journal Article] Effects of Switching from Calcium Carbonate to Lanthanum Carbonate on Bone Mineral Metabolism in Hemodialysis Patients.2013
- Author(s)
  Manabe R, Fukami K, Ando R, Sakai K, Kusumoto T, Hazama H, Adachi T, Kaida K, Nakayama N, Ueda S, Kohno K, Wada Y, Yamagishi S, Okuda S.
- Journal Title
  
  Ther Apher Dial. 17Suppl
  
  Volume: 1 Pages: 35-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904
[Journal Article] Evidence for a positive association between serum carnitine and free testosterone levels in uremic men with hemodialysis.2013
- Author(s)
  Sakai K, Fukami K, Yamagishi S, Kaida Y, Adachi T, Ando R, Manabe R, Otsuka A, Sugi K, Ueda S and Okuda S.
- Journal Title
  
  Rejevenation Res.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904
[Journal Article] Telmisartan inhibits AGE-induced podocyte damage and detachment.2013
- Author(s)
  Fukami K,Yamagishi S, Kaifu K, Matsui T, Kaida Y, Ueda S, Takeuchi M, Asanuma K, Okuda S.
- Journal Title
  
  Microvasc Res.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904
[Journal Article] Serum asymmetric dimethylarginine levels are independently associated with procollagen III N-terminal peptide in non-alcoholic fatty liver disease patients.2013
- Author(s)
  Hyogo H, Yamagishi S, Maeda S, Fukami K, Ueda S, Okuda S, Nakahara T, Kimura Y, Ishitobi T, Kazuki C.
- Journal Title
  
  Clin Exp Med.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904
[Journal Article] PEDF inhibits AGE-induced podocyte apoptosis via PPAR-gamma activation.2013
- Author(s)
  Ishibashi Y, Matsui T, Ohta K, Tanoue R, Takeuchi M, Asanuma K, Fukami K, Okuda S, Nakamura K, Yamagishi S.
- Journal Title
  
  Microvasc Res
  
  Volume: (85) Pages: 54-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904
[Journal Article] Glucagon-like Peptide-1 Receptor Agonist Inhibits Asymmetric Dimethylarginine Generation in the Kidney of Streptozotocin-Induced Diabetic Rats by Blocking Advanced Glycation End Product-Induced Protein Arginine Methyltranferase-1 Expression.2013
- Author(s)
  Ojima A, Ishibashi Y, Matsui T, Maeda S, Nishino Y, Takeuchi M, Fukami K, Yamagishi SI. Am J Pathol.
- Journal Title
  
  Am J Pathol.
  
  Volume: 182(1) Pages: 132-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904
[Journal Article] DNA aptamer raised against AGEs blocks the progression of experimental diabetic nephropathy.2013
- Author(s)
  Kaida Y, Fukami K, Matsui T, Higashimoto Y, Nishino Y, Obara N, Nakayama Y, Ando R, Toyonaga M, Ueda S, Takeuchi M, Inoue, H, Okuda S, Yamagishi
- Journal Title
  
  Diabetes(S. Kaida Y and Fukami K contributed equally to this study)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904
[Journal Article] First reported case of collagenofibrotic glomerulopathy with a full-house pattern of immune deposits.2013
- Author(s)
  Fukami K, Yamagishi S, Minezaki TNishi S, Hisano S, Okuda S.
- Journal Title
  
  Clin Nephrol.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904
[Journal Article] Experimentaldiabetic nephropathy is accelerated in matrix metalloproteinase-2 knockout mice.2013
- Author(s)
  Takamiya Y, Fukami K, Yamagishi S, Kaida Y, Nakayama Y, Obara N, Iwatani R, Ando R, Koike K, Matsui M, Nishino Y, Ueda S, Cooper ME, and Okuda S.
- Journal Title
  
  Nephrol Dial Transplant.
  
  Volume: 28(1) Pages: 55-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904
[Journal Article] Role of advanced glycation end products (AGEs) oxidative stress in vascular complications in diabetes.2012
- Author(s)
  Yamagishi SI, Maeda S, Matsui T, Ueda S, Fukami K, Okuda S.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1820(5) Pages: 663-671
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904
[Journal Article] Decreased serum carnitine is independently correlated with increased tissue accumulation levels of advanced glycation end products in hemodialysis patients.2012
- Author(s)
  Adachi T, Fukami K, Yamagishi S, Kaida Y, Ando R, Sakai K, Adachi H
- Journal Title
  
  Otsuka A, Ueda S, Sugi Kand Okuda S. Nephrology
  
  Volume: 17(8) Pages: 689-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904
[Journal Article] Proteinuria elevates asymmetric dimethylarginine levels via protein arginine methyltransferase-1 overexpression in a rat model of nephrotic syndrome.2012
- Author(s)
  Kaida Y, Ueda S, Yamagishi S, Nakayama Y, Ando R, Iwatani R, Fukami K, Okuda S.
- Journal Title
  
  Life sciences
  
  Volume: 24(91) Pages: 301-305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904
[Journal Article] Role of advanced glycation end products (AGEs) and oxidative stress in vascular complications in diabetes2012
- Author(s)
  Yamagishi SI, Maeda S, Matsui T, Ueda S, Fukami K, Okuda S
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1820 Issue: 5 Pages: 663-671
- DOI
  10.1016/j.bbagen.2011.03.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904
[Journal Article] Tissue level of advanced glycation end products (AGEs) is an independent determinant of high sensitive C-reactive protein levels in hemodialysis patients.2011
- Author(s)
  Makio Nagano, Kei Fukami, Sho-ichi Yamagishi, Kazuko Sakai, Yusuke Kaida, Takafumi Matsumoto, Takuma Hazama, Masahiro Tanaka,1 Seiji Ueda, and Seiya Okuda.
- Journal Title
  
  Nephrology.
  
  Volume: 16(3) Pages: 299-303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904
[Journal Article] Beneficial cardiometabolic actions of telmisartan plus amlodipine therapy in elderly patients with poorly controlled hypertension2011
- Author(s)
  Bekki H, Yamamoto K, Sone M, Homma T, Nakata M, Nohara M, Fukami K, Okuda S, Yamagishi S
- Journal Title
  
  Clin Cardiol
  
  Volume: 34 Issue: 4 Pages: 261-265
- DOI
  10.1002/clc.20855
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904
[Journal Article] Beneficial cardiometabolic actions of telmisartan plus amlodipine therapy in elderly patients with poorly controlled hypertension.2011
- Author(s)
  Bekki H, Yamamoto K, Sone M, Homma T, Nakata M, Nohara M, Fukami K, Okuda S, Yamagishi S. C
- Journal Title
  
  lin Cardiol.
  
  Volume: 34(4) Pages: 261-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904
[Journal Article] A new vasculitis activity score for predicting death in myeloperoxidase-antineutrophil cytoplasmic antibody associated vasculitis patients2011
- Author(s)
  Koike K, Fukami K, Yonemoto K, Iwatani R, Obara N, Ueda K, Toyonaga M, Ueda S, Ohara A, Takeda K, Yamagishi S, Okuda S
- Journal Title
  
  Am J Nephrol
  
  Volume: 35 Issue: 1 Pages: 1-6
- DOI
  10.1159/000334357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904, KAKENHI-PROJECT-22700297, KAKENHI-PROJECT-22240073
[Journal Article] A new vasculitis activity score for predicting deathin myeloperoxidase-antineutrophil cytoplasmic antibody associated vasculitis patients.2011
- Author(s)
  Koike K, Fukami K, Yonemoto K, Iwatani R, Obara N, Ueda K,Toyonaga M, Ueda S, Ohara A, Takeda K, Yamagishi S, Okuda S.
- Journal Title
  
  Am J Nephrol.
  
  Volume: 35(1) Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904
[Journal Article] Tissue level of advanced glycation end products (AGEs) is an independent determinant of high sensitive C-reactive protein levels in hemodialysis patients.2011
- Author(s)
  Nagano M, Fukami K
- Journal Title
  
  Nephrology
  
  Volume: 16 Pages: 299-303
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904
[Journal Article] Pigment epithelium-derived factor (PEDF) inhibits proximal tubular cell injury in early diabetic nephropathy by suppressing advanced glycation end products (AGEs)-receptor (RAGE) axis.2011
- Author(s)
  Maeda S, Matsui T, Takeuchi M, Yoshida Y, Yamakawa R, Fukami K, Yamagishi SI.
- Journal Title
  
  Pharmacol Res.
  
  Volume: 63(3) Pages: 241-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904
[Journal Article] Development of enzyme-linked immunosorbent assay system for PEDF and its clinical utility2010
- Author(s)
  Kei Fukami, Sho-ichi Yamagishi
- Journal Title
  
  Curr Mol Med
  
  Volume: 10 Pages: 317-320
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904
[Journal Article] Interstitial Foxp3-positive T cells may predict renal survival in patients with myeroperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA)-associated glomemlonephritis2010
- Author(s)
  Junko Yoshimura, Kei Fukami
- Journal Title
  
  Clin Exp Phannacol Physiol
  
  Volume: 37 Pages: 879-883
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590904
[Journal Article] Irbesartan inhibits advanced glycation end product(AGE)-induced proximal tubular cell injury in vitro by suppressing receptor for AGEs(RAGE)expression2010
- Author(s)
  Matsui T, Yamagishi SI, Takeuchi M, Ueda S, Fukami K
- Journal Title
  
  Pharmacol Res 61
  
  Pages: 34-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Development of enzyme-linked immunosorbent assay system for PEDF and its clinical utility2010
- Author(s)
  Kei Fukami, Sho-ichi Yamagishi, Seiya Okuda
- Journal Title
  
  Curr Mol Med. 10(3)
  
  Pages: 317-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Circulating matrix metalloproteinase-2 is an independent correlate of proteinuria in patients with chronic kidney disease.2009
- Author(s)
  Nagano M, Fukami K
- Journal Title
  
  American Journal of Nephrology 29
  
  Pages: 109-115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Nifedipine, a calcium channel blocker, inhibits advanced glycation end product (AGE)-elicited mesangial cell damage by suppressing AGE receptor (RAGE) expression via peroxisome proliferator-activated receptor-gamma activation2009
- Author(s)
  Matsui T, Yamagishi S, Takeuchi M, Ueda S, Fukami K, Okuda S.
- Journal Title
  
  Biochem Biophys Res Commun. 385
  
  Pages: 269-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] RAGE-lnduced Cytosolic ROS Promote Mitochondrial Superoxide Generation in Diabetes.2009
- Author(s)
  Coughlan MT, Fukami K
- Journal Title
  
  J Am Soc Nephrol 20
  
  Pages: 742-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] RAGE-Induced Cytosolic ROS Promote Mitochondrial Superoxide Generation in Diabetes.2009
- Author(s)
  Coughlan MT, Thorburn DR, Penfold SA, Laskowski A, Harcourt BE, Sourris KC, Tan AL, Fukami K, Thallas-Bonke V, Nawroth PP, Brownlee M, Bierhaus A, Cooper ME
- Journal Title
  
  Forbes JM. J Am Soc Nephrol. 20
  
  Pages: 742-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Positive association of serum levels of advanced glycation end products and high mobility group box-1 with asymmetric dimethylarginine in nondiabetic chronic kidney disease patients.2009
- Author(s)
  Nakamura T, Sato E, Fujiwara N, Kawagoe Y, Ueda Y, Suzuki T, Yamada S, Takeuchi M, Fukami K, Ueda S, Adachi H, Matsui T, Okuda S
- Journal Title
  
  Yamagishi SI. Metabolism. 3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Protective role of pigment epithelium-derived factor (PEDF) in early phase of experimental diabetic retinopathy.2009
- Author(s)
  Yoshida Y, Yamagishi S, Matsui T, Jinnouchi Y, Fukami K, Imaizumi T, Yamakawa R.
- Journal Title
  
  Diabetes Metab Res Rev 25
  
  Pages: 678-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Protective role of pigment epithelium-derived factor(PEDF)in early phase of experimental diabetic retinopathy2009
- Author(s)
  Yoshida Y, Yamagishi S, Fukami K(5番)
- Journal Title
  
  Diabetes Metab Res Rev 25
  
  Pages: 678-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Circulating matrix metalloproteinase-2 is an independent correlate of proteinuria in patients with chronic kidney disease2009
- Author(s)
  Nagano M, Fukami K(2番)
- Journal Title
  
  Am J Nephrol 29
  
  Pages: 109-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Administration of pigment epithelium-derived factor (PEDF) reduces proteinuria by suppressing decreased nephrin and increased VEGF expression in the glomeruli of adriamycin-injected rats.2009
- Author(s)
  Fujimura T, Yamagishi SI, Ueda S, Fukami K, Shibata R, Matsumoto Y, Kaida Y, Hayashida A, Koike K, Matsui T, Nakamura KI, Okuda S.
- Journal Title
  
  Nephrol Dial Transplant. 24
  
  Pages: 1397-406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Involvement of asymmetric dimethylarginine (ADMA) in glomerular capillary loss and sclerosis in a rat model of chronic kidney disease (CKD)2009
- Author(s)
  Ueda S, Yamagishi SI, Matsumoto Y, Kaida Y, Fujimi-Hayashida A, Koike K, Tanaka H, Fukami K, Okuda S.
- Journal Title
  
  Life Sci. 84
  
  Pages: 853-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Irbesartan inhibits advanced glycation end product (AGE)-induced proximal tubular cell injury in vitro by suppressing receptor for AGEs (RAGE) expression.2009
- Author(s)
  Matsui T, Yamagishi SI, Takeuchi M, Ueda S, Fukami K, Okuda S.
- Journal Title
  
  Pharmacol Res. 25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Circulating matrix metalloproteinase-2 is an independent correlate of proteinuria in patients with chronic kidney disease2009
- Author(s)
  Nagano M, Fukami K, Yamagishi S, Ueda S, Kaida Y, Matsumoto T, Yoshimura J, Hazama T, Takamiya Y, Kusumoto T, Gohara S, Tanaka H, Adachi H, Okuda S.
- Journal Title
  
  Am J Nephrol 29
  
  Pages: 109-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] IL-1RI deficiency ameliorates early experimental renal interstitial fibrosis2009
- Author(s)
  Jones LK, O'Sullivan KM, Semple T, Kuligowski MP, Fukami K, Ma FY, Nikolic-Paterson DJ, Holdsworth SR
- Journal Title
  
  Kitching AR. Nephrol Dial Transplant. 24
  
  Pages: 3024-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Involvement of asymmetric dimethylarginine (ADMA) in tubulointerstitial ischaemia in the early phase of diabetic nephropathy.2009
- Author(s)
  Shibata R, Ueda S, Yamagishi SI, Kaida Y, Matsumoto Y, Fukami K, Hayashida A, Matsuoka H, Kato S, Kimoto M, Okuda S.
- Journal Title
  
  Nephrol Dial Transplant. 24
  
  Pages: 1162-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Clinical Utility of Acarbose, an alpha-Glucosidase Inhibitor in Cardiometabolic Disorders2009
- Author(s)
  Yamagishi S, Matsui T, Ueda S, Fukami K, Okuda S.
- Journal Title
  
  Curr Drug Metab. 10
  
  Pages: 159-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Olmesartan blocks advanced glycation end products (AGEs)-induced angiogenesis in vitro by suppressing receptor for AGEs (RAGE) expression.2008
- Author(s)
  Yamagishi SI, Matsui T, Nakamura K, Inoue H, Takeuchi M, Ueda S, Fukami K, Okuda S, Imaizumi T.
- Journal Title
  
  Microvasc Res. 75
  
  Pages: 130-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Olmesartan blocks advanced glycation end products (AGEs)-induced angiogenesis in vitro by suppressing receptor for AGEs (RAGE) expression2008
- Author(s)
  Yamagishi S, Matsui T, Nakamura K, Inoue H, Takeuchi M, Ueda S, Fukami K, Okuda S, Imaizumi T.
- Journal Title
  
  Microvasc Res. 75
  
  Pages: 130-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Administration of pigment epithelium-derived factor (PEDF) reduces proteinuria by suppressing decreased nephrin and increased VEGF expression in the glomeruli of adriamycin-iniected rats.2008
- Author(s)
  Fujimura T, Fukami K
- Journal Title
  
  Nephrol Dial Transplant. 24
  
  Pages: 1397-1406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathway.2008
- Author(s)
  Thallas-Bonke V, Thorpe SR, Coughlan MT, Fukami K, Yap FY, Sourris KC, Penfold SA, Bach LA, Cooper ME
- Journal Title
  
  Forbes JM. Diabetes. 57
  
  Pages: 460-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Agents that block advanced glycation end product (AGE)-RAGE (receptor for AGEs)-oxidative stress system: a novel therapeutic strategy for diabetic vascular complications2008
- Author(s)
  Yamagishi S, Nakamura K, Matsui T, Ueda S, Fukami K, Okuda S.
- Journal Title
  
  Expert Opin Investig Drugs. 17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Role of AGEs in diabetic nephropathy2008
- Author(s)
  Fukami K, Yamagishi S, Ueda S, Okuda S.
- Journal Title
  
  Curr Pharm Des. 14
  
  Pages: 946-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Plasminogen activator inhibitor-1 expression is pathogenetic in experimental murine diabetic renal disease Diabetologia2007
- Author(s)
  M. Lassila, K. Fukami, Jandeleit-Dahm, T. Semple, P. Carmeliet, M.E. Cooper, A.R. Kitching
- Journal Title
  
  50
  
  Pages: 1315-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Possible involvument of AGE and MMP-2 in podocyte detachment and loss2007
- Author(s)
  Kei Fukami, Sho-ichi Yamagishi, Seiji Ueda, Hiroshi Kawachi, Masavoshi Takeuchi, Seiya Okuda
- Journal Title
  
  Journal of the American Society of Nephrology 18
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Novel therapeutic targets for diabetic nephropathy2007
- Author(s)
  Kei Fukami, Sho-ichi Yamagishi, Seiji Ueda, Seiya Okuda
- Journal Title
  
  Endocr Metab ImmuneDisord Drug Targets 7
  
  Pages: 83-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Journal Article] Role of AGEs in Diabetic Nephropathy2007
- Author(s)
  Kei Fukami, Sho-ichi Yamagishi, Seiji Ueda, Seiya Okuda
- Journal Title
  
  Current Pharmaceutical Design (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590970
[Patent] AGE特異的アプタマーの腎疾患治療用途2013
- Inventor(s)
  深水　圭
- Industrial Property Rights Holder
  深水　圭
- Industrial Property Rights Type
  特許
- Filing Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-22590904
[Patent] AGE特異的アプタマーの腎疾患治療用途2011
- Inventor(s)
  深水圭
- Industrial Property Rights Holder
  深水圭、山岸昌一、井上浩義、奥田誠也
- Filing Date
  2011-11-24
- Overseas
- Data Source
  KAKENHI-PROJECT-22590904
[Presentation] Characterization of regulatory B cells and IL-10 in response to ischemic reperfusion2023
- Author(s)
  Kei Fukami
- Organizer
  World Congress of Nephrology 2023 Bankock
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08370
[Presentation] Production of the regulatory cytokine IL-10 in renal ischemia-reperfusion injury2022
- Author(s)
  Yunosuke Yokota, Goh Kodama, Sakuya Ito, Makoto Nasu, Yusuke Kaida, Mitsushi Mizoguchi, Kei Fukami
- Organizer
  World Congress of Nephrology 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08693
[Presentation] Characterization of regulatory B cells and IL-10 in response to ischemic reperfusion2022
- Author(s)
  Yu-nosuke Yokota , Kensei Taguchi , Sakuya Ito, Goh Kodama, Kei Fukami
- Organizer
  American Society of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08370
[Presentation] 腎虚血再灌流傷害における調節サイトカインIL-10の産生について2022
- Author(s)
  横田祐之介, 児玉豪, 伊藤佐久耶, 那須誠, 甲斐田裕介, 溝口充志, 深水圭
- Organizer
  第65回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-22K08370
[Presentation] 腎虚血再灌流傷害モデルにおける調節性サイトカインIL-10誘導2021
- Author(s)
  横田祐之介, 児玉豪, 伊藤佐久耶, 那須誠, 甲斐田裕介, 溝口充志, 深水圭
- Organizer
  日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-19K08693
[Presentation] 糖尿病性腎臓病における心筋障害発症メカニズムと治療を考える2020
- Author(s)
  深水　圭
- Organizer
  第63回日本腎臓学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08693
[Presentation] 腹膜透析患者に対する集学的管理2020
- Author(s)
  深水　圭
- Organizer
  第65回日本透析医学会学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08693
[Presentation] Inhibitory Effects of RAGE Aptamer on Proliferation of Smooth Muscle Cells from Pulmonary Arterial Hypertension2019
- Author(s)
  Kazufumi Nakamura 、Satoshi Akagi 、Kentaro Ejiri 、Toru Miyoshi 、Masashi Yoshida 、Kei Fukami 、Hiroshi Ito
- Organizer
  第 83 回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08037
[Presentation] Increased sodium chloride cotransporter expression in a rat remnant kidney model2017
- Author(s)
  Sakuya Ito, Kensei Taguchi, Yosuke Nakayama, Yusuke Kaida, Eisei Sohara, Shinichi Uchida, Kei Fukami
- Organizer
  ERA-EDTA 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09637
[Presentation] AGEs-RAGE system as a promising therapeutic target for diabetic kidney disease2017
- Author(s)
  Kei Fukami
- Organizer
  ERA-EDTA 2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09637
[Presentation] 腎不全モデルラットにおけるNa-Cl共輸送体(NCC)発現の検討2017
- Author(s)
  伊藤佐久耶、田口顕正、安藤亮太郎、中山陽介、甲斐田裕介、蘇原映誠、内田信一、深水圭
- Organizer
  日本腎臓学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09637
[Presentation] DNA-aptamer raised against RAGE improves the development of lupus nephritis in MRL/lpr mice2017
- Author(s)
  Kensei Taguchi, Akito Maeshima, Sho-ichi Yamagishi, Yosuke Nakayama, Yusuke Kaida, Yuichiro Higashimoto, Yasuhiko Yamamoto , Craig Brooks, Kei Fukami
- Organizer
  ASN 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09637
[Presentation] DNA-aptamer raised against AGEs-RAGE system as a novel therapeutic tool for the development of diabetic and hypertensive nephropathy2015
- Author(s)
  Kei Fukami
- Organizer
  Chinese Society of Nephrology
- Place of Presentation
  Zhuhai City, China
- Year and Date
  2015-11-19
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461239
[Presentation] DNA aptamer raised against AGEs improves diabetic nephropathy in KK/Ay-Ta mice2013
- Author(s)
  深水　圭
- Organizer
  日本循環器学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22590904
[Presentation] DNA aptamer raised against AGEs improves diabetic nephropathy in KK/Ay-Ta miceNana Obara2012
- Author(s)
  Kei Fukami, Sho-ichi Yamagishi, Yusuke Kaida, Yuichiro Higashimoto, Masayoshi Takeuchi, Seiji Ueda, Hiroyoshi Inoue, Seiya Okuda.
- Organizer
  2012 International Symposium on the Maillard Reaction | IMARS.
- Place of Presentation
  Nancy, France
- Data Source
  KAKENHI-PROJECT-22590904
[Presentation] DNA aptamers raised against AGEs improve diabetic nephropathy in KK/Ay-Ta mice2011
- Author(s)
  Kei Fukami, Sho-ichi Yamagishi
- Organizer
  国際腎臓病学会
- Place of Presentation
  カナダ・バンクーバー
- Year and Date
  2011-04-10
- Data Source
  KAKENHI-PROJECT-22590904
[Presentation] AGEs-DNAアプタマーは糖尿病腎症の糸球体硬化を改善する2011
- Author(s)
  甲斐田裕介、深水圭
- Organizer
  日本腎臓学会
- Place of Presentation
  横浜
- Year and Date
  2011-05-12
- Data Source
  KAKENHI-PROJECT-22590904
[Presentation] AGEs-DNAアプタマーは糖尿病腎症の糸球体硬化を改善する2011
- Author(s)
  甲斐田裕介、深水圭、上田誠二、山岸昌一、奥田誠也
- Organizer
  日本腎臓学会学術集会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22590904
[Presentation] DNA aptamers raised against AGEs improve diabetic nephropathy in KK/Ay-Ta mice.2011
- Author(s)
  Yusuke Kaida , Kei Fukami, Sho-ichiYamagishi, Yuichiro Higashimoto, Nana Obara, Ryotaro Ando, Yosuke Nakayama, Masayoshi Takeuchi, Takanori Matsui, Seiji Ueda, Hiroyoshi Inoue, Seiya Okuda.
- Organizer
  American Society of Nephrology.
- Place of Presentation
  Philadelphia, Pennsylvania
- Data Source
  KAKENHI-PROJECT-22590904
[Presentation] DNA aptamers raised against AGEs improve diabetic nephropathy in KK/Ay-Ta mice2011
- Author(s)
  Yusuke Kaida, Kei Fukami
- Organizer
  アメリカ腎臓病学会
- Place of Presentation
  アメリカ・フィラデルフィア
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-22590904
[Presentation] Possible involvement of AGE and MMP-2 in podocyte detachment and loss. Roma.2008
- Author(s)
  Fukami K, Takamiya Y, Yamagishi S, Ueda S, Takeuchi M, Okuda S
- Organizer
  Diabetologia
- Place of Presentation
  EASD
- Data Source
  KAKENHI-PROJECT-19590970
[Presentation] Possible involvement of AGE and MMP-2 in podocyte detachment and loss.2008
- Author(s)
  Fukami K
- Organizer
  ヨーロッパ糖尿病学会
- Place of Presentation
  Roma
- Year and Date
  2008-09-10
- Data Source
  KAKENHI-PROJECT-19590970
[Presentation] Possible involvement of AGE and MMP-2 in podocyte detachment and loss.2007
- Author(s)
  Fukami K, Takamiya Y, Yamagishi S, Ueda S, Takeuchi M, Okuda S
- Organizer
  Amsterdam. Diabetologia
- Place of Presentation
  EASD
- Data Source
  KAKENHI-PROJECT-19590970
[Presentation] Possible involvement of AGE and MMP-2 in podocyte detachment and loss2007
- Author(s)
  Kei Fukami, Sho-ichi Yamagishi, Seiji Ueda, Hiroshi Kawachi, Masayoshi Thkeuchi, Seiya Okuda
- Organizer
  The European Association for the Study of Diabetes
- Place of Presentation
  アムステルダム
- Year and Date
  2007-09-19
- Data Source
  KAKENHI-PROJECT-19590970
[]

1. UEDA Seiji (80322593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
2. Shibata Ryo (10723588)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. Nakamura Kazufumi (10335630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. Kaida Yusuke (80441658)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 赤木達 (60601127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 阪口政清 (70379840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 三好亨 (70444651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 伊藤浩 (90446047)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. TAGUCHI kensei

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MITSUYAMA Keichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. YAMASAKI Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. MATSUI Takanori

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
13. 東元祐一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 副島美貴子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 神田芳郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 山岸昌一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

FUKAMI Kei 深水 圭

深水 圭 フカミ ケイ

Research Projects

Research Products

Co-Researchers

免疫応答性Breg細胞輸注療法の確立とAKI-to-CKD進展に対する治療への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Breg-IL-10 system as a novel therapeutic target in AKI-to-CKDPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Breg-IL-10 system as a novel therapeutic target for CKDPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Toward a Model District for CKD Prevention Starting with Maternal and Child Health

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of new treatments with RAGE-aptamer-incorporated nanoparticles for pulmonary arterial hypertension

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The efficacy of RAGE-DNA aptamer for prevention of hypertensive nephropathy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The mechanism of brain-renal interaction on metabolic syndrome-role of AGEs-RAGE system-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Maternal exposure to high-fat and high-fructose diet evokes hypoadiponectinemia and kidney injury in rat offspring.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel therapeutic approach against receptor for advanced glycation end products in patients with diabetic nephropathy or RPGN.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Tubulointerstitial injury is exacerbated in streptozotocin-induced diabetic matrix metalloproteinase-2 knockout micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

可溶性IL-12受容体を用いた半月体形成糸球体腎炎に対する遺伝子治療の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Pharma Medica2020

Author(s)

Total Pages

Publisher

Data Source

[Book] 臨床透析2020

Author(s)

Total Pages

Publisher

FUKAMI Kei 深水圭

深水圭フカミケイ

[Book] 留米医学会雑誌終末糖化産物からみた慢性腎臓病(CKD)の病態解明と治療戦略2011