MEKATA Eiji 目片英治

… Alternative Names

目片英治メカタエイジ

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Researcher Number	80314152
Other IDs
Affiliation (Current)	2025: 滋賀医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2025: 滋賀医科大学, 医学部, 教授 2015 – 2023: 滋賀医科大学, 医学部, 教授 2011 – 2014: 滋賀医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related / Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Basic Section 55020:Digestive surgery-related / Digestive surgery / Applied health science / Radiation science
Keywords	Principal Investigator 免疫チェックポイント阻害薬 / CTL / 癌免疫細胞療法 / OX40 / 免疫寛容 / mB7-DC-Fc / LAP吸着カラム / 制御性T細胞 / 免疫チェックポイント / 抗体治療 … More / 細胞免疫治療 / 癌免疫治療 / LAP陽性細胞吸着カラム / エフェクター機能増強 / T細胞補助刺激 / がん免疫細胞治療 / 抗PD-L2抗体 / 免疫チェックポイント阻害剤 / OX40補助刺激 / TGF-β陽性細胞除去カラム / PD-L2 / PD-1 / LAP / 複合的免疫療法 / 抗腫瘍免疫 … More Except Principal Investigator OX40補助刺激 / 養子免疫 / 免疫細胞治療 / 抗OX40 抗体 / LAP吸着カラム / TAL / 難治性がん性腹水 / 腹膜播種性転移 / がん性腹水 / 免疫チェックポイント阻害剤 / CTL / 免疫チェックポイント阻害薬 / OX40 / 腹膜播種 / 免疫寛容 / 癌免疫細胞療法 / がん抗原特異的CTL / PD-1阻害薬 / がん抗原ペプチド / 癌性胸水・腹水 / 胸膜・腹膜転移 / 免疫チェックポイント / 免疫治療 / 細胞治療 / 腫瘍免疫 / 免疫チェックポイント阻害 / 補助刺激 / 抗体療法 / 子宮頸がん / 乳がん / 未受診者対策 / 産業保健 / 啓発 / 波及効果 / 生活習慣病 / 啓発媒体開発 / 無作為化 / 介入研究 / 行動変容 / 女性 / 職域 / 受診勧奨 / がん検診 / 骨盤底筋群 / 便失禁 / 骨盤機能 / 縦型MR / 肛門機能 / 直腸機能 / 骨盤底筋 / 潰瘍性大腸炎 / 直腸癌 / 直腸脱 / 縦型MRI Less

がん免疫逃避に打ち勝つ複合的がん免疫細胞療法の開発Principal Investigator
- Principal Investigator
  
  目片英治
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Shiga University of Medical Science
がんの免疫逃避を克服する複合的がん免疫細胞療法の開発Principal Investigator
- Principal Investigator
  
  目片英治
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Shiga University of Medical Science
Development of new immuno-cell therapy for the treatment of refractory malignant ascites and pleural effusion
- Principal Investigator
  
  Kojima Masatsugu
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Shiga University of Medical Science
Development of complehensive cancer immune cell therapies to overcome immune tolerancePrincipal Investigator
- Principal Investigator
  
  Mekata Eiji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Shiga University of Medical Science
Cancer antigen-specific CTL induction and immune cell therapy using cancer antigen peptide, T cell co-stimulation, and immunosuppressive cell regulation
- Principal Investigator
  
  Miyake Toru
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Shiga University of Medical Science
Effects of public education about breast and uterine cervix cancer screening for female non-regular employment
- Principal Investigator
  
  MIYAMATSU Naomi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Shiga University of Medical Science
The evaluation of ano-rectal function and pelvic floor muscles by sitting position MRI.
- Principal Investigator
  
  ENDO Yoshihiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Shiga University of Medical Science

All 2022 2021 2020 2018 2017 2012 2011 Other

All Journal Article Presentation

[Journal Article] Predictors and clinical impact of postoperative diarrhea after colorectal cancer surgery: a prospective, multicenter, observational study (SHISA-1602)2022
- Author(s)
  Ohta Hiroyuki、Miyake Toru、Ueki Tomoyuki、Kojima Masatsugu、Kawasaki Masayasu、Tatsuta Takeshi、Iuchi Takekazu、Kamitani Sumihiro、Shimizu Tomoharu、Mekata Eiji、Tani Masaji
- Journal Title
  
  International Journal of Colorectal Disease
  
  Volume: 37 Issue: 3 Pages: 657-664
- DOI
  10.1007/s00384-022-04097-8
- NAID
  120007190901
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07936, KAKENHI-PROJECT-19K09196, KAKENHI-PROJECT-20K09285
[Journal Article] INI1-negative colorectal undifferentiated carcinoma with rhabdoid features and postoperative rapidly growing liver metastases: a case report and review of the literature2021
- Author(s)
  Kojima Masatsugu、Miyake Toru、Ueki Tomoyuki、Ohta Hiroyuki、Kushima Ryoji、Shiohara Masanori、Mizuta Hiroo、Iida Hiroya、Yamaguchi Tsuyoshi、Kaida Sachiko、Takebayashi Katsushi、Maehira Hiromitsu、Nishina Yusuke、Shimizu Tomoharu、Mekata Eiji、Tani Masaji
- Journal Title
  
  Surgical Case Reports
  
  Volume: 7 Issue: 1
- DOI
  10.1186/s40792-021-01189-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09196
[Journal Article] In vivo antitumor function of tumor antigen-specific CTLs generated in the presence of OX40 co-stimulation in vitro2018
- Author(s)
  Pham Minh Ngoc、Murata Satoshi、Kitamura Naomi、Ueki Tomoyuki、Kojima Masatsugu、Miyake Toru、Takebayashi Katsushi、Kodama Hirokazu、Mekata Eiji、Tani Masaji
- Journal Title
  
  International Journal of Cancer
  
  Volume: 142 Issue: 11 Pages: 2335-2343
- DOI
  10.1002/ijc.31244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10137, KAKENHI-PROJECT-18K08615
[Presentation] Relationship between CD44-positive cancer stem-like cells and gastric cancer-derived peritoneal metastasis2021
- Author(s)
  Andreas Michael Sihombing1, Satoshi Murata1,2, Miyuki Shimoji1, Sakura Nakao1, Katsushi Takebayashi1, Hirokazu Kodama1, Masatsugu Kojima1, Tomoyuki Ueki1, Naomi Kitamura3, Mina Kitamura1, Aya Tokuda1, Toru Miyake1, Eiji Mekata3, Masaji Tani1
- Organizer
  第80回日本癌学会
- Data Source
  KAKENHI-PROJECT-19K09196
[Presentation] Induction of tumor Ag-specific CTL using tumor-associated lymphocytes (TAL) in malignant ascites of immune-tolerant mice2021
- Author(s)
  Satoshi Murata, Miyuki Shimoji, Masatsugu Kojima, Mina Kitamura, Andreas Michael Sihombing, Sakura Nakao, Naomi Kitamura, Tomoyuki Ueki, Katsushi Takebayashi, Hirokazu Kodama, Aya Tokuda, Toru Miyake, Eiji Mekata, Masaji Tani
- Organizer
  第80回日本癌学会
- Data Source
  KAKENHI-PROJECT-19K09196
[Presentation] Crosstalk of microsomal glutathione transferase 1 (MGST1) and CD44 in T3M4 human pancreatic cancer cells on hyperthermic model2021
- Author(s)
  Miyuki Shimoji1, Satoshi Murata1,2, Andreas Michael Sihombing1, Sakura Nakao1, Katsushi Takebayashi1, Hirokazu Kodama1, Masatsugu Kojima1, Tomoyuki Ueki1, Naomi Kitamura3, Mina Kitamura1, Aya Tokuda1, Toru Miyake1, Eiji Mekata3, Masaji Tani1
- Organizer
  第80回日本癌学会
- Data Source
  KAKENHI-PROJECT-19K09196
[Presentation] Overcoming immune tolerance to tumor antigens and inducing tumor antigen-specific CTLs by combined immunotherapy2021
- Author(s)
  Sakura Nakao, Satoshi Murata, Miyuki Shimoji, Masatsugu Kojima, Mina Kitamura, Andreas Michael Sihombing, Naomi Kitamura, Tomoyuki Ueki, Katsushi Takebayashi, Hirokazu Kodama, Aya Tokuda, Toru Miyake, Eiji Mekata, Masaji Tani
- Organizer
  第80回日本癌学会
- Data Source
  KAKENHI-PROJECT-19K09196
[Presentation] CD44+ cancer cells in the free peritoneal cavity and surgical manipulation as the cause of gastric cancer-derived peritoneal metastasis2021
- Author(s)
  Andreas Michael Sihombing1, Satoshi Murata1,2, Miyuki Shimoji1, Sakura Nakao1, Katsushi Takebayashi1, Hirokazu Kodama1, Masatsugu Kojima1, Tomoyuki Ueki1, Naomi Kitamura3, Mina Kitamura1, Aya Tokuda1, Toru Miyake1, Eiji Mekata3, Masaji Tani1
- Organizer
  JCA-AACR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09196
[Presentation] Characterization of Tumor-associated lymphocytes (TAL) in malignant ascites of immune-tolerant mice2021
- Author(s)
  Miyuki Shimoji 1), Satoshi Murata 2), Masatsugu Kojima 1), Mina Kitamura 1), Andreas Michael Sihombing 1), Sakura Nakao 1), Naomi Kitamura 3), Tomoyuki Ueki 1), Katsushi Takebayashi 1), Hirokazu Kodama 1), Aya Tokuda 1), Toru Miyake 1), Eiji Mekata 3), Masaji Tani 1)
- Organizer
  JCA-AACR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09196
[Presentation] Therapeutic strategy based on the mechanism of peritoneal relapse after surgery for gastric cancer2020
- Author(s)
  Satoshi Murata, Katsushi Takebayashi, Tsuyoshi Yamaguchi, Sachiko Kaida, Ken Ishikawa, Hirokazu Kodama, Miyuki Shimoji, Andreas Michael Sihombing, Masatsugu Kojima, Toru Miyake, Hiroya Iida, Tomoyuki Ueki, Mina Kitamura, Aya Tokuda, Eiji Mekata, Masaji Tani
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09196
[Presentation] Effect of hyperthermia on the cancer stem-like cells2020
- Author(s)
  Miyuki Shimoji, Satoshi Murata, Andreas Michael Sihombing, Katsushi Takebayashi, Hirokazu Kodama, Masatsugu Kojima, Tomoyuki Ueki, Naomi Kitamura, Mina Kitamura, Aya Tokuda, Toru Miyake, Eiji Mekata, Masaji Tani.
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09196
[Presentation] Effect of hyperthermia on the cancer stem-like cells2020
- Author(s)
  Miyuki Shimoji, Satoshi Murata, Andreas Michael Sihombing, Katsushi Takebayashi, Hirokazu Kodama, Masatsugu Kojima, Tomoyuki Ueki, Naomi Kitamura, Mina Kitamura, Aya Tokuda, Toru Miyake, Eiji Mekata, Masaji Tani.
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08615
[Presentation] CD44-enriched cancer stem-like cells as a source of peritoneal metastasis from gastric cancer2020
- Author(s)
  Andreas Michael Sihombing, Satoshi Murata, Miyuki Shimoji, Katsushi Takebayashi, Hirokazu Kodama, Masatsugu Kojima, Tomoyuki Ueki, Naomi Kitamura, Mina Kitamura, Aya Tokuda, Toru Miyake, Eiji Mekata, Masaji Tani
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09196
[Presentation] Therapeutic strategy based on the mechanism of peritoneal relapse after surgery for gastric cancer2020
- Author(s)
  Satoshi Murata, Katsushi Takebayashi, Tsuyoshi Yamaguchi, Sachiko Kaida, Ken Ishikawa, Hirokazu Kodama, Miyuki Shimoji, Andreas Michael Sihombing, Masatsugu Kojima, Toru Miyake, Hiroya Iida, Tomoyuki Ueki, Mina Kitamura, Aya Tokuda, Eiji Mekata, Masaji Tani
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08615
[Presentation] Tumor Ag-specific CTL generation from tumor-associated lymphocytes (TAL) in malignant ascites of peritoneal metastases2020
- Author(s)
  Masatsugu Kojima, Satoshi Murata, Miyuki Shimoji, Andreas Michael Sihombing, Naomi Kitamura, Tomoyuki Ueki, Mina Kitamura, Katsushi Takebayashi, Hirokazu Kodama, Aya Tokuda, Toru Miyake, Eiji Mekata, Masaji Tani
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09196
[Presentation] CD44-enriched cancer stem-like cells as a source of peritoneal metastasis from gastric cancer2020
- Author(s)
  Andreas Michael Sihombing, Satoshi Murata, Miyuki Shimoji, Katsushi Takebayashi, Hirokazu Kodama, Masatsugu Kojima, Tomoyuki Ueki, Naomi Kitamura, Mina Kitamura, Aya Tokuda, Toru Miyake, Eiji Mekata, Masaji Tani
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08615
[Presentation] Tumor Ag-specific CTL generation from tumor-associated lymphocytes in malignant ascites of peritoneal metastases2020
- Author(s)
  Masatsugu Kojima, Satoshi Murata, Miyuki Shimoji, Andreas Michael Sihombing, Naomi Kitamura, Tomoyuki Ueki, Mina Kitamura, Katsushi Takebayashi, Hirokazu Kodama, Aya Tokuda, Toru Miyake, Eiji Mekata, Masaji Tani
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08615
[Presentation] 細胞移入後に担癌生体内で増殖できる腫瘍特異的CTL細胞療法2018
- Author(s)
  村田　聡、Pham Minh Ngoc、北村直美、河合由紀、梅田朋子、目片英治、森毅、冨田香、北村美奈、田中彰恵、清水智治、谷眞至
- Organizer
  第26回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08615
[Presentation] Immunological activities of adoptively transferred tumor antigen-specific CTLs costimulated with OX40 signaling in vitro2017
- Author(s)
  Pham Minh Ngoc, Satoshi Murata, Naomi Kitamura, Tomoyuki Ueki, Masatsugu Kojima, Toru Miyake, Katsushi Takebayashi, Hirokazu Kodama, Yuki Kawai, Yataro Daigo, Eiji Mekata, Masaji Tani
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K10137
[Presentation] 座位MRIによる直腸脱症例の評価2012
- Author(s)
  遠藤善裕、清水智治、目片英治、園田寛道、赤堀浩也、三宅　亨、谷　徹
- Organizer
  第67回　日本大腸肛門病学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23591764
[Presentation] 座位MRIによる直腸脱症例の評価2012
- Author(s)
  遠藤善裕、清水智治、目片英治、園田寛道、赤堀浩也、三宅亨、谷徹
- Organizer
  第67回日本大腸肛門病学会学術集会
- Data Source
  KAKENHI-PROJECT-23591764
[Presentation] 大腸癌同時性肝肺転移に対する新たな治療戦略-VATS+IVMR-MCTによる低侵襲同時手術の経験2012
- Author(s)
  園田寛道, 清水智治, 塩見尚礼, 仲成幸, 目片英治, 遠藤善裕, 橋本雅之, 北村将司, 寺本晃司, 花岡淳, 手塚則明, 来見良誠, 谷徹
- Organizer
  第74回日本臨床外科学会総会
- Data Source
  KAKENHI-PROJECT-23591764
[Presentation] 座位MRIによる排便機能検査2011
- Author(s)
  清水智治, 遠藤善裕, 龍田健, 目片英治, 谷徹
- Organizer
  第36回日本外科系連合学会学術集会
- Data Source
  KAKENHI-PROJECT-23591764
[Presentation] ナビゲーションサージェリーの有用性と今後の展望MRI navigation surgeryシステムによる直腸癌骨盤内再発に対する局所治療2011
- Author(s)
  清水智治, 遠藤善裕, 目片英治, 山本寛, 村田聡, 塩見尚礼, 仲成幸, 森川茂廣, 来見良誠, 谷徹
- Organizer
  第36回日本外科系連合学会学術集会
- Data Source
  KAKENHI-PROJECT-23591764
[Presentation] The effect of emotional information on breast cancer screening attendance: A randomized controlled trial.
- Author(s)
  Godai K, Shima A, Tanaka H, Okamura T, Mekata E, Kimura T, Kawatsu Y, Miyamatsu N.
- Organizer
  第25回日本疫学会学術総会
- Place of Presentation
  ウインクあいち（名古屋）
- Year and Date
  2015-01-21 – 2015-01-23
- Data Source
  KAKENHI-PROJECT-24500814

1. MURATA Satoshi (90239525)

# of Collaborated Projects: 5 results

# of Collaborated Products: 18 results
2. 谷眞至 (60236677)

# of Collaborated Projects: 4 results

# of Collaborated Products: 18 results
3. SHIMIZU Tomoharu (70402708)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. Miyake Toru (70581924)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. Kojima Masatsugu (10452236)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
6. ENDO Yoshihiro (40263040)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. TANI Tohru (20179823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. KATAYAMA Ikuko (40437132)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SONODA Hiromichi (80437152)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. MURAKAMI Koichiro (30572763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MORIKAWA Shigehiro (60220042)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. MIYAMATSU Naomi (90314145)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. OKAMURA Tomonori (00324567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
14. SHIMA Azusa (20635958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. TANAKA Hideo (60470168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. GODAI Kayo (30708681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. MORINAGA Miho (60324571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 北村直美 (30572474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. 下地みゆき (50796448)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. Pham Minh Ngoc

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results

MEKATA Eiji 目片 英治

目片 英治 メカタ エイジ

Research Projects

Research Products

Co-Researchers

がん免疫逃避に打ち勝つ複合的がん免疫細胞療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

がんの免疫逃避を克服する複合的がん免疫細胞療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of new immuno-cell therapy for the treatment of refractory malignant ascites and pleural effusion

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of complehensive cancer immune cell therapies to overcome immune tolerancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cancer antigen-specific CTL induction and immune cell therapy using cancer antigen peptide, T cell co-stimulation, and immunosuppressive cell regulation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of public education about breast and uterine cervix cancer screening for female non-regular employment

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The evaluation of ano-rectal function and pelvic floor muscles by sitting position MRI.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Predictors and clinical impact of postoperative diarrhea after colorectal cancer surgery: a prospective, multicenter, observational study (SHISA-1602)2022

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] INI1-negative colorectal undifferentiated carcinoma with rhabdoid features and postoperative rapidly growing liver metastases: a case report and review of the literature2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In vivo antitumor function of tumor antigen-specific CTLs generated in the presence of OX40 co-stimulation in vitro2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] Relationship between CD44-positive cancer stem-like cells and gastric cancer-derived peritoneal metastasis2021

Author(s)

Organizer

Data Source

[Presentation] Induction of tumor Ag-specific CTL using tumor-associated lymphocytes (TAL) in malignant ascites of immune-tolerant mice2021

Author(s)

Organizer

Data Source

[Presentation] Crosstalk of microsomal glutathione transferase 1 (MGST1) and CD44 in T3M4 human pancreatic cancer cells on hyperthermic model2021

Author(s)

Organizer

Data Source

[Presentation] Overcoming immune tolerance to tumor antigens and inducing tumor antigen-specific CTLs by combined immunotherapy2021

Author(s)

Organizer

Data Source

[Presentation] CD44+ cancer cells in the free peritoneal cavity and surgical manipulation as the cause of gastric cancer-derived peritoneal metastasis2021

MEKATA Eiji 目片英治

目片英治メカタエイジ