Arai Naoya 新井直也

… Alternative Names

新井直也アライナオヤ

ARAI Naoya 新井直也

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Researcher Number	80323723
Other IDs
External Links
Affiliation (Current)	2025: 三重大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2019 – 2021: 三重大学, 医学系研究科, 教授 2013 – 2014: 三重大学, 医学(系)研究科(研究院), 教授 2013: 三重大学, 大学院医学系研究科, 教授 2012: 富山大学, その他の研究科, 准教授 2012: 富山大学, 大学院医学薬学研究部(医学), 准教授 … More 2011: 富山大学, 医学薬学研究部(医学), 准教授 2010: 富山大学, 大学院・医学薬学研究部(医学), 准教授 2008 – 2010: 富山大学, 大学院・医学薬学研究部, 准教授 2001 – 2003: 東京医科歯科大学, 大学院・医歯学総合研究科, 助手 Less
Review Section/Research Field	Principal Investigator Surgical dentistry Except Principal Investigator Surgical dentistry / Basic Section 57060:Surgical dentistry-related / Surgical dentistry
Keywords	Principal Investigator 上皮細胞 / 相乗作用 / 細胞毒性 / カルシウム / ビスフォスフォネート Except Principal Investigator AMF / 免疫 / 口腔癌 / 顎骨浸潤 / リン酸カルシウム … More / 粘膜為害作用 / 顎骨壊死 / カルシウム塩 / 粘膜為害性 / BRONJ / ビスフォスフォネート / cyclin / gene therapy / vaccine / cytokine / cell cycle / oral cancer / サイクリン / 遺伝子治療 / ワクチン / サイトカイン / 細胞周期 / 免疫学 / 破骨細胞分化 / アポートシス / ピスホスホネート製剤 / ピスホスホネート製 / 扁平上皮癌 / アポトーシス / ビスホスホネート製剤 / 破骨細胞分化誘導因子 / 破骨細胞 / 口腔扁平上皮癌 Less

Analysis of the mucous membrane damaging effect of the complex of bisphosphonate and calcium salt
- Principal Investigator
  
  Kurohara Kazuto
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Mie University
An in vitro study on the role of calcium in bisphosphonate-related osteonecrosis of jaw.Principal Investigator
- Principal Investigator
  
  ARAI Naoya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Mie University
  University of Toyama
A novel strategy against bone invasion of oral cancer
- Principal Investigator
  
  NOGUCHI Makoto
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  University of Toyama
Type of bone invasion in human or al squamous cell carcinoma and its mechanisms ; application for molecular diagnosis
- Principal Investigator
  
  NOGUCHI Makoto
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  University of Toyama
Gene therapy for oral cancer by cell cycle regulators and tumor vaccine genetically mokified to secrete cytokines.
- Principal Investigator
  
  YAMAGUCHI Satoshi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Tokyo Medical and Dental University

All 2020 2014 2013 2012 2011 2010 2009 2008 2002 2001 Other

All Journal Article Presentation

[Journal Article] Gemcitabine chemotherapy induces phenotypic alterations of tumor cells that facilitate antitumor T cell responses in a mouse model of oral cancer2014
- Author(s)
  Tomihara K, Fuse H, Heshiki W, Takei R, Zhang B, Arai N, Nakamori K, Noguchi M
- Journal Title
  
  Oral Oncol
  
  Volume: 50 Pages: 457-467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592957
[Journal Article] CD44 and SSEA-4 positive cells in an oral cancer cell line HSC-4 possess cancer stem-like cell characteristics2013
- Author(s)
  Noto Z, Yoshida T, Okabe M, Koike C, Fathy M, Tsuno H, Tomihara K, Arai N, Noguchi M, Nikaido T
- Journal Title
  
  Oral Oncol
  
  Volume: 49 Pages: 787-795
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592957
[Journal Article] In vitro synergistic effects of zoledronic acid and calcium on viability of human epithelial cells2013
- Author(s)
  Arai N, Inoue S, Tomihara K, Tsuno H, Noguchi M
- Journal Title
  
  Oral Dis
  
  Volume: 19 Pages: 200-205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592957
[Journal Article] Heparin induces apoptosis through suppression of AKt in oral squamous cell carcinoma cells.2009
- Author(s)
  Ueda K., Inoue S., Zhang Y., Kutsuna T., Inoue S., Noto K., Arai N., Noguchi M.
- Journal Title
  
  Anticancer research 29
  
  Pages: 1079-1088
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592356
[Journal Article] 口腔扁平上皮癌細胞の遊走様式についての研究2002
- Author(s)
  新中康史, 新井直也, 山口聰他
- Journal Title
  
  口腔組織培養学会誌 11(1)
  
  Pages: 19-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13557174
[Journal Article] Cell motility of oral squamous cell carcinoma.2002
- Author(s)
  Niinaka F, Arai N, Yamaguchi S, Raz A, Amagasa T.
- Journal Title
  
  Jpn.J.Tissue Cult.Dent.Res. 11(1)
  
  Pages: 19-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557174
[Journal Article] Vimentin expression in oral squamous carcinoma cells induced by Autocrine Motility Factor (AMF).2001
- Author(s)
  Niinaka F, Arai N, Yamaguchi S, Amagasa T.
- Journal Title
  
  Jpn.J.Tissue Cult.Dent.Res. 10(2)
  
  Pages: 35-43
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557174
[Journal Article] 口腔扁平上皮癌細胞におけるAutocrine motility factor(AMF)によるVimentin 発現誘導2001
- Author(s)
  新中康史, 新井直也, 山口聰, 他
- Journal Title
  
  口腔組織培養学会誌 10(2)
  
  Pages: 35-43
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13557174
[Presentation] 口腔骨肉腫細胞におけるphosphodiesterase2の細胞増殖と運動能への役割2020
- Author(s)
  村田琢), 清水香澄, 黒原一人, 留奥曜, 小泉岳, 新井直也
- Organizer
  口腔組織培養学会誌
- Data Source
  KAKENHI-PROJECT-19K10285
[Presentation] アルカリ環境におけるリン酸カルシウム塩の形成とzoredronateの上皮細胞毒性の増強2013
- Author(s)
  新井直也、井上さやか、冨原　圭、平識　亘、古川健一朗、野口　誠
- Organizer
  第58回日本口腔外科学会総会・学術大会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-24592983
[Presentation] Characterization of regulatory T cells (Tregs) in oral cancer2012
- Author(s)
  Tomihara K, Inoue S, Takei R, Imaue S, Arai N, Noguchi M
- Organizer
  10^<th> Asian Congress on Oral and Maxillofacial Surgery
- Place of Presentation
  Bali
- Data Source
  KAKENHI-PROJECT-23592957
[Presentation] Characterization of regulatory T cells(Tregs) in oral cancer.2012
- Author(s)
  冨原　圭、井上さやか、武井理恵、今上修一、新井直也、野口　誠
- Organizer
  10th Asian Congress on Oral and Maxillofacial Surgery
- Place of Presentation
  Bali, Indonesia
- Data Source
  KAKENHI-PROJECT-23592957
[Presentation] Analysis of the characterization of regulatory T cells in a mouse model for oral cancer2011
- Author(s)
  Tomihara K., Inoue S., Arai N., Noguchi M.
- Organizer
  70th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Nagoya
- Data Source
  KAKENHI-PROJECT-23592957
[Presentation] Effect of clinically-relevant concentrations of zoledronate acid on cultured humanoral cancer cells2011
- Author(s)
  Inoue S., Arai N., Tomihara K., Noguchi M.
- Organizer
  70th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Nagoya
- Data Source
  KAKENHI-PROJECT-23592957
[Presentation] 口腔扁平上皮癌細胞株における低濃度ビスフォスフォの抗腫瘍効果2011
- Author(s)
  井上さやか、新井直也、野口誠
- Organizer
  第65回日本口腔科学会学術集会
- Place of Presentation
  東京
- Year and Date
  2011-04-22
- Data Source
  KAKENHI-PROJECT-20592356
[Presentation] A strategy for organ preservation in treating of locally advanced oral cancer.2010
- Author(s)
  Noguchi M., Tsuno H., Imaue S., Ohura T., Inoue S., Arai N.
- Organizer
  9^<th> Asian congress onoral & maxillofacial surgery Kuala Lumpur
- Place of Presentation
  Malaysia
- Year and Date
  2010-10-26
- Data Source
  KAKENHI-PROJECT-20592356
[Presentation] 上顎前歯部に発生した角化襄胞性歯原性腫瘍の1例2008
- Author(s)
  井上さやか、朽名智彦、金佳美、能登久美子、井上秀一、新井直也、野口誠
- Organizer
  第33回日本口腔外科学会中部地方会
- Place of Presentation
  於岐阜
- Year and Date
  2008-05-24
- Data Source
  KAKENHI-PROJECT-20592356
[Presentation] Synergistic effects of bisphosphonate and calcium on viability of epithelial cells; An in vitro study
- Author(s)
  Arai N, Inoue S, Tomihara K, Tsuno H, Noguchi M
- Organizer
  アジア口腔顎顔面外科学会
- Place of Presentation
  インドネシア　バリ
- Data Source
  KAKENHI-PROJECT-24592983
[Presentation] ビスフォスフォネートの上皮細胞毒性とカルシウムの相乗作用
- Author(s)
  新井直也、井上さやか、冨原圭、津野宏彰、野口誠
- Organizer
  日本口腔外科学会（総会）
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24592983

1. NOGUCHI Makoto (50208328)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
2. TOMIHARA Kei (70404738)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
3. YAMAGUCHI Satoshi (00280628)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. YAMADA Schumpei (60302890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NIINAKA Yasufumi (80361715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. Kurohara Kazuto (90401364)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Arai Naoya 新井 直也

新井 直也 アライ ナオヤ

ARAI Naoya 新井 直也

Research Projects

Research Products

Co-Researchers

Analysis of the mucous membrane damaging effect of the complex of bisphosphonate and calcium salt

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

An in vitro study on the role of calcium in bisphosphonate-related osteonecrosis of jaw.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A novel strategy against bone invasion of oral cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Type of bone invasion in human or al squamous cell carcinoma and its mechanisms ; application for molecular diagnosis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Gene therapy for oral cancer by cell cycle regulators and tumor vaccine genetically mokified to secrete cytokines.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Gemcitabine chemotherapy induces phenotypic alterations of tumor cells that facilitate antitumor T cell responses in a mouse model of oral cancer2014

Author(s)

Journal Title

Data Source

[Journal Article] CD44 and SSEA-4 positive cells in an oral cancer cell line HSC-4 possess cancer stem-like cell characteristics2013

Author(s)

Journal Title

Data Source

[Journal Article] In vitro synergistic effects of zoledronic acid and calcium on viability of human epithelial cells2013

Author(s)

Journal Title

Data Source

[Journal Article] Heparin induces apoptosis through suppression of AKt in oral squamous cell carcinoma cells.2009

Author(s)

Journal Title

Data Source

[Journal Article] 口腔扁平上皮癌細胞の遊走様式についての研究2002

Author(s)

Journal Title

Description

Data Source

[Journal Article] Cell motility of oral squamous cell carcinoma.2002

Author(s)

Journal Title

Description

Data Source

[Journal Article] Vimentin expression in oral squamous carcinoma cells induced by Autocrine Motility Factor (AMF).2001

Author(s)

Journal Title

Description

Data Source

[Journal Article] 口腔扁平上皮癌細胞におけるAutocrine motility factor(AMF)によるVimentin 発現誘導2001

Author(s)

Journal Title

Description

Data Source

[Presentation] 口腔骨肉腫細胞におけるphosphodiesterase2の細胞増殖と運動能への役割2020

Author(s)

Organizer

Data Source

[Presentation] アルカリ環境におけるリン酸カルシウム塩の形成とzoredronateの上皮細胞毒性の増強2013

Author(s)

Organizer

Place of Presentation

Arai Naoya 新井直也

新井直也アライナオヤ

ARAI Naoya 新井直也