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Murai Hiroyuki  村井 弘之

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… Alternative Names

MURAI Hiroyuki  村井 弘之

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Researcher Number 80325464
Other IDs
External Links
Affiliation (Current) 2025: 国際医療福祉大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2017 – 2022: 国際医療福祉大学, 医学部, 主任教授
2017: 九州大学, 大学病院, 講師
2016: 九州大学, 医学研究院, 教授
2015: 九州大学, 大学病院, 准教授
2006: Kyushu University, Department of Neurology, Assistant Professor, 大学病院, 講師 … More
2003 – 2006: Kyushu University, Department of Neurology, Clinical Instructor, 大学病院, 助手
2004: Kyushu University, University Hospital, Assistant professor, 大学病院, 講師
2003: 九州大学, 医学部付属病院, 助手
2002 – 2003: University Hospial, Instructor, 医学部附属病院, 助手
2001: Dep. of Neurology, Kyushu University, Res. Ass., 大学院・医学(系)研究科(研究院), 助手
2001: Department of Neurology, Kyushu University, Clinical Instructor, 大学院・医学研究院, 助手
2000 – 2001: 九州大学, 医学部・附属病院, 助手 Less
Review Section/Research Field
Principal Investigator
Neurology / Neurology
Except Principal Investigator
Neurology / Neurology / Neurosurgery
Keywords
Principal Investigator
Th1 / 重症筋無力症 / メッセンジャーRNA / リスクファクター / 臨床疫学 / クリーゼ / proteomic analysis / two-dimension immunoblot / axonal injury / autoantibody … More / multiple sclerosis / プロテオーム解析法 / 二次元免疫ブロット / 軸索障害 / 自己抗体 / 多発性硬化症 / allergic conjunctivitis / intracellular cytokine / autoimmune disease / Th2 balance / apoptosis / allergy / thymus / myasthenia gravis / アレルギー性結膜炎 / 細胞内サイトカイン / 自己免疫疾患 / Th2バランス / アポトーシス / アレルギー / 胸腺 … More
Except Principal Investigator
多発性硬化症 / SEREX / HLAクラスII / HSP105 / 視神経脊髄型 / NMO / MRI / LESCL / multiple sclerosis / hsp105 / HLA-class II / DPB1^*0501 / 視神経脊髄型多発性硬化症 / 気道アレルギー / t-PA / ICT / 治療効率化 / 脳梗塞急性期治療プロトコル / Door-to-needle time / t-PA / 脳梗塞診療支援システム / 血栓溶解療法 / 診療支援システム / tPA / 急性期脳梗塞 / ICT支援 / 脳卒中診療プロトコル / 脳血管内治療 / rt-PA療法 / 脳梗塞急性期治療 / 抗アセチルコリン受容体抗体 / MIR抗体 / AChR抗体 / アセチルコリン受容体 / MIR / 主要免疫原性領域 / 重症筋無力症 / Brazil / China / optico-spinal MS / EAE / HLA / ブラジル / 中国 / 視神経脊髄型MS / transgenic mouse / HLA class II / opticospinal / トランスジェニックマウス / Persistent infection / Demyelination / L* / Multiple sclerosis / Theiler's murine encephalomyelitis virus / 持続感染 / 脱髄 / L^* / キメラ / 実験的アレルギー脳炎 / タイラーウイルス / Autoantibody / Opticospinal form / Multiple Sclerosis / SEREX法 / 自己抗原 / HLA-クラスII / 自己抗体 / optico-spinal form of multiple sclerosis / CD8 T cells / eosinophil cationic protein / eosinophils / airway allergy / atopic dermatitis / atopic myelitis / ECP / EDN / RANTES / eotaxin / Th2 / 運動ニューロン / CD8陽性T細胞 / Eosinophil cationic protein / 好酸球 / アトピー性皮膚炎 / アトピー性脊髄炎 / 血漿型PAF-AH / 遺伝子多型 / ミエロパチー / 脊髄炎 / アトピー素因 / 血漿交換 / 抗ガングリオシド抗体 / 抗神経抗体 / 低親和性IgE受容体(CD23) / 平山病 / 運動ニューロン傷害 / アトピー Less
  • Research Projects

    (12 results)
  • Research Products

    (55 results)
  • Co-Researchers

    (26 People)
  •  Attempt to elucidate the pathological mechanisms of myasthenic crisisPrincipal Investigator

    • Principal Investigator
      Murai Hiroyuki
    • Project Period (FY)
      2017 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      International University of Health and Welfare
  •  A Study of improving treatment efficiency of acute stroke care by revamping acute phase protocol

    • Principal Investigator
      Matsumoto Shoji
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      Fujita Health University
      Kyushu University
  •  Antibodies against the main immunogenic region of the acetylcholine receptor correlate with disease severity in myasthenia gravis; Multicenter Study

    • Principal Investigator
      Narita Tomoko
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagasaki Kawatana Medical Center
  •  HLA class II polymorphism and worldwide susceptibility to optico-spinal multiple sclerosis.

    • Principal Investigator
      MINOHARA Motozumi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      KYUSHU UNIVERSITY
  •  Proteomic analysis of axonal injury in multiple sclerosisPrincipal Investigator

    • Principal Investigator
      MURAI Hiroyuki
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      KYUSHU UNIVERSITY
  •  アトピー素因を伴う脊髄炎・ミエロパチーにおける疾患感受性遺伝子の検索

    • Principal Investigator
      吉良 潤一
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Kyushu University
  •  Development of an animal model of opticospinal form of multiple sclerosis using the HLA-DP5 transgenic mice.

    • Principal Investigator
      KIRA Jun-ichi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Kyushu University
  •  STUDY OF ALLERGIC REACTION IN PATHOGENESIS OF MYASTHENIA GRAVISPrincipal Investigator

    • Principal Investigator
      MURAI Hiroyuki
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      KYUSHU UNIVERSITY
  •  アトピー性疾患に伴う脊髄前角運動ニューロン傷害の発生機序に関する分子免疫学的研究

    • Principal Investigator
      KIRA Jun-ichi
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Kyushu University
  •  MOLECULAR AND PATHOLOGICAL ANALYSIS OF SPINAL CORD EOSINOPHILIC LESIONS IN ATOPIC MYELITIS

    • Principal Investigator
      KIRA Jun-ichi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      KYUSHU UNIVERSITY
  •  Identification of a specific autoantigen in opticospinal form of multiple sclerosis based on the HLA-DPB1 binding motif

    • Principal Investigator
      KIRA Jun-ichi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Kyushu University
  •  Research for the mechanisms of continuous infection and demyelination of Theiler's murine encephalomyelitis virus

    • Principal Investigator
      KIKUCHI Hitoshi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      KYUSHU UNIVERSITY

All 2023 2022 2021 2020 2019 2018 2017 2005 2004 Other

All Journal Article Presentation Other

  • [Journal Article] Patient-reported burden of myasthenia gravis: baseline results of the international prospective, observational, longitudinal real-world digital study MyRealWorld-MG.2023

    • Author(s)
      Dewilde S, Philips G, Paci S, Beauchamp J, Chiroli S, Quinn C, Day L, Larkin M, Palace J, Berrih-Aknin S, Claeys KG, Muppidi S, Mantegazza R, Sacca F, Meisel A, Bassez G, Murai H, Janssen M.
    • Journal Title

      BMJ Open

      Volume: 13 Issue: 1 Pages: e066445-e066445

    • DOI

      10.1136/bmjopen-2022-066445

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Journal Article] Advances and ongoing research in the treatment of autoimmune neuromuscular junction disorders2022

    • Author(s)
      Verschuuren J, Palace J, Murai H, Tannemaat M, Kaminski H, Bril V
    • Journal Title

      Lancet Neurol

      Volume: 21 Issue: 2 Pages: 189-202

    • DOI

      10.1016/s1474-4422(21)00463-4

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Journal Article] Safety and effectiveness of eculizumab in Japanese patients with generalized myasthenia gravis: Analysis of 1-year postmarketing surveillance.2022

    • Author(s)
      Murai H, Suzuki S, Fukamizu Y, Osawa T, Kikui H, Utsugisawa K:
    • Journal Title

      Clin Exp Neuroimmunol

      Volume: 13 Issue: 4 Pages: 280-289

    • DOI

      10.1111/cen3.12716

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Journal Article] Safety and effectiveness of eculizumab in Japanese patients with generalized myasthenia gravis: Interim analysis of post-marketing surveillance2021

    • Author(s)
      Murai H, Suzuki S, Hasebe M, Fukamizu Y, Rodrigues E, Utsugisawa K
    • Journal Title

      Ther Adv Neurol Disord

      Volume: 14

    • DOI

      10.1177/17562864211001995

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Journal Article] International Consensus Guidance for Management of Myasthenia Gravis: 2020 Update2021

    • Author(s)
      Narayanaswami P, Sanders DB, Wolfe GI, Benatar M, Cea G, Evoli A, Gilhus NE, Illa I, Kuntz N, Massey JM, Melms A, Murai H, Nicolle M, Palace J, Richman DP, Verschuuren J
    • Journal Title

      Neurology

      Volume: 96 Issue: 3 Pages: 114-122

    • DOI

      10.1212/wnl.0000000000011124

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Journal Article] The patient-reported impact of myasthenia gravis in the real world: protocol for a digital observational study (MyRealWorld MG)2021

    • Author(s)
      Berrih-Aknin S, Claeys KG, Law N, Mantegazza R, Murai H, Sacca F, Dewilde S, Janssen MF, Bagshaw E, Kousoulakou H, Larkin M, Beauchamp J, Leighton T, Paci S
    • Journal Title

      BMJ Open

      Volume: 11 Issue: 7 Pages: e048198-e048198

    • DOI

      10.1136/bmjopen-2020-048198

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Journal Article] Zilucoplan: an investigational complement C5 inhibitor for the treatment of acetylcholine receptor autoantibody- positive generalized myasthenia gravis2021

    • Author(s)
      Howard JF, Vissing J, Gilhus NE, Leite MI, Utsugisawa K, Duda PW, Farzaneh-Far R, Murai H, Wiendl H
    • Journal Title

      Expert Opin Investig Drugs

      Volume: 30 Issue: 5 Pages: 483-493

    • DOI

      10.1080/13543784.2021.1897567

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Journal Article] Efficacy, Safety, and Tolerability of Efgartigimod in Patients with Generalized Myasthenia Gravis (gMG): Analysis of the Randomized Phase 3 ADAPT Study2021

    • Author(s)
      Howard JF, Bril V, Vu T, Karam C, Peric S, Margania T, Murai H, Bilinska M, Shakarishvili R, Smilowski M, Guglietta A, Ulrichts P, Vangeneugden T, Utsugisawa K, Verschuuren J, Mantegazza R, ADAPT Investigator Study Group
    • Journal Title

      Lancet Neurol

      Volume: 20 Issue: 7 Pages: 526-536

    • DOI

      10.1016/s1474-4422(21)00159-9

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Journal Article] Suitable indications of eculizumab for patients with refractory generalized myasthenia gravis2020

    • Author(s)
      Oyama M, Okada K, Masuda M, Shimizu Y, Yokoyama K, Uzawa A, Kawaguchi N, Ikeguchi R, Hoshino Y, Hatano T, Ozawa Y, Nakahara J, Aizawa H, Kitagawa K, Hattori N, Kuwabara S, Murai H, Suzuki S
    • Journal Title

      Therapeutic Advances in Neurological Disorders

      Volume: 13 Pages: 1-9

    • DOI

      10.1177/1756286420904207

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09780, KAKENHI-PROJECT-18K07537
  • [Journal Article] Response to eculizumab in patients with myasthenia gravis recently treated with chronic IVIg: a subgroup analysis of REGAIN and its open-label extension study2020

    • Author(s)
      Jacob S, Murai H, Utsugisawa K, Nowak RJ, Wiendl H, Fujita KP, O’Brien F, Howard JF
    • Journal Title

      Ther Adv Neurol Disord

      Volume: 13 Pages: 1-8

    • DOI

      10.1177/1756286420911784

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Journal Article] Clinical burden and healthcare resource utilization associated with myasthenia gravis: assessments from a Japanese claims database2019

    • Author(s)
      Murai H, Hasebe M, Murata A, Utsugisawa K
    • Journal Title

      Clin Exp Neuroimmunol

      Volume: 10 Issue: 1 Pages: 61-68

    • DOI

      10.1111/cen3.12495

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Journal Article] Long-term safety and efficacy of eculizumab in generalized myasthenia gravis.2019

    • Author(s)
      Muppidi S, Utsugisawa K, Benatar M, Murai H, Barohn RJ, Illa I, Jacob S, Vissing J, Burns TM, Kissel JT, Nowak RJ, Andersen H, Casasnovas C, de Bleecker JL, Vu TH, Mantegazza R, O'Brien FL, Wang JJ, Fujita KP, Howard JF Jr; Regain
    • Journal Title

      Muscle Nerve.

      Volume: - Issue: 1 Pages: 14-24

    • DOI

      10.1002/mus.26447

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05279, KAKENHI-PROJECT-17K09780
  • [Journal Article] Long-term efficacy and safety of eculizumab in Japanese patients with generalized myasthenia gravis: A subgroup analysis of the REGAIN open-label extension study2019

    • Author(s)
      Murai H, Uzawa A, Suzuki Y, Imai T, Shiraishi H, Suzuki H, Okumura M, O’Brien F, Wang JJ, Fujita KP, Utsugisawa K
    • Journal Title

      Journal of the Neurological Sciences

      Volume: 407 Pages: 116419-116419

    • DOI

      10.1016/j.jns.2019.08.004

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Journal Article] Oral corticosteroid dosing regimen and long-term prognosis in generalised myasthenia gravis: a multicentre cross-sectional study in Japan2018

    • Author(s)
      Imai Tomihiro、Utsugisawa Kimiaki、Murai Hiroyuki、Tsuda Emiko、Nagane Yuriko、Suzuki Yasushi、Minami Naoya、Uzawa Akiyuki、Kawaguchi Naoki、Masuda Masayuki、Konno Shingo、Suzuki Hidekazu、Akaishi Tetsuya、Aoki Masashi
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: in press Issue: 5 Pages: 513-517

    • DOI

      10.1136/jnnp-2017-316625

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09691, KAKENHI-PROJECT-17K09780
  • [Journal Article] Rationale for the clinical guidelines for myasthenia gravis in Japan2018

    • Author(s)
      Murai H, Utsugisawa K, Nagane Y, Suzuki S, Imai T, Motomura M
    • Journal Title

      Annals of the New York Academy of Sciences

      Volume: 1413 Issue: 1 Pages: 35-40

    • DOI

      10.1111/nyas.13544

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K09780, KAKENHI-PROJECT-17K09787
  • [Journal Article] Intrathecal activation of the IL-17/IL-8 axis tin opticospinal multiple sclerosis2005

    • Author(s)
      Ishizu T, Osoegawa M, Mei F, Kikuhi H, Tanaka M, Takakura Y, Minohara M, Murai H, Mihara F, Taniwaki T, Kira J
    • Journal Title

      Brain 128

      Pages: 988-1002

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590894
  • [Journal Article] Intrathecal activation of the IL-17/IL-8 axis in opticospinal multiple sclerosis.2005

    • Author(s)
      Ishizu T, Osoegawa M, Mei F, Kikuchi H, Tanaka M, Takakura Y, Minohara M, Murai H, Mihara F, Taniwaki T, Kira J
    • Journal Title

      Brain 128

      Pages: 988-1002

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590894
  • [Journal Article] Intrathecal activation of the IL-17/IL-8 axis in opticospinal multiple sclerosis2005

    • Author(s)
      Ishizu T, Osoegawa M, Mei F, Kikuchi H, Tanaka M, Takakura Y, Minohara M, Murai H, Mihara F, Taniwaki T, Kira J
    • Journal Title

      Brain (in press)

    • Data Source
      KAKENHI-PROJECT-15590894
  • [Journal Article] Th1 shift in CIDP versus Th2 shift in vasculitic neuropathy in CSE2005

    • Author(s)
      Mei F, Ishizu T, Murai H, Osoegawa M, Minohara M, Zhang K, Kira J
    • Journal Title

      J Neurol Sci 228

      Pages: 75-85

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590894
  • [Journal Article] Th1 shift in CIDP versus Th2 shift in vasculitic neuropathy in CSF.2005

    • Author(s)
      Mei F, Ishizu T, Murai H, Osoegawa M, Minohara M, Zhang K, Kira J
    • Journal Title

      J Neurol Sci 228

      Pages: 75-85

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590894
  • [Journal Article] Th1 shift in CIDP versus Th2 shift in vasculitic neuropathy in CSF2005

    • Author(s)
      Mei F, Ishizu T, Murai H, Osoegawa M, Minohara M, Zhang K, Kira J
    • Journal Title

      J Neurol Sci 228

      Pages: 75-85

    • Data Source
      KAKENHI-PROJECT-15590894
  • [Journal Article] Platelet-activating factor receptor gene polymorphism in Japanese patients with multiple sclerosis2005

    • Author(s)
      Osoegawa M, Miyagishi R, Ochi H, Nakamura I, Niino M, Kikuchi S, Murai H, Fukazawa T, Minohara M, Tashiro K, Kira J
    • Journal Title

      J Neuroimmunol 161

      Pages: 195-8

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590894
  • [Journal Article] Effect of immunotherapy in myelitis with atopic diathesis.2004

    • Author(s)
      Murai H, Arahata H, Osoegawa M, Ochi H, Minohara M, Taniwaki T, Tobimatsu S, Mihara F, Tsuruta Y, Inaba S, Kira J
    • Journal Title

      J Neurol Sci 227

      Pages: 39-47

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590894
  • [Journal Article] effect of immunotherapy in myelitis with atopic diathesis2004

    • Author(s)
      Murai H, Arahata H, Osoegawa M, Ochi H, Minohara M, Taniwaki T, Tobimatsu S, Mihara F, Tsuruta Y, Inaba S, Kira J
    • Journal Title

      J Neurol Sci 227

      Pages: 39-47

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590894
  • [Journal Article] Effect of immunotherapy in myelitis with atopic diathesis2004

    • Author(s)
      Murai H, Arahata H, Osoegawa M, Ochi H, Minohara M, Taniwaki T, Tobimatsu S, Mihara F, Tsuruta Y, Inaba S, Kira J
    • Journal Title

      J Neurol Sci 227

      Pages: 39-47

    • Data Source
      KAKENHI-PROJECT-15590894
  • [Journal Article] High frequency of allergic conjunctivitis in myasthenia gravis without thymoma2004

    • Author(s)
      Murai H, Osoegawa M, Ochi H, Kira J
    • Journal Title

      J Neurol Sci 225

      Pages: 27-31

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590894
  • [Journal Article] Platelet-activating factor acetylhydrolase gene polymorphism and its activity in Japanese patients with multiple sclerosis.2004

    • Author(s)
      Osoegawa M, Niino M, Ochi H, Kikuchi S, Murai H, Fukazawa T, Minohara M, Tashiro K, Kira J
    • Journal Title

      J Neuroimmunol 150

      Pages: 150-156

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590894
  • [Presentation] LUMINESCE: Phase 3 study of satralizumab, a therapeutic recycling antibody targeting the IL-6 receptor, in patients with generalised myasthenia gravis.2022

    • Author(s)
      Kaminski H, Zhao C, Meyer zu Horste G, O’Connor KC, Klingelschmitt G, Krumova P, Bolt S, Vodopivec I, Lennon-Chrimes S, Murai H:
    • Organizer
      27th Annual Congress of the World Muscle Society
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] Long-Term Safety and Efficacy of Efgartigimod in Patients With Generalized Myasthenia Gravis: Interim Results of the ADAPT+ Study2022

    • Author(s)
      Meisel A, Bril V, Vu T, Karam C, Peric S, De Bleecker JL, Murai H, Beydoun S, Pasnoor M, Guglietta A, Ulrichts P, T’joen C, Utsugisawa K, Verschuuren J, Mantegazza R, Howard JF:
    • Organizer
      8th Congress of the European Academy of Neurology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] Efficacy of Efgartigimod in Generalized Myasthenia Gravis: Myasthenia Gravis Composite Score Analysis From ADAPT.2022

    • Author(s)
      De Bleecker JL, Meisel A, Howard JF, Vu T, Bril V, Ulrichts P, Guglietta A, T’joen C, Murai H, Utsugisawa K, Mantegazza R:
    • Organizer
      17th International Congress on Neuromuscular Diseases
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] Real-world effectiveness of eculizumab in generalized myasthenia gravis in Japan: 1-year post-marketing surveillance data2022

    • Author(s)
      Murai H, Suzuki S, Fukamizu Y, Osawa T, Kikui H, Utsugisawa K:
    • Organizer
      第63回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] Long-Term Safety, Tolerability, and Efficacy of Efgartigimod in Patients With Generalized Myasthenia Gravis: Interim Results of the ADAPT+ Study.2022

    • Author(s)
      Howard JF, Bril V, Vu T, Karam C, Peric S, De Bleecker JL, Murai H, Meisel A, Beydoun S, Pasnoor M, Guglietta A, Ulrichts P, T’joen C, Utsugisawa K, Verschuuren J, Mantegazza R:
    • Organizer
      74th Annual Meeting of American Academy of Neurology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] Real-world experience with refractory generalized myasthenia gravis2021

    • Author(s)
      Murai H
    • Organizer
      16th International Congress on Neuromuscular Diseases
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] REAL-WORLD PATIENT-REPORTED IMPACT OF MYASTHENIA GRAVIS: INITIAL DATA FROM THE MYREALWORLD MG STUDY2021

    • Author(s)
      Murai H, Claeys K, Friconneau M, Larkin M, Shao J
    • Organizer
      第39回日本神経治療学会
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] Analysis of Efgartigimod Efficacy Across Patient Populations and Myasthenia Gravis Specific Scales2021

    • Author(s)
      Murai H, Bril V, Vu T, Karam C, Peric S, Imai T, Takahashi M, Uzawa A, Guglietta A, Ulrichts P, Vangeneugden T, Utsugisawa K, Mantegazza R, Howard J
    • Organizer
      第62回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] 抗補体薬ソリリスの位置づけ2021

    • Author(s)
      村井弘之
    • Organizer
      第33回日本神経免疫学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] エクリズマブ投与時の全身型重症筋無力症患者の病態生理特性に関する多施設共同臨床研究(中間解析)2021

    • Author(s)
      村井弘之, 鈴木靖士, 永田栄一郎, 望月秀樹, 横山和正, 大崎康史, 関口兼司, 玉岡晃, 中嶋秀人, 丹羽淳一,野村恭一, 阪田麻友美, 増田眞之, 南尚哉, 岡村和美, 深水裕二, 小原崇史, 鈴木重明
    • Organizer
      第33回日本神経免疫学会
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] COVID-19時代におけるMGのマネージメント2021

    • Author(s)
      村井弘之
    • Organizer
      第33回日本神経免疫学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] ADAPT: A Randomized Phase 3 Study of the FcRn antagonist, Efgartigimod, in Myasthenia Gravis2020

    • Author(s)
      Howard JF, Vu T, Bril V, De Bleecker J, Verschuuren J, Mantegazza R, Meisel A, Peric S, de Haard H, Parys W, Guglietta A, Ulrichts P, Murai H.
    • Organizer
      AANEM 2020 Annual Meeting (American Association of Neuromuscular & Electrodiagnostic Medicine)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] 日本におけるエクリズマブの全身型重症筋無力症に関する製造販売後調査の中間解析2020

    • Author(s)
      村井弘之、鈴木重明、長谷部美紀、深水裕二、ロドリゲスエマ、槍澤公明
    • Organizer
      第61回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] 難治性重症筋無力症に対するエクリズマブの適応2020

    • Author(s)
      大山宗徳、岡田健佑、増田真之、清水優子、横山和正、川口直樹、鵜沢顕之、中原仁、村井弘之、鈴木重明
    • Organizer
      第117回日本内科学会総会
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] Safety and effectiveness of eculizumab for patients with generalized myasthenia gravis in Japan: Interim analysis of post-marketing surveillance2020

    • Author(s)
      Murai H, Suzuki S, Hasebe M, Fukamizu Y, Rodriguez E, Utsugisawa K
    • Organizer
      The 6th European Academy of Neurology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] 重症筋無力症の新しい分類と治療戦略2019

    • Author(s)
      村井弘之
    • Organizer
      第37回日本神経治療学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] Response to eculizumab in patients with myasthenia gravis recently treated with chronic intravenous immunoglobulin2019

    • Author(s)
      Genge A, Jacob S, Murai H, Utsugisawa K, Nowak RJ, Wiendl H, Fujita KP, O’Brien F, Howard JF
    • Organizer
      The 54th Canadian Neurological Sciences Federation Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] 重症筋無力症:新時代の治療戦略2019

    • Author(s)
      村井弘之
    • Organizer
      第60回日本神経病理学会総会学術研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] Relieving the burden of myasthenia gravis: eculizumab reduces exacerbation, hospitalization and rescue therapy rates2019

    • Author(s)
      Siddiqi Z, Howard JF, Jacob S, Guptill JT, Meisel A, Wiendl H, Murai H, Utsugisawa K, Nowak RJ, Fujita KP, O’Brien F, Patra K, Muppidi S
    • Organizer
      The 54th Canadian Neurological Sciences Federation Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] 重症筋無力症に対するエクリズマブ治療:これまでにわかったこと、わからないこと2019

    • Author(s)
      村井弘之
    • Organizer
      第60回日本神経学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] Response to eculizumab in patients with AChR+ refractory myasthenia gravis recently treated with chronic IVIg2018

    • Author(s)
      Jacob S, Murai H, Utsugisawa K, Nowak RJ, Wiendl H, Fujita KP, O’Brien F, Howard JF
    • Organizer
      The 15th International Congress on Neuromuscular Diseases
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] 重症筋無力症の診断から治療までの最前線2018

    • Author(s)
      村井弘之
    • Organizer
      第30回日本神経免疫学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] MGクリーゼに遭遇したら2018

    • Author(s)
      村井弘之
    • Organizer
      第36回日本神経治療学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] Open label extension trial of REGAIN to evaluate the safety and efficacy of eculizumab in patients from Japan with refractory generalized myasthenia gravis2017

    • Author(s)
      Murai H, Uzawa A, Suzuki Y, Imai T, Shiraishi H, Tsuda E, Suzuki H, Okumura M, Utsugisawa K
    • Organizer
      The 23rd World Congress of Neurology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] Updates on antibodies in myasthenia gravis2017

    • Author(s)
      Murai H
    • Organizer
      Asean Neurological Association Biennial Convention 2017
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09780
  • [Presentation] Early fast-acting treatment strategy against generalized myasthenia gravis2017

    • Author(s)
      Utsugisawa K, Nagane Y, Akaishi T, Suzuki Y, Imai T, Tsuda E, Minami N, Uzawa A, Kawaguchi N, Masuda M, Konno S, Suzuki H, Murai H, Aoki M
    • Organizer
      The 23rd World Congress of Neurology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09780
  • []

  • []

  • 1.  KIRA Jun-ichi (40183305)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 2.  OSOEGAWA Manabu (60380614)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  OCHI Hirofumi (20325442)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  NISHIMURA Yasuharu (10156119)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  KIKUCHI Hitoshi (60322765)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  Motomura Masakatsu (70244093)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 7.  MATSUSHITA Sho (50167649)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  FURUE Masutaka (70134583)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  ARAKI Norie (80253722)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  IKEZOE Koji (80343317)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  MINOHARA Motozumi (70398113)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  Narita Tomoko (20549373)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  Nakane Shunya (70398022)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  Matsuo Hidenori (20380975)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  Suzuki Shigeaki (50276242)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  Matsumoto Shoji (00570772)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  小山 裕司 (00319013)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  山田 猛 (50230462)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  槍澤 公明 (00244913)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  松下 拓也 (00533001)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  今井 富裕 (40231162)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 22.  呉 暁牧
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  呉 曉牧
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  UZAWA Akiyuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  槍沢 公明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 20 results
  • 26.  藤井 博匡
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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