Hatano Yutaka 波多野豊

… Alternative Names

HATANO Yutaka 波多野豊

波多野豊ハタノユタカ

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Researcher Number	80336263
Other IDs
Affiliation (Current)	2025: 大分大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2025: 大分大学, 医学部, 教授 2016 – 2023: 大分大学, 医学部, 教授 2013 – 2015: 大分大学, 医学部, 准教授 2014: 大分大学, 医学部, 教授 2008 – 2013: Oita University, 医学部, 講師 … More 2005 – 2006: 大分大, 医学部, 助手 2003 – 2004: 大分大学, 医学部, 助手 2002: 大分医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Dermatology / Basic Section 53050:Dermatology-related / Dermatology Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related / Basic Section 52010:General internal medicine-related / Basic Section 53050:Dermatology-related / Tumor diagnosis
Keywords	Principal Investigator 皮膚バリア機能 / アトピー性皮膚炎 / PPARα / 表皮角化細胞 / アレルギー性炎症 / Th2サイトカイン / セラミド / glucocerebrosidase / sphingomyelinase / 表皮 … More / 皮膚バリア回復能 / Typ2炎症 / 透過性バリア回復能 / 皮膚生理 / 生体分子 / 皮膚炎 / 皮膚バリア / ｍDia / skin barrier / mDia / ROCK / Rho / 皮膚炎症 / RANTES / TARC / フィラグリン / PPAR / ケモカイン / PPARalpha / デスモグレイン1 / コルネオデスモゾーム / 皮膚バリア修復 / 経皮的水分喪失量 / ヒト3次元皮膚培養モデル / TNF-α / IL-4 / IFN-γ / sphingomyelinas / ceramidase / Th1サイトカイン / Ceramidase … More Except Principal Investigator αリポ酸誘導体 / 細胞周期 / 抗がん剤 / 永久脱毛 / 抗がん剤誘発皮膚障害 / アピアランスケア / 抗酸化物質 / 化学療法 / 皮膚色素沈着 / 網羅的マイクロアレイ解析 / 創薬スクリーニング / 血管病変モデル / 管腔形成 / 血管内皮細胞 / iPS細胞 / 血管障害 / 全身性強皮症 / ＦＯＸＰ3 / ＣＴＬＡ-4 / 制御性Ｔ細胞 / ＥＧＦＲ阻害薬 / FOXP3 / EGFR阻害薬 / 癌 / がん / 制御性T細胞 / CTLA-4 / ざ瘡様皮疹 / 薬剤性皮膚障害 / 上皮成長因子受容体阻害薬 / 獲得耐性 Less

抗がん剤誘発皮膚色素沈着に対するαリポ酸誘導体を用いた治療開発
- Principal Investigator
  
  長澤由依子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Oita University
Development of Permanent Chemotherapy-Induced Alopecia Treatment Based on Cell Cycle Arresting Action of Alpha Lipoic Acid Derivatives
- Principal Investigator
  
  河野洋平
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Oita University
タイプ2炎症によるバリア回復低下：アトピー性皮膚炎におけるバリア異常の本質に迫るPrincipal Investigator
- Principal Investigator
  
  波多野豊
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Oita University
Establishment of a disease model for the vasculopathy in systemic sclerosis to develop a novel therapy
- Principal Investigator
  
  Goto Mizuki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Oita University
Involvement of Rho effector molecules on the homeostasis of stratum corneum barrierPrincipal Investigator
- Principal Investigator
  
  Hatano Yutaka
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Oita University
Depressed PPARalpha is involved in the pathogenesis of atopic dermatitisPrincipal Investigator
- Principal Investigator
  
  Hatano Yutaka
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Oita University
Are regulatory T cells related with resistance to Epidermal Growth Factor Receptor inhibitors?
- Principal Investigator
  
  WATANABE Koichiro
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor diagnosis
- Research Institution
  Oita University
Activation of PPARalpha abrogates the vicious cycle between cutaneous barrier dysfunction and allergic inflammationPrincipal Investigator
- Principal Investigator
  
  HATANO Yutaka
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Oita University
Th2 profile abrogates cutaneous barrier function. -New insight in the pathogenesis of atopic dermatitis-Principal Investigator
- Principal Investigator
  
  HATANO Yutaka
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Oita University
Th1,Th2サイトカインの皮膚バリア機能に及ぼす影響Principal Investigator
- Principal Investigator
  
  波多野豊
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Oita University
表皮におけるセラミド合成に対するTh1、Th2サイトカインの影響Principal Investigator
- Principal Investigator
  
  波多野豊
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  大分医科大学

All 2019 2017 2013 2012 2011 2010 2008 Other

All Journal Article Presentation

[Journal Article] Wy14643, an agonist for PPARα, down-regulates expression of TARC and RANTES in cultured human keratinocytes2017
- Author(s)
  Zhang W, Sakai T, Fujiwara S, Hatano Y
- Journal Title
  
  Experimental Dermatology
  
  Volume: 印刷中 Issue: 5 Pages: 457-459
- DOI
  10.1111/exd.13245
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461662, KAKENHI-PROJECT-25860958
[Journal Article] 皮膚バリア機能とその障害メカニズム2013
- Author(s)
  波多野豊
- Journal Title
  
  アレルギー・免疫
  
  Volume: 20(6) Pages: 836-844
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591649
[Journal Article] 表皮角化細胞が担う皮膚バリア機能とその障害メカニズム2013
- Author(s)
  波多野豊
- Journal Title
  
  西日皮
  
  Volume: 75(5) Pages: 399-405
- NAID
  130004475548
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591649
[Journal Article] Expressions of PPARs are directly influenced by permeability barrier abrogation and inflammatory cytokines and depressed PPARα modulates expressions of chemokines and epidermal differentiation-related molecules in keratinocytes.2013
- Author(s)
  Adachi Y, Hatano Y, Sakai T, Fujiwara S
- Journal Title
  
  Exp Dermatol
  
  Volume: 22 Issue: 9 Pages: 606-8
- DOI
  10.1111/exd.12208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591598, KAKENHI-PROJECT-23591649
[Journal Article] 皮膚バリア機能異常と炎症のクロストークの場としてのケラチノサイト2012
- Author(s)
  波多野豊
- Journal Title
  
  日皮会誌
  
  Volume: 122(13) Pages: 3277-3279
- Data Source
  KAKENHI-PROJECT-23591649
[Journal Article] Skin barrier abnormalities in atopic dermatitis : Cross talk with allergic inflammation2012
- Author(s)
  Hatano Y
- Journal Title
  
  J Skin Barrier Res
  
  Volume: 14(2) Pages: 13-19
- Data Source
  KAKENHI-PROJECT-23591649
[Journal Article] Efficacy of combined peroxisome proliferator-activated receptor-α ligand and glucocorticoid therapy in a murine model of atopic dermatitis2011
- Author(s)
  Hatano Y, Elias PM, Crumrine D, Feingold KR, Katagiri K, Fujiwara S
- Journal Title
  
  J Invest Dermatol
  
  Volume: 131 Issue: 9 Pages: 1845-52
- DOI
  10.1038/jid.2011.144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591649
[Journal Article] 皮膚のバリア機能とアトピー性皮膚炎-Th2・角層pHの重要性及びフィラグリン異常との関係-(総説)2011
- Author(s)
  波多野豊
- Journal Title
  
  J Environ Dermatol Cutan Allergol. 5巻1号
  
  Pages: 11-18
- Data Source
  KAKENHI-PROJECT-20591323
[Presentation] Differential therapeutic effects between mesoderm-like and neuroepithelium-like cells of mesenchymal stem cells derived from human iPS cells2019
- Author(s)
  Mizuki Goto, Takumi Era, Yutaka Hatano
- Organizer
  The 44th Annual Meeting of the Japanese Society for Investigative Dermatology
- Data Source
  KAKENHI-PROJECT-19K08796
[Presentation] アトピー性皮膚炎の病態と治療におけるリポセンサー2013
- Author(s)
  波多野豊
- Organizer
  第65回日本皮膚科学会西部支部学術大会
- Place of Presentation
  鹿児島市 (シンポジウム)
- Year and Date
  2013-11-10
- Data Source
  KAKENHI-PROJECT-23591649
[Presentation] 皮膚バリアと炎症のクロストークの場としてのケラチノサイト2012
- Author(s)
  波多野豊
- Organizer
  第111回日本皮膚科学会総会
- Place of Presentation
  京都市 (教育講演)
- Year and Date
  2012-06-02
- Data Source
  KAKENHI-PROJECT-23591649
[Presentation] Depressed PPARalpha accelerates a vicious cycle between allergic inflammation and barrier dysfunction2012
- Author(s)
  Adachi Y, Hatano Y, Sakai T, Fujiwara S
- Organizer
  The 37th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Okinawa
- Year and Date
  2012-12-08
- Data Source
  KAKENHI-PROJECT-23591649
[Presentation] Depressed PPAR accelerates a vicious cycle between allergic inflammation and barrier dysfunction2012
- Author(s)
  Yasuko Adachi, Yutaka Hatano, Takashi Sakai, Sakuhei Fujiwara
- Organizer
  The 37th annual meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Okinawa, Japan
- Data Source
  KAKENHI-PROJECT-23591649
[Presentation] Skin barrier abnormalities in atopic dermatitis~Cross talk with allergic inflammation ~2012
- Author(s)
  Hatano Y
- Organizer
  The 2012 Annual Meeting of the Korean Society for Skin Barrier Research
- Place of Presentation
  Seoul (招請講演)
- Year and Date
  2012-10-16
- Data Source
  KAKENHI-PROJECT-23591649
[Presentation] アトピー性皮膚炎の病態におけるperoxisome proliferators-activated receptor (PPAR)sの位置付けについて2011
- Author(s)
  足立育子　波多野豊　酒井貴史　藤原作平
- Organizer
  九州基礎皮膚科研究会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23591649
[Presentation] Peroxisome proliferators-activated receptor-alpha as a key molecule on the relationship between cutaneous barrier dysfunction and allergic inflammation.2010
- Author(s)
  Hatano Y, Adachi Y, Fujiwara S.
- Organizer
  The first annual meeting of Pan Asian-Pacific Skin Barrier Research Society
- Place of Presentation
  Dalian, China
- Data Source
  KAKENHI-PROJECT-20591323
[Presentation] IL-4 and IL-13 inhibit the recovery of cutaneous permea bility function by suppression of lamellar body secretion via STAT6 activation2008
- Author(s)
  Kurahashi R, Katagiri K, Hatano Y
- Organizer
  国際研究皮膚科学会2008
- Place of Presentation
  京都
- Year and Date
  2008-05-14
- Data Source
  KAKENHI-PROJECT-20591323
[Presentation] アトピー性皮膚炎の病態と治療におけるリポセンサー
- Author(s)
  波多野豊
- Organizer
  第65回日本皮膚科学会西部支部学術大会
- Place of Presentation
  鹿児島県民交流センター(鹿児島県鹿児島市）
- Invited
- Data Source
  KAKENHI-PROJECT-23591649

1. 長澤由依子 (00994716)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 大嶋佑介 (10586639)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 相場崇行 (10896012)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 平塚孝宏 (20600886)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 猪股雅史 (60315330)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 河野洋平 (90572008)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KATAGIRI Kazumoto (00204420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. WATANABE Koichiro (00468000)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SHIRAO Kuniaki (10467996)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. OOTSU Satoshi (80437920)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MORINAGA Ryotaro (50411640)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HIIRASHIMA Yoshinori (60418837)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. HISAMATSU Yasushi (00609670)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NISHIKAWA Kazuo (70636399)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KAWANO Sakura (40548137)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KOBAYASHI Takashi (30380520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. Goto Mizuki (70433050)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 藤原作平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hatano Yutaka 波多野 豊

HATANO Yutaka 波多野 豊

波多野 豊 ハタノ ユタカ

Research Projects

Research Products

Co-Researchers

抗がん剤誘発皮膚色素沈着に対するαリポ酸誘導体を用いた治療開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of Permanent Chemotherapy-Induced Alopecia Treatment Based on Cell Cycle Arresting Action of Alpha Lipoic Acid Derivatives

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

タイプ2炎症によるバリア回復低下：アトピー性皮膚炎におけるバリア異常の本質に迫るPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of a disease model for the vasculopathy in systemic sclerosis to develop a novel therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Involvement of Rho effector molecules on the homeostasis of stratum corneum barrierPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Depressed PPARalpha is involved in the pathogenesis of atopic dermatitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Are regulatory T cells related with resistance to Epidermal Growth Factor Receptor inhibitors?

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Activation of PPARalpha abrogates the vicious cycle between cutaneous barrier dysfunction and allergic inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Th2 profile abrogates cutaneous barrier function. -New insight in the pathogenesis of atopic dermatitis-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Th1,Th2サイトカインの皮膚バリア機能に及ぼす影響Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

表皮におけるセラミド合成に対するTh1、Th2サイトカインの影響Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Wy14643, an agonist for PPARα, down-regulates expression of TARC and RANTES in cultured human keratinocytes2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 皮膚バリア機能とその障害メカニズム2013

Author(s)

Journal Title

Hatano Yutaka 波多野豊

HATANO Yutaka 波多野豊

波多野豊ハタノユタカ