MATSUBARA Akihisa 松原明久

… Alternative Names

松原明久マツバラアキヒサ

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Researcher Number	80336685
Other IDs
Affiliation (based on the past Project Information) *help	2012: 名古屋市立大学, 大学院・医学研究科, 助教 2010: Nagoya City University, 医学(系)研究科(研究院), 助教 2007 – 2009: Nagoya City University, 大学院・医学研究科, 助教 2003: 名古屋市大, 医学(系)研究科(研究院), 助手 2002: 名古屋市立大学, 大学院・医学研究科, 助手
Review Section/Research Field	Principal Investigator Ophthalmology / Ophthalmology Except Principal Investigator Ophthalmology / Ophthalmology
Keywords	Principal Investigator 白血球 / アクリジンオレンジ / ラパマイシン / 虚血 / 綱膜微小循環 / アクリジン / TNF-alpha / 糖尿病ラット / 眼科学 / 加齢黄斑変性 / 網膜微小循環 / 過酸化脂質 … More Except Principal Investigator … More CNV / HUVEC / HGF / NK4 / ICAM-1 / 脈絡膜新生血管 / Drug delivery system / Biodegradable scleral implant / ARPE-19 / 肝細胞増殖因子阻害剤 / 強膜 / ベタメサゾン / リン酸ベタメサゾン / 生体非分解性高分子 / 生体分解性高分子 / ドラッグデリバリーシステム / 生体分解性強膜インプラント / pioglotazone hydrochloride / gliclazide / acridine orange / insulin / leukocyte-endothelial interaction / diabetic retinopathy / 網膜微小循環 / 白血球-血管内皮相互作用 / 網膜血管内皮細胞 / インスリン / 白血球 / アクリジンオレンジ / 塩酸ピオグリタゾン / グリクラジド / 接着分子 / 白血球-血管内皮細胞相互作用 / 糖尿病網膜症 / VEGF-A / 加齢黄斑変性症 / 脈絡膜新生血管(CNV) / RNA干渉(siRNA) / IFN-γ / クロロキン / TLR3 / RNA干渉（siRNA） / RNA 干渉(siRNA) / VEGF / アテロコラーゲン / 加齢黄斑変性 Less

Molecular mechanism on anti-angiogenic effect of siRNA in choroidal neovascularization
- Principal Investigator
  
  OGURA Yuichiro
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Nagoya City University
網膜虚血傷害の分子機構の解明と干渉RNAによる治療法の開発Principal Investigator
- Principal Investigator
  
  松原明久
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Nagoya City University
Investigation into the role of TNF-alpha in diabetic retinopathyPrincipal Investigator
- Principal Investigator
  
  MATSUBARA Akihisa
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Nagoya City University
加齢黄斑変性の病態における過酸化脂質の意義の解明―白血球循環動態評価からの検討Principal Investigator
- Principal Investigator
  
  松原明久
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Nagoya City University
The trial of treatment in choroidal neovascularization by the drug release system of NK4,inhibitors of hepatocyte growth factor
- Principal Investigator
  
  OKUDA Masatoshi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Nagoya City University
Studies on leukocyte-endothelial interactions in the pathogenesis of diabetic retinopathy
- Principal Investigator
  
  OGURA Yuichiro
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Nagoya City University

All 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] Aldose reductase inhibitor fidarestat attenuates leukocyte-endoth elial interactions in experimental diabetic rat retina in vivo.2010
- Author(s)
  Hattori T, Matsubara A, Taniguchi K, Ogura Y
- Journal Title
  
  Current Eye Research 35
  
  Pages: 146-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791701
[Journal Article] Pitavastatin attenuatesleukocyte-endothelial in teractions induced by ischemia-reperfusion injury in the rat retina.2009
- Author(s)
  Miyaki K, Matsubara A, Nishiwaki A, Tomida K, Morita H, Yoshida M, Ogura Y.
- Journal Title
  
  Curr Eye Res. 34(1)
  
  Pages: 10-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791279
[Journal Article] Effect of posterior sub-tenon administration of triamcinolone acetonide on leukocyte dynamics in rat retinal microcirculation after panretinal photocoagulation.2008
- Author(s)
  Mizuno D, Matsubara A, Ogura Y.
- Journal Title
  
  Invest Ophthalmol Vis Sci. 49
  
  Pages: 2127-2133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791279
[Journal Article] Photodynamic therapy induces caspase-dependent apoptosis in rat CNV model2007
- Author(s)
  松原明久
- Journal Title
  
  Investigative Ophthalmology & Visual Science 48
  
  Pages: 4741-4747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791279
[Presentation] 白血球動態からみた薬物と網膜微小循環2009
- Author(s)
  松原明久
- Organizer
  第26回日本眼循環学会
- Place of Presentation
  名古屋国際会議場(名古屋)
- Year and Date
  2009-12-06
- Data Source
  KAKENHI-PROJECT-21791701
[Presentation] 糖尿病ラットにおける網膜白血球集積に対するアルドース還元酵素阻害薬の抑制効果2008
- Author(s)
  服部知明、松原明久、谷口香織、小椋祐一郎
- Organizer
  第112回日本眼科学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19791279
[Presentation] Aldose reductase inhibitor attenuates leukocyte-endothelial interaction in experimental diabetic retina in vivo.2008
- Author(s)
  Hattori T, Matsubara A, Taniguchi K, Ogura Y
- Organizer
  Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO)
- Place of Presentation
  フォートローダーデール、米国
- Data Source
  KAKENHI-PROJECT-19791279
[Presentation] 糖尿病ラットにおける網膜白血球集積に対する腫瘍壊死因子(TNF-α)阻害薬の抑制効果2007
- Author(s)
  服部知明、松原明久、小椋祐一郎
- Organizer
  第111回日本眼科学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19791279

1. OGURA Yuichiro (70191963)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. YOSHIDA Munenori (60273447)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. MORITA Hiroshi (20363947)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. YASUKAWA Tsutomu (00324632)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NOZAKI Miho (00295601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 木村英也 (50252440)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 冨田一之 (40305537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. OKUDA Masatoshi (70336684)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MATSUBARA Akihisa 松原 明久

松原 明久 マツバラ アキヒサ

Research Projects

Research Products

Co-Researchers

Molecular mechanism on anti-angiogenic effect of siRNA in choroidal neovascularization

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

網膜虚血傷害の分子機構の解明と干渉RNAによる治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation into the role of TNF-alpha in diabetic retinopathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

加齢黄斑変性の病態における過酸化脂質の意義の解明―白血球循環動態評価からの検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The trial of treatment in choroidal neovascularization by the drug release system of NK4,inhibitors of hepatocyte growth factor

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on leukocyte-endothelial interactions in the pathogenesis of diabetic retinopathy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Aldose reductase inhibitor fidarestat attenuates leukocyte-endoth elial interactions in experimental diabetic rat retina in vivo.2010

Author(s)

Journal Title

Data Source

[Journal Article] Pitavastatin attenuatesleukocyte-endothelial in teractions induced by ischemia-reperfusion injury in the rat retina.2009

Author(s)

Journal Title

Data Source

[Journal Article] Effect of posterior sub-tenon administration of triamcinolone acetonide on leukocyte dynamics in rat retinal microcirculation after panretinal photocoagulation.2008

Author(s)

Journal Title

Data Source

[Journal Article] Photodynamic therapy induces caspase-dependent apoptosis in rat CNV model2007

Author(s)

Journal Title

Data Source

[Presentation] 白血球動態からみた薬物と網膜微小循環2009

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 糖尿病ラットにおける網膜白血球集積に対するアルドース還元酵素阻害薬の抑制効果2008

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Aldose reductase inhibitor attenuates leukocyte-endothelial interaction in experimental diabetic retina in vivo.2008

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 糖尿病ラットにおける網膜白血球集積に対する腫瘍壊死因子(TNF-α)阻害薬の抑制効果2007

Author(s)

Organizer

Place of Presentation

Data Source

MATSUBARA Akihisa 松原明久

松原明久マツバラアキヒサ