Ohba Shigeo 大場茂生

… Alternative Names

OHBA SHIGEO 大場茂生

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Researcher Number	80338061
Affiliation (Current)	2025: 藤田医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 藤田医科大学, 医学部, 准教授 2018 – 2023: 藤田医科大学, 医学部, 准教授 2016 – 2017: 藤田保健衛生大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Neurosurgery Except Principal Investigator Basic Section 56010:Neurosurgery-related / Basic Section 52040:Radiological sciences-related / Neurosurgery
Keywords	Principal Investigator がん代謝 / 神経膠腫 / IDH変異 / IDH / 網羅的代謝解析 / 網羅的遺伝子解析 / グリオーマ / iPS / グルタミン / アスパラギン … More / IDH1 / 代謝 / 腫瘍化 / 変異型IDH / mutant IDH / glioma … More Except Principal Investigator DNAミスマッチ修復 / 薬剤耐性 / DNAメチル化剤 / 膠芽腫 / 悪性神経膠腫 / G2チェックポイント / テモゾロミド / 神経膠腫 / ミスマッチ修復 / DNA相同組換え修復 / 人工知能 / 3次元化学交換飽和移動画像 / 脳腫瘍 / 髄膜腫 / 化学交換飽和移動イメージング / 磁気共鳴画像 / temozolomide / DNA修復機構 / シグナル伝達 / トランスレーショナルリサーチ / 薬剤反応性 / 癌 / 脳神経疾患 / 耐性 Less

グリオーマに対するテモゾロミドとALDH阻害剤併用療法の開発Principal Investigator
- Principal Investigator
  
  大場茂生
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Fujita Health University
Mechanisim of drug resistance and genomic instability associated with tumor progression of malignant glioma
- Principal Investigator
  
  廣瀬雄一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Fujita Health University
3次元化学交換飽和移動画像のAIによる新規再構成法と神経膠腫診断支援システム開発
- Principal Investigator
  
  村山和宏
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Fujita Health University
神経膠腫におけるがん代謝を標的とした治療法の開発Principal Investigator
- Principal Investigator
  
  大場茂生
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Fujita Health University
Association of drug resistance of human malignant glioma cells and DNA repair system
- Principal Investigator
  
  Hirose Yuichi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Fujita Health University
Elucidation of the mechanism of tumorigenesis and development of new treatments using iPS cell-derived mutant IDH glioma modelPrincipal Investigator
- Principal Investigator
  
  OHBA SHIGEO
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Fujita Health University
Mechanisim of acqired drug resistance by glioma
- Principal Investigator
  
  Hirose Yuichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Fujita Health University
Mutant IDH-induced iPS-derived glioma cellsPrincipal Investigator
- Principal Investigator
  
  OHBA SHIGEO
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Fujita Health University

All 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Three-Dimensional Gradient-Echo Based Amide Proton Transfer-Weighted Imaging of Brain Tumors: Comparison With Two-Dimensional Spin-Echo?Based Amide Proton Transfer-Weighted Imaging2023
- Author(s)
  Murayama Kazuhiro、Ohno Yoshiharu、Yui Masao、Yamamoto Kaori、Ikedo Masato、Ohba Shigeo、Hanamatsu Satomu、Iwase Akiyoshi、Ikeda Hirotaka、Hirose Yuichi、Toyama Hiroshi
- Journal Title
  
  Journal of Computer Assisted Tomography
  
  Volume: Publish Ahead of Print Issue: 3 Pages: 494-499
- DOI
  10.1097/rct.0000000000001432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07679, KAKENHI-PROJECT-22K09243
[Journal Article] Applied Fence-Post Techniques Using Deep Electrodes Instead of Catheters for Resection of Glioma Complicated with Frequent Epileptic Seizures: A Case Report2023
- Author(s)
  Nakae Shunsuke、Kumon Masanobu、Teranishi Takao、Ohba Shigeo、Hirose Yuichi
- Journal Title
  
  Brain Sciences
  
  Volume: 13 Issue: 3 Pages: 482-482
- DOI
  10.3390/brainsci13030482
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09243, KAKENHI-PROJECT-21K16621
[Journal Article] Three-Dimensional Amide Proton Transfer-Weighted Imaging for Differentiating between Glioblastoma, IDH-Wildtype and Primary Central Nervous System Lymphoma2023
- Author(s)
  Ohba Shigeo、Murayama Kazuhiro、Teranishi Takao、Kumon Masanobu、Nakae Shunsuke、Yui Masao、Yamamoto Kaori、Yamada Seiji、Abe Masato、Hasegawa Mitsuhiro、Hirose Yuichi
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 3 Pages: 952-952
- DOI
  10.3390/cancers15030952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07679, KAKENHI-PROJECT-22K09243
[Journal Article] Carotid Plaque Diagnosis With 3-Dimensional Computed Tomography Angiography: A Comparison With Magnetic Resonance Imaging?Based Plaque Diagnosis2023
- Author(s)
  Omi Tatsuo、Hayakawa Motoharu、Adachi Kazuhide、Ohba Shigeo、Sadato Akiyo、Hasebe Akiko、Ishihara Takuma、Nakahara Ichiro、Hirose Yuichi
- Journal Title
  
  Journal of Computer Assisted Tomography
  
  Volume: 47 Pages: 488-493
- DOI
  10.1097/rct.0000000000001416
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09243, KAKENHI-PROJECT-22H00190
[Journal Article] Intracranial phosphaturic mesenchymal tumors. A case report and review of literature2022
- Author(s)
  Kojima Daijiro、Ohba Shigeo、Abe Masato、Suzuki Atsushi、Horibe Seiji、Tateya Ichiro、Hasegawa Mitsuhiro、Hirose Yuichi
- Journal Title
  
  Neuropathology
  
  Volume: 42 Issue: 5 Pages: 453-458
- DOI
  10.1111/neup.12817
- Data Source
  KAKENHI-PROJECT-22K09243
[Journal Article] Transsylvian and trans-Heschl’s gyrus approach for a left posterior insular lesion and functional analyses of the left Heschl’s gyrus: illustrative case2022
- Author(s)
  Nakae Shunsuke、Kumon Masanobu、Kojima Daijiro、Higashiguchi Saeko、Ohba Shigeo、Kuriyama Naohide、Sato Yuriko、Inamoto Yoko、Mukaino Masahiko、Hirose Yuichi
- Journal Title
  
  Journal of Neurosurgery: Case Lessons
  
  Volume: 3 Issue: 5
- DOI
  10.3171/case21622
- Data Source
  KAKENHI-PROJECT-22K09243
[Journal Article] A subset of PARP inhibitors induces lethal telomere fusion in ALT-dependent tumor cells2021
- Author(s)
  Mukherjee Joydeep、Pandita Ajay、Kamalakar Chatla、Johannessen Tor-Christian、Ohba Shigeo、Tang Yongjian、Dalle-Ore Cecilia L.、Bjerkvig Rolf、Pieper Russell O.
- Journal Title
  
  Science Translational Medicine
  
  Volume: 13 Issue: 592 Pages: 7211-7211
- DOI
  10.1126/scitranslmed.abc7211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09468
[Journal Article] Myoinositol to Total Choline Ratio in Glioblastomas as a Potential Prognostic Factor in Preoperative Magnetic Resonance Spectroscopy2021
- Author(s)
  KUMON Masanobu、NAKAE Shunsuke、MURAYAMA Kazuhiro、KATO Takema、OHBA Shigeo、INAMASU Joji、YAMADA Seiji、ABE Masato、SASAKI Hikaru、OHNO Yoshiharu、HASEGAWA Mitsuhiro、KURAHASHI Hiroki、HIROSE Yuichi
- Journal Title
  
  Neurol. Med. Chir.(Tokyo)
  
  Volume: 61 Issue: 8 Pages: 453-460
- DOI
  10.2176/nmc.oa.2020-0312
- NAID
  130008074598
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09464, KAKENHI-PROJECT-19K09468, KAKENHI-PROJECT-19K09490, KAKENHI-PROJECT-21K06283, KAKENHI-PROJECT-21K09161
[Journal Article] Association of preoperative seizures with tumor metabolites quantified by magnetic resonance spectroscopy in gliomas2021
- Author(s)
  Nakae Shunsuke、Kumon Masanobu、Murayama Kazuhiro、Ohba Shigeo、Sasaki Hikaru、Inamasu Joji、Kuwahara Kiyonori、Yamada Seiji、Abe Masato、Hirose Yuichi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 7927-7927
- DOI
  10.1038/s41598-021-86487-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09464, KAKENHI-PROJECT-19K09468, KAKENHI-PROJECT-19K09490, KAKENHI-PROJECT-20K09334, KAKENHI-PROJECT-21K09161
[Journal Article] Inhibition of DNA Repair in Combination with Temozolomide or Dianhydrogalactiol Overcomes Temozolomide-Resistant Glioma Cells2021
- Author(s)
  Ohba Shigeo、Yamashiro Kei、Hirose Yuichi
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 11 Pages: 2570-2570
- DOI
  10.3390/cancers13112570
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09468, KAKENHI-PROJECT-20K09334
[Journal Article] Correlation between IDH, ATRX, and TERT promoter mutations in glioma2020
- Author(s)
  Ohba Shigeo、Kuwahara Kiyonori、Yamada Seiji、Abe Masato、Hirose Yuichi
- Journal Title
  
  Brain Tumor Pathology
  
  Volume: 37 Issue: 2 Pages: 33-40
- DOI
  10.1007/s10014-020-00360-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09468, KAKENHI-PROJECT-20K09334
[Journal Article] Phosphoglycerate Mutase 1 Activates DNA Damage Repair via Regulation of WIP1 Activity2020
- Author(s)
  Ohba Shigeo、Johannessen Tor-Christian Aase、Chatla Kamalakar、Yang Xiaodong、Pieper Russell O.、Mukherjee Joydeep
- Journal Title
  
  Cell Reports
  
  Volume: 31 Issue: 2 Pages: 107518-107518
- DOI
  10.1016/j.celrep.2020.03.082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09468, KAKENHI-PROJECT-18H02998
[Journal Article] l-asparaginase and 6-diazo-5-oxo-l-norleucine synergistically inhibit the growth of glioblastoma cells2020
- Author(s)
  Ohba Shigeo、Hirose Yuichi
- Journal Title
  
  Journal of Neuro-Oncology
  
  Volume: 146 Issue: 3 Pages: 469-475
- DOI
  10.1007/s11060-019-03351-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09468
[Journal Article] Human Glioma Cells Acquire Temozolomide Resistance After Repeated Drug Exposure Via DNA Mismatch Repair Dysfunction.2020
- Author(s)
  Yamashiro K, Nakao K, Ohba S, Hirose Y.
- Journal Title
  
  Anticancer Research
  
  Volume: 40 Issue: 3 Pages: 1315-1323
- DOI
  10.21873/anticanres.14073
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10876, KAKENHI-PROJECT-20K09334
[Journal Article] c-Met Expression Is a Useful Marker for Prognosis Prediction in IDH-Mutant Lower-Grade Gliomas and IDH-Wildtype Glioblastomas2019
- Author(s)
  Ohba Shigeo、Yamada Yasuhiro、Murayama Kazuhiro、Sandika Eriel、Sasaki Hikaru、Yamada Seiji、Abe Masato、Hasegawa Mitsuhiro、Hirose Yuichi
- Journal Title
  
  World Neurosurgery
  
  Volume: 印刷中 Pages: e1042-e1049
- DOI
  10.1016/j.wneu.2019.03.040
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10773
[Journal Article] The Correlation of Fluorescence of Protoporphyrinogen IX and Status of Isocitrate Dehydrogenase in Gliomas2019
- Author(s)
  Ohba Shigeo、Murayama Kazuhiro、Kuwahara Kiyonori、Pareira Eriel Sandika、Nakae Shunsuke、Nishiyama Yuya、Adachi Kazuhide、Yamada Seiji、Sasaki Hikaru、Yamamoto Naoki、Abe Masato、Mukherjee Joydeep、Hasegawa Mitsuhiro、Pieper Russell O、Hirose Yuichi
- Journal Title
  
  Neurosurgery
  
  Volume: - Issue: 2 Pages: 408-417
- DOI
  10.1093/neuros/nyz524
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09468, KAKENHI-PROJECT-19K09490, KAKENHI-PROJECT-17K11495
[Journal Article] Mutant IDH1 Cooperates with ATRX Loss to Drive the Alternative Lengthening of Telomere Phenotype in Glioma2018
- Author(s)
  Mukherjee Joydeep、Johannessen Tor-Christian、Ohba Shigeo、Chow Tracy T.、Jones Lindsey、Pandita Ajay、Pieper Russell O.
- Journal Title
  
  Cancer Research
  
  Volume: 78 Issue: 11 Pages: 2966-2977
- DOI
  10.1158/0008-5472.can-17-2269
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10773
[Journal Article] A retrospective study of bevacizumab for treatment of brainstem glioma with malignant features2018
- Author(s)
  Moriya Shigeta、Ohba Shigeo、Adachi Kazuhide、Nishiyama Yuya、Hayashi Takuro、Nagahisa Shinya、Kaito Takafumi、Nakae Shunsuke、Hirose Yuichi
- Journal Title
  
  Journal of Clinical Neuroscience
  
  Volume: 47 Pages: 228-233
- DOI
  10.1016/j.jocn.2017.10.002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10773
[Journal Article] Association between mutant IDHs and tumorigenesis in gliomas.2018
- Author(s)
  Ohba S, Hirose Y
- Journal Title
  
  Med Mol Morphol.
  
  Volume: 51 Issue: 4 Pages: 194-198
- DOI
  10.1007/s00795-018-0189-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10876, KAKENHI-PROJECT-16K10773
[Presentation] TARGETING ASPARAGINE METABOLISM FOR TREATMENT OF PROGRESSING MALIGNANT GLIOMA.2023
- Author(s)
  Yuichi Hirose, Shigeo Ohba, Kei Yamashiro, Kazutaka Nakao, Takao Teranishi
- Organizer
  The 23rd International Conference on Brain Tumor Research and Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09334
[Presentation] ペントースリン酸経路抑制によるテモゾロミド感受性増強効果2023
- Author(s)
  大場茂生　寺西隆雄　廣瀬雄一
- Organizer
  第23回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-22K09243
[Presentation] Targeting amino acid metabolic vulnerabilities in IDH-mutant and IDH-wildtype gliomas2023
- Author(s)
  Shigeo Ohba, Takao Teranishi, Akiyoshi Hirayama, Keisuke Hitachi, Hisateru Yamaguchi, Manabu Natsumeda, Kensuke Tateishi, Russell O Pieper, Yuichi Hirose
- Organizer
  28th Annual Meeting and Education Day of the Society for Neuro-Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09243
[Presentation] IDH 変異型神経膠腫におけるグルタミン代謝を標的とした治療法の検討2022
- Author(s)
  大場茂生、平山明由、常陸圭介、山口央輝、棗田学、立石健祐、Joydeep Mukherjee、Russell O Pieper、廣瀬雄一
- Organizer
  第40回日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-22K09243
[Presentation] Targeting amino acid metabolic vulnerabilities in glioblastoma2022
- Author(s)
  Shigeo Ohba, Takao Teranishi, Yuichi Hirose
- Organizer
  27th Annual Meeting and Education Day of the Society for Neuro-Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K09243
[Presentation] 神経膠腫におけるアスパラギン合成酵素の役割2022
- Author(s)
  大場茂生、寺西隆雄、長谷川光広、廣瀬雄一
- Organizer
  第22回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-22K09243
[Presentation] グリオーマにおけるアミノ酸代謝を標的とした治療法の検討2022
- Author(s)
  大場茂生、平山明由、常陸圭介、山口央輝4、Joydeep Mukherjee、Russell O Pieper、廣瀬雄一
- Organizer
  日本脳神経外科学会第81回学術総会
- Data Source
  KAKENHI-PROJECT-22K09243
[Presentation] Targeting amino acid metabolic vulnerabilities in IDH-mutant and IDH-wildtype gliomas2021
- Author(s)
  Shigeo Ohba, Akiyoshi Hirayama, Keisuke Hitachi, Hisateru Yamaguchi, Joydeep Mukherjee, Russell O Pieper, Yuichi Hirose
- Organizer
  26th Annual Meeting and Education Day of the Society for Neuro-Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09468
[Presentation] IDH変異型、IDH野生型グリオーマにおけるアミノ酸代謝を標的とした治療法の検討2021
- Author(s)
  大場茂生、平山明由、常陸圭介、山口央輝、 Joydeep Mukherjee 、Russell O Pieper、廣瀬雄一
- Organizer
  日本脳神経外科学会第80回学術総会
- Data Source
  KAKENHI-PROJECT-19K09468
[Presentation] IDH変異型、IDH野生型神経膠腫におけるアミノ酸代謝を標的とした治療法の検討2021
- Author(s)
  大場茂生、平山明由、常陸圭介、山口央輝、 Joydeep Mukherjee 、Russell O Pieper、廣瀬雄一
- Organizer
  第39回日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09468
[Presentation] 変異型イソクエン酸デヒドロゲナーゼによるプロトポルフィリンⅨの変化2020
- Author(s)
  大場茂生
- Organizer
  第20回日本術中画像情報学会
- Data Source
  KAKENHI-PROJECT-19K09468
[Presentation] 変異型イソクエン酸デヒドロゲナーゼによるプロトポルフィリン蛍光の変化2020
- Author(s)
  大場茂生
- Organizer
  第38回日本脳腫瘍病理学会
- Data Source
  KAKENHI-PROJECT-19K09468
[Presentation] ホスホグリセリン酸ムターゼ１はWIP１活性を介してDNA損傷に対する修復を行う2020
- Author(s)
  大場茂生
- Organizer
  日本脳神経外科学会第79回学術総会
- Data Source
  KAKENHI-PROJECT-19K09468
[Presentation] Phosphoglycerate mutase 1 activates DNA damage repair via regulation of WIP1 activity2020
- Author(s)
  大場茂生
- Organizer
  第38回日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09468
[Presentation] 変異型イソクエン酸デヒドロゲナーゼがプロトポルフィリンⅨ蛍光に及ぼす影響2019
- Author(s)
  大場　茂生、村山　和宏、中江　俊介、安達　一英、西山　悠也、佐々木　光、山田　勢至、安倍　雅人、長谷川　光広、廣瀬　雄一
- Organizer
  第37回日本脳腫瘍学会
- Data Source
  KAKENHI-PROJECT-16K10773
[Presentation] テモゾロマイド耐性グリオーマに対する治療法2019
- Author(s)
  大場茂生、廣瀬雄一
- Organizer
  日本脳神経外科学会第78回学術総会
- Data Source
  KAKENHI-PROJECT-17K10876
[Presentation] Temozolomide誘発性G2/M arrestから見た悪性グリオーマにおけるTemozolomide耐性機構の検討2019
- Author(s)
  山城慧、大場茂生、中尾一貴、廣瀬雄一
- Organizer
  第20回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-17K10876
[Presentation] 変異型イソクエン酸デヒドロゲナーゼによるプロトポルフィリンⅨ蛍光の変化2019
- Author(s)
  大場茂生、村山和宏、桒原聖典、Pareira Eriel、中江俊介、西山悠也、安達一英、山田勢至、佐々木光、山本直樹、安倍雅人、Joydeep Mukherjee、長谷川光広、Russell Pieper、廣瀬雄一
- Organizer
  第20回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-19K09468
[Presentation] Attempts to overcome drug resistance of malignant glioma.2019
- Author(s)
  Hirose Y, Yamashiro K, Ohba S.
- Organizer
  The 3rd Symposium of WFNOS 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10876
[Presentation] Inhibition of homologous recombination, PARP inhibitor, or dianhydrodulcitol overcomes temozolomide-resistance in glioma cells.2019
- Author(s)
  Ohba S, Hirose Y.
- Organizer
  American Association for Cancer Research, 2019 Annual Meeting
- Data Source
  KAKENHI-PROJECT-17K10876
[Presentation] 変異型イソクエン酸デヒドロゲナーゼがプロトポルフィリンⅨ蛍光に及ぼす影響2019
- Author(s)
  大場茂生、村山和宏、中江俊介、安達一英、西山悠也、佐々木光、山田勢至、安倍雅人、長谷川光広、廣瀬雄一
- Organizer
  第37回日本脳腫瘍病理学会
- Data Source
  KAKENHI-PROJECT-19K09468
[Presentation] G2/M arrestから見た悪性グリオーマにおけるTemozolomide耐性機構の検討2019
- Author(s)
  山城慧、大場茂生、中尾一貴、廣瀬雄一
- Organizer
  第37回日本脳腫瘍学会
- Data Source
  KAKENHI-PROJECT-17K10876
[Presentation] ヒトグリオーマ細胞株を用いた悪性グリオーマにおけるtemozolomide耐性機構の検討2019
- Author(s)
  山城慧、大場茂生、中尾一貴、廣瀬雄一
- Organizer
  日本脳神経外科学会第78回学術総会
- Data Source
  KAKENHI-PROJECT-17K10876
[Presentation] PARP inhibitor, inhibition of homologous recombination, or dianhydrodulcitol can overcome temozolomide-resistance in glioma cells.2019
- Author(s)
  Ohba S, Hirose Y.
- Organizer
  Society for Neuro-oncology, 2019 Annual Meeting
- Data Source
  KAKENHI-PROJECT-17K10876
[Presentation] テモゾロマイド耐性グリオーマに対する治療法2019
- Author(s)
  大場茂生、廣瀬雄一
- Organizer
  第37回日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-17K10876
[Presentation] The correlation of fluorescence of protoporphyrinogen Ⅸ and molecular biological characters in gliomas2018
- Author(s)
  大場　茂生、村山　和宏、中江　俊介、安達　一英、西山　悠也、佐々木　光、山田　勢至、安倍　雅人、長谷川　光広、廣瀬　雄一
- Organizer
  the 36th annual meeting of the Japan society of brain tumor pathology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10773
[Presentation] The mechanisms of resistance to temozolomide in glioma cells2018
- Author(s)
  大場茂生　廣瀬雄一
- Organizer
  The 23rd Annual Meeting and Education Day of the Society for Neuro-Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10773
[Presentation] 培養細胞による研究から示唆された初発膠芽腫に対する化学療法増強法の重要性2018
- Author(s)
  廣瀬雄一, 大場茂生, 山城慧, 中江俊介,安達一英, 西山悠也, 長谷川光広
- Organizer
  一般社団法人日本脳神経外科学会　第77回学術総会
- Data Source
  KAKENHI-PROJECT-17K10876
[Presentation] グリオーマ細胞におけるテモゾロマイド耐性機構と再感受性獲得法2018
- Author(s)
  大場茂生　廣瀬雄一
- Organizer
  日本脳神経外科学会　第77回学術総会
- Data Source
  KAKENHI-PROJECT-16K10773
[Presentation] Inhibition of homologous recombination resensitizes temozolomide-resistant glioma cells to temozolomide2017
- Author(s)
  Shigeo Ohba, Yuichi Hirose
- Organizer
  5th Quadrennial Meeting of World Federation of Neuro-Oncology Societies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10876

1. Hirose Yuichi (60218849)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. 八幡直樹 (60450607)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 秦龍二 (90258153)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 佐々木光 (70245512)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. 常陸圭介 (10508469)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
6. 平山明由 (00572405)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
7. 中江俊介 (20622971)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 安達一英 (10338056)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 村山和宏 (40622931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. 大野良治 (30324924)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 植田高弘 (60897370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 池田裕隆 (70750959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 永田紘之 (70795608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 外山宏 (90247643)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 花松智武 (90837569)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 山口央輝 (70319250)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
17. 寺西隆雄 (80899063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
18. 広瀬雄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 40 results

Ohba Shigeo 大場 茂生

OHBA SHIGEO 大場 茂生

Research Projects

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Co-Researchers

グリオーマに対するテモゾロミドとALDH阻害剤併用療法の開発Principal Investigator

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Mechanisim of drug resistance and genomic instability associated with tumor progression of malignant glioma

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3次元化学交換飽和移動画像のAIによる新規再構成法と神経膠腫診断支援システム開発

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神経膠腫におけるがん代謝を標的とした治療法の開発Principal Investigator

Principal Investigator

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Association of drug resistance of human malignant glioma cells and DNA repair system

Principal Investigator

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Elucidation of the mechanism of tumorigenesis and development of new treatments using iPS cell-derived mutant IDH glioma modelPrincipal Investigator

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Mechanisim of acqired drug resistance by glioma

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Mutant IDH-induced iPS-derived glioma cellsPrincipal Investigator

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[Journal Article] Three-Dimensional Gradient-Echo Based Amide Proton Transfer-Weighted Imaging of Brain Tumors: Comparison With Two-Dimensional Spin-Echo?Based Amide Proton Transfer-Weighted Imaging2023

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[Journal Article] Applied Fence-Post Techniques Using Deep Electrodes Instead of Catheters for Resection of Glioma Complicated with Frequent Epileptic Seizures: A Case Report2023

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[Journal Article] Three-Dimensional Amide Proton Transfer-Weighted Imaging for Differentiating between Glioblastoma, IDH-Wildtype and Primary Central Nervous System Lymphoma2023

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[Journal Article] Carotid Plaque Diagnosis With 3-Dimensional Computed Tomography Angiography: A Comparison With Magnetic Resonance Imaging?Based Plaque Diagnosis2023

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[Journal Article] Intracranial phosphaturic mesenchymal tumors. A case report and review of literature2022

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[Journal Article] Transsylvian and trans-Heschl’s gyrus approach for a left posterior insular lesion and functional analyses of the left Heschl’s gyrus: illustrative case2022

Author(s)

Ohba Shigeo 大場茂生

OHBA SHIGEO 大場茂生