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Ohba Shigeo  大場 茂生

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OHBA SHIGEO  大場 茂生

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Researcher Number 80338061
Affiliation (Current) 2025: 藤田医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help 2025: 藤田医科大学, 医学部, 准教授
2018 – 2023: 藤田医科大学, 医学部, 准教授
2016 – 2017: 藤田保健衛生大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
Basic Section 56010:Neurosurgery-related / Neurosurgery
Except Principal Investigator
Basic Section 56010:Neurosurgery-related / Basic Section 52040:Radiological sciences-related / Neurosurgery
Keywords
Principal Investigator
がん代謝 / 神経膠腫 / IDH変異 / IDH / 網羅的代謝解析 / 網羅的遺伝子解析 / グリオーマ / iPS / グルタミン / アスパラギン … More / IDH1 / 代謝 / 腫瘍化 / 変異型IDH / mutant IDH / glioma … More
Except Principal Investigator
DNAミスマッチ修復 / 薬剤耐性 / DNAメチル化剤 / 膠芽腫 / 悪性神経膠腫 / G2チェックポイント / テモゾロミド / 神経膠腫 / ミスマッチ修復 / DNA相同組換え修復 / 人工知能 / 3次元化学交換飽和移動画像 / 脳腫瘍 / 髄膜腫 / 化学交換飽和移動イメージング / 磁気共鳴画像 / temozolomide / DNA修復機構 / シグナル伝達 / トランスレーショナルリサーチ / 薬剤反応性 / 癌 / 脳神経疾患 / 耐性 Less
  • Research Projects

    (8 results)
  • Research Products

    (49 results)
  • Co-Researchers

    (18 People)
  •  グリオーマに対するテモゾロミドとALDH阻害剤併用療法の開発Principal Investigator

    • Principal Investigator
      大場 茂生
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Fujita Health University
  •  Mechanisim of drug resistance and genomic instability associated with tumor progression of malignant glioma

    • Principal Investigator
      廣瀬 雄一
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Fujita Health University
  •  3次元化学交換飽和移動画像のAIによる新規再構成法と神経膠腫診断支援システム開発

    • Principal Investigator
      村山 和宏
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Fujita Health University
  •  神経膠腫におけるがん代謝を標的とした治療法の開発Principal Investigator

    • Principal Investigator
      大場 茂生
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Fujita Health University
  •  Association of drug resistance of human malignant glioma cells and DNA repair system

    • Principal Investigator
      Hirose Yuichi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Fujita Health University
  •  Elucidation of the mechanism of tumorigenesis and development of new treatments using iPS cell-derived mutant IDH glioma modelPrincipal Investigator

    • Principal Investigator
      OHBA SHIGEO
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Fujita Health University
  •  Mechanisim of acqired drug resistance by glioma

    • Principal Investigator
      Hirose Yuichi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      Fujita Health University
  •  Mutant IDH-induced iPS-derived glioma cellsPrincipal Investigator

    • Principal Investigator
      OHBA SHIGEO
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      Fujita Health University

All 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

  • [Journal Article] Three-Dimensional Gradient-Echo Based Amide Proton Transfer-Weighted Imaging of Brain Tumors: Comparison With Two-Dimensional Spin-Echo?Based Amide Proton Transfer-Weighted Imaging2023

    • Author(s)
      Murayama Kazuhiro、Ohno Yoshiharu、Yui Masao、Yamamoto Kaori、Ikedo Masato、Ohba Shigeo、Hanamatsu Satomu、Iwase Akiyoshi、Ikeda Hirotaka、Hirose Yuichi、Toyama Hiroshi
    • Journal Title

      Journal of Computer Assisted Tomography

      Volume: Publish Ahead of Print Issue: 3 Pages: 494-499

    • DOI

      10.1097/rct.0000000000001432

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K07679, KAKENHI-PROJECT-22K09243
  • [Journal Article] Applied Fence-Post Techniques Using Deep Electrodes Instead of Catheters for Resection of Glioma Complicated with Frequent Epileptic Seizures: A Case Report2023

    • Author(s)
      Nakae Shunsuke、Kumon Masanobu、Teranishi Takao、Ohba Shigeo、Hirose Yuichi
    • Journal Title

      Brain Sciences

      Volume: 13 Issue: 3 Pages: 482-482

    • DOI

      10.3390/brainsci13030482

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09243, KAKENHI-PROJECT-21K16621
  • [Journal Article] Three-Dimensional Amide Proton Transfer-Weighted Imaging for Differentiating between Glioblastoma, IDH-Wildtype and Primary Central Nervous System Lymphoma2023

    • Author(s)
      Ohba Shigeo、Murayama Kazuhiro、Teranishi Takao、Kumon Masanobu、Nakae Shunsuke、Yui Masao、Yamamoto Kaori、Yamada Seiji、Abe Masato、Hasegawa Mitsuhiro、Hirose Yuichi
    • Journal Title

      Cancers

      Volume: 15 Issue: 3 Pages: 952-952

    • DOI

      10.3390/cancers15030952

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K07679, KAKENHI-PROJECT-22K09243
  • [Journal Article] Carotid Plaque Diagnosis With 3-Dimensional Computed Tomography Angiography: A Comparison With Magnetic Resonance Imaging?Based Plaque Diagnosis2023

    • Author(s)
      Omi Tatsuo、Hayakawa Motoharu、Adachi Kazuhide、Ohba Shigeo、Sadato Akiyo、Hasebe Akiko、Ishihara Takuma、Nakahara Ichiro、Hirose Yuichi
    • Journal Title

      Journal of Computer Assisted Tomography

      Volume: 47 Pages: 488-493

    • DOI

      10.1097/rct.0000000000001416

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09243, KAKENHI-PROJECT-22H00190
  • [Journal Article] Intracranial phosphaturic mesenchymal tumors. A case report and review of literature2022

    • Author(s)
      Kojima Daijiro、Ohba Shigeo、Abe Masato、Suzuki Atsushi、Horibe Seiji、Tateya Ichiro、Hasegawa Mitsuhiro、Hirose Yuichi
    • Journal Title

      Neuropathology

      Volume: 42 Issue: 5 Pages: 453-458

    • DOI

      10.1111/neup.12817

    • Data Source
      KAKENHI-PROJECT-22K09243
  • [Journal Article] Transsylvian and trans-Heschl’s gyrus approach for a left posterior insular lesion and functional analyses of the left Heschl’s gyrus: illustrative case2022

    • Author(s)
      Nakae Shunsuke、Kumon Masanobu、Kojima Daijiro、Higashiguchi Saeko、Ohba Shigeo、Kuriyama Naohide、Sato Yuriko、Inamoto Yoko、Mukaino Masahiko、Hirose Yuichi
    • Journal Title

      Journal of Neurosurgery: Case Lessons

      Volume: 3 Issue: 5

    • DOI

      10.3171/case21622

    • Data Source
      KAKENHI-PROJECT-22K09243
  • [Journal Article] A subset of PARP inhibitors induces lethal telomere fusion in ALT-dependent tumor cells2021

    • Author(s)
      Mukherjee Joydeep、Pandita Ajay、Kamalakar Chatla、Johannessen Tor-Christian、Ohba Shigeo、Tang Yongjian、Dalle-Ore Cecilia L.、Bjerkvig Rolf、Pieper Russell O.
    • Journal Title

      Science Translational Medicine

      Volume: 13 Issue: 592 Pages: 7211-7211

    • DOI

      10.1126/scitranslmed.abc7211

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09468
  • [Journal Article] Myoinositol to Total Choline Ratio in Glioblastomas as a Potential Prognostic Factor in Preoperative Magnetic Resonance Spectroscopy2021

    • Author(s)
      KUMON Masanobu、NAKAE Shunsuke、MURAYAMA Kazuhiro、KATO Takema、OHBA Shigeo、INAMASU Joji、YAMADA Seiji、ABE Masato、SASAKI Hikaru、OHNO Yoshiharu、HASEGAWA Mitsuhiro、KURAHASHI Hiroki、HIROSE Yuichi
    • Journal Title

      Neurol. Med. Chir.(Tokyo)

      Volume: 61 Issue: 8 Pages: 453-460

    • DOI

      10.2176/nmc.oa.2020-0312

    • NAID

      130008074598

    • ISSN
      0470-8105, 1349-8029
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09464, KAKENHI-PROJECT-19K09468, KAKENHI-PROJECT-19K09490, KAKENHI-PROJECT-21K06283, KAKENHI-PROJECT-21K09161
  • [Journal Article] Association of preoperative seizures with tumor metabolites quantified by magnetic resonance spectroscopy in gliomas2021

    • Author(s)
      Nakae Shunsuke、Kumon Masanobu、Murayama Kazuhiro、Ohba Shigeo、Sasaki Hikaru、Inamasu Joji、Kuwahara Kiyonori、Yamada Seiji、Abe Masato、Hirose Yuichi
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 7927-7927

    • DOI

      10.1038/s41598-021-86487-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09464, KAKENHI-PROJECT-19K09468, KAKENHI-PROJECT-19K09490, KAKENHI-PROJECT-20K09334, KAKENHI-PROJECT-21K09161
  • [Journal Article] Inhibition of DNA Repair in Combination with Temozolomide or Dianhydrogalactiol Overcomes Temozolomide-Resistant Glioma Cells2021

    • Author(s)
      Ohba Shigeo、Yamashiro Kei、Hirose Yuichi
    • Journal Title

      Cancers

      Volume: 13 Issue: 11 Pages: 2570-2570

    • DOI

      10.3390/cancers13112570

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09468, KAKENHI-PROJECT-20K09334
  • [Journal Article] Correlation between IDH, ATRX, and TERT promoter mutations in glioma2020

    • Author(s)
      Ohba Shigeo、Kuwahara Kiyonori、Yamada Seiji、Abe Masato、Hirose Yuichi
    • Journal Title

      Brain Tumor Pathology

      Volume: 37 Issue: 2 Pages: 33-40

    • DOI

      10.1007/s10014-020-00360-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09468, KAKENHI-PROJECT-20K09334
  • [Journal Article] Phosphoglycerate Mutase 1 Activates DNA Damage Repair via Regulation of WIP1 Activity2020

    • Author(s)
      Ohba Shigeo、Johannessen Tor-Christian Aase、Chatla Kamalakar、Yang Xiaodong、Pieper Russell O.、Mukherjee Joydeep
    • Journal Title

      Cell Reports

      Volume: 31 Issue: 2 Pages: 107518-107518

    • DOI

      10.1016/j.celrep.2020.03.082

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09468, KAKENHI-PROJECT-18H02998
  • [Journal Article] l-asparaginase and 6-diazo-5-oxo-l-norleucine synergistically inhibit the growth of glioblastoma cells2020

    • Author(s)
      Ohba Shigeo、Hirose Yuichi
    • Journal Title

      Journal of Neuro-Oncology

      Volume: 146 Issue: 3 Pages: 469-475

    • DOI

      10.1007/s11060-019-03351-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09468
  • [Journal Article] Human Glioma Cells Acquire Temozolomide Resistance After Repeated Drug Exposure Via DNA Mismatch Repair Dysfunction.2020

    • Author(s)
      Yamashiro K, Nakao K, Ohba S, Hirose Y.
    • Journal Title

      Anticancer Research

      Volume: 40 Issue: 3 Pages: 1315-1323

    • DOI

      10.21873/anticanres.14073

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10876, KAKENHI-PROJECT-20K09334
  • [Journal Article] c-Met Expression Is a Useful Marker for Prognosis Prediction in IDH-Mutant Lower-Grade Gliomas and IDH-Wildtype Glioblastomas2019

    • Author(s)
      Ohba Shigeo、Yamada Yasuhiro、Murayama Kazuhiro、Sandika Eriel、Sasaki Hikaru、Yamada Seiji、Abe Masato、Hasegawa Mitsuhiro、Hirose Yuichi
    • Journal Title

      World Neurosurgery

      Volume: 印刷中 Pages: e1042-e1049

    • DOI

      10.1016/j.wneu.2019.03.040

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10773
  • [Journal Article] The Correlation of Fluorescence of Protoporphyrinogen IX and Status of Isocitrate Dehydrogenase in Gliomas2019

    • Author(s)
      Ohba Shigeo、Murayama Kazuhiro、Kuwahara Kiyonori、Pareira Eriel Sandika、Nakae Shunsuke、Nishiyama Yuya、Adachi Kazuhide、Yamada Seiji、Sasaki Hikaru、Yamamoto Naoki、Abe Masato、Mukherjee Joydeep、Hasegawa Mitsuhiro、Pieper Russell O、Hirose Yuichi
    • Journal Title

      Neurosurgery

      Volume: - Issue: 2 Pages: 408-417

    • DOI

      10.1093/neuros/nyz524

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09468, KAKENHI-PROJECT-19K09490, KAKENHI-PROJECT-17K11495
  • [Journal Article] Mutant IDH1 Cooperates with ATRX Loss to Drive the Alternative Lengthening of Telomere Phenotype in Glioma2018

    • Author(s)
      Mukherjee Joydeep、Johannessen Tor-Christian、Ohba Shigeo、Chow Tracy T.、Jones Lindsey、Pandita Ajay、Pieper Russell O.
    • Journal Title

      Cancer Research

      Volume: 78 Issue: 11 Pages: 2966-2977

    • DOI

      10.1158/0008-5472.can-17-2269

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10773
  • [Journal Article] A retrospective study of bevacizumab for treatment of brainstem glioma with malignant features2018

    • Author(s)
      Moriya Shigeta、Ohba Shigeo、Adachi Kazuhide、Nishiyama Yuya、Hayashi Takuro、Nagahisa Shinya、Kaito Takafumi、Nakae Shunsuke、Hirose Yuichi
    • Journal Title

      Journal of Clinical Neuroscience

      Volume: 47 Pages: 228-233

    • DOI

      10.1016/j.jocn.2017.10.002

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10773
  • [Journal Article] Association between mutant IDHs and tumorigenesis in gliomas.2018

    • Author(s)
      Ohba S, Hirose Y
    • Journal Title

      Med Mol Morphol.

      Volume: 51 Issue: 4 Pages: 194-198

    • DOI

      10.1007/s00795-018-0189-8

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10876, KAKENHI-PROJECT-16K10773
  • [Presentation] TARGETING ASPARAGINE METABOLISM FOR TREATMENT OF PROGRESSING MALIGNANT GLIOMA.2023

    • Author(s)
      Yuichi Hirose, Shigeo Ohba, Kei Yamashiro, Kazutaka Nakao, Takao Teranishi
    • Organizer
      The 23rd International Conference on Brain Tumor Research and Therapy
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K09334
  • [Presentation] ペントースリン酸経路抑制による テモゾロミド感受性増強効果2023

    • Author(s)
      大場茂生 寺西隆雄 廣瀬雄一
    • Organizer
      第23回日本分子脳神経外科学会
    • Data Source
      KAKENHI-PROJECT-22K09243
  • [Presentation] Targeting amino acid metabolic vulnerabilities in IDH-mutant and IDH-wildtype gliomas2023

    • Author(s)
      Shigeo Ohba, Takao Teranishi, Akiyoshi Hirayama, Keisuke Hitachi, Hisateru Yamaguchi, Manabu Natsumeda, Kensuke Tateishi, Russell O Pieper, Yuichi Hirose
    • Organizer
      28th Annual Meeting and Education Day of the Society for Neuro-Oncology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K09243
  • [Presentation] IDH 変異型神経膠腫におけるグルタミン代謝を標的とした治療法の検討2022

    • Author(s)
      大場茂生、平山明由、常陸圭介、山口央輝、棗田学、立石健祐、Joydeep Mukherjee、Russell O Pieper、廣瀬雄一
    • Organizer
      第40回日本脳腫瘍学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K09243
  • [Presentation] Targeting amino acid metabolic vulnerabilities in glioblastoma2022

    • Author(s)
      Shigeo Ohba, Takao Teranishi, Yuichi Hirose
    • Organizer
      27th Annual Meeting and Education Day of the Society for Neuro-Oncology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K09243
  • [Presentation] 神経膠腫におけるアスパラギン合成酵素の役割2022

    • Author(s)
      大場茂生、寺西隆雄、長谷川光広、廣瀬雄一
    • Organizer
      第22回日本分子脳神経外科学会
    • Data Source
      KAKENHI-PROJECT-22K09243
  • [Presentation] グリオーマにおけるアミノ酸代謝を標的とした治療法の検討2022

    • Author(s)
      大場茂生、平山明由、常陸圭介、山口央輝4、Joydeep Mukherjee、Russell O Pieper、廣瀬雄一
    • Organizer
      日本脳神経外科学会 第81回学術総会
    • Data Source
      KAKENHI-PROJECT-22K09243
  • [Presentation] Targeting amino acid metabolic vulnerabilities in IDH-mutant and IDH-wildtype gliomas2021

    • Author(s)
      Shigeo Ohba, Akiyoshi Hirayama, Keisuke Hitachi, Hisateru Yamaguchi, Joydeep Mukherjee, Russell O Pieper, Yuichi Hirose
    • Organizer
      26th Annual Meeting and Education Day of the Society for Neuro-Oncology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09468
  • [Presentation] IDH変異型、IDH野生型グリオーマにおけるアミノ酸代謝を標的とした治療法の検討2021

    • Author(s)
      大場茂生、 平山明由、常陸圭介、山口央輝、 Joydeep Mukherjee 、Russell O Pieper、廣瀬雄一
    • Organizer
      日本脳神経外科学会 第80回学術総会
    • Data Source
      KAKENHI-PROJECT-19K09468
  • [Presentation] IDH変異型、IDH野生型神経膠腫におけるアミノ酸代謝を標的とした治療法の検討2021

    • Author(s)
      大場茂生、 平山明由、常陸圭介、山口央輝、 Joydeep Mukherjee 、Russell O Pieper、廣瀬雄一
    • Organizer
      第39回日本脳腫瘍学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K09468
  • [Presentation] 変異型イソクエン酸デヒドロゲナーゼによるプロトポルフィリンⅨの変化2020

    • Author(s)
      大場茂生
    • Organizer
      第20回日本術中画像情報学会
    • Data Source
      KAKENHI-PROJECT-19K09468
  • [Presentation] 変異型イソクエン酸デヒドロゲナーゼによるプロトポルフィリン蛍光の変化2020

    • Author(s)
      大場茂生
    • Organizer
      第38回日本脳腫瘍病理学会
    • Data Source
      KAKENHI-PROJECT-19K09468
  • [Presentation] ホスホグリセリン酸ムターゼ1はWIP1活性を介してDNA損傷に対する修復を行う2020

    • Author(s)
      大場茂生
    • Organizer
      日本脳神経外科学会第79回学術総会
    • Data Source
      KAKENHI-PROJECT-19K09468
  • [Presentation] Phosphoglycerate mutase 1 activates DNA damage repair via regulation of WIP1 activity2020

    • Author(s)
      大場茂生
    • Organizer
      第38回日本脳腫瘍学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K09468
  • [Presentation] 変異型イソクエン酸デヒドロゲナーゼがプロトポルフィリンⅨ蛍光に及ぼす影響2019

    • Author(s)
      大場 茂生、村山 和宏、中江 俊介、安達 一英、西山 悠也、佐々木 光、 山田 勢至、安倍 雅人、長谷川 光広、廣瀬 雄一
    • Organizer
      第37回日本脳腫瘍学会
    • Data Source
      KAKENHI-PROJECT-16K10773
  • [Presentation] テモゾロマイド耐性グリオーマに対する治療法2019

    • Author(s)
      大場茂生、廣瀬雄一
    • Organizer
      日本脳神経外科学会 第78回学術総会
    • Data Source
      KAKENHI-PROJECT-17K10876
  • [Presentation] Temozolomide誘発性G2/M arrestから見た悪性グリオーマにおけるTemozolomide耐性機構の検討2019

    • Author(s)
      山城慧、大場茂生、 中尾一貴、 廣瀬雄一
    • Organizer
      第20回日本分子脳神経外科学会
    • Data Source
      KAKENHI-PROJECT-17K10876
  • [Presentation] 変異型イソクエン酸デヒドロゲナーゼによるプロトポルフィリンⅨ蛍光の変化2019

    • Author(s)
      大場茂生、村山和宏、桒原聖典、Pareira Eriel、中江俊介、西山悠也、安達一英、山田勢至、佐々木光、山本直樹、安倍雅人、Joydeep Mukherjee、長谷川光広、Russell Pieper、廣瀬雄一
    • Organizer
      第20回日本分子脳神経外科学会
    • Data Source
      KAKENHI-PROJECT-19K09468
  • [Presentation] Attempts to overcome drug resistance of malignant glioma.2019

    • Author(s)
      Hirose Y, Yamashiro K, Ohba S.
    • Organizer
      The 3rd Symposium of WFNOS 2021
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10876
  • [Presentation] Inhibition of homologous recombination, PARP inhibitor, or dianhydrodulcitol overcomes temozolomide-resistance in glioma cells.2019

    • Author(s)
      Ohba S, Hirose Y.
    • Organizer
      American Association for Cancer Research, 2019 Annual Meeting
    • Data Source
      KAKENHI-PROJECT-17K10876
  • [Presentation] 変異型イソクエン酸デヒドロゲナーゼがプロトポルフィリンⅨ蛍光に及ぼす影響2019

    • Author(s)
      大場茂生、村山和宏、中江俊介、安達一英、西山悠也、 佐々木光、山田勢至、安倍雅人、長谷川光広、廣瀬雄一
    • Organizer
      第37回日本脳腫瘍病理学会
    • Data Source
      KAKENHI-PROJECT-19K09468
  • [Presentation] G2/M arrestから見た悪性グリオーマにおけるTemozolomide耐性機構の検討2019

    • Author(s)
      山城慧、大場茂生、 中尾一貴、 廣瀬雄一
    • Organizer
      第37回日本脳腫瘍学会
    • Data Source
      KAKENHI-PROJECT-17K10876
  • [Presentation] ヒトグリオーマ細胞株を用いた悪性グリオーマにおけるtemozolomide耐性機構の検討2019

    • Author(s)
      山城慧、大場茂生、 中尾一貴、 廣瀬雄一
    • Organizer
      日本脳神経外科学会第78回学術総会
    • Data Source
      KAKENHI-PROJECT-17K10876
  • [Presentation] PARP inhibitor, inhibition of homologous recombination, or dianhydrodulcitol can overcome temozolomide-resistance in glioma cells.2019

    • Author(s)
      Ohba S, Hirose Y.
    • Organizer
      Society for Neuro-oncology, 2019 Annual Meeting
    • Data Source
      KAKENHI-PROJECT-17K10876
  • [Presentation] テモゾロマイド耐性グリオーマに対する治療法2019

    • Author(s)
      大場茂生、廣瀬雄一
    • Organizer
      第37回日本脳腫瘍学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K10876
  • [Presentation] The correlation of fluorescence of protoporphyrinogen Ⅸ and molecular biological characters in gliomas2018

    • Author(s)
      大場 茂生、村山 和宏、中江 俊介、安達 一英、西山 悠也、佐々木 光、 山田 勢至、安倍 雅人、長谷川 光広、廣瀬 雄一
    • Organizer
      the 36th annual meeting of the Japan society of brain tumor pathology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10773
  • [Presentation] The mechanisms of resistance to temozolomide in glioma cells2018

    • Author(s)
      大場茂生 廣瀬雄一
    • Organizer
      The 23rd Annual Meeting and Education Day of the Society for Neuro-Oncology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10773
  • [Presentation] 培養細胞による研究から示唆された初発膠芽腫に対する化学療法増強法の重要性2018

    • Author(s)
      廣瀬雄一, 大場茂生, 山城 慧, 中江俊介,安達一英, 西山悠也, 長谷川光広
    • Organizer
      一般社団法人 日本脳神経外科学会 第77回学術総会
    • Data Source
      KAKENHI-PROJECT-17K10876
  • [Presentation] グリオーマ細胞におけるテモゾロマイド耐性機構と再感受性獲得法2018

    • Author(s)
      大場茂生 廣瀬雄一
    • Organizer
      日本脳神経外科学会 第77回学術総会
    • Data Source
      KAKENHI-PROJECT-16K10773
  • [Presentation] Inhibition of homologous recombination resensitizes temozolomide-resistant glioma cells to temozolomide2017

    • Author(s)
      Shigeo Ohba, Yuichi Hirose
    • Organizer
      5th Quadrennial Meeting of World Federation of Neuro-Oncology Societies
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10876
  • 1.  Hirose Yuichi (60218849)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 2.  八幡 直樹 (60450607)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  秦 龍二 (90258153)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  佐々木 光 (70245512)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 5.  常陸 圭介 (10508469)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 6.  平山 明由 (00572405)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 7.  中江 俊介 (20622971)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  安達 一英 (10338056)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  村山 和宏 (40622931)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 10.  大野 良治 (30324924)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  植田 高弘 (60897370)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  池田 裕隆 (70750959)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  永田 紘之 (70795608)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  外山 宏 (90247643)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 15.  花松 智武 (90837569)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 16.  山口 央輝 (70319250)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 17.  寺西 隆雄 (80899063)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 18.  広瀬 雄一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 40 results

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