Tsubamoto Hiroshi 鍔本浩志

… Alternative Names

TSUBAMOTO Hiroshi 鍔本浩志

TSUBAMOTO HIROSI 鍔本浩志

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Researcher Number	80340975
Other IDs
Affiliation (Current)	2025: 兵庫医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2025: 兵庫医科大学, 医学部, 教授 2021 – 2023: 兵庫医科大学, 医学部, 教授 2019: 兵庫医科大学, 医学部, 教授 2016 – 2018: 兵庫医科大学, 医学部, 准教授 2002 – 2005: 兵庫医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology / Obstetrics and gynecology Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology / Embryonic/Neonatal medicine / Medical pharmacy
Keywords	Principal Investigator イトラコナゾール / ドラッグ・リポジショニング / 脂質メディエーター / レゾルビン / 再分極 / 腫瘍関連マクロファージ / 腫瘍微小環境 / 悪性腫瘍 / 医療 / ABCA1 … More / AKT/mTOR / 子宮体癌 / リポジショニング / anticancer / repurposing / repositioning / トランスレーショナルリサーチ / 創薬 / リポジショニングドラッグ / がん治療 / 精子蛋白 / 自己免疫 / 自己免疫疾患 / 不妊症 / 抗精子抗体 … More Except Principal Investigator hypochondroplasia / PCR / thanatophoric dysplasia / FGFR3 / MDSC / C-reactive protein / LOX-1 / 免疫チェックポイント阻害剤 / バイオマーカー / 抗がん治療薬 / repurposing / repositioning / リポジショニング / リポジショニングドラッグ / ドラッグリポジショニング / osteochondrodysplasias / 致死性骨異形成症 / 骨系統疾患 / infertility / fertilization blockin / nasal immunity / immuno-contraceptive vaccine / GPI anchor protein / carbohydrate epitope of CD52 / sperm antigen / 粘膜免疫 / 精巣上体 / CD52 / 受精 / 卵透明帯 / 不妊症 / 受精阻害 / 鼻腔免疫 / 避妊ワクチン / GPIアンカータンパク / CD52特異糖鎖 / 精子抗原 Less

CRP-LOX1 axisがMDSCの免疫抑制能とPD-1/PD-L1阻害薬の効果に及ぼす影響
- Principal Investigator
  
  上田友子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Hyogo Medical University
Exploration of novel anticancer activity via bioactive lipid mediators including resolvins E2/E3Principal Investigator
- Principal Investigator
  
  Tsubamoto Hiroshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Hyogo Medical University
Identification of anticancer mechanism of itraconazole and its clinical responders
- Principal Investigator
  
  Inoue Kayo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Hyogo Medical University
Identification of anti-cancer mechanism and responder by itraconazole in endometrial cancerPrincipal Investigator
- Principal Investigator
  
  TSUBAMOTO Hiroshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Hyogo Medical University
Nasal immunization with mature sperm specific antigen CD52 for developing a contraceptive vaccine
- Principal Investigator
  
  AKATANI AKIKO
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Hyogo College of Medicine
Genetic analysis of fibroblast growth factor receptor 3 (FGFR3) gene that cause congenital osteochondrodysplasias.
- Principal Investigator
  
  SAWAI Hideaki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  Hyogo College of Medicine
IgA抗精子抗体産生に関わる粘膜免疫機構の解明Principal Investigator
- Principal Investigator
  
  鍔本浩志
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Hyogo Medical University

All 2023 2021 2018 2017 2016

All Journal Article

[Journal Article] Itraconazole Modulates Phospholipid Levels in Tumor-associated Macrophages2023
- Author(s)
  Takimoto Y, Tsubamoto H, Isono-Taniguchi R, Ueda T, Sakata K, Nakagawa K, Narita S, Wakimoto YU, Shibahara H, Nishiumi S.
- Journal Title
  
  Anticancer Res.
  
  Volume: 43 Issue: 5 Pages: 1981-1984
- DOI
  10.21873/anticanres.16358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K12676, KAKENHI-PROJECT-21K09459
[Journal Article] . Itraconazole Repolarizes Tumor-associated Macrophages and Suppresses Cervical Cancer Cell Growth.2023
- Author(s)
  Takimoto Y, Tsubamoto H, Taniguchi R, Sakata K, Takada Y, Adachi J, Tomonaga T, Ueda T, Nakagawa K, Narita S, Wakimoto YU, Shibahara H.
- Journal Title
  
  Anticancer Res.
  
  Volume: 43 Issue: 2 Pages: 569-580
- DOI
  10.21873/anticanres.16193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09459
[Journal Article] Itraconazole Increases Resolvin E3 Concentration and 12/15-lipoxygenase Inhibitor Attenuates Itraconazole Cytotoxicity in Cervical Cancer Cells2021
- Author(s)
  Isono R, Tsubamoto H, Inoue K, Ueda T, Takimoto Y, Sakata K, Shinohara M, Shibahara H.
- Journal Title
  
  Anticancer Res
  
  Volume: 41 Issue: 9 Pages: 4271-4276
- DOI
  10.21873/anticanres.15231
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09459
[Journal Article] Itraconazole treatment of primary malignant melanoma of the vagina evaluated using positron emission tomography and tissue cDNA microarray: a case report2018
- Author(s)
  Inoue Kayo、Tsubamoto Hiroshi、Isono-Nakata Roze、Sakata Kazuko、Nakagomi Nami
- Journal Title
  
  BMC Cancer
  
  Volume: 18 Issue: 1 Pages: 630-635
- DOI
  10.1186/s12885-018-4520-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11306, KAKENHI-PROJECT-16K11166
[Journal Article] Itraconazole Inhibits AKT/mTOR Signaling and Proliferation in Endometrial Cancer Cells.2017
- Author(s)
  Tsubamoto H, et al.
- Journal Title
  
  Anticancer Res.
  
  Volume: 37 Issue: 2 Pages: 515-519
- DOI
  10.21873/anticanres.11343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11166
[Journal Article] Repurposing itraconazole as an anticancer agent: A review2017
- Author(s)
  Tsubamoto H, et al.
- Journal Title
  
  Oncol Lett.
  
  Volume: 14 Issue: 2 Pages: 1240-1246
- DOI
  10.3892/ol.2017.6325
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11166, KAKENHI-PROJECT-17K11306
[Journal Article] Itraconazole Modulates Hedgehog, WNT/β-catenin, as well as Akt Signalling, and Inhibits Proliferation of Cervical Cancer Cells.2017
- Author(s)
  Ueda T, Tsubamoto H, Inoue K, Sakata K, Shibahara H, Sonoda T.
- Journal Title
  
  Anticancer Res
  
  Volume: 37 Issue: 7 Pages: 3521-3526
- DOI
  10.21873/anticanres.11720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11306
[Journal Article] Repurposing itraconazole as an anticancer agent: A review.2017
- Author(s)
  Tsubamoto H, Ueda T, Inoue K, Sakata K, Shibahara H, Sonoda T.
- Journal Title
  
  Oncology Letters
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11166
[Journal Article] Expression of Hedgehog Signals and Growth Inhibition by Itraconazole in Endometrial Cancer.2016
- Author(s)
  Inoue K, Tsubamoto H, Sakata K, Sakane R, Hao H, Hirota S, Sonoda T, Shibahara H.
- Journal Title
  
  Anticancer Res.
  
  Volume: 36 Pages: 149-153
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11166

1. Inoue Kayo (80594754)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
2. SAWAI HIDEAKI (80215904)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 上田友子 (50793585)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. AKATANI AKIKO (50212402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KOMORI Shinji (60195865)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KOYAMA Koji (00068496)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KONDO Nobuyuki (70252682)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 馬淵誠士 (00452441)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 谷口路善 (80963868)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NISHIUMI Shin

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tsubamoto Hiroshi 鍔本 浩志

TSUBAMOTO Hiroshi 鍔本 浩志

TSUBAMOTO HIROSI 鍔本 浩志

Research Projects

Research Products

Co-Researchers

CRP-LOX1 axisがMDSCの免疫抑制能とPD-1/PD-L1阻害薬の効果に及ぼす影響

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploration of novel anticancer activity via bioactive lipid mediators including resolvins E2/E3Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of anticancer mechanism of itraconazole and its clinical responders

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of anti-cancer mechanism and responder by itraconazole in endometrial cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Nasal immunization with mature sperm specific antigen CD52 for developing a contraceptive vaccine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genetic analysis of fibroblast growth factor receptor 3 (FGFR3) gene that cause congenital osteochondrodysplasias.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

IgA抗精子抗体産生に関わる粘膜免疫機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Itraconazole Modulates Phospholipid Levels in Tumor-associated Macrophages2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] . Itraconazole Repolarizes Tumor-associated Macrophages and Suppresses Cervical Cancer Cell Growth.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Itraconazole Increases Resolvin E3 Concentration and 12/15-lipoxygenase Inhibitor Attenuates Itraconazole Cytotoxicity in Cervical Cancer Cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Itraconazole treatment of primary malignant melanoma of the vagina evaluated using positron emission tomography and tissue cDNA microarray: a case report2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Itraconazole Inhibits AKT/mTOR Signaling and Proliferation in Endometrial Cancer Cells.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Repurposing itraconazole as an anticancer agent: A review2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Itraconazole Modulates Hedgehog, WNT/β-catenin, as well as Akt Signalling, and Inhibits Proliferation of Cervical Cancer Cells.2017

Author(s)

Tsubamoto Hiroshi 鍔本浩志

TSUBAMOTO Hiroshi 鍔本浩志

TSUBAMOTO HIROSI 鍔本浩志