MORI Masayuki 森誠之

Researcher Number	80342640
Other IDs
Affiliation *help	2018 : 京都大学, 工学(系)研究科(研究院), 准教授 2016 : 京都大学, 工学研究科, 准教授 2015 : 京都大学, 大学院工学研究科, 准教授 2012 – 2015 : 京都大学, 工学(系)研究科(研究院), 准教授 2015 : 京都大学, 工学部, 准教授 … More
Review Section/Research Field	Principal Investigator General physiology / Functional biochemistry / Basic Section 48020:Physiology-related Except Principal Investigator General physiology
Keywords	Principal Investigator 蛍光エネルギー移動(FRET) / 平滑筋 / カルシウム / イオンチャネル / PIP2 / カルシウムシグナル / TRPチャネル / 細胞内カルシウム / イメージング / 生理学 … More Except Principal Investigator ATP / カルシウムイオン / run-down / パッチクランプ法 / カルシウムチャネル / inside-out / カルモジュリン / Cav1.2 / リン酸化 / カルシウム / 腎スリット膜複合体 / パッチクランプ / 足細胞 / 受容体刺激情報伝達 / 心筋細胞 / TRP蛋白質 / Ca情報伝達 / オカダ酸 / 糸球体硬化症 / 受容体刺激・機械刺激情報伝達 / 機械刺激情報伝達 / 細胞内カルシウム / スリット膜複合体 / Caチャネル / 濾過機能 / PKGリン酸化 Less

チャネロパシーによるカルシウム制御破綻とポドサイト機能連関Principal InvestigatorOngoing
- Principal Investigator
  
  森誠之
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Kyoto University
Lipid regulation on receptor-operated ion channels and its tuning by Ca2+Principal Investigator
- Principal Investigator
  
  Masayuki Mori
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kyoto University
Ca2+ and calmodulin-dependent inactivation of the L-type Ca2+ channel and its mutants
- Principal Investigator
  
  Minobe Etsuko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Kagoshima University
Exploration of the mechanisms underlying normal glomerular filtration function and its pathologic disruption via the TRPC6-slit diaphragm protein complex-mediated mechano-signaling
- Principal Investigator
  
  Inoue Ryuji
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Fukuoka University
Properties of the L-type Ca^channel and its mutants
- Principal Investigator
  
  MINOBE Etsuko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Kagoshima University
PIPs and Ca2+-dependent regulation on Ca channelsPrincipal Investigator
- Principal Investigator
  
  MASAYUKI Mori
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  General physiology
- Research Institution
  Kyoto University
  Fukuoka University
Regulation of L-type Ca^<2+> channel activity by calmodulin
- Principal Investigator
  
  MINOBE Etsuko
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Kagoshima University
Structural Insight for Ca channel Regulation by CalmodulinPrincipal Investigator
- Principal Investigator
  
  MORI Masayuki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Fukuoka University

All 2016 2015 2014 2013 2012 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] Screening of Transient Receptor Potential Canonical Channel Activators Identifies Novel Neurotrophic Piperazine Compounds2016
- Author(s)
  S. Sawamura, M. Hatano, Y. Takada, K. Hino, T. Kawamura, J. Tanikawa, H. Nakagawa, H. Hase, A. Nakao, M. Hirano, R. Rotrattanadumrong, S. Kiyonaka, M.X. Mori, M. Nishida, Y. Hu, R. Inoue, R. Nagata and Y. Mori
- Journal Title
  
  Mol Pharmacol
  
  Volume : 89(3) Pages : 348-363
- Peer Reviewed / Open Access / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14959, KAKENHI-PROJECT-15K18379, KAKENHI-ORGANIZER-22136001, KAKENHI-PLANNED-26111004, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-24249017, KAKENHI-PROJECT-24390054, KAKENHI-PROJECT-25293018, KAKENHI-PLANNED-26111011, KAKENHI-PROJECT-15H04678
[Journal Article] Dynamics of receptor-operated Ca(2+) currents through TRPC channels controlled via the PI(4,5)P2-PLC signaling pathway.2015
- Author(s)
  Masayuki X Mori, Kyohei Itsuki, Hideharu Hase, Seishirou Sawamura, Tatsuki Kurokawa, Yasuo Mori, Ryuji Inoue
- Journal Title
  
  Frontiers in pharmacology
  
  Volume : 6 Pages : 22-22
- Publisher
  Frontiers
- PMID
  25717302
- Year and Date
  2015-02-11
- Language
  English
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-22136001, KAKENHI-PLANNED-22136008, KAKENHI-PROJECT-24390054, KAKENHI-PROJECT-26460296, KAKENHI-PROJECT-26840032, KAKENHI-PROJECT-15H04678
[Journal Article] PLC-mediated PI(4,5)P2 hydrolysis regulates activation and inactivation of TRPC6/7 channels2014
- Author(s)
  Kyohei Itsuki, Yuko Imai, Hideharu Hase, Yasushi Okamura, Ryuji Inoue, and Masayuki Mori
- Journal Title
  
  Journal of General Physiology
  
  Volume : 143(2) Pages : 183-201
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-ORGANIZER-22136001, KAKENHI-PLANNED-22136008, KAKENHI-PROJECT-24390054, KAKENHI-PROJECT-25253016, KAKENHI-PROJECT-26861732
[Journal Article] New experimental trends for Phosphoinositides research on Ion transporter / Channel regulation2014
- Author(s)
  Masayuki X. Mori, Ryuji Inoue
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume : 126(3) Pages : 186-197
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-22136001, KAKENHI-PLANNED-22136008, KAKENHI-PROJECT-24390054
[Journal Article] Molecular determinants for cardiovascular TRPC6 channel regulation by Ca2+/calmodulin-dependent kinase II2013
- Author(s)
  Juan Shi, Naomi Geshi, Shinichi Takahashi, Shigeki Kiyonaka, Jun Ichikawa, Yaopeng Hu, Yasuo Mori, Yushi Ito, Ryuji Inoue
- Journal Title
  
  Journal of Physiology (London)
  
  Volume : 591(11) Pages : 2851-2866
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22136001, KAKENHI-PLANNED-22136008, KAKENHI-PROJECT-24390054, KAKENHI-PROJECT-24655151
[Journal Article] Novel HCN2 mutation contributes to febrile seizures by shifting the channel's kinetics in a temperature-dependent manner2013
- Author(s)
  Yuki Nakamura, Xiuyu Shi, Tomohiro Numata, Yasuo Mori, Ryuji Inoue, Christoph Lossin, Tallie Z. Baram, Shinichi Hirose
- Journal Title
  
  PLoS One
  
  Volume : 8(12)
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22136001, KAKENHI-PLANNED-22136008, KAKENHI-PROJECT-24249060, KAKENHI-PROJECT-24390054, KAKENHI-PROJECT-24590275, KAKENHI-PROJECT-24791096, KAKENHI-PUBLICLY-25129708, KAKENHI-PUBLICLY-25136708, KAKENHI-PROJECT-25670481
[Journal Article] A Self-limiting Regulation of TRPC3/C6/C7 Channels Coupled with PI(4,5)P_2-Diacylglycerol Signaling2012
- Author(s)
  Yuko Imai, Kyohei Itsuki, Yasushi Okamura, Ryuji Inoue, Masayuki X.Mori
- Journal Title
  
  Journal of Physiology, London
  
  Volume : 590 Pages : 1101-1119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590246, KAKENHI-ORGANIZER-22136001, KAKENHI-PLANNED-22136008, KAKENHI-PROJECT-22689006, KAKENHI-PROJECT-24390054, KAKENHI-PROJECT-21229003, KAKENHI-PROJECT-23650210
[Journal Article] Voltage-sensing phosphatase reveals temporal regulation of TRPC3/C6/C7 channels by membrane phosphoinositides.2012
- Author(s)
  Itsuki K, Imai Y, Okamura Y, Abe K, Inoue R, Mori MX.
- Journal Title
  
  Channels
  
  Volume : 6 Pages : 206-209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689006, KAKENHI-PROJECT-24390054, KAKENHI-PLANNED-22136008
[Journal Article] 菅忠受容体機械刺激協働による心血管Ca2+流入チャネルTRPC6の活性化増幅機構2009
- Author(s)
  井上隆司、森誠之、瓦林靖広
- Journal Title
  
  日本薬理学雑誌 134
  
  Pages : 116-121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770110
[Journal Article] Synergistic activation of vascular TRPC6 channel by receptor and mechanical stimulation via phospholipaseC/diacylglycerol and phospholipase A2/omega-hydroxylase/20-HETE pathways2009
- Author(s)
  Inoue R, Jensen LJ, Jian Z, Shi J, Hai L, Lurie AI, Henriksen FH, Salomonsson M, Morita H. Kawarabayashi Y, Mori M, Mori Y, Ito Y.
- Journal Title
  
  Circ Res. 104
  
  Pages : 1399-409
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770110
[Journal Article] 受容体機械刺激協働による心血管Ca2+流入チャネルTRPC6の活性化増幅機構2009
- Author(s)
  井上隆司、森誠之、瓦林靖広、菅忠
- Journal Title
  
  日本薬理学雑誌 134
  
  Pages : 116-121
- Data Source
  KAKENHI-PROJECT-20770110
[Journal Article] 心血管TRPチャネルを巡る病態生理の新展開2009
- Author(s)
  井上隆司、瓦林靖広、森誠之
- Journal Title
  
  心電図 29
  
  Pages : 11-21
- Data Source
  KAKENHI-PROJECT-20770110
[Journal Article] Nitric oxide cGMP protein kinase G pathway negatively regulates vascular transient receptor potential channel TRPC62008
- Author(s)
  Takahashi S, Lin H, Geshi N, Mori Y, Kawarabayashi Y, Takami N, Mori MX, Honda A, Inoue R.
- Journal Title
  
  J Physiol. 586
  
  Pages : 4209-4223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770110
[Journal Article] Crystal structure of the CaV2 IQ domain in complex with Ca2+/calmodulin : high-resolution mechanistic implications for channel regulation by Ca2+2008
- Author(s)
  Mori M. et.al.
- Journal Title
  
  Structure 16
  
  Pages : 607-620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20770110
[Presentation] Two calmodulin binding site model for the regulation of Cav1.2 channel2016
- Author(s)
  Kodai Kawaji, Etsuko Minobe, Masayuki X Mori, Masaki Kameyama
- Organizer
  日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター（北海道　札幌市）
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-25460294
[Presentation] Cav1.2型チャネルC末端遠位部切断変異体に対するカルモジュリンとATPの作用2015
- Author(s)
  蓑部悦子、森誠之、亀山正樹
- Organizer
  西日本生理学会
- Place of Presentation
  久留米大学筑水会館（福岡県　久留米市）
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-25460294
[Presentation] A FRET- and simulation-based study on the PIP2-mediated regulation of TRPC3/C6/C7 subfamily channels2015
- Author(s)
  Inoue R, Itsuki K, Imai U, Okamura Y, Mori MX
- Organizer
  Symposium “Multicellular Inputs Regulating Muscle Excitability”
- Place of Presentation
  Granlibakken, Lake Tahoe, California, USA
- Year and Date
  2015-06-14
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-24390054
[Presentation] Roles of calmodulin and the C-terminal tail ofCav1.2 channel in its activity.2010
- Author(s)
  蓑部悦子、森誠之、亀山正樹
- Organizer
  日本生理学会大会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-21790206
[Presentation] カルモジュリンをリンクさせたCav1.2型Ca^<2+>チャネルのCa^<2+>依存性調節2010
- Author(s)
  蓑部悦子、森誠之、徐建軍、亀山正樹
- Organizer
  生理学研究所研究会
- Place of Presentation
  岡崎
- Data Source
  KAKENHI-PROJECT-21790206
[Presentation] Ca^<2+> dependent modulation in calmodulin-linked Cav1.2 channels.2010
- Author(s)
  Etsuko Minobe, Masayuki Mori, Jian-jun Xu, Masaki Kameyama.
- Organizer
  The Japan-Korea Joint Symposium on Brain Sciences, and Cardiac and Smooth Muscles.
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-21790206
[Presentation] 細胞内カルシウムとCa2+チャネル-Calmodulin作用の準同時的イメージング西2009
- Author(s)
  森誠之
- Organizer
  日本生理学会
- Place of Presentation
  福岡県福岡市福岡県歯科医師会館
- Year and Date
  2009-11-07
- Data Source
  KAKENHI-PROJECT-20770110
[Presentation] カルシウムとCaチャネル-カルモジュリン相互作用の定量的同時イメージング2009
- Author(s)
  森誠之
- Organizer
  日本生化学会年会
- Place of Presentation
  兵庫県神戸市神戸国際会議場
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20770110
[Presentation] Structural basis for calmodulin-mediated Ca2+ entry channel2009
- Author(s)
  森誠之
- Organizer
  国際シンポジウム国際生理学会
- Place of Presentation
  愛知県名古屋市名古屋市立大学
- Year and Date
  2009-06-24
- Data Source
  KAKENHI-PROJECT-20770110
[Presentation] 細胞内カルシウムとCa2+チャネル-Calmodulin 作用の準同時的イメージング2009
- Author(s)
  森誠之
- Organizer
  西日本生理学会
- Place of Presentation
  福岡県福岡市福岡県歯科医師会館
- Year and Date
  2009-11-07
- Data Source
  KAKENHI-PROJECT-20770110
[Presentation] Fundamental molecular mechanism of TRPC6 channel with Calmodulin interaction2009
- Author(s)
  森誠之
- Organizer
  国際生理学会
- Place of Presentation
  京都府京都市京都国際会議場
- Year and Date
  2009-06-27
- Data Source
  KAKENHI-PROJECT-20770110
[Presentation] カルシウムとCaチャネル-カルモジュリン相互作用の定量的同時イメージング2009
- Author(s)
  森誠之
- Organizer
  日本生化学会年会
- Place of Presentation
  兵庫県神戸市神戸国際会議場
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20770110
[Presentation] Structural basis for calmodulin mediated Ca2+ entry channel国際シンポジウム2009
- Author(s)
  森誠之
- Organizer
  国際生理学会
- Place of Presentation
  愛知県名古屋市名古屋市立大学
- Year and Date
  2009-06-24
- Data Source
  KAKENHI-PROJECT-20770110
[Presentation] Fundamental molecular mechanism of TRPC6 channel with Calmodulin interaction2009
- Author(s)
  森誠之
- Organizer
  国際生理学会
- Place of Presentation
  京都府京都市京都国際会議場
- Year and Date
  2009-06-27
- Data Source
  KAKENHI-PROJECT-20770110
[Presentation] Atomic structure of Ca,2 IQ domain complexed with Ca^<2+>/calmodulin2008
- Author(s)
  Mori M., et.al.
- Organizer
  Society for Neuroscience
- Place of Presentation
  Washington D.C. (U.S.A.)(Neuroscience meeting)
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-20770110
[Presentation] Altered PIP2 sensitivity may underlie the arrhythmogenicity of mutant TRPM4 channel
- Author(s)
  Ryuji Inoue, Hu Yaopeng, Yasushi Okamura, Masayuki X Mori.
- Organizer
  第86回日本薬理学会総会・シンポジウム
- Place of Presentation
  仙台
- Invited
- Data Source
  KAKENHI-PROJECT-24390054

1. INOUE Ryuji (30232573)

# of Collaborated Projects : 3results

# of Collaborated Products : 10results
2. MINOBE Etsuko (00448581)

# of Collaborated Projects : 3results

# of Collaborated Products : 5results
3. MORI Yasuo (80212265)

# of Collaborated Projects : 2results

# of Collaborated Products : 1results
4. OKAMURA Yasushi (80201987)

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
5. KURAHARA Lin-Hai

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
6. ICHIKAWA Jun

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
7. HU Yaopeng

# of Collaborated Projects : 1results

# of Collaborated Products : 3results
8. KIOYNAKA Shigeki

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
9. Hirose Shinichi

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
10. NUMATA Tomohiro

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
11. NAKAMURA Yuki

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
12. Kurokawa Tatsuki

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
13. Motohiro Nishida

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
14. 今井裕子

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

MORI Masayuki 森 誠之

Research Projects

Research Products

Co-Researchers

チャネロパシーによるカルシウム制御破綻とポドサイト機能連関Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Lipid regulation on receptor-operated ion channels and its tuning by Ca2+Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Ca2+ and calmodulin-dependent inactivation of the L-type Ca2+ channel and its mutants

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Exploration of the mechanisms underlying normal glomerular filtration function and its pathologic disruption via the TRPC6-slit diaphragm protein complex-mediated mechano-signaling

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Properties of the L-type Ca^channel and its mutants

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

PIPs and Ca2+-dependent regulation on Ca channelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of L-type Ca^<2+> channel activity by calmodulin

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural Insight for Ca channel Regulation by CalmodulinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Screening of Transient Receptor Potential Canonical Channel Activators Identifies Novel Neurotrophic Piperazine Compounds2016

Author(s)

Journal Title

Data Source

[Journal Article] Dynamics of receptor-operated Ca(2+) currents through TRPC channels controlled via the PI(4,5)P2-PLC signaling pathway.2015

Author(s)

Journal Title

Publisher

PMID

Year and Date

Language

Data Source

[Journal Article] PLC-mediated PI(4,5)P2 hydrolysis regulates activation and inactivation of TRPC6/7 channels2014

Author(s)

Journal Title

Data Source

[Journal Article] New experimental trends for Phosphoinositides research on Ion transporter / Channel regulation2014

Author(s)

Journal Title

Data Source

[Journal Article] Molecular determinants for cardiovascular TRPC6 channel regulation by Ca2+/calmodulin-dependent kinase II2013

Author(s)

Journal Title

Data Source

[Journal Article] Novel HCN2 mutation contributes to febrile seizures by shifting the channel's kinetics in a temperature-dependent manner2013

Author(s)

Journal Title

Data Source

MORI Masayuki 森誠之