Yamazaki Yoko 山崎洋子

… Alternative Names

YAMAZAKI Yohko 山崎洋子

Less

Researcher Number	80342690
Affiliation (Current)	2025: 公益財団法人微生物化学研究会, 微生物化学研究所沼津支所, 主任研究員
Affiliation (based on the past Project Information) *help	2023: 公益財団法人微生物化学研究会, 微生物化学研究所沼津支所, 主任研究員 2022: 公益財団法人微生物化学研究会, 微生物化学研究所沼津支所, 研究員 2021 – 2022: 公益財団法人微生物化学研究会, 微生物化学研究所沼津支所, 上級研究員 2019 – 2020: 公益財団法人微生物化学研究会, 微生物化学研究所沼津支所, 研究員 2012 – 2017: 公益財団法人微生物化学研究会, 微生物化学研究所沼津支所, 研究員
Review Section/Research Field	Principal Investigator Basic Section 47050:Environmental and natural pharmaceutical resources-related / Urology
Keywords	Principal Investigator 前立腺がん / アンドロゲンレセプター / リン脂質リモデリング / 抗がん剤 / LPCAT1 / cーmyc / c-myc / 乳がん / c-Myc / 合成致死 / 前立腺癌 / 去勢抵抗性前立腺がん

細胞膜リン脂質リモデリングを標的とした新規抗がん剤の創出Principal Investigator
- Principal Investigator
  
  山崎洋子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Microbial Chemistry Research Foundation
Development of new anticancer drugs that exhibit synthetic lethal effects with c-myc on breast cancerPrincipal Investigator
- Principal Investigator
  
  YAMAZAKI Yohko
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Microbial Chemistry Research Foundation
Elucidation of androgen-dependent growth inhibition mechanism in prostate cancer of novel small molecule compound APAPrincipal Investigator
- Principal Investigator
  
  YAMAZAKI Yohko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Microbial Chemistry Research Foundation
Action mechanism elucidation of DNT, anti-prostatecancer agent from natural productsPrincipal Investigator
- Principal Investigator
  
  YAMAZAKI Yohko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Microbial Chemistry Research Foundation

All 2023 2022 2021 2020 2019 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Deoxynortryptoquivaline: A unique antiprostate cancer agent2023
- Author(s)
  Yamazaki Y, Kawada M, Momose I.
- Journal Title
  
  Oncol Res.
  
  Volume: 31 Issue: 6 Pages: 845-853
- DOI
  10.32604/or.2023.030266
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06675
[Journal Article] Androprostamine A: a unique antiprostate cancer agent2021
- Author(s)
  Yamazaki Y, Abe H, Sakashita C, Ohba SI, Watanabe T, Momose I, Kawada M.
- Journal Title
  
  J Antibiot
  
  Volume: 74 Issue: 10 Pages: 717-725
- DOI
  10.1038/s41429-021-00449-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07157, KAKENHI-PROJECT-20K07124
[Journal Article] Human pancreatic cancer cells under nutrient deprivation are vulnerable to redox system inhibition.2020
- Author(s)
  T Onodera, I Momose, H Adachi, Y Yamazaki, R Sawa, SI Ohba, M Kawada.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 295 Issue: 49 Pages: 16678-16690
- DOI
  10.1074/jbc.ra120.013893
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07157, KAKENHI-PROJECT-20K07124
[Journal Article] Leucinostatin Y: A Peptaibiotic Produced by the Entomoparasitic Fungus Purpureocillium lilacinum 40-H-28.2019
- Author(s)
  I. Momose, T. Onodera, H. Doi, H. Adachi, M. Iijima, Y. Yamazaki, R. Sawa, Y. Kubota, M. Igarashi, M. Kawada
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 印刷中 Issue: 5 Pages: 1120-1127
- DOI
  10.1021/acs.jnatprod.8b00839
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01811, KAKENHI-PROJECT-19K07157, KAKENHI-PROJECT-17K15000
[Journal Article] Synthesis of Androprostamine A and Resormycin2016
- Author(s)
  H. Abe, Y. Yamazaki, C. Sakashita, I. Momose, T. Watanabe, M. Shibasaki
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 64 Issue: 7 Pages: 982-987
- DOI
  10.1248/cpb.c16-00207
- NAID
  130005160028
- ISSN
  0009-2363, 1347-5223
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K01811, KAKENHI-PROJECT-15K10615
[Journal Article] Biological activities of unique isoflavones prepared from Apios americana Medik.2016
- Author(s)
  Kaneta H, Koda M, Saito S, Imoto M, Kawada M, Yamazaki Y, Momose I, Shindo K.
- Journal Title
  
  Biosci Biotechnol Biochem
  
  Volume: 80 Issue: 4 Pages: 774-778
- DOI
  10.1080/09168451.2015.1127132
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01811, KAKENHI-PROJECT-15K10615
[Journal Article] Androprostamines A and B, the new anti-prostate cancer agents produced by Streptomyces sp. MK932-CF8.2015
- Author(s)
  Yamazaki Y, Someno T, Igarashi M, Kinoshita N, Hatano M, Kawada M, Momose I, Nomoto A.
- Journal Title
  
  J. Antibiot.
  
  Volume: 68 Issue: 4 Pages: 279-285
- DOI
  10.1038/ja.2014.135
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23510270, KAKENHI-PROJECT-24592417, KAKENHI-PROJECT-15K01811, KAKENHI-PROJECT-15K06888
[Journal Article] Complete stereochemistry and preliminary structure-activity relationship of rakicidin A, a hypoxia-selective cytotoxin from Micromonospora sp.2014
- Author(s)
  Oku N, Matoba S, Yamazaki YM, Shimasaki R, Miyanaga S, Igarashi Y.
- Journal Title
  
  Journal of Natural Products
  
  Volume: 77 Issue: 11 Pages: 2561-2565
- DOI
  10.1021/np500276c
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592417
[Presentation] TriQuinoline(TQ)誘導体の新規合成法の開発によるG4リガンド創製及び PHAs吸着剤への応用2023
- Author(s)
  狩俣太雅、山崎洋子、Wei Xu、熊谷直哉
- Organizer
  第49回反応と合成の進歩シンポジウム
- Data Source
  KAKENHI-PROJECT-22K06675
[Presentation] 一原子欠損π平面環状分子トリキノリン誘導体DQMQzの新規合成法とその機能展開2023
- Author(s)
  狩俣太雅、Wei Xu、山崎洋子、熊谷直哉
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22K06675
[Presentation] 一原子欠損π平面環状分子トリキノリン誘導体DQMQzの新規合成法とその機能展開2023
- Author(s)
  狩俣太雅、Wei Xu、山崎洋子、熊谷直哉
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-19K07157
[Presentation] Human pancreatic cancer cells are vulnerable to inhibition of redox system under nutrient deprivation2022
- Author(s)
  I. Momose, T. Onodera, H. Adachi, Y. Yamazaki, R. Sawa, SI. Ohba and M. Kawada
- Organizer
  12th AACR-JCA Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07157
[Presentation] 神経膠芽腫由来細胞におけるErtredinによるEGFRvIIIタンパクの減少とスフェロイド形成抑制2022
- Author(s)
  渥美園子、野坂千里、川田学、小野寺威文、山崎洋子、大石智一、百瀬功、澁谷正史、内藤幹彦
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06675
[Presentation] Human pancreatic cancer cells are vulnerable to inhibition of redox system under nutrient deprivation2022
- Author(s)
  I. Momose, T. Onodera, H. Adachi, Y. Yamazaki, R. Sawa, SI. Ohba and M. Kawada
- Organizer
  12th AACR-JCA Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06675
[Presentation] Synthetic lethal approach that targets c-MYC-driven cancers2022
- Author(s)
  Y. Yamazaki, SI. Ohba, T Onodera, M. Kawada and I. Momose
- Organizer
  12th AACR-JCA Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06675
[Presentation] 前立腺がんに対する新規抗アンドロゲン薬の医薬リード創製2022
- Author(s)
  阿部光、山崎洋子、坂下千春、大庭俊一、渡辺匠、百瀬功、川田学、柴﨑正勝
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K07157
[Presentation] Synthetic lethal approach that targets c-MYC-driven cancers2022
- Author(s)
  Y. Yamazaki, SI. Ohba, T Onodera, M. Kawada and I. Momose
- Organizer
  12th AACR-JCA Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07157
[Presentation] c-Mycと合成致死作用を示す低分子化合物の探索研究2022
- Author(s)
  山崎洋子、大庭俊一、小野寺威文、川田学、百瀬功
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07157
[Presentation] c-Mycと合成致死作用を示す低分子化合物の探索研究2022
- Author(s)
  山崎洋子、大庭俊一、小野寺威文、川田学、百瀬功
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-22K06675
[Presentation] 神経膠芽腫由来細胞におけるErtredinによるEGFRvIIIタンパクの減少とスフェロイド形成抑制2022
- Author(s)
  渥美園子、野坂千里、川田学、小野寺威文、山崎洋子、大石智一、百瀬功、澁谷正史、内藤幹彦
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07157
[Presentation] AS1936: A new inhibitor of androgen receptor function in prostate cancer2017
- Author(s)
  Yohko Yamazaki, Shun-ichi Ohba, Hikaru Abe, Takumi Watanabe, Isao Momose, Manabu Kawada, Masakatsu Shibasaki
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K10615
[Presentation] Construction of screening system for new AR signaling inhibitors2016
- Author(s)
  Yohko Yamazaki, Isao Momose, Manabu Kawada, Masakatsu Shibasaki
- Organizer
  第10回日米癌合同会議
- Place of Presentation
  Hyatt Regency Maui/Maui
- Year and Date
  2016-02-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10615
[Presentation] Androprostamine A, a New Antitumor Agent for Castration Resistant Prostate Cancer2016
- Author(s)
  Yohko YAMAZAKI, Tohru MASUDA, Isao MOMOSE, Manabu KAWADA, Akio NOMOTO, Masakatsu SHIBASAKI
- Organizer
  2nd International Symposium for Medicinal Sciences
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-03-28
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10615
[Presentation] 新規抗前立腺がん物質androprostamine Aの抗腫瘍活性2015
- Author(s)
  山崎洋子　増田徹　川田学　百瀬功　柴﨑正勝
- Organizer
  第19回日本がん分子標的治療学会
- Place of Presentation
  松山全日空ホテル/松山
- Year and Date
  2015-06-12
- Data Source
  KAKENHI-PROJECT-15K10615
[Presentation] Construction of screening system for a novel AR signaling inhibitor2015
- Author(s)
  Yohko Yamazaki, Isao momose, Manabu Kawada, Masakatsu Shibasaki
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場/名古屋
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-15K10615
[Presentation] Antitumor activity of androprostamine: a new antitumor agent for castration-resistant prostate cancer2014
- Author(s)
  山崎洋子、増田徹、川田学、百瀬功、野本明男
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-24592417
[Presentation] Androprostamine: A new antitumor agent for castration-resistant prostate cancer
- Author(s)
  山崎洋子　増田徹　川田学　百瀬功　野本明男
- Organizer
  第72回日本癌学会学術集会
- Place of Presentation
  パシフィコ横浜 (横浜市)
- Data Source
  KAKENHI-PROJECT-24592417
[Presentation] Androprostamine: A new antitumor agent for androgen-dependent prostate Cancer
- Author(s)
  山崎洋子　増田徹　川田学　百瀬功　野本明男
- Organizer
  9th Joint Conference of the American Association for Cancer Research and the Japanese Cancer Association
- Place of Presentation
  ハイアットリージェンシーマウイ（アメリカ）
- Data Source
  KAKENHI-PROJECT-24592417
[Presentation] rakicidin Aの全立体構造および構造活性相関
- Author(s)
  的場翔平　奥直也　山崎洋子　嶋崎良子　宮永賢　五十嵐康弘
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  東北大学（宮城）
- Data Source
  KAKENHI-PROJECT-24592417

1. MOMOSE Isao (10270547)

# of Collaborated Projects: 3 results

# of Collaborated Products: 20 results
2. ABE Hikaru (10462269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. IIJIMA Masatomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yamazaki Yoko 山崎 洋子

YAMAZAKI Yohko 山崎 洋子

Research Projects

Research Products

Co-Researchers

細胞膜リン脂質リモデリングを標的とした新規抗がん剤の創出Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of new anticancer drugs that exhibit synthetic lethal effects with c-myc on breast cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of androgen-dependent growth inhibition mechanism in prostate cancer of novel small molecule compound APAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Action mechanism elucidation of DNT, anti-prostatecancer agent from natural productsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Deoxynortryptoquivaline: A unique antiprostate cancer agent2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Androprostamine A: a unique antiprostate cancer agent2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Human pancreatic cancer cells under nutrient deprivation are vulnerable to redox system inhibition.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Leucinostatin Y: A Peptaibiotic Produced by the Entomoparasitic Fungus Purpureocillium lilacinum 40-H-28.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthesis of Androprostamine A and Resormycin2016

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Biological activities of unique isoflavones prepared from Apios americana Medik.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Androprostamines A and B, the new anti-prostate cancer agents produced by Streptomyces sp. MK932-CF8.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Complete stereochemistry and preliminary structure-activity relationship of rakicidin A, a hypoxia-selective cytotoxin from Micromonospora sp.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] TriQuinoline(TQ)誘導体の新規合成法の開発によるG4リガンド創製及び PHAs吸着剤への応用2023

Author(s)

Organizer

Data Source

[Presentation] 一原子欠損π平面環状分子トリキノリン誘導体DQMQzの新規合成法とその機能展開2023

Author(s)

Organizer

Data Source

Yamazaki Yoko 山崎洋子

YAMAZAKI Yohko 山崎洋子