Muto Akihiko 武藤哲彦

… Alternative Names

MUTO Akihiko 武藤哲彦

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Researcher Number	80343292
Other IDs
Affiliation (Current)	2025: 東北大学, 医学系研究科, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2022: 東北大学, 医学系研究科, 准教授 2016 – 2019: 東北大学, 医学系研究科, 准教授 2011 – 2015: 東北大学, 医学(系)研究科(研究院), 准教授 2014: 東北大学, 大学院医学系研究科, 准教授 2011 – 2012: 東北大学, 大学院・医学系研究科, 准教授 … More 2009 – 2010: Tohoku University, 大学院・医学系研究科, 講師 2008: 東北大学, 大学院・医学系研究科, 教授 2007 – 2008: Tohoku University, 大学院・医学系研究科, 助教 2006: 東北大学, 大学院医学系研究科, 助教 2005 – 2006: 東北大学, 大学院医学系研究科, 助手 2005: 東北大学, 大学院・医学系研究科, 助手 2002 – 2004: 広島大学, 大学院・医歯薬学総合研究科, 助手 Less
Review Section/Research Field	Principal Investigator General medical chemistry / Biological Sciences / Biological Sciences / Basic Section 49070:Immunology-related / Basic Section 43010:Molecular biology-related / General medical chemistry Except Principal Investigator General medical chemistry / Biophysics / Biological Sciences / Pathological medical chemistry
Keywords	Principal Investigator B細胞 / 転写因子 / Bach2 / 遺伝子 / 免疫学 / 形質細胞 / クラススイッチ / 発現制御 / Blimp-1 / ノックアウトマウス … More / シングルセル / 活性酸素シグナル / Bリンパ球 / 転写制御 / 癌 / マイクロアレイ / AP-1 / 鉄代謝 / プロテオーム / 細胞増殖 / 胚中心 / B cell / ユビキチン / ヘム / Pax5 / 造血幹細胞 / 細胞分化 / 細胞医化学 / 形質細胞分化 / ネットワーク / 免疫 / 抗体 / 癌遺伝子 / XBP-1 / AID / 発現抑制 / レトロウィルス / 酸化ストレス … More Except Principal Investigator Bach1 / 転写因子 / 酸化ストレス / oxidative stress / heme / transcription factor / ストレス / 蛋白質 / 免疫学 / 遺伝子 / 発現制御 / クロマチン / Bach2 / ヘム / proteasome / ubiquitin / cellular senescence / プロテアソーム / ユビキチン / 細胞老化 / Maf / B cell / globin / ヒストン / ピストン / Bリンパ球 / 赤血球 / グロビン / X線小角散乱 / 構造変化 / ヘム結合 / 天然変性タンパク質 / タンパク質構造変化 / 発生分化 / 蛍光蛋白質 / ヘムオキシゲナーゼ Less

B細胞免疫応答における鉄代謝制御と機能の解明Principal Investigator
- Principal Investigator
  
  武藤哲彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Tohoku University
Elucidation of diverse response mechanisms of activated B cells by single cell analysisPrincipal Investigator
- Principal Investigator
  
  MUTO Akihiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Tohoku University
Analysis of Bach2 expression level-dependent regulation of B cell immune responsePrincipal Investigator
- Principal Investigator
  
  Muto Akihiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
Analysis of regulatory process of plasma cell differentiation by gene regulatory networksPrincipal Investigator
- Principal Investigator
  
  Muto Akihiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
Regulation of Bach2 intrinsically disordered region by ligand
- Principal Investigator
  
  MURAYAMA Kazutaka
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Tohoku University
活性酸素シグナルによる液性免疫制御因子Ｂａｃｈ２の活性調節機構の解明Principal Investigator
- Principal Investigator
  
  武藤哲彦
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Elucidation of physiological role of the Bach2 ubiquitinationPrincipal Investigator
- Principal Investigator
  
  MUTO Akihiko
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
転写因子Bach2をハブとする活性酸素シグナル-遺伝子ネットワーク共役機構の解明Principal Investigator
- Principal Investigator
  
  武藤哲彦
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Regulation of immune cell responses by heme
- Principal Investigator
  
  IGARASHI Kazuhiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
Analysis of regulatory mechanism of early B cell development by Bach transcriptional factorsPrincipal Investigator
- Principal Investigator
  
  MUTO Akihiko
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
Functional analysis of Bach2 target genes.Principal Investigator
- Principal Investigator
  
  MUTO Akihiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
転写因子Bach2によるB細胞増殖調節機構の解析Principal Investigator
- Principal Investigator
  
  武藤哲彦
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
転写因子Bach2によるB細胞増殖関連遺伝子の調節機構の解明Principal Investigator
- Principal Investigator
  
  武藤哲彦
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
転写因子Bach2によるB細胞活性化応答遺伝子プログラムの解明Principal Investigator
- Principal Investigator
  
  武藤哲彦
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Comparative Analysis of the DECODE Systems in Hematopoiesis and Oxidative Stress Response
- Principal Investigator
  
  IGARASHI Kazuhiko
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Control of cell proliferation and differentiation by heme bindiny transcription factor Bachl
- Principal Investigator
  
  IGARASHI Kazuhiko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
転写因子Bach2遺伝子ノックアウトマウスを用いたB細胞活性化調節機構の解析Principal Investigator
- Principal Investigator
  
  武藤哲彦
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
  Hiroshima University
ヘムオキシゲナーゼ1制御因子を標的とした虚血再潅流病態改善薬探索システムの開発
- Principal Investigator
  
  IGARASHI Kazuhiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Hiroshima University
Regulation of hematopoiesis by the transcription factors Bach1 and Bach2
- Principal Investigator
  
  IGARASHI Kazuhiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Hiroshima University
Bach2ノックアウトマウスを用いたB細胞分化調節機構の解明Principal Investigator
- Principal Investigator
  
  武藤哲彦
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Hiroshima University

[Journal Article] Heme-dependent induction of mitophagy program during differentiation of murine erythroid cells2023
- Author(s)
  Ikeda Masatoshi、Kato Hiroki、Shima Hiroki、Matsumoto Mitsuyo、Furukawa Eijiro、Yan Yan、Liao Ruiqi、Xu Jian、Muto Akihiko、Fujiwara Tohru、Harigae Hideo、Bresnick Emery H.、Igarashi Kazuhiko
- Journal Title
  
  Experimental Hematology
  
  Volume: 118 Pages: 21-30
- DOI
  10.1016/j.exphem.2022.11.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07129, KAKENHI-PROJECT-22H00443, KAKENHI-PROJECT-20K07321, KAKENHI-PROJECT-21K20770, KAKENHI-PROJECT-21K08385, KAKENHI-PROJECT-22K16295, KAKENHI-PROJECT-23K24156
[Journal Article] Infection perturbs Bach2- and Bach1-dependent erythroid lineage chioce to cause anemia2018
- Author(s)
  Kato H, Itoh-Nakadai A, Matsumoto M, Ishii Y, Watanabe-Matsui M, Ikeda M, Ebina-Shibuya R, Sato Y, Kobayashi M, Nishizawa H, Suzuki K, Muto A, Fujiwara T, Nannya Y, Cazzola M, Ogawa S, Harigae H, Igarashi K
- Journal Title
  
  Nat Immunol
  
  Volume: 19 Issue: 10 Pages: 496-497
- DOI
  10.1038/s41590-018-0202-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08314, KAKENHI-PROJECT-26221308, KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-16K07108, KAKENHI-PROJECT-16J40189, KAKENHI-PROJECT-16K08572
[Journal Article] Bach2 Promotes B Cell Receptor?Induced Proliferation of B Lymphocytes and Represses Cyclin-Dependent Kinase Inhibitors2018
- Author(s)
  Miura Yuichi、Morooka Mizuho、Sax Nicolas、Roychoudhuri Rahul、Itoh-Nakadai Ari、Brydun Andrey、Funayama Ryo、Nakayama Keiko、Satomi Susumu、Matsumoto Mitsuyo、Igarashi Kazuhiko、Muto Akihiko
- Journal Title
  
  J Immunol
  
  Volume: - Issue: 8 Pages: 2882-2893
- DOI
  10.4049/jimmunol.1601863
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-16K07108, KAKENHI-PROJECT-16K08572
[Journal Article] A Bach2-Cebp gene regulatory network for the commitment of multipotent hematopoietic progenitors.2017
- Author(s)
  Itoh-Nakadai, A., Matsumoto, M., Kato, H., Sasaki, J., Uehara, Y., Sato, Y., Ebina-Shibuya, R., Morooka, M., Funayama, R., Nakayama, K., Ochiai, K., Muto, A. and Igarashi, K.
- Journal Title
  
  Cell Reports
  
  Volume: 18 Issue: 10 Pages: 2401-2414
- DOI
  10.1016/j.celrep.2017.02.029
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-26293059, KAKENHI-PROJECT-16K14664, KAKENHI-PROJECT-15K18998, KAKENHI-PROJECT-16K08572, KAKENHI-PROJECT-16K07108, KAKENHI-PROJECT-15KK0328
[Journal Article] S -Adenosylmethionine Synthesis Is Regulated by Selective N 6 -Adenosine Methylation and mRNA Degradation Involving METTL16 and YTHDC12017
- Author(s)
  Shima Hiroki、Matsumoto Mitsuyo、Ishigami Yuma、Ebina Masayuki、Muto Akihiko、Sato Yuho、Kumagai Sayaka、Ochiai Kyoko、Suzuki Tsutomu、Igarashi Kazuhiko
- Journal Title
  
  Cell Rep.
  
  Volume: 21 Issue: 12 Pages: 3354-3363
- DOI
  10.1016/j.celrep.2017.11.092
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08572, KAKENHI-PROJECT-17K07278, KAKENHI-PROJECT-26220205, KAKENHI-PLANNED-26113003
[Journal Article] Iron-heme-Bach1 axis is involved in erythroblast adaptation to iron deficiency.2017
- Author(s)
  Kobayashi M, Kato H, Hada H, Itoh-Nakadai A, Fujiwara T, Muto A, Inoguchi Y, Ichiyanagi K, Hojo W, Tomosugi N, Sasaki H, Harigae H, Igarashi K.
- Journal Title
  
  Haematologica
  
  Volume: 102 Issue: 3 Pages: 454-465
- DOI
  10.3324/haematol.2016.151043
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293225, KAKENHI-PROJECT-16K08572, KAKENHI-PROJECT-15H02506
[Journal Article] Inflammatory responses induce an identity crisis of alveolar macrophages, leading to pulmonary alveolar proteinosis.2017
- Author(s)
  Ebina-Shibuya R, Matsumoto M, Kuwahara M, Jang KJ, Sugai M, Ito Y, Funayama R, Nakayama K, Sato Y, Ishii N, Okamura Y, Kinoshita K, Kometani K, Kurosaki T, Muto A, Ichinose M, Yamashita M, Igarashi K.
- Journal Title
  
  The Journal of biological chemistry
  
  Volume: 292 Issue: 44 Pages: 18098-18112
- DOI
  10.1074/jbc.m117.808535
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07108, KAKENHI-PROJECT-16K08572, KAKENHI-PROJECT-16K15232, KAKENHI-PROJECT-26221306, KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-15H04742, KAKENHI-PROJECT-16H05138, KAKENHI-PROJECT-16H05307, KAKENHI-PROJECT-17H04035, KAKENHI-PROJECT-16H06640, KAKENHI-PROJECT-16K15289, KAKENHI-PROJECT-16K15508, KAKENHI-PROJECT-16K19158
[Journal Article] The transcription factor Bach2 is phosphorylated at multiple sites in murine B cells but a single site prevents its nuclear localization2016
- Author(s)
  Ando R, Shima H, Tamahara T, Sato Y, Watanabe-Matsui M, Kato H, Sax N, Motohashi H, Taguchi K, Yamamoto M, Nio M, Maeda T, Ochiai K, Muto A, Igarashi K
- Journal Title
  
  J Biol Chem
  
  Volume: 291 Issue: 4 Pages: 1826-1840
- DOI
  10.1074/jbc.m115.661702
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23116002, KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-25460352, KAKENHI-PROJECT-26670150, KAKENHI-PROJECT-25291042, KAKENHI-WRAPUP-16H01688, KAKENHI-PROJECT-16J40189
[Journal Article] Epigenetic Regulation of the Blimp-1 Gene (Prdm1) in B Cells Involves Bach2 and Histone Deacetylase 3*2016
- Author(s)
  Tanaka H
- Journal Title
  
  JBC
  
  Volume: 291 Issue: 12 Pages: 6316-6330
- DOI
  10.1074/jbc.m116.713842
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K12203, KAKENHI-PLANNED-23116003, KAKENHI-PUBLICLY-26114723, KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-25460351, KAKENHI-PROJECT-25460352, KAKENHI-PROJECT-25650014, KAKENHI-PROJECT-26281020, KAKENHI-PROJECT-15K07164, KAKENHI-PROJECT-26251004, KAKENHI-PROJECT-16K14675
[Journal Article] BACH2 regulates CD8+ T cell differentiation by controlling access of AP-1 factors to enhancers.2016
- Author(s)
  Roychoudhuri, R., Clever, D., Li, P., Wakabayashi, Y., Quinn, K.M., Klebanoff, C.A., Ji, Y., Sukumar, M., Eil, R.L., Yu, Z., Spolski, R., Palmer, D.C., Pan, J.H., Patel, S.J., Macallan, D.C., Fabozzi, G., Shih, H.Y., Kanno, Y., Muto, A., Igarashi, K., Leonard, W.J., and Restifo, N.P.
- Journal Title
  
  Nature Immunology
  
  Volume: 17 Issue: 7 Pages: 851-860
- DOI
  10.1038/ni.3441
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02506, KAKENHI-PROJECT-16K08572
[Journal Article] The double knockout of Bach1 and Bach2 in mice reveals shared compensatory mechanisms in regulating alveolar macrophage function and lung surfactant homeostasis.2016
- Author(s)
  Ebina-Shibuya R, Watanabe-Matsui M, Matsumoto M, Itoh-Nakadai A, Funayama R, Nakayama K, Muto A, Igarashi K.
- Journal Title
  
  J Biochem.
  
  Volume: 160 Pages: 333-344
- NAID
  40021050454
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08572
[Journal Article] Mitochondrial function provides instructive signals for activation-induced B cell fates2015
- Author(s)
  Kyoung-Jin Jang, Hiroto Mano, Koji Aoki, Tatsunari Hayashi, Yukiko Nambu, Eri Hara, Katsu Takahashi, Katsuhiko Itoh, Shigeru Taketani, Kazuhiko Igarashi, Akira Shimizu and Manabu Sugai
- Journal Title
  
  Nature Commun
  
  Volume: 6 Issue: 1 Pages: 6750-6750
- DOI
  10.1038/ncomms7750
- NAID
  120005595832
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25463081, KAKENHI-PROJECT-25460352, KAKENHI-PROJECT-25293069, KAKENHI-PROJECT-24680091
[Journal Article] Heme binds to an intrinsically disordered region of Bach2 and alters its conformation2014
- Author(s)
  M. Watanabe-Matsui, T. Matsumoto, T. Matsui, M. Ikeda-Saito, A. Muto, K. Murayama, and K. Igarashi
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 565巻 Pages: 25-31
- DOI
  10.1016/j.abb.2014.11.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24120001, KAKENHI-PROJECT-24350081, KAKENHI-PROJECT-24570175, KAKENHI-PUBLICLY-25109504, KAKENHI-PROJECT-25460352, KAKENHI-PROJECT-25860203, KAKENHI-PROJECT-15H02506
[Journal Article] Association between BACH2 expression and clinical prognosis in diffuse large B-cell lymphoma.2014
- Author(s)
  Ichikawa, S., Fukuhara, N., Katsushima, H., Takahashi, T., Yamamoto, J., Yokoyama, H., Sasaki, O., Fukuhara, O., Nomura, J., Ishizawa, K., Ichinohasama, R., Muto, A., Igarashi, K., and Harigae, H.
- Journal Title
  
  Cancer Science
  
  Volume: in press Issue: 4 Pages: 437-444
- DOI
  10.1111/cas.12361
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-24590677, KAKENHI-PROJECT-25460352, KAKENHI-PROJECT-26870038
[Journal Article] The transcription repressors Bach2 and Bach1 promote B cell development by repressing myeloid program.2014
- Author(s)
  Itoh-Nakadai A, Hikota R, Muto A, Kometani K, Matsui-Watanabe M, Sato Y, Kobayashi M, Nakamura A, Miura Y, Yano Y, Tashiro S, Sun J, Ikawa T, Ochiai K, Kurosaki T, and Igarashi K.
- Journal Title
  
  Nature Immunol.
  
  Volume: 15 Issue: 12 Pages: 1171-1180
- DOI
  10.1038/ni.3024
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-24689042, KAKENHI-PUBLICLY-25118732, KAKENHI-PROJECT-25460352, KAKENHI-PUBLICLY-26116514, KAKENHI-PROJECT-26293229, KAKENHI-PROJECT-26430114, KAKENHI-PROJECT-26670472
[Journal Article] Bach2 represses effector programmes to stabilize Treg-mediated immune homeostasis.2013
- Author(s)
  Roychoudhuri, R., Hirahara, K., Mousavi, K., Clever, D., Klebanoff, C. A., Bonelli, M., Sciume, G., Zare, H., Vahedi, G., Dema, B., Yu, Z., Liu, H., Takahashi, H., Rao, M., Muranski, P., Crompton, J. G., Punkosdy, G., Muto, A., Igarashi, K., et al.
- Journal Title
  
  Nature
  
  Volume: 498 Issue: 7455 Pages: 506-510
- DOI
  10.1038/nature12199
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-25460352
[Journal Article] Transcriptional suppression of BACH2 by the Bcr-Abl oncoprotein is mediated by PAX5.2013
- Author(s)
  Casolari DA
- Journal Title
  
  Leukemia.
  
  Volume: 27(2) Issue: 2 Pages: 409-415
- DOI
  10.1038/leu.2012.220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790322, KAKENHI-PUBLICLY-23117702
[Journal Article] BTB and CNC Homolog 1 (Bach1) Deficiency Ameliorates TNBS Colitis in Mice: Role of M2 Macrophages and Heme Oxygenase-12013
- Author(s)
  Harusato, A. Naito, Y. Takagi, T. Uchiyama, K. Mizushima, K. Hirai, Y. Higashimura, Y. Katada, K. Handa, O. Ishikawa, T. Yagi, N. Kokura, S. Ichikawa, H. Muto, A. Igarashi, K. Yoshikawa, T.
- Journal Title
  
  Inflamm Bowel Dis
  
  Volume: 19 Issue: 4 Pages: 740-753
- DOI
  10.1097/mib.0b013e3182802968
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590705, KAKENHI-PROJECT-22590706, KAKENHI-PROJECT-23790322, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-25460959, KAKENHI-PUBLICLY-23117702
[Journal Article] Over-expression of BACH2 is related to ongoing somatic hypermutation of the immunoglobulin heavy chain gene variable region of de novo diffuse large B-cell lymphoma.2013
- Author(s)
  Kikuchi T, Tokunaka M, Kikuti YY, Carreras J, Ogura G, Takekoshi S, Kojima M, Ando K, Hashimoto Y, Abe M, Takata K, Yoshino T, Muto A, Igarashi K, Nakamura N.
- Journal Title
  
  Pathol Int
  
  Volume: 63 Issue: 7 Pages: 339-344
- DOI
  10.1111/pin.12076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790350, KAKENHI-PROJECT-25460352
[Journal Article] Bach2 maintains T cells in a naive state by suppressing effector memory-related genes2013
- Author(s)
  Tsukumo, S., Unno, M., Muto, A., Takeuchi, A., Kometani, K., Kurosaki, T., Igarashi, K., Saito, T
- Journal Title
  
  Proc. Natl. Acad. Sci. U. S. A.
  
  Volume: 110 Issue: 26 Pages: 10735-40
- DOI
  10.1073/pnas.1306691110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229007, KAKENHI-PLANNED-23116003, KAKENHI-PROJECT-24229004, KAKENHI-PROJECT-24390066, KAKENHI-PROJECT-25460352
[Journal Article] Bach1 regulates osteoclastogenesis via both heme oxygenase-1 dependent and independent pathways2012
- Author(s)
  Maasa Hama, Yohei Kirino, Mitsuhiro Takeno, Kaoru Takase, Takuya Miyazaki, Ryusuke Yoshimi, Atsuhisa Ueda, Ari Itoh-Nakadai, Akihiko Muto, Kazuhiko Igarashi, Yoshiaki Ishigatsubo
- Journal Title
  
  American Rheumatism Association
  
  Volume: (In press) Issue: 5 Pages: 1518-28
- DOI
  10.1002/art.33497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J07369, KAKENHI-PUBLICLY-23117702, KAKENHI-PROJECT-23591443, KAKENHI-PROJECT-23790322, KAKENHI-PROJECT-24791001
[Journal Article] Heme regulates B cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach22011
- Author(s)
  Watanabe-Matsui, M., Muto, A., Matsui, T., Itoh-Nakadai, A., Nakajima, O., Murayama, K., Yamamoto, M., Ikeda-Saito, M., Igarashi, K.
- Journal Title
  
  Blood
  
  Volume: 117巻 Pages: 5438-5448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249014
[Journal Article] Structure and dynamics of gene regulatory network for humoral immune response2011
- Author(s)
  Muto A, Itoh-Nakadai A, Igarashi K.
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 52(6) Pages: 376-386
- NAID
  10029425244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790322
[Journal Article] Heme regulates B-cecll differentiation, antibody class swotch, and heme oxygenase-1 expression in B cells as a ligand of Bach22011
- Author(s)
  Miki Watanabe-Matsui, Akihiko Muto, Toshitaka Matusi, Ari Itoh-Nakadai, Nakajima Osamu, Kazutaka Murayama, Masayuki Yamamoto, Masao Ikeda-Saito, Kazuhiko Igarashi
- Journal Title
  
  Blood In press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790261
[Journal Article] Structure and dynamics of gene regulatory network for humoral immune response2011
- Author(s)
  Muto A, Itoh-Nakadai A, Igarashi K.
- Journal Title
  
  Rinsho Ketsueki.
  
  Volume: 52 Pages: 376-386
- NAID
  10029425244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790322
[Journal Article] Heme regulates B-cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach22011
- Author(s)
  Watanabe-Matsui M
- Journal Title
  
  Blood
  
  Volume: 117 Issue: 20 Pages: 5438-48
- DOI
  10.1182/blood-2010-07-296483
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22118002, KAKENHI-PUBLICLY-23117702, KAKENHI-PROJECT-23790320, KAKENHI-PROJECT-23790322
[Journal Article] Structure and dynamics of gene regulatory network for humoral immune response2011
- Author(s)
  Muto A., Itoh-Nakadai A., Igarashi K.
- Journal Title
  
  Rinsho Ketueki
  
  Volume: 52 Pages: 376-386
- NAID
  10029425244
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23117702
[Journal Article] Suppression of indomethacin-induced apoptosis in the small intestine due to Bach1 deficiency2011
- Author(s)
  Harusato A, Naito Y, Takagi T, Uchiyama K, Mizushima K, Hirai Y, Yamada S, Tuji T, Yoriki H, Horie R, Inoue K, Fukumoto K, Handa O, Ishikawa T, Kokura S, Minamiyama Y, Ichikawa H, Muto A, Igarashi K, Yoshikawa T
- Journal Title
  
  Free Radic Res
  
  Volume: 45(6) Issue: 6 Pages: 717-727
- DOI
  10.3109/10715762.2011.574287
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500767, KAKENHI-PROJECT-22590706, KAKENHI-PUBLICLY-23117702, KAKENHI-PROJECT-23790322
[Journal Article] Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch2010
- Author(s)
  Muto, A., 他
- Journal Title
  
  EMBO J.
  
  Volume: 29 Pages: 4048-4061
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21117503
[Journal Article] Bach1-dependent and-independent regulation of heme oxygenase-1 in leratinocytes2010
- Author(s)
  S.Okada, A.Muto, E.Ogawa, A.Nakanome, Y.Katoh, S.Ishikawa, S.Aiba, K.Igarashi, R.Okuyama
- Journal Title
  
  J.Biol.Chem. vol.285
  
  Pages: 23581-23589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790261
[Journal Article] Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch2010
- Author(s)
  Muto, A., Ochiai, K., Kimura, Y., Itoh-Nakadai, A., Calame, K. L., Ikebe, D., Tashiro, S. and Igarashi, K.
- Journal Title
  
  EMBO J.
  
  Volume: 29巻 Pages: 4048-4061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249014
[Journal Article] Bach2 represses plasma cell gene regulatory network in B cell to promote antibody class switch2010
- Author(s)
  Akihiko Muto, Kyoko Ochiai, Yoshitaka Kimura, Ari Itoh-Nakadai, Kyatharin Calame, Dai Ikebe, Satoshi Tashiro, Kazuhiko Igarashi
- Journal Title
  
  EMBO J. vol.29
  
  Pages: 4048-4061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790261
[Journal Article] Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch2010
- Author(s)
  Muto, A., 他
- Journal Title
  
  EMBO J.
  
  Volume: 29 Pages: 4048-4061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790261
[Journal Article] Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch2010
- Author(s)
  Muto, A., Ochiai, K., Kimura, Y., Itoh-Nakadai, A., Calame, K.L., Ikebe, D., Tashiro, S., Igarashi, K.
- Journal Title
  
  EMBO J
  
  Volume: 29 Pages: 4048-4061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249014
[Journal Article] Bach1-dependent and -independent regulation of heme oxygenase-1 in keratinocytes.2010
- Author(s)
  Okada, S., Muto, A., Ogawa, E., Nakanome, A., Katoh, Y., Ikawa, S., Aiba, S., Igarashi, K., Okuyama, R
- Journal Title
  
  J. Biol. Chem (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054028
[Journal Article] Inhibition of Bach1 ameliorates indomethacin-induced intestinal injyry in mice2009
- Author(s)
  A.Harusato, Y.naito, T.Takagi, S.Yamada, K.Mizushima, Y.Hirai, R.Horie, K.Inoue, K.Fukumoto, I.Hirata, T.Omatsu, E.Kishimoto, K.Uchiyama, O.Haneda, T.Ishikawa, S.Kokura, H.Ichikawa, A.Muto, K.Igarashi, T.Yoshikawa
- Journal Title
  
  J.Physiol.Pharmacol. vol.7
  
  Pages: 149-154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790261
[Journal Article] Regulation of the plasma cell transcription factor Blimp-1 gene by Bach2 and Bcl62008
- Author(s)
  Ochiai, K., Muto, A., Tanaka, H., Takahashi, S., and Igarashi, K.
- Journal Title
  
  Int. Immunol vol.20
  
  Pages: 435-460
- NAID
  10021240257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790202
[Journal Article] Bach1 inhibits oxidative stress-induced cellular senescence by impeding p53 function on chromatin.2008
- Author(s)
  Dohi, Y., Ikura, T., Hoshikawa, Y., Katoh, Y., Ota, K., Nakanome, A., Muto, A., Omura, S., Ohta, T., Ito, A., Yoshida, M., Noda, T., Igarashi, K
- Journal Title
  
  Nature Struct. Mol. Biol 15
  
  Pages: 1246-1254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054028
[Journal Article] Bach1 inhibits oxidative stress-induced cellular senescence by impeding p53 function on chromatin2008
- Author(s)
  Dohi, Y., Ikura, T., Hoshikawa, Y., Katoh, Y., Ota, K., Nakanome, A., Muto, A., Omura, S., Ohta T., Ito, A., Yoshida, M., Noda, T., and Igarashi, K.
- Journal Title
  
  Nature Struct. Mol. Biol. vol.15
  
  Pages: 1246-1254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790202
[Journal Article] The mobility of Bach2 nuclear foci is regulated by SUMO-1 modification.2008
- Author(s)
  Kono, K., Harano, Y., Hoshino, H., Kobayashi, M., Bazett-Jones, DP., Muto, A., Igarashi, K., and Tashiro, S.
- Journal Title
  
  Exp Cell Res. vol.314
  
  Pages: 903-913
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790202
[Journal Article] Regulation of the plasma cell transcription factor Blimp-1 gene by Bach2 and Bcl6.2008
- Author(s)
  Ochiai, K., Muto, A., Tanaka, H., Takahashi, S., Igarashi, K
- Journal Title
  
  Int. Immunol 20
  
  Pages: 453-460
- NAID
  10021240257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054028
[Journal Article] DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics2007
- Author(s)
  Ikura, T., Tashiro, S., Kakino, A., Shima, H., Jacob, N., Amunugama, R., Yoder, K., Izumi, S., Kuraoka, I., Tanaka, K., Kimura, H., Ikura, M., Nishikubo, S., Ito, T., Muto, A., Miyagawa, S., Takeda, S., Fishel, R., Igarashi, K., and Kaiyha, K.
- Journal Title
  
  Mol. Cell. Biol. vol.27
  
  Pages: 7028-7040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790202
[Journal Article] Architecture and dynamics of the transcription factor network that regulates B-to-Plasma cell differentiation2007
- Author(s)
  Igarashi, K., Ochiai, K., and Muto, A.
- Journal Title
  
  J. Biochem, vol.141
  
  Pages: 738-789
- NAID
  10020098307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790202
[Journal Article] B細胞-形質細胞分化における転写因子Bach2の機能2006
- Author(s)
  落合恭子, 武藤哲彦, 五十嵐和彦
- Journal Title
  
  遺伝子医学MOOK 6号
  
  Pages: 75-79
- Data Source
  KAKENHI-PROJECT-18012006
[Journal Article] Plasmacytic transcription factor Blimp-1 is repressed by Bach2 in B cells.2006
- Author(s)
  Ochiai, K., Katoh, Y., Ikura, T., Hoshikawa, Y., Noda, T., Karasuyama, H., Tashiro, S., Muto, A., Igarashi, K
- Journal Title
  
  J. Biol. Chem 281
  
  Pages: 38226-38234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17054028
[Journal Article] The transcriptional programme of antibody class switching involves the repressor Bach2.2004
- Author(s)
  Muto, A.
- Journal Title
  
  Nature 429
  
  Pages: 566-571
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390095
[Journal Article] The transcriptional programme of antibody class switching involves the repressor Bach2.2004
- Author(s)
  Muto, A., et al.
- Journal Title
  
  Nature 429
  
  Pages: 566-571
- Data Source
  KAKENHI-PROJECT-16790171
[Journal Article] The transcriptional programme of antibody class switching involves the repressor Bach22004
- Author(s)
  Muto, A.
- Journal Title
  
  Nature 429
  
  Pages: 566-571
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390095
[Presentation] The dynamics of essential trace element metabolism in B cell immune response2023
- Author(s)
  武藤哲彦
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07129
[Presentation] Induction of essential trace element transporter influences B cell immune response2021
- Author(s)
  武藤哲彦
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19K06480
[Presentation] The activated B cell fate decision is regulated by fluctuated expressions of Bach22019
- Author(s)
  武藤哲彦
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19K06480
[Presentation] 転写因子の発現量のゆらぎに基づく細胞運命決定メカニズム2019
- Author(s)
  武藤哲彦
- Organizer
  日本遺伝学会第91回大会
- Data Source
  KAKENHI-PROJECT-19K06480
[Presentation] Bach2 expression level is a key driver of B cell fate decision2019
- Author(s)
  Akihiko Muto
- Organizer
  Interdisciplinary seminar on mucosal immunology at Tohoku University
- Invited
- Data Source
  KAKENHI-PROJECT-16K08572
[Presentation] 活性化B細胞の多様な応答機構のシングルセル解析2019
- Author(s)
  武藤哲彦
- Organizer
  19回日本蛋白質科学会年会第71回日本細胞生物学会大会合同年次大会
- Data Source
  KAKENHI-PROJECT-19K06480
[Presentation] Single-cell Analysis of Bach2 Function in Immune Responses2019
- Author(s)
  Akihiko Muto
- Organizer
  6th Symposium S.A.R.C. in collaboration with open innovation strategy organization Tohoku university
- Invited
- Data Source
  KAKENHI-PROJECT-16K08572
[Presentation] 転写因子Bach2量によるB細胞分化制御のシングルセル解析2018
- Author(s)
  武藤哲彦
- Organizer
  AMED-CRESTエピゲノム領域 H29年度領域会議
- Data Source
  KAKENHI-PROJECT-16K08572
[Presentation] Influence of Bach2 expression levels on activated-B cell fate decision2018
- Author(s)
  Akihiko Muto, Nicolas Sax, Shuto Fushimi, Mitsuyo Matsumoto, Kazuhiko Igarashi
- Organizer
  第47回　日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08572
[Presentation] 活性化B細胞における遺伝子ネットワークのシングルセル解析2017
- Author(s)
  武藤哲彦、Nicolas Sax、伏見修人、松本光代、五十嵐和彦
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08572
[Presentation] 活性化B細胞の遺伝子ネットワークのシングルセル解析2016
- Author(s)
  Akihiko Muto, Sax Nicolas, Mitsuyo Matsumoto, Kazuhiko Igarashi
- Organizer
  第89回　日本生化学会大会
- Place of Presentation
  仙台市　東北大学
- Data Source
  KAKENHI-PROJECT-16K08572
[Presentation] 活性化B細胞の多様化と形質細胞分化を調節する Bach2遺伝子ネットワークの解明2016
- Author(s)
  武藤哲彦
- Organizer
  日本生化学会　東北支部　第82回例会
- Place of Presentation
  弘前市　弘前大学
- Invited
- Data Source
  KAKENHI-PROJECT-16K08572
[Presentation] 天然変性ハブタンパク質Bach2のヘムによる制御2016
- Author(s)
  武藤哲彦
- Organizer
  よこはまNMR研究会第54回ワークショップ
- Place of Presentation
  横浜（理化学研究所横浜事業所　交流棟ホール）
- Year and Date
  2016-01-08
- Invited
- Data Source
  KAKENHI-PROJECT-25460352
[Presentation] B細胞活性化応答を制御する遺伝子ネットワークのシングルセル解析2015
- Author(s)
  武藤哲彦
- Organizer
  RIMS研究集会「生物現象におけるパターン形成と数理」
- Place of Presentation
  京都（京都大学　数理解析研究所）
- Year and Date
  2015-10-21
- Invited
- Data Source
  KAKENHI-PROJECT-25460352
[Presentation] Bach2の発現量が活性化B細胞の運命を決定する2014
- Author(s)
  武藤哲彦、落合恭子、黒崎知博、五十嵐和彦
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  神奈川県　横浜市　パシフィコ横浜
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-25460352
[Presentation] B細胞レセプターシグナルによる細胞増殖と生存応答でのBach2の役割2014
- Author(s)
  武藤哲彦、三浦佑一、諸岡瑞穂、五十嵐和彦
- Organizer
  冬の若手ワークショップ2014
- Place of Presentation
  群馬県、安中市
- Data Source
  KAKENHI-PROJECT-25460352
[Presentation] Bach2 and HDAC3 repress Blimp-1 gene expression in B cells through the histone deacetylation2014
- Author(s)
  武藤哲彦、田中　拡、落合恭子、加藤恭丈、仁尾正記、五十嵐和彦
- Organizer
  Cold Spring Harbor Asia Conference: Frontiers of Immunology in Health and Diseases
- Place of Presentation
  Suzhou, China（蘇州、中国）
- Year and Date
  2014-09-02
- Data Source
  KAKENHI-PROJECT-25460352
[Presentation] Bach2の発現量による活性化B細胞の運命決定2014
- Author(s)
  武藤哲彦
- Organizer
  CREST研究会
- Place of Presentation
  宮城県　仙台市　東北大学
- Year and Date
  2014-12-24
- Data Source
  KAKENHI-PROJECT-25460352
[Presentation] B細胞最終分化過程におけるPrdm1遺伝子のエピゲノム制御の解明2013
- Author(s)
  武藤哲彦
- Organizer
  若手ワークショップ@鬼怒川
- Place of Presentation
  鬼怒川
- Year and Date
  2013-01-24
- Data Source
  KAKENHI-PUBLICLY-23117702
[Presentation] Bach2, HDAC3 and Rif1 repress Blimp-1 gene expression in B cells through the deacetylation of histone H3 K92013
- Author(s)
  田中　拡、武藤哲彦、落合恭子、ブリドン　アンドレイ、加藤恭丈、仁尾正記、五十嵐和彦
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  兵庫県、神戸市
- Data Source
  KAKENHI-PROJECT-25460352
[Presentation] B細胞最終分化過程におけるPrdm1遺伝子のエピゲノム制御の解明2013
- Author(s)
  武藤哲彦、田中拡、落合恭子、ブリドンアンドレイ、加藤恭丈、仁尾正記、星川裕、野田哲生、五十嵐和彦
- Organizer
  若手ワークショップ@鬼怒川
- Place of Presentation
  鬼怒川
- Data Source
  KAKENHI-PROJECT-23790322
[Presentation] The repression of plasma cell differentiation by Bach2 allows activated B cells to execute class switch recombination2011
- Author(s)
  A.Muto
- Organizer
  ESF-JSPS Frontier Science Conference Series for Young Researchers Cutting Edge Immunology and its Clinical Application
- Place of Presentation
  Hulshort, The Netherlands
- Year and Date
  2011-03-01
- Data Source
  KAKENHI-PROJECT-21790261
[Presentation] The repression of plasma cell differentiation by Bach2 allows activated B cells to execute class switch recombination2011
- Author(s)
  A.Muto
- Organizer
  Tohoku University Global COE for conquest of Signal Transduction Diseases with "Network Medicine" Internal Minisymposium
- Place of Presentation
  仙台
- Year and Date
  2011-02-04
- Data Source
  KAKENHI-PROJECT-21790261
[Presentation] Structure and dynamics of the B cell gene regulatory network that balances antibody class switch and plasma cell differentiation2010
- Author(s)
  武藤哲彦
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21790261
[Presentation] Structure and dynamics of the B cell gene regulatory network that balances antibody class switch and plasma cell differentiation2010
- Author(s)
  A.Muto, K.Ochiai, Y.Kimura, K.Calame, D.Ikebe, S.Tashiro, K.Igarashi
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  神戸
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-21790261
[Presentation] Structure and dynamics of the B cell gene regulatory network that balances antibody class switch and plasma cell differentiation2010
- Author(s)
  武藤哲彦
- Organizer
  14th International Congress of Immunology
- Place of Presentation
  神戸
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PUBLICLY-21117503
[Presentation] Bach2 is required for B-1 B cell development2009
- Author(s)
  武藤哲彦
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PUBLICLY-21117503
[Presentation] Bach2 is required for B-1 cell development2009
- Author(s)
  武藤哲彦, 五十嵐和彦
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21790261
[Presentation] Bach2 is required for B-1 B cell development2009
- Author(s)
  武藤哲彦
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21790261
[Presentation] Bach2は形質細胞分化を抑制し活性化B細胞にクラススイッチを実行させる2008
- Author(s)
  武藤哲彦
- Organizer
  分子生物学会・日本生化学会合同年会(BMB)
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19790202
[Presentation] Bach2による形質細胞分化過程の転写ネットワークの調節2008
- Author(s)
  武藤哲彦
- Organizer
  '08遺伝情報DECODE・冬のワークショップ(転写研究会共催)
- Place of Presentation
  湯沢
- Year and Date
  2008-01-21
- Data Source
  KAKENHI-PROJECT-19790202
[Presentation] Bach2による形質細胞分化過程の転写ネットワークの調節2008
- Author(s)
  武藤哲彦
- Organizer
  '08遺伝情報DECODE・冬のワークショップ(転写研究会共催)
- Place of Presentation
  新潟県湯沢
- Year and Date
  2008-01-21
- Data Source
  KAKENHI-PROJECT-18012006
[Presentation] Bach2は形質細胞分化の抑制し活性化B細胞にクラススイッチを実行させる2008
- Author(s)
  武藤哲彦
- Organizer
  分子生物学会・日本生化学会合同年会
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19790202
[Presentation] Bach2による形質細胞分化過程の転写ネットワークの調節2008
- Author(s)
  武藤哲彦
- Organizer
  '08遺伝情報DECODE・冬のワークショップ(転写研究会共催)
- Place of Presentation
  新潟県湯沢
- Year and Date
  2008-01-21
- Data Source
  KAKENHI-PROJECT-19790202
[Presentation] Bach2が支配するB細胞免疫応答遺伝子ネットワークの役割2007
- Author(s)
  武藤哲彦
- Organizer
  分子生物学会・日本生化学学会合同年会(BMB)
- Place of Presentation
  横浜
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19790202
[]

1. IGARASHI Kazuhiko (00250738)

# of Collaborated Projects: 5 results

# of Collaborated Products: 13 results
2. TASHIRO Satoshi (20243610)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. MURAYAMA Kazutaka (40400452)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. MOTOHASHI Hozumi (00282351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. KATOH Yasutake (40397914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MATSUI Miki (00455784)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. IKURA Tsuyoshi (70335686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 太田力 (10290892)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. MINAMIYAMA Yukiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. ICHIKAWA Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. MATSUMOTO Mitsuyo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. SATO masaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 伊藤友子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 内藤裕二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 高木智久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 齋藤正男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 高田尚良

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 藤原亨

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
19. 黒崎知博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 中山啓子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 舟山亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 菅井学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 高橋克

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 清水章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 張替秀郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Muto Akihiko 武藤 哲彦

MUTO Akihiko 武藤 哲彦

Research Projects

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Co-Researchers

B細胞免疫応答における鉄代謝制御と機能の解明Principal Investigator

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Elucidation of diverse response mechanisms of activated B cells by single cell analysisPrincipal Investigator

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Analysis of Bach2 expression level-dependent regulation of B cell immune responsePrincipal Investigator

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Analysis of regulatory process of plasma cell differentiation by gene regulatory networksPrincipal Investigator

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Regulation of Bach2 intrinsically disordered region by ligand

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活性酸素シグナルによる液性免疫制御因子Ｂａｃｈ２の活性調節機構の解明Principal Investigator

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Elucidation of physiological role of the Bach2 ubiquitinationPrincipal Investigator

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転写因子Bach2をハブとする活性酸素シグナル-遺伝子ネットワーク共役機構の解明Principal Investigator

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Regulation of immune cell responses by heme

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Analysis of regulatory mechanism of early B cell development by Bach transcriptional factorsPrincipal Investigator

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Functional analysis of Bach2 target genes.Principal Investigator

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転写因子Bach2によるB細胞増殖調節機構の解析Principal Investigator

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転写因子Bach2によるB細胞増殖関連遺伝子の調節機構の解明Principal Investigator

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Project Period (FY)

Muto Akihiko 武藤哲彦

MUTO Akihiko 武藤哲彦