TAKABATAKE Noriaki 高畠典明

Researcher Number	80344795
Affiliation (based on the past Project Information) *help	2007 – 2008: Yamagata University, School of Medicine, Lecturer 2003 – 2006: 山形大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine Except Principal Investigator Respiratory organ internal medicine
Keywords	Principal Investigator COPD / IPF / Endothelial Injury / 慢性閉塞性肺疾患 / 肺毛細血管内皮細胞機能障害 / 突発性肺線維症 / 123 I-MIBG肺シンチグラム / 喫煙 / SNP / PLA2 … More / 体重減少 / 肺毛細血管内皮機能障害 / 洗い出し率 / Iodine-123-Metaiodobenzylguanidine / 肺毛細血管内皮細胞の障害 / ^<123>I-MIBGシンチグラム … More Except Principal Investigator MafB / metastasis / lung adenocarcinoma / integrin / invasion / clarithromycin / lung cancer / thymidine phosphorylase / pulmonary emphysema / cigarette smoking / transcription factor / alveolar macrophage / 肺気腫 / 喫煙 / 転写因子 / 肺胞マクロファージ / 肺胞マクロフィージ / clearthromycin / clarithromycin (CAM) / invasiveness / thymidine phosphorylase (TP) / Clarithromycin / Thymidine phosphorylase Less

Research for the mechanism of the body weight loss in patients with chronic obstructive pulmonary diseasePrincipal Investigator
- Principal Investigator
  
  TAKABATAKE Noriaki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Yamagata University
Assessment for the mechanisms of anti-apoptotic effects of transcription factor MafB in alveolar macrophages of emphysematous lungs induced by cigarette smoke exposure
- Principal Investigator
  
  SHIBATA Yoko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Yamagata University
The significance of endothelial cell dysfunction in pulmonary microvessels in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosisPrincipal Investigator
- Principal Investigator
  
  TAKABATAKE Noriaki
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Yamagata University
Role of thymidine phosphorylase on invasive potential in lung adenocarcinoma
- Principal Investigator
  
  SATA Makoto
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  National Cardiovascular Center Research Institute
  Yamagata University
Role of transcription factor MafB in alveolar macrophages of smoking-induced emphysema
- Principal Investigator
  
  SHIBATA Yoko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Yamagata University
慢性閉塞性肺疾患の新たな発症機序の解明:肺毛細血管内皮細胞機能障害の関与Principal Investigator
- Principal Investigator
  
  高畠典明
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Yamagata University
Roles of thymidine phosphorylase on invasiveness and metastasis in lung cancer
- Principal Investigator
  
  SATA Makoto
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Yamagata University

All 2008 2007 2006 2005 2003 Other

All Journal Article Presentation

[Journal Article] A nonfunctioning single nucleotide polymorphism in olfactory receptor gene fanily is associated with the forced expiratory volume in the first second/the forced vital capacity values of pulmonary function test in a Japanese population2007
- Author(s)
  Takabatake, N, et. al.
- Journal Title
  
  Biochem Biophys Res Commun 364.3
  
  Pages: 662-667
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590835
[Journal Article] Anonfunctioning single nucleotide polymorphism in olfactory receptor gene family is associated with the forced expiratory volume in the first second/the forced vital capacity values of pulmonary function test in a Japanese population2007
- Author(s)
  Takabatake N, et. al.
- Journal Title
  
  Biochem Biophys Res Commun 364.3
  
  Pages: 662-667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590835
[Journal Article] A nonfunctioning single nucleotide polymorphism in olfactory receptor gene family isassociated with the forced expiratory volume in the first second/the forced vital capacity values of pulmonary function test in a Japanese population2007
- Author(s)
  Takabatake N, et. al.
- Journal Title
  
  Biochem Biophys Res Commun 364.3
  
  Pages: 662-667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590880
[Journal Article] A nonfunctioning single nucleotide polymorphism in olfactory receptor gene family is associated with the forced expiratory volume in the first second/the forced vital capacity values of pulmonary function test in a Japanese population2007
- Author(s)
  Takabatake N., et. al.
- Journal Title
  
  Biochem Biophys Res Commun 364
  
  Pages: 662-667
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590835
[Journal Article] Enhanced expression of MafB inhibits macrophage apoptosis induced by cigarette smoke exposure.2007
- Author(s)
  Machiya J, Shibata Y, Yamauchi K, Hirama N, Wada T, Inoue S, Abe S, Takabatake N, Sata M, Kubota I
- Journal Title
  
  Am J Respir Cell Mol Biol 36
  
  Pages: 418-426
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590779
[Journal Article] Increased surfactant protein-D and foamy alveolar macrophages in smoking-induced mouse emphysema.2007
- Author(s)
  Hirama N, Shibata Y, Otake K, Machiya J, Wada T, Inoue S, Abe S, Takabatake N, Sata M, Kubota I
- Journal Title
  
  Respirology 12
  
  Pages: 191-201
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590779
[Journal Article] Intronic single-nucleotide polymorphisms in Bcl-2 are associated with chronic obstructive pulmonary disease severity.2007
- Author(s)
  Sata M, Takabatake N, Inoue S, Shibata Y, Abe S, Machiya J, Wada T, Ji G, Kido T, Matsuura T, Muramatsu M, Kubota I
- Journal Title
  
  Respirology 12
  
  Pages: 34-41
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590779
[Journal Article] Clarithromycin suppresses invasiveness of human lung adenocarcinoma cells.2007
- Author(s)
  Wada T, Sata M, Sato J, Tokairin Y, Machiya J, Hirama N, Arao T, Inoue S, Takabatake N, Shibata Y, Kubota I
- Journal Title
  
  Chemotherapy 53
  
  Pages: 77-84
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590779
[Journal Article] A single polymorphism in CCL1 gene predicts acute exacerbations in COPD.2006
- Author(s)
  Takabatake N, Shibata Y, Abe S, Wada T, Machiya J, Igarashi A, Tokairin Y, Ji G, Sato H, Sata M, Takeishi Y, Emi M, Muramatsu M, Kubota I
- Journal Title
  
  Am J Respir Crit Care Med 174
  
  Pages: 875-885
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590779
[Journal Article] A single nucleotide polymorphism in the CCL1 gene predicts acute exacerbations in chronic obstructive pulmonary disease.2006
- Author(s)
  Takabatake N. et al.
- Journal Title
  
  Am J Respir Crit Care Med. 174
  
  Pages: 875-885
- Data Source
  KAKENHI-PROJECT-17590778
[Journal Article] A single nucleotide polymorphism in the CCL1 gene predicts acute exacerbations in chronic obstructive pulmonary disease.2006
- Author(s)
  Takabatake N. et al.
- Journal Title
  
  Am J Respir Crit Care Med 174
  
  Pages: 875-885
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590778
[Journal Article] A single nucleotide polymorphism in the CCL1 gene predicts acute exacerbations in chronic obstructive pulmonary disease2006
- Author(s)
  Takabatake N. et al.
- Journal Title
  
  Am J Respir Crit Care Med. 174
  
  Pages: 875-885
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590778
[Journal Article] A single polymorphism in CCL1 gene predicts acute exacerbations in COPD2006
- Author(s)
  Takabatake N, et al.
- Journal Title
  
  Am J Respir Crit Care Med 174
  
  Pages: 875-885
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590779
[Journal Article] Impaired Systemic Cell-Mediated Immunity and Increased Susceptibility to Acute Respiratory Tract Infections in Patients with COPD2005
- Author(s)
  Takabatake N, Sata M, et al.
- Journal Title
  
  Respir Med 99
  
  Pages: 485-492
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590796
[Journal Article] A Novel Polymorphism in Secretory Phospholipase A_2 IID is Associated with Body Weight Loss in COPD.2005
- Author(s)
  Takabatake N, Sata M, et al.
- Journal Title
  
  Am J Respir Crit Care Med 172
  
  Pages: 1097-1104
- Data Source
  KAKENHI-PROJECT-17590779
[Journal Article] Impaired systemic cell-mediated immunity and increased susceptibility to acute respiratory tract infections in patients with COPD.2005
- Author(s)
  Takabatake N, Sata M, Abe S, Inoue S, Saito H, Yuki H, Shibata Y, Kubota I
- Journal Title
  
  Resp Med 99
  
  Pages: 485-492
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590796
[Journal Article] Involvement of pulmonary endothelial cell injury in the pathogenesis of pulmonary fibrosis : clinical assessment by ^<123>I-MIBG lung scintigraphy.2005
- Author(s)
  Takabatake N, Arao T, Sata M, Abe S, Inoue S, Shibata Y, Takeishi Y, Kubota I
- Journal Title
  
  Eur J Nucl Med Imaging 32
  
  Pages: 221-228
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590796
[Journal Article] Circulating levels of soluble Fas ligand in cachexic patients with COPD are higher than those in non-cachexic patients with COPD.2005
- Author(s)
  Takabatake N, Arao T, Sata M, Inoue S, Abe S, Shibata Y, Kubota I
- Journal Title
  
  Intern Med 44
  
  Pages: 1137-1143
- NAID
  10016885943
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590779
[Journal Article] Impaired systemic cell-mediated immunity and increased susceptibility to acute respiratorv tract infections in patients with COPD.2005
- Author(s)
  Takabatake N.et al.
- Journal Title
  
  Respir Med 99
  
  Pages: 485-492
- Data Source
  KAKENHI-PROJECT-17590778
[Journal Article] A novel polymorphism in secretory phospholipase A_2-IID is : associated with body weight loss in COPD.2005
- Author(s)
  Takabatake N, Sata M, Inoue S, Shibata Y, Abe S, Wada T, Machiya J, Ji G, Matsuura T, Takeishi Y, Muramatsu M, Kubota I
- Journal Title
  
  Am J Respir Crit Care Med 172 (Originally published in press as DOI:10.1164/rccm.200503-3190C on July 7 2005)
  
  Pages: 1097-1104
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590779
[Journal Article] Circulating levels of soluble Fas ligand in cachexic patients with COPD are higher than those in non-cachexic patients with COPD2005
- Author(s)
  Takabatake N.et al.
- Journal Title
  
  Intern Med. 44
  
  Pages: 1137-1143
- NAID
  10016885943
- Data Source
  KAKENHI-PROJECT-17590778
[Journal Article] Involvement of pulmonary endothelial cell injury in the pathogenesis of pulmonary fibrosis : clinical assessment by 123I-MIBG lung scintigraphy2005
- Author(s)
  Takabatake N, Arao T, Sata M, et al.
- Journal Title
  
  European Journal of Nuclear Medicine and Molecular Imaging 32
  
  Pages: 221-228
- Data Source
  KAKENHI-PROJECT-15790407
[Journal Article] Involvement of pulmonary endothelial cell injury in the pathogenesis of pulmonary fibrosis : clinical assessment by ^<123>I-MIBG lung scintigraphy.2005
- Author(s)
  Takabatake N, Arao T, Sata M, Abe S, Inoue S, Shibata Y, Honma T, Takahashi K, Okada A, Takeishi Y, Kubota I
- Journal Title
  
  Eur J Nucl Med Mol Imaging 32
  
  Pages: 221-228
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590779
[Journal Article] Involvement of pulmonary endothelial cell injury in the pathogenesis of pulmonary fibrosis : clinical assessment by ^<123>I-MIBG lung scintigraphy2005
- Author(s)
  Takabatake N, Arao T, Sata M, et al.
- Journal Title
  
  Eur J Nucl Med Mol Imaging 32
  
  Pages: 221-228
- Data Source
  KAKENHI-PROJECT-15590796
[Journal Article] Impaired systemic cell-mediated immunity and increased susceptibility to acute respiratory tract infections in patients with COPD.2005
- Author(s)
  Takabatake N, Sata M, Abe S, Inoue S, Saito H, Yuki H, Shibata Y, Kubota I
- Journal Title
  
  Respir Med 99
  
  Pages: 485-492
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590779
[Journal Article] In vivo evidence of endothelial injury in chronic obstructive pulmonary disease by lung scintigraphic assessment of (123)I-metaiodobenzylguanidine.2003
- Author(s)
  Arao T, Takabatake N, Sata M, et al.
- Journal Title
  
  Journal of Nuclear Medicine 44
  
  Pages: 1747-1754
- Data Source
  KAKENHI-PROJECT-15790407
[Journal Article] Role of thymidine phosphorylase on invasiveness and metastasis in lung adenocarcinoma.2003
- Author(s)
  Sato J, Sata M, Nakamura H, Inoue S, Wada T, Takabatake N, Otake K, Tomoike H, Kubota I
- Journal Title
  
  Int J Cancer 106
  
  Pages: 863-870
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590796
[Journal Article] In vivo evidence of endothelial injury in chronic obstructive pulmonary disease by lung scintigraphic assessment of ^<123>I-metaiodobenzylguanidine2003
- Author(s)
  Arao T, Takabatake N, Sata M, et al.
- Journal Title
  
  J Nucl Med 44
  
  Pages: 1747-1754
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590796
[Journal Article] In vivo evidence of endothelial injury in chronic obstructive pulmonary disease by lung scintigraphic assessment of ^<123>I-metaiodobenzylguanidine.2003
- Author(s)
  Arao T, Takabatake N, Sata M, Abe S, Shibata Y, Honma T, Takahashi K, Okada A, Takeishi Y, Kubota I
- Journal Title
  
  J Nucl Med 44
  
  Pages: 1747-1754
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590796
[Journal Article] Gly80Ser Polymorphism of Phospholipase A2-IID Is Associated with Cytokine Inducibility in A549 Cells
- Author(s)
  Igarashi A, Shibata Y, Yamauchi K, Osaka D, Takabatake N et.al.
- Journal Title
  
  2009 Respiration (In Press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590880
[Journal Article] Altered expression of antimicrobial molecules in cigarette smoke-exposed emphysematous mice lungs
- Author(s)
  Shibata Y, Abe S, Inoue S, Takabatake N et.al.
- Journal Title
  
  2008 Respirology 13
  
  Pages: 1061-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590880
[Presentation] 肺細胞における分泌型ホスホリパーゼA2-IIDの第80番目のアミノ酸多型とサイトカイン誘導能との関係2008
- Author(s)
  五十嵐朗、柴田陽光、高畠典明ら
- Organizer
  第48回日本呼吸器学会学術講演会
- Place of Presentation
  神戸
- Year and Date
  2008-06-15
- Data Source
  KAKENHI-PROJECT-19590880
[Presentation] A Novel Polytnorphisrn in Secretory Phosphetipase A 2-llD ls Associated with Body Weight Loss in Chronic Obstructive Pulmonary Disease2007
- Author(s)
  Takabatake, N., et. al.
- Organizer
  ATS 2007 San Francisco
- Place of Presentation
  San Francisco, USA
- Year and Date
  2007-05-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590835
[Presentation] A Novel Polymorphism in Secretory Phospholipase A 2-llD Is Associated with Body Weight Loss in Chronic Obstructive Pulmonary Disease2007
- Author(s)
  Takabatake N., et. al.
- Organizer
  ATS 2007 San Francisco
- Place of Presentation
  San Francisco, USA
- Year and Date
  2007-05-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590835
[Presentation] A Single Nucleotide Polymorphism in CCL1 Gene Predicts Acute Exacerbaions in Chronic Obstructive Pulmonary Disease2007
- Author(s)
  Takabatake, N., et. al.
- Organizer
  ATS 2007 San Francisco
- Place of Presentation
  San Francisco, USA
- Year and Date
  2007-05-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590835
[Presentation] A novel polymorphism in secretory phospholipase A2-IID is associated with body weight loss in chronic obstructive pulmonary disease2007
- Author(s)
  Takabatake N., et. al.
- Organizer
  ATS 2007 San Francisco
- Place of Presentation
  San Francisco, USA
- Year and Date
  2007-05-22
- Data Source
  KAKENHI-PROJECT-19590880
[Presentation] A Single Nucleotide Polymorphism in CCL1 Gene Predicts Acute Exacerbations in Chronic Obstructive Pulmonary Disease2007
- Author(s)
  Takabatake N., et. al.
- Organizer
  ATS 2007 San Francisco
- Place of Presentation
  San Francisco, USA
- Year and Date
  2007-05-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590835

1. SHIBATA Yoko (60333978)

# of Collaborated Projects: 5 results

# of Collaborated Products: 12 results
2. SATA Makoto (00280892)

# of Collaborated Projects: 4 results

# of Collaborated Products: 17 results
3. NITOBE Joji (30400542)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TAKASAKI Satoshi (20400541)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MIYAMOTO Takuya (20447204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TAKEISHI Yasuchika (40272067)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ABE Shuichi (40400543)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. IGARASHI Akira

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. KIMURA Tomomi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. OSAKA Daisuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

TAKABATAKE Noriaki 高畠 典明

Research Projects

Research Products

Co-Researchers

Research for the mechanism of the body weight loss in patients with chronic obstructive pulmonary diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Assessment for the mechanisms of anti-apoptotic effects of transcription factor MafB in alveolar macrophages of emphysematous lungs induced by cigarette smoke exposure

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The significance of endothelial cell dysfunction in pulmonary microvessels in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of thymidine phosphorylase on invasive potential in lung adenocarcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of transcription factor MafB in alveolar macrophages of smoking-induced emphysema

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

慢性閉塞性肺疾患の新たな発症機序の解明:肺毛細血管内皮細胞機能障害の関与Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of thymidine phosphorylase on invasiveness and metastasis in lung cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] A nonfunctioning single nucleotide polymorphism in olfactory receptor gene fanily is associated with the forced expiratory volume in the first second/the forced vital capacity values of pulmonary function test in a Japanese population2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Anonfunctioning single nucleotide polymorphism in olfactory receptor gene family is associated with the forced expiratory volume in the first second/the forced vital capacity values of pulmonary function test in a Japanese population2007

Author(s)

Journal Title

Data Source

[Journal Article] A nonfunctioning single nucleotide polymorphism in olfactory receptor gene family isassociated with the forced expiratory volume in the first second/the forced vital capacity values of pulmonary function test in a Japanese population2007

Author(s)

Journal Title

Data Source

[Journal Article] A nonfunctioning single nucleotide polymorphism in olfactory receptor gene family is associated with the forced expiratory volume in the first second/the forced vital capacity values of pulmonary function test in a Japanese population2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Enhanced expression of MafB inhibits macrophage apoptosis induced by cigarette smoke exposure.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Increased surfactant protein-D and foamy alveolar macrophages in smoking-induced mouse emphysema.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Intronic single-nucleotide polymorphisms in Bcl-2 are associated with chronic obstructive pulmonary disease severity.2007

Author(s)

Journal Title

Description

Data Source

[Journal Article] Clarithromycin suppresses invasiveness of human lung adenocarcinoma cells.2007

TAKABATAKE Noriaki 高畠典明