Shimomura Hirofumi 下村裕史

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SHIMOMURA Hirofumi 下村裕史

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Researcher Number	80348002
Other IDs
Affiliation (Current)	2025: 北里大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2014 – 2015: 自治医科大学, 医学部, 准教授 2013: 自治医科大学, 医学部, 講師 2010 – 2011: 自治医科大学, 医学部, 講師 2009: 自治医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Bacteriology (including mycology) Except Principal Investigator Bacteriology (including Mycology)
Keywords	Principal Investigator 新規ピロリ菌感染症治療薬 / 抗菌活性 / 合成プロゲステロン / 抗腫瘍作用 / 抗菌作用 / ホスファチジルエタノールアミン / プロゲステロン誘導体 / 狭域スペクトル抗癌剤 / 極狭域スペクトル抗菌薬 / グリセロリン脂質 … More / 飽和脂肪酸 / 不飽和脂肪酸 / ステロイド / ピロリ菌 … More Except Principal Investigator 消化器 / 細菌 / ディフィシル菌 / ダブルバルーン内視鏡 / ニトロソ化合物 / ナイセリア / ピロリ菌 / 消化管 / 胃 / 小腸 / 細菌叢 / 生理 / 構造 Less

Development of new steroidal bactericidal substances for Helicobacter pyloriPrincipal Investigator
- Principal Investigator
  
  Shimomura Hirofumi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Jichi Medical University
A quantitative analysis of bacterial flora in the small intestine
- Principal Investigator
  
  HIRAI Yoshikazu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Jichi Medical University

All 2015 2014 2012 2011 2010 2009

All Journal Article Presentation

[Journal Article] Phosphatidylethanolamine, but not phosphatidylglycerol‐cardiolipin, isolated from two species of Helicobacter binds cholesterol over cholesteryl ester2015
- Author(s)
  Avarzed Amgalanbaatar, Kouichi Hosoda, Hirofumi Shimomura
- Journal Title
  
  Lipids
  
  Volume: 50 Issue: 8 Pages: 799-804
- DOI
  10.1007/s11745-015-4043-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460544
[Journal Article] Antibacterial activity of a novel synthetic progesterone species carrying a linoleic acid molecule against Helicobacter pylori and the hormonal effect of its steroid on a murine macrophage-like cell line2014
- Author(s)
  Amgalanbaatar A, Shimomura H, Hosoda K, Hayashi S, Yokota K, Hirai Y
- Journal Title
  
  J Steroid Biochem Mol Biol
  
  Volume: 140 Pages: 17-25
- DOI
  10.1016/j.jsbmb.2013.10.023
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390428, KAKENHI-PROJECT-25460544
[Journal Article] Phosphatidyl-ethanolamine of Helicobacter pylori functionc as asteroid-binding lipid in the assimilation of free cholesterol and 3β-hydroxl steroids into the bacterial cell membrane2012
- Author(s)
  Shimomura H, Hosoda K, Hayashi S, Yokota K, Hirai Y
- Journal Title
  
  J Bacteriol
  
  Volume: 194 Pages: 2658-2667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590488
[Journal Article] Phosphatidylethanolamine of Helicobacter pylori functions as a steroid-binding lipid in the assimilation of free cholesterol and 3β-hydroxl steroids into the bacterial cell membrane2012
- Author(s)
  Shimomura H, Hosoda K, Hayashi S, Yokota K, Hirai Y
- Journal Title
  
  Journal of Bacteriology
  
  Volume: 194 Issue: 10 Pages: 2658-2667
- DOI
  10.1128/jb.00105-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590488
[Journal Article] Steroid hormones as bactericidal agents to Helicobacter pylori2011
- Author(s)
  Hosoda K, Shimomura H, Hayashi S, Yokota K, Hirai Y
- Journal Title
  
  FEMS Microbiol lett
  
  Volume: 318 Pages: 68-75
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590488
[Journal Article] Helicobacter pyloriと胃癌2011
- Author(s)
  下村裕史、林俊治、平井義一
- Journal Title
  
  臨床と微生物
  
  Volume: 38 Pages: 195-202
- Data Source
  KAKENHI-PROJECT-21590488
[Journal Article] Helicobacte pylori感染と免疫応答2010
- Author(s)
  林俊治、下村裕史、平井義一
- Journal Title
  
  臨床検査
  
  Volume: 54 Pages: 151-157
- Data Source
  KAKENHI-PROJECT-21590488
[Journal Article] Steroid mediate resistance to the bactericidal effect of phosphatidyl-cholines against Helicobacter pylori2009
- Author(s)
  Shimomura H、Hosoda K、Hayashi S(3番目)、Hirai Y(6番目)(全6名)
- Journal Title
  
  FEMS Microbiol Lett
  
  Volume: 301 Pages: 84-94
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590488
[Journal Article] Anabolic utilization of steroid hormones in Helicobacter pylori2009
- Author(s)
  Hosoda K、Shimomura H(2番目)、Hayashi S(3番目)、Hirai Y(6番目)(全6名)
- Journal Title
  
  FEMS Microbiol Lett
  
  Volume: 297 Pages: 173-179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590488
[Presentation] Antibacterial activity of a novel synthetic progesterone species against Helicobacter pylori2014
- Author(s)
  下村裕史、細田浩一、平井義一
- Organizer
  第87回日本細菌学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25460544

1. HIRAI Yoshikazu (00127581)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. YANO Tomonori (30438634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. HAYASHI Shunji (40260765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. HAYASHI Yoshikazu

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. TAKEZAWA Takahito

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HOSODA Kouich

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
7. 横田憲治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shimomura Hirofumi 下村 裕史

SHIMOMURA Hirofumi 下村 裕史

Research Projects

Research Products

Co-Researchers

Development of new steroidal bactericidal substances for Helicobacter pyloriPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A quantitative analysis of bacterial flora in the small intestine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Phosphatidylethanolamine, but not phosphatidylglycerol‐cardiolipin, isolated from two species of Helicobacter binds cholesterol over cholesteryl ester2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antibacterial activity of a novel synthetic progesterone species carrying a linoleic acid molecule against Helicobacter pylori and the hormonal effect of its steroid on a murine macrophage-like cell line2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phosphatidyl-ethanolamine of Helicobacter pylori functionc as asteroid-binding lipid in the assimilation of free cholesterol and 3β-hydroxl steroids into the bacterial cell membrane2012

Author(s)

Journal Title

Data Source

[Journal Article] Phosphatidylethanolamine of Helicobacter pylori functions as a steroid-binding lipid in the assimilation of free cholesterol and 3β-hydroxl steroids into the bacterial cell membrane2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Steroid hormones as bactericidal agents to Helicobacter pylori2011

Author(s)

Journal Title

Data Source

[Journal Article] Helicobacter pyloriと胃癌2011

Author(s)

Journal Title

Data Source

[Journal Article] Helicobacte pylori感染と免疫応答2010

Author(s)

Journal Title

Data Source

[Journal Article] Steroid mediate resistance to the bactericidal effect of phosphatidyl-cholines against Helicobacter pylori2009

Author(s)

Journal Title

Data Source

[Journal Article] Anabolic utilization of steroid hormones in Helicobacter pylori2009

Author(s)

Journal Title

Data Source

[Presentation] Antibacterial activity of a novel synthetic progesterone species against Helicobacter pylori2014

Author(s)

Organizer

Place of Presentation

Data Source

Shimomura Hirofumi 下村裕史

SHIMOMURA Hirofumi 下村裕史