Hirasawa Manabu 平沢学

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HIRASAWA Manabu 平沢学

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Researcher Number	80365345
Other IDs
Affiliation (based on the past Project Information) *help	2018 – 2020: 慶應義塾大学, 医学部(信濃町), 訪問講師 2015: 慶應義塾大学, 医学部, 研究員 2011 – 2015: 慶應義塾大学, 医学部, 共同研究員 2012: 慶應義塾大学, 医学部, 研究員 2008 – 2009: Keio University, 医学部, 助教
Review Section/Research Field	Principal Investigator Ophthalmology / Basic Section 56060:Ophthalmology-related
Keywords	Principal Investigator 加齢黄斑変性 / アンギオポイエチン様タンパク / 酸化ストレス / AMP活性化プロテインキナーゼ / 網膜光障害 / 代謝 / 老化 / 網膜 / 炎症性サイトカイン / アンギオポイエチン様蛋白 … More / マクロファージ / 脈絡膜新生血管 / アンギオポイエチン様タンパク加齢黄斑変性 / 転写因子 / 網膜色素上皮 / 上皮間葉移行 Less

Analysis of the role of AMPK in the retina for the development of a novel treatment for atrophic age-related macular degenerationPrincipal Investigator
- Principal Investigator
  
  Hirasawa Manabu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Keio University
Investigation of ANGPTL2 involvement in pathogenesis of age-related macular degeneration.Principal Investigator
- Principal Investigator
  
  HIRASAWA MANABU
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University
Involvement of Angptl2 in pathogenesis of Age-relatedmacular degenerationPrincipal Investigator
- Principal Investigator
  
  HIRASAWA Manabu
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University
Epithelial-Mesenchymal Transition of Retinal Pigment Epithelium in Age-related Macular Degeneration in SOD1 dificient mice.Principal Investigator
- Principal Investigator
  
  HIRASAWA Manabu
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Keio University

All 2016 2015 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book

[Book] メディカルレビュー社、患者さんから浴びせられる眼科疾患100の質問2008
- Author(s)
  平沢学, 他
- Publisher
  メディカルビュー社
- Data Source
  KAKENHI-PROJECT-20791269
[Book] 他、加齢黄斑変性の患者さんへの指導必須3項目2008
- Author(s)
  平沢学, 他
- Publisher
  眼科ケアメディカルビュー社
- Data Source
  KAKENHI-PROJECT-20791269
[Journal Article] Angiopoietin-like protein 2 is a multistep regulator of inflammatory neovascularization in a murine model of age-related macular degeneration.2016
- Author(s)
  M. Hirasawa, K. Takubo, H. Osada, S. Miyake, E. Toda, M. Endo, K. Umezawa, K. Tsubota, Y. Oike and Y. Ozawa
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 291 Issue: 14 Pages: 7373-7385
- DOI
  10.1074/jbc.m115.710186
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350975, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-25462734, KAKENHI-PUBLICLY-15H01520, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-15K10903, KAKENHI-PROJECT-26670405
[Journal Article] 着色非球面多焦点乱視矯正眼内レンズ（SND1T3，SND1T4，SND1T5，SND1T6）の白内障摘出眼を対象とした臨床試験成績2015
- Author(s)
  中村　邦彦，ビッセン宮島弘子，林　　　研，吉野　真未，平沢　　学，桝本　美樹，瀧本　峰洋，堀川　久美，前田　直之
- Journal Title
  
  日本眼科学会雑誌
  
  Volume: 119 Pages: 7-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462734
[Journal Article] Cyclooxygenase inhibitor improved an exudative lesion of choroidal neovascular- ization in age-related macular degene- ration2011
- Author(s)
  Misa Suzuki, Takayoshi Suzuki, Aoi Nagano, Manabu Hirasawa, Kenichi Sakuyama, Nobuhisa Mizuki.
- Journal Title
  
  European journal of ophthalmology
  
  Volume: 22 Pages: 495-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792003
[Journal Article] Neuroprotective response after photo dynamic therapy: role of vascular endo- thelial growth factor.2011
- Author(s)
  Misa Suzuki, Yoko Ozawa, Shunsuke Kubota, Manabu Hirasawa, Seiji Miyake, Kousuke Noda, Kazuo Tsubota, Kazuaki Kadonosono, Susumu Ishida.
- Journal Title
  
  Journal of Neuroinflammation
  
  Volume: 8 Pages: 176-176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23792003
[Journal Article] フェムトセカンドレーザーによる角膜減張切開術の初期成績2011
- Author(s)
  吉野真未、ビッセン宮島弘子、平沢学
- Journal Title
  
  眼科手術
  
  Volume: 25 Pages: 176-176
- Data Source
  KAKENHI-PROJECT-23792003
[Journal Article] Secondary macular hole associated with central retinal vein occulusion treated with corticosteroid injection.2009
- Author(s)
  Hirasawa M, et al
- Journal Title
  
  Japanese Journal of Ophthalmology 53
  
  Pages: 279-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791269
[Journal Article] Secondary macular hole associated with central retinal vein occulusion treated with corticosteroid injection2009
- Author(s)
  Hirasawa M, Noda K, Shinoda H, Ozawa Y, Tsubota K, Ishida S.
- Journal Title
  
  Japanese Journal of Ophthalmology 53
  
  Pages: 279-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791269
[Journal Article] Retinal dysfunction and progressive retinal cell death in SOD1-deficient mice2008
- Author(s)
  Hashizume K Hirasawa M, et.al.
- Journal Title
  
  American Journal of Pathology 172
  
  Pages: 1325-1331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791269
[Journal Article] Retinal dysfunction and progressive retinal cell death in SOD1-deficient mice2008
- Author(s)
  Hashizume K, Hirasawa M, Imamura Y, Noda S, Shimizu T, Kurihara T, Noda K, Shinoda K, Ozawa Y, Ishida S, Miyake Y, Shirasawa T, Tsubota K.
- Journal Title
  
  Am J Pathol 172
  
  Pages: 1325-1331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791269
[Journal Article] アンチエイジングサプリメント処方2008
- Author(s)
  平沢学
- Journal Title
  
  アンチエイジング医学の基礎と臨床改訂2版
  
  Pages: 268-269
- Data Source
  KAKENHI-PROJECT-20791269
[Journal Article] 加齢黄斑変性動物モデル2008
- Author(s)
  平沢学、今村裕
- Journal Title
  
  網膜硝子体診療updateIV 第62巻増刊号
  
  Pages: 208-210
- Data Source
  KAKENHI-PROJECT-20791269
[Journal Article] 加齢黄斑変性の予防と生活習慣2008
- Author(s)
  平沢学、今村裕
- Journal Title
  
  眼科領域におけるアンチエイジング医学 50
  
  Pages: 409-419
- Data Source
  KAKENHI-PROJECT-20791269
[Presentation] Angiopoietin-like protein 2 の加齢黄斑変性における役割2016
- Author(s)
  平沢学, 田久保圭誉,　長田秀斗,　三宅誠司,　戸田枝里子,　遠藤元誉,　梅沢一夫,　坪田一男,　尾池雄一,　小沢洋子
- Organizer
  第16回日本抗加齢医学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-06-10
- Data Source
  KAKENHI-PROJECT-25462734
[Presentation] 脈絡膜新生血管モデルにおけるAngiopoietin-like 2の関与2013
- Author(s)
  平沢　学
- Organizer
  第117回日本眼科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23792003
[Presentation] Involvement of Angiopoietin-like protein 2 in Laser-induced Choroidal Neovascularization2013
- Author(s)
  Manabu Hirasawa
- Organizer
  Association for Research in Vision and Ophthalmology
- Place of Presentation
  Seatle, USA
- Data Source
  KAKENHI-PROJECT-25462734
[Presentation] 脈絡膜新生血管モデルにおけるAngiopoietin-like 2の関与2013
- Author(s)
  平沢学
- Organizer
  第117回日本眼科学会総会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Data Source
  KAKENHI-PROJECT-25462734
[Presentation] Laser in situ keratomileusis後眼における多焦点眼内レンズ挿入の臨床成績2012
- Author(s)
  平沢学,ビッセン宮島弘子,吉野真未,野中亮子,大木伸一, 南慶一郎
- Organizer
  第66回日本臨床眼科学会
- Place of Presentation
  京都
- Year and Date
  2012-10-28
- Data Source
  KAKENHI-PROJECT-23792003
[Presentation] 多焦点レンズ挿入後に単焦点眼内レンズに交換した3例2012
- Author(s)
  大木伸一,ビッセン宮島弘子,平沢学,吉野真未
- Organizer
  第27回日本白内障屈折矯正手術学会
- Place of Presentation
  東京
- Year and Date
  2012-06-17
- Data Source
  KAKENHI-PROJECT-23792003
[Presentation] Histological Changes After Photodynamic Therapy (PDT) Combined With Anti-vascular Endothelial Growth Factor (VEGF) Therapy In The Mouse Retina2012
- Author(s)
  Suzuki M, Kubota S, Hirasawa M, Miyake S, Noda K, Tsubota K, Kadonosono K, Ishida S, Ozawa Y.
- Organizer
  ARVO Annual Meeting Fort Lauderdale FL
- Place of Presentation
  USA
- Year and Date
  2012-05-09
- Data Source
  KAKENHI-PROJECT-23792003
[Presentation] フェムトセカンドレーザーによる角膜減張切開術の初期成績2012
- Author(s)
  吉野真未, ビッセン宮島弘子, 平沢学, 大木伸一, 佐藤久美子, 南慶一郎.
- Organizer
  第35回日本眼科手術学会総会
- Place of Presentation
  名古屋
- Year and Date
  2012-01-29
- Data Source
  KAKENHI-PROJECT-23792003
[Presentation] 当院における多焦点眼内レンズ挿入希望例の検討2012
- Author(s)
  佐藤久美子,ビッセン宮島弘子,吉野真未,平沢学,大木伸一,大熊泉
- Organizer
  第27回日本白内障屈折矯正手術学会
- Place of Presentation
  東京
- Year and Date
  2012-06-17
- Data Source
  KAKENHI-PROJECT-23792003
[Presentation] 小沢洋子光線力学的療法に伴う血管内皮増殖因子の発現亢進の生物学的意義2012
- Author(s)
  鈴木美砂,久保田俊介,平沢学,三宅誠司,野田航介,門之園一明,石田晋
- Organizer
  第116回日本眼科学会総会
- Place of Presentation
  東京
- Year and Date
  2012-04-08
- Data Source
  KAKENHI-PROJECT-23792003
[Presentation] Association of Angiopoietin-like Protein 2 with Inflammatory Signals in the Human Retinal Pigment Epithelium2012
- Author(s)
  Hirasawa M, Endo M, Miyake S, Narimatsu T, Kubota S, Suzuki M, Ishida S, Tsubota K, Oike Y, Ozawa Y
- Organizer
  ARVO Annual Meeting Fort Lauderdale FL
- Place of Presentation
  USA
- Year and Date
  2012-05-09
- Data Source
  KAKENHI-PROJECT-23792003
[Presentation] Association of Angiopoietin-like Protein 2 with Inflammatory Signals in the Human Retinal Pigment Epithelium2012
- Author(s)
  平沢　学
- Organizer
  ARVO Annual Meeting
- Place of Presentation
  Fort Lauderdale
- Data Source
  KAKENHI-PROJECT-23792003
[Presentation] The Protective Effect of AICAR on the Neural Retina during Inflammation in mice2012
- Author(s)
  Kamoshita M, Yuki K, Kubota S, Hirasawa M, Narimatsu T, Nagai N, Tsubota K, Ozawa Y.
- Organizer
  ARVO Annual Meeting Fort Lauderdale FL
- Place of Presentation
  USA
- Year and Date
  2012-05-09
- Data Source
  KAKENHI-PROJECT-23792003
[Presentation] SOD1ノックアウトマウスにおける網膜神経節細胞数の減少2011
- Author(s)
  結城賢哉、小沢洋子、吉田哲、栗原俊英、平沢学、野田航介、石田晋、坪田一男
- Organizer
  第115回日本眼科学会総会
- Place of Presentation
  東京
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-23792003
[Presentation] 斜乱視例への回折型多焦点眼内レンズ挿入2011
- Author(s)
  平沢学,ビッセン宮島弘子,野中亮子,大木伸一,南慶一郎
- Organizer
  第65回日本臨床眼科学会
- Place of Presentation
  東京
- Year and Date
  2011-10-10
- Data Source
  KAKENHI-PROJECT-23792003
[Presentation] Role of Vascular Endothelial Growth Factor Induced by Photodynamic Therapy2011
- Author(s)
  Suzuki M, Ozawa Y, Kubota S, Hirasawa M, Miyake S, Narimatsu T, Tsubota K, Kadonosono K, Noda K, Ishida S.
- Organizer
  ARVO Annual Meeting Fort Lauderdale FL
- Place of Presentation
  USA
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-23792003
[Presentation] Cytokine Regulation of Transcriptional Factor Snail in Human Retinal Pigment Epithelium2011
- Author(s)
  Hirasawa M, Noda K, Suzuki M, Ozawa Y, Tsubota K, Ishida S.
- Organizer
  ARVO Annual Meeting Fort Lauderdale FL
- Place of Presentation
  USA
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-23792003
[Presentation] Translocation of Beta-catenin In The Retinal Pigment Epithelium After Light-exposure2011
- Author(s)
  Narimatsu T, Kubota S, Miyake S, Hirasawa M, Kurihara T, Ishida S, Ozawa Y, Tsubota K.
- Organizer
  ARVO Annual Meeting Fort Lauderdale FL
- Place of Presentation
  USA
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-23792003
[Presentation] 東京歯科大学水道橋病院眼科における周術期の安全対策2010
- Author(s)
  斎野泰代,平沢学,ビッセン宮島弘子,熊谷知子,大木伸一,吉野真未
- Organizer
  第27回日本眼科看護研究会
- Place of Presentation
  宮崎
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-23792003
[Presentation] 白内障手術症例におけるα1遮断薬の使用状況2009
- Author(s)
  西別府弘子, 五十嵐俊, 間宮純子, 苗村かおり, 平沢学, 宮田博, 高尾良洋
- Organizer
  第19回日本医療薬学会年会
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20791269
[Presentation] 緑内障手術後における脈絡膜剥離の統計2009
- Author(s)
  宮田博、平沢学
- Organizer
  日本緑内障学会
- Place of Presentation
  沖縄コンベンションセンター
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-20791269
[Presentation] 緑内障手術後の遷延性脈絡膜剥離2009
- Author(s)
  宮田博、平沢学
- Organizer
  日本緑内障学会
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-20791269
[Presentation] Oxidative Stress Markers in Japanese Patients With Age-Related Macular Degeneration: A Pilot Study2008
- Author(s)
  Hashizume K, ImamuraY, Hirasawa M, Sawanobori M, Ishida S, Kurosaka D, Tsubota K.
- Organizer
  ARVO 2008
- Data Source
  KAKENHI-PROJECT-20791269
[Presentation] Age-related changes of gene expression profile in retina of SOD1-deficient mice2008
- Author(s)
  Hirasawa M, Imamura Y, Hashizume K, Noda K, Ishida S, Tsukamoto N, Kudo-Saitoh C, Kawakami Y, Tsubota K.
- Organizer
  ARVO 2008
- Data Source
  KAKENHI-PROJECT-20791269
[Presentation] マウス脈絡膜新生血管モデルにおけるAngiopoietin-like protein 2　の役割
- Author(s)
  小沢洋子　平沢学　田久保圭誉　三宅誠司　梅沢一夫　尾池雄一　坪田一男
- Organizer
  第14回日本抗加齢学会総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-06-06 – 2014-06-08
- Data Source
  KAKENHI-PROJECT-25462734
[Presentation] The clinical outcomes of apodized diffractive +3.0 D multifocal toric IOL
- Author(s)
  K. Nakamura, H. BissenMiyajima K. Hayashi M. Hirasawa M. Matsumoto M. Takimoto N. Maeda
- Organizer
  European Society of Cataract & Refractive Surgeons Annual Meeting
- Place of Presentation
  Excel London,London,イギリス
- Year and Date
  2014-09-12 – 2014-09-17
- Data Source
  KAKENHI-PROJECT-25462734
[Presentation] Comparison between toric and non-toric intraocular lens implantation in eyes with corneal astigmatisms
- Author(s)
  M. Hirasawa,H. BissenMiyajima Y. Inoue T. Nishimura H. Takehara K. Nishikawa
- Organizer
  European Society of Cataract & Refractive Surgeons Annual Meeting
- Place of Presentation
  Excel London,London,イギリス
- Year and Date
  2014-09-12 – 2014-09-17
- Data Source
  KAKENHI-PROJECT-25462734
[Presentation] フェムトセカンドレーザー白内障手術の基礎と臨床
- Author(s)
  平沢学
- Organizer
  第29回　JSCRS学術総会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-07-11 – 2014-07-13
- Invited
- Data Source
  KAKENHI-PROJECT-25462734
[Presentation] Long-term rotational stability of micro-incision hydrophobic acrylic aspheric toric intraocular lens in a Japanese multicenter study
- Author(s)
  H. Bissen-Miyajima, K. Negishi O. Hieda M. Hirasawa H. Torii K. Yamamura S. Kinoshita
- Organizer
  European Society of Cataract & Refractive Surgeons Annual Meeting
- Place of Presentation
  Excel London,London,イギリス
- Year and Date
  2014-09-12 – 2014-09-17
- Data Source
  KAKENHI-PROJECT-25462734
[Presentation] Postoperative Measurement of the Diameter of Femtosecond Laser-created Anterior Capsulotomy by Using the Implanted Intraocular Lens as a Reference Point
- Author(s)
  M. Hirasawa, K. Minami, R. Yumiyama, S. Ooki, H. Bissen-Miyajima
- Organizer
  Asia-ARVO 2015
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2015-02-16 – 2015-02-19
- Data Source
  KAKENHI-PROJECT-25462734
[Presentation] 白内障眼に対するトーリック眼内レンズ挿入効果の多施設後ろ向き研究
- Author(s)
  平沢学、ビッセン宮島弘子、大木伸一、井上康、竹原弘泰、西村知久、西川久美子
- Organizer
  第29回　JSCRS学術総会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-07-11 – 2014-07-13
- Data Source
  KAKENHI-PROJECT-25462734
[Presentation] 着色非球面+2.5D近方加入多焦点眼内レンズSN6AD2(SV25TO)の臨床試験成績
- Author(s)
  平沢　学、ビッセン宮島弘子、林　研、吉野真未、中村邦彦、吉田起章、桝本美樹、佐々木博司
- Organizer
  第68回日本臨床眼科学会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2014-11-13 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-25462734
[Presentation] 多焦点トーリック眼内レンズの初期臨床成績
- Author(s)
  平沢　学、ビッセン宮島弘子、大木伸一、中村邦彦
- Organizer
  第38回　日本眼科手術学会
- Place of Presentation
  京都国際会議場
- Year and Date
  2015-01-30 – 2015-02-01
- Data Source
  KAKENHI-PROJECT-25462734

1. OZAWA YOKO (90265885)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. 梅沢一夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hirasawa Manabu 平沢 学

HIRASAWA Manabu 平沢 学

Research Projects

Research Products

Co-Researchers

Analysis of the role of AMPK in the retina for the development of a novel treatment for atrophic age-related macular degenerationPrincipal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Investigation of ANGPTL2 involvement in pathogenesis of age-related macular degeneration.Principal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Involvement of Angptl2 in pathogenesis of Age-relatedmacular degenerationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

Epithelial-Mesenchymal Transition of Retinal Pigment Epithelium in Age-related Macular Degeneration in SOD1 dificient mice.Principal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

[Book] メディカルレビュー社、患者さんから浴びせられる眼科疾患100の質問2008

Author(s)

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Hirasawa Manabu 平沢学

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