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ONIZUKA MAKOTO  鬼塚 真仁

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ONIZUKA Makoto  鬼塚 真仁

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Researcher Number 80366012
Other IDs
Affiliation (Current) 2025: 東海大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2024: 東海大学, 医学部, 教授
2023: 東海大学, 医学部, 准教授
2017 – 2020: 東海大学, 医学部, 准教授
2012 – 2014: 東海大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
Basic Section 54010:Hematology and medical oncology-related / Basic Section 49030:Experimental pathology-related / Hematology
Except Principal Investigator
Basic Section 38050:Food sciences-related / Hematology / Social dentistry
Keywords
Principal Investigator
造血幹細胞移植 / 骨髄環境 / 老化マーカー / 同種造血幹細胞移植 / Horvath clock / メチル化年齢解析 / mev1 / 造血ホメオスタシス / 造血幹細胞 / 活性酸素 … More / myeloid-skewing / ROS過剰産生 / Sdhc変異マウス / PAI-1 / 脂肪細胞 / 全エクソン解析 / ROS / ミトコンドリア複合体II / complex II / ミトコンドリア / 全エクソンシークエンス / Sdhc-mut マウス / 酸化ストレス / 骨髄異形成症候群 / 造血幹細胞移植学 / 移植片対宿主病 / 非感染性移植後肺合併症 / マウス肺合併症モデル / レニン・アンジオテンシン系 / 移植後肺合併症 … More
Except Principal Investigator
低襲撃的治療 / チロシンキナーゼ阻害薬(TKI) / Pterostilbene / BCR/ABL / 慢性骨髄性白血病(CML) / 移植後再発 / HLA片側アリル欠損 / HLA / HLA遺伝子 / SS-SBT法 / 次世代シーケンシング / マイクロサテライト解析 / 同種造血幹細胞移植 / LOH / HLA不一致移植 / 同種移植後再発 / 次世代シークエンサー / HLA-LOH / 乳がん / 造血幹細胞移植 / 造血器腫瘍 / 乳癌 / 味覚受容体 / 薬物療法 / 化学療法 / 味覚障害 Less
  • Research Projects

    (6 results)
  • Research Products

    (4 results)
  • Co-Researchers

    (15 People)
  •  Development of a novel minimally invasive treatment for refractory and therapy-resistant hematological malignancies using food extracts.

    • Principal Investigator
      川田 浩志
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 38050:Food sciences-related
    • Research Institution
      Tokai University
  •  The Phenomenon of Stem Cell Aging according to Methylation Estimates of Age After Hematopoietic Stem Cell TransplantationPrincipal Investigator

    • Principal Investigator
      鬼塚 真仁
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Tokai University
  •  An analysis for development of myelodysplastic syndrome and influence of ROSPrincipal Investigator

    • Principal Investigator
      ONIZUKA Makoto
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Tokai University
  •  Elucidation of the taste disorders using gene expression analysis

    • Principal Investigator
      DENDA Yuya
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Social dentistry
    • Research Institution
      Tokai University
  •  An analysis of HLA-LOH in relapsed tumor by using NGS after allogeneic stem cell transplantation

    • Principal Investigator
      AOYAMA Yasuyuki
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Hematology
    • Research Institution
      Tokai University
  •  Renin-angiotensin system and non-infectious pulmonary complication after stem cell transplantationPrincipal Investigator

    • Principal Investigator
      ONIZUKA MAKOTO
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Tokai University

All 2021 2020 2014

All Journal Article Presentation

  • [Journal Article] Plasminogen activator inhibitor type-1 is a negative regulator of hematopoietic regeneration in the adipocyte-rich bone marrow microenvironment2021

    • Author(s)
      Harada Kaito、Yahata Takashi、Onizuka Makoto、Ibrahim Abd Aziz、Kikkawa Eri、Miyata Toshio、Ando Kiyoshi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 557 Pages: 180-186

    • DOI

      10.1016/j.bbrc.2021.04.017

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K14702, KAKENHI-PROJECT-18K07073, KAKENHI-PROJECT-20K22941, KAKENHI-PROJECT-23K21386
  • [Journal Article] ACE deletion polymorphism is associated with a high risk of non-infectious pulmonary complications after stem cell transplantation.2014

    • Author(s)
      Mitsuki Miyamoto, Makoto Onizuka, Shinichiro Machida, Masako Toyosaki, Jun Amaki, Yasuyuki Aoyama, Hidetsugu Kawai, Ai Sato, Naoki Hayama, Yoshiaki Ogawa, Hiroshi Kawada, Kiyoshi Ando
    • Journal Title

      International Jornal of Hematology

      Volume: 99 Issue: 2 Pages: 175-175

    • DOI

      10.1007/s12185-013-1494-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591431
  • [Presentation] Mitochondrial complex II dysfunction leads to hematopoietic stem cells aging and myelodysplastic syndrome2020

    • Author(s)
      Kaito Harada*, Takashi Yahata, Makoto Onizuka, Takamasa Ishii, Abd Aziz Ibrahim, Eri Kikkawa, Yoichi Gondo,Kiyoshi Ando
    • Organizer
      日本血液学会
    • Data Source
      KAKENHI-PROJECT-18K07073
  • [Presentation] MITOCHONDRIAL ELECTRON TRANSPORT CHAIN COMPLEX II DYSFUNCTION DRIVES PREMATURE AGING OF HEMATOPOIETIC STEM CELLS2020

    • Author(s)
      Kaito Harada*, Takashi Yahata, Makoto Onizuka, Takamasa Ishii, Abd Aziz Ibrahim, Eri Kikkawa, Yoichi Gondo, Kiyoshi Ando
    • Organizer
      第25回欧州血液学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07073
  • 1.  DENDA Yuya (70734424)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  AOYAMA Yasuyuki (50648475)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  SHINA Takashi (00317744)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  太田 嘉英 (60233152)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  徳田 裕 (20163975)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  笹野 高嗣 (10125560)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  庄司 憲明 (70250800)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  佐藤 しづ子 (60225274)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  八幡 崇 (10398753)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 10.  石井 恭正 (20548680)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 11.  川田 浩志 (20276801)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  鈴木 利貴央 (70514371)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  KIKKAWA Eri
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SUZUKI shingo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  IBRAHIM Abd Aziz
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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