TAKAHARA Akira 高原章

… Alternative Names

高原章タカハラアキラ

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Researcher Number	80377481
Other IDs	https://orcid.org/0000-0003-2190-2444
Affiliation (Current)	2025: 東邦大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 東邦大学, 薬学部, 教授 2011 – 2017: 東邦大学, 薬学部, 教授 2012: 東邦大学, 薬学部, 准教授 2007 – 2010: Toho University, 薬学部, 准教授
Review Section/Research Field	Principal Investigator Applied pharmacology / Basic Section 55050:Anesthesiology-related Except Principal Investigator General pharmacology / Cardiovascular medicine
Keywords	Principal Investigator 心房細動 / アルドステロン / 慢性容量負荷 / 心房拡大 / 薬物治療戦略 / 揮発性麻酔薬 / 完全房室ブロック / 徐脈 / 早期後脱分極 / QT延長 … More / セボフルラン / プロポフォール / IKr遮断薬 / Torsade de Pointes / 催不整脈作用 / 麻酔薬 / 動静脈瘻 / TRPC3チャネル / イオンチャネル / 有効不応期 / 伝達遅延 / ナトリウムチャネル / 心筋袖 / 肺動脈 / 抗不整脈薬 / カルバコール / 活動電位 / 撃発活動 / 異常自動能 / 肺静脈 / アップストリーム治療 / 心筋再分極異常 / N型Ca^<2+>チャネル / 薬物治療 / 心臓突然死 / QT延長症候群 … More Except Principal Investigator イメージング / 自動能 / 肺静脈心筋 / Ca^<2+>交換機構 / Na^+ / 腎デナベーション / 交感神経 / 高血圧 / カルシウム / 心房細動 / カルシウムイメージング / 薬理学 / T型カルシウムチャネル / 筋小胞体 / Ca^<2+>チャネル / Na^+/Ca^<2+>交換機構 / 肺動脈心筋 / 細胞内カルシウム / ナトリウムカルシウム交換機構 / ミトコンドリア / ナトリウム・カルシウム交換機構 / 虚血再灌流障害 / 心筋 Less

Electrophysiological analysis of proarrhythmic properties of volatile anesthetics using an originally developed arrhythmogenic modelPrincipal Investigator
- Principal Investigator
  
  高原章
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Toho University
ANALYSIS OF THERAPEUTIC TARGET MOLECULES FOR SUSTAINED ATRIAL FIBRILLATION CAUSED BY CHRONIC VOLUME OVERLOADPrincipal Investigator
- Principal Investigator
  
  TAKAHARA Akira
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Toho University
RENAL DENERVATION: NOVEL THERAPY FOR RESISTANT HYPERTENSION
- Principal Investigator
  
  Sato Akira
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  University of Tsukuba
ANALYSIS OF THERAPEUTIC TARGET MOLECULES FOR ARRHYTHMIAS IN THE NEWLY DEVELOPED ANIMAL MODEL OF SUSTAINED ATRIAL FIBRILLATIONPrincipal Investigator
- Principal Investigator
  
  TAKAHARA Akira
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Toho University
Spatio-temporal analysis of intracellularcalcium oscillation in the pulmonary vein myocardium
- Principal Investigator
  
  NAMEKATA Iyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Toho University
The role of intracellular calcium and sodium-calcium exchanger in the automaticity of pulmonary vein myocardium.
- Principal Investigator
  
  TANAKA Hikaru
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Toho University
INVESTIGATION OF THERAPEUTIC TARGET MOLECULES FOR ATRIAL FIBRILLATION REGULATING ELECTRICAL EXCITATION IN PULMONARY VEINPrincipal Investigator
- Principal Investigator
  
  TAKAHARA Akira
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Toho University
Fluorescence imaging analysis of Na^+/Ca^<2+> exchanger dynamics in myocardial ischemia reperfusion injury
- Principal Investigator
 
 NAMEKATA Iyuki
- Project Period (FY)
 2008 – 2009
- Research Category
 
 Grant-in-Aid for Young Scientists (Start-up)
- Research Field
 
 General pharmacology
- Research Institution
 Toho University
PHARMACOTHERAPEUTIC STRATEGY FOR PREVENTION OF CARDIAC SUDDEN DEATH CAUSED BY VENTRICULAR REPOLARIZATION ABNORMALITYPrincipal Investigator
- Principal Investigator
  
  TAKAHARA Akira
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Toho University

[Book] Antihypertensive Drugs2012
- Author(s)
  Akira Takahara
- Total Pages
  16
- Publisher
  InTech-Open Access Publisher
- Data Source
  KAKENHI-PROJECT-21590602
[Journal Article] Evaluating the relationship between ocular blood flow and systemic organ blood flow in hemorrhagic shock using a rabbit model2024
- Author(s)
  Kento Watanabe, Tomoaki Shiba, Akira Takahara, Hiroshi Homma, Tetsuya Komatsu, Yusuke Tanino, Yoshinobu Nagasawa, Megumi Aimoto, Yuichi Hori
- Journal Title
  
  Scientific Reports
  
  Volume: 14 Issue: 1 Pages: 3749-3749
- DOI
  10.1038/s41598-024-54467-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09032, KAKENHI-PROJECT-23K11836
[Journal Article] The role of arterial stiffness in the onset of Takotsubo cardiomyopathy observed with noradrenaline administration and intracranial blood injection in rabbits2023
- Author(s)
  Takahashi Mao、Miyazaki Chikao、Xin Cao、Sato Shuji、Shimizu Kazuhiro、Chiba Tatsuo、Tsukuma Hisayuki、Komatsu Tetsuya、Aimoto Megumi、Nagasawa Yoshinobu、Takahara Akira、Shirai Kohji
- Journal Title
  
  Heart and Vessels
  
  Volume: 38 Issue: 5 Pages: 740-748
- DOI
  10.1007/s00380-022-02223-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09032
[Journal Article] Differential Effects of Ca2+ Channel Blockers Nifedipine and Cilnidipine on Arterial Elasticity in the Aortic and Femoral Arterial Segments of Anesthetized Rabbits2023
- Author(s)
 Akira Sato, Yoshinobu Nagasawa, Honami Suzuki, Kiyoshi Sakuma, Tatsuo Chiba, Megumi Aimoto, Akira Takahara
- Journal Title
 
 Biological and Pharmaceutical Bulletin
 
 Volume: 46 Issue: 9 Pages: 1324-1331
- DOI
 10.1248/bpb.b23-00391
- ISSN
 0918-6158, 1347-5215
- Year and Date
 2023-09-01
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-22K09032, KAKENHI-PROJECT-23K07564, KAKENHI-PROJECT-23K11836
[Journal Article] The Antiarrhythmic Action of the Na+/Ca2+ Exchanger Inhibitor SEA0400 on Drug-Induced Long QT Syndrome Depends on the Severity of Proarrhythmic Conditions in Anesthetized Atrioventricular Block Rabbits2023
- Author(s)
 Satoshi Kawakami, Kazuhiro Takada, Megumi Aimoto, Yoshinobu Nagasawa, Taichi Kusakabe , Keisuke Kato , Akira Takahara
- Journal Title
 
 Biological and Pharmaceutical Bulletin
 
 Volume: 46 Issue: 8 Pages: 1120-1127
- DOI
 10.1248/bpb.b23-00202
- ISSN
 0918-6158, 1347-5215
- Year and Date
 2023-08-01
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-22K09032, KAKENHI-PROJECT-23K06034, KAKENHI-PROJECT-23K07564
[Journal Article] Role of Rho Kinase in Regulating Arterial Stiffness in Anesthetized Rabbits2023
- Author(s)
  Akira Takahara, Manami Matsumoto, Akira Sato, Shuto Inose, Megumi Aimoto, Yoshinobu Nagasawa
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 46 Issue: 12 Pages: 1846-1850
- DOI
  10.1248/bpb.b23-00591
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2023-12-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09032, KAKENHI-PROJECT-23K07564, KAKENHI-PROJECT-23K11836
[Journal Article] Cardiac Electropharmacological Effects of Antidiarrheal Drug Loperamide and Its Antidote Naloxone in Anesthetized Guinea Pigs2022
- Author(s)
  Takahara Akira、Izawa Sayaka、Seki Shota、Aimoto Megumi、Nagasawa Yoshinobu
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 45 Issue: 4 Pages: 542-546
- DOI
  10.1248/bpb.b22-00024
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2022-04-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09032
[Journal Article] Role of cardiac α1-adrenoreceptors for the torsadogenic action of IKr blocker nifekalant in the anesthetized atrioventricular block rabbit2022
- Author(s)
  Kawakami Satoshi、Kambayashi Ryuichi、Takada Kazuhiro、Aimoto Megumi、Nagasawa Yoshinobu、Takahara Akira
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 150 Issue: 2 Pages: 67-73
- DOI
  10.1016/j.jphs.2022.07.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09032
[Journal Article] Chronic Volume Overload Caused by Abdominal Aorto-Venocaval Shunt Provides Arrhythmogenic Substrates in the Rat Atrium2022
- Author(s)
  Aimoto Megumi、Yagi Keita、Ezawa Aya、Tsuneoka Yayoi、Kumada Kohei、Hasegawa Takeshi、Kuze Tetsuo、Chiba Toshiki、Nagasawa Yoshinobu、Tanaka Hikaru、Takahara Akira
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 45 Issue: 5 Pages: 635-642
- DOI
  10.1248/bpb.b22-00031
- ISSN
  0918-6158, 1347-5215
- URL
  https://localhost/en/publications/b7f00e78-0747-4198-a283-f378c1440733
- Year and Date
  2022-05-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22924, KAKENHI-PROJECT-22K09032
[Journal Article] Influence of chronic volume overload-induced atrial remodeling on electrophysiological responses to cholinergic receptor stimulation in the isolated rat atria2018
- Author(s)
  Cao Xin、Aimoto Megumi、Fukumoto Marie、Nagasawa Yoshinobu、Tanaka Hikaru、Takahara Akira
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 136 Issue: 2 Pages: 73-78
- DOI
  10.1016/j.jphs.2017.12.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H07135, KAKENHI-PROJECT-15K08598
[Journal Article] Changes of electrocardiogram and hemodynamics in response to dipyridamole: In vivo comparative analyses using anesthetized beagle dogs and microminipigs2018
- Author(s)
  Ando K, Takahara A, Nakamura Y, Wada T, Chiba K, Goto A, Lubna NJ, Hagiwara-Nagasawa M, Izumi-Nakaseko H, Hoshiai K, Akie Y, Naito AT, Sugiyama A
- Journal Title
  
  Journal of pharmacological sciences
  
  Volume: 136 Issue: 2 Pages: 86-92
- DOI
  10.1016/j.jphs.2018.01.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08559, KAKENHI-PROJECT-15K08598
[Journal Article] The anaesthetized rabbit with acute atrioventricular block provides a new model for detecting drug-induced Torsade de Pointes2017
- Author(s)
  Hagiwara Mihoko、Shibuta Seiji、Takada Kazuhiro、Kambayashi Ryuichi、Nakajo Misako、Aimoto Megumi、Nagasawa Yoshinobu、Takahara Akira
- Journal Title
  
  British Journal of Pharmacology
  
  Volume: 174 Issue: 15 Pages: 2591-2605
- DOI
  10.1111/bph.13870
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08598
[Journal Article] Comparison of anti-anginal effect of cilnidipine with those of nicardipine and nifedipine in the vasopressin-induced angina model of rats.2016
- Author(s)
  Cao X, Nakamura Y, Wada T, Izumi-Nakaseko H, Ando K, Zhu B, Xu B, Takahara A, Saitoh M, Sugiyama A.
- Journal Title
  
  Heart and Vessels
  
  Volume: 31 Issue: 12 Pages: 2045-2052
- DOI
  10.1007/s00380-016-0848-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08598
[Journal Article] Influences of rapid pacing-induced electrical remodeling on pharmacological manipulation of the atrial refractoriness in rabbits.2016
- Author(s)
  Chiba T, Kondo N, Takahara A.
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 130 Issue: 3 Pages: 170-176
- DOI
  10.1016/j.jphs.2016.02.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08598
[Journal Article] In vivo analysis of torsadogenic potential of an antipsychotic drug paliperidone using the acute atrioventricular block rabbit as a proarrhythmia model.2016
- Author(s)
  Hagiwara M, Kambayashi R, Aimoto M, Nagasawa Y, Takahara A.
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 132 Issue: 1 Pages: 48-54
- DOI
  10.1016/j.jphs.2016.05.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08598
[Journal Article] Intravenous anti-influenza drug oseltamivir will not induce torsade de pointes: Evidences from proarrhythmia model and action-potential assay.2016
- Author(s)
  Nakamura Y, Sasaki R, Cao X, Wada T, Hamaguchi S, Izumi-Nakaseko H, Ando K, Tanaka H, Takahara A, Sugiyama A.
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 131 Issue: 1 Pages: 72-75
- DOI
  10.1016/j.jphs.2016.04.018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08598
[Journal Article] Impacts of Surgically-Performed Renal Denervation on the Cardiovascular and Electrophysiological Variables in the Chronic Atrioventricular Block Dogs: Comparison with Those of Amiodarone2016
- Author(s)
  Wada T, Ohara H, Nakamura Y, Yokoyama H, Cao X, Izumi-Nakaseko H, Ando K, Murakoshi N, Sato A, Aonuma K, Takahara A, Nakazato Y, Sugiyama A.
- Journal Title
  
  Circ J
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461042
[Journal Article] Impacts of Surgically Performed Renal Denervation on the Cardiovascular and Electrophysiological Variables in the Chronic Atrioventricular Block Dogs　– Comparison With Those of Amiodarone Treatment –2016
- Author(s)
  Wada T, Ohara H, Nakamura Y, Yokoyama H, Cao X, Izumi-Nakaseko H, Ando K, Murakoshi N, Sato A, Aonuma K, Takahara A, Nakazato Y, Sugiyama A.
- Journal Title
  
  Circ J
  
  Volume: 80 Issue: 7 Pages: 1556-1563
- DOI
  10.1253/circj.CJ-16-0198
- NAID
  130005158909
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08598
[Journal Article] Cardio-ankle vascular index (CAVI) differentiates pharmacological properties of vasodilators nicardipine and nitroglycerin in anesthetized rabbits.2015
- Author(s)
  Chiba T, Yamanaka M, Takagi S, Shimizu K, Takahashi M, Shirai K, Takahara A
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 128 Issue: 4 Pages: 185-192
- DOI
  10.1016/j.jphs.2015.07.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08598
[Journal Article] Comparison of the cardioprotective and renoprotective effects of the L/N-type calcium channel blocker, cilnidipine, in adriamycin-treated spontaneously hypertensive rats.2015
- Author(s)
  Aritomi S, Harada E, Sugino K, Nishimura M, Nakamura T, Takahara A.
- Journal Title
  
  Clinical and Experimental Pharmacology and Physiology
  
  Volume: 42 Issue: 4 Pages: 344-352
- DOI
  10.1111/1440-1681.12360
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08598
[Journal Article] Role of P-Glycoprotein in Regulating Cilnidipine Distribution to Intact and Ischemic Brain2014
- Author(s)
  Yano K, Motegi T, Takimoto S, Hagiwara M, Idota Y, Morimoto K, Takahara A, Ogihara T
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 29 Issue: 3 Pages: 254-258
- DOI
  10.2133/dmpk.DMPK-13-RG-072
- NAID
  130004463376
- ISSN
  1347-4367, 1880-0920
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590669
[Journal Article] L/N型カルシウム拮抗薬シルニジピンの白血球からの活性酸素放出に対する作用2014
- Author(s)
  原田英里, 内田裕久, 杉野多美, 今田智之, 高原章, 山門実
- Journal Title
  
  薬理と治療
  
  Volume: 42 Pages: 413-418
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590669
[Journal Article] Pulmonary Vein Myocardium as a Possible Pharmacological Target for the Treatment of Atrial Fibrillation2014
- Author(s)
  Akira Takahara, Mihoko Hagiwara, Iyuki Namekata, Hikaru Tanaka
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 126 Issue: 1 Pages: 1-7
- DOI
  10.1254/jphs.14R09CP
- NAID
  130004677805
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590334, KAKENHI-PROJECT-24590669, KAKENHI-PROJECT-25860194
[Journal Article] The Conventional Antihistamine Drug Cyproheptadine Lacks QT-interval–Prolonging Action in Halothane-Anesthetized Guinea Pigs: Comparison With Hydroxyzine2014
- Author(s)
  Kobayashi K, Omuro N, Takahara A
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 124 Issue: 1 Pages: 92-98
- DOI
  10.1254/jphs.13159FP
- NAID
  130003382628
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590669
[Journal Article] Electrophysiological Effects of the Antiarrhythmic Drug Bepridil on the Guinea-Pig Pulmonary Vein Myocardium2013
- Author(s)
  Akira Takahara, Kiyoshi Takeda, Mihoko Hagiwara, Hikaru Tanaka
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 36 Issue: 2 Pages: 311-315
- DOI
  10.1248/bpb.b12-00590
- NAID
  130003361367
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590334, KAKENHI-PROJECT-24590669
[Journal Article] Effects of the Fluoroquinolone Antibacterial Drug Ciprofloxacin on Ventricular Repolarization in the Halothane-Anesthetized Guinea Pig2013
- Author(s)
  Matsuo K, Fujiwara K, Omuro N, Kimura I, Kobayashi K, Yoshio T, Takahara A
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 122 Issue: 3 Pages: 205-212
- DOI
  10.1254/jphs.13020FP
- NAID
  10031185414
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590669
[Journal Article] Electrophysiological Effects of an Anti-influenza Drug Oseltamivir on the Guinea-Pig Atrium: Comparison with Those of Pilsicainide2013
- Author(s)
  Takahara A, Suzuki S, Hagiwara M, Nozaki S, Sugiyama A
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 36 Issue: 10 Pages: 1650-1652
- DOI
  10.1248/bpb.b13-00347
- NAID
  130004147313
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590669
[Journal Article] Electrophysiologcal effects of the class I c antiarrhythmic drug pilsicainide on the Guinea-pig pulmonary vein myocardium2012
- Author(s)
  Akira Takahara
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 118 Pages: 506-511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790262
[Journal Article] Electrophysiological effects of the class ic antiarrhythmic drug pilsicainide on the Guinea-pig pulmonary vein myocardium2012
- Author(s)
  Akira Takahara, Kiyoshi Takeda, Yayoi Tsuneoka, Miyoko Hagiwara, Iyuki Namekata, Hikaru Tanaka
- Journal Title
  
  J. Pharmacol Sci
  
  Volume: 118(4) Pages: 506-511
- NAID
  10030572152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590293
[Journal Article] Effects of the Antitussive Drug Cloperastine on Ventricular Repolarization in Halothane-Anesthetized Guinea Pigs2012
- Author(s)
  Akira Takahara
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 120 Issue: 3 Pages: 165-175
- DOI
  10.1254/jphs.12117FP
- NAID
  10031147563
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790262, KAKENHI-PROJECT-24590334, KAKENHI-PROJECT-24590669
[Journal Article] Discovery and evaluation of selective N-type calcium channel blockers: 6-unsubstituted-1,4-dihydropyridine-5-carboxylic acid derivatives.2012
- Author(s)
  Yamamoto T, Niwa S, Tokumasu M, Onishi T, Ohno S, Hagiwara M, Koganei H, Fujita S, Takeda T, Saitou Y, Iwayama S, Takahara A, Iwata S, Shoji M
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 22 Issue: 11 Pages: 3639-3642
- DOI
  10.1016/j.bmcl.2012.04.051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590669
[Journal Article] Electrophysiological Effects of the Class Ic Antiarrhythmic Drug Pilsicainide on the Guinea-Pig Pulmonary Vein Myocardium2012
- Author(s)
  Takahara A, Takeda K, Tsuneoka Y, Hagiwara M, Namekata I, Tanaka H
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 118 Issue: 4 Pages: 506-511
- DOI
  10.1254/jphs.12022FP
- NAID
  10030572152
- ISSN
  1347-8613, 1347-8648
- URL
  https://pure.teikyo.jp/en/publications/893103ef-9b03-4f7e-adb1-31d3721dd5fa
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590602, KAKENHI-PROJECT-22790262, KAKENHI-PROJECT-24590334, KAKENHI-PROJECT-24590669
[Journal Article] Electrophysiological effects of the class I c antiarrhythmic drug pilsicainide on the Guinea-pig pulmonary vein myocardium2012
- Author(s)
  Akira Takahara
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 118 Pages: 506-511
- NAID
  10030572152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590293
[Journal Article] Developmental Changes in Action Potential Prolongation by K+-Channel Blockers in Chick Myocardium2011
- Author(s)
  Nouchi H, Kiryu N, Kimata M, Namekata I, Takahara A, Shigenobu K, Tanaka H
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 115 Issue: 2 Pages: 235-238
- DOI
  10.1254/jphs.10205SC
- NAID
  10029892239
- ISSN
  1347-8613, 1347-8648
- URL
  https://pure.teikyo.jp/en/publications/4e3addda-6482-4d7b-a82d-dfef7d75b02a
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590602
[Journal Article] Electrophysiological and pharmacological characteristics of triggered activity elicited in guinea pig pulmonary vein myocardium.2011
- Author(s)
  高原章
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 115 Pages: 176-181
- NAID
  10029892032
- Data Source
  KAKENHI-PROJECT-21590602
[Journal Article] Asymmetric synthesis and biological evaluations of(+)-and(-)-6-dimethoxymethyl-1, 4-dihydropyridine-3-carboxylic acid derivatives blocking N-type calcium channels2011
- Author(s)
  Yamamoto T, Ohno S, Niwa S, Tokumasu M, Hagiwara M, Koganei H, Fujita S, Takeda T, Saitou Y, Iwayama S, Takahara A, Iwata S, Shoji M.
- Journal Title
  
  Bioorg. Med. Chem. Lett
  
  Volume: 21(11) Issue: 11 Pages: 3317-3319
- DOI
  10.1016/j.bmcl.2011.04.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590602
[Journal Article] Blocking effect of NIP-142 on the KCNQ1/KCNE1 channel current expressed in HEK293 cells2011
- Author(s)
  Iyuki Namekata, Noriko Tsuruoka, Yayoi Tsuneoka, Tomoyuki Matsuda, Akira Takahara, Yoshio Tanaka, Takeshi Suzuki, Tetsuo Takahashi, Naoko Iida-Tanaka and Hikaru Tanaka
- Journal Title
  
  Biol. Pharm. Bull
  
  Volume: 34(1) Pages: 153-155
- NAID
  130000402280
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590293
[Journal Article] Electrophysiological and Pharmacological Characteristics of Triggered Activity Elicited in Guinea-Pig Pulmonary Vein Myocardium2011
- Author(s)
  Takahara A, Sugimoto T, Kitamura T, Takeda K, Tsuneoka Y, Namekata I, Tanaka H
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 115 Issue: 2 Pages: 176-181
- DOI
  10.1254/jphs.10232FP
- NAID
  10029892032
- ISSN
  1347-8613, 1347-8648
- URL
  https://pure.teikyo.jp/en/publications/5b1b90be-7a13-449f-bc48-4d85a5429e8a
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590602, KAKENHI-PROJECT-22790262
[Journal Article] Utility of Short-Term Variability of Repolarization as a Marker for Monitoring a Safe Exercise Training Program in Patients With Cardiac Diseases2011
- Author(s)
  Nishi I, Sugiyama A, Takahara A, Watabe H, Kuroki K, Igawa M, Enomoto T, Iida K, Koseki S, Aonuma K
- Journal Title
  
  Int. Heart J.
  
  Volume: 52 Issue: 5 Pages: 304-307
- DOI
  10.1536/ihj.52.304
- NAID
  130001088314
- ISSN
  1349-2365, 1349-3299
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590602
[Journal Article] Blocking Effect of NIP-142 on the KCNQ1/KCNE1 Channel Current Expressed in HEK293 Cells2011
- Author(s)
  Namekata I, Tsuruoka N, Tsuneoka Y, Matsuda T, Takahara A, Tanaka Y, Suzuki T, Takahashi T, Iida-Tanaka N, Tanaka H
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 34 Issue: 1 Pages: 153-155
- DOI
  10.1248/bpb.34.153
- NAID
  130000402280
- ISSN
  0918-6158, 1347-5215
- URL
  https://pure.teikyo.jp/en/publications/f9586207-0ff1-4e56-a426-70f20d62f992
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590602
[Journal Article] Electrophysiological and pharmacological characteristics of triggered activity elicited in the guinea-pig pulmonary vein myocardium2011
- Author(s)
  Akira Takahara
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 115 Pages: 176-181
- NAID
  10029892032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590293
[Journal Article] Electrophysiological and pharmacological characteristics of triggered activity elicited in the guinea-pig pulmonary vein myocardium2011
- Author(s)
  Akira Takahara
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 115 Pages: 176-181
- NAID
  10029892032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790262
[Journal Article] Developmental changes in action potential prolongation by K^+channel blockers in the chick myocardium2011
- Author(s)
  Hideaki Nouchi, Naoaki Kiryu, Mikio Kimata, Yayoi Tsuneoka, Shogo Hamaguchi, Iyuki Namekata, Akira Takahara, Koki Shigenobu, Hikaru Tanaka
- Journal Title
  
  J. Pharmacol. Sci
  
  Volume: 115(2) Pages: 235-238
- NAID
  10029892239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590293
[Journal Article] Electrophysiological and pharmacological characteristics of triggered activity elicited in the guinea-pig pulmonary vein myocardium2011
- Author(s)
  Akira Takahara, Takahiko Sugimoto, Takuma Kitamura, Kiyoshi Takeda, Yayoi Tsuneoka, Iyuki Namekata, Hikaru Tanaka
- Journal Title
  
  J. Pharmacol Sci
  
  Volume: 115(2) Pages: 176-81
- NAID
  10029892032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590293
[Journal Article] Measurements of Cardiac Ion Channel Subunits in the Chronic Atrioventricular Block Dog2011
- Author(s)
  Takahara A, Wagatsuma H, Aritomi S, Konda T, Akie Y, Nakamura Y, Sugiyama A
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 116 Issue: 1 Pages: 132-135
- DOI
  10.1254/jphs.11019SC
- NAID
  10029894257
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590602
[Journal Article] Effect of NIP-142 on Potassium Channel .ALPHA.-Subunits Kv1.5, Kv4.2 and Kv4.3, and Mouse Atrial Repolarization2010
- Author(s)
  Tanaka H, Namekata I, Hamaguchi S, Kawamura T, Masuda H, Tanaka Y, Iida-Tanaka N, Takahara A
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 33 Issue: 1 Pages: 138-141
- DOI
  10.1248/bpb.33.138
- NAID
  130000140208
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590602
[Journal Article] Intracellular calcium and membrane potential oscillations in the guinea pig and rat pulmonary vein myocardium2010
- Author(s)
  Namekata I, Tsuneoka Y, Akiba A, Nakamura H, Shimada H, Takahara A, Tanaka H
- Journal Title
  
  bioimages
  
  Volume: 18 Pages: 11-22
- NAID
  130004479917
- URL
  https://www.jstage.jst.go.jp/article/bioimages/18/0/18_0_11/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590602
[Journal Article] Intracellular Calcium and Membrane Potential Oscillations in the Guinea Pig and Rat Pulmonary Vein Myocardium2010
- Author(s)
  Iyuki Namekata, Yayoi Tsuneoka, Akiko Akiba, Hideki Nakamura, Hideaki Shimada, Akira Takahara Hikaru Tanaka.
- Journal Title
  
  bioimages
  
  Volume: 18 Issue: 0 Pages: 11-22
- DOI
  10.11169/bioimages.18.11
- NAID
  130004479917
- ISSN
  0919-2719
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790262
[Journal Article] Cardiovascular effects of azelnidipine in comparison with those of amlodipine assessed in the halothane-anesthetized dogs2010
- Author(s)
  Ishizaka T, Takahara A, Iwasaki H, Mitsumori Y, Kise H, Nakamura Y, Sugiyama A
- Journal Title
  
  Basic Clin. Pharmacol. Toxicol
  
  Volume: 106(2) Issue: 2 Pages: 135-143
- DOI
  10.1111/j.1742-7843.2009.00478.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590602
[Journal Article] Effect of NIP-142 on potassium channel alpha-subunits Kv1.5, Kv4.2 and Kv4.3, and mouse atrial repolarization2010
- Author(s)
  Hikaru Tanaka, Iyuki Namekata, Shogo Hamaguchi, Taro Kawamura, Hiroyuki Masuda, Yoshio Tanaka, Naoko Iida-Tanaka, and Akira Takahara
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 33(1) Pages: 138-141
- NAID
  130000140208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590293
[Journal Article] Intracellular calcium and membrane potential oscillations in the guinea-pig and rat pulmonary vein myocardium2010
- Author(s)
  Iyuki Namekata, Yayoi Tsuneoka, Akiko Akiba, Hideki Nakamura, Hideaki Shimada, Akira Takahara and Hikaru Tanaka
- Journal Title
  
  Bioimages
  
  Volume: 18 Pages: 11-22
- NAID
  130004479917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590293
[Journal Article] H_2 receptor-mediated positive inotropic effect of histamine in neonatal guinea-pig left atria2010
- Author(s)
  Naoki Agata, Yoshimitsu Kato, Iyuki Namekata, Akira Takahara, Hikaru Tanaka, Daisuke Chino, Katsuo Koike, Yoshio Tanaka
- Journal Title
  
  Biol. Pharm. Bull
  
  Volume: 33(12) Pages: 2033-2035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590293
[Journal Article] H2 Receptor-Mediated Positive Inotropic Effect of Histamine in Neonatal Guinea-Pig Left Atria2010
- Author(s)
  Agata N, Kato Y, Namekata I, Takahara A, Tanaka H, Chino D, Koike K, Tanaka Y
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 33 Issue: 12 Pages: 2033-2035
- DOI
  10.1248/bpb.33.2033
- NAID
  130000402340
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590602
[Journal Article] Effects of S(+)-efonidipine on the rabbit sinus node action potential and calcium channel subunits CaV1.2, CaV1.3 and CaV 3.12010
- Author(s)
  Hikaru Tanaka, Iyuki Namekata, Toru Ogawa, Yayoi Tsuneoka, Chisa Komikado, Akira Takahara, Naoko Iida-Tanaka, Hiroko Nakaseko, Hiromichi Tsuru, Satomi Adachi-Akahane
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 649(1-3) Pages: 263-267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590293
[Journal Article] Clobutinol delays ventricular repolarization in the guinea pig heart : comparison with cardiac effects of hERG K^+ channel inhibitor E-40312009
- Author(s)
  高原章
- Journal Title
  
  Journal of Cardiovascular Pharmacology 54
  
  Pages: 552-559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590602
[Journal Article] New aspects for the treatment of cardiac diseases based on the diversity of functional controls on cardiac muscles : diversity in the excitation-contraction mechanisms of the heart2009
- Author(s)
  Hikaru Tanaka, Iyuki Namekata, Hideaki Nouchi, Koki Shigenobu, Toru Kawanishi, Akira Takahara
- Journal Title
  
  J. Pharmacol. Sci
  
  Volume: 109(3) Pages: 327-333
- NAID
  10025734834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590293
[Journal Article] Utilities of a halothane-anesthetized, closed-chest, guinea pig as a model to assess the drug-induced QT-interval prolongation2009
- Author(s)
  Sakaguchi Y, Takahara A, Nakamura Y, Akie Y, Sugiyama A
- Journal Title
  
  Basic Clin. Pharmacol. Toxicol 104(1)
  
  Pages: 43-48
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590532
[Journal Article] Involvement of the Na+/Ca2+ exchanger in the automaticity of guinea-pig pulmonary vein myocardium as revealed by SEA0400.2009
- Author(s)
  Iyuki Namekata, Yayoi Tsuneoka, Akira Takahara, Hideaki Shimada, Takahiko Sugimoto, Kiyoshi Takeda, Midori Nagaharu, Koki Shigenobu, Toru Kawanishi, Hikaru Tanaka
- Journal Title
  
  J. Pharmacol. Sci 110(1)
  
  Pages: 111-116
- NAID
  10025736868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890233
[Journal Article] Long-term blockade of L/N-type Ca^<2+> channels by cilnidipine ameliorates repolarization abnormality of the canine hypertrophied heart.2009
- Author(s)
 Takahara A, Nakamura Y, Wagatsuma H, Aritomi S, Nakayama A, Satoh Y, Akie Y, Sugiyama A
- Journal Title
 
 Br. J. Pharmacol (in press)
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-19590532
[Journal Article] 心臓カテーテル検査時に肺動脈解離を起こしたビーグル犬の1例2009
- Author(s)
  安東賢太郎, 中村裕二, 高原章, 杉山篤
- Journal Title
  
  動物の循環器
  
  Volume: 41(2) Pages: 44-48
- NAID
  10025016938
- URL
  https://www.jstage.jst.go.jp/article/jsvc/41/2/41_2_44/_article/-char/ja/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590602
[Journal Article] Clobutinol delays ventricular repolarization in the guinea-pig heart : comparison with cardiac effects of hERG K^+channel inhibitor E-40312009
- Author(s)
  Akira Takahara, Rieko Sasaki, Mariko Nakamura, Akiko Sendo, Yukiko Sakurai, Iyuki Namekata, Hikaru Tanaka
- Journal Title
  
  J. Cardiovasc. Pharmacol
  
  Volume: 54(6) Pages: 552-559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590293
[Journal Article] Famotidine neither affects action potential parameters nor inhibits human ether-a-go-go-related gene (hERG) K+ current2009
- Author(s)
 Nakamura Y, Takahara A, Sugiyama A
- Journal Title
 
 The Journal of Toxicological Sciences
 
 Volume: 34 Issue: 5 Pages: 563-567
- DOI
 10.2131/jts.34.563
- NAID
 110007358571
- ISSN
 0388-1350, 1880-3989
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-21590602
[Journal Article] Long-term blockade of L/N-type Ca^<2+> channels by cilnidipine ameliorates repolarization abnormality of the canine hypertrophied heart2009
- Author(s)
 高原章
- Journal Title
 
 British Journal of Pharmacology 158
 
 Pages: 1366-1374
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-21590602
[Journal Article] Clobutinol delays ventricular repolarization in the guinea-pig heart : comparison with cardiac effects of hERG K^+ channel inhibitor E-40312009
- Author(s)
  Akira Takahara
- Journal Title
  
  Journal of Cardiovascular Pharmacology 54
  
  Pages: 552-559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590293
[Journal Article] Clobutinol delays ventricular repolarization in the guinea pig heart : comparison with cardiac effects of hERG K^+channel inhibitor E-40312009
- Author(s)
  Takahara A, Sasaki R, Nakamura M, Sendo A, Sakurai Y, Namekata I, Tanaka H
- Journal Title
  
  J. Cardiovasc. Pharmacol
  
  Volume: 54(6) Issue: 6 Pages: 552-559
- DOI
  10.1097/fjc.0b013e3181bfb17c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590602
[Journal Article] Clobutinol delays ventricular repolarization in the guinea-pig heart : comparison with cardiac effects of hERG K^+ channel inhibitor E-40312009
- Author(s)
  Akira Takahara
- Journal Title
  
  Journal of Cardiovascular Pharmacology 54
  
  Pages: 552-559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890233
[Journal Article] New aspects for the treatment of cardiac diseases based on the diversity of functional controls on cardiac muscles: diversity in the excitation-contraction mechanisms of the heart.2009
- Author(s)
  Hikaru Tanaka, Iyuki Namekata, Hideaki Nouchi, Koki Shigenobu, Toru Kawanishi, Akira Takahara
- Journal Title
  
  J. Pharmacol. Sci 109(3)
  
  Pages: 327-333
- NAID
  10025734834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890233
[Journal Article] Long-term blockade of L/N-type Ca^<2+> channels by cilnidipine ameliorates repolarization abnormality of the canine hypertrophied heart2009
- Author(s)
 Takahara A, Nakamura Y, Wagatsuma H, Aritomi S, Nakayama A, Satoh Y, Akie Y, Sugiyama A
- Journal Title
 
 Br. J. Pharmacol
 
 Volume: 158(5) Issue: 5 Pages: 1366-1374
- DOI
 10.1111/j.1476-5381.2009.00407.x
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-21590602
[Journal Article] Involvement of the Na^+/Ca^<2+> exchanger in the automaticity of guinea-pig pulmonary vein myocardium as revealed by SEA04002009
- Author(s)
 Iyuki Namekata, Yayoi Tsuneoka, Akira Takahara, Hideaki Shimada, Takahiko Sugimoto, Kiyoshi Takeda, Midori Nagaharu, Koki Shigenobu, Toru Kawanishi, Hikaru Tanaka
- Journal Title
 
 J. Pharmacol. Sci
 
 Volume: 110(1) Pages: 111-116
- NAID
 10025736868
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-21590293
[Journal Article] Species difference in the contribution of T-type calcium current to cardiac pacemaking as revealed by R(-)-efonidipine.2008
- Author(s)
  Hikaru Tanaka, Chisa Komikado, Iyuki Namekata, Hideki Nakamura, Mariko Suzuki, Yayoi Tsuneoka, Koki Shigenobu, Akira Takahara
- Journal Title
  
  J. Pharmacol. Sci 107(1)
  
  Pages: 99-102
- NAID
  10024320633
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890233
[Journal Article] Beat-to-beat variability of repolarization differentiates the extent of torsadogenic potential of multi ion-channel blockers bepridil and amiodarone2008
- Author(s)
  Takahara A, Nakamura Y, Sugiyama A
- Journal Title
  
  Eur. J. Pharmacol 596(1-3)
  
  Pages: 127-131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590532
[Journal Article] Beat-to-beat variability of repolarization differentiates the extent of torsadogenic potential of multi ion-channel blockers bepridil and amiodarone.2008
- Author(s)
  高原章
- Journal Title
  
  European Journal of Pharmacology 596
  
  Pages: 127-131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590532
[Journal Article] Comparison of electropharmacological effects of bepridil and sotalol in the halothane-anesthetized dogs2008
- Author(s)
  Ishizaka T, Takahara A, Iwasaki H, Mitsumori Y, Kise H, Nakamura Y, Sugiyama A.
- Journal Title
  
  Circ. J. 72(6)
  
  Pages: 1003-1011
- NAID
  110006783841
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590532
[Journal Article] Intracellular mechanisms and receptor types for endothelin-1-induced positive and negative inotropy in mouse ventricular myocardium.2008
- Author(s)
  Iyuki Namekata, Shinpei Fujiki, Yuko Kawakami, Rina Moriwaki, Kentaro Takeda, Toru Kawanishi, Akira Takahara, Koki Shigenobu, Hikaru Tanaka
- Journal Title
  
  Naunyn-Schmied. Arch. Pharmacol 376(6)
  
  Pages: 385-395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890233
[Journal Article] Chronic left atrial volume overload abbreviates the action potential duration of the canine pulmonary vein myocardium via activation of IK channel2008
- Author(s)
  Nouchi H, Takahara A, Nakamura H, Namekata I, Sugimoto T, Tsuneoka Y, Takeda K, Tanaka T, Shigenobu K, Sugiyama A, Tanaka H
- Journal Title
  
  Eur. J. Pharmacol 597(1-3)
  
  Pages: 80-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590532
[Journal Article] Intracellular mechanisms and receptor types for endothelin-1-induced positive and negative inotropy in mouse ventricular myocardium2008
- Author(s)
  Namekata I, Fujiki S, Kawakami Y, Moriwaki R, Takeda K, Kawanishi T, Takahara A, Shigenobu K, Tanaka H.
- Journal Title
  
  Naunyn Schmiedebergs Arch Pharmacol 376(6)
  
  Pages: 385-395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590532
[Journal Article] Cardiac effects of L/N-type Ca^<2+> channel blocker cilnidipine in anesthetized dogs.2007
- Author(s)
 Takahara A, Iwasaki H, Nakamura Y, Sugiyama A.
- Journal Title
 
 Eur. J. Pharmacol 565(1-3)
 
 Pages: 166-170
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-19590532
[Journal Article] Cardiovascular profile of the canine torsades de pointes arrhythmia model assessed by echocardiographic and haemodynamic methods2007
- Author(s)
  Takahara A, Sugiyama A, Satoh Y, Iwasaki H, Nakamura Y, Hashimoto K.
- Journal Title
  
  Basic Clin. Pharmacol. Toxicol 101(1)
  
  Pages: 35-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590532
[Journal Article] Cardiac effects of L/N-type Ca^<2+> channel blocker cilnidipine in anesthetized dogs.2007
- Author(s)
 高原章
- Journal Title
 
 European Journal of Pharmacology. 565
 
 Pages: 166-170
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-19590532
[Journal Article] Cardiovascular profile of the canine torsades de pointes arrhythmia model assessed by echocardiographic and haemodynamic methods.2007
- Author(s)
  高原章
- Journal Title
  
  Basic and Clinical Pharmacology and Toxicology 101
  
  Pages: 35-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590532
[Patent] 心房細動を誘発させる方法2011
- Inventor(s)
  杉山篤,高原章,橋本敬太郎
- Industrial Property Rights Holder
  東邦大学
- Industrial Property Number
  2011-015743
- Filing Date
  2011-01-27
- Data Source
  KAKENHI-PROJECT-21590602
[Patent] 心房細動モデル動物の作製方法、心房細動を誘発させる方法及び心房細動を誘発させた動物を用いた心房細動抑制剤の評価方法2011
- Inventor(s)
  杉山篤,高原章,橋本敬太郎
- Industrial Property Rights Holder
  東邦大学
- Acquisition Date
  2011-03-18
- Data Source
  KAKENHI-PROJECT-21590602
[Patent] 持続型心房細動モデル動物、その持続型心房細動誘発方法及び製造方法2011
- Inventor(s)
  高原章
- Industrial Property Rights Holder
  東邦大学
- Industrial Property Number
  2011-144710
- Filing Date
  2011-06-29
- Data Source
  KAKENHI-PROJECT-21590602
[Patent] 催不整脈モデル動物2008
- Inventor(s)
  杉山篤、高原章、佐藤吉沖
- Industrial Property Rights Holder
  株式会社イナリサーチ
- Filing Date
  2008-02-29
- Data Source
  KAKENHI-PROJECT-19590532
[Presentation] 完全房室ブロックウサギモデルによる吸入麻酔薬sevofluraneおよび静脈麻酔薬propofolが有する催不整脈作用特性の分析2023
- Author(s)
  海野和恵, 川上聡士, 相本恵美, 永澤悦伸, 高原章
- Organizer
  第148回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-22K09032
[Presentation] 強心配糖体ジゴキシンがウサギ大動脈および大腿動脈領域の血管弾性に与える影響2023
- Author(s)
  猪瀬柊斗, 永澤悦伸, 佐藤啓, 佐久間清, 千葉達夫, 相本恵美, 高原章
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K09032
[Presentation] 三環系抗うつ薬ノルトリプチリン、アミトリプチリンの過量投与時の心臓電気生理学的作用－イソフルラン麻酔モルモットでの検討－.2023
- Author(s)
  影山夏奈, 永澤悦伸, 相本恵美, 高原章
- Organizer
  第148回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-22K09032
[Presentation] ブレクスピプラゾールがイソフルラン麻酔モルモットの心室再分極過程に与える影響ーアリピプラゾールとの比較ー2023
- Author(s)
  金子萌季, 永澤悦伸, 相本恵美, 高原章
- Organizer
  第148回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-22K09032
[Presentation] In vivo analysis of efficacy of pharmacological intracellular calcium modification on dofetilide-induced torsade de pointes assessed in anesthetized acute atrioventricular block rabbits.2023
- Author(s)
  Yoshinobu Nagasawa, Satoshi Kawakami, Yuki Ishimaru, Megumi Aimoto M, Akira Takahara
- Organizer
  第69回日本不整脈心電学会学術集会
- Data Source
  KAKENHI-PROJECT-22K09032
[Presentation] ノルフロキサシンの心室再分極への影響－イソフルラン麻酔モルモットを用いて－2023
- Author(s)
  津久井楽南, 永澤悦伸, 相本恵美, 高原章
- Organizer
  第148回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-22K09032
[Presentation] Angiotensin IIの急性投与が生体位モルモット心臓での薬物誘発性QT延長に及ぼす影響2023
- Author(s)
  近田里葉, 永澤悦伸, 相本恵美, 高原章
- Organizer
  第148回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-22K09032
[Presentation] ウサギ房室結節焼灼モデルを用いた薬物の抗心房細動作用と催不整脈作用の評価2022
- Author(s)
  高原章, 川上聡士, 相本恵美, 永澤悦伸
- Organizer
  心電学関連春季大会2022
- Data Source
  KAKENHI-PROJECT-22K09032
[Presentation] イバブラジンの徐脈効果が心室再分極時間延長作用に与える影響に関する薬理学的分析2022
- Author(s)
  北野遥, 永澤悦伸, 相本恵美, 高原章
- Organizer
  第146回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-22K09032
[Presentation] 薬物性QT延長症候群に対するL型Ca2+チャネル阻害薬verapamilとNa+/Ca2+交換機構阻害薬SEA0400の抗不整脈作用特性の比較.2022
- Author(s)
  川上聡士, 高田一唐, 石丸雄己, 相本恵美, 永澤悦伸, 高原章
- Organizer
  第32回日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-22K09032
[Presentation] ウサギ催不整脈モデルの適用による吸入麻酔薬isofluraneおよびhalothaneが有する催不整脈・抗不整脈作用特性の分析2022
- Author(s)
  秋葉洋佑, 川上聡士, 相本恵美, 永澤悦伸, 高原章
- Organizer
  第146回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-22K09032
[Presentation] ウサギ房室ブロックモデルにおける致死性不整脈出現パターンの分析2022
- Author(s)
  鹿角隼輔, 川上聡士, 相本恵美, 永澤悦伸, 高原章
- Organizer
  第66回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-22K09032
[Presentation] BaCl2がモルモット生体位心臓および薬物誘発性QT延長に及ぼす影響2022
- Author(s)
  尾関彩衣, 永澤悦伸, 相本恵美, 高原章
- Organizer
  第66回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-22K09032
[Presentation] Sphingosine-1-phosphate Receptor Modulator Fingolimod Suppresses Atrial Fibrillation in Rats with Atrial Enlargement Caused by Chronic Volume Overload.2018
- Author(s)
  相本恵美，永澤悦伸，高原章
- Organizer
  第82回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08598
[Presentation] Influence of Chronic Volume Overload-induced Atrial Remodeling on Electrophysiological Responses to Cholinergic Receptor Stimulation in the Isolated Rat Atria.2018
- Author(s)
  相本恵美，永澤悦伸，高原章
- Organizer
  第82回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08598
[Presentation] Aldosterone慢性負荷で生じる心房細動の持続化におけるNFATの関与 ―動静脈モデルラットを用いた検討―2017
- Author(s)
  小田原一功，相本恵美，永澤悦伸，高原章
- Organizer
  第136回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-15K08598
[Presentation] 急性房室ブロックウサギはアドレナリンα1受容体遮断作用を有するQT延長薬の催不整脈作用を検出できる2017
- Author(s)
  萩原美帆子, 神林隆一, 仲條美佐子, 永澤悦伸, 相本恵美, 高原章
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際会議場（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K08598
[Presentation] 薬物性QT延長症候群に関連する有害事象報告数の抗ヒスタミン薬世代間の違い－薬物の心臓電気薬理学的作用からの検討2017
- Author(s)
  永澤悦伸, 小林加寿子, 相本恵美, 高原章
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際会議場（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K08598
[Presentation] Chronically administered aldosterone can promote stability of atrial fibrillation in the rat model of chronic volume overload2017
- Author(s)
  相本恵美, 永澤悦伸, 高原章
- Organizer
  第81回日本循環器学会学術集会
- Place of Presentation
  ANAクラウンプラザホテル金沢（石川県金沢市）
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-15K08598
[Presentation] 新規心房細動モデルラットの心房細動の持続化におけるaldosteroneの役割2017
- Author(s)
  相本恵美, 永澤悦伸, 高原章
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際会議場（宮城県仙台市）
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-15K08598
[Presentation] The influence of aldosterone on the inducibility of atrial fibrillation in rat abdominal aorto-venocaval shunt model.2016
- Author(s)
  相本恵美, 永澤悦伸, 高原章
- Organizer
  第63回日本不整脈心電学会学術大会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-07-17
- Data Source
  KAKENHI-PROJECT-15K08598
[Presentation] 慢性容量負荷による心房拡大ラットにおける心房細動誘発性の分析2016
- Author(s)
  相本恵美, 八木啓太, 江沢亜耶, 高原章
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15K08598
[Presentation] 抗アレルギー薬の催不整脈リスクに関する検討：in vivoおよびin vitro電気生理学的作用に基づいた統合的評価2016
- Author(s)
  小林加寿子, 相本恵美, 永澤悦伸, 高原章
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15K08598
[Presentation] ウサギ催不整脈モデルにおける抗ヒスタミン薬 hydroxyzine の作用2016
- Author(s)
  仲條美佐子, 萩原美帆子, 永澤悦伸, 相本恵美, 高原章
- Organizer
  第60回日本薬学会関東支部大会
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-15K08598
[Presentation] Aldosterone is a strong biological mediator for induction of AF in rats with pathological condition of chronic volume overload.2016
- Author(s)
  相本恵美, 灘みづき, 高原章
- Organizer
  第80回日本循環器学会学術集会
- Place of Presentation
  仙台国際会議場（宮城県仙台市）
- Year and Date
  2016-03-20
- Data Source
  KAKENHI-PROJECT-15K08598
[Presentation] Effects of vasodilators on the cardio-ankle vascular index (CAVI) in anesthetized rabbits.2016
- Author(s)
  Kiyoshi Sakuma, Tatsuo Chiba, Takenori Morishita, Mari Yamanaka, Megumi Aimoto, Yoshinobu Nagasawa, Koji Shirai, Akira Takahara
- Organizer
  The 26th Meeting of the International Society of Hypertension (Hypertension Seoul 2016)
- Place of Presentation
  ソウル（韓国）
- Year and Date
  2016-09-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08598
[Presentation] Proarrhythmic potential of the rabbit heart under bradycardiac conditions of acute and chronic atrioventricular block.2015
- Author(s)
  萩原美帆子, 相本恵美, 高原章
- Organizer
  第30回日本不整脈学会学術大会／第32回日本心電学会学術集会合同学術大会
- Place of Presentation
  京都国際会議場（京都府京都市）
- Year and Date
  2015-07-29
- Data Source
  KAKENHI-PROJECT-15K08598
[Presentation] 急性房室ブロックウサギにおける薬物誘発性不整脈の発生機序：L型Ca2+チャネルとNa+/Ca2+交換機構の関与2015
- Author(s)
  萩原美帆子, 神林隆一, 高田一唐, 日下部太一, 加藤恵介, 高原章
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-03-18
- Data Source
  KAKENHI-PROJECT-24590669
[Presentation] Characterization of antiarrhythmic potential of renal denervation in the chronic atrioventricular block dogs: Comparison with that of amiodarone.2015
- Author(s)
  小原浩, 高原章, 北原健, 村越伸行, 佐藤明, 青沼和隆, 池田隆徳, 杉山篤
- Organizer
  第79回日本循環器学会学術集会
- Place of Presentation
  グランフロント大阪（大阪府大阪市）
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-15K08598
[Presentation] Involvement of TRPC3 channels in the aldosterone-induced atrial fibrillation in the rat hypertrophy model with chronic volume overload.2015
- Author(s)
  相本恵美, 灘みづき, 高原章
- Organizer
  第79回日本循環器学会学術集会
- Place of Presentation
  グランフロント大阪（大阪府大阪市）
- Year and Date
  2015-04-25
- Data Source
  KAKENHI-PROJECT-15K08598
[Presentation] Cardio-ankle vascular index (CAVI) differentiates pharmacological properties of vasodilators nicardipine and nitroglycerin in anesthetized rabbit.2015
- Author(s)
  Tatsuo Chiba, Mari Yamanaka, Kazuhiro Shimizu, Mao Takahashi, Kohji Shirai, Akira Takahara
- Organizer
  The 25th Scientific Meeting of the European Society of Hypertension
- Place of Presentation
  Milan (Italy)
- Year and Date
  2015-06-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08598
[Presentation] 抗精神病薬が有する催不整脈特性の比較：新規不整脈検出モデルを用いた検討2015
- Author(s)
  神林隆一, 萩原美帆子, 高田一唐, 仲條美佐子, 相本恵美, 高原章
- Organizer
  第133回日本薬理学会関東部会
- Place of Presentation
  柏の葉カンファレンスセンター（千葉県柏市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-15K08598
[Presentation] 動静脈瘻による慢性容量負荷がcarbacholで誘発される心房細動に与える影響2015
- Author(s)
  相本恵美, 福本真利江, 田中光, 高原章
- Organizer
  第133回日本薬理学会関東部会
- Place of Presentation
  柏の葉カンファレンスセンター（千葉県柏市）
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-15K08598
[Presentation] 新規心房細動モデルラットにおける dexamethasone の抗心房細動作用2015
- Author(s)
  梛野健, 相本恵美, 高原章
- Organizer
  第59回日本薬学会関東支部大会
- Place of Presentation
  日本大学薬学部（千葉県船橋市）
- Year and Date
  2015-09-12
- Data Source
  KAKENHI-PROJECT-15K08598
[Presentation] α1-Adrenoceptor stimulation is not essential for nifekalant-induced proarrhythmias under the condition of bradycardia in rabbits.2014
- Author(s)
  萩原美帆子, 高田一唐, 渋田成二, 高原章
- Organizer
  第29回日本不整脈学会学術大会／第31回日本心電学会学術集会合同学術集会
- Place of Presentation
  ザ・プリンスパークタワー東京（東京都港区）
- Year and Date
  2014-07-24
- Data Source
  KAKENHI-PROJECT-24590669
[Presentation] Dahl SラットにおけるL/N型カルシウム拮抗薬シルニジピンの抗心房細動作用：ARBとの併用による効果2014
- Author(s)
  杉野多美, 原田英里, 高原章
- Organizer
  第37回日本高血圧学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-10-17
- Data Source
  KAKENHI-PROJECT-24590669
[Presentation] 動静脈瘻ラット肺静脈心筋の電気生理学的性質2014
- Author(s)
  田中愛弓, 恒岡弥生, 鶴田將人, 中山貴弘, 灘みづき, 相本恵美, 濵口正悟, 行方衣由紀, 高原章, 田中光
- Organizer
  第130回日本薬理学会関東部会
- Place of Presentation
  星薬科大学（東京都品川区）
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-24590669
[Presentation] アルドステロン慢性負荷で生じる心房リモデリングにおけるTRPC3チャネルの関与：動静脈瘻モデルラットを用いた検討2014
- Author(s)
  相本恵美, 灘みづき, 梛野健, 江見遥, 日下部太一, 加藤恵介, 高原章
- Organizer
  第130回日本薬理学会関東部会
- Place of Presentation
  星薬科大学（東京都品川区）
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-24590669
[Presentation] 薬物性不整脈検出におけるウサギ徐脈モデルの有用性2014
- Author(s)
  高田一唐, 萩原美帆子, 渋田成二, 神林隆一, 高原章
- Organizer
  第58回日本薬学会関東支部大会
- Place of Presentation
  昭和薬科大学（東京都町田市）
- Year and Date
  2014-10-04
- Data Source
  KAKENHI-PROJECT-24590669
[Presentation] 麻酔ウサギを用いた心房・心室の電気生理学的特性の同時評価モデル2012
- Author(s)
  米山史陽, 萩原美帆子, 千葉俊樹, 高原章
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-21590602
[Presentation] マウス心筋の再分極過程の特徴:心電図と単相性活動電位を用いた評価2011
- Author(s)
  本間邦恵, 田中光, 高原章
- Organizer
  第55回日本薬学会関東支部大会
- Place of Presentation
  船橋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-21590602
[Presentation] ハロセン麻酔モルモットモデルにおけるジフェンヒドラミンおよびクロペラスチンの心臓電気薬理学的作用2011
- Author(s)
  高原章、藤原香織、大槻篤史、岡貴之、行方衣由紀、田中光
- Organizer
  第124回日本薬理学会関東部会
- Place of Presentation
  東京
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-21590602
[Presentation] シプロフロキサシンの心臓電気薬理学的作用:ハロセン麻酔モルモットモデルによる検討2011
- Author(s)
  藤原香織, 木村伊都紀, 松尾和廣, 田中光, 高原章
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2011
- Place of Presentation
  東京
- Year and Date
  2011-08-31
- Data Source
  KAKENHI-PROJECT-21590602
[Presentation] アドリアマイシン誘発心腎障害モデルラットに対するL/N型カルシウム拮抗薬シルニジピンの効果2011
- Author(s)
  有冨静, 新沼多美, 川上麻衣, 北原吉朗, 高原章
- Organizer
  第34回日本高血圧学会総会
- Place of Presentation
  宇都宮
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-21590602
[Presentation] モルモットおよびラット肺静脈心筋の電気的自発活動とカルシウム動態2011
- Author(s)
  恒岡弥生、秋葉明子、行方衣由紀、高原章、川西徹、田中光
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-21590293
[Presentation] ハロセン麻酔モルモットモデルにおけるジフェンヒドラミンおよびクロペラスチンの心臓電気薬理学的作用2011
- Author(s)
  高原章
- Organizer
  第124回日本薬理学会関東部会
- Place of Presentation
  東京大学農学部弥生講堂(東京都)
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-21590602
[Presentation] モルモット心房におけるoseltamivirの電気生理作用特性2011
- Author(s)
  鈴木早苗, 恒岡弥生, 田中光, 高原章
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2011
- Place of Presentation
  東京
- Year and Date
  2011-08-31
- Data Source
  KAKENHI-PROJECT-21590602
[Presentation] モルモット摘出左心房-肺静脈標本におけるベプリジルの電気生理学的作用2010
- Author(s)
  竹田潔、行方衣由紀、高原章、田中光
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-21590602
[Presentation] Effects of SERCA activators, ellagic acid and gingerol, on diabetes mellitus-induced diastolic dysfunction in isolated murine ventricular myocardia2010
- Author(s)
  Namekata I, Ohara M, Hirota Y, Kawanishi T, Takahara A, Tanaka H
- Organizer
  World Pharma 2010-16th World Congress of Basic and Clinical Pharmacology
- Place of Presentation
  Copenhagen, Danmark
- Year and Date
  2010-07-20
- Data Source
  KAKENHI-PROJECT-21590602
[Presentation] モルモット肺静脈の興奮伝導に対するベプリジルの作用特性2010
- Author(s)
  高原章
- Organizer
  第27回日本心電学会学術集会
- Place of Presentation
  大分
- Data Source
  KAKENHI-PROJECT-21590293
[Presentation] モルモット肺静脈の興奮伝導に対するベプリジルの作用特性2010
- Author(s)
  高原章、竹田潔、恒岡弥生、行方衣由紀、田中光
- Organizer
  第27回日本心電学会学術集会
- Place of Presentation
  大分
- Year and Date
  2010-10-09
- Data Source
  KAKENHI-PROJECT-21590602
[Presentation] モルモット肺静脈心筋の組織・細胞の形態および自発活動2010
- Author(s)
  恒岡弥生、行方衣由紀、高原章、川西徹、田中光
- Organizer
  第19回日本バイオイメージング学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-21590602
[Presentation] モルモット肺静脈心筋における自発活動の電気生理学的および薬理学的性質2010
- Author(s)
  行方衣由紀, 恒岡弥生, 高原章, 田中光
- Organizer
  第115回日本解剖学会総会・全国学術集会
- Place of Presentation
  盛岡
- Year and Date
  2010-03-29
- Data Source
  KAKENHI-PROJECT-21590602
[Presentation] 鎮咳薬クロペラスチンのhERG K+電流に対する作用2010
- Author(s)
  岡貴之、大槻篤史、高原章、行方衣由紀、田中光
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21590602
[Presentation] モルモット肺静脈の興奮伝導に対するベプリジルの作用特性2010
- Author(s)
  高原章
- Organizer
  第27回日本心電学会学術集会
- Place of Presentation
  大分全日空ホテル(大分県)
- Year and Date
  2010-10-09
- Data Source
  KAKENHI-PROJECT-22790262
[Presentation] マウス心室筋の興奮収縮機構の発達変化:薬理学的検討および画像化解析2010
- Author(s)
  行方衣由紀、川上悠子、濱口省吾、川西徹、高原章、田中光
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21590293
[Presentation] 動静脈瘻心肥大ラットの心房におけるカルバコールの電気生理学的作用2010
- Author(s)
  福本真利江、行方衣由紀、高原章、田中光
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-21590602
[Presentation] モルモット肺静脈心筋の電気的自発活動およびカルシウム動態の検討2010
- Author(s)
  恒岡弥生、行方衣由紀、高原章、田中光
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21590293
[Presentation] モルモット肺静脈の興奮伝導に対するベプリジルの作用特性2010
- Author(s)
  高原章
- Organizer
  第27回日本心電学会学術集会
- Place of Presentation
  大分全日空ホテルオアシスタワー(大分県)
- Year and Date
  2010-10-09
- Data Source
  KAKENHI-PROJECT-21590602
[Presentation] モルモット肺静脈心筋の電気的自発活動およびカルシウム動態の検討2010
- Author(s)
  恒岡弥生、行方衣由紀、高原章、田中光
- Organizer
  第83回日本薬理学会年会
- Place of Presentation
  大阪
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-21590602
[Presentation] Effects of SERCA activators, ellagic acid and gingerol, on diabetes mellitus-induced diastolic dysfunction in isolated murine ventricular myocardia2010
- Author(s)
  Iyuki Namekata, Minato Ohhara, Yoshitaka Hirota, Toru Kawanishi, Akira Takahara, Hikaru Tanaka
- Organizer
  The 16th World Congress of Basic and Clinical Pharmacology(World Pharma 2010)
- Place of Presentation
  Copenhagen, Denmark
- Data Source
  KAKENHI-PROJECT-21590293
[Presentation] モルモット肺静脈心筋の組織・細胞の形態および自発活動2010
- Author(s)
  恒岡弥生、行方衣由紀、高原章、川西徹、田中光
- Organizer
  第19回日本バイオイメージング学会学術集会
- Place of Presentation
  慶應義塾大学日吉キャンパス
- Data Source
  KAKENHI-PROJECT-21590293
[Presentation] Electropharmacological analysis of triggered activity in the pulmonary vein myocardium of the guinea pig2010
- Author(s)
  Takahara A, Sugimoto T, Takeda K, Namekata I, Tanaka H
- Organizer
  World Pharma 2010-16th World Congress of Basic Clinical Pharmacology
- Place of Presentation
  Copenhagen, Danmark
- Year and Date
  2010-07-22
- Data Source
  KAKENHI-PROJECT-21590602
[Presentation] モルモット肺静脈の興奮伝導に対するベプリジルの作用特性2010
- Author(s)
  高原章
- Organizer
  第27回日本心電学会学術集会
- Place of Presentation
  大分全日空ホテル(大分)
- Year and Date
  2010-10-09
- Data Source
  KAKENHI-PROJECT-22790262
[Presentation] Electropharmacological analysis of triggered activity in the pulmonary vein myocardium of the guinea pig.2010
- Author(s)
  高原章
- Organizer
  WorldPharma2010-16th World Congress of Basic Clinical Pharmacology
- Place of Presentation
  Bella Center Copenhagen, Denmark
- Year and Date
  2010-07-22
- Data Source
  KAKENHI-PROJECT-21590602
[Presentation] モルモット肺静脈心筋における自発活動の電気生理学的および薬理学的性質2010
- Author(s)
  行方衣由紀、恒岡弥生、高原章、田中光
- Organizer
  第115回日本解剖学会総会・全国学術集会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-21590293
[Presentation] Ca^<2+>拮抗薬の徐脈作用に関与するCa^<2+>チャネル分子種の検討: efonidipine光学異性体Cav1.2, Cav1.3, Cav3.1チャネルに対する作用2010
- Author(s)
 行方衣由紀、恒岡弥生、竹田潔、高原章、田中光
- Organizer
 生理研研究会「イオンチャネル・トランスポーターと心血管機能:細胞機能の分子機序とその統合的理解」
- Place of Presentation
 岡崎生理学研究所
- Data Source
 KAKENHI-PROJECT-21590293
[Presentation] モルモット肺静脈心筋の自発活動へのNa^+/Ca^<2+>交換機構と筋小胞体の寄与2009
- Author(s)
 恒岡弥生、杉本貴彦、竹田潔、行方衣由紀、高原章、田中光
- Organizer
 第120回日本薬理学会関東部会
- Place of Presentation
 東京
- Year and Date
 2009-07-11
- Data Source
 KAKENHI-PROJECT-21590602
[Presentation] モルモット肺静脈の心筋活動電位に対するベプリジルの影響 : 左心房に対する作用との比較2009
- Author(s)
  竹田潔、杉本貴彦、行方衣由紀、高原章、田中光
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-18
- Data Source
  KAKENHI-PROJECT-19590532
[Presentation] 肺静脈の電気的興奮を制御する心房細動治療標的分子に関する研究2009
- Author(s)
  高原章、行方衣由紀、田中光
- Organizer
  生体機能と創薬シンポジウム2009
- Place of Presentation
  東京
- Year and Date
  2009-08-26
- Data Source
  KAKENHI-PROJECT-21590293
[Presentation] Chronic atrioventricular(AV)block sensitizes monkey heart for drug-induced Torsades de Pointes(TdP)via biochemicalbiochemical, anatomical and electrophysiological remodelings2009
- Author(s)
  Sugiyama A, Nakamura Y, Saitoh M, Takahara A, Sakamoto K, Sasaki H, Hombo T, Wakasa Y, Nomura M
- Organizer
  The 2007 Autumn Meeting of The British Society for Cardiovascular Research
- Place of Presentation
  London
- Year and Date
  2009-09-24
- Data Source
  KAKENHI-PROJECT-19590532
[Presentation] 鎮咳薬クロブチノールの催不整脈特性:E-4031との比較2009
- Author(s)
  高原章
- Organizer
  第121回日本薬理学会関東部会
- Place of Presentation
  東京女子医科大学
- Year and Date
  2009-10-10
- Data Source
  KAKENHI-PROJECT-21590293
[Presentation] Electrophysiological and pharmacological properties of the isolated guinea-pig pulmonary vein myocardium2009
- Author(s)
  Iyuki Namekata, Yayoi Tsuneoka, Takahiko Sugimoto, Kiyoshi Takeda, Toru Kawanishi, Ryu Nakamura, Akira Takahara, Hikaru Tanaka
- Organizer
  The 36th Congress of the International Union of Physiological Sciences(IUPS2009)
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21590293
[Presentation] Electro-physiological and pharmacological properties of the isolated guinea-pig pulmonary vein myocardium2009
- Author(s)
  Namekata I, Tsuneoka Y, Sugimoto T, Takeda K, Kawanishi T, Nakamura R, Takahara A, Tanaka H
- Organizer
  The 36th Congress of the International Union of Physiological Sciences
- Place of Presentation
  Kyoto
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-21590602
[Presentation] 鎮咳薬クロブチノールの催不整脈特性:E-4031との比較2009
- Author(s)
  高原章
- Organizer
  第121回日本薬理学会関東部会
- Place of Presentation
  東京女子医科大学
- Year and Date
  2009-10-10
- Data Source
  KAKENHI-PROJECT-20890233
[Presentation] ハロセン麻酔モルモットモデルにおける鎮咳薬クロブチノールの心筋再分極相に与える作用 : 小動物用MAP記録カテーテルによる評価2009
- Author(s)
  高原章、中村真理子、仙道晶子、行方衣由紀、田中光
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-18
- Data Source
  KAKENHI-PROJECT-19590532
[Presentation] モルモット肺静脈心筋の自発活動へのNa^+/Ca^<2+>交換機構と筋小胞体の寄与2009
- Author(s)
 恒岡弥生、杉本貴彦、竹田潔、行方衣由紀、高原章、田中光
- Organizer
 第120回日本薬理学会
- Place of Presentation
 関東部会東京
- Year and Date
 2009-07-11
- Data Source
 KAKENHI-PROJECT-21590293
[Presentation] モルモット肺静脈に誘発される撃発活動の電気生理学的特性2009
- Author(s)
  高原章、杉本貴彦、行方衣由紀、田中光
- Organizer
  第26回日本心電学会学術集会
- Place of Presentation
  京都
- Year and Date
  2009-07-02
- Data Source
  KAKENHI-PROJECT-21590293
[Presentation] モルモット肺静脈心筋における自発的電気活動の発生機序の検討2009
- Author(s)
  行方衣由紀、恒岡弥生、竹田潔、高原章、田中光
- Organizer
  次世代を担う創薬・医療薬理シンポジウム2009
- Place of Presentation
  東京
- Year and Date
  2009-08-24
- Data Source
  KAKENHI-PROJECT-21590293
[Presentation] モルモット肺静脈に誘発される撃発活動の電気薬理学的特性2009
- Author(s)
  高原章、杉本貴彦、行方衣由紀、田中光
- Organizer
  第26回日本心電学会学術集会
- Place of Presentation
  京都
- Year and Date
  2009-07-02
- Data Source
  KAKENHI-PROJECT-21590602
[Presentation] 肺静脈の電気的興奮を制御する心房細動治療標的分子に関する研究2009
- Author(s)
  高原章
- Organizer
  生体機能と創薬シンポジウム2009
- Place of Presentation
  昭和大学
- Year and Date
  2009-08-26
- Data Source
  KAKENHI-PROJECT-21590293
[Presentation] 鎮咳薬クロブチノールの催不整脈特性: E-4031との比較2009
- Author(s)
  高原章、中村真理子、佐々木梨江子、仙道晶子、岡貴之、大槻篤史、櫻井悠紀子、行方衣由紀、田中光
- Organizer
  第121回日本薬理学会関東部会
- Place of Presentation
  東京
- Year and Date
  2009-10-10
- Data Source
  KAKENHI-PROJECT-21590602
[Presentation] ピルジカイニド経皮貼付剤の薬理作用と電気生理学的効果:慢性房室ブロック犬心房での検討2009
- Author(s)
  岩崎宏、高原章、中村裕二、佐藤吉沖、永井猛、新開規弘、杉山篤
- Organizer
  第121回日本薬理学会関東部会
- Place of Presentation
  東京
- Year and Date
  2009-10-10
- Data Source
  KAKENHI-PROJECT-21590602
[Presentation] ハロセン麻酔モルモットモデルにおける鎮咳薬クロブチノールの心筋再分極相に与える影響 : 小動物用MAP記録カテーテルによる評価2009
- Author(s)
  高原章
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20890233
[Presentation] モルモット肺静脈心筋における自発的電気活動の発生機序の解明:組織および単離細胞を用いた検討2009
- Author(s)
  行方衣由紀、恒岡弥生、竹田潔、高原章、田中光
- Organizer
  生理研研究会「イオンチャネル・トランスポーターと心血管機能:細胞機能の分子機序とその統合的理解」
- Place of Presentation
  岡崎生理学研究所
- Data Source
  KAKENHI-PROJECT-21590293
[Presentation] ハロセン麻酔モルモットモデルにおける鎮咳薬クロブチノールの心筋再分極相に与える作用 : 小動物用MAP記録カテーテルによる評価.2009
- Author(s)
  高原章
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-03-18
- Data Source
  KAKENHI-PROJECT-19590532
[Presentation] モルモット肺静脈心筋の電気活動とCa^<2+>動態2009
- Author(s)
 恒岡弥生、行方衣由紀、高原章、田中光
- Organizer
 第3回先端分子薬理研究会
- Place of Presentation
 慶應義塾大学薬学部
- Year and Date
 2009-11-28
- Data Source
 KAKENHI-PROJECT-21590293
[Presentation] 肺静脈の電気的興奮を制御する心房細動治療標的分子に関する研究2009
- Author(s)
  高原章
- Organizer
  生体機能と創薬シンポジウム2009
- Place of Presentation
  昭和大学
- Year and Date
  2009-08-26
- Data Source
  KAKENHI-PROJECT-20890233
[Presentation] Chronic atrioventricular block abbreviated the action potential duration of canine pulmonary vein myocardium.2008
- Author(s)
  高原章
- Organizer
  第72回日本循環器学会学術集会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2008-03-29
- Data Source
  KAKENHI-PROJECT-19590532
[Presentation] 慢性房室ブロック犬心筋におけるK^+チャネルmRNAの発現抑制2008
- Author(s)
  高原章、我妻広貴、有冨静、今田智之、秋江靖樹、杉山篤
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-18
- Data Source
  KAKENHI-PROJECT-19590532
[Presentation] モルモット肺静脈心筋における自発的電気活動の発生機序 : 選択的Na+^/Ca^<2+>交換機構阻害薬SEA0400を用いた検討2008
- Author(s)
 行方衣由紀、恒岡弥生、杉本貴彦、竹田潔、島田英朗、高原章、田中光
- Organizer
 第18回日本循環薬理学会
- Place of Presentation
 千葉
- Year and Date
 2008-11-21
- Data Source
 KAKENHI-PROJECT-19590532
[Presentation] モルモット摘出肺静脈の活動電位に対するカリウムチャネル抑制薬の影響2008
- Author(s)
  杉本貴彦、野内秀明、高原章、田中光
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-18
- Data Source
  KAKENHI-PROJECT-19590532
[Presentation] Arrhythmogenic property of the pulmonary vein myocardium in guinea pigs as a source of atrial fibrillation. The 9th World Conference on Clinical2008
- Author(s)
  Takahara A, Sugimoto T, Takeda K, Tsuneoka Y, Kudo N, Namekata I, Tanaka H.
- Organizer
  Pharmacology and Therapeutics
- Place of Presentation
  Quebec
- Year and Date
  2008-08-01
- Data Source
  KAKENHI-PROJECT-19590532
[Presentation] ventricular myocardia2008
- Author(s)
  Namekata I, Ohhara M, Hirota Y, Fukumoto M, Kawanishi T, Takahara A, Tanaka H.
- Organizer
  The 25th Annual Meeting of ISHR Japanese Section
- Place of Presentation
  Yokohama
- Year and Date
  2008-12-05
- Data Source
  KAKENHI-PROJECT-19590532
[Presentation] 心筋の興奮・収縮機構の多様性2008
- Author(s)
  田中光、行方衣由紀、野内秀明、高原章
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-18
- Data Source
  KAKENHI-PROJECT-19590532
[Presentation] L/T型カルシウム拮抗薬エホニジピンの反射性頻脈に対する抑制効果2008
- Author(s)
  宇野洋司、高原章、田中光
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-18
- Data Source
  KAKENHI-PROJECT-19590532
[Presentation] Chronic atrioventricular block abbreviated the action potential duration of canine pulmonary vein myocardium2008
- Author(s)
  高原章、野内秀明、田中光、杉山篤
- Organizer
  第72回日本循環器学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2008-03-29
- Data Source
  KAKENHI-PROJECT-19590532
[Presentation] 慢性房室ブロック犬心筋におけるK^+チャネルmRNA発現抑制2008
- Author(s)
  高原章
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-03-18
- Data Source
  KAKENHI-PROJECT-19590532
[Presentation] Arrhythmogenic Property of the Pulmonary Vein Myocardium in Guinea Pigs as a Source of Atrial Fibrillation.2008
- Author(s)
  Akira Takahara
- Organizer
  The 9th World Conference on Clinical Pharmacology and Therapeutics
- Place of Presentation
  Quebec, Canada
- Data Source
  KAKENHI-PROJECT-20890233
[Presentation] Arrhythmogenic Property of the Pulmonary Vein Myocardium in Guinea Pigs as a Source of Atrial Fibrillation.2008
- Author(s)
  高原章
- Organizer
  The 9th World Conference on Clinical Pharmacology and Therapeutics
- Place of Presentation
  Quebec City Convention Centre
- Year and Date
  2008-08-01
- Data Source
  KAKENHI-PROJECT-19590532
[Presentation] 肺静脈自動能の発生機序の検討2008
- Author(s)
  行方衣由紀、恒岡弥生、杉本貴彦、竹田潔、長治緑、川西徹、中村竜、高原章、田中光
- Organizer
  第17回日本バイオイメージング学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19590532
[Presentation] 慢性完全房室ブロックモデル動物を用いた薬物性QT延長症候群のリスク評価2007
- Author(s)
  杉山篤、佐藤吉沖、高原章
- Organizer
  第24回日本心電学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2007-10-06
- Data Source
  KAKENHI-PROJECT-19590532
[Presentation] モルモット肺静脈の電気生理学的特性2007
- Author(s)
  島田英朗、杉本貴彦、高原章、竹田潔、恒岡弥生、行方衣由紀、重信弘毅、田中光
- Organizer
  第24回日本心電学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2007-10-06
- Data Source
  KAKENHI-PROJECT-19590532
[Presentation] Utility of the embryonic chick ventricle as a new model to detect QT-interval prolonging drugs2007
- Author(s)
  Namekata I, Takahara A, Nouchi H, Kimata M, Tsuruoka N, Shigenobu K, Tanaka H
- Organizer
  The 2007 Autumn Meeting of The British Society for Cardiovascular Research
- Place of Presentation
  London
- Year and Date
  2007-09-24
- Data Source
  KAKENHI-PROJECT-19590532
[Presentation] 新規サル催不整脈モデルを用いたtorsades de pointes(TdP)リスク評価系の確立2007
- Author(s)
  坂本憲吾、大谷光嗣、若狭芳男、高原章、杉山篤
- Organizer
  第34回日本トキシコロジー学会学術年会
- Place of Presentation
  東京
- Year and Date
  2007-06-28
- Data Source
  KAKENHI-PROJECT-19590532
[Presentation] 鶏胚心筋を用いた薬物の催不整脈性評価法2007
- Author(s)
  野内秀明、木股幹雄、桐生直明、高原章、田中光
- Organizer
  第117回日本薬理学会関東部会
- Place of Presentation
  東京
- Year and Date
  2007-10-06
- Data Source
  KAKENHI-PROJECT-19590532
[Presentation] Embryonic chick myocardium as a sensitive model for prediction of drug-induced QT-interval prolongation2007
- Author(s)
  Namekata I, Takahara A, Nouchi H, Kimata M, Shigenobu K, Tanaka H.
- Organizer
  The 7th Annual Meeting of the Safety Pharmacology Society
- Place of Presentation
  Edinburgh
- Year and Date
  2007-09-20
- Data Source
  KAKENHI-PROJECT-19590532
[Presentation] ハロセン麻酔モルモットモデルにおけるジフェンヒドラミンおよび鎮咳薬クロペラスチンのhERG K+チャネルおよび心電図QT間隔に対する作用
- Author(s)
  高原章
- Organizer
  第29回日本心電学会学術集会
- Place of Presentation
  幕張メッセ国際会議場（千葉）
- Data Source
  KAKENHI-PROJECT-22790262
[Presentation] ウサギCAVI計測モデルにおける血管拡張薬ニトログリセリンとニカルジピンの作用の相違．
- Author(s)
  千葉達夫、山中茉莉、佐々木英久、清水一寛、高橋真生、白井厚治、高原章
- Organizer
  第36回日本高血圧学会総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Data Source
  KAKENHI-PROJECT-24590669
[Presentation] Electrophysiological characteristics of atrial remodlings in the rat abdominal aortocaval fistula hypertrophy model.
- Author(s)
  八木啓太, 江沢亜耶, 福本真理江, 恒岡弥生, 濱口正悟, 長谷川健志, 久世哲郎, 千葉俊樹, 灘みづき, 行方衣由紀, 田中光, 高原章
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場（福岡県）
- Data Source
  KAKENHI-PROJECT-24590669
[Presentation] The L/N-type Ca2+ Channel Blocker Cilnidipine Effectively Suppressed the Cardiac Histological Remodeling and Dysfunction in the High-salt-fed Rats
- Author(s)
  新沼多美, 原田英里, 高原章
- Organizer
  第77回日本循環器学会学術集会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-24590669
[Presentation] オセルタミビルは高頻度刺激により誘発された心房細動を抑制する：ラット動静脈瘻心拡大モデルを用いた検討．
- Author(s)
  灘みづき、相本恵美、八木啓太、江沢亜耶、杉山篤、高原章
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-24590669
[Presentation] Dahl Sラットを用いた心房細動誘発モデルにおけるL/N型カルシウム拮抗薬シルニジピンの作用．
- Author(s)
  原田英里、杉野多美、西村麻衣、高原章
- Organizer
  第36回日本高血圧学会総会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Data Source
  KAKENHI-PROJECT-24590669
[Presentation] 鎮咳薬クロペラスチンのhERG Kチャネルおよび心電図QT間隔に対する作用
- Author(s)
  高原章, 藤原香織, 岡貴之, 大槻篤史, 行方衣由紀, 田中光
- Organizer
  第29回日本心電学会学術集会
- Place of Presentation
  幕張メッセ（千葉県）
- Data Source
  KAKENHI-PROJECT-24590669
[Presentation] 動静脈瘻による慢性容量負荷が心房の電気生理学的特性に与える影響
- Author(s)
  八木啓太, 高原章
- Organizer
  第29回日本心電学会学術集会
- Place of Presentation
  幕張メッセ（千葉県）
- Data Source
  KAKENHI-PROJECT-24590669
[Presentation] 麻酔ウサギを用いたアドレナリンα受容体作用薬を使用しない薬物誘発性不整脈モデルの検討．
- Author(s)
  萩原美帆子、渋田成二、高田一唐、高原章
- Organizer
  第30回日本心電学会年次学術集会
- Place of Presentation
  リンクステーションホール青森（青森県青森市）
- Data Source
  KAKENHI-PROJECT-24590669
[Presentation] 心房に対するオセルタミビルの電気生理学的作用：モルモット単離心房標本による検討.
- Author(s)
  萩原美帆子、鈴木早苗、野崎修平、杉山篤、高原章
- Organizer
  第128回日本薬理学会関東部会
- Place of Presentation
  早稲田大学（東京都新宿区）
- Data Source
  KAKENHI-PROJECT-24590669
[Presentation] シプロヘプタジンの心臓電気薬理学的作用：ハロセン麻酔モルモットモデルによる検討
- Author(s)
  大室直樹, 藤原香織, 高原章
- Organizer
  第126回日本薬理学会関東部会
- Place of Presentation
  北里大学薬学部（東京都）
- Data Source
  KAKENHI-PROJECT-24590669
[]
[]
[]

1. NAMEKATA Iyuki (30510309)

# of Collaborated Projects: 4 results

# of Collaborated Products: 45 results
2. SUGIYAMA Atsushi (60242632)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
3. TANAKA Hikaru (40236617)

# of Collaborated Projects: 3 results

# of Collaborated Products: 29 results
4. KAWANISHI Toru (40124383)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
5. TANAKA Naoko (40184353)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Sato Akira (30528469)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. AONUMA Kazutaka (10375488)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. MURAKOSHI Nobuyuki (80447218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 相本恵美 (20756358)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
10. Machino Takeshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 曹新

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAKAHARA Akira 高原 章

高原 章 タカハラ アキラ

Research Projects

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Co-Researchers

Electrophysiological analysis of proarrhythmic properties of volatile anesthetics using an originally developed arrhythmogenic modelPrincipal Investigator

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ANALYSIS OF THERAPEUTIC TARGET MOLECULES FOR SUSTAINED ATRIAL FIBRILLATION CAUSED BY CHRONIC VOLUME OVERLOADPrincipal Investigator

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RENAL DENERVATION: NOVEL THERAPY FOR RESISTANT HYPERTENSION

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ANALYSIS OF THERAPEUTIC TARGET MOLECULES FOR ARRHYTHMIAS IN THE NEWLY DEVELOPED ANIMAL MODEL OF SUSTAINED ATRIAL FIBRILLATIONPrincipal Investigator

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Spatio-temporal analysis of intracellularcalcium oscillation in the pulmonary vein myocardium

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The role of intracellular calcium and sodium-calcium exchanger in the automaticity of pulmonary vein myocardium.

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INVESTIGATION OF THERAPEUTIC TARGET MOLECULES FOR ATRIAL FIBRILLATION REGULATING ELECTRICAL EXCITATION IN PULMONARY VEINPrincipal Investigator

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Fluorescence imaging analysis of Na^+/Ca^<2+> exchanger dynamics in myocardial ischemia reperfusion injury

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PHARMACOTHERAPEUTIC STRATEGY FOR PREVENTION OF CARDIAC SUDDEN DEATH CAUSED BY VENTRICULAR REPOLARIZATION ABNORMALITYPrincipal Investigator

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[Book] Antihypertensive Drugs2012

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[Journal Article] Evaluating the relationship between ocular blood flow and systemic organ blood flow in hemorrhagic shock using a rabbit model2024

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[Journal Article] The role of arterial stiffness in the onset of Takotsubo cardiomyopathy observed with noradrenaline administration and intracranial blood injection in rabbits2023

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[Journal Article] Differential Effects of Ca<sup>2+</sup> Channel Blockers Nifedipine and Cilnidipine on Arterial Elasticity in the Aortic and Femoral Arterial Segments of Anesthetized Rabbits2023

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TAKAHARA Akira 高原章

高原章タカハラアキラ