(Shimada) (Tadayuki) 島田忠之

… Alternative Names

島田忠之シマダタダユキ

SHIMADA Tadayuki 島田忠之

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Researcher Number	80379552
Other IDs
Affiliation (Current)	2025: 公益財団法人東京都医学総合研究所, 脳・神経科学研究分野, 主席研究員 2025: 公益財団法人東京都医学総合研究所, 臨床医科学研究分野, 主席研究員
Affiliation (based on the past Project Information) *help	2022 – 2023: 公益財団法人東京都医学総合研究所, 脳・神経科学研究分野, 主席研究員 2020: 公益財団法人東京都医学総合研究所, 精神行動医学研究分野, 主席研究員 2019: 公益財団法人東京都医学総合研究所, 脳発達・神経再生分野, 主席研究員 2017 – 2018: 公益財団法人東京都医学総合研究所, 脳発達・神経再生研究分野, 主席研究員 2014 – 2015: 公益財団法人東京都医学総合研究所, 脳発達・神経再生分野, 主席研究員 … More 2013: 公益財団法人東京都医学総合研究所, 脳発達・神経再生研究分野, 主席研究員 2012: 公益財団法人東京都医学総合研究所, 脳発達・神経再生分野, 研究員 2010: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 助教 2007 – 2008: Nara Institute of Science and Technology, Biological Sciences, Assistant Professor 2006: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 特任助手 2005 – 2006: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 助手 Less
Review Section/Research Field	Principal Investigator Neuroscience in general / Basic Section 46030:Function of nervous system-related / Nerve anatomy/Neuropathology / Neuroscience in general Except Principal Investigator Neuroscience in general / Biological Sciences
Keywords	Principal Investigator 軸索分枝形成 / 細胞骨格 / 細胞内局在制御 / 脳・神経 / 発生分化 / 神経科学 / 自閉症 / 社会行動 / 神経細胞形態 / グリア神経相互作用 … More / 樹状突起スパイン形態 / シナプス形成 / 細胞外マトリクス / 結節性硬化症 / グリア神経間相互作用 / 神経解剖学 / セロトニン・ノルアドレナリン / 神経軸索分枝形成 / ストレス応答 / うつ・不安障害 / うつ・不安行動 / ストレス / FGFシグナル / セロトニン / うつ・不安 / 神経細胞 / 軸索伸長、分枝形成 / 神経回路網 / 神経活動 / FGF / 神経可塑性 / ＦＧＦシグナル / 神経回路 / 軸索分枝 / てんかん / 形態形成 / 細胞接着 / 軸索 / 細胞運動 / 細胞極性 / シグナル伝達 / プロテオーム … More Except Principal Investigator Shootin1 / 神経細胞 / 極性 / 樹状突起 / 軸索 / L1 / 成長円錐 / アクチン / PI 3-kinase / ノックアウトマウス / Shootinl / Growth cone / Actin / Dendrite / Axon / Cell polarity / Neuron / Wave / Netrin-1 / クラッチ分子 / プロテオミクス / 再生医療 / 神経回路 / Singar / システムバイオロジー / システムズバイオロジー / 対称性破壊 / 形態形成 Less

神経-グリア間相互作用の調節を通じた、社会行動の制御メカニズムPrincipal Investigator
- Principal Investigator
  
  島田忠之
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46030:Function of nervous system-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Regulatory mechanism of depression and anxiety via the control of axonal branch formationPrincipal Investigator
- Principal Investigator
  
  SHIMADA Tadayuki
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Role of clutch protein shootin1 in activity-dependent axonal elongationPrincipal Investigator
- Principal Investigator
  
  SHIMADA Tadayuki
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Mechanism of Neuronal Polarization Mediated by Shootin and Its Roles in the Brain
- Principal Investigator
  
  INAGAKI Naoyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Nara Institute of Science and Technology
新規タンパク質shootin1を中心とした軸索伸長を司る基本メカニズムの解析Principal Investigator
- Principal Investigator
  
  島田忠之
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Nara Institute of Science and Technology
細胞が非対称性を獲得する原理の分子レベルおよび数理・数式レベルでのモデル構築
- Principal Investigator
  
  INAGAKI Naoyuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
神経細胞が過剰な軸索の形成を抑制する分子機構の解析
- Principal Investigator
  
  稲垣直之
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
Analysis of a Novel Protein Shootin1, which is involved in organization of an asymmetric signal for neuronal polarization
- Principal Investigator
  
  INAGAKI Naoyuki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Nara Institute of Science and Technology
神経細胞の極性形成をつかさどる新規タンパク質shootinの機能解析Principal Investigator
- Principal Investigator
  
  島田忠之
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Nara Institute of Science and Technology

[Journal Article] Spine morphogenesis and synapse formation in tubular sclerosis complex models2022
- Author(s)
  Shimada Tadayuki、Yamagata Kanato
- Journal Title
  
  Frontiers in Molecular Neuroscience
  
  Volume: 15 Pages: 1019343-1019343
- DOI
  10.3389/fnmol.2022.1019343
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06493, KAKENHI-PROJECT-22K07949, KAKENHI-PROJECT-18H02536
[Journal Article] Syntenin: PDZ Protein Regulating Signaling Pathways and Cellular Functions2019
- Author(s)
  Tadayuki Shimada, Shin Yasuda, Hiroko Sugiura, and Kanato Yamagata.
- Journal Title
  
  International Journal of Molecular Science
  
  Volume: 20(17) Issue: 17 Pages: 4171-4171
- DOI
  10.3390/ijms20174171
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07086, KAKENHI-PROJECT-18H02536
[Journal Article] Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance.2018
- Author(s)
  Baba K, Yoshida W, Toriyama M, Shimada T, Manning CF, Saito M, Kohno K, Trimmer JS, Watanabe R, Inagaki N.
- Journal Title
  
  eLife
  
  Volume: 7
- DOI
  10.7554/elife.34593
- NAID
  120006500834
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07086, KAKENHI-PROJECT-17H05003
[Journal Article] Pentylenetetrazole-Induced Kindling Mouse Model.2018
- Author(s)
  Shimada T, Yamagata K.
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: 12 Issue: 136 Pages: 136-136
- DOI
  10.3791/56573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K07086, KAKENHI-PROJECT-18H02536
[Journal Article] Pentylenetetrazole-Induced Kindling Mouse Model2018
- Author(s)
  Tadayuki Shimada and *Kanato Yamagata
- Journal Title
  
  Journal of Visualized Experiments
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07086
[Journal Article] Role of neuritin in retinal ganglion cell death in adult mice following optic nerve injury.2018
- Author(s)
  Azuchi Y, Namekata K, Shimada T, Guo X, Kimura A, Harada C, Saito A, Yamagata K, Harada T.
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 10132-10132
- DOI
  10.1038/s41598-018-28425-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07086, KAKENHI-PROJECT-17K07123, KAKENHI-PROJECT-18H02536, KAKENHI-PROJECT-16K07076, KAKENHI-PROJECT-16K08635
[Journal Article] 自閉症におけるシナプス異常の新知見2018
- Author(s)
  山形　要人、杉浦　弘子、島田　忠之
- Journal Title
  
  細胞
  
  Volume: 50 Pages: 17-20
- Data Source
  KAKENHI-PROJECT-17K07086
[Journal Article] Neuritin mediates activity-dependent axonal branch formation in part via FGF signaling2016
- Author(s)
  Tadayuki Shimada, Tomoyuki Yoshida and Kanato Yamagata
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 36
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24700349
[Journal Article] Collapsin response mediator protein 4 regulates growth cone dynamics through the actin and microtubule cytoskeleton2014
- Author(s)
  Mohamad R. Khazaei, Marie-Pier Girouard, Ricardo Alchini, Stephan Ong Tone, Tadayuki Shimada, Susanne Bechstedt, Mitra Cowan, Dominique Guillet, Paul W. Wiseman, Gary Brouhard, Jean Francois Cloutier and Alyson E. Fournier.
- Journal Title
  
  Journal of Biochemistry
  
  Volume: 289 Issue: 43 Pages: 30133-30143
- DOI
  10.1074/jbc.m114.570440
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700349
[Journal Article] Activation of Rheb, but not of mTORC1, impairs spine synapse morphogenesis in tuberous sclerosis complex.2014
- Author(s)
  Yasuda S, Sugiura H, Katsurabayashi S, Shimada T, Tanaka H, Takasaki K, Iwasaki K, Kobayashi T, Hino O, Yamagata K.
- Journal Title
  
  Sci Rep.
  
  Volume: 4 Issue: 1 Pages: 5155-5155
- DOI
  10.1038/srep05155
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590300, KAKENHI-PROJECT-24500452, KAKENHI-PROJECT-24659093, KAKENHI-PROJECT-24700349, KAKENHI-PUBLICLY-25110737, KAKENHI-PROJECT-25293239, KAKENHI-PROJECT-25350988, KAKENHI-PROJECT-25670196, KAKENHI-PROJECT-221S0001
[Journal Article] Role of inflammatory mediators in the pathogenesis of epilepsy.2014
- Author(s)
  Shimada T, Takemiya T, Sugiura H, Yamagata K
- Journal Title
  
  Mediators Inflamm.
  
  Volume: 2014 Pages: 901902-901902
- DOI
  10.1155/2014/901902
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24659093, KAKENHI-PROJECT-24700349, KAKENHI-PUBLICLY-25110737, KAKENHI-PROJECT-25293239, KAKENHI-PROJECT-25461563
[Journal Article] Neuroprotective function of 14-3-3 proteins in neurodegeneration.2013
- Author(s)
  Shimada, T., Fournier, A.E., and Yamagata, K.
- Journal Title
  
  BioMed. Res. Int.
  
  Volume: 2013 Pages: 564534-564534
- DOI
  10.1155/2013/564534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659093, KAKENHI-PROJECT-24700349, KAKENHI-PUBLICLY-25110737, KAKENHI-PROJECT-25293239
[Journal Article] Neuritin: A therapeutic candidate for promoting axonal regeneration.2013
- Author(s)
  Shimada, T., Sugiura, H., and Yamagata K.
- Journal Title
  
  World J. Neurol.
  
  Volume: 3 Issue: 4 Pages: 138-143
- DOI
  10.5316/wjn.v3.i4.138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659093, KAKENHI-PROJECT-24700349, KAKENHI-PUBLICLY-25110737, KAKENHI-PROJECT-25293239
[Journal Article] A diffusion-based neurite length sensing mechanism involved in neuronal symmetry-breaking2010
- Author(s)
  Toriyama M., Sakumura Y., Shimada, T., Ishii, S., Inagaki N.
- Journal Title
  
  Mol.Syst.Biol. 6
  
  Pages: 394-394
- NAID
  120005830837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300111
[Journal Article] A diffusion-based neurite length sensing mechanism involved in neuronal symmetry-breaking2010
- Author(s)
  Toriyama, M., Sakumura, Y., Shimada, T., Ishii, S., Inagaki, N
- Journal Title
  
  Mol.Syst.Biol.
  
  Volume: 6 Pages: 394-394
- NAID
  120005830837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300111
[Journal Article] Shootin1 interacts with actin retrograde flow and L1-CAM to promote axon outgrowth2008
- Author(s)
  Shimada T., Toriyama M., Uemura K., Kamiguchi H., Sugiura T., Watanabe N.Inagaki N.
- Journal Title
  
  J.Cell Biol. 181
  
  Pages: 817-829
- NAID
  120005830838
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300111
[Journal Article] Shootinl interacts with actin retrograde flow and L1-CAM topromote axon outgrowth2008
- Author(s)
  T. Shimada
- Journal Title
  
  Journal of Cell Biology (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19700291
[Journal Article] Shootin1 interacts with actin retrograde flow and L1-CAM to promote axon outgrowth2008
- Author(s)
  Shimada, T., Toriyama, M., Uemura, K., Kamiguchi, H., Sugiura, T., Watanabe, N. and Inagaki, N.
- Journal Title
  
  J. Cell Biol. (印刷中)
- NAID
  120005830838
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300107
[Journal Article] Shootin1 interacts with actin retrograde flow and L1-CAM to promote axon outgrowth2008
- Author(s)
  T. Shimada
- Journal Title
  
  Journal of Cell Biology 181(印刷中)
- NAID
  120005830838
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19700291
[Journal Article] Shootin1 interacts with actin retrograde flow and L1-CAM to promote axon outgrowth2008
- Author(s)
  Shimada, T., Toriyama, M., Uemura, K., Kamiguchi, H., Sugiura, T., Watanabe, N., Inagaki, N
- Journal Title
  
  J. Cell Biol (in press)
- NAID
  120005830838
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300107
[Journal Article] Shootinl interacts with actin retrograde flow and L1-CAM to promote axon outgrowth2008
- Author(s)
  Shimada, T
- Journal Title
  
  J. Cell Biol. 181
  
  Pages: 817-829
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300111
[Journal Article] Shootin1による神経細胞の対称性破壊と極性形成2007
- Author(s)
  稲垣直之、鳥山道則、島田忠之
- Journal Title
  
  脳21 10
  
  Pages: 107-109
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300107
[Journal Article] 神経極性形成とShootin1のフィードバックループ2007
- Author(s)
  稲垣直之、鳥山道則、島田忠之
- Journal Title
  
  生化学 79
  
  Pages: 799-802
- NAID
  10019550731
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300107
[Journal Article] Neuronal polarity formation and feedback loop of shootin12007
- Author(s)
  Inagaki, N., Toriyama, M., Shimada, T
- Journal Title
  
  Seikagaku 79
  
  Pages: 799-802
- NAID
  10019550731
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300107
[Journal Article] Shootin1による神経細胞の対称性破壊と極性形成2007
- Author(s)
  稲垣直之, 鳥山道則, 島田忠之
- Journal Title
  
  脳21 10
  
  Pages: 107-109
- Data Source
  KAKENHI-PROJECT-18016020
[Journal Article] 神経極性形成とShootinlのフィードバックループ2007
- Author(s)
  稲垣直之, 鳥山道則, 島田忠之
- Journal Title
  
  生化学 79
  
  Pages: 799-802
- Data Source
  KAKENHI-PROJECT-18016020
[Journal Article] Shootin1による神経細胞の対称性破壊と極性形成2007
- Author(s)
  稲垣直之, 鳥山道則, 島田忠之
- Journal Title
  
  脳21 10
  
  Pages: 107-109
- Data Source
  KAKENHI-PROJECT-18022028
[Journal Article] Neuronal symmetry breaking and polarity formation by shoootin12007
- Author(s)
  Inagaki, N., Toriyama, M., Shimada, T
- Journal Title
  
  Nou 21 10
  
  Pages: 107-109
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300107
[Journal Article] 神経極性形成とShootin1のフィードバックループ2007
- Author(s)
  稲垣直之, 鳥山道則, 島田忠之
- Journal Title
  
  生化学 79
  
  Pages: 799-802
- NAID
  10019550731
- Data Source
  KAKENHI-PROJECT-18022028
[Journal Article] Shootin 1による神経細胞の対称性破壊と極性形成2007
- Author(s)
  稲垣直之, 鳥山道則, 島田忠之
- Journal Title
  
  脳21 10
  
  Pages: 107-109
- Data Source
  KAKENHI-PROJECT-18300107
[Journal Article] Shootinl:a protein involved in organization of an asymmetric signal for neuronal polarization2006
- Author(s)
  Toriyama M. Shimada T., Kim K.B., Mitsuba M., Nomura E., Katsuta K., Sakumura Y., Roepstorff P., Inagaki N.,
- Journal Title
  
  J. Cell Biol. 175
  
  Pages: 147-157
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18300107
[Journal Article] Shootin1: a protein involved in organization of an asymmetric signal for neuronal polarization2006
- Author(s)
  Toriyama, M. Shimada, T., Kim, K.B., Mitsuba, M., Nomura, E, Katsuta, K., Sakumura, Y., Roepstorff, P., Inagaki, N
- Journal Title
  
  J. Cell Biol 175
  
  Pages: 147-157
- NAID
  120005830840
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300107
[Patent] 神経成長円錐局在分子Shootinlもしくはそのスプライシングバリアントを利用した神経軸索の形成・伸長と神経再生への応用2010
- Inventor(s)
  稲垣直之、島田忠之、鳥山道則、小原牧、長瀬隆弘
- Industrial Property Rights Holder
  国立大学法人奈良先端科学技術大学院大学、財団法人かずさディー・エヌ・エー研究所
- Acquisition Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-20300111
[Presentation] Reactive astrocyte-mediated mechanisms of neural disorders in tubular sclerosis complex model mouse2023
- Author(s)
  Tadayuki Shimada, Kanato Yamagata
- Organizer
  第56回日本てんかん学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-22K06493
[Presentation] Activation of NF-κB signaling in astrocyte promotes memory disorder in tubular sclerosis complex model mouse2023
- Author(s)
  Tadayuki Shimada, Hiroko Sugiura, and Kanato Yamagata
- Organizer
  第66回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-22K06493
[Presentation] Reactive astrocyte-mediated mechanisms of memory disorder in tubular sclerosis complex model mouse2022
- Author(s)
  Tadayuki Shimada, Hiroko Sugiura, and Kanato Yamagata
- Organizer
  Neuro2022(第65回日本神経化学会大会)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06493
[Presentation] Astrocyte-mediated social memory deficiency in tubular sclerosis complex model mouse2020
- Author(s)
  Tadayuki Shimada, Hiroko Sugiura, and Kanato Yamagata
- Organizer
  FENS 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07086
[Presentation] Astrocyte-mediated impaired social memory in tubular sclerosis complex model mouse2020
- Author(s)
  Tadayuki Shimada, Hiroko Sugiura, and Kanato Yamagata
- Organizer
  第63回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-17K07086
[Presentation] Inhibition of Rheb improved abnormal social behavior in astrocyte-specific Tsc1 knockout mice2019
- Author(s)
  Tadayuki Shimada, Hiroko Sugiura, and Kanato Yamagata
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K07086
[Presentation] Inhibition of Rheb improved abnormal social behavior in astrocyte-specific Tsc1 knockout mice.2019
- Author(s)
  Tadayuki Shimada, Hiroko Sugiura, and Kanato Yamagata
- Organizer
  42nd Annual Meeting of the Japan Neuroscience Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07086
[Presentation] Memory impairment in astrocyte-specific Tsc1 knockout mice was recovered by Rheb inhibition2018
- Author(s)
  Tadayuki Shimada, Hiroko Sugiura, and Kanato Yamagata
- Organizer
  22nd Biennial Meeting of the International Society for Developmental Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07086
[Presentation] アストロサイト特異的Tsc1ノックアウトマウスにおける記憶障害のメカニズム2018
- Author(s)
  Tadayuki Shimada, Hiroko Sugiura, and Kanato Yamagata
- Organizer
  第６１回日日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-17K07086
[Presentation] Memory impairment in astrocyte-specific Tsc1 knockout mice was recovered by Rheb inhibition2018
- Author(s)
  Tadayuki Shimada, Hiroko Sugiura, and Kanato Yamagata
- Organizer
  22nd Biennial Meeting of the International Society for Developmental Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07086
[Presentation] Loss of neuritin accelerates RGC loss and retinal degeneration in adult mice following optic nerve injury2018
- Author(s)
  Yuriko Azuchi, Kazuhiko Namekata, Tadayuki Shimada, Xiaoli Guo, Atsuko Kimura, Chikako Harada, Atsuko Nishigaki, Kanato Yamagata, Takayuki Harada
- Organizer
  48th Annual Meeting of the Society for Neuroscience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07086
[Presentation] アストロサイト特異的Tsc1欠損マウスにおける神経膠症と行動異常2017
- Author(s)
  島田忠之　杉浦弘子　山形要人
- Organizer
  第５８回日本神経病理学会総会学術研究会
- Data Source
  KAKENHI-PROJECT-17K07086
[Presentation] Astrocyte-specific Tsc1 knockout mice show abnormal behavior and harbor severe gliosis2017
- Author(s)
  Tadayuki Shimada, Hiroko Sugiura, and Kanato Yamagata
- Organizer
  第４０回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-17K07086
[Presentation] Neuritin induces axonal branch formation in hippocampal granule neurons by activating FGF signaling2016
- Author(s)
  Tadayuki Shimada, Tomoyuki Yoshida, and Kanato Yamagata
- Organizer
  第１２１回日本解剖学会総会・全国学術集会
- Place of Presentation
  ビッグパレット福島（福島県・郡山市）
- Year and Date
  2016-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-24700349
[Presentation] Neuritin mediates activity-dependent axonal branch formation through FGF signaling2015
- Author(s)
  Tadayuki Shimada, Tomoyuki Yoshida, and Kanato Yamagata
- Organizer
  第49回日本てんかん学会学術集会
- Place of Presentation
  長崎ブリックホール、長崎新聞文化ホール（長崎県・長崎市）
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-24700349
[Presentation] Activity-dependent axonal branching mediated by neuritin2014
- Author(s)
  Tadayuki Shimada, Tomoyuki Yoshida, and Kanato Yamagata
- Organizer
  International symposium: “New Frontier of Molecular Neuropathology 2014
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24700349
[Presentation] Neuritin mediates activity-dependent axonal branching in hippocampal granule cells.2014
- Author(s)
  Tadayuki Shimada, Tomoyuki Yoshida, and Kanato Yamagata
- Organizer
  Development, Function and disorders of the Nervous system
- Place of Presentation
  Montreal, Canada
- Data Source
  KAKENHI-PROJECT-24700349
[Presentation] Neuritin induces activity-dependent axonal branching in hippocampal granule cells.2013
- Author(s)
  Tadayuki Shimada, Tomoyuki Yoshida, and Kanato Yamagata
- Organizer
  第４７回日本てんかん学会
- Place of Presentation
  北九州
- Data Source
  KAKENHI-PROJECT-24700349
[Presentation] Neuritin induces activity-dependent axonal branching in hippocampal granule cells.2013
- Author(s)
  Tadayuki Shimada, Tomoyuki Yoshida, and Kanato Yamagata
- Organizer
  第36回日本神経科学大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24700349
[Presentation] Neuritin induces activity-dependent axonal branching in hippocampal granule cells2013
- Author(s)
  Tadayuki Shimada, Tomoyuki Yoshida, and Kanato Yamagata
- Organizer
  第３６回日本神経科学大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24700349
[Presentation] Involvement of neuritin in activity-dependent neurite branching in hippocampal neurons.2012
- Author(s)
  Tadayuki Shimada, Tomoyuki Yoshida, and Kanato Yamagata
- Organizer
  第46回日本てんかん学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24700349
[Presentation] Neuronal symmetry-breaking by a positive feedback loop involving neurite length-dependent shootin1 accumulation2010
- Author(s)
  Toriyama, M., Sakumura, Y., Shimada, T., Ishii, S., Inagaki, N.
- Organizer
  The American Society for Cell Biology 50th Annual Meeting
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2010-12-14
- Data Source
  KAKENHI-PROJECT-20300111
[Presentation] Neuronal symmetry-breaking by a positive feedback loop involving neurite length-dependent shootin1 accumulation2010
- Author(s)
  Toriyama M., Sakumura Y., Shimada T., Ishii, S, Inagaki N.
- Organizer
  The American Society for Cell Biology 50th Annual Meeting
- Place of Presentation
  Philadelphia, USA.
- Year and Date
  2010-12-14
- Data Source
  KAKENHI-PROJECT-20300111
[Presentation] Shootin1による神経突起長の計測と神経突起伸長の促進は神経極性形成を誘導する2009
- Author(s)
  鳥山道則、作村諭一、島田忠之、石井信、稲垣直之
- Organizer
  第61回日本細胞生物学会大学
- Place of Presentation
  名古屋
- Year and Date
  2009-06-02
- Data Source
  KAKENHI-PROJECT-20300111
[Presentation] クラッチ分子Shootin1による神経突起伸長機構の解析2009
- Author(s)
  鳥山道則、島田忠之、上口裕之、杉浦忠男、渡邊直樹、稲垣直之
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-20300111
[Presentation] Shootin1による神経突起長の計測と神経突起伸長の促進は神経極性形成を誘導する2009
- Author(s)
  鳥山道則、作村諭一、島田忠之、石井信、稲垣直之
- Organizer
  第61回日本細胞生物学会大会
- Place of Presentation
  名古屋
- Year and Date
  2009-06-02
- Data Source
  KAKENHI-PROJECT-20300111
[Presentation] Shoot inlによる神経突起計測および神経突起伸長の促進は神経極性形成を誘導する2008
- Author(s)
  鳥山道則, 作村諭一, 島田忠之, 石井信, 稲垣直之
- Organizer
  第31回日本分子生物学会・第81回日本生化学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20300111
[Presentation] Shootin1による神経突起計測および神経突起伸長の促進は神経極性形成を誘導する2008
- Author(s)
  鳥山道則、作村諭一、島田忠之、石井信、稲垣直之
- Organizer
  第31回日本分子生物学会・第81回日本生化学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20300111
[Presentation] Shootinlは成長円錐のアクチンフィラメント求心性流動と細胞接着分子Ll-CAMとを連結することによって神経軸索伸長を促進する2008
- Author(s)
  島田忠之, 鳥山道則, 上口裕之, 杉浦忠男, 渡邊直樹, 稲垣直之
- Organizer
  第60回日本細胞生物学会大会ミニシンポジウム細胞突起の形成と発達のメカニズム
- Place of Presentation
  横浜
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-20300111
[Presentation] Shootin1は成長円錐のアクチンフィラメント求心性流動と細胞接着分子L1-CAMとを連結することによって神経軸索伸長を促進する2008
- Author(s)
  島田忠之、鳥山道則、上口裕之、杉浦忠男、渡邊直樹、稲垣直之
- Organizer
  第60回日本細胞生物学会大会ミニシンポジウム「細胞突起の形成と発達のメカニズム」
- Place of Presentation
  横浜
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-20300111
[Presentation] Shootinlと神経突起伸長のPositive feedback loopによる神経極性形成機構2007
- Author(s)
  鳥山道則, 作村諭一, 浅野卓也, 島田忠之, 稲垣直之
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18016020
[Presentation] 新規タンパク質Shootin1は、F-actinの求心的移動とL1-CAMを連結することで神経突起伸長を促進する2007
- Author(s)
  島田忠之、鳥山道則、上口裕之、杉浦忠男、渡邊直樹、稲垣直之
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18300107
[Presentation] 新規タンパク質Shootin1は、F-actinの求心的移動とLl-CAMを連結することで神経突起伸長を促進する2007
- Author(s)
  島田忠之, 鳥山道則, 上口裕之, 杉浦忠男, 渡邊直樹, 稲垣直之
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18016020
[Presentation] 新規タンパク質Shootin1とSingar1による神経極性形成の制御2007
- Author(s)
  稲垣直之、鳥山道則、島田忠之、森達也
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会ワークショップ、From shape to function:ニューロンの形態形成と可塑性を司る分子基盤
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300107
[Presentation] 新規タンパク質ShootinlとSingarlによる神経極性形成の制御2007
- Author(s)
  稲垣直之, 鳥山道則, 島田忠之, 森達也
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会ワークショップ、From shape to function:ニューロンの形態形成と可塑性を司る分子基盤
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18016020
[Presentation] Regulation of neuronal polarity formation by novel proteins shootin1 and singar12007
- Author(s)
  Inagaki, N., Toriyama, M., Shimada, T., Mori, T
- Organizer
  Biochemistry and Molecular Bioloby (BMB) 2007
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300107
[Presentation] Shootin1と神経突起伸長のPositive feedback loopによる神経極性形成機構2007
- Author(s)
  鳥山道則、作村諭一、浅野卓也、島田忠之、稲垣直之
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300107
[Presentation] Shootin1と神経突起伸長のPositive feedback loopによる神経極性形成機構2007
- Author(s)
  鳥山道則, 作村諭一, 浅野卓也, 島田忠之, 稲垣直之
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18022028
[Presentation] 新規タンパク質ShootinalとSingarlによる神経極性形成の制御2007
- Author(s)
  稲垣直之, 鳥山道則, 島田忠之, 森達也
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会ワークションップ、From shape to function:ニューロンの形態形成と可塑性を司る分子基盤
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18022028
[Presentation] Shootin1と神経突起伸長のPositive feedback loopによる神経極性形成機構2007
- Author(s)
  鳥山道則、作村諭一、浅野卓也、島田忠之、稲垣直之
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18300107
[Presentation] Shootin1 Transmits Driving Force of F-actin Flow to L1-CAM for Neurite Elongation2007
- Author(s)
  Shimada, T., Toriyama, M., Uemura K., Sugiura, T., Watanabe, N., Kamiguchi, H., Inagaki, N.
- Organizer
  47th Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-18022028
[Presentation] 新規タンパク質Shootin1は、F-actinの求心的移動とL1-CAMを連結することで神経突起伸長を促進する2007
- Author(s)
  島田忠之, 鳥山道則, 上口裕之, 杉浦忠男, 渡辺直樹, 稲垣直之
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18022028
[Presentation] Shootin1 Transmits Driving Force of F-actin Flow to L1-CAM for Neurite Elongation2007
- Author(s)
  Shimada, T., Toriyama, M., Uemura K., Sugiura, T., Watanabe, N., Kamiguchi, H., and Inagaki, N.
- Organizer
  47th Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  Washington DC, USA
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300107
[Presentation] 新規タンパク質Shootin1とSingar1による神経極性形成の制御2007
- Author(s)
  稲垣直之、鳥山道則、島田忠之、森達也
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会ワークショップ、From shape to function:ニューロンの形態形成と可塑性を司る分子基盤
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-18300107
[Presentation] 新規タンパク質Shootin1は、F-actinの求心的移動とL1-CAMを連結することで神経突起伸長を促進する2007
- Author(s)
  島田忠之、鳥山道則、上口裕之、杉浦忠男、渡邊直樹、稲垣直之
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300107
[Presentation] Neuronal polarity formation by feedback interaction between shoootin1 and neurite length2007
- Author(s)
  Toriyama, M., Sakumura, Y., Asano, T., Shimada, T., Inagaki, N
- Organizer
  Biochemistry and Molecular Bioloby (BMB) 2007
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300107
[Presentation] Shootinl Transmits Driving Force of F-actin Flow to Ll-CAM for Neurite Elongation2007
- Author(s)
  Shimada, T., Toriyama, M., Uemura K., Sugiura, T., Watanabe, N., Kamiguchi, H., lnagaki, N.
- Organizer
  47th Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  Washington DC, USA
- Data Source
  KAKENHI-PROJECT-18016020
[Presentation] Shootin1 interacts with actin retrograde flow and Ll-CAM to promote axon outgrowth2007
- Author(s)
  Shimada, T., Toriyama, M., Kamiguchi, H., Sugiura, T., Watanabe, N., Inagaki, N
- Organizer
  Biochemistry and Molecular Bioloby (BMB) 2007
- Place of Presentation
  Yokohama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300107
[Presentation] 新規タンパク質shootinlは、F-actinの求心的移動とL1-CAMを連結することで神経突起伸長を促進する2007
- Author(s)
  島田忠之
- Organizer
  日本分子生物学会年会
- Place of Presentation
  横浜日本
- Data Source
  KAKENHI-PROJECT-19700291
[Presentation] Shootinl Transmits Driving Force of F-actin-flow to L1-CAM for Neurite Elongation.2007
- Author(s)
  T. Shimada
- Organizer
  Annual Meeting of American Society for Cell Biology
- Place of Presentation
  Washington D.C. U.S.A.
- Data Source
  KAKENHI-PROJECT-19700291
[Presentation] Shootin1 Transmits Driving Force of F-actin Flow to Ll-CAM for Neurite Elongation2007
- Author(s)
  Shimada, T., Toriyama, M., Uemura, K., Sugiura, T., Watanabe, N., Kamiguchi, H., Inagaki, N
- Organizer
  47th Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  Washington DC, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300107
[Presentation] Shootin1 Transmits Driving Force of F-actin Flow to L1-CAM for Neurite Elongation2006
- Author(s)
  Shimada, T., Toriyama, M., Uemura K., Sugiura, T., Watanabe, N., Kamiguchi, H., Lemmon, V., and Inagaki, N.
- Organizer
  Cold Spring Harbor Meeting on Axon Guidance, Synaptogenesis & Neural Plasticity
- Place of Presentation
  New York, USA.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300107
[Presentation] Shootin1 is involved in spontaneous neuronal polarity formation2006
- Author(s)
  Toriyama, M., Shimada, T., Kim, K.B., Mitsuba, M., Nomura, E., Roepstorff, P., and Inagaki, N.
- Organizer
  20th IUBMB International, Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto.
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18300107
[Presentation] Shootin1 is involved in spontaneous neuronal polarity formation2006
- Author(s)
  Toriyama, M., Shimada, T., Kim, K.B., Mitsuba, M., Nomura, E., Roepstorff, P., Inagaki, N
- Organizer
  20th IUBMB International, Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress
- Place of Presentation
  Kyoto
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300107
[Presentation] Shootin1 Transmits Driving Force of F-actin Flow to Ll-CAM for Neurite Elongation2006
- Author(s)
  Shimada, T., Toriyama, M., Uemura K., Sugiura, T., Watanabe, N., Kamiguchi, H., Lemmon, V., Inagaki, N
- Organizer
  Cold Spring Harbor Meeting on Axon Guidance, Synaptogenesis & Neural Plasticity
- Place of Presentation
  New York, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18300107
[Presentation] Neuritin mediates activity-dependent axonal branching in hippocampal granule cells
- Author(s)
  Tadayuki Shimada, Tomoyuki Yoshida, and Kanato Yamagata
- Organizer
  Development, Functions and Disorders of the Nervous System
- Place of Presentation
  Montreal, Canada
- Year and Date
  2014-07-19 – 2014-07-24
- Data Source
  KAKENHI-PROJECT-24700349
[Presentation] Neuritin induces activity-dependent axonal branch formation through FGF signaling
- Author(s)
  Tadayuki Shimada, Tomoyuki Yoshida, and Kanato Yamagata
- Organizer
  第３７回日本神経科学大会
- Place of Presentation
  横浜・パシフィコ横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-24700349
[]

1. INAGAKI Naoyuki (20223216)

# of Collaborated Projects: 4 results

# of Collaborated Products: 47 results
2. 田中秀和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 山形要人

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
4. 杉浦弘子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

(Shimada) (Tadayuki) 島田 忠之

島田 忠之 シマダ タダユキ

SHIMADA Tadayuki 島田 忠之

Research Projects

Research Products

Co-Researchers

神経-グリア間相互作用の調節を通じた、社会行動の制御メカニズムPrincipal Investigator

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Regulatory mechanism of depression and anxiety via the control of axonal branch formationPrincipal Investigator

Principal Investigator

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Role of clutch protein shootin1 in activity-dependent axonal elongationPrincipal Investigator

Principal Investigator

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Mechanism of Neuronal Polarization Mediated by Shootin and Its Roles in the Brain

Principal Investigator

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新規タンパク質shootin1を中心とした軸索伸長を司る基本メカニズムの解析Principal Investigator

Principal Investigator

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Research Institution

細胞が非対称性を獲得する原理の分子レベルおよび数理・数式レベルでのモデル構築

Principal Investigator

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Research Category

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神経細胞が過剰な軸索の形成を抑制する分子機構の解析

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Analysis of a Novel Protein Shootin1, which is involved in organization of an asymmetric signal for neuronal polarization

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神経細胞の極性形成をつかさどる新規タンパク質shootinの機能解析Principal Investigator

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[Journal Article] Spine morphogenesis and synapse formation in tubular sclerosis complex models2022

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[Journal Article] Syntenin: PDZ Protein Regulating Signaling Pathways and Cellular Functions2019

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[Journal Article] Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance.2018

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[Journal Article] Pentylenetetrazole-Induced Kindling Mouse Model.2018

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(Shimada) (Tadayuki) 島田忠之

島田忠之シマダタダユキ

SHIMADA Tadayuki 島田忠之