SASAKI Kensuke 佐々木健介

Researcher Number	80380616
Affiliation (based on the past Project Information) *help	2012: 九州大学, 大学院医学研究院, 助教 2011: Kyushu University, 医学(系)研究科(研究院), 助教 2007 – 2010: Kyushu University, 医学研究院, 助教 2009: 九州大学, 大学院・医学研究院, 助教 2006: Kyushu University, Graduate School of Medical Sciences, Research Associate, 大学院医学研究院, 助手 2004 – 2006: 九州大学, 大学院・医学研究院, 助手
Review Section/Research Field	Principal Investigator Nerve anatomy/Neuropathology Except Principal Investigator Nerve anatomy/Neuropathology / Nerve anatomy/Neuropathology
Keywords	Principal Investigator 遠心カラム / オリゴマー / プリオン蛋白 / プロテアーゼ / ゲル濾過 / 界面活性剤 / Creutzfeldt-Jakob disease / oligomer / immunoblot / prion protein types … More / prion disease / 電気泳動 / 孤発性ヤコブ病 / 凝集体 / クロイツフェルト・ヤコブ病 / イムノブロット / タイプ分類 / プリオン病 / 蛍光抗体 / 全反射顕微鏡 … More Except Principal Investigator アルツハイマー病 / 認知症 / cyclooxygenase / 病理解剖 / 脳血管性認知症 / 生活習慣病 / 耐糖能異常 / 糖尿病 / 神経原線維変化 / 老人斑 / autopsy / alpha-synuclein / pathological criteria / dementia of Lewy body type / Alzheimer's disease / dementia / 痴呆 / 有病率 / レビー小体型痴呆 / 脳血管性痴呆 / 神経原線維型認知症 / α-シヌクレイン / 病理診断基準 / レビー小体型認知症 / コレステロール / 数理解析ソフト / タウ蛋白質 / 脂質代謝異常 / インスリン抵抗性 / 老化性痴呆疾患 / 生活習慣 / 疫学研究 / インスリン Less

Association of life-style related risk factors with the pathology of dementia
- Principal Investigator
  
  IWAKI Toru
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kyushu University
プリオン蛋白オリゴマーの生化学的性質および神経細胞毒性と感染性の検討Principal Investigator
- Principal Investigator
  
  佐々木健介
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kyushu University
Clinicopathological study of risk factors for degenerative dementia : the Hisayama Study
- Principal Investigator
  
  IWAKI Toru
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kyushu University
Simplified method for the detection of prion protein oligomersPrincipal Investigator
- Principal Investigator
  
  SASAKI Kensuke
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kyushu University
Biochemical analysis of abnormal prion protein in the cases with sporadic Creutzfeldt-Jakob disease.Principal Investigator
- Principal Investigator
  
  SASAKI Kensuke
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  KYUSHU UNIVERSITY
Clinicopathological study of dementia : the Hisayama study
- Principal Investigator
  
  IWAKI Toru
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  KYUSHU UNIVERCITY

All 2012 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

[Book] プリオン病と遅発性ウイルス感染症「病理と病理診断」(分担執筆)2010
- Author(s)
  佐々木健介、岩城徹
- Publisher
  金原出版
- Data Source
  KAKENHI-PROJECT-21500337
[Journal Article] Protease-resistant PrP and PrP oligomers in the brain in human prion diseases after intraventricular pentosan polysulfate infusion2012
- Author(s)
  Honda H, Sasaki K, Minaki H, Masui K, Suzuki SO, Doh-Ura K, Iwaki T
- Journal Title
  
  Neuropathology
  
  Volume: 32 Issue: 2 Pages: 124-132
- DOI
  10.1111/j.1440-1789.2011.01245.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300116, KAKENHI-PROJECT-22390172
[Journal Article] 異常プリオン蛋白検出法の変遷 ―神経変性疾患の病態解明に向けて―2010
- Author(s)
  佐々木健介
- Journal Title
  
  福岡医学雑誌 100
  
  Pages: 313-321
- NAID
  120001875161
- Data Source
  KAKENHI-PROJECT-21500337
[Journal Article] Prion protein oligomers in Creutzfeldt-Jakob disease detected by gel-filtration centrifuge columns.2009
- Author(s)
  Minaki H, Sasaki K, Honda H, Iwaki T
- Journal Title
  
  Neuropathology 29(5)
  
  Pages: 536-542
- NAID
  10028192186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300125
[Journal Article] Development of oligomeric prion-protein aggregates in a mouse model of prion disease2009
- Author(s)
  佐々木健介, et al.
- Journal Title
  
  Journal of Pathology 219
  
  Pages: 123-130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500337
[Journal Article] Incidence and survival of dementia in a general population of Japanese elderly: the Hisayama Study.2009
- Author(s)
  Matsui Y, Tanizaki Y, Arima H, Yonemoto K, Doi Y, Ninomiya T, Sasaki K, Iida M, Iwaki T, Kanba S, Kiyohara Y
- Journal Title
  
  J Neurol Neurosurg Psychiatry. 80(4)
  
  Pages: 366-370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300125
[Journal Article] Development of oligomeric prion-protein aggregates in a mouse model of prion disease.2009
- Author(s)
  Sasaki K, Minaki H, Iwaki T
- Journal Title
  
  J. Pathol. 219(1)
  
  Pages: 123-130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300125
[Journal Article] Clinicopathological outline of dementia with Lewy bodies applying the revised criteria: The Hisayama study.2008
- Author(s)
  Fujimi K, Sasaki K, Noda K, Wakisaka Y, Tanizaki Y, Matsui Y, Sekita A, Iida M, Kiyohara Y, Kanba S, Iwaki T
- Journal Title
  
  Brain Pathol. 18(3)
  
  Pages: 317-325
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300125
[Journal Article] Clinicopathological outline of dementia with Lewy bodies applying the revised criteria : the Hisayama study2008
- Author(s)
  Fujimi K, Sasaki K, Noda K, Wakisaka Y, Tanizaki Y, Matsui Y, Sekita A, Iida M, Kiyohara Y, Kanba S, Iwaki T.
- Journal Title
  
  Brain Pathol 18 (3)
  
  Pages: 317-325
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500309
[Journal Article] プリオン病の病理解剖と標本作製の留意点2007
- Author(s)
  佐々木健介、岩城徹
- Journal Title
  
  病理と臨床 25
  
  Pages: 1124-1130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500309
[Journal Article] 退行期うつ病で長期入院中に発症した孤発性Creutzfeldt-Jakob病2007
- Author(s)
  前川敏彦、佐々木健介、安岡克倫、田北昌史、門司晃、神庭重信
- Journal Title
  
  精神科治療学 22(11)
  
  Pages: 1313-1318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500309
[Journal Article] Altered expression of COX-2 in subdivisions of the hippocampus during aging and in Alzheimer's disease: the Hisayama study2007
- Author(s)
  Fujimi K, Noda K, Sasaki K, Wakisaka Y, Tanizaki Y, Iida M, Kiyohara Y, Kanba S, Iwaki T
- Journal Title
  
  Dement Geriatr Cogn Disord. 23
  
  Pages: 423-431
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300125
[Journal Article] Altered Expression of COX-2 in Subdivisions of the Hippocampus during Aging and in Alzheimer's Disease : The Hisayama Study2007
- Author(s)
  Fujimi K, Noda K, Sasaki K, Wakisaka Y, Tanizaki Y, Iida M, Kiyohara Y, Kanba S, Iwaki T.
- Journal Title
  
  Dement Geriatr Cogn Disord 23(6)
  
  Pages: 323-331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500309
[Journal Article] プリオン病の病理解剖と標本作製の留意点2007
- Author(s)
  佐々木健介, ら
- Journal Title
  
  病理と臨床 25
  
  Pages: 1124-1130
- Data Source
  KAKENHI-PROJECT-19500309
[Journal Article] Clusterin expression in follicular dendritic cells associated with prion protein accumulation.2006
- Author(s)
  K.Sasaki et al.
- Journal Title
  
  J. Pathol. 209
  
  Pages: 484-491
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16300112
[Journal Article] Clusterin expression in follicular dendritic cells associated with prion protein accumulation.2006
- Author(s)
  Sasaki K
- Journal Title
  
  J Pathol 209
  
  Pages: 484-491
- Data Source
  KAKENHI-PROJECT-16300112
[Journal Article] Clusterin expression in follicular dendritic cells associated with prion protein accumulation.2006
- Author(s)
  Sasaki K
- Journal Title
  
  J.Pathol. 24
  
  Pages: 327-330
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500232
[Journal Article] Clusterin expression in follicular dendritic cells associated with prion protein accumulation.2006
- Author(s)
  Sasaki K
- Journal Title
  
  J. Pathol. 209
  
  Pages: 484-491
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500232
[Journal Article] CJDの病理学的評価基準2006
- Author(s)
  佐々木健介
- Journal Title
  
  CLINICAL NEUROSCIENCE 24
  
  Pages: 327-330
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17500232
[Journal Article] CJDの病理学的評価基準.2006
- Author(s)
  佐々木健介
- Journal Title
  
  CLINICAL NEUROSCIENCE 24
  
  Pages: 327-330
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500232
[Journal Article] Clusterin expression in follicular dendritic cells associated with prion protein accumulation.2006
- Author(s)
  K.Sasaki
- Journal Title
  
  J.Pathol. 209
  
  Pages: 484-491
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16300112
[Journal Article] Fatal familial insomnia with an unusual prion protein deposition pattern : An autopsy report with an experimental transmission study.2005
- Author(s)
  Sasaki K
- Journal Title
  
  Neuropathol Appl Neurobiol 31
  
  Pages: 80-87
- Data Source
  KAKENHI-PROJECT-16300112
[Journal Article] Fatal familial insomnia with an unusual prion protein deposition pattern : An autopsy report with an experimental transmission study.2005
- Author(s)
  Sasaki K
- Journal Title
  
  Neuropathol Appl Neurobiol 31
  
  Pages: 80-87
- Data Source
  KAKENHI-PROJECT-17500232
[Journal Article] Development of oligomeric prion-protein aggregate s in a mouse model of prion disease
- Author(s)
  Sasaki K, Minaki H, Iwaki T.
- Journal Title
  
  J Pathol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500309
[Journal Article] Prion protein oligomers in Creutzfeldt-Jakob disease detected by gelfiltration centrifuge columns
- Author(s)
  Minaki H, Sasaki K, Honda H, Iwaki T.
- Journal Title
  
  Neuropathology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500309
[Journal Article] Insulin resistance is associated with the pathology of Alzheimer' s disease: the Hisayama Study.
- Author(s)
  Matsuzaki T, Sasaki K, Tanizaki Y, Hata J, Fujimi K, Matui Y, Sekita A, Suzuki SO, Kanba S, Kiyohara Y, Iwaki T
- Journal Title
  
  Neurology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300125
[Presentation] 久山町疫学調査と神経病理2010
- Author(s)
  佐々木健介
- Organizer
  第51回日本神経病理学会
- Place of Presentation
  東京
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-22300116
[Presentation] 久山町疫学調査と神経病理2010
- Author(s)
  佐々木健介、岩城徹
- Organizer
  第51回日本神経病理学会
- Place of Presentation
  砂防会館別館(東京都)
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-22300116
[Presentation] プリオン持続感染細胞株における治療候補薬によるプリオン蛋白重合度の変化2010
- Author(s)
  佐々木健介
- Organizer
  第51回日本神経病理学会
- Place of Presentation
  砂防会館別館(東京都)
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-21500337
[Presentation] 久山町疫学調査と神経病理2010
- Author(s)
  佐々木健介、岩城徹
- Organizer
  第51回日本神経病理学会
- Place of Presentation
  砂防会館別館(東京都)
- Year and Date
  2010-04-24
- Data Source
  KAKENHI-PROJECT-21500337
[Presentation] Effect of therapeutic drugs on prion protein polymerization in a prion-infected cell line2010
- Author(s)
  Sasaki K, et al.
- Organizer
  17th International Congress of Neuropathology
- Place of Presentation
  Salzburg
- Data Source
  KAKENHI-PROJECT-21500337
[Presentation] 多彩なプリオン蛋白沈着パターンを示したMM1+2孤発性クロイツフェルト・ヤコブ病の一剖検例2009
- Author(s)
  佐々木健介
- Organizer
  第50回日本神経病理学会
- Place of Presentation
  高松
- Year and Date
  2009-06-06
- Data Source
  KAKENHI-PROJECT-19300125
[Presentation] 多彩なプリオン蛋白沈着パターンを示したMM1+2孤発性クロイツフェルト・ヤコブ病の一剖検例2009
- Author(s)
  佐々木健介
- Organizer
  第50回日本神経病理学会
- Place of Presentation
  高松
- Year and Date
  2009-06-06
- Data Source
  KAKENHI-PROJECT-21500337
[Presentation] アルツハイマー病と耐糖能異常:久山町認知症研究2009
- Author(s)
  佐々木健介
- Organizer
  第23回老年期認知症研究会
- Place of Presentation
  東京
- Year and Date
  2009-07-25
- Data Source
  KAKENHI-PROJECT-21500337
[Presentation] プリオン病モデルマウスおける重合プリオン蛋白形成の経時的解析2008
- Author(s)
  佐々木健介ら
- Organizer
  第49回日本神経病理学会総会
- Place of Presentation
  東京
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-19500309
[Presentation] プリオン病モデルマウスおける重合プリオン蛋白形成の経時的解析2008
- Author(s)
  佐々木健介
- Organizer
  第49回日本神経病理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19300125
[Presentation] プリオン病モデルマウスにおける重合プリオン蛋白形成の経時的解析2008
- Author(s)
  佐々木健介、皆木晴彦、岩城徹
- Organizer
  第49回日本神経病理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19500309
[Presentation] プリオン蛋白オリゴマーの簡便な検出法2008
- Author(s)
  皆木晴彦、佐々木健介、岩城徹
- Organizer
  第49回日本神経病理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19500309
[Presentation] プリオン病の病理形態学的および蛋白生化学的定量解析の試み2008
- Author(s)
  本田裕之、皆木晴彦、柴野智子、佐々木健介、岩城徹
- Organizer
  第49回日本神経病理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19500309
[Presentation] Time course of the development of PrP aggregates in a mouse model of prion disease2007
- Author(s)
  Sasaki K
- Organizer
  Prion 2007
- Place of Presentation
  英国エジンバラ
- Data Source
  KAKENHI-PROJECT-19300125
[Presentation] Time course of the development of PrP aggregates in a mouse model of prion disease2007
- Author(s)
  Sasaki K, Minaki H, Iwaki T.
- Organizer
  Prion2007
- Place of Presentation
  Edinburgh
- Data Source
  KAKENHI-PROJECT-19500309
[Presentation] 伝達性海綿状脳症におけるシナプス関連蛋白発現の経時的解析2007
- Author(s)
  佐々木健介、皆木晴彦、岩城徹
- Organizer
  第48回日本神経病理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19500309
[Presentation] Time course of the development of PrP aggregates in a mouse model of prion disease2007
- Author(s)
  Sasaki K., et. al.
- Organizer
  Prion 2007
- Place of Presentation
  Edinburgh、英国
- Data Source
  KAKENHI-PROJECT-19500309

1. IWAKI Toru (40221098)

# of Collaborated Projects: 6 results

# of Collaborated Products: 18 results
2. KIYOHARA Yutaka (80161602)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
3. SUZUKI Satoshi (90294917)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. TANIZAKI Yumihiro (30437785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. IIDA Mitsuo (00127961)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SASAKI Kensuke 佐々木 健介

Research Projects

Research Products

Co-Researchers

Association of life-style related risk factors with the pathology of dementia

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

プリオン蛋白オリゴマーの生化学的性質および神経細胞毒性と感染性の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clinicopathological study of risk factors for degenerative dementia : the Hisayama Study

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Simplified method for the detection of prion protein oligomersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Biochemical analysis of abnormal prion protein in the cases with sporadic Creutzfeldt-Jakob disease.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Clinicopathological study of dementia : the Hisayama study

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] プリオン病と遅発性ウイルス感染症「病理と病理診断」(分担執筆)2010

Author(s)

Publisher

Data Source

[Journal Article] Protease-resistant PrP and PrP oligomers in the brain in human prion diseases after intraventricular pentosan polysulfate infusion2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 異常プリオン蛋白検出法の変遷 ―神経変性疾患の病態解明に向けて―2010

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Prion protein oligomers in Creutzfeldt-Jakob disease detected by gel-filtration centrifuge columns.2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Development of oligomeric prion-protein aggregates in a mouse model of prion disease2009

Author(s)

Journal Title

Data Source

[Journal Article] Incidence and survival of dementia in a general population of Japanese elderly: the Hisayama Study.2009

Author(s)

Journal Title

Data Source

[Journal Article] Development of oligomeric prion-protein aggregates in a mouse model of prion disease.2009

Author(s)

Journal Title

Data Source

[Journal Article] Clinicopathological outline of dementia with Lewy bodies applying the revised criteria: The Hisayama study.2008

Author(s)

Journal Title

Data Source

[Journal Article] Clinicopathological outline of dementia with Lewy bodies applying the revised criteria : the Hisayama study2008

Author(s)

Journal Title

Data Source

[Journal Article] プリオン病の病理解剖と標本作製の留意点2007

SASAKI Kensuke 佐々木健介