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Madhyastha Radha  マドゥエスタ ラダ

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MADHYASTHA Radha  マドゥエスタ ラダ

マドウエスタ ラダ  マドウエスタ ラダ

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Researcher Number 80381078
Other IDs
Affiliation (Current) 2025: 宮崎大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2023 – 2024: 宮崎大学, 医学部, 助教
2019 – 2021: 宮崎大学, 医学部, 助教
2012 – 2017: 宮崎大学, 医学部, 助教
2009 – 2010: University of Miyazaki, 医学部, 助教
Review Section/Research Field
Principal Investigator
Plastic surgery / Basic Section 56070:Plastic and reconstructive surgery-related
Except Principal Investigator
Basic Section 55030:Cardiovascular surgery-related / Basic Section 53020:Cardiology-related
Keywords
Principal Investigator
創傷治癒 / microRNA / MicroRNA / マクロファージ / Non=healing wounds / Inflammasome / microRNA-21 / 慢性炎症 / MicroRNAー21 / 炎症 … More / インフラマソーム / Exosome / 難治性創傷 / マクロファージ炎症 / miR-21 / マクロファージ細胞 / TGFb1 / 糖尿病 / マイクロRNA / 創傷治癒学 … More
Except Principal Investigator
左房長軸方向ストレイン / マイクロRNA / 僧帽弁手術 / 左房組織の線維化 / 左房ストレイン / 左房機能 / 一次性僧帽弁閉鎖不全 / 機能性僧帽弁閉鎖不全症 / 弁リモデリング / 僧帽弁 Less
  • Research Projects

    (6 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (4 People)
  •  僧帽弁リモデリング現象への探求:分子細胞生物学的考察を加えた臨床基礎横断研究

    • Principal Investigator
      渡邉 望
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53020:Cardiology-related
    • Research Institution
      University of Miyazaki
  •  FMR治療における病理、遺伝子発現機構からの検証に基づいた左房機能評価の意義の確立

    • Principal Investigator
      古川 貢之
    • Project Period (FY)
      2023 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      University of Miyazaki
  •  Interaction between exosomal miRNA-21 and inflammasome- role in non-healing woundsPrincipal Investigator

    • Principal Investigator
      Madhyastha Radha
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      University of Miyazaki
  •  MicroRNA and macrophage dysregulation: role in prolonged inflammation of chronic non-healing woundsPrincipal Investigator

    • Principal Investigator
      Madhyastha Radha
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      University of Miyazaki
  •  Interaction between miR-21 and TGFbeta: Role in chronic non-healing woundsPrincipal Investigator

    • Principal Investigator
      MADHYASTHA Radha
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      University of Miyazaki
  •  Studying the significance of miRNA in diabetic wound healing using diabetic animal modelsPrincipal Investigator

    • Principal Investigator
      MADHYASTHA Radha
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Plastic surgery
    • Research Institution
      University of Miyazaki

All 2021 2020 2017 2014 2010 Other

All Journal Article Presentation

  • [Journal Article] MicroRNA 21 Elicits a Pro-inflammatory Response in Macrophages, with Exosomes Functioning as Delivery Vehicles2021

    • Author(s)
      Madhyastha Radha、Madhyastha Harishkumar、Nurrahmah Queen Intan、Purbasari Bethasiwi、Maruyama Masugi、Nakajima Yuichi
    • Journal Title

      Inflammation

      Volume: 44 Issue: 4 Pages: 811-823

    • DOI

      10.1007/s10753-021-01415-0

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10010
  • [Journal Article] NFkappaB activation is essential for miR-21 induction by TGFb1 in high glucose conditions.2014

    • Author(s)
      (1)Radha Madhyastha, Harishkumar Madhyastha, Yutthana Pengjam, Yuichi Nakajima, Sayuri Omura, Masugi Maruyama.
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 451 Issue: 4 Pages: 615-621

    • DOI

      10.1016/j.bbrc.2014.08.035

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24592716
  • [Presentation] Pro-inflammatory profile of miR-21 primed exosomes2020

    • Author(s)
      Radha Madhyastha
    • Organizer
      第50回日本創傷治癒学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K10010
  • [Presentation] Aloin prevents osteoclastogenesis via downregulation of microRNA-21.2017

    • Author(s)
      Madhyastha R, H Madhyastha, Y Pengjam, Y Nakajima, M Maruyama
    • Organizer
      22nd International Conference of Functional Foods and Chronic Diseases in Health, Boston, USA
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10943
  • [Presentation] Dysregulation ofurokinase plasminogen activatorsystem during diabetic woundhealing2010

    • Author(s)
      マドゥエスタラダ, マドゥエスタハリシャクマール, 中島雄一, 大村さゆり, 丸山眞杉
    • Organizer
      International Societyof Fibrinolysis and Proteolysis
    • Place of Presentation
      Amsterdam, TheNetherlands
    • Data Source
      KAKENHI-PROJECT-21791748
  • [Presentation] Growth factorsfluctuations duringcollagen-phycocyanin scaffoldapplication in dermal woundhealing2010

    • Author(s)
      マドゥエスタハリシャクマール, マドゥエスタラダ, ドンガナサンドラ, 中島雄一, 大村さゆり, 丸山眞杉
    • Organizer
      87回日本生理学会
    • Place of Presentation
      盛岡
    • Data Source
      KAKENHI-PROJECT-21791748
  • [Presentation] NFkB dependent induction of miR-21 by TGFb1 in high glucose conditions.

    • Author(s)
      (1)マドゥエスタ ラダ,マドゥエスタハリシャクマール,中島融一,大村さゆり,丸山眞杉
    • Organizer
      24th annual meeting of the European Tissue Repair Society
    • Place of Presentation
      Edinburgh, UK
    • Year and Date
      2014-09-10 – 2014-09-12
    • Data Source
      KAKENHI-PROJECT-24592716
  • 1.  渡邉 望 (60319960)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  マドゥエスタ ハリシャクマール (00543951)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  中島 融一 (80372796)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  古川 貢之 (40404446)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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